TreeWAS – Variant ID: rs9289146

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.848	0.152
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.850	0.150
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.853	0.147
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.855	0.145
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.861	0.139
T39.0 Salicylates	0.000	0.862	0.138
T43.2 Other and unspecified antidepressants	0.000	0.864	0.136
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.869	0.131
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.875	0.125
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.877	0.123
T36 Poisoning by systemic antibiotics	0.000	0.880	0.120
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.880	0.119
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.883	0.116
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.884	0.116
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.885	0.115
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.886	0.114
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.891	0.109
T39.4 Antirheumatics, not elsewhere classified	0.000	0.891	0.109
T39.2 Pyrazolone derivatives	0.000	0.891	0.109
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.891	0.109
T43.6 Psychostimulants with abuse potential	0.000	0.892	0.108
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.893	0.107
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.893	0.107
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.893	0.107
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.893	0.107
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.896	0.104
T43.9 Psychotropic drug, unspecified	0.000	0.896	0.104
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.896	0.104
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.896	0.104
T45.0 Antiallergic and antiemetic drugs	0.000	0.897	0.103
T42.1 Iminostilbenes	0.000	0.899	0.101
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.899	0.101
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.901	0.099
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.901	0.099
T36.0 Penicillins	0.000	0.902	0.098
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.902	0.098
T46.1 Calcium-channel blockers	0.000	0.902	0.098
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.905	0.095
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.906	0.094
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.906	0.094
T42.3 Barbiturates	0.000	0.906	0.094
T42.2 Succinimides and oxazolidinediones	0.000	0.906	0.094
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.908	0.092
T42.0 Hydantoin derivatives	0.000	0.908	0.092
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.909	0.091
T38.9 Other and unspecified hormone antagonists	0.000	0.911	0.088
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.911	0.088
T38.7 Androgens and anabolic congeners	0.000	0.911	0.088
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.911	0.088
T38.5 Other oestrogens and progestogens	0.000	0.911	0.088
T38.4 Oral contraceptives	0.000	0.911	0.088
T38.2 Antithyroid drugs	0.000	0.911	0.088
T38.1 Thyroid hormones and substitutes	0.000	0.911	0.088
T38.0 Glucocorticoids and synthetic analogues	0.000	0.911	0.088
T42.4 Benzodiazepines	0.000	0.913	0.087
T36.9 Systemic antibiotic, unspecified	0.000	0.914	0.086
T36.8 Other systemic antibiotics	0.000	0.914	0.086
T36.7 Antifungal antibiotics, systemically used	0.000	0.914	0.086
T36.6 Rifamycins	0.000	0.914	0.086
T36.5 Aminoglycosides	0.000	0.914	0.086
T36.4 Tetracyclines	0.000	0.914	0.086
T36.3 Macrolides	0.000	0.914	0.086
T36.2 Chloramphenicol group	0.000	0.914	0.086
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.914	0.086
T40.6 Other and unspecified narcotics	0.000	0.914	0.086
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.914	0.086
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.914	0.086
T46.7 Peripheral vasodilators	0.000	0.914	0.086
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.914	0.086
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.914	0.086
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.914	0.086
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.914	0.086
T40.4 Other synthetic narcotics	0.000	0.915	0.085
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.916	0.084
T45.8 Other primarily systemic and haematological agents	0.000	0.916	0.084
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.916	0.084
T45.6 Fibrinolysis-affecting drugs	0.000	0.916	0.084
T45.4 Iron and its compounds	0.000	0.916	0.084
T45.3 Enzymes, not elsewhere classified	0.000	0.916	0.084
T45.2 Vitamins, not elsewhere classified	0.000	0.916	0.084
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.917	0.083
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.917	0.083
T47.7 Emetics	0.000	0.917	0.083
T47.6 Antidiarrhoeal drugs	0.000	0.917	0.083
T47.5 Digestants	0.000	0.917	0.083
T47.4 Other laxatives	0.000	0.917	0.083
T47.3 Saline and osmotic laxatives	0.000	0.917	0.083
T47.2 Stimulant laxatives	0.000	0.917	0.083
T47.0 Histamine H(2)-receptor antagonists	0.000	0.917	0.083
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.922	0.078
T40.8 Lysergide [LSD]	0.000	0.922	0.078
T40.7 Cannabis (derivatives)	0.000	0.922	0.078
T40.5 Cocaine	0.000	0.922	0.078
T40.3 Methadone	0.000	0.922	0.078
T40.1 Heroin	0.000	0.922	0.078
T40.0 Opium	0.000	0.922	0.078
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.923	0.077
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.923	0.077
T37.5 Antiviral drugs	0.000	0.923	0.077
T37.4 Anthelminthics	0.000	0.923	0.077
T37.3 Other antiprotozoal drugs	0.000	0.923	0.077
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.923	0.077
T37.1 Antimycobacterial drugs	0.000	0.923	0.077
T37.0 Sulphonamides	0.000	0.923	0.077
T41.5 Therapeutic gases	0.000	0.923	0.077
T41.4 Anaesthetic, unspecified	0.000	0.923	0.077
T41.3 Local anaesthetics	0.000	0.923	0.077
T41.2 Other and unspecified general anaesthetics	0.000	0.923	0.077
T41.1 Intravenous anaesthetics	0.000	0.923	0.077
T41.0 Inhaled anaesthetics	0.000	0.923	0.077
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.923	0.077
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.923	0.077
T48.5 Anti-common-cold drugs	0.000	0.923	0.077
T48.4 Expectorants	0.000	0.923	0.077
T48.3 Antitussives	0.000	0.923	0.077
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.923	0.077
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.923	0.077
T48.0 Oxytocic drugs	0.000	0.923	0.077
T49.9 Topical agent, unspecified	0.000	0.923	0.077
T49.8 Other topical agents	0.000	0.923	0.077
T49.7 Dental drugs, topically applied	0.000	0.923	0.077
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.923	0.077
T49.5 Ophthalmological drugs and preparations	0.000	0.923	0.077
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.923	0.077
T49.3 Emollients, demulcents and protectants	0.000	0.923	0.077
T49.2 Local astringents and local detergents	0.000	0.923	0.077
T49.1 Antipruritics	0.000	0.923	0.077
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.923	0.077
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.924	0.076
T50.8 Diagnostic agents	0.000	0.929	0.071
T50.7 Analeptics and opioid receptor antagonists	0.000	0.929	0.071
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.929	0.071
T50.5 Appetite depressants	0.000	0.929	0.071
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.929	0.071
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.929	0.071
T50.1 Loop [high-ceiling] diuretics	0.000	0.929	0.071
T50.0 Mineralocorticoids and their antagonists	0.000	0.929	0.071
T45.5 Anticoagulants	0.000	0.929	0.070
T50.4 Drugs affecting uric acid metabolism	0.000	0.932	0.068
T39.1 4-Aminophenol derivatives	0.000	0.932	0.068
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.933	0.067
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.933	0.066
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.934	0.066
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.934	0.066
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.934	0.066
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.934	0.066
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.934	0.066
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.934	0.066
T44.0 Anticholinesterase agents	0.000	0.934	0.066
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.934	0.066
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.939	0.060
T40.2 Other opioids	0.000	0.942	0.058
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.943	0.057
N89.8 Other specified noninflammatory disorders of vagina	0.029	0.971	0.000
N89 Other noninflammatory disorders of vagina	0.025	0.975	0.000
N89.5 Stricture and atresia of vagina	0.025	0.975	0.000
N89.6 Tight hymenal ring	0.021	0.979	0.000
N89.7 Haematocolpos	0.018	0.982	0.000
N89.4 Leukoplakia of vagina	0.018	0.982	0.000
N89.3 Dysplasia of vagina, unspecified	0.018	0.982	0.000
N89.2 Severe vaginal dysplasia, not elsewhere classified	0.018	0.982	0.000
N89.1 Moderate vaginal dysplasia	0.018	0.982	0.000
N89.0 Mild vaginal dysplasia	0.018	0.982	0.000
N89.9 Noninflammatory disorder of vagina, unspecified	0.018	0.982	0.000
O63.1 Prolonged second stage (of labour)	0.010	0.990	0.000
O82.0 Delivery by elective Caesarean section	0.010	0.990	0.000
O63.0 Prolonged first stage (of labour)	0.009	0.991	0.000
C90.0 Multiple myeloma	0.008	0.992	0.000
O63 Long labour	0.008	0.992	0.000
G35 Multiple sclerosis	0.006	0.994	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.006	0.994	0.000
F40.2 Specific (isolated) phobias	0.006	0.994	0.000
C25.9 Pancreas, unspecified	0.000	0.994	0.006
O63.9 Long labour, unspecified	0.005	0.995	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.995	0.005
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.005	0.995	0.000
N88.8 Other specified noninflammatory disorders of cervix uteri	0.000	0.995	0.005
N36.2 Urethral caruncle	0.005	0.995	0.000
N36.3 Prolapsed urethral mucosa	0.005	0.995	0.000
Z29.0 Isolation	0.004	0.995	0.000
N36 Other disorders of urethra	0.004	0.996	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.996	0.004
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.996	0.004
O82 Single delivery by Caesarean section	0.004	0.996	0.000
I84.5 External haemorrhoids without complication	0.000	0.996	0.004
N36.8 Other specified disorders of urethra	0.004	0.996	0.000
C25 Malignant neoplasm of pancreas	0.000	0.996	0.004
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.004	0.996	0.000
M85.8 Other specified disorders of bone density and structure	0.000	0.996	0.004
C25.2 Tail of pancreas	0.000	0.996	0.003
N36.1 Urethral diverticulum	0.003	0.996	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.000	0.997	0.003
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.000	0.997	0.003
Z35.0 Supervision of pregnancy with history of infertility	0.000	0.997	0.003
M75.3 Calcific tendinitis of shoulder	0.003	0.997	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
C25.1 Body of pancreas	0.000	0.997	0.003
H43.3 Other vitreous opacities	0.000	0.997	0.003
N48.4 Impotence of organic origin	0.003	0.997	0.000
N36.0 Urethral fistula	0.003	0.997	0.000
C25.0 Head of pancreas	0.000	0.997	0.003
N36.9 Urethral disorder, unspecified	0.003	0.997	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.997	0.003
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.000	0.997	0.003
O82.8 Other single delivery by Caesarean section	0.003	0.997	0.000
O82.2 Delivery by Caesarean hysterectomy	0.003	0.997	0.000
Z29.2 Other prophylactic chemotherapy	0.003	0.997	0.000
C25.8 Overlapping lesion of pancreas	0.000	0.997	0.003
C25.7 Other parts of pancreas	0.000	0.997	0.003
C25.4 Endocrine pancreas	0.000	0.997	0.003
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.000	0.997	0.003
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.000	0.997	0.003
M85.84 Other specified disorders of bone density and structure (Hand)	0.000	0.997	0.003
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.000	0.997	0.003
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.000	0.997	0.003
S52.60 Fracture of lower end of both ulna and radius (closed)	0.003	0.997	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.000	0.997	0.003
H92.0 Otalgia	0.003	0.997	0.000
O82.9 Delivery by Caesarean section, unspecified	0.003	0.997	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.997	0.003
M85.88 Other specified disorders of bone density and structure (Other)	0.000	0.997	0.003
C25.3 Pancreatic duct	0.000	0.997	0.003
M85.83 Other specified disorders of bone density and structure (Forearm)	0.000	0.997	0.002
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.000	0.997	0.003
C90 Multiple myeloma and malignant plasma cell neoplasms	0.003	0.997	0.000
Z29 Need for other prophylactic measures	0.003	0.997	0.000
O03.4 Incomplete, without complication	0.000	0.997	0.003
O82.1 Delivery by emergency Caesarean section	0.002	0.997	0.000
F40 Phobic anxiety disorders	0.003	0.997	0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.003	0.997	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.000	0.997	0.002
M85.65 Other cyst of bone (Pelvic region and thigh)	0.000	0.998	0.002
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.000	0.998	0.002
G35-G37 Demyelinating diseases of the central nervous system	0.002	0.998	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.002	0.998	0.000
H57.1 Ocular pain	0.002	0.998	0.000
M85.6 Other cyst of bone	0.000	0.998	0.002
I89.0 Lymphoedema, not elsewhere classified	0.002	0.998	0.000
G36 Other acute disseminated demyelination	0.002	0.998	0.000
M85 Other disorders of bone density and structure	0.000	0.998	0.002
G36.0 Neuromyelitis optica [Devic]	0.002	0.998	0.000
O03.9 Complete or unspecified, without complication	0.000	0.998	0.002
N35.9 Urethral stricture, unspecified	0.002	0.998	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.000	0.998	0.002
I67.8 Other specified cerebrovascular diseases	0.002	0.998	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
F40.9 Phobic anxiety disorder, unspecified	0.002	0.998	0.000
O80.9 Single spontaneous delivery, unspecified	0.000	0.998	0.002
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.998	0.002
C90.1 Plasma cell leukaemia	0.002	0.998	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.998	0.002
N48.6 Balanitis xerotica obliterans	0.002	0.998	0.000
Z29.9 Prophylactic measure, unspecified	0.002	0.998	0.000
C90.3 Solitary plasmacytoma	0.002	0.998	0.000
F40.8 Other phobic anxiety disorders	0.002	0.998	0.000
F40.1 Social phobias	0.002	0.998	0.000
Z63.6 Dependent relative needing care at home	0.002	0.998	0.000
Q61.2 Polycystic kidney, adult type	0.002	0.998	0.000
J45.0 Predominantly allergic asthma	0.000	0.998	0.002
O03 Spontaneous abortion	0.000	0.998	0.002
M62.89 Other specified disorders of muscle (Site unspecified)	0.002	0.998	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.002	0.998	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.002	0.998	0.000
M48.09 Spinal stenosis (Site unspecified)	0.000	0.998	0.002
M85.69 Other cyst of bone (Site unspecified)	0.000	0.998	0.002
M85.68 Other cyst of bone (Other)	0.000	0.998	0.002
M85.63 Other cyst of bone (Forearm)	0.000	0.998	0.002
M85.62 Other cyst of bone (Upper arm)	0.000	0.998	0.002
M85.61 Other cyst of bone (Shoulder region)	0.000	0.998	0.002
M85.60 Other cyst of bone (Multiple sites)	0.000	0.998	0.002
N48.0 Leukoplakia of penis	0.002	0.998	0.000
G36.9 Acute disseminated demyelination, unspecified	0.002	0.998	0.000
G36.8 Other specified acute disseminated demyelination	0.002	0.998	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.002	0.998	0.000
M85.9 Disorder of bone density and structure, unspecified	0.000	0.998	0.002
M85.5 Aneurysmal bone cyst	0.000	0.998	0.002
M85.4 Solitary bone cyst	0.000	0.998	0.002
M85.3 Osteitis condensans	0.000	0.998	0.002
M85.1 Skeletal fluorosis	0.000	0.998	0.002
M85.0 Fibrous dysplasia (monostotic)	0.000	0.998	0.002
M62.86 Other specified disorders of muscle (Lower leg)	0.002	0.998	0.000
M62.88 Other specified disorders of muscle (Other)	0.002	0.998	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.000	0.998	0.002
N88 Other noninflammatory disorders of cervix uteri	0.000	0.998	0.002
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.002	0.998	0.000
M85.64 Other cyst of bone (Hand)	0.000	0.998	0.002
M85.66 Other cyst of bone (Lower leg)	0.000	0.998	0.002
S02.50 Fracture of tooth (closed)	0.002	0.998	0.000
M62.8 Other specified disorders of muscle	0.002	0.998	0.000
O14.1 Severe preeclampsia	0.002	0.998	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.998	0.002
F40.0 Agoraphobia	0.002	0.998	0.000
L30.8 Other specified dermatitis	0.002	0.998	0.000
K14.8 Other diseases of tongue	0.002	0.998	0.000
M85.2 Hyperostosis of skull	0.000	0.998	0.002
N48 Other disorders of penis	0.002	0.998	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.000	0.998	0.002
O03.7 Complete or unspecified, complicated by embolism	0.000	0.998	0.002
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.998	0.002
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.998	0.002
O03.3 Incomplete, with other and unspecified complications	0.000	0.998	0.002
O03.2 Incomplete, complicated by embolism	0.000	0.998	0.002
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.998	0.002
Q61.9 Cystic kidney disease, unspecified	0.002	0.998	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.000	0.998	0.002
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.998	0.002
H06.2 Dysthyroid exophthalmos	0.000	0.998	0.002
I27.0 Primary pulmonary hypertension	0.002	0.998	0.000
N48.5 Ulcer of penis	0.002	0.998	0.000
Q61 Cystic kidney disease	0.002	0.998	0.000
H57.0 Anomalies of pupillary function	0.002	0.998	0.000
Q61.5 Medullary cystic kidney	0.002	0.998	0.000
Z63.5 Disruption of family by separation and divorce	0.002	0.998	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.002	0.998	0.000
N88.1 Old laceration of cervix uteri	0.000	0.998	0.002
H52.3 Anisometropia and aniseikonia	0.000	0.998	0.002
H52.1 Myopia	0.000	0.998	0.002
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.000	0.998	0.001
M85.08 Fibrous dysplasia (monostotic) (Other)	0.000	0.998	0.001
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.000	0.998	0.001
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.000	0.998	0.001
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.000	0.998	0.001
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.000	0.998	0.001
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.000	0.998	0.001
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.000	0.998	0.001
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.000	0.998	0.001
M85.19 Skeletal fluorosis (Site unspecified)	0.000	0.998	0.001
M85.18 Skeletal fluorosis (Other)	0.000	0.998	0.001
M85.17 Skeletal fluorosis (Ankle and foot)	0.000	0.998	0.001
M85.16 Skeletal fluorosis (Lower leg)	0.000	0.998	0.001
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.000	0.998	0.001
M85.14 Skeletal fluorosis (Hand)	0.000	0.998	0.001
M85.13 Skeletal fluorosis (Forearm)	0.000	0.998	0.001
M85.12 Skeletal fluorosis (Upper arm)	0.000	0.998	0.001
M85.11 Skeletal fluorosis (Shoulder region)	0.000	0.998	0.001
M85.10 Skeletal fluorosis (Multiple sites)	0.000	0.998	0.001
M85.39 Osteitis condensans (Site unspecified)	0.000	0.998	0.001
M85.38 Osteitis condensans (Other)	0.000	0.998	0.001
M85.37 Osteitis condensans (Ankle and foot)	0.000	0.998	0.001
M85.36 Osteitis condensans (Lower leg)	0.000	0.998	0.001
M85.35 Osteitis condensans (Pelvic region and thigh)	0.000	0.998	0.001
M85.34 Osteitis condensans (Hand)	0.000	0.998	0.001
M85.33 Osteitis condensans (Forearm)	0.000	0.998	0.001
M85.32 Osteitis condensans (Upper arm)	0.000	0.998	0.001
M85.31 Osteitis condensans (Shoulder region)	0.000	0.998	0.001
M85.30 Osteitis condensans (Multiple sites)	0.000	0.998	0.001
M85.49 Solitary bone cyst (Site unspecified)	0.000	0.998	0.001
M85.48 Solitary bone cyst (Other)	0.000	0.998	0.001
M85.47 Solitary bone cyst (Ankle and foot)	0.000	0.998	0.001
M85.46 Solitary bone cyst (Lower leg)	0.000	0.998	0.001
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.000	0.998	0.001
M85.44 Solitary bone cyst (Hand)	0.000	0.998	0.001
M85.43 Solitary bone cyst (Forearm)	0.000	0.998	0.001
M85.42 Solitary bone cyst (Upper arm)	0.000	0.998	0.001
M85.41 Solitary bone cyst (Shoulder region)	0.000	0.998	0.001
M85.40 Solitary bone cyst (Multiple sites)	0.000	0.998	0.001
M85.59 Aneurysmal bone cyst (Site unspecified)	0.000	0.998	0.001
M85.58 Aneurysmal bone cyst (Other)	0.000	0.998	0.001
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.000	0.998	0.001
M85.56 Aneurysmal bone cyst (Lower leg)	0.000	0.998	0.001
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.000	0.998	0.001
M85.54 Aneurysmal bone cyst (Hand)	0.000	0.998	0.001
M85.53 Aneurysmal bone cyst (Forearm)	0.000	0.998	0.001
M85.52 Aneurysmal bone cyst (Upper arm)	0.000	0.998	0.001
M85.51 Aneurysmal bone cyst (Shoulder region)	0.000	0.998	0.001
M85.50 Aneurysmal bone cyst (Multiple sites)	0.000	0.998	0.001
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.000	0.998	0.001
M85.98 Disorder of bone density and structure, unspecified (Other)	0.000	0.998	0.001
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.000	0.998	0.001
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.000	0.998	0.001
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.000	0.998	0.001
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.000	0.998	0.001
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.000	0.998	0.001
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.000	0.998	0.001
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.000	0.998	0.001
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.000	0.998	0.001
C90.2 Plasmacytoma, extramedullary	0.001	0.998	0.000
Q87.4 Marfan's syndrome	0.002	0.998	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.002	0.998	0.000
N88.4 Hypertrophic elongation of cervix uteri	0.000	0.998	0.002
N88.3 Incompetence of cervix uteri	0.000	0.998	0.002
N88.2 Stricture and stenosis of cervix uteri	0.000	0.998	0.002
N88.0 Leukoplakia of cervix uteri	0.000	0.998	0.002
T51.9 Alcohol, unspecified	0.000	0.998	0.002
M62.84 Other specified disorders of muscle (Hand)	0.002	0.998	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.000	0.998	0.001
H57 Other disorders of eye and adnexa	0.002	0.998	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.001	0.998	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.001	0.998	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.002	0.998	0.000
Z57.2 Occupational exposure to dust	0.002	0.998	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.002	0.998	0.000
R45.8 Other symptoms and signs involving emotional state	0.002	0.998	0.000
I36 Nonrheumatic tricuspid valve disorders	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.002	0.998	0.000
R06.4 Hyperventilation	0.000	0.998	0.002
Z03.3 Observation for suspected nervous system disorder	0.002	0.998	0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses	0.002	0.998	0.000
Z63.8 Other specified problems related to primary support group	0.002	0.998	0.000
Z63 Other problems related to primary support group, including family circumstances	0.002	0.998	0.000
M85.29 Hyperostosis of skull-Site unspec	0.000	0.998	0.001
M85.28 Hyperostosis of skull-Other	0.000	0.998	0.001
M85.27 Hyperostosis of skull-Ankle/Foot	0.000	0.998	0.001
M85.26 Hyperostosis of skull-Lower Leg	0.000	0.998	0.001
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.000	0.998	0.001
M85.24 Hyperostosis of skull-Hand	0.000	0.998	0.001
M85.23 Hyperostosis of skull-Forearm	0.000	0.998	0.001
M85.22 Hyperostosis of skull-Upper arm	0.000	0.998	0.001
M85.21 Hyperostosis of skull-Shldr region	0.000	0.998	0.001
N30.3 Trigonitis	0.002	0.998	0.000
N48.3 Priapism	0.001	0.998	0.000
Q61.3 Polycystic kidney, unspecified	0.002	0.998	0.000
N35 Urethral stricture	0.002	0.998	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.002	0.998	0.000
L40.9 Psoriasis, unspecified	0.000	0.998	0.002
S81.8 Open wound of other parts of lower leg	0.002	0.998	0.000
Y40.9 Systemic antibiotic, unspecified	0.000	0.998	0.002
Z29.1 Prophylactic immunotherapy	0.001	0.998	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.000	0.998	0.002
N35.8 Other urethral stricture	0.001	0.998	0.000
Q61.8 Other cystic kidney diseases	0.001	0.998	0.000
Q61.4 Renal dysplasia	0.001	0.998	0.000
Q61.1 Polycystic kidney, infantile type	0.001	0.998	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.001	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.001	0.998	0.000
K81.9 Cholecystitis, unspecified	0.000	0.998	0.002
O14.0 Moderate preeclampsia	0.001	0.998	0.000
R09.1 Pleurisy	0.000	0.998	0.002
Z29.8 Other specified prophylactic measures	0.001	0.998	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.001	0.998	0.000
Z73.8 Other problems related to life-management difficulty	0.001	0.998	0.000
N30.9 Cystitis, unspecified	0.002	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.999	0.001
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.001	0.999	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.001	0.999	0.000
M85.20 Hyperostosis of skull-Mult sites	0.001	0.999	0.001
L73.9 Follicular disorder, unspecified	0.001	0.999	0.000
M82.1 Osteoporosis in endocrine disorders	0.000	0.999	0.001
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.001	0.999	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.001	0.999	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.001	0.999	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.001	0.999	0.000
Q61.0 Congenital single renal cyst	0.001	0.999	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.001	0.999	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.001	0.999	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.001	0.999	0.000
R45.6 Physical violence	0.001	0.999	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.001	0.999	0.000
F50.0 Anorexia nervosa	0.001	0.999	0.000
Z63.9 Problem related to primary support group, unspecified	0.001	0.999	0.000
Z63.3 Absence of family member	0.001	0.999	0.000
Z63.2 Inadequate family support	0.001	0.999	0.000
Z63.1 Problems in relationship with parents and in-laws	0.001	0.999	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.001	0.999	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.001	0.999	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.001	0.999	0.000
I89.1 Lymphangitis	0.001	0.999	0.000
N35.1 Postinfective urethral stricture, not elsewhere classified	0.001	0.999	0.000
N35.0 Posttraumatic urethral stricture	0.001	0.999	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.999	0.001
M20.0 Deformity of finger(s)	0.000	0.999	0.001
Z22.8 Carrier of other infectious diseases	0.001	0.999	0.000
Z57.8 Occupational exposure to other risk-factors	0.001	0.999	0.000
G37 Other demyelinating diseases of central nervous system	0.001	0.999	0.000
F80.1 Expressive language disorder	0.001	0.999	0.000
Z32.0 Pregnancy, not (yet) confirmed	0.001	0.999	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.001	0.999	0.000
S82.21 Fracture of shaft of tibia (open)	0.000	0.999	0.001
I51.8 Other ill-defined heart diseases	0.001	0.999	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.001	0.999	0.000
R45.1 Restlessness and agitation	0.001	0.999	0.000
Z32.1 Pregnancy confirmed	0.001	0.999	0.000
Z63.7 Other stressful life events affecting family and household	0.001	0.999	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.001	0.999	0.000
M70.22 Olecranon bursitis-Upper arm	0.001	0.999	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.001	0.999	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.001	0.999	0.000
Z63.0 Problems in relationship with spouse or partner	0.001	0.999	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.001	0.999	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.001	0.999	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.000	0.999	0.001
M82.18 Osteoporosis in endocrine disorders (Other)	0.000	0.999	0.001
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.000	0.999	0.001
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.000	0.999	0.001
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.000	0.999	0.001
M82.14 Osteoporosis in endocrine disorders (Hand)	0.000	0.999	0.001
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.000	0.999	0.001
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.000	0.999	0.001
K81.1 Chronic cholecystitis	0.000	0.999	0.001
N48.2 Other inflammatory disorders of penis	0.001	0.999	0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.000	0.999	0.001
H52.2 Astigmatism	0.000	0.999	0.001
H57.8 Other specified disorders of eye and adnexa	0.001	0.999	0.000
O14.2 HELLP syndrome	0.001	0.999	0.000
R16.1 Splenomegaly, not elsewhere classified	0.001	0.999	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.000	0.999	0.001
H52 Disorders of refraction and accommodation	0.000	0.999	0.001
M48.00 Spinal stenosis (Multiple sites in spine)	0.000	0.999	0.001
N48.9 Disorder of penis, unspecified	0.001	0.999	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations