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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9270908
log Bayes Factor = 254.18
Chromosome 6   position 32,572,148  (GRCh37) Explore rs9270908 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
K51 Ulcerative colitis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
Z93.2 Ileostomy status
1.000 0.000 0.000
# Top node
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
C44.3 Skin of other and unspecified parts of face
1.000 0.000 0.000
J45 Asthma
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.001 0.999
E10.4 With neurological complications
0.000 0.001 0.999
Chapter X Diseases of the respiratory system
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.001 0.999
K51.4 Pseudopolyposis of colon
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.002 0.998
K90-K93 Other diseases of the digestive system
0.000 0.002 0.998
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.002 0.998
C44 Other malignant neoplasms of skin
0.997 0.003 0.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.004 0.996
K51.3 Ulcerative (chronic) rectosigmoiditis
0.996 0.004 0.000
K51.8 Other ulcerative colitis
0.996 0.004 0.000
K70-K77 Diseases of liver
0.000 0.004 0.996
H30-H36 Disorders of choroid and retina
0.000 0.006 0.994
E14.3 With ophthalmic complications
0.000 0.007 0.993
D64.9 Anaemia, unspecified
0.000 0.008 0.992
D60-D64 Aplastic and other anaemias
0.000 0.009 0.991
D64 Other anaemias
0.000 0.009 0.991
E11.1 With ketoacidosis
0.000 0.010 0.990
Chapter VII Diseases of the eye and adnexa
0.000 0.011 0.989
K86 Other diseases of pancreas
0.000 0.015 0.985
E05.9 Thyrotoxicosis, unspecified
0.000 0.015 0.985
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.016 0.984
E10.5 With peripheral circulatory complications
0.000 0.019 0.981
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.021 0.979
L90.0 Lichen sclerosus et atrophicus
0.000 0.021 0.979
K74 Fibrosis and cirrhosis of liver
0.000 0.022 0.978
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.023 0.977
K51.2 Ulcerative (chronic) proctitis
0.977 0.023 0.000
K75 Other inflammatory liver diseases
0.000 0.023 0.977
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.024 0.976
L90 Atrophic disorders of skin
0.000 0.026 0.974
K75.4 Autoimmune hepatitis
0.000 0.027 0.973
H43-H45 Disorders of vitreous body and globe
0.000 0.027 0.973
G35-G37 Demyelinating diseases of the central nervous system
0.970 0.029 0.001
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.030 0.970
E11.3 With ophthalmic complications
0.000 0.030 0.970
H43 Disorders of vitreous body
0.000 0.033 0.967
J43 Emphysema
0.000 0.035 0.965
G37 Other demyelinating diseases of central nervous system
0.964 0.036 0.000
K86.1 Other chronic pancreatitis
0.000 0.036 0.964
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.037 0.963
L40-L45 Papulosquamous disorders
0.000 0.037 0.963
D50-D53 Nutritional anaemias
0.000 0.037 0.963
G37.9 Demyelinating disease of central nervous system, unspecified
0.959 0.041 0.000
J86 Pyothorax
0.000 0.042 0.958
L40 Psoriasis
0.000 0.042 0.958
E10.8 With unspecified complications
0.000 0.045 0.955
E11.2 With renal complications
0.000 0.047 0.953
D50 Iron deficiency anaemia
0.000 0.047 0.953
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.047 0.953
L40.9 Psoriasis, unspecified
0.000 0.048 0.952
D50.9 Iron deficiency anaemia, unspecified
0.000 0.048 0.952
H34 Retinal vascular occlusions
0.000 0.051 0.949
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.051 0.949
Chapter VIII Diseases of the ear and mastoid process
0.000 0.055 0.945
J43.9 Emphysema, unspecified
0.000 0.057 0.943
H60-H62 Diseases of external ear
0.000 0.057 0.943
D80-D89 Certain disorders involving the immune mechanism
0.000 0.061 0.939
H61 Other disorders of external ear
0.000 0.063 0.937
C44.9 Malignant neoplasm of skin, unspecified
0.936 0.064 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.065 0.935
C44.1 Skin of eyelid, including canthus
0.934 0.066 0.000
H43.3 Other vitreous opacities
0.000 0.066 0.933
C44.7 Skin of lower limb, including hip
0.933 0.067 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.069 0.931
H61.0 Perichondritis of external ear
0.000 0.070 0.930
J33 Nasal polyp
0.000 0.071 0.929
J95-J99 Other diseases of the respiratory system
0.000 0.071 0.929
E10.0 With coma
0.000 0.072 0.928
L80 Vitiligo
0.000 0.076 0.924
J33.9 Nasal polyp, unspecified
0.000 0.076 0.924
K74.3 Primary biliary cirrhosis
0.000 0.076 0.924
E11.5 With peripheral circulatory complications
0.000 0.076 0.924
D86 Sarcoidosis
0.000 0.077 0.923
J46 Status asthmaticus
0.000 0.085 0.915
L92.0 Granuloma annulare
0.000 0.085 0.915
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.093 0.907
K86.3 Pseudocyst of pancreas
0.000 0.094 0.906
H43.8 Other disorders of vitreous body
0.000 0.094 0.906
J33.0 Polyp of nasal cavity
0.000 0.095 0.905
J86.9 Pyothorax without fistula
0.000 0.095 0.905
J33.8 Other polyp of sinus
0.000 0.096 0.904
E10.2 With renal complications
0.000 0.097 0.903
K51.5 Mucosal proctocolitis
0.903 0.097 0.000
E03.8 Other specified hypothyroidism
0.000 0.097 0.903
C44.5 Skin of trunk
0.899 0.101 0.000
H34.8 Other retinal vascular occlusions
0.000 0.101 0.899
E11.6 With other specified complications
0.000 0.103 0.897
D86.9 Sarcoidosis, unspecified
0.000 0.109 0.891
E13 Other specified diabetes mellitus
0.000 0.110 0.890
J86.0 Pyothorax with fistula
0.000 0.111 0.889
E06 Thyroiditis
0.000 0.111 0.889
J98 Other respiratory disorders
0.000 0.112 0.888
J30-J39 Other diseases of upper respiratory tract
0.000 0.125 0.875
E07 Other disorders of thyroid
0.000 0.125 0.875
K74.6 Other and unspecified cirrhosis of liver
0.000 0.125 0.875
K72 Hepatic failure, not elsewhere classified
0.000 0.126 0.874
K86.2 Cyst of pancreas
0.000 0.133 0.867
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.136 0.864
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.142 0.858
E10.6 With other specified complications
0.000 0.144 0.856
K74.5 Biliary cirrhosis, unspecified
0.000 0.145 0.855
K86.8 Other specified diseases of pancreas
0.000 0.147 0.853
E14.8 With unspecified complications
0.000 0.148 0.852
H60 Otitis externa
0.000 0.151 0.849
H43.1 Vitreous haemorrhage
0.000 0.156 0.844
E24 Cushing's syndrome
0.000 0.157 0.843
E83 Disorders of mineral metabolism
0.842 0.158 0.000
E16.1 Other hypoglycaemia
0.000 0.163 0.837
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.169 0.831
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.171 0.829
E27 Other disorders of adrenal gland
0.000 0.171 0.829
K73 Chronic hepatitis, not elsewhere classified
0.000 0.174 0.826
H53-H54 Visual disturbances and blindness
0.000 0.175 0.825
E21.0 Primary hyperparathyroidism
0.000 0.177 0.823
K82 Other diseases of gallbladder
0.000 0.179 0.821
E83.3 Disorders of phosphorus metabolism
0.820 0.180 0.000
H35 Other retinal disorders
0.000 0.181 0.819
D86.8 Sarcoidosis of other and combined sites
0.000 0.182 0.818
E13.9 Without complications
0.000 0.183 0.817
J98.4 Other disorders of lung
0.000 0.189 0.811
L40.0 Psoriasis vulgaris
0.000 0.190 0.810
E06.3 Autoimmune thyroiditis
0.000 0.191 0.809
E65-E68 Obesity and other hyperalimentation
0.000 0.191 0.809
J44 Other chronic obstructive pulmonary disease
0.000 0.198 0.802
C44.0 Skin of lip
0.799 0.201 0.000
E14.6 With other specified complications
0.000 0.201 0.798
E07.9 Disorder of thyroid, unspecified
0.000 0.207 0.793
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.209 0.791
C44.6 Skin of upper limb, including shoulder
0.791 0.209 0.000
E40-E46 Malnutrition
0.000 0.210 0.790
L10-L14 Bullous disorders
0.000 0.210 0.790
E27.1 Primary adrenocortical insufficiency
0.000 0.213 0.787
K72.0 Acute and subacute hepatic failure
0.000 0.216 0.784
H60.9 Otitis externa, unspecified
0.000 0.218 0.782
H54 Blindness and low vision
0.000 0.219 0.781
E21.3 Hyperparathyroidism, unspecified
0.000 0.221 0.779
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.223 0.777
L40.8 Other psoriasis
0.000 0.225 0.775
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.233 0.767
H34.2 Other retinal artery occlusions
0.000 0.236 0.764
H61.8 Other specified disorders of external ear
0.000 0.237 0.763
H61.3 Acquired stenosis of external ear canal
0.000 0.241 0.759
H54.7 Unspecified visual loss
0.000 0.242 0.758
E14.2 Withrenal complications
0.000 0.243 0.757
K74.0 Hepatic fibrosis
0.000 0.244 0.756
E14.5 With peripheral circulatory complications
0.000 0.245 0.755
H61.1 Non-infective disorders of pinna
0.000 0.245 0.755
J85 Abscess of lung and mediastinum
0.000 0.247 0.752
E14.4 With neurological complications
0.000 0.248 0.752
L40.1 Generalised pustular psoriasis
0.000 0.249 0.751
H35.2 Other proliferative retinopathy
0.000 0.253 0.747
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.261 0.739
J98.6 Disorders of diaphragm
0.000 0.261 0.739
J43.2 Centrilobular emphysema
0.000 0.264 0.736
D86.1 Sarcoidosis of lymph nodes
0.000 0.265 0.734
E24.9 Cushing's syndrome, unspecified
0.000 0.268 0.732
D80 Immunodeficiency with predominantly antibody defects
0.000 0.270 0.730
K82.8 Other specified diseases of gallbladder
0.000 0.270 0.730
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.274 0.726
J42 Unspecified chronic bronchitis
0.000 0.277 0.723
J98.9 Respiratory disorder, unspecified
0.000 0.279 0.721
H43.2 Crystalline deposits in vitreous body
0.000 0.279 0.721
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.000 0.280 0.720
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
K51.0 Ulcerative (chronic) enterocolitis
0.716 0.284 0.000
E05.5 Thyroid crisis or storm
0.000 0.285 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.285 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.285 0.715
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.285 0.715
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.285 0.715
G37.8 Other specified demyelinating diseases of central nervous system
0.715 0.285 0.000
C44.8 Overlapping lesion of skin
0.715 0.285 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.286 0.714
K77 Liver disorders in diseases classified elsewhere
0.000 0.286 0.714
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.287 0.712
G36 Other acute disseminated demyelination
0.711 0.288 0.000
J45.1 Nonallergic asthma
0.000 0.289 0.711
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.289 0.711
D64.4 Congenital dyserythropoietic anaemia
0.000 0.290 0.710
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.290 0.710
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.290 0.710
D64.0 Hereditary sideroblastic anaemia
0.000 0.290 0.710
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.708 0.292 0.000
E24.0 Pituitary-dependent Cushing's disease
0.000 0.292 0.708
H34.9 Retinal vascular occlusion, unspecified
0.000 0.293 0.707
E66 Obesity
0.000 0.293 0.707
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.294 0.706
L94 Other localised connective tissue disorders
0.000 0.294 0.706
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.294 0.705
K82.9 Disease of gallbladder, unspecified
0.000 0.296 0.704
K74.4 Secondary biliary cirrhosis
0.000 0.299 0.701
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.299 0.701
K75.2 Nonspecific reactive hepatitis
0.000 0.299 0.701
K75.1 Phlebitis of portal vein
0.000 0.299 0.701
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.300 0.699
L87 Transepidermal elimination disorders
0.000 0.300 0.699
L86 Keratoderma in diseases classified elsewhere
0.000 0.300 0.699
L90.9 Atrophic disorder of skin, unspecified
0.000 0.301 0.699
L90.6 Striae atrophicae
0.000 0.301 0.699
L90.4 Acrodermatitis chronica atrophicans
0.000 0.301 0.699
L90.3 Atrophoderma of Pasini and Pierini
0.000 0.301 0.699
L90.2 Anetoderma of Jadassohn-Pellizzari
0.000 0.301 0.699
L90.1 Anetoderma of Schweninger-Buzzi
0.000 0.301 0.699
K71 Toxic liver disease
0.000 0.302 0.698
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.303 0.697
H35.0 Background retinopathy and retinal vascular changes
0.000 0.303 0.697
D53 Other nutritional anaemias
0.000 0.304 0.696
H43.0 Vitreous prolapse
0.000 0.306 0.693
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.307 0.693
J43.1 Panlobular emphysema
0.000 0.308 0.692
J43.0 MacLeod's syndrome
0.000 0.308 0.692
G37.5 Concentric sclerosis [Balo]
0.691 0.308 0.000
G37.4 Subacute necrotising myelitis
0.691 0.308 0.000
G37.2 Central pontine myelinolysis
0.691 0.308 0.000
G37.1 Central demyelination of corpus callosum
0.691 0.308 0.000
G37.0 Diffuse sclerosis
0.691 0.308 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.309 0.691
L44 Other papulosquamous disorders
0.000 0.310 0.690
L41 Parapsoriasis
0.000 0.310 0.690
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.310 0.690
C44.4 Skin of scalp and neck
0.689 0.311 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.312 0.688
J33.1 Polypoid sinus degeneration
0.000 0.312 0.687
L40.4 Guttate psoriasis
0.000 0.313 0.686
L40.3 Pustulosis palmaris et plantaris
0.000 0.313 0.686
L40.2 Acrodermatitis continua
0.000 0.313 0.686
L13 Other bullous disorders
0.000 0.314 0.686
E83.9 Disorder of mineral metabolism, unspecified
0.685 0.315 0.000
H30 Chorioretinal inflammation
0.000 0.315 0.685
D50.1 Sideropenic dysphagia
0.000 0.317 0.683
Chapter IX Diseases of the circulatory system
0.000 0.317 0.683
J98.8 Other specified respiratory disorders
0.000 0.317 0.683
H60.3 Other infective otitis externa
0.000 0.318 0.682
J37 Chronic laryngitis and laryngotracheitis
0.000 0.319 0.681
H34.0 Transient retinal artery occlusion
0.000 0.319 0.681
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.000 0.320 0.680
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.000 0.320 0.680
E29 Testicular dysfunction
0.000 0.320 0.680
D55-D59 Haemolytic anaemias
0.000 0.321 0.678
E66.9 Obesity, unspecified
0.000 0.323 0.677
D62 Acute posthaemorrhagic anaemia
0.000 0.323 0.677
J45.8 Mixed asthma
0.000 0.323 0.677
I10-I15 Hypertensive diseases
0.000 0.324 0.676
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.324 0.676
H34.1 Central retinal artery occlusion
0.000 0.325 0.675
D82 Immunodeficiency associated with other major defects
0.000 0.327 0.673
D81 Combined immunodeficiencies
0.000 0.327 0.673
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.329 0.670
D83 Common variable immunodeficiency
0.000 0.331 0.669
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.333 0.667
E32 Diseases of thymus
0.000 0.333 0.667
E31 Polyglandular dysfunction
0.000 0.333 0.667
E30 Disorders of puberty, not elsewhere classified
0.000 0.333 0.667
J45.0 Predominantly allergic asthma
0.000 0.333 0.667
J96 Respiratory failure, not elsewhere classified
0.000 0.334 0.666
Q80-Q89 Other congenital malformations
0.000 0.335 0.665
J41 Simple and mucopurulent chronic bronchitis
0.000 0.336 0.664
H54.0 Blindness, both eyes
0.000 0.336 0.664
E11.8 With unspecified complications
0.000 0.337 0.663
D86.3 Sarcoidosis of skin
0.000 0.338 0.662
E05.8 Other thyrotoxicosis
0.000 0.339 0.661
H35.8 Other specified retinal disorders
0.000 0.341 0.659
D50.8 Other iron deficiency anaemias
0.000 0.342 0.658
J95.0 Tracheostomy malfunction
0.000 0.346 0.654
H35.6 Retinal haemorrhage
0.000 0.347 0.653
Q60-Q64 Congenital malformations of the urinary system
0.000 0.348 0.652
E03.1 Congenital hypothyroidism without goitre
0.000 0.349 0.651
H60.8 Other otitis externa
0.000 0.350 0.650
E21.4 Other specified disorders of parathyroid gland
0.000 0.350 0.650
J98.2 Interstitial emphysema
0.000 0.351 0.649
E20 Hypoparathyroidism
0.000 0.352 0.648
J85.2 Abscess of lung without pneumonia
0.000 0.353 0.647
K75.8 Other specified inflammatory liver diseases
0.000 0.356 0.644
K72.9 Hepatic failure, unspecified
0.000 0.359 0.641
H61.9 Disorder of external ear, unspecified
0.000 0.359 0.641
E46 Unspecified protein-energy malnutrition
0.000 0.360 0.640
E13.8 With unspecified complications
0.000 0.362 0.638
E13.7 With multiple complications
0.000 0.362 0.638
E13.6 With other specified complications
0.000 0.362 0.638
E13.5 With peripheral circulatory complications
0.000 0.362 0.638
E13.4 With neurological complications
0.000 0.362 0.638
E13.2 With renal complications
0.000 0.362 0.638
E13.1 With ketoacidosis
0.000 0.362 0.638
E13.0 With coma
0.000 0.362 0.638
L43 Lichen planus
0.000 0.362 0.638
E06.5 Other chronic thyroiditis
0.000 0.363 0.637
E06.4 Drug-induced thyroiditis
0.000 0.363 0.637
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.363 0.637
E06.1 Subacute thyroiditis
0.000 0.363 0.637
E06.0 Acute thyroiditis
0.000 0.363 0.637
J98.3 Compensatory emphysema
0.000 0.363 0.637
K51.1 Ulcerative (chronic) ileocolitis
0.637 0.363 0.000
E06.9 Thyroiditis, unspecified
0.000 0.365 0.635
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.635 0.365 0.000
I10 Essential (primary) hypertension
0.000 0.367 0.633
K82.3 Fistula of gallbladder
0.000 0.371 0.629
E11.0 With coma
0.000 0.372 0.628
K90.8 Other intestinal malabsorption
0.000 0.372 0.628
E07.1 Dyshormogenetic goitre
0.000 0.373 0.627
E07.0 Hypersecretion of calcitonin
0.000 0.373 0.627
D64.3 Other sideroblastic anaemias
0.000 0.374 0.625
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.375 0.625
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.376 0.624
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.621 0.379 0.000
H60.5 Acute otitis externa, non-infective
0.000 0.379 0.621
E13.3 With ophthalmic complications
0.000 0.380 0.620
H43.9 Disorder of vitreous body, unspecified
0.000 0.381 0.619
K72.1 Chronic hepatic failure
0.000 0.382 0.617
J43.8 Other emphysema
0.000 0.383 0.616
I15 Secondary hypertension
0.000 0.384 0.616
K82.2 Perforation of gallbladder
0.000 0.384 0.615
K73.9 Chronic hepatitis, unspecified
0.000 0.386 0.614
L13.0 Dermatitis herpetiformis
0.000 0.388 0.612
H35.5 Hereditary retinal dystrophy
0.000 0.389 0.611
H54.2 Low vision, both eyes
0.000 0.391 0.609
H60.2 Malignant otitis externa
0.000 0.391 0.608
H80-H83 Diseases of inner ear
0.000 0.392 0.608
H60.4 Cholesteatoma of external ear
0.000 0.392 0.608
Q85 Phakomatoses, not elsewhere classified
0.000 0.394 0.606
E24.8 Other Cushing's syndrome
0.000 0.395 0.604
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.395 0.604
E24.3 Ectopic ACTH syndrome
0.000 0.395 0.604
E24.2 Drug-induced Cushing's syndrome
0.000 0.395 0.604
E24.1 Nelson's syndrome
0.000 0.395 0.604
E83.8 Other disorders of mineral metabolism
0.604 0.396 0.000
E83.2 Disorders of zinc metabolism
0.604 0.396 0.000
E83.0 Disorders of copper metabolism
0.604 0.396 0.000
E07.8 Other specified disorders of thyroid
0.000 0.397 0.603
E21.2 Other hyperparathyroidism
0.000 0.397 0.603
H35.4 Peripheral retinal degeneration
0.000 0.398 0.602
Q61 Cystic kidney disease
0.000 0.399 0.601
E27.5 Adrenomedullary hyperfunction
0.000 0.406 0.594
E27.0 Other adrenocortical overactivity
0.000 0.406 0.594
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.407 0.592
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.407 0.592
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.407 0.592
D86.0 Sarcoidosis of lung
0.000 0.408 0.592
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.408 0.592
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.411 0.589
L90.8 Other atrophic disorders of skin
0.000 0.411 0.588
H54.1 Blindness, one eye, low vision, other eye
0.000 0.412 0.588
H35.1 Retinopathy of prematurity
0.000 0.413 0.587
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.413 0.587
K82.0 Obstruction of gallbladder
0.000 0.414 0.586
Q89 Other congenital malformations, not elsewhere classified
0.000 0.414 0.586
C44.2 Skin of ear and external auricular canal
0.583 0.417 0.000
E28 Ovarian dysfunction
0.000 0.420 0.580
E67 Other hyperalimentation
0.000 0.420 0.580
E68 Sequelae of hyperalimentation
0.000 0.420 0.580
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.422 0.578
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.425 0.575
E25 Adrenogenital disorders
0.000 0.426 0.574
E27.8 Other specified disorders of adrenal gland
0.000 0.429 0.571
I12 Hypertensive renal disease
0.000 0.430 0.570
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.431 0.569
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.433 0.567
E45 Retarded development following protein-energy malnutrition
0.000 0.433 0.567
E43 Unspecified severe protein-energy malnutrition
0.000 0.433 0.567
E42 Marasmic kwashiorkor
0.000 0.433 0.567
E41 Nutritional marasmus
0.000 0.433 0.567
E40 Kwashiorkor
0.000 0.433 0.567
L10 Pemphigus
0.000 0.434 0.566
L14 Bullous disorders in diseases classified elsewhere
0.000 0.434 0.566
L11 Other acantholytic disorders
0.000 0.434 0.565
C82.0 Small cleaved cell, follicular
0.564 0.436 0.000
E26 Hyperaldosteronism
0.000 0.437 0.563
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.437 0.563
H54.5 Low vision, one eye
0.000 0.440 0.560
H54.3 Unqualified visual loss, both eyes
0.000 0.440 0.560
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.441 0.559
Q61.2 Polycystic kidney, adult type
0.000 0.442 0.558
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.443 0.557
N00-N08 Glomerular diseases
0.000 0.444 0.556
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.000 0.444 0.556
J85.0 Gangrene and necrosis of lung
0.000 0.445 0.554
Chapter XIV Diseases of the genitourinary system
0.000 0.446 0.554
K75.9 Inflammatory liver disease, unspecified
0.000 0.447 0.553
I85 Oesophageal varices
0.000 0.447 0.553
E11.4 With neurological complications
0.000 0.447 0.553
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.449 0.551
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.000 0.449 0.551
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.450 0.550
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.451 0.549
K50-K52 Noninfective enteritis and colitis
0.169 0.451 0.379
Q85.9 Phakomatosis, unspecified
0.000 0.453 0.547
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.545 0.455 0.000
L94.9 Localised connective tissue disorder, unspecified
0.000 0.457 0.543
J37.0 Chronic laryngitis
0.000 0.458 0.542
L94.2 Calcinosis cutis
0.000 0.458 0.542
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.459 0.541
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.459 0.541
I11 Hypertensive heart disease
0.000 0.459 0.541
D58 Other hereditary haemolytic anaemias
0.000 0.459 0.541
I85.9 Oesophageal varices without bleeding
0.000 0.459 0.541
J85.3 Abscess of mediastinum
0.000 0.460 0.539
I86 Varicose veins of other sites
0.000 0.460 0.540
H60.1 Cellulitis of external ear
0.000 0.461 0.539
N05 Unspecified nephritic syndrome
0.000 0.462 0.538
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.537 0.463 0.000
Q83 Congenital malformations of breast
0.000 0.463 0.537
D51 Vitamin B12 deficiency anaemia
0.000 0.466 0.534
Q61.3 Polycystic kidney, unspecified
0.000 0.466 0.534
K81 Cholecystitis
0.000 0.467 0.533
I15.9 Seconday hypertension, unspecified
0.000 0.467 0.533
N48 Other disorders of penis
0.000 0.467 0.533
I70 Atherosclerosis
0.000 0.467 0.533
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.468 0.532
N40-N51 Diseases of male genital organs
0.000 0.468 0.532
Q38-Q45 Other congenital malformations of the digestive system
0.000 0.469 0.531
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.000 0.471 0.529
Q89.2 Congenital malformations of other endocrine glands
0.000 0.471 0.529
G36.0 Neuromyelitis optica [Devic]
0.525 0.474 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.476 0.524
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.476 0.524
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.476 0.524
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.476 0.524
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.476 0.524
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.476 0.524
L84 Corns and callosities
0.000 0.478 0.522
J95.5 Postprocedural subglottic stenosis
0.000 0.479 0.521
J95.4 Mendelson's syndrome
0.000 0.479 0.521
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.479 0.521
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.479 0.521
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.479 0.521
N48.6 Balanitis xerotica obliterans
0.000 0.480 0.520
E27.9 Disorder of adrenal gland, unspecified
0.000 0.480 0.520
C82.3 Follicular lymphoma grade IIIa
0.518 0.482 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.000 0.483 0.517
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.483 0.517
D52 Folate deficiency anaemia
0.000 0.484 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
P90-P96 Other disorders originating in the perinatal period
0.000 0.486 0.514
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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