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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9274569
log Bayes Factor = 284.288
Chromosome 6   position 32,635,092  (GRCh37) Explore rs9274569 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
J45.9 Asthma, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
D64.9 Anaemia, unspecified
0.993 0.007 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.989 0.011 0.000
E10-E14 Diabetes mellitus
0.986 0.014 0.000
E10 Insulin-dependent diabetes mellitus
0.979 0.021 0.000
E10.9 Without complications
0.978 0.022 0.000
D00-D09 In situ neoplasms
0.975 0.025 0.000
D06 Carcinoma in situ of cervix uteri
0.973 0.027 0.000
D06.9 Cervix, unspecified
0.972 0.028 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.969 0.031 0.000
D07.1 Vulva
0.966 0.034 0.000
K90 Intestinal malabsorption
0.960 0.040 0.000
K90.9 Intestinal malabsorption, unspecified
0.950 0.050 0.000
E20-E35 Disorders of other endocrine glands
0.948 0.052 0.000
D04 Carcinoma in situ of skin
0.947 0.053 0.000
G35 Multiple sclerosis
0.000 0.067 0.933
N48 Other disorders of penis
0.931 0.069 0.000
N48.6 Balanitis xerotica obliterans
0.930 0.070 0.000
E27 Other disorders of adrenal gland
0.921 0.079 0.000
N48.1 Balanoposthitis
0.917 0.083 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.916 0.084 0.000
E14 Unspecified diabetes mellitus
0.914 0.086 0.000
E27.1 Primary adrenocortical insufficiency
0.908 0.092 0.000
D03 Melanoma in situ
0.906 0.094 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.904 0.096 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.900 0.100 0.000
N48.0 Leukoplakia of penis
0.884 0.116 0.000
D04.7 Skin of lower limb, including hip
0.883 0.117 0.000
N40-N51 Diseases of male genital organs
0.876 0.124 0.000
E24 Cushing's syndrome
0.872 0.128 0.000
D07.4 Penis
0.857 0.143 0.000
E13 Other specified diabetes mellitus
0.854 0.146 0.000
E14.3 With ophthalmic complications
0.854 0.146 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.852 0.147 0.000
E16 Other disorders of pancreatic internal secretion
0.843 0.157 0.000
E21.0 Primary hyperparathyroidism
0.836 0.164 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.825 0.175 0.000
L72.1 Trichilemmal cyst
0.000 0.181 0.819
D04.9 Skin, unspecified
0.817 0.183 0.000
D03.2 Melanoma in situ of ear and external auricular canal
0.806 0.194 0.000
E03.8 Other specified hypothyroidism
0.804 0.196 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.801 0.199 0.000
E83.1 Disorders of iron metabolism
0.000 0.200 0.800
D03.5 Melanoma in situ of trunk
0.797 0.203 0.000
E05.8 Other thyrotoxicosis
0.795 0.205 0.000
D04.5 Skin of trunk
0.791 0.209 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.790 0.210 0.000
E10.0 With coma
0.789 0.211 0.000
D04.4 Skin of scalp and neck
0.773 0.227 0.000
N45 Orchitis and epididymitis
0.770 0.230 0.000
D04.3 Skin of other and unspecified parts of face
0.764 0.236 0.000
E27.2 Addisonian crisis
0.763 0.237 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.238 0.762
E27.3 Drug-induced adrenocortical insufficiency
0.759 0.241 0.000
E13.9 Without complications
0.757 0.243 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.755 0.245 0.000
E14.8 With unspecified complications
0.754 0.246 0.000
E24.0 Pituitary-dependent Cushing's disease
0.753 0.247 0.000
D06.1 Exocervix
0.753 0.247 0.000
E14.1 With ketoacidosis
0.752 0.248 0.000
E07 Other disorders of thyroid
0.750 0.250 0.000
T42.4 Benzodiazepines
0.000 0.254 0.746
E14.4 With neurological complications
0.743 0.257 0.000
T43.2 Other and unspecified antidepressants
0.000 0.258 0.742
L72 Follicular cysts of skin and subcutaneous tissue
0.000 0.258 0.742
