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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9295804
log Bayes Factor = 48.281
Chromosome 6   position 29,336,147  (GRCh37) Explore rs9295804 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
E10 Insulin-dependent diabetes mellitus
0.000 0.001 0.999
E10.9 Without complications
0.000 0.002 0.998
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.003 0.997
E10-E14 Diabetes mellitus
0.000 0.007 0.993
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.010 0.990
E16 Other disorders of pancreatic internal secretion
0.000 0.010 0.990
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.010 0.990
E16.2 Hypoglycaemia, unspecified
0.000 0.011 0.989
E00-E07 Disorders of thyroid gland
0.000 0.011 0.989
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.029 0.971
E10.3 With ophthalmic complications
0.000 0.043 0.957
E10.2 With renal complications
0.000 0.044 0.956
E10.4 With neurological complications
0.000 0.069 0.931
E16.1 Other hypoglycaemia
0.000 0.174 0.826
E13 Other specified diabetes mellitus
0.000 0.198 0.802
E05.8 Other thyrotoxicosis
0.000 0.201 0.799
E10.1 With ketoacidosis
0.000 0.202 0.798
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.210 0.790
E14 Unspecified diabetes mellitus
0.000 0.224 0.776
E10.7 With multiple complications
0.000 0.256 0.744
E05.5 Thyroid crisis or storm
0.000 0.285 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.285 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.285 0.715
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.285 0.715
E12 Malnutrition-related diabetes mellitus
0.000 0.288 0.712
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.290 0.710
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.290 0.710
E16.4 Abnormal secretion of gastrin
0.000 0.290 0.710
E16.3 Increased secretion of glucagon
0.000 0.290 0.710
E15 Nondiabetic hypoglycaemic coma
0.000 0.290 0.710
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.291 0.709
E00 Congenital iodine-deficiency syndrome
0.000 0.291 0.709
E10.6 With other specified complications
0.000 0.295 0.705
E10.0 With coma
0.000 0.303 0.697
E14.3 With ophthalmic complications
0.000 0.320 0.680
E13.9 Without complications
0.000 0.321 0.679
E40-E46 Malnutrition
0.000 0.333 0.667
E07 Other disorders of thyroid
0.000 0.355 0.645
E14.6 With other specified complications
0.000 0.379 0.621
E10.5 With peripheral circulatory complications
0.000 0.381 0.619
E14.8 With unspecified complications
0.000 0.384 0.616
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.411 0.589
E14.4 With neurological complications
0.000 0.414 0.586
E14.1 With ketoacidosis
0.000 0.423 0.577
E13.8 With unspecified complications
0.000 0.425 0.575
E13.7 With multiple complications
0.000 0.425 0.575
E13.6 With other specified complications
0.000 0.425 0.575
E13.5 With peripheral circulatory complications
0.000 0.425 0.575
E13.4 With neurological complications
0.000 0.425 0.575
E13.2 With renal complications
0.000 0.425 0.575
E13.1 With ketoacidosis
0.000 0.425 0.575
E13.0 With coma
0.000 0.425 0.575
E14.7 With multiple complications
0.000 0.444 0.556
E14.0 With coma
0.000 0.444 0.556
E06 Thyroiditis
0.000 0.449 0.551
E13.3 With ophthalmic complications
0.000 0.450 0.549
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.534 0.466 0.000
E07.8 Other specified disorders of thyroid
0.000 0.476 0.524
E14.2 Withrenal complications
0.000 0.478 0.522
E14.5 With peripheral circulatory complications
0.000 0.481 0.519
K90 Intestinal malabsorption
0.000 0.485 0.515
E12.9 Without complications
0.000 0.489 0.510
E12.8 With unspecified complications
0.000 0.489 0.510
E12.7 With multiple complications
0.000 0.489 0.510
E12.6 With other specified complications
0.000 0.489 0.510
E12.5 With peripheral circulatory complications
0.000 0.489 0.510
E12.4 With neurological complications
0.000 0.489 0.510
E12.3 With ophthalmic complications
0.000 0.489 0.510
E12.2 With renal complications
0.000 0.489 0.510
E12.1 With ketoacidosis
0.000 0.489 0.510
E12.0 With coma
0.000 0.489 0.510
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.492 0.508
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.492 0.508
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.492 0.508
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.492 0.508
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.492 0.508
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.492 0.508
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.492 0.508
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.492 0.508
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.522 0.478
E45 Retarded development following protein-energy malnutrition
0.000 0.522 0.478
E43 Unspecified severe protein-energy malnutrition
0.000 0.522 0.478
E42 Marasmic kwashiorkor
0.000 0.522 0.478
E41 Nutritional marasmus
0.000 0.522 0.478
E40 Kwashiorkor
0.000 0.522 0.478
E07.1 Dyshormogenetic goitre
0.000 0.538 0.462
E07.0 Hypersecretion of calcitonin
0.000 0.538 0.462
E10.8 With unspecified complications
0.001 0.546 0.453
E03 Other hypothyroidism
0.000 0.556 0.444
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.558 0.442
E46 Unspecified protein-energy malnutrition
0.000 0.565 0.435
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.568 0.432
E06.9 Thyroiditis, unspecified
0.000 0.571 0.429
E06.1 Subacute thyroiditis
0.000 0.589 0.411
E06.4 Drug-induced thyroiditis
0.000 0.605 0.395
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.605 0.395
E06.0 Acute thyroiditis
0.000 0.605 0.395
E06.5 Other chronic thyroiditis
0.000 0.609 0.391
K90.9 Intestinal malabsorption, unspecified
0.000 0.629 0.370
K90.3 Pancreatic steatorrhoea
0.000 0.631 0.369
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.631 0.369
K90.1 Tropical sprue
0.000 0.631 0.369
E65-E68 Obesity and other hyperalimentation
0.000 0.652 0.348
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.656 0.344
E44.1 Mild protein-energy malnutrition
0.000 0.657 0.343
E44.0 Moderate protein-energy malnutrition
0.000 0.657 0.343
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.670 0.330
K90.8 Other intestinal malabsorption
0.000 0.671 0.329
E83 Disorders of mineral metabolism
0.328 0.671 0.000
E03.5 Myxoedema coma
0.000 0.682 0.318
E03.4 Atrophy of thyroid (acquired)
0.000 0.682 0.318
E03.3 Postinfectious hypothyroidism
0.000 0.682 0.318
E03.1 Congenital hypothyroidism without goitre
0.000 0.684 0.315
E50-E64 Other nutritional deficiencies
0.000 0.687 0.313
E83.3 Disorders of phosphorus metabolism
0.304 0.696 0.000
E03.8 Other specified hypothyroidism
0.000 0.721 0.279
E07.9 Disorder of thyroid, unspecified
0.000 0.728 0.272
E67 Other hyperalimentation
0.000 0.750 0.250
E68 Sequelae of hyperalimentation
0.000 0.750 0.250
E83.9 Disorder of mineral metabolism, unspecified
0.246 0.754 0.000
E83.8 Other disorders of mineral metabolism
0.236 0.764 0.000
E83.2 Disorders of zinc metabolism
0.236 0.764 0.000
E83.0 Disorders of copper metabolism
0.236 0.764 0.000
E51 Thiamine deficiency
0.000 0.766 0.234
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.775 0.225
E50 Vitamin A deficiency
0.000 0.775 0.225
E60 Dietary zinc deficiency
0.000 0.775 0.225
E59 Dietary selenium deficiency
0.000 0.775 0.225
E54 Ascorbic acid deficiency
0.000 0.775 0.225
E52 Niacin deficiency [pellagra]
0.000 0.775 0.225
E11 Non-insulin-dependent diabetes mellitus
0.000 0.784 0.216
E65 Localised adiposity
0.000 0.789 0.211
E56 Other vitamin deficiencies
0.000 0.789 0.210
E11.6 With other specified complications
0.000 0.797 0.203
E63 Other nutritional deficiencies
0.000 0.798 0.202
E58 Dietary calcium deficiency
0.000 0.798 0.202
E55 Vitamin D deficiency
0.000 0.814 0.186
E61 Deficiency of other nutrient elements
0.000 0.815 0.185
E67.8 Other specified hyperalimentation
0.000 0.821 0.179
E67.3 Hypervitaminosis D
0.000 0.821 0.179
E67.2 Megavitamin-B6 syndrome
0.000 0.821 0.179
E67.1 Hypercarotenaemia
0.000 0.821 0.179
E67.0 Hypervitaminosis A
0.000 0.821 0.179
E51.2 Wernicke's encephalopathy
0.000 0.823 0.177
E53 Deficiency of other B group vitamins
0.000 0.828 0.172
E51.9 Thiamine deficiency, unspecified
0.000 0.832 0.168
E51.8 Other manifestations of thiamine deficiency
0.000 0.832 0.168
E51.1 Beriberi
0.000 0.832 0.168
E11.1 With ketoacidosis
0.000 0.834 0.166
E50.9 Vitamin A deficiency, unspecified
0.000 0.839 0.161
E50.8 Other manifestations of vitamin A deficiency
0.000 0.839 0.161
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.839 0.161
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.839 0.161
E50.5 Vitamin A deficiency with night blindness
0.000 0.839 0.161
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.839 0.161
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.839 0.161
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.839 0.161
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.839 0.161
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.839 0.161
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.839 0.161
E64.8 Sequelae of other nutritional deficiencies
0.000 0.839 0.161
E64.3 Sequelae of rickets
0.000 0.839 0.161
E64.2 Sequelae of vitamin C deficiency
0.000 0.839 0.161
E64.1 Sequelae of vitamin A deficiency
0.000 0.839 0.161
E64.0 Sequelae of protein-energy malnutrition
0.000 0.839 0.161
E11.7 With multiple complications
0.000 0.845 0.155
E83.4 Disorders of magnesium metabolism
0.152 0.848 0.000
E56.9 Vitamin deficiency, unspecified
0.000 0.849 0.151
E56.8 Deficiency of other vitamins
0.000 0.849 0.151
E56.0 Deficiency of vitamin E
0.000 0.849 0.151
E63.8 Other specified nutritional deficiencies
0.000 0.855 0.145
E63.1 Imbalance of constituents of food intake
0.000 0.855 0.145
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.855 0.145
E11.8 With unspecified complications
0.000 0.860 0.140
E11.2 With renal complications
0.000 0.860 0.140
E56.1 Deficiency of vitamin K
0.000 0.863 0.137
E55.0 Rickets, active
0.000 0.866 0.133
E53.9 Vitamin B deficiency, unspecified
0.000 0.867 0.133
E61.9 Deficiency of nutrient element, unspecified
0.000 0.867 0.132
E61.8 Deficiency of other specified nutrient elements
0.000 0.867 0.132
E61.7 Deficiency of multiple nutrient elements
0.000 0.867 0.132
E61.6 Vanadium deficiency
0.000 0.867 0.132
E61.5 Molybdenum deficiency
0.000 0.867 0.132
E61.4 Chromium deficiency
0.000 0.867 0.132
E61.3 Manganese deficiency
0.000 0.867 0.132
E61.0 Copper deficiency
0.000 0.867 0.132
E11.0 With coma
0.000 0.869 0.131
E53.1 Pyridoxine deficiency
0.000 0.877 0.123
E53.0 Riboflavin deficiency
0.000 0.877 0.123
E63.9 Nutritional deficiency, unspecified
0.000 0.877 0.122
E61.1 Iron deficiency
0.000 0.878 0.121
E14.9 Without complications
0.000 0.884 0.116
E06.3 Autoimmune thyroiditis
0.001 0.884 0.115
E11.5 With peripheral circulatory complications
0.000 0.891 0.109
E61.2 Magnesium deficiency
0.000 0.891 0.108
E11.3 With ophthalmic complications
0.000 0.899 0.101
E55.9 Vitamin D deficiency, unspecified
0.000 0.906 0.094
I83 Varicose veins of lower extremities
0.082 0.918 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.936 0.064
E11.4 With neurological complications
0.000 0.937 0.063
E20-E35 Disorders of other endocrine glands
0.000 0.939 0.061
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.056 0.944 0.000
E04 Other non-toxic goitre
0.004 0.946 0.050
E11.9 Without complications
0.000 0.946 0.054
I83.0 Varicose veins of lower extremities with ulcer
0.053 0.947 0.000
C20 Malignant neoplasm of rectum
0.000 0.948 0.052
E24 Cushing's syndrome
0.000 0.951 0.049
C15-C26 Malignant neoplasms of digestive organs
0.000 0.953 0.047
E53.8 Deficiency of other specified B group vitamins
0.000 0.954 0.046
C15 Malignant neoplasm of oesophagus
0.000 0.954 0.046
E25 Adrenogenital disorders
0.000 0.955 0.045
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.956 0.044
E32 Diseases of thymus
0.000 0.956 0.044
E30 Disorders of puberty, not elsewhere classified
0.000 0.956 0.044
E20 Hypoparathyroidism
0.000 0.957 0.043
C15.4 Middle third of oesophagus
0.000 0.957 0.043
C15.5 Lower third of oesophagus
0.000 0.958 0.042
E31 Polyglandular dysfunction
0.000 0.958 0.041
C25 Malignant neoplasm of pancreas
0.000 0.960 0.040
E22 Hyperfunction of pituitary gland
0.000 0.960 0.040
E29 Testicular dysfunction
0.000 0.960 0.040
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.960 0.040
E24.2 Drug-induced Cushing's syndrome
0.000 0.961 0.039
E03.9 Hypothyroidism, unspecified
0.000 0.961 0.039
E04.8 Other specified non-toxic goitre
0.003 0.961 0.036
C17 Malignant neoplasm of small intestine
0.000 0.961 0.039
E24.0 Pituitary-dependent Cushing's disease
0.000 0.962 0.038
E34 Other endocrine disorders
0.000 0.962 0.038
C17.0 Duodenum
0.000 0.963 0.037
E24.8 Other Cushing's syndrome
0.000 0.963 0.037
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.964 0.035
E24.3 Ectopic ACTH syndrome
0.000 0.964 0.035
E24.1 Nelson's syndrome
0.000 0.964 0.035
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.964 0.035
E21.3 Hyperparathyroidism, unspecified
0.000 0.965 0.035
C25.3 Pancreatic duct
0.000 0.966 0.034
C15.0 Cervical part of oesophagus
0.000 0.966 0.034
E24.9 Cushing's syndrome, unspecified
0.000 0.967 0.033
C25.1 Body of pancreas
0.000 0.967 0.033
C15.8 Overlapping lesion of oesophagus
0.000 0.967 0.033
C15.2 Abdominal part of oesophagus
0.000 0.967 0.033
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.967 0.033
E22.1 Hyperprolactinaemia
0.000 0.967 0.033
E28 Ovarian dysfunction
0.000 0.968 0.032
C25.4 Endocrine pancreas
0.000 0.968 0.032
E25.9 Adrenogenital disorder, unspecified
0.000 0.968 0.032
E25.8 Other adrenogenital disorders
0.000 0.968 0.032
C24.0 Extrahepatic bile duct
0.000 0.968 0.032
E30.9 Disorder of puberty, unspecified
0.000 0.968 0.032
E30.8 Other disorders of puberty
0.000 0.968 0.032
E30.1 Precocious puberty
0.000 0.968 0.032
E30.0 Delayed puberty
0.000 0.968 0.032
E32.9 Disease of thymus, unspecified
0.000 0.968 0.032
E32.8 Other diseases of thymus
0.000 0.968 0.032
E32.1 Abscess of thymus
0.000 0.968 0.032
E32.0 Persistent hyperplasia of thymus
0.000 0.968 0.032
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.968 0.032
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.968 0.032
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.968 0.032
C15.1 Thoracic part of oesophagus
0.000 0.968 0.032
C25.8 Overlapping lesion of pancreas
0.000 0.969 0.031
E20.8 Other hypoparathyroidism
0.000 0.969 0.031
E20.1 Pseudohypoparathyroidism
0.000 0.969 0.031
E20.0 Idiopathic hypoparathyroidism
0.000 0.969 0.031
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.969 0.031
E04.0 Non-toxic diffuse goitre
0.003 0.969 0.028
K90-K93 Other diseases of the digestive system
0.000 0.969 0.031
E20.9 Hypoparathyroidism, unspecified
0.000 0.970 0.030
E31.9 Polyglandular dysfunction, unspecified
0.000 0.970 0.030
E31.8 Other polyglandular dysfunction
0.000 0.970 0.030
E31.1 Polyglandular hyperfunction
0.000 0.970 0.030
E26 Hyperaldosteronism
0.000 0.970 0.029
C15.3 Upper third of oesophagus
0.000 0.970 0.030
C15.9 Oesophagus, unspecified
0.000 0.970 0.030
C25.2 Tail of pancreas
0.000 0.971 0.029
C17.1 Jejunum
0.000 0.971 0.029
E22.8 Other hyperfunction of pituitary gland
0.000 0.971 0.029
E29.9 Testicular dysfunction, unspecified
0.000 0.971 0.029
E29.8 Other testicular dysfunction
0.000 0.971 0.029
E29.0 Testicular hyperfunction
0.000 0.971 0.029
E21.4 Other specified disorders of parathyroid gland
0.000 0.971 0.029
E34.9 Endocrine disorder, unspecified
0.000 0.971 0.028
E34.3 Short stature, not elsewhere classified
0.000 0.972 0.028
E21.2 Other hyperparathyroidism
0.000 0.972 0.028
C25.9 Pancreas, unspecified
0.000 0.972 0.028
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.972 0.028
C17.8 Overlapping lesion of small intestine
0.000 0.972 0.028
C17.3 Meckel's diverticulum
0.000 0.972 0.028
E31.0 Autoimmune polyglandular failure
0.000 0.972 0.027
K14.8 Other diseases of tongue
0.000 0.973 0.027
E34.5 Androgen resistance syndrome
0.000 0.973 0.027
E34.4 Constitutional tall stature
0.000 0.973 0.027
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.973 0.027
E34.1 Other hypersecretion of intestinal hormones
0.000 0.973 0.027
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.973 0.027
C25.7 Other parts of pancreas
0.000 0.974 0.026
C24.8 Overlapping lesion of biliary tract
0.000 0.974 0.026
C24.9 Biliary tract, unspecified
0.000 0.974 0.025
E29.1 Testicular hypofunction
0.000 0.976 0.024
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.976 0.024
E34.8 Other specified endocrine disorders
0.000 0.976 0.023
E28.9 Ovarian dysfunction, unspecified
0.000 0.976 0.023
E28.8 Other ovarian dysfunction
0.000 0.976 0.023
E28.1 Androgen excess
0.000 0.976 0.023
E28.0 Oestrogen excess
0.000 0.976 0.023
E83.5 Disorders of calcium metabolism
0.023 0.977 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.977 0.023
E22.0 Acromegaly and pituitary gigantism
0.000 0.977 0.023
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.977 0.023
C17.9 Small intestine, unspecified
0.000 0.977 0.023
C25.0 Head of pancreas
0.000 0.977 0.023
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.978 0.022
E23 Hypofunction and other disorders of pituitary gland
0.000 0.978 0.022
E26.8 Other hyperaldosteronism
0.000 0.978 0.021
E26.1 Secondary hyperaldosteronism
0.000 0.978 0.021
E34.0 Carcinoid syndrome
0.000 0.978 0.021
E26.9 Hyperaldosteronism, unspecified
0.000 0.980 0.019
C23 Malignant neoplasm of gallbladder
0.000 0.980 0.019
E28.3 Primary ovarian failure
0.000 0.981 0.019
C18.9 Colon, unspecified
0.000 0.981 0.019
E28.2 Polycystic ovarian syndrome
0.000 0.982 0.018
C22.9 Liver, unspecified
0.000 0.982 0.018
Z71.8 Other specified counselling
0.018 0.982 0.000
C22.7 Other specified carcinomas of liver
0.000 0.982 0.017
C22.4 Other sarcomas of liver
0.000 0.982 0.017
C22.3 Angiosarcoma of liver
0.000 0.982 0.017
C22.2 Hepatoblastoma
0.000 0.982 0.017
E66 Obesity
0.000 0.983 0.017
C22.1 Intrahepatic bile duct carcinoma
0.000 0.983 0.017
C26.8 Overlapping lesion of digestive system
0.000 0.983 0.017
C26.1 Spleen
0.000 0.983 0.017
I83.1 Varicose veins of lower extremities with inflammation
0.016 0.983 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.983 0.016
C18 Malignant neoplasm of colon
0.000 0.984 0.016
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.984 0.016
K93.1 Megacolon in Chagas' disease
0.000 0.984 0.016
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.984 0.016
C17.2 Ileum
0.000 0.984 0.016
C21 Malignant neoplasm of anus and anal canal
0.000 0.984 0.016
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.984 0.016
E23.1 Drug-induced hypopituitarism
0.000 0.984 0.016
H40.2 Primary angle-closure glaucoma
0.016 0.984 0.000
C18.1 Appendix
0.000 0.986 0.014
R31 Unspecified haematuria
0.014 0.986 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.014 0.986 0.000
E04.9 Non-toxic goitre, unspecified
0.002 0.986 0.012
C24.1 Ampulla of Vater
0.001 0.987 0.013
C26.0 Intestinal tract, part unspecified
0.000 0.987 0.013
E70-E90 Metabolic disorders
0.007 0.987 0.006
E23.2 Diabetes insipidus
0.000 0.987 0.013
E27 Other disorders of adrenal gland
0.000 0.987 0.013
E23.6 Other disorders of pituitary gland
0.000 0.987 0.013
E66.1 Drug-induced obesity
0.000 0.987 0.012
C18.8 Overlapping lesion of colon
0.000 0.987 0.012
C26.9 Ill-defined sites within the digestive system
0.000 0.987 0.012
C21.2 Cloacogenic zone
0.000 0.988 0.011
E26.0 Primary hyperaldosteronism
0.001 0.988 0.011
K14 Diseases of tongue
0.000 0.988 0.012
K14.6 Glossodynia
0.000 0.989 0.011
E21.0 Primary hyperparathyroidism
0.000 0.989 0.011
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.989 0.010
E77 Disorders of glycoprotein metabolism
0.005 0.990 0.005
E76 Disorders of glycosaminoglycan metabolism
0.005 0.990 0.005
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.005 0.990 0.005
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.005 0.990 0.005
E27.5 Adrenomedullary hyperfunction
0.000 0.990 0.009
E27.0 Other adrenocortical overactivity
0.000 0.990 0.009
E27.1 Primary adrenocortical insufficiency
0.000 0.990 0.009
E70 Disorders of aromatic amino-acid metabolism
0.005 0.990 0.004
E72 Other disorders of amino-acid metabolism
0.005 0.991 0.004
E79 Disorders of purine and pyrimidine metabolism
0.005 0.991 0.004
E84 Cystic fibrosis
0.005 0.991 0.004
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.991 0.009
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.005 0.991 0.005
C18.2 Ascending colon
0.000 0.991 0.009
K14.1 Geographic tongue
0.000 0.991 0.009
K14.3 Hypertrophy of tongue papillae
0.000 0.991 0.009
E74 Other disorders of carbohydrate metabolism
0.005 0.991 0.004
E73 Lactose intolerance
0.004 0.991 0.005
E27.9 Disorder of adrenal gland, unspecified
0.000 0.991 0.008
K14.5 Plicated tongue
0.000 0.991 0.008
K14.4 Atrophy of tongue papillae
0.000 0.991 0.008
E85 Amyloidosis
0.004 0.992 0.004
C18.6 Descending colon
0.000 0.992 0.008
C18.4 Transverse colon
0.000 0.992 0.008
E04.1 Non-toxic single thyroid nodule
0.004 0.992 0.004
E66.0 Obesity due to excess calories
0.001 0.992 0.007
C18.7 Sigmoid colon
0.000 0.992 0.008
H40.5 Glaucoma secondary to other eye disorders
0.008 0.992 0.000
K14.2 Median rhomboid glossitis
0.000 0.992 0.007
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.992 0.007
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.992 0.008
C16 Malignant neoplasm of stomach
0.000 0.992 0.007
E80 Disorders of porphyrin and bilirubin metabolism
0.005 0.993 0.002
C21.1 Anal canal
0.000 0.993 0.007
E27.2 Addisonian crisis
0.000 0.993 0.007
E66.2 Extreme obesity with alveolar hypoventilation
0.001 0.993 0.007
E23.0 Hypopituitarism
0.000 0.993 0.007
E71.3 Disorders of fatty-acid metabolism
0.004 0.993 0.004
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.004 0.993 0.004
E71.1 Other disorders of branched-chain amino-acid metabolism
0.004 0.993 0.004
E71.0 Maple-syrup-urine disease
0.004 0.993 0.004
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.004 0.993 0.004
E76.8 Other disorders of glucosaminoglycan metabolism
0.004 0.993 0.004
E76.3 Mucopolysaccharidosis, unspecified
0.004 0.993 0.004
E76.2 Other mucopolysaccharidoses
0.004 0.993 0.004
E76.1 Mucopolysaccharidosis, type II
0.004 0.993 0.004
E76.0 Mucopolysaccharidosis, type I
0.004 0.993 0.004
E77.9 Disorder of glycoprotein metabolism, unspecified
0.004 0.993 0.004
E77.8 Other disorders of glycoprotein metabolism
0.004 0.993 0.004
E77.1 Defects in glycoprotein degradation
0.004 0.993 0.004
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.004 0.993 0.004
E88 Other metabolic disorders
0.003 0.993 0.004
E04.2 Non-toxic multinodular goitre
0.006 0.993 0.002
C21.0 Anus, unspecified
0.000 0.993 0.007
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.004 0.993 0.003
E70.8 Other disorders of aromatic amino-acid metabolism
0.004 0.993 0.003
E70.2 Disorders of tyrosine metabolism
0.004 0.993 0.003
E70.1 Other hyperphenylalaninaemias
0.004 0.993 0.003
E70.0 Classical phenylketonuria
0.004 0.993 0.003
E72.9 Disorder of amino-acid metabolism, unspecified
0.004 0.993 0.003
E72.8 Other specified disorders of amino-acid metabolism
0.004 0.993 0.003
E72.5 Disorders of glycine metabolism
0.004 0.993 0.003
E72.4 Disorders of ornithine metabolism
0.004 0.993 0.003
E72.3 Disorders of lysine and hydroxylysine metabolism
0.004 0.993 0.003
E72.2 Disorders of urea cycle metabolism
0.004 0.993 0.003
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.993 0.007
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.004 0.993 0.003
E79.8 Other disorders of purine and pyrimidine metabolism
0.004 0.993 0.003
E79.1 Lesch-Nyhan syndrome
0.004 0.993 0.003
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.004 0.993 0.003
E84.8 Cystic fibrosis with other manifestations
0.004 0.993 0.003
E84.1 Cystic fibrosis with intestinal manifestations
0.004 0.993 0.003
E70.3 Albinism
0.004 0.993 0.003
E75.6 Lipid storage disorder, unspecified
0.003 0.993 0.003
E75.4 Neuronal ceroid lipofuscinosis
0.003 0.993 0.003
E75.3 Sphingolipidosis, unspecified
0.003 0.993 0.003
E75.1 Other gangliosidosis
0.003 0.993 0.003
E75.0 GM2 gangliosidosis
0.003 0.993 0.003
E72.0 Disorders of amino-acid transport
0.004 0.993 0.003
E84.0 Cystic fibrosis with pulmonary manifestations
0.004 0.993 0.003
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.993 0.007
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.004 0.993 0.003
E84.9 Cystic fibrosis, unspecified
0.004 0.993 0.003
K14.0 Glossitis
0.000 0.993 0.007
E75.2 Other sphingolipidosis
0.003 0.993 0.003
I97.1 Other functional disturbances following cardiac surgery
0.000 0.993 0.007
E75.5 Other lipid storage disorders
0.003 0.993 0.004
E74.9 Disorder of carbohydrate metabolism, unspecified
0.003 0.993 0.003
E74.8 Other specified disorders of carbohydrate metabolism
0.003 0.993 0.003
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.003 0.993 0.003
E74.2 Disorders of galactose metabolism
0.003 0.993 0.003
E74.1 Disorders of fructose metabolism
0.003 0.993 0.003
E74.0 Glycogen storage disease
0.003 0.993 0.003
W22 Striking against or struck by other objects
0.000 0.993 0.007
E73.8 Other lactose intolerance
0.003 0.993 0.004
E73.1 Secondary lactase deficiency
0.003 0.993 0.004
E73.0 Congenital lactase deficiency
0.003 0.993 0.004
H40 Glaucoma
0.007 0.993 0.000
C18.3 Hepatic flexure
0.000 0.993 0.007
C22.0 Liver cell carcinoma
0.001 0.993 0.006
W22.3 Sports and athletics area
0.000 0.994 0.006
E85.8 Other amyloidosis
0.003 0.994 0.003
E85.2 Heredofamilial amyloidosis, unspecified
0.003 0.994 0.003
E85.1 Neuropathic heredofamilial amyloidosis
0.003 0.994 0.003
E85.0 Nonneuropathic heredofamilial amyloidosis
0.003 0.994 0.003
W22.2 School, other institution and public administrative area
0.000 0.994 0.006
W22.5 Trade and service area
0.000 0.994 0.006
E74.3 Other disorders of intestinal carbohydrate absorption
0.003 0.994 0.003
W22.9 Unspecified place
0.000 0.994 0.006
E85.3 Secondary systemic amyloidosis
0.003 0.994 0.003
E27.8 Other specified disorders of adrenal gland
0.000 0.994 0.006
L40.0 Psoriasis vulgaris
0.000 0.994 0.006
S20.8 Superficial injuries of other and unspecified parts of thorax
0.000 0.994 0.006
E73.9 Lactose intolerance, unspecified
0.002 0.994 0.004
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.006 0.994 0.000
E80.1 Porphyria cutanea tarda
0.005 0.994 0.001
S30.1 Contusion of abdominal wall
0.006 0.994 0.000
E85.9 Amyloidosis, unspecified
0.004 0.994 0.002
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.994 0.006
I97.0 Postcardiotomy syndrome
0.000 0.994 0.006
C16.5 Lesser curvature of stomach, unspecified
0.000 0.994 0.006
E80.6 Other disorders of bilirubin metabolism
0.004 0.994 0.001
E85.4 Organ-limited amyloidosis
0.002 0.994 0.003
E80.7 Disorder of bilirubin metabolism, unspecified
0.004 0.994 0.002
E80.5 Crigler-Najjar syndrome
0.004 0.994 0.002
E80.3 Defects of catalase and peroxydase
0.004 0.994 0.002
E80.0 Hereditary erythropoietic porphyria
0.004 0.994 0.002
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)
0.000 0.994 0.006
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.004 0.994 0.001
E88.9 Metabolic disorder, unspecified
0.002 0.995 0.004
W29.9 Unspecified place
0.005 0.995 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.005 0.995 0.000
C16.8 Overlapping lesion of stomach
0.000 0.995 0.005
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.995 0.005
E88.1 Lipodystrophy, not elsewhere classified
0.002 0.995 0.003
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.000 0.995 0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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