TreeWAS – Variant ID: rs9275596

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
K90.0 Coeliac disease	1.000	0.000	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
G35 Multiple sclerosis	1.000	0.000	0.000
M06 Other rheumatoid arthritis	0.000	0.000	1.000
R31 Unspecified haematuria	0.000	0.000	1.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
J45.9 Asthma, unspecified	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	0.000	0.000	1.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.000	1.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.001	0.999
M05-M14 Inflammatory polyarthropathies	0.000	0.001	0.999
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.001	0.999
L40 Psoriasis	0.000	0.003	0.997
M06.3 Rheumatoid nodule	0.000	0.005	0.995
M06.0 Seronegative rheumatoid arthritis	0.000	0.006	0.994
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.006	0.994
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.006	0.994
L40.5 Arthropathic psoriasis	0.000	0.007	0.993
E78.0 Pure hypercholesterolaemia	0.000	0.008	0.992
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.009	0.991
J33.9 Nasal polyp, unspecified	0.000	0.009	0.991
K90 Intestinal malabsorption	0.988	0.012	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.982	0.018	0.000
E05.9 Thyrotoxicosis, unspecified	0.980	0.020	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.021	0.979
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.031	0.969
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.967	0.033	0.000
K90.9 Intestinal malabsorption, unspecified	0.967	0.033	0.000
D69 Purpura and other haemorrhagic conditions	0.966	0.034	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.035	0.965
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.954	0.046	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.046	0.954
D69.6 Thrombocytopenia, unspecified	0.953	0.047	0.000
D68 Other coagulation defects	0.950	0.050	0.000
M07 Psoriatic and enteropathic arthropathies	0.000	0.051	0.949
M06.34 Rheumatoid nodule (Hand)	0.000	0.051	0.949
D80-D89 Certain disorders involving the immune mechanism	0.948	0.052	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.947	0.053	0.000
D86 Sarcoidosis	0.930	0.070	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.076	0.924
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.076	0.924
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.920	0.080	0.000
D86.9 Sarcoidosis, unspecified	0.920	0.080	0.000
M07.3 Other psoriatic arthropathies	0.000	0.081	0.919
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.092	0.908
D50-D53 Nutritional anaemias	0.899	0.101	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.102	0.898
D69.3 Idiopathic thrombocytopenic purpura	0.890	0.110	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.112	0.888
C82.0 Small cleaved cell, follicular	0.000	0.113	0.887
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.115	0.885
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.117	0.883
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.118	0.882
M45 Ankylosing spondylitis	0.000	0.122	0.878
J33 Nasal polyp	0.000	0.126	0.874
D69.4 Other primary thrombocytopenia	0.867	0.133	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.143	0.857
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.152	0.848
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.154	0.846
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.154	0.846
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.842	0.158	0.000
D68.5 Primary Thrombophilia	0.841	0.159	0.000
D68.9 Coagulation defect, unspecified	0.833	0.167	0.000
D52 Folate deficiency anaemia	0.832	0.168	0.000
J33.0 Polyp of nasal cavity	0.000	0.170	0.830
D89.2 Hypergammaglobulinaemia, unspecified	0.829	0.171	0.000
C82.3 Follicular lymphoma grade IIIa	0.000	0.174	0.826
D89.9 Disorder involving the immune mechanism, unspecified	0.825	0.175	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.000	0.177	0.823
N48 Other disorders of penis	0.000	0.183	0.817
D51 Vitamin B12 deficiency anaemia	0.816	0.184	0.000
L40.8 Other psoriasis	0.000	0.187	0.813
M06.4 Inflammatory polyarthropathy	0.000	0.188	0.812
D68.0 Von Willebrand's disease	0.811	0.189	0.000
D69.8 Other specified haemorrhagic conditions	0.808	0.192	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.195	0.805
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.197	0.803
C21.1 Anal canal	0.000	0.200	0.800
D68.6 Other Thrombophilia	0.799	0.201	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.201	0.799
D68.8 Other specified coagulation defects	0.798	0.202	0.000
C21.0 Anus, unspecified	0.000	0.206	0.794
C21 Malignant neoplasm of anus and anal canal	0.000	0.208	0.792
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.211	0.789
D55-D59 Haemolytic anaemias	0.787	0.213	0.000
C82.2 Large cell, follicular	0.000	0.213	0.787
D52.9 Folate deficiency anaemia, unspecified	0.785	0.215	0.000
C34 Malignant neoplasm of bronchus and lung	0.782	0.218	0.000
N48.6 Balanitis xerotica obliterans	0.000	0.219	0.781
L40.1 Generalised pustular psoriasis	0.000	0.221	0.779
C34.9 Bronchus or lung, unspecified	0.776	0.224	0.000
N48.0 Leukoplakia of penis	0.000	0.226	0.774
N48.2 Other inflammatory disorders of penis	0.000	0.227	0.773
L40.0 Psoriasis vulgaris	0.000	0.231	0.769
C34.3 Lower lobe, bronchus or lung	0.768	0.232	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.768	0.232	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.767	0.233	0.000
N40-N51 Diseases of male genital organs	0.000	0.236	0.764
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.750	0.250	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.255	0.745
M05.2 Rheumatoid vasculitis	0.000	0.258	0.742
D69.5 Secondary thrombocytopenia	0.740	0.260	0.000
K90.8 Other intestinal malabsorption	0.733	0.267	0.000
C82.4 Follicular lymphoma grade IIIb	0.000	0.268	0.732
M06.8 Other specified rheumatoid arthritis	0.000	0.271	0.728
D67 Hereditary factor IX deficiency	0.728	0.272	0.000
C34.1 Upper lobe, bronchus or lung	0.723	0.277	0.000
N48.5 Ulcer of penis	0.000	0.279	0.721
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.280	0.720
G37 Other demyelinating diseases of central nervous system	0.720	0.280	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.283	0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.283	0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.283	0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.283	0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.283	0.717
M06.2 Rheumatoid bursitis	0.000	0.283	0.717
M06.1 Adult-onset Still's disease	0.000	0.283	0.717
M05.8 Other seropositive rheumatoid arthritis	0.000	0.283	0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.283	0.717
M05.1 Rheumatoid lung disease	0.000	0.283	0.717
M05.0 Felty's syndrome	0.000	0.283	0.717
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.283	0.716
M08 Juvenile arthritis	0.000	0.283	0.716
L40.4 Guttate psoriasis	0.000	0.285	0.715
L40.2 Acrodermatitis continua	0.000	0.285	0.715
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.286	0.714
M06.38 Rheumatoid nodule (Other)	0.000	0.286	0.714
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.286	0.714
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.286	0.714
M06.33 Rheumatoid nodule (Forearm)	0.000	0.286	0.714
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.286	0.714
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.287	0.713
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.287	0.713
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.287	0.713
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.287	0.713
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.287	0.713
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.288	0.712
C34.2 Middle lobe, bronchus or lung	0.710	0.290	0.000
K90.3 Pancreatic steatorrhoea	0.708	0.292	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.708	0.292	0.000
K90.1 Tropical sprue	0.708	0.292	0.000
C34.0 Main bronchus	0.707	0.293	0.000
D86.3 Sarcoidosis of skin	0.706	0.294	0.000
J33.8 Other polyp of sinus	0.000	0.296	0.704
E05.5 Thyroid crisis or storm	0.704	0.296	0.000
E05.4 Thyrotoxicosis factitia	0.704	0.296	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.704	0.296	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.704	0.296	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.703	0.297	0.000
N48.8 Other specified disorders of penis	0.000	0.299	0.701
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.299	0.700
D59 Acquired haemolytic anaemia	0.700	0.300	0.000
M11 Other crystal arthropathies	0.000	0.303	0.697
C82.6 Cutaneous follicle centre lymphoma	0.000	0.305	0.695
C82.5 Diffuse follicle centre lymphoma	0.000	0.305	0.695
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.694	0.306	0.000
M12 Other specific arthropathies	0.000	0.309	0.691
D89.1 Cryoglobulinaemia	0.691	0.309	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.315	0.685
N48.1 Balanoposthitis	0.000	0.317	0.683
M14 Arthropathies in other diseases classified elsewhere	0.000	0.318	0.682
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.318	0.682
M07.5 Arthropathy in ulcerative colitis	0.000	0.319	0.681
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.000	0.319	0.681
M07.2 Psoriatic spondylitis	0.000	0.319	0.681
M07.1 Arthritis mutilans	0.000	0.319	0.681
M07.0 Distal interphalangeal psoriatic arthropathy	0.000	0.319	0.681
D81 Combined immunodeficiencies	0.680	0.320	0.000
N48.9 Disorder of penis, unspecified	0.000	0.327	0.673
L40.3 Pustulosis palmaris et plantaris	0.000	0.335	0.665
D68.2 Hereditary deficiency of other clotting factors	0.662	0.338	0.000
D69.2 Other nonthrombocytopenic purpura	0.660	0.340	0.000
D89.3 Immune reconstitution syndrome	0.660	0.340	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.341	0.659
D86.0 Sarcoidosis of lung	0.659	0.341	0.000
M07.38 Other psoriatic arthropathies (Other)	0.000	0.341	0.659
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.341	0.659
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.341	0.659
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.341	0.659
D82 Immunodeficiency associated with other major defects	0.658	0.342	0.000
D69.1 Qualitative platelet defects	0.658	0.342	0.000
D86.1 Sarcoidosis of lymph nodes	0.657	0.343	0.000
D83 Common variable immunodeficiency	0.653	0.347	0.000
D84 Other immunodeficiencies	0.644	0.355	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.000	0.358	0.642
G37.9 Demyelinating disease of central nervous system, unspecified	0.641	0.359	0.000
M07.6 Other enteropathic arthropathies	0.000	0.364	0.636
J33.1 Polypoid sinus degeneration	0.000	0.365	0.635
D59.1 Other autoimmune haemolytic anaemias	0.633	0.367	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.368	0.632
D69.0 Allergic purpura	0.631	0.369	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.371	0.629
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.371	0.629
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.371	0.629
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.371	0.629
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.371	0.629
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.371	0.629
D53 Other nutritional anaemias	0.625	0.375	0.000
D68.4 Acquired coagulation factor deficiency	0.624	0.376	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.623	0.376	0.000
C34.8 Overlapping lesion of bronchus and lung	0.622	0.377	0.000
L40-L45 Papulosquamous disorders	0.001	0.382	0.617
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.616	0.384	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.384	0.616
D51.8 Other vitamin B12 deficiency anaemias	0.599	0.401	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.599	0.401	0.000
D52.8 Other folate deficiency anaemias	0.597	0.403	0.000
D52.1 Drug-induced folate deficiency anaemia	0.597	0.403	0.000
D52.0 Dietary folate deficiency anaemia	0.597	0.403	0.000
D68.1 Hereditary factor XI deficiency	0.595	0.404	0.000
N48.3 Priapism	0.000	0.409	0.591
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.410	0.590
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.412	0.588
D51.3 Other dietary vitamin B12 deficiency anaemia	0.585	0.415	0.000
D51.2 Transcobalamin II deficiency	0.585	0.415	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.585	0.415	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.417	0.582
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.417	0.582
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.417	0.582
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.417	0.582
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.417	0.582
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.417	0.582
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.417	0.582
M35.0 Sicca syndrome [Sjogren]	0.578	0.422	0.000
N51 Disorders of male genital organs in diseases classified elsewhere	0.000	0.423	0.577
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.426	0.574
D60-D64 Aplastic and other anaemias	0.573	0.427	0.000
E05.8 Other thyrotoxicosis	0.572	0.428	0.001
C21.2 Cloacogenic zone	0.000	0.432	0.568
N44 Torsion of testis	0.000	0.434	0.566
D58 Other hereditary haemolytic anaemias	0.565	0.435	0.000
D55 Anaemia due to enzyme disorders	0.564	0.436	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.000	0.442	0.557
M14.6 Neuropathic arthropathy	0.000	0.446	0.554
N48.4 Impotence of organic origin	0.000	0.453	0.547
D57 Sickle-cell disorders	0.546	0.453	0.000
G36 Other acute disseminated demyelination	0.545	0.454	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.538	0.461	0.000
D80 Immunodeficiency with predominantly antibody defects	0.533	0.467	0.000
M05.28 Rheumatoid vasculitis (Other)	0.000	0.468	0.532
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.000	0.468	0.532
M05.26 Rheumatoid vasculitis (Lower leg)	0.000	0.468	0.532
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.000	0.468	0.532
M05.24 Rheumatoid vasculitis (Hand)	0.000	0.468	0.532
M05.23 Rheumatoid vasculitis (Forearm)	0.000	0.468	0.532
M05.22 Rheumatoid vasculitis (Upper arm)	0.000	0.468	0.532
M05.21 Rheumatoid vasculitis (Shoulder region)	0.000	0.468	0.532
M05.20 Rheumatoid vasculitis (Multiple sites)	0.000	0.468	0.532
N42 Other disorders of prostate	0.000	0.469	0.531
N49.2 Inflammatory disorders of scrotum	0.000	0.470	0.529
D69.9 Haemorrhagic condition, unspecified	0.529	0.471	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.472	0.528
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.472	0.528
D66 Hereditary factor VIII deficiency	0.524	0.476	0.000
L42 Pityriasis rosea	0.000	0.476	0.523
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.477	0.522
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.477	0.522
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.477	0.522
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.477	0.522
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.477	0.522
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.477	0.522
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.477	0.522
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.477	0.522
D59.9 Acquired haemolytic anaemia, unspecified	0.521	0.479	0.000
G37.5 Concentric sclerosis [Balo]	0.516	0.484	0.000
G37.4 Subacute necrotising myelitis	0.516	0.484	0.000
G37.2 Central pontine myelinolysis	0.516	0.484	0.000
G37.1 Central demyelination of corpus callosum	0.516	0.484	0.000
G37.0 Diffuse sclerosis	0.516	0.484	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.484	0.516
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.486	0.514
M06.18 Adult-onset Still's disease (Other)	0.000	0.486	0.514
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.486	0.514
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.486	0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.486	0.514
M06.14 Adult-onset Still's disease (Hand)	0.000	0.486	0.514
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.486	0.514
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.486	0.514
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.486	0.514
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.486	0.514
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.486	0.514
M06.28 Rheumatoid bursitis (Other)	0.000	0.486	0.514
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.486	0.514
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.486	0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.486	0.514
M06.24 Rheumatoid bursitis (Hand)	0.000	0.486	0.514
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.486	0.514
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.486	0.514
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.486	0.514
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.486	0.514
M05.09 Felty's syndrome (Site unspecified)	0.000	0.486	0.514
M05.08 Felty's syndrome (Other)	0.000	0.486	0.514
M05.07 Felty's syndrome (Ankle and foot)	0.000	0.486	0.514
M05.06 Felty's syndrome (Lower leg)	0.000	0.486	0.514
M05.05 Felty's syndrome (Pelvic region and thigh)	0.000	0.486	0.514
M05.04 Felty's syndrome (Hand)	0.000	0.486	0.514
M05.03 Felty's syndrome (Forearm)	0.000	0.486	0.514
M05.02 Felty's syndrome (Upper arm)	0.000	0.486	0.514
M05.01 Felty's syndrome (Shoulder region)	0.000	0.486	0.514
M05.00 Felty's syndrome (Multiple sites)	0.000	0.486	0.514
M05.19 Rheumatoid lung disease (Site unspecified)	0.000	0.486	0.514
M05.18 Rheumatoid lung disease (Other)	0.000	0.486	0.514
M05.17 Rheumatoid lung disease (Ankle and foot)	0.000	0.486	0.514
M05.16 Rheumatoid lung disease (Lower leg)	0.000	0.486	0.514
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.000	0.486	0.514
M05.14 Rheumatoid lung disease (Hand)	0.000	0.486	0.514
M05.13 Rheumatoid lung disease (Forearm)	0.000	0.486	0.514
M05.12 Rheumatoid lung disease (Upper arm)	0.000	0.486	0.514
M05.11 Rheumatoid lung disease (Shoulder region)	0.000	0.486	0.514
M05.10 Rheumatoid lung disease (Multiple sites)	0.000	0.486	0.514
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.000	0.486	0.514
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.000	0.486	0.514
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.000	0.486	0.514
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.000	0.486	0.514
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.000	0.486	0.514
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.000	0.486	0.514
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.000	0.486	0.514
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.000	0.486	0.514
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.000	0.486	0.514
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.000	0.486	0.514
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.000	0.486	0.514
M05.88 Other seropositive rheumatoid arthritis (Other)	0.000	0.486	0.514
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.000	0.486	0.514
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.000	0.486	0.514
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.000	0.486	0.514
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.000	0.486	0.514
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.000	0.486	0.514
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.000	0.486	0.514
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.000	0.486	0.514
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.486	0.514
M08.9 Juvenile arthritis, unspecified	0.000	0.486	0.514
M08.8 Other juvenile arthritis	0.000	0.486	0.514
M08.4 Pauciarticular juvenile arthritis	0.000	0.486	0.514
M08.3 Juvenile polyarthritis (seronegative)	0.000	0.486	0.514
M08.2 Juvenile arthritis with systemic onset	0.000	0.486	0.514
M08.1 Juvenile ankylosing spondylitis	0.000	0.486	0.514
M08.0 Juvenile rheumatoid arthritis	0.000	0.486	0.514
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.000	0.486	0.514
M09.2 Juvenile arthritis in ulcerative colitis	0.000	0.486	0.514
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.000	0.486	0.514
M09.0 Juvenile arthritis in psoriasis	0.000	0.486	0.514
M12.3 Palindromic rheumatism	0.000	0.487	0.513
M11.9 Crystal arthropathy, unspecified	0.000	0.492	0.507
D84.1 Defects in the complement system	0.507	0.493	0.000
D56 Thalassaemia	0.504	0.496	0.000
D59.8 Other acquired haemolytic anaemias	0.502	0.498	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.502	0.498	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.502	0.498	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.502	0.498	0.000
D59.3 Haemolytic-uraemic syndrome	0.502	0.498	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.502	0.498	0.000
N49.8 Inflammatory disorders of other specified male genital organs	0.000	0.500	0.500
M11.1 Familial chondrocalcinosis	0.000	0.500	0.500
M11.0 Hydroxyapatite deposition disease	0.000	0.500	0.500
M12.5 Traumatic arthropathy	0.000	0.504	0.496
M12.4 Intermittent hydrarthrosis	0.000	0.504	0.496
M12.1 Kaschin-Beck disease	0.000	0.504	0.496
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.000	0.504	0.496
D59.0 Drug-induced autoimmune haemolytic anaemia	0.495	0.504	0.000
M11.2 Other chondrocalcinosis	0.000	0.505	0.495
D86.8 Sarcoidosis of other and combined sites	0.494	0.506	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.000	0.511	0.489
M14.4 Arthropathy in amyloidosis	0.000	0.511	0.489
M14.3 Lipoid dermatoarthritis	0.000	0.511	0.489
M14.1 Crystal arthropathy in other metabolic disorders	0.000	0.511	0.489
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.000	0.511	0.489
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.000	0.512	0.488
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.000	0.512	0.488
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.000	0.512	0.488
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.000	0.512	0.488
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.000	0.512	0.488
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.000	0.512	0.488
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.000	0.512	0.488
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.000	0.512	0.488
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.000	0.512	0.488
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.000	0.512	0.488
M07.19 Arthritis mutilans (Site unspecified)	0.000	0.512	0.488
M07.18 Arthritis mutilans (Other)	0.000	0.512	0.488
M07.17 Arthritis mutilans (Ankle and foot)	0.000	0.512	0.488
M07.16 Arthritis mutilans (Lower leg)	0.000	0.512	0.488
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.000	0.512	0.488
M07.14 Arthritis mutilans (Hand)	0.000	0.512	0.488
M07.13 Arthritis mutilans (Forearm)	0.000	0.512	0.488
M07.12 Arthritis mutilans (Upper arm)	0.000	0.512	0.488
M07.11 Arthritis mutilans (Shoulder region)	0.000	0.512	0.488
M07.10 Arthritis mutilans (Multiple sites)	0.000	0.512	0.488
M07.29 Psoriatic spondylitis (Site unspecified)	0.000	0.512	0.488
M07.28 Psoriatic spondylitis (Other)	0.000	0.512	0.488
M07.27 Psoriatic spondylitis (Ankle and foot)	0.000	0.512	0.488
M07.26 Psoriatic spondylitis (Lower leg)	0.000	0.512	0.488
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.000	0.512	0.488
M07.24 Psoriatic spondylitis (Hand)	0.000	0.512	0.488
M07.23 Psoriatic spondylitis (Forearm)	0.000	0.512	0.488
M07.22 Psoriatic spondylitis (Upper arm)	0.000	0.512	0.488
M07.21 Psoriatic spondylitis (Shoulder region)	0.000	0.512	0.488
M07.20 Psoriatic spondylitis (Multiple sites)	0.000	0.512	0.488
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.000	0.512	0.488
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.000	0.512	0.488
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.000	0.512	0.488
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.000	0.512	0.488
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.000	0.512	0.488
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.000	0.512	0.488
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.000	0.512	0.488
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.000	0.512	0.488
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.000	0.512	0.488
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.000	0.512	0.488
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.000	0.512	0.488
M07.58 Arthropathy in ulcerative colitis (Other)	0.000	0.512	0.488
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.000	0.512	0.488
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.000	0.512	0.488
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.000	0.512	0.488
M07.54 Arthropathy in ulcerative colitis (Hand)	0.000	0.512	0.488
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.000	0.512	0.488
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.000	0.512	0.488
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.000	0.512	0.488
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.000	0.512	0.488
D81.9 Combined immunodeficiency, unspecified	0.487	0.512	0.000
D81.8 Other combined immunodeficiencies	0.487	0.512	0.000
D81.7 Major histocompatibility complex class II deficiency	0.487	0.512	0.000
D81.6 Major histocompatibility complex class I deficiency	0.487	0.512	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.487	0.512	0.000
D81.4 Nezelof's syndrome	0.487	0.512	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.487	0.512	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.487	0.512	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.487	0.512	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.487	0.512	0.000
D61 Other aplastic anaemias	0.488	0.512	0.000
M11.8 Other specified crystal arthropathies	0.000	0.522	0.478
