TreeWAS – Variant ID: rs9295931

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.000	1.000
L40 Psoriasis	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	0.000	0.000	1.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.002	0.998
E10.9 Without complications	0.000	0.003	0.997
L40.0 Psoriasis vulgaris	0.997	0.003	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.004	0.996
E10-E14 Diabetes mellitus	0.000	0.018	0.982
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.018	0.982
E10.4 With neurological complications	0.000	0.040	0.960
M07.39 Other psoriatic arthropathies (Site unspecified)	0.939	0.061	0.000
M07.3 Other psoriatic arthropathies	0.939	0.061	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.063	0.937
M07.30 Other psoriatic arthropathies (Multiple sites)	0.934	0.066	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.094	0.906
E10.3 With ophthalmic complications	0.000	0.096	0.904
E10.5 With peripheral circulatory complications	0.000	0.104	0.896
L40.8 Other psoriasis	0.891	0.109	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.116	0.884
E07 Other disorders of thyroid	0.000	0.120	0.880
E10.1 With ketoacidosis	0.000	0.133	0.867
L40.1 Generalised pustular psoriasis	0.854	0.146	0.000
E10.6 With other specified complications	0.000	0.167	0.833
E07.9 Disorder of thyroid, unspecified	0.000	0.169	0.831
M07.34 Other psoriatic arthropathies (Hand)	0.825	0.175	0.000
E10.2 With renal complications	0.000	0.187	0.813
E10.0 With coma	0.000	0.197	0.803
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.199	0.801
M07.36 Other psoriatic arthropathies (Lower leg)	0.801	0.199	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.780	0.220	0.000
E06 Thyroiditis	0.000	0.230	0.770
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.246	0.754
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.267	0.733
E05.8 Other thyrotoxicosis	0.000	0.283	0.717
E05.5 Thyroid crisis or storm	0.000	0.283	0.717
E05.4 Thyrotoxicosis factitia	0.000	0.283	0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.283	0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.283	0.717
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.717
E03.5 Myxoedema coma	0.000	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.000	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.000	0.283	0.717
E03.1 Congenital hypothyroidism without goitre	0.000	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.283	0.717
E10.7 With multiple complications	0.000	0.284	0.716
E50-E64 Other nutritional deficiencies	0.000	0.284	0.716
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.291	0.709
E12 Malnutrition-related diabetes mellitus	0.000	0.296	0.704
M07.38 Other psoriatic arthropathies (Other)	0.673	0.327	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.673	0.327	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.673	0.327	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.673	0.327	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.673	0.327	0.000
E15 Nondiabetic hypoglycaemic coma	0.000	0.328	0.672
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.351	0.649
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.351	0.649
E16.4 Abnormal secretion of gastrin	0.000	0.351	0.649
E16.3 Increased secretion of glucagon	0.000	0.351	0.649
E07.1 Dyshormogenetic goitre	0.000	0.369	0.631
E07.0 Hypersecretion of calcitonin	0.000	0.369	0.631
E03.8 Other specified hypothyroidism	0.000	0.397	0.603
E06.3 Autoimmune thyroiditis	0.000	0.400	0.600
E55 Vitamin D deficiency	0.000	0.437	0.562
E13 Other specified diabetes mellitus	0.000	0.441	0.559
E06.9 Thyroiditis, unspecified	0.000	0.441	0.559
E16.1 Other hypoglycaemia	0.000	0.443	0.557
E06.5 Other chronic thyroiditis	0.000	0.448	0.552
E06.4 Drug-induced thyroiditis	0.000	0.448	0.552
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.448	0.552
E06.1 Subacute thyroiditis	0.000	0.448	0.552
E06.0 Acute thyroiditis	0.000	0.448	0.552
E10.8 With unspecified complications	0.000	0.448	0.552
E65-E68 Obesity and other hyperalimentation	0.000	0.471	0.529
K90 Intestinal malabsorption	0.000	0.474	0.526
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.486	0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.486	0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.486	0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.486	0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.486	0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.486	0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.486	0.514
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.487	0.513