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.259 0.741
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.261 0.739
E10.1 With ketoacidosis
0.738 0.262 0.000
E10.6 With other specified complications
0.737 0.263 0.000
E16.1 Other hypoglycaemia
0.731 0.268 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.269 0.731
D09 Carcinoma in situ of other and unspecified sites
0.727 0.273 0.000
D03.8 Melanoma in situ of other sites
0.722 0.278 0.000
D07.2 Vagina
0.722 0.278 0.000
E14.2 Withrenal complications
0.721 0.279 0.000
E31 Polyglandular dysfunction
0.719 0.281 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.282 0.718
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
D03.0 Melanoma in situ of lip
0.716 0.284 0.000
N48.9 Disorder of penis, unspecified
0.709 0.291 0.000
E10.4 With neurological complications
0.708 0.292 0.000
E24.9 Cushing's syndrome, unspecified
0.708 0.292 0.000
E12 Malnutrition-related diabetes mellitus
0.707 0.293 0.000
K90.8 Other intestinal malabsorption
0.706 0.293 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.000 0.296 0.704
E20 Hypoparathyroidism
0.702 0.298 0.000
N48.5 Ulcer of penis
0.701 0.299 0.000
E24.2 Drug-induced Cushing's syndrome
0.701 0.299 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.700 0.300 0.000
E03.1 Congenital hypothyroidism without goitre
0.698 0.301 0.000
D06.7 Other parts of cervix
0.698 0.302 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.696 0.304 0.000
E21.4 Other specified disorders of parathyroid gland
0.695 0.305 0.000
D07.6 Other and unspecified male genital organs
0.695 0.305 0.000
D07.3 Other and unspecified female genital organs
0.695 0.305 0.000
K90.3 Pancreatic steatorrhoea
0.688 0.312 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.688 0.312 0.000
K90.1 Tropical sprue
0.688 0.312 0.000
D07.0 Endometrium
0.687 0.312 0.000
L72.0 Epidermal cyst
0.000 0.313 0.687
T42.0 Hydantoin derivatives
0.000 0.314 0.686
D01.3 Anus and anal canal
0.686 0.314 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.686 0.314 0.000
D06.0 Endocervix
0.685 0.315 0.000
J45 Asthma
0.680 0.320 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.680 0.320 0.000
E32 Diseases of thymus
0.680 0.320 0.000
E30 Disorders of puberty, not elsewhere classified
0.680 0.320 0.000
D04.8 Skin of other sites
0.679 0.321 0.000
D04.0 Skin of lip
0.679 0.321 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.679 0.321 0.000
N44 Torsion of testis
0.678 0.322 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.323 0.677
E10.7 With multiple complications
0.672 0.328 0.000
D01.0 Colon
0.670 0.330 0.000
E40-E46 Malnutrition
0.668 0.332 0.000
L60-L75 Disorders of skin appendages
0.010 0.337 0.653
E02 Subclinical iodine-deficiency hypothyroidism
0.662 0.338 0.000
E27.5 Adrenomedullary hyperfunction
0.660 0.340 0.000
E27.0 Other adrenocortical overactivity
0.660 0.340 0.000
E14.7 With multiple complications
0.656 0.344 0.000
E14.0 With coma
0.656 0.344 0.000
N48.8 Other specified disorders of penis
0.651 0.349 0.000
E25 Adrenogenital disorders
0.650 0.349 0.000
D04.1 Skin of eyelid, including canthus
0.650 0.350 0.000
D03.9 Melanoma in situ, unspecified
0.650 0.350 0.000
E21.2 Other hyperparathyroidism
0.649 0.351 0.000
E15 Nondiabetic hypoglycaemic coma
0.648 0.352 0.000
D04.2 Skin of ear and external auricular canal
0.647 0.353 0.000
D02.2 Bronchus and lung
0.647 0.353 0.000
E14.5 With peripheral circulatory complications
0.646 0.354 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.002 0.356 0.642
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.643 0.357 0.000
E10.8 With unspecified complications
0.642 0.358 0.000
L40.5 Arthropathic psoriasis
0.000 0.361 0.639
D64 Other anaemias
0.633 0.367 0.000
E06 Thyroiditis
0.629 0.371 0.000
L71 Rosacea
0.003 0.371 0.626
E10.2 With renal complications
0.628 0.371 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.625 0.375 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.625 0.375 0.000
E24.3 Ectopic ACTH syndrome
0.625 0.375 0.000
E24.1 Nelson's syndrome
0.625 0.375 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.376 0.623
E24.8 Other Cushing's syndrome
0.623 0.377 0.000
E07.9 Disorder of thyroid, unspecified
0.621 0.379 0.000
E13.3 With ophthalmic complications
0.619 0.380 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.186 0.384 0.429
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.384 0.615
D03.4 Melanoma in situ of scalp and neck
0.614 0.386 0.000
E13.8 With unspecified complications
0.613 0.387 0.000
E13.7 With multiple complications
0.613 0.387 0.000
E13.6 With other specified complications
0.613 0.387 0.000
E13.5 With peripheral circulatory complications
0.613 0.387 0.000
E13.4 With neurological complications
0.613 0.387 0.000
E13.2 With renal complications
0.613 0.387 0.000
E13.1 With ketoacidosis
0.613 0.387 0.000
E13.0 With coma
0.613 0.387 0.000
D09.1 Other and unspecified urinary organs
0.611 0.389 0.000
T42.1 Iminostilbenes
0.000 0.393 0.607
L70 Acne
0.004 0.393 0.603
D03.7 Melanoma in situ of lower limb, including hip
0.605 0.395 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.605 0.395 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.605 0.395 0.000
E16.4 Abnormal secretion of gastrin
0.605 0.395 0.000
E16.3 Increased secretion of glucagon
0.605 0.395 0.000
L40-L45 Papulosquamous disorders
0.161 0.398 0.441
L71.1 Rhinophyma
0.001 0.401 0.598
L40 Psoriasis
0.020 0.402 0.578
T50.4 Drugs affecting uric acid metabolism
0.000 0.407 0.593
D01.9 Digestive organ, unspecified
0.592 0.408 0.000
D01.7 Other specified digestive organs
0.592 0.408 0.000
D01.5 Liver, gallbladder and bile ducts
0.592 0.408 0.000
D01.4 Other and unspecified parts of intestine
0.592 0.408 0.000
D01.1 Rectosigmoid junction
0.592 0.408 0.000
E16.2 Hypoglycaemia, unspecified
0.591 0.409 0.000
D02.0 Larynx
0.583 0.417 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.417 0.583
N51 Disorders of male genital organs in diseases classified elsewhere
0.580 0.420 0.000
E29 Testicular dysfunction
0.577 0.423 0.000
N48.4 Impotence of organic origin
0.576 0.423 0.000
G37 Other demyelinating diseases of central nervous system
0.001 0.424 0.576
E21.3 Hyperparathyroidism, unspecified
0.575 0.425 0.000
T50.8 Diagnostic agents
0.000 0.425 0.574
D03.1 Melanoma in situ of eyelid, including canthus
0.571 0.429 0.000
N48.2 Other inflammatory disorders of penis
0.569 0.431 0.000
D02.4 Respiratory system, unspecified
0.566 0.434 0.000
D02.3 Other parts of respiratory system
0.566 0.434 0.000
D02.1 Trachea
0.566 0.434 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.000 0.434 0.566
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.563 0.437 0.000
E28 Ovarian dysfunction
0.563 0.437 0.000
N48.3 Priapism
0.562 0.437 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.559 0.440 0.000
L40.9 Psoriasis, unspecified
0.000 0.444 0.556
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.555 0.444 0.000
E31.0 Autoimmune polyglandular failure
0.555 0.444 0.000
J45.0 Predominantly allergic asthma
0.555 0.445 0.000
D01.2 Rectum
0.554 0.446 0.000
E20.1 Pseudohypoparathyroidism
0.552 0.448 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.000 0.450 0.550
L70.0 Acne vulgaris
0.002 0.450 0.548
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.549 0.451 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.453 0.547
T42.2 Succinimides and oxazolidinediones
0.000 0.453 0.547
E14.6 With other specified complications
0.541 0.458 0.000
N46 Male infertility
0.541 0.458 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.459 0.541
D09.9 Carcinoma in situ, unspecified
0.539 0.461 0.000
E07.1 Dyshormogenetic goitre
0.538 0.462 0.000
E07.0 Hypersecretion of calcitonin
0.538 0.462 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.463 0.537
J45.1 Nonallergic asthma
0.536 0.464 0.000
T42.3 Barbiturates
0.000 0.467 0.533
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.467 0.533
L72.2 Steatocystoma multiplex
0.000 0.468 0.532
T36 Poisoning by systemic antibiotics
0.000 0.468 0.532
T43.9 Psychotropic drug, unspecified
0.000 0.468 0.532
T43.8 Other psychotropic drugs, not elsewhere classified
0.000 0.468 0.532
D09.7 Carcinoma in situ of other specified sites
0.521 0.479 0.000
D09.3 Thyroid and other endocrine glands
0.521 0.479 0.000
D09.2 Eye
0.521 0.479 0.000
E31.9 Polyglandular dysfunction, unspecified
0.516 0.484 0.000
E31.8 Other polyglandular dysfunction
0.516 0.484 0.000
E31.1 Polyglandular hyperfunction
0.516 0.484 0.000
T50.7 Analeptics and opioid receptor antagonists
0.000 0.485 0.515
T50.5 Appetite depressants
0.000 0.485 0.515
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.485 0.515
T50.1 Loop [high-ceiling] diuretics
0.000 0.485 0.515
T50.0 Mineralocorticoids and their antagonists
0.000 0.485 0.515
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.485 0.515
D03.3 Melanoma in situ of other and unspecified parts of face
0.515 0.485 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.000 0.492 0.508
E12.9 Without complications
0.507 0.493 0.000
E12.8 With unspecified complications
0.507 0.493 0.000
E12.7 With multiple complications
0.507 0.493 0.000
E12.6 With other specified complications
0.507 0.493 0.000
E12.5 With peripheral circulatory complications
0.507 0.493 0.000
E12.4 With neurological complications
0.507 0.493 0.000
E12.3 With ophthalmic complications
0.507 0.493 0.000
E12.2 With renal complications
0.507 0.493 0.000
E12.1 With ketoacidosis
0.507 0.493 0.000
E12.0 With coma
0.507 0.493 0.000
L71.9 Rosacea, unspecified
0.001 0.495 0.504
E20.8 Other hypoparathyroidism
0.503 0.497 0.000
E20.0 Idiopathic hypoparathyroidism
0.503 0.497 0.000
E10.3 With ophthalmic complications
0.500 0.500 0.000
E26 Hyperaldosteronism
0.496 0.504 0.000
J45.8 Mixed asthma
0.495 0.504 0.000
L68 Hypertrichosis
0.007 0.505 0.488
L70.9 Acne, unspecified
0.002 0.506 0.491
D00.2 Stomach
0.492 0.508 0.000
D00.1 Oesophagus
0.488 0.511 0.000
E30.9 Disorder of puberty, unspecified
0.487 0.512 0.000
E30.8 Other disorders of puberty
0.487 0.512 0.000
E30.1 Precocious puberty
0.487 0.512 0.000
E30.0 Delayed puberty
0.487 0.512 0.000
E32.9 Disease of thymus, unspecified
0.487 0.512 0.000
E32.8 Other diseases of thymus
0.487 0.512 0.000
E32.1 Abscess of thymus
0.487 0.512 0.000
E32.0 Persistent hyperplasia of thymus
0.487 0.512 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.487 0.512 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.487 0.512 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.487 0.512 0.000
T43.6 Psychostimulants with abuse potential
0.000 0.513 0.487
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.516 0.484
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.516 0.484
D00.0 Lip, oral cavity and pharynx
0.482 0.518 0.000
G36 Other acute disseminated demyelination
0.001 0.520 0.479
E44 Protein-energy malnutrition of moderate and mild degree
0.479 0.521 0.000
E45 Retarded development following protein-energy malnutrition
0.479 0.521 0.000
E43 Unspecified severe protein-energy malnutrition
0.479 0.521 0.000
E42 Marasmic kwashiorkor
0.479 0.521 0.000
E41 Nutritional marasmus
0.479 0.521 0.000
E40 Kwashiorkor
0.479 0.521 0.000
E23 Hypofunction and other disorders of pituitary gland
0.479 0.521 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.524 0.476
L75 Apocrine sweat disorders
0.007 0.525 0.468
L74 Eccrine sweat disorders
0.007 0.525 0.468
L67 Hair colour and hair shaft abnormalities
0.007 0.525 0.468
L64 Androgenic alopecia
0.007 0.525 0.468
L62 Nail disorders in diseases classified elsewhere
0.007 0.525 0.468
L63 Alopecia areata
0.007 0.528 0.465
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.532 0.468
E20.9 Hypoparathyroidism, unspecified
0.467 0.533 0.000
E25.9 Adrenogenital disorder, unspecified
0.466 0.533 0.000
E25.8 Other adrenogenital disorders
0.466 0.533 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.000 0.536 0.463
E27.9 Disorder of adrenal gland, unspecified
0.456 0.544 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.544 0.456
E06.5 Other chronic thyroiditis
0.456 0.544 0.000
D64.4 Congenital dyserythropoietic anaemia
0.454 0.546 0.000
D64.3 Other sideroblastic anaemias
0.454 0.546 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.454 0.546 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.454 0.546 0.000
D64.0 Hereditary sideroblastic anaemia
0.454 0.546 0.000
E07.8 Other specified disorders of thyroid
0.453 0.547 0.000
E06.4 Drug-induced thyroiditis
0.451 0.549 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.451 0.549 0.000
E06.1 Subacute thyroiditis
0.451 0.549 0.000
E06.0 Acute thyroiditis
0.451 0.549 0.000
L71.8 Other rosacea
0.002 0.549 0.449
L71.0 Perioral dermatitis
0.002 0.549 0.449
L40.8 Other psoriasis
0.012 0.550 0.438
E29.9 Testicular dysfunction, unspecified
0.443 0.557 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.559 0.441
D64.8 Other specified anaemias
0.439 0.561 0.000
E46 Unspecified protein-energy malnutrition
0.438 0.562 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.437 0.563 0.000
L70.8 Other acne
0.003 0.565 0.432
L70.5 Acne excoriee des jeunes filles
0.003 0.565 0.432
L70.4 Infantile acne
0.003 0.565 0.432
L70.3 Acne tropica
0.003 0.565 0.432
L70.2 Acne varioliformis
0.003 0.565 0.432
L70.1 Acne conglobata
0.003 0.565 0.432
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.565 0.435
L41 Parapsoriasis
0.115 0.568 0.316
L45 Papulosquamous disorders in diseases classified elsewhere
0.115 0.568 0.316
L40.2 Acrodermatitis continua
0.014 0.571 0.414
E06.3 Autoimmune thyroiditis
0.427 0.572 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.130 0.574 0.295
E23.2 Diabetes insipidus
0.425 0.575 0.000
E28.3 Primary ovarian failure
0.425 0.575 0.000
L40.1 Generalised pustular psoriasis
0.014 0.576 0.411
E22 Hyperfunction of pituitary gland
0.421 0.579 0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.416 0.584 0.000
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.416 0.584 0.000
N51.0 Disorders of prostate in diseases classified elsewhere
0.416 0.584 0.000
E29.8 Other testicular dysfunction
0.414 0.586 0.000
E29.0 Testicular hyperfunction
0.414 0.586 0.000
G37.5 Concentric sclerosis [Balo]
0.001 0.587 0.413
G37.4 Subacute necrotising myelitis
0.001 0.587 0.413
G37.2 Central pontine myelinolysis
0.001 0.587 0.413
G37.1 Central demyelination of corpus callosum
0.001 0.587 0.413
G37.0 Diffuse sclerosis
0.001 0.587 0.413
L44 Other papulosquamous disorders
0.125 0.589 0.287
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.591 0.409
E10.5 With peripheral circulatory complications
0.404 0.596 0.000
N49.9 Inflammatory disorder of unspecified male genital organ
0.404 0.596 0.000
N49.0 Inflammatory disorders of seminal vesicle
0.404 0.596 0.000
E28.9 Ovarian dysfunction, unspecified
0.404 0.596 0.000
E28.8 Other ovarian dysfunction
0.404 0.596 0.000
E28.1 Androgen excess
0.404 0.596 0.000
E28.0 Oestrogen excess
0.404 0.596 0.000
T48.5 Anti-common-cold drugs
0.000 0.597 0.403
D04.6 Skin of upper limb, including shoulder
0.402 0.598 0.000
N49.2 Inflammatory disorders of scrotum
0.400 0.600 0.000
T36.3 Macrolides
0.000 0.600 0.400
T37.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.600 0.400
L66 Cicatricial alopecia [scarring hair loss]
0.008 0.604 0.388
D60-D64 Aplastic and other anaemias
0.394 0.606 0.000
L65 Other nonscarring hair loss
0.007 0.606 0.387
L40.4 Guttate psoriasis
0.015 0.607 0.378
E34 Other endocrine disorders
0.389 0.610 0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.389 0.611 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.612 0.388
T37.5 Antiviral drugs
0.000 0.612 0.388
T37.4 Anthelminthics
0.000 0.612 0.388
T37.3 Other antiprotozoal drugs
0.000 0.612 0.388
T37.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.612 0.388
T37.1 Antimycobacterial drugs
0.000 0.612 0.388
T37.0 Sulphonamides
0.000 0.612 0.388
E06.9 Thyroiditis, unspecified
0.387 0.613 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.000 0.617 0.383
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.618 0.382
T48.4 Expectorants
0.000 0.618 0.382
T48.3 Antitussives
0.000 0.618 0.382
T48.2 Other and unspecified agents primarily acting on muscles
0.000 0.618 0.382
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.618 0.382
T48.0 Oxytocic drugs
0.000 0.618 0.382
T36.9 Systemic antibiotic, unspecified
0.000 0.618 0.381
T36.8 Other systemic antibiotics
0.000 0.618 0.381
T36.7 Antifungal antibiotics, systemically used
0.000 0.618 0.381
T36.6 Rifamycins
0.000 0.618 0.381
T36.5 Aminoglycosides
0.000 0.618 0.381
T36.4 Tetracyclines
0.000 0.618 0.381
T36.2 Chloramphenicol group
0.000 0.618 0.381
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.000 0.618 0.381
D09.0 Bladder
0.381 0.619 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.001 0.619 0.380
N43 Hydrocele and spermatocele
0.377 0.623 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.000 0.625 0.375
L68.0 Hirsutism
0.004 0.626 0.370
T39.0 Salicylates
0.000 0.630 0.370
L42 Pityriasis rosea
0.127 0.630 0.243
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.000 0.631 0.369
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.631 0.369
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.000 0.631 0.369
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.000 0.631 0.369
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.000 0.631 0.369
T44.1 Other parasympathomimetics [cholinergics]
0.000 0.631 0.369
T44.0 Anticholinesterase agents
0.000 0.631 0.369
N51.2 Balanitis in diseases classified elsewhere
0.368 0.631 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.632 0.368
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.637 0.363
G36.0 Neuromyelitis optica [Devic]
0.001 0.637 0.363
T36.0 Penicillins
0.000 0.637 0.363
N49.8 Inflammatory disorders of other specified male genital organs
0.361 0.638 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.000 0.638 0.361
T46.5 Other antihypertensive drugs, not elsewhere classified
0.000 0.639 0.361
K60.2 Anal fissure, unspecified
0.359 0.641 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.000 0.643 0.357
K60 Fissure and fistula of anal and rectal regions
0.357 0.643 0.000
E26.8 Other hyperaldosteronism
0.355 0.644 0.000
E26.1 Secondary hyperaldosteronism
0.355 0.644 0.000
L68.9 Hypertrichosis, unspecified
0.005 0.645 0.350
L68.8 Other hypertrichosis
0.005 0.645 0.350
L68.3 Polytrichia
0.005 0.645 0.350
L68.2 Localised hypertrichosis
0.005 0.645 0.350
L68.1 Acquired hypertrichosis lanuginosa
0.005 0.645 0.350
L40.3 Pustulosis palmaris et plantaris
0.016 0.647 0.337
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.648 0.352
T41.5 Therapeutic gases
0.000 0.652 0.347
T41.4 Anaesthetic, unspecified
0.000 0.652 0.347
T41.3 Local anaesthetics
0.000 0.652 0.347
T41.1 Intravenous anaesthetics
0.000 0.652 0.347
T41.0 Inhaled anaesthetics
0.000 0.652 0.347
E50-E64 Other nutritional deficiencies
0.347 0.652 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.653 0.347
T46.8 Antivaricose drugs, including sclerosing agents
0.000 0.653 0.347
T46.7 Peripheral vasodilators
0.000 0.653 0.347
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.653 0.347
G36.9 Acute disseminated demyelination, unspecified
0.001 0.655 0.344
G36.8 Other specified acute disseminated demyelination
0.001 0.655 0.344
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.001 0.655 0.344
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.655 0.344
E44.1 Mild protein-energy malnutrition
0.343 0.656 0.000
E44.0 Moderate protein-energy malnutrition
0.343 0.656 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.343 0.656 0.000
E23.1 Drug-induced hypopituitarism
0.343 0.656 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.343 0.657 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.000 0.657 0.342
T38.1 Thyroid hormones and substitutes
0.000 0.658 0.341
T49.9 Topical agent, unspecified
0.000 0.659 0.341
T49.8 Other topical agents
0.000 0.659 0.341
T49.7 Dental drugs, topically applied
0.000 0.659 0.341
T49.6 Otorhinolaryngological drugs and preparations
0.000 0.659 0.341
T49.5 Ophthalmological drugs and preparations
0.000 0.659 0.341
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.659 0.341
T49.3 Emollients, demulcents and protectants
0.000 0.659 0.341
T49.2 Local astringents and local detergents
0.000 0.659 0.341
T49.1 Antipruritics
0.000 0.659 0.341
L62.8 Nail disorders in other diseases classified elsewhere
0.005 0.659 0.336
L62.0 Clubbed nail pachydermoperiostosis
0.005 0.659 0.336
L64.9 Androgenic alopecia, unspecified
0.005 0.659 0.336
L64.8 Other androgenic alopecia
0.005 0.659 0.336
L64.0 Drug-induced androgenic alopecia
0.005 0.659 0.336
L67.9 Hair colour and hair shaft abnormality, unspecified
0.005 0.659 0.336
L67.8 Other hair colour and hair shaft abnormalities
0.005 0.659 0.336
L67.1 Variations in hair colour
0.005 0.659 0.336
L67.0 Trichorrhexis nodosa
0.005 0.659 0.336
L74.9 Eccrine sweat disorder, unspecified
0.005 0.659 0.336
L74.8 Other eccrine sweat disorders
0.005 0.659 0.336
L74.4 Anhidrosis
0.005 0.659 0.336
L74.3 Miliaria, unspecified
0.005 0.659 0.336
L74.2 Miliaria profunda
0.005 0.659 0.336
L74.1 Miliaria crystallina
0.005 0.659 0.336
L74.0 Miliaria rubra
0.005 0.659 0.336
L75.9 Apocrine sweat disorder, unspecified
0.005 0.659 0.336
L75.8 Other apocrine sweat disorders
0.005 0.659 0.336
L75.2 Apocrine miliaria
0.005 0.659 0.336
L75.1 Chromhidrosis
0.005 0.659 0.336
L75.0 Bromhidrosis
0.005 0.659 0.336
T47.0 Histamine H(2)-receptor antagonists
0.000 0.660 0.340
L63.8 Other alopecia areata
0.005 0.662 0.333
L63.2 Ophiasis
0.005 0.662 0.333
L63.1 Alopecia universalis
0.005 0.662 0.333
L63.0 Alopecia (capitis) totalis
0.005 0.662 0.333
K60.5 Anorectal fistula
0.336 0.664 0.000
L63.9 Alopecia areata, unspecified
0.005 0.665 0.330
T47.2 Stimulant laxatives
0.000 0.670 0.330
K60.3 Anal fistula
0.329 0.671 0.000
K60.0 Acute anal fissure
0.328 0.672 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.000 0.673 0.327
T47.8 Other agents primarily affecting the gastro-intestinal system
0.000 0.673 0.327
T47.7 Emetics
0.000 0.673 0.327
T47.5 Digestants
0.000 0.673 0.327

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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