M12.2 Villonodular synovitis (pigmented)	0.000	0.525	0.475
L43 Lichen planus	0.000	0.526	0.473
M14.2 Diabetic arthropathy	0.000	0.527	0.473
D82.9 Immunodeficiency associated with major defect, unspecified	0.472	0.528	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.472	0.528	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.472	0.528	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.472	0.528	0.000
D82.2 Immunodeficiency with short-limbed stature	0.472	0.528	0.000
D82.0 Wiskott-Aldrich syndrome	0.472	0.528	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.471	0.528	0.001
M12.8 Other specific arthropathies, not elsewhere classified	0.000	0.528	0.472
D50 Iron deficiency anaemia	0.468	0.532	0.000
D83.8 Other common variable immunodeficiencies	0.468	0.532	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.468	0.532	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.468	0.532	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.468	0.532	0.000
D84.8 Other specified immunodeficiencies	0.468	0.532	0.000
N42.2 Atrophy of prostate	0.000	0.534	0.466
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.462	0.538	0.000
N49.9 Inflammatory disorder of unspecified male genital organ	0.000	0.540	0.460
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.000	0.540	0.460
N49.0 Inflammatory disorders of seminal vesicle	0.000	0.540	0.460
E03 Other hypothyroidism	0.222	0.541	0.238
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.459	0.541	0.000
M07.68 Other enteropathic arthropathies (Other)	0.000	0.544	0.456
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.000	0.544	0.456
M07.66 Other enteropathic arthropathies (Lower leg)	0.000	0.544	0.456
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.000	0.544	0.456
M07.64 Other enteropathic arthropathies (Hand)	0.000	0.544	0.456
M07.63 Other enteropathic arthropathies (Forearm)	0.000	0.544	0.456
M07.62 Other enteropathic arthropathies (Upper arm)	0.000	0.544	0.456
M07.61 Other enteropathic arthropathies (Shoulder region)	0.000	0.544	0.456
M07.60 Other enteropathic arthropathies (Multiple sites)	0.000	0.544	0.456
D82.1 Di George's syndrome	0.450	0.550	0.000
D53.8 Other specified nutritional anaemias	0.448	0.552	0.000
D53.2 Scorbutic anaemia	0.448	0.552	0.000
D53.0 Protein deficiency anaemia	0.448	0.552	0.000
D61.9 Aplastic anaemia, unspecified	0.443	0.557	0.000
L41 Parapsoriasis	0.001	0.557	0.442
L45 Papulosquamous disorders in diseases classified elsewhere	0.001	0.557	0.442
L44 Other papulosquamous disorders	0.001	0.558	0.442
N51.2 Balanitis in diseases classified elsewhere	0.000	0.558	0.442
D83.9 Common variable immunodeficiency, unspecified	0.441	0.559	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.428	0.571	0.000
D53.9 Nutritional anaemia, unspecified	0.417	0.583	0.000
M13 Other arthritis	0.000	0.586	0.414
N51.8 Other disorders of male genital organs in diseases classified elsewhere	0.000	0.586	0.413
N51.1 Disorders of testis and epididymis in diseases classified elsewhere	0.000	0.586	0.413
N51.0 Disorders of prostate in diseases classified elsewhere	0.000	0.586	0.413
M07.69 Other enteropathic arthropathies (Site unspecified)	0.000	0.588	0.411
D62 Acute posthaemorrhagic anaemia	0.410	0.590	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.408	0.592	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.593	0.407
E00-E07 Disorders of thyroid gland	0.368	0.594	0.037
D58.8 Other specified hereditary haemolytic anaemias	0.405	0.595	0.000
D58.2 Other haemoglobinopathies	0.405	0.595	0.000
D58.1 Hereditary elliptocytosis	0.405	0.595	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.405	0.595	0.000
D55.8 Other anaemias due to enzyme disorders	0.405	0.595	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.405	0.595	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.405	0.595	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.405	0.595	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.405	0.595	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.404	0.596	0.000
M12.30 Palindromic rheumatism (Multiple sites)	0.000	0.597	0.403
D57.8 Other sickle-cell disorders	0.392	0.608	0.000
D57.3 Sickle-cell trait	0.392	0.608	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations