TreeWAS – Variant ID: rs9275601

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.9 Without complications	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
H36.0 Diabetic retinopathy	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
N00-N08 Glomerular diseases	1.000	0.000	0.000
H30-H36 Disorders of choroid and retina	1.000	0.000	0.000
E10.1 With ketoacidosis	1.000	0.000	0.000
H36 Retinal disorders in diseases classified elsewhere	1.000	0.000	0.000
E14 Unspecified diabetes mellitus	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
N08 Glomerular disorders in diseases classified elsewhere	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E11 Non-insulin-dependent diabetes mellitus	1.000	0.000	0.000
N08.3 Glomerular disorders in diabetes mellitus	1.000	0.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
D64.9 Anaemia, unspecified	1.000	0.000	0.000
K90 Intestinal malabsorption	1.000	0.000	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E16.2 Hypoglycaemia, unspecified	0.999	0.001	0.000
E16 Other disorders of pancreatic internal secretion	0.999	0.001	0.000
E14.3 With ophthalmic complications	0.999	0.001	0.000
E10.4 With neurological complications	0.999	0.001	0.000
D64 Other anaemias	0.999	0.001	0.000
D60-D64 Aplastic and other anaemias	0.999	0.001	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.001	0.999
E00-E07 Disorders of thyroid gland	0.999	0.001	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.002	0.998
M06 Other rheumatoid arthritis	0.000	0.002	0.998
E10.2 With renal complications	0.997	0.003	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.003	0.997
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.004	0.996
Chapter XIV Diseases of the genitourinary system	0.995	0.005	0.000
G35 Multiple sclerosis	0.000	0.005	0.995
N17-N19 Renal failure	0.994	0.006	0.000
K90.9 Intestinal malabsorption, unspecified	0.992	0.008	0.000
N04 Nephrotic syndrome	0.992	0.008	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.011	0.989
N05 Unspecified nephritic syndrome	0.989	0.011	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.984	0.016	0.000
M05-M14 Inflammatory polyarthropathies	0.000	0.019	0.981
N17 Acute renal failure	0.979	0.021	0.000
E11.2 With renal complications	0.979	0.021	0.000
N04.9 Unspecified	0.979	0.021	0.000
N18 Chronic renal failure	0.978	0.022	0.000
K90-K93 Other diseases of the digestive system	0.976	0.024	0.000
E10.5 With peripheral circulatory complications	0.975	0.025	0.000
N17.9 Acute renal failure, unspecified	0.974	0.026	0.000
Chapter XI Diseases of the digestive system	0.974	0.026	0.000
K70-K77 Diseases of liver	0.974	0.026	0.000
K70 Alcoholic liver disease	0.971	0.029	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.032	0.968
E40-E46 Malnutrition	0.968	0.032	0.000
K70.9 Alcoholic liver disease, unspecified	0.959	0.041	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.958	0.042	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.007	0.047	0.946
H34 Retinal vascular occlusions	0.951	0.049	0.000
E10.8 With unspecified complications	0.947	0.053	0.000
E46 Unspecified protein-energy malnutrition	0.944	0.056	0.000
H52 Disorders of refraction and accommodation	0.944	0.056	0.000
H35 Other retinal disorders	0.942	0.058	0.000
E11.0 With coma	0.939	0.061	0.000
N18.9 Chronic renal failure, unspecified	0.935	0.065	0.000
G37 Other demyelinating diseases of central nervous system	0.001	0.067	0.932
D80-D89 Certain disorders involving the immune mechanism	0.929	0.071	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.072	0.928
N05.1 Focal and segmental glomerular lesions	0.927	0.073	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.077	0.923
K72 Hepatic failure, not elsewhere classified	0.923	0.077	0.000
E11.6 With other specified complications	0.921	0.079	0.000
M06.3 Rheumatoid nodule	0.000	0.083	0.917
N18.5 Chronic kidney disease, stage 5	0.916	0.084	0.000
E11.5 With peripheral circulatory complications	0.911	0.089	0.000
H43-H45 Disorders of vitreous body and globe	0.908	0.092	0.000
H52.2 Astigmatism	0.902	0.098	0.000
H52.3 Anisometropia and aniseikonia	0.899	0.101	0.000
D70 Agranulocytosis	0.898	0.102	0.000
H50 Other strabismus	0.897	0.103	0.000
E10.0 With coma	0.893	0.107	0.000
E14.8 With unspecified complications	0.893	0.107	0.000
Chapter IX Diseases of the circulatory system	0.889	0.111	0.000
K70.3 Alcoholic cirrhosis of liver	0.888	0.112	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.112	0.887
H35.0 Background retinopathy and retinal vascular changes	0.887	0.113	0.000
D80 Immunodeficiency with predominantly antibody defects	0.884	0.116	0.000
H43 Disorders of vitreous body	0.880	0.120	0.000
N18.0 End-stage renal disease	0.879	0.121	0.000
H35.2 Other proliferative retinopathy	0.879	0.121	0.000
D75 Other diseases of blood and blood-forming organs	0.874	0.126	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.868	0.132	0.000
H53-H54 Visual disturbances and blindness	0.867	0.133	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.866	0.134	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.134	0.866
I10-I15 Hypertensive diseases	0.865	0.135	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.136	0.864
E11.9 Without complications	0.864	0.136	0.000
H34.8 Other retinal vascular occlusions	0.861	0.139	0.000
K72.9 Hepatic failure, unspecified	0.858	0.142	0.000
H50.9 Strabismus, unspecified	0.857	0.143	0.000
K74 Fibrosis and cirrhosis of liver	0.855	0.145	0.000
E14.5 With peripheral circulatory complications	0.853	0.147	0.000
N05.9 Unspecified	0.852	0.148	0.000
H43.1 Vitreous haemorrhage	0.845	0.155	0.000
I12 Hypertensive renal disease	0.844	0.156	0.000
N04.1 Focal and segmental glomerular lesions	0.841	0.159	0.000
I05-I09 Chronic rheumatic heart diseases	0.834	0.166	0.000
I07.1 Tricuspid insufficiency	0.834	0.166	0.000
I07 Rheumatic tricuspid valve diseases	0.833	0.167	0.000
E11.3 With ophthalmic complications	0.833	0.167	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.821	0.178	0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.820	0.180	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.180	0.820
K70.1 Alcoholic hepatitis	0.819	0.181	0.000
H05 Disorders of orbit	0.819	0.181	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.001	0.182	0.818
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.817	0.183	0.000
H54 Blindness and low vision	0.817	0.183	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.816	0.184	0.000
I15 Secondary hypertension	0.816	0.184	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.814	0.186	0.000
E11.7 With multiple complications	0.813	0.187	0.000
N19 Unspecified renal failure	0.807	0.193	0.000
E14.2 Withrenal complications	0.806	0.194	0.000
M05.8 Other seropositive rheumatoid arthritis	0.000	0.195	0.805
I12.9 Hypertensive renal disease without renal failure	0.800	0.200	0.000
I74 Arterial embolism and thrombosis	0.799	0.201	0.000
E11.1 With ketoacidosis	0.798	0.202	0.000
H34.9 Retinal vascular occlusion, unspecified	0.798	0.202	0.000
H35.4 Peripheral retinal degeneration	0.798	0.202	0.000
K74.6 Other and unspecified cirrhosis of liver	0.796	0.204	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.204	0.796
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.795	0.205	0.000
N05.2 Diffuse membranous glomerulonephritis	0.794	0.206	0.000
E10.7 With multiple complications	0.793	0.207	0.000
H49 Paralytic strabismus	0.792	0.208	0.000
E14.1 With ketoacidosis	0.789	0.211	0.000
D64.3 Other sideroblastic anaemias	0.788	0.211	0.000
H02 Other disorders of eyelid	0.787	0.213	0.000
H02.3 Blepharochalasis	0.787	0.213	0.000
H34.2 Other retinal artery occlusions	0.783	0.217	0.000
K73 Chronic hepatitis, not elsewhere classified	0.781	0.219	0.000
I15.1 Hypertension secondary to other renal disorders	0.781	0.219	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.779	0.221	0.000
D55-D59 Haemolytic anaemias	0.777	0.223	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.777	0.223	0.000
E14.4 With neurological complications	0.776	0.224	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.775	0.225	0.000
H50.6 Mechanical strabismus	0.772	0.228	0.000
H02.4 Ptosis of eyelid	0.768	0.232	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.232	0.768
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.766	0.234	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.765	0.235	0.000
I12.0 Hypertensive renal disease with renal failure	0.764	0.236	0.000
H05.2 Exophthalmic conditions	0.764	0.236	0.000
E13 Other specified diabetes mellitus	0.763	0.237	0.000
E16.1 Other hypoglycaemia	0.763	0.237	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.237	0.763
H35.5 Hereditary retinal dystrophy	0.761	0.239	0.000
N00 Acute nephritic syndrome	0.759	0.241	0.000
I74.5 Embolism and thrombosis of iliac artery	0.759	0.241	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.246	0.754
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.753	0.247	0.000
E03 Other hypothyroidism	0.753	0.247	0.000
K90.8 Other intestinal malabsorption	0.747	0.253	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.747	0.253	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.746	0.254	0.000
N04.2 Diffuse membranous glomerulonephritis	0.745	0.255	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.255	0.745
M05.2 Rheumatoid vasculitis	0.000	0.259	0.741
H05.8 Other disorders of orbit	0.741	0.259	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.740	0.260	0.000
N18.2 Chronic kidney disease, stage 2	0.740	0.260	0.000
K72.0 Acute and subacute hepatic failure	0.739	0.261	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.262	0.738
H54.4 Blindness, one eye	0.738	0.262	0.000
N04.0 Minor glomerular abnormality	0.737	0.263	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.265	0.735
E10.6 With other specified complications	0.734	0.266	0.000
E14.6 With other specified complications	0.731	0.269	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.270	0.730
D63 Anaemia in chronic diseases classified elsewhere	0.730	0.270	0.000
K77 Liver disorders in diseases classified elsewhere	0.730	0.270	0.000
N18.4 Chronic kidney disease, stage 4	0.728	0.272	0.000
N05.8 Other	0.727	0.272	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.727	0.273	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.726	0.274	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.725	0.275	0.000
H54.0 Blindness, both eyes	0.724	0.276	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.279	0.721
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.720	0.280	0.000
M05.1 Rheumatoid lung disease	0.000	0.280	0.720
K72.1 Chronic hepatic failure	0.719	0.281	0.000
H54.5 Low vision, one eye	0.718	0.282	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.717	0.283	0.000
N06 Isolated proteinuria with specified morphological lesion	0.717	0.283	0.000
N01 Rapidly progressive nephritic syndrome	0.717	0.283	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.717	0.283	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.717	0.283	0.000
E14.7 With multiple complications	0.717	0.283	0.000
E14.0 With coma	0.717	0.283	0.000
N08.8 Glomerular disorders in other diseases classified elsewhere	0.717	0.283	0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.717	0.283	0.000
N08.1 Glomerular disorders in neoplastic diseases	0.717	0.283	0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.717	0.283	0.000
K90.3 Pancreatic steatorrhoea	0.717	0.283	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.717	0.283	0.000
K90.1 Tropical sprue	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.717	0.283	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.716	0.283	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.716	0.283	0.000
E16.4 Abnormal secretion of gastrin	0.716	0.283	0.000
E16.3 Increased secretion of glucagon	0.716	0.283	0.000
D64.4 Congenital dyserythropoietic anaemia	0.716	0.284	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.716	0.284	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.716	0.284	0.000
D64.0 Hereditary sideroblastic anaemia	0.716	0.284	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.716	0.284	0.000
E00 Congenital iodine-deficiency syndrome	0.716	0.284	0.000
M06.2 Rheumatoid bursitis	0.000	0.284	0.716
M06.1 Adult-onset Still's disease	0.000	0.284	0.716
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.286	0.714
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.286	0.714
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.286	0.714
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.286	0.714
K74.0 Hepatic fibrosis	0.713	0.287	0.000
H06.2 Dysthyroid exophthalmos	0.713	0.287	0.000
N04.8 Other	0.711	0.289	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.711	0.289	0.000
N04.6 Dense deposit disease	0.711	0.289	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.711	0.289	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.711	0.289	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.711	0.289	0.000
D75.1 Secondary polycythaemia	0.710	0.290	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.291	0.709
N05.6 Dense deposit disease	0.709	0.291	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.709	0.291	0.000
N05.0 Minor glomerular abnormality	0.709	0.291	0.000
M08 Juvenile arthritis	0.000	0.292	0.708
H43.2 Crystalline deposits in vitreous body	0.708	0.292	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.293	0.707
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.293	0.707
D80.1 Nonfamilial hypogammaglobulinaemia	0.706	0.294	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.294	0.705
D89.9 Disorder involving the immune mechanism, unspecified	0.705	0.295	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.704	0.296	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.297	0.703
N17.2 Acute renal failure with medullary necrosis	0.702	0.298	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.298	0.702
K93 Disorders of other digestive organs in diseases classified elsewhere	0.700	0.300	0.000