E63 Other nutritional deficiencies	0.000	0.487	0.513
E56 Other vitamin deficiencies	0.000	0.487	0.513
E51 Thiamine deficiency	0.000	0.487	0.513
E50 Vitamin A deficiency	0.000	0.487	0.513
E60 Dietary zinc deficiency	0.000	0.487	0.513
E59 Dietary selenium deficiency	0.000	0.487	0.513
E58 Dietary calcium deficiency	0.000	0.487	0.513
E54 Ascorbic acid deficiency	0.000	0.487	0.513
E52 Niacin deficiency [pellagra]	0.000	0.487	0.513
E12.9 Without complications	0.000	0.495	0.505
E12.8 With unspecified complications	0.000	0.495	0.505
E12.7 With multiple complications	0.000	0.495	0.505
E12.6 With other specified complications	0.000	0.495	0.505
E12.5 With peripheral circulatory complications	0.000	0.495	0.505
E12.4 With neurological complications	0.000	0.495	0.505
E12.3 With ophthalmic complications	0.000	0.495	0.505
E12.2 With renal complications	0.000	0.495	0.505
E12.1 With ketoacidosis	0.000	0.495	0.505
E12.0 With coma	0.000	0.495	0.505
E61 Deficiency of other nutrient elements	0.000	0.501	0.499
E40-E46 Malnutrition	0.001	0.511	0.488
E53 Deficiency of other B group vitamins	0.000	0.520	0.480
E14 Unspecified diabetes mellitus	0.000	0.536	0.463
E55.9 Vitamin D deficiency, unspecified	0.000	0.547	0.453
E07.8 Other specified disorders of thyroid	0.000	0.554	0.445
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.558	0.442
E04 Other non-toxic goitre	0.000	0.561	0.439
K90.9 Intestinal malabsorption, unspecified	0.000	0.583	0.417
M07 Psoriatic and enteropathic arthropathies	0.411	0.589	0.000
E14.3 With ophthalmic complications	0.000	0.594	0.406
E55.0 Rickets, active	0.000	0.597	0.403
E13.8 With unspecified complications	0.000	0.599	0.401
E13.7 With multiple complications	0.000	0.599	0.401
E13.6 With other specified complications	0.000	0.599	0.401
E13.5 With peripheral circulatory complications	0.000	0.599	0.401
E13.4 With neurological complications	0.000	0.599	0.401
E13.3 With ophthalmic complications	0.000	0.599	0.401
E13.2 With renal complications	0.000	0.599	0.401
E13.1 With ketoacidosis	0.000	0.599	0.401
E13.0 With coma	0.000	0.599	0.401
E67 Other hyperalimentation	0.000	0.621	0.379
E68 Sequelae of hyperalimentation	0.000	0.621	0.379
K90.3 Pancreatic steatorrhoea	0.000	0.622	0.377
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.622	0.377
K90.1 Tropical sprue	0.000	0.622	0.377
E50.9 Vitamin A deficiency, unspecified	0.000	0.632	0.368
E50.8 Other manifestations of vitamin A deficiency	0.000	0.632	0.368
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.632	0.368
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.632	0.368
E50.5 Vitamin A deficiency with night blindness	0.000	0.632	0.368
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.632	0.368
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.632	0.368
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.632	0.368
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.632	0.368
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.632	0.368
E51.9 Thiamine deficiency, unspecified	0.000	0.632	0.368
E51.8 Other manifestations of thiamine deficiency	0.000	0.632	0.368
E51.2 Wernicke's encephalopathy	0.000	0.632	0.368
E51.1 Beriberi	0.000	0.632	0.368
E56.9 Vitamin deficiency, unspecified	0.000	0.632	0.368
E56.8 Deficiency of other vitamins	0.000	0.632	0.368
E56.1 Deficiency of vitamin K	0.000	0.632	0.368
E56.0 Deficiency of vitamin E	0.000	0.632	0.368
E63.9 Nutritional deficiency, unspecified	0.000	0.632	0.368
E63.8 Other specified nutritional deficiencies	0.000	0.632	0.368
E63.1 Imbalance of constituents of food intake	0.000	0.632	0.368
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.632	0.368
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.632	0.368
E64.8 Sequelae of other nutritional deficiencies	0.000	0.632	0.368
E64.3 Sequelae of rickets	0.000	0.632	0.368
E64.2 Sequelae of vitamin C deficiency	0.000	0.632	0.368
E64.1 Sequelae of vitamin A deficiency	0.000	0.632	0.368
E64.0 Sequelae of protein-energy malnutrition	0.000	0.632	0.368
E61.2 Magnesium deficiency	0.000	0.635	0.365
E53.9 Vitamin B deficiency, unspecified	0.000	0.638	0.362
E61.9 Deficiency of nutrient element, unspecified	0.000	0.642	0.358
E61.8 Deficiency of other specified nutrient elements	0.000	0.642	0.358
E61.7 Deficiency of multiple nutrient elements	0.000	0.642	0.358
E61.6 Vanadium deficiency	0.000	0.642	0.358
E61.5 Molybdenum deficiency	0.000	0.642	0.358
E61.4 Chromium deficiency	0.000	0.642	0.358
E61.3 Manganese deficiency	0.000	0.642	0.358
E61.0 Copper deficiency	0.000	0.642	0.358
E44 Protein-energy malnutