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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9271588
log Bayes Factor = 289.695
Chromosome 6   position 32,590,953  (GRCh37) Explore rs9271588 on Ensembl!
Variant rs9271588 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.000 1.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
J33.9 Nasal polyp, unspecified
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
L40 Psoriasis
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
M06.3 Rheumatoid nodule
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.000 1.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.000 1.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.999 0.000 0.001
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
D80-D89 Certain disorders involving the immune mechanism
1.000 0.000 0.000
D86 Sarcoidosis
0.999 0.001 0.000
R31 Unspecified haematuria
0.000 0.001 0.999
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
D69 Purpura and other haemorrhagic conditions
0.999 0.001 0.000
J32.9 Chronic sinusitis, unspecified
0.000 0.001 0.999
J32 Chronic sinusitis
0.000 0.001 0.999
J30-J39 Other diseases of upper respiratory tract
0.000 0.001 0.999
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.001 0.999
M45 Ankylosing spondylitis
0.000 0.002 0.998
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.002 0.998
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.003 0.997
M07 Psoriatic and enteropathic arthropathies
0.000 0.003 0.997
M45-M49 Spondylopathies
0.000 0.003 0.997
E10.9 Without complications
0.000 0.004 0.996
M07.3 Other psoriatic arthropathies
0.000 0.005 0.995
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.005 0.995
M06.34 Rheumatoid nodule (Hand)
0.000 0.005 0.995
Chapter X Diseases of the respiratory system
0.000 0.006 0.994
D69.6 Thrombocytopenia, unspecified
0.993 0.007 0.000
D86.0 Sarcoidosis of lung
0.992 0.008 0.000
J45 Asthma
0.000 0.008 0.992
J40-J47 Chronic lower respiratory diseases
0.000 0.010 0.990
M65-M68 Disorders of synovium and tendon
0.000 0.010 0.990
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.010 0.990
M65 Synovitis and tenosynovitis
0.000 0.012 0.988
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.012 0.988
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.013 0.987
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.015 0.985
Chapter IV Endocrine, nutritional and metabolic diseases
0.003 0.017 0.980
L43 Lichen planus
0.000 0.017 0.983
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.018 0.982
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.019 0.981
K90 Intestinal malabsorption
0.981 0.019 0.000
# Top node
0.000 0.022 0.978
E10.4 With neurological complications
0.000 0.022 0.978
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.978 0.022 0.000
E10.3 With ophthalmic complications
0.000 0.023 0.977
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.023 0.977
D68 Other coagulation defects
0.973 0.027 0.000
E10.5 With peripheral circulatory complications
0.000 0.029 0.971
L43.9 Lichen planus, unspecified
0.000 0.031 0.969
J33.8 Other polyp of sinus
0.000 0.036 0.964
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.036 0.964
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.038 0.962
D86.9 Sarcoidosis, unspecified
0.961 0.039 0.000
D50-D53 Nutritional anaemias
0.959 0.041 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.041 0.959
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.043 0.957
E11.4 With neurological complications
0.000 0.045 0.955
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.046 0.954
E00-E07 Disorders of thyroid gland
0.017 0.048 0.936
J33.0 Polyp of nasal cavity
0.000 0.048 0.952
K90.9 Intestinal malabsorption, unspecified
0.949 0.051 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.054 0.946
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.055 0.945
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.057 0.943
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.058 0.942
E03 Other hypothyroidism
0.006 0.060 0.934
J46 Status asthmaticus
0.000 0.061 0.939
D89.2 Hypergammaglobulinaemia, unspecified
0.935 0.065 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.065 0.935
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.067 0.933
J32.4 Chronic pansinusitis
0.000 0.067 0.933
N40 Hyperplasia of prostate
0.000 0.069 0.931
N40-N51 Diseases of male genital organs
0.000 0.071 0.929
L05 Pilonidal cyst
0.000 0.072 0.928
D69.4 Other primary thrombocytopenia
0.927 0.073 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.927 0.073 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.076 0.924
N48 Other disorders of penis
0.000 0.076 0.924
E13 Other specified diabetes mellitus
0.000 0.077 0.923
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.080 0.920
M35.3 Polymyalgia rheumatica
0.000 0.080 0.920
L05.0 Pilonidal cyst with abscess
0.000 0.082 0.918
M20-M25 Other joint disorders
0.000 0.082 0.917
D52 Folate deficiency anaemia
0.915 0.084 0.000
M35 Other systemic involvement of connective tissue
0.008 0.085 0.907
D51 Vitamin B12 deficiency anaemia
0.913 0.087 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.911 0.089 0.000
E10.6 With other specified complications
0.000 0.090 0.910
D55-D59 Haemolytic anaemias
0.910 0.090 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.095 0.905
D68.8 Other specified coagulation defects
0.902 0.098 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.098 0.902
C82.0 Small cleaved cell, follicular
0.000 0.101 0.899
M31 Other necrotising vasculopathies
0.000 0.104 0.896
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.104 0.896
M14 Arthropathies in other diseases classified elsewhere
0.000 0.107 0.893
N48.6 Balanitis xerotica obliterans
0.000 0.107 0.893
E10.8 With unspecified complications
0.000 0.110 0.890
E10.1 With ketoacidosis
0.000 0.114 0.886
N48.0 Leukoplakia of penis
0.000 0.114 0.886
D52.9 Folate deficiency anaemia, unspecified
0.884 0.116 0.000
J09-J18 Influenza and pneumonia
0.000 0.117 0.883
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.118 0.882
Chapter XIV Diseases of the genitourinary system
0.000 0.120 0.880
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.123 0.877
M31.6 Other giant cell arteritis
0.000 0.125 0.875
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.130 0.870
M06.4 Inflammatory polyarthropathy
0.000 0.131 0.869
J35 Chronic diseases of tonsils and adenoids
0.000 0.135 0.865
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.141 0.859
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.000 0.142 0.858
L42 Pityriasis rosea
0.000 0.142 0.858
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.144 0.856
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.144 0.856
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.145 0.855
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.146 0.854
J32.1 Chronic frontal sinusitis
0.000 0.147 0.853
E11.6 With other specified complications
0.000 0.149 0.851
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.848 0.152 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.153 0.847
C82.3 Follicular lymphoma grade IIIa
0.000 0.153 0.846
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.160 0.840
D59 Acquired haemolytic anaemia
0.838 0.162 0.000
M30 Polyarteritis nodosa and related conditions
0.000 0.167 0.833
D89.9 Disorder involving the immune mechanism, unspecified
0.833 0.167 0.000
E13.9 Without complications
0.000 0.167 0.833
N48.9 Disorder of penis, unspecified
0.000 0.168 0.832
N10-N16 Renal tubulo-interstitial diseases
0.000 0.170 0.830
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.825 0.175 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.176 0.824
M14.6 Neuropathic arthropathy
0.000 0.178 0.822
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.820 0.180 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.815 0.185 0.000
E11.1 With ketoacidosis
0.000 0.188 0.812
M06.8 Other specified rheumatoid arthritis
0.000 0.191 0.809
D86.3 Sarcoidosis of skin
0.808 0.191 0.000
M05.8 Other seropositive rheumatoid arthritis
0.000 0.197 0.803
E11.5 With peripheral circulatory complications
0.000 0.199 0.801
N48.5 Ulcer of penis
0.000 0.203 0.797
D68.5 Primary Thrombophilia
0.796 0.204 0.000
D68.0 Von Willebrand's disease
0.795 0.205 0.000
D69.8 Other specified haemorrhagic conditions
0.793 0.207 0.000
D86.1 Sarcoidosis of lymph nodes
0.792 0.208 0.000
K90.8 Other intestinal malabsorption
0.791 0.209 0.000
E11.0 With coma
0.000 0.210 0.790
N10 Acute tubulo-interstitial nephritis
0.000 0.210 0.790
J35.8 Other chronic diseases of tonsils and adenoids
0.000 0.211 0.789
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.788 0.212 0.000
J35.1 Hypertrophy of tonsils
0.000 0.213 0.787
J15 Bacterial pneumonia, not elsewhere classified
0.000 0.215 0.785
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.000 0.218 0.782
D59.1 Other autoimmune haemolytic anaemias
0.779 0.221 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.221 0.779
D68.2 Hereditary deficiency of other clotting factors
0.778 0.222 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.004 0.223 0.774
L40.1 Generalised pustular psoriasis
0.000 0.230 0.770
D69.0 Allergic purpura
0.766 0.233 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.757 0.234 0.009
L43.8 Other lichen planus
0.000 0.234 0.766
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.000 0.236 0.764
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.237 0.763
E13.3 With ophthalmic complications
0.000 0.237 0.763
D68.9 Coagulation defect, unspecified
0.763 0.237 0.000
N49.2 Inflammatory disorders of scrotum
0.000 0.239 0.761
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.242 0.757
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.243 0.757
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.000 0.244 0.756
D69.5 Secondary thrombocytopenia
0.754 0.246 0.000
J85 Abscess of lung and mediastinum
0.000 0.247 0.753
L40.4 Guttate psoriasis
0.000 0.247 0.753
J12 Viral pneumonia, not elsewhere classified
0.000 0.250 0.750
M65.1 Other infective (teno)synovitis
0.000 0.251 0.749
M20 Acquired deformities of fingers and toes
0.000 0.252 0.748
L40.0 Psoriasis vulgaris
0.000 0.252 0.748
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.254 0.746
M25 Other joint disorders, not elsewhere classified
0.000 0.254 0.746
M11 Other crystal arthropathies
0.000 0.255 0.745
J45.8 Mixed asthma
0.000 0.255 0.745
C82.2 Large cell, follicular
0.000 0.256 0.743
E14 Unspecified diabetes mellitus
0.000 0.256 0.744
M12 Other specific arthropathies
0.000 0.257 0.743
M31.7 Microscopic polyangiitis
0.000 0.257 0.743
D68.6 Other Thrombophilia
0.742 0.258 0.000
M25.46 Effusion of joint (Lower leg)
0.000 0.258 0.742
M25.4 Effusion of joint
0.000 0.258 0.742
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.002 0.259 0.740
E10.0 With coma
0.000 0.260 0.740
J13 Pneumonia due to Streptococcus pneumoniae
0.000 0.264 0.736
D86.8 Sarcoidosis of other and combined sites
0.735 0.265 0.000
M00-M03 Infectious arthropathies
0.000 0.269 0.731
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.273 0.726
M07.6 Other enteropathic arthropathies
0.000 0.278 0.722
J32.2 Chronic ethmoidal sinusitis
0.000 0.279 0.721
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.282 0.718
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.283 0.717
M06.38 Rheumatoid nodule (Other)
0.000 0.283 0.717
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.283 0.717
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.283 0.717
M06.33 Rheumatoid nodule (Forearm)
0.000 0.283 0.717
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.283 0.717
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.283 0.717
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.283 0.717
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.283 0.717
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.283 0.717
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.716 0.283 0.001
E05.4 Thyrotoxicosis factitia
0.716 0.283 0.001
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.716 0.283 0.001
D81 Combined immunodeficiencies
0.717 0.283 0.000
M49 Spondylopathies in diseases classified elsewhere
0.000 0.283 0.716
L41 Parapsoriasis
0.000 0.284 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.716
J33.1 Polypoid sinus degeneration
0.000 0.284 0.716
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.284 0.716
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.284 0.716
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.284 0.716
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.284 0.716
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.284 0.716
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.284 0.716
M07.5 Arthropathy in ulcerative colitis
0.000 0.285 0.715
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.285 0.715
M07.2 Psoriatic spondylitis
0.000 0.285 0.715
M07.1 Arthritis mutilans
0.000 0.285 0.715
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.285 0.715
M65.2 Calcific tendinitis
0.000 0.285 0.715
J45.1 Nonallergic asthma
0.000 0.286 0.714
G37 Other demyelinating diseases of central nervous system
0.712 0.286 0.002
M07.38 Other psoriatic arthropathies (Other)
0.000 0.286 0.714
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.286 0.714
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.286 0.714
C82.4 Follicular lymphoma grade IIIb
0.000 0.287 0.713
L40.8 Other psoriasis
0.000 0.287 0.712
N49.8 Inflammatory disorders of other specified male genital organs
0.000 0.288 0.712
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.288 0.712
D67 Hereditary factor IX deficiency
0.711 0.289 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.290 0.710
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.000 0.291 0.708
C82.6 Cutaneous follicle centre lymphoma
0.000 0.292 0.708
C82.5 Diffuse follicle centre lymphoma
0.000 0.292 0.708
E11.8 With unspecified complications
0.000 0.293 0.707
L44 Other papulosquamous disorders
0.000 0.293 0.707
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.294 0.706
L43.3 Subacute (active) lichen planus
0.000 0.295 0.705
L43.2 Lichenoid drug reaction
0.000 0.295 0.705
L43.1 Bullous lichen planus
0.000 0.295 0.705
L43.0 Hypertrophic lichen planus
0.000 0.295 0.705
M05.2 Rheumatoid vasculitis
0.000 0.296 0.704
K90.3 Pancreatic steatorrhoea
0.703 0.297 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.703 0.297 0.000
K90.1 Tropical sprue
0.703 0.297 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.297 0.703
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.299 0.701
D89.3 Immune reconstitution syndrome
0.701 0.299 0.000
M46 Other inflammatory spondylopathies
0.000 0.301 0.699
E10.7 With multiple complications
0.000 0.301 0.698
M08 Juvenile arthritis
0.000 0.303 0.697
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.304 0.696
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.696 0.304 0.000
M14.2 Diabetic arthropathy
0.000 0.304 0.696
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.305 0.695
D60-D64 Aplastic and other anaemias
0.693 0.307 0.000
D56 Thalassaemia
0.692 0.308 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.308 0.691
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.311 0.689
J11 Influenza, virus not identified
0.000 0.311 0.689
J32.3 Chronic sphenoidal sinusitis
0.000 0.312 0.688
J41 Simple and mucopurulent chronic bronchitis
0.000 0.312 0.688
M31.3 Wegener's granulomatosis
0.000 0.313 0.687
D57 Sickle-cell disorders
0.686 0.314 0.000
D68.1 Hereditary factor XI deficiency
0.685 0.315 0.000
N25-N29 Other disorders of kidney and ureter
0.000 0.315 0.685
L00 Staphylococcal scalded skin syndrome
0.000 0.316 0.684
J86 Pyothorax
0.000 0.317 0.683
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.012 0.317 0.671
E00 Congenital iodine-deficiency syndrome
0.012 0.317 0.671
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.682 0.318 0.001
L01 Impetigo
0.000 0.319 0.681
D69.1 Qualitative platelet defects
0.679 0.320 0.000
J15.0 Pneumonia due to Klebsiella pneumoniae
0.000 0.322 0.678
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.322 0.678
E03.1 Congenital hypothyroidism without goitre
0.004 0.323 0.673
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.323 0.676
E10.2 With renal complications
0.000 0.325 0.675
D51.8 Other vitamin B12 deficiency anaemias
0.675 0.325 0.000
E11.7 With multiple complications
0.000 0.326 0.674
E03.5 Myxoedema coma
0.005 0.326 0.669
E03.4 Atrophy of thyroid (acquired)
0.005 0.326 0.669
E03.3 Postinfectious hypothyroidism
0.005 0.326 0.669
E40-E46 Malnutrition
0.002 0.327 0.671
E06 Thyroiditis
0.009 0.327 0.664
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.329 0.671
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.000 0.331 0.669
J17 Pneumonia in diseases classified elsewhere
0.000 0.333 0.667
N99-N99 Other disorders of the genitourinary system
0.000 0.337 0.663
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.338 0.662
E13.8 With unspecified complications
0.000 0.338 0.662
E13.7 With multiple complications
0.000 0.338 0.662
E13.6 With other specified complications
0.000 0.338 0.662
E13.5 With peripheral circulatory complications
0.000 0.338 0.662
E13.4 With neurological complications
0.000 0.338 0.662
E13.2 With renal complications
0.000 0.338 0.662
E13.1 With ketoacidosis
0.000 0.338 0.662
E13.0 With coma
0.000 0.338 0.662
D89.1 Cryoglobulinaemia
0.661 0.339 0.000
D68.4 Acquired coagulation factor deficiency
0.660 0.340 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.340 0.659
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.341 0.659
M65.0 Abscess of tendon sheath
0.000 0.341 0.659
J15.8 Other bacterial pneumonia
0.000 0.341 0.659
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.343 0.657
D52.8 Other folate deficiency anaemias
0.656 0.343 0.000
D52.1 Drug-induced folate deficiency anaemia
0.656 0.343 0.000
D52.0 Dietary folate deficiency anaemia
0.656 0.343 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.006 0.344 0.651
M35.6 Relapsing panniculitis [Weber-Christian]
0.006 0.344 0.651
M35.5 Multifocal fibrosclerosis
0.006 0.344 0.651
M35.4 Diffuse (eosinophilic) fasciitis
0.006 0.344 0.651
N44 Torsion of testis
0.000 0.344 0.656
M25.40 Effusion of joint (Multiple sites)
0.000 0.345 0.655
D51.2 Transcobalamin II deficiency
0.655 0.345 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.655 0.345 0.000
D59.9 Acquired haemolytic anaemia, unspecified
0.654 0.346 0.000
D55 Anaemia due to enzyme disorders
0.653 0.347 0.000
M06.1 Adult-onset Still's disease
0.000 0.349 0.650
M31.8 Other specified necrotising vasculopathies
0.000 0.350 0.650
M30.0 Polyarteritis nodosa
0.000 0.351 0.649
J95-J99 Other diseases of the respiratory system
0.000 0.353 0.647
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.000 0.353 0.647
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.646 0.354 0.000
M31.2 Lethal midline granuloma
0.000 0.357 0.642
D61 Other aplastic anaemias
0.642 0.358 0.000
M31.9 Necrotising vasculopathy, unspecified
0.000 0.359 0.641
E14.6 With other specified complications
0.000 0.360 0.640
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.360 0.640
M14.4 Arthropathy in amyloidosis
0.000 0.360 0.640
M14.3 Lipoid dermatoarthritis
0.000 0.360 0.640
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.360 0.640
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.360 0.640
J35.2 Hypertrophy of adenoids
0.000 0.360 0.640
E05.8 Other thyrotoxicosis
0.638 0.362 0.001
J12.9 Viral pneumonia, unspecified
0.000 0.363 0.637
M46.1 Sacro-iliitis, not elsewhere classified
0.000 0.363 0.637
J10 Influenza due to identified influenza virus
0.000 0.364 0.636
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.365 0.635
D82 Immunodeficiency associated with other major defects
0.634 0.366 0.000
J09 Influenza due to certain identified influenza virus
0.000 0.367 0.633
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.367 0.633
D83 Common variable immunodeficiency
0.632 0.368 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.369 0.631
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.369 0.631
J85.2 Abscess of lung without pneumonia
0.000 0.370 0.630
D69.9 Haemorrhagic condition, unspecified
0.630 0.370 0.000
D84 Other immunodeficiencies
0.624 0.376 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.377 0.623
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.377 0.623
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.377 0.623
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.377 0.623
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.377 0.623
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.377 0.623
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.377 0.623
M20.0 Deformity of finger(s)
0.000 0.377 0.623
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.377 0.623
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.378 0.622
N26 Unspecified contracted kidney
0.000 0.378 0.622
D51.3 Other dietary vitamin B12 deficiency anaemia
0.621 0.378 0.000
D66 Hereditary factor VIII deficiency
0.621 0.378 0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids
0.000 0.380 0.620
M25.8 Other specified joint disorders
0.000 0.380 0.620
E02 Subclinical iodine-deficiency hypothyroidism
0.012 0.380 0.607
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.000 0.382 0.618
M20.4 Other hammer toe(s) (acquired)
0.000 0.383 0.617
L04 Acute lymphadenitis
0.000 0.385 0.615
M66 Spontaneous rupture of synovium and tendon
0.000 0.385 0.615
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.386 0.614
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.386 0.614
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.386 0.614
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.386 0.614
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.386 0.614
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.386 0.614
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.386 0.614
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.386 0.614
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.387 0.613
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.387 0.613
J32.0 Chronic maxillary sinusitis
0.000 0.388 0.612
E14.3 With ophthalmic complications
0.000 0.390 0.610
G37.9 Demyelinating disease of central nervous system, unspecified
0.609 0.391 0.000
M20.5 Other deformities of toe(s) (acquired)
0.000 0.392 0.608
G37.8 Other specified demyelinating diseases of central nervous system
0.606 0.393 0.001
M65.8 Other synovitis and tenosynovitis
0.000 0.393 0.606
J37 Chronic laryngitis and laryngotracheitis
0.000 0.394 0.606
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.000 0.395 0.605
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.397 0.603
M11.2 Other chondrocalcinosis
0.000 0.397 0.603
D59.8 Other acquired haemolytic anaemias
0.601 0.399 0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.601 0.399 0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.601 0.399 0.000
D59.4 Other nonautoimmune haemolytic anaemias
0.601 0.399 0.000
D59.3 Haemolytic-uraemic syndrome
0.601 0.399 0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.601 0.399 0.000
J15.4 Pneumonia due to other streptococci
0.000 0.400 0.600
D58 Other hereditary haemolytic anaemias
0.600 0.400 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.000 0.402 0.597
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.000 0.402 0.597
M30.2 Juvenile polyarteritis
0.000 0.402 0.597
D61.9 Aplastic anaemia, unspecified
0.597 0.403 0.000
J43 Emphysema
0.000 0.403 0.597
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.593 0.407 0.001
M35.2 Behcet's disease
0.006 0.409 0.585
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ
0.000 0.410 0.590
J86.0 Pyothorax with fistula
0.000 0.410 0.590
J85.1 Abscess of lung with pneumonia
0.000 0.411 0.589
N48.4 Impotence of organic origin
0.000 0.412 0.588
N48.2 Other inflammatory disorders of penis
0.000 0.416 0.584
E14.4 With neurological complications
0.000 0.419 0.581
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.420 0.580
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.420 0.580
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.420 0.580
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.420 0.580
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.420 0.580
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.420 0.580
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.420 0.580
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.420 0.580
E03.8 Other specified hypothyroidism
0.004 0.421 0.575
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.421 0.579
M65.14 Other infective (teno)synovitis (Hand)
0.000 0.422 0.578
J15.1 Pneumonia due to Pseudomonas
0.000 0.423 0.577
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.424 0.576
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.424 0.576
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.424 0.576
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.424 0.576
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.424 0.576
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.424 0.576
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.424 0.576
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.424 0.576
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.424 0.576
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.427 0.425 0.148
E06.3 Autoimmune thyroiditis
0.002 0.427 0.571
D59.0 Drug-induced autoimmune haemolytic anaemia
0.571 0.429 0.000
M35.8 Other specified systemic involvement of connective tissue
0.006 0.432 0.562
E16 Other disorders of pancreatic internal secretion
0.001 0.432 0.567
J12.2 Parainfluenza virus pneumonia
0.000 0.434 0.566
J85.0 Gangrene and necrosis of lung
0.000 0.434 0.566
J15.3 Pneumonia due to streptococcus, group B
0.000 0.437 0.563
M31.1 Thrombotic microangiopathy
0.000 0.438 0.562
M12.3 Palindromic rheumatism
0.000 0.445 0.555
M25.47 Effusion of joint (Ankle and foot)
0.000 0.445 0.555
M00 Pyogenic arthritis
0.000 0.446 0.554
N14.1 Nephropathy induced by other drugs, medicaments and biological substances
0.000 0.447 0.553
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.000 0.447 0.553
E14.5 With peripheral circulatory complications
0.000 0.448 0.552
J15.5 Pneumonia due to Escherichia coli
0.000 0.448 0.552
D69.2 Other nonthrombocytopenic purpura
0.551 0.448 0.000
D61.0 Constitutional aplastic anaemia
0.549 0.451 0.000
N25 Disorders resulting from impaired renal tubular function
0.000 0.453 0.547
N48.8 Other specified disorders of penis
0.000 0.453 0.547
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.454 0.546
J12.1 Respiratory syncytial virus pneumonia
0.000 0.455 0.545
D53 Other nutritional anaemias
0.545 0.455 0.000
M25.44 Effusion of joint (Hand)
0.000 0.457 0.543
E11.3 With ophthalmic complications
0.000 0.457 0.543
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.459 0.541
J85.3 Abscess of mediastinum
0.000 0.460 0.540
J11.1 Influenza with other respiratory manifestations, virus not identified
0.000 0.460 0.540
M12.2 Villonodular synovitis (pigmented)
0.000 0.460 0.539

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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