G36 Other acute disseminated demyelination	0.005	0.303	0.692
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.697	0.303	0.000
H43.9 Disorder of vitreous body, unspecified	0.697	0.303	0.000
K70.0 Alcoholic fatty liver	0.696	0.304	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.694	0.306	0.000
E45 Retarded development following protein-energy malnutrition	0.694	0.306	0.000
E43 Unspecified severe protein-energy malnutrition	0.694	0.306	0.000
E42 Marasmic kwashiorkor	0.694	0.306	0.000
E41 Nutritional marasmus	0.694	0.306	0.000
E40 Kwashiorkor	0.694	0.306	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.693	0.307	0.000
N17.8 Other acute renal failure	0.692	0.308	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.310	0.690
M05.0 Felty's syndrome	0.000	0.312	0.688
K70.2 Alcoholic fibrosis and sclerosis of liver	0.688	0.312	0.000
M06.4 Inflammatory polyarthropathy	0.000	0.312	0.688
D74 Methaemoglobinaemia	0.687	0.313	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.687	0.313	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.687	0.313	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.314	0.686
I98 Other disorders of circulatory system in diseases classified elsewhere	0.683	0.317	0.000
H50.2 Vertical strabismus	0.682	0.318	0.000
H34.0 Transient retinal artery occlusion	0.682	0.318	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.681	0.319	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.680	0.320	0.000
H43.8 Other disorders of vitreous body	0.679	0.321	0.000
N18.1 Chronic kidney disease, stage 1	0.679	0.321	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.678	0.322	0.000
H52.6 Other disorders of refraction	0.677	0.323	0.000
H52.5 Disorders of accommodation	0.677	0.323	0.000
H35.1 Retinopathy of prematurity	0.675	0.324	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.325	0.675
D84 Other immunodeficiencies	0.674	0.326	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.673	0.327	0.000
E06 Thyroiditis	0.670	0.330	0.000
G37.5 Concentric sclerosis [Balo]	0.001	0.331	0.668
G37.4 Subacute necrotising myelitis	0.001	0.331	0.668
G37.2 Central pontine myelinolysis	0.001	0.331	0.668
G37.1 Central demyelination of corpus callosum	0.001	0.331	0.668
G37.0 Diffuse sclerosis	0.001	0.331	0.668
H50.5 Heterophoria	0.667	0.333	0.000
D81 Combined immunodeficiencies	0.666	0.334	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.335	0.665
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.335	0.665
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.335	0.665
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.335	0.665
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.335	0.665
H49.4 Progressive external ophthalmoplegia	0.665	0.335	0.000
D50-D53 Nutritional anaemias	0.665	0.335	0.000
K71 Toxic liver disease	0.664	0.335	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.663	0.337	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.662	0.338	0.000
D72 Other disorders of white blood cells	0.660	0.340	0.000
I13 Hypertensive heart and renal disease	0.660	0.340	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.342	0.657
M06.38 Rheumatoid nodule (Other)	0.000	0.342	0.657
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.342	0.657
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.342	0.657
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.342	0.657
H34.1 Central retinal artery occlusion	0.656	0.344	0.000
H10-H13 Disorders of conjunctiva	0.655	0.345	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.654	0.346	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.654	0.346	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.349	0.650
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.650	0.350	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.649	0.350	0.000
M12 Other specific arthropathies	0.000	0.352	0.648
H52.4 Presbyopia	0.647	0.353	0.000
I73 Other peripheral vascular diseases	0.646	0.354	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.645	0.355	0.000
H54.6 Unqualified visual loss, one eye	0.644	0.355	0.000
I00-I02 Acute rheumatic fever	0.644	0.356	0.000
H50.3 Intermittent heterotropia	0.643	0.357	0.000
E11.8 With unspecified complications	0.643	0.357	0.000
H54.2 Low vision, both eyes	0.639	0.361	0.000
E05.8 Other thyrotoxicosis	0.638	0.361	0.000
I15.9 Seconday hypertension, unspecified	0.638	0.361	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.363	0.637
H30 Chorioretinal inflammation	0.636	0.363	0.000
H51 Other disorders of binocular movement	0.635	0.365	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.634	0.366	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.634	0.366	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.634	0.366	0.000
D75.2 Essential thrombocytosis	0.633	0.367	0.000
H35.6 Retinal haemorrhage	0.633	0.367	0.000
D82 Immunodeficiency associated with other major defects	0.632	0.368	0.000
H43.0 Vitreous prolapse	0.631	0.369	0.000
M11 Other crystal arthropathies	0.000	0.372	0.628
M06.33 Rheumatoid nodule (Forearm)	0.000	0.372	0.627
D61 Other aplastic anaemias	0.626	0.374	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.625	0.375	0.000
H35.7 Separation of retinal layers	0.624	0.376	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.621	0.379	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.379	0.620
H52.1 Myopia	0.618	0.382	0.000
I06 Rheumatic aortic valve diseases	0.616	0.384	0.000
D59 Acquired haemolytic anaemia	0.615	0.385	0.000
N17.1 Acute renal failure with acute cortical necrosis	0.614	0.386	0.000
H49.9 Paralytic strabismus, unspecified	0.614	0.386	0.000
K74.4 Secondary biliary cirrhosis	0.613	0.387	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.613	0.387	0.000
K74.1 Hepatic sclerosis	0.613	0.387	0.000
H49.0 Third [oculomotor] nerve palsy	0.612	0.388	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.609	0.391	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.609	0.391	0.000
I27 Other pulmonary heart diseases	0.608	0.392	0.000
H05.1 Chronic inflammatory disorders of orbit	0.607	0.393	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.605	0.395	0.000
H52.7 Disorder of refraction, unspecified	0.604	0.396	0.000
K70.4 Alcoholic hepatic failure	0.603	0.397	0.000
M07 Psoriatic and enteropathic arthropathies	0.000	0.398	0.602
D56 Thalassaemia	0.601	0.399	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.598	0.402	0.000
I07.9 Tricuspid valve disease, unspecified	0.598	0.402	0.000
I07.8 Other tricuspid valve diseases	0.598	0.402	0.000
I07.2 Tricuspid stenosis with insufficiency	0.598	0.402	0.000
I07.0 Tricuspid stenosis	0.598	0.402	0.000
I73.9 Peripheral vascular disease, unspecified	0.595	0.405	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.591	0.409	0.000
E13.3 With ophthalmic complications	0.591	0.409	0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.587	0.413	0.000
H05.3 Deformity of orbit	0.587	0.413	0.000
D57 Sickle-cell disorders	0.587	0.413	0.000
N00.9 Unspecified	0.586	0.414	0.000
D89.3 Immune reconstitution syndrome	0.586	0.414	0.000
H54.3 Unqualified visual loss, both eyes	0.586	0.414	0.000
I15.8 Other secondary hypertension	0.585	0.415	0.000
I15.2 Hypertension secondary to endocrine disorders	0.585	0.415	0.000
H50.8 Other specified strabismus	0.582	0.418	0.000
I27.2 Other secondary pulmonary hypertension	0.579	0.421	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.578	0.422	0.000
I70 Atherosclerosis	0.578	0.422	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.000	0.423	0.577
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.000	0.423	0.577
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.000	0.423	0.577
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.000	0.423	0.577
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.000	0.423	0.577
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.000	0.423	0.577
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.000	0.423	0.577
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.000	0.423	0.577
D75.0 Familial erythrocytosis	0.576	0.424	0.000
N03 Chronic nephritic syndrome	0.575	0.425	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.574	0.425	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.000	0.427	0.573
D89.1 Cryoglobulinaemia	0.572	0.428	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.572	0.428	0.000
H31 Other disorders of choroid	0.571	0.428	0.000
D60.8 Other acquired pure red cell aplasias	0.570	0.430	0.000
D60.1 Transient acquired pure red cell aplasia	0.570	0.430	0.000
D60.0 Chronic acquired pure red cell aplasia	0.570	0.430	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.569	0.430	0.000
H49.3 Total (external) ophthalmoplegia	0.568	0.432	0.000
E50-E64 Other nutritional deficiencies	0.566	0.434	0.000
H02.7 Other degenerative disorders of eyelid and periocular area	0.564	0.436	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.000	0.437	0.563
D53 Other nutritional anaemias	0.562	0.438	0.000
D72.8 Other specified disorders of white blood cells	0.562	0.438	0.000
D83 Common variable immunodeficiency	0.561	0.438	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.560	0.440	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.560	0.440	0.000
K74.5 Biliary cirrhosis, unspecified	0.559	0.441	0.000
E03.8 Other specified hypothyroidism	0.558	0.442	0.000
D55 Anaemia due to enzyme disorders	0.557	0.443	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.557	0.443	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.557	0.443	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.557	0.443	0.000
N17.0 Acute renal failure with tubular necrosis	0.557	0.443	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.555	0.445	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.448	0.552
E13.9 Without complications	0.551	0.449	0.000
I79.1 Aortitis in diseases classified elsewhere	0.549	0.451	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.549	0.451	0.000
D76.3 Other histiocytosis syndromes	0.549	0.451	0.000
H49.1 Fourth [trochlear] nerve palsy	0.549	0.451	0.000
E13.8 With unspecified complications	0.547	0.453	0.000
E13.7 With multiple complications	0.547	0.453	0.000
E13.6 With other specified complications	0.547	0.453	0.000
E13.5 With peripheral circulatory complications	0.547	0.453	0.000
E13.4 With neurological complications	0.547	0.453	0.000
E13.2 With renal complications	0.547	0.453	0.000
E13.1 With ketoacidosis	0.547	0.453	0.000
E13.0 With coma	0.547	0.453	0.000
H05.4 Enophthalmos	0.546	0.454	0.000
N00.8 Other	0.544	0.456	0.000
N00.7 Diffuse crescentic glomerulonephritis	0.544	0.456	0.000
N00.6 Dense deposit disease	0.544	0.456	0.000
N00.5 Diffuse mesangiocapillary glomerulonephritis	0.544	0.456	0.000
N00.4 Diffuse endocapillary proliferative glomerulonephritis	0.544	0.456	0.000
N00.3 Diffuse mesangial proliferative glomerulonephritis	0.544	0.456	0.000
N00.2 Diffuse membranous glomerulonephritis	0.544	0.456	0.000
N00.1 Focal and segmental glomerular lesions	0.544	0.456	0.000
N00.0 Minor glomerular abnormality	0.544	0.456	0.000
H50.0 Convergent concomitant strabismus	0.544	0.456	0.000
I95 Hypotension	0.543	0.457	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.541	0.459	0.000
H43.3 Other vitreous opacities	0.541	0.459	0.000
H49.8 Other paralytic strabismus	0.540	0.459	0.000
H50.4 Other and unspecified heterotropia	0.540	0.460	0.000
E03.5 Myxoedema coma	0.540	0.460	0.000
E03.4 Atrophy of thyroid (acquired)	0.540	0.460	0.000
E03.3 Postinfectious hypothyroidism	0.540	0.460	0.000
K65-K67 Diseases of peritoneum	0.539	0.461	0.000
H10 Conjunctivitis	0.538	0.462	0.000
H05.0 Acute inflammation of orbit	0.532	0.468	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.000	0.469	0.531
M05.28 Rheumatoid vasculitis (Other)	0.000	0.469	0.531
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.000	0.469	0.531
M05.26 Rheumatoid vasculitis (Lower leg)	0.000	0.469	0.531
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.000	0.469	0.531
M05.24 Rheumatoid vasculitis (Hand)	0.000	0.469	0.531
M05.23 Rheumatoid vasculitis (Forearm)	0.000	0.469	0.531
M05.22 Rheumatoid vasculitis (Upper arm)	0.000	0.469	0.531
M05.21 Rheumatoid vasculitis (Shoulder region)	0.000	0.469	0.531
H02.6 Xanthelasma of eyelid	0.531	0.469	0.000
I95.1 Orthostatic hypotension	0.528	0.472	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.000	0.473	0.526
M08.0 Juvenile rheumatoid arthritis	0.000	0.475	0.524
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.476	0.523
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.477	0.523
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.477	0.523
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.477	0.523
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.477	0.523
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.477	0.523
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.477	0.523
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.477	0.523
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.477	0.523
D63.1 Anaemia in other chronic diseases classified elsewhere	0.523	0.477	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.523	0.477	0.000
D84.1 Defects in the complement system	0.522	0.478	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.522	0.478	0.000
N18.8 Other chronic renal failure	0.522	0.478	0.000
E06.3 Autoimmune thyroiditis	0.520	0.480	0.000
I15.0 Renovascular hypertension	0.518	0.482	0.000
H45.0 Vitreous haemorrhage in diseases classified elsewhere	0.517	0.483	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.516	0.484	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.516	0.484	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.516	0.484	0.000
M05.18 Rheumatoid lung disease (Other)	0.000	0.484	0.516
M05.17 Rheumatoid lung disease (Ankle and foot)	0.000	0.484	0.516
M05.16 Rheumatoid lung disease (Lower leg)	0.000	0.484	0.516
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.000	0.484	0.516

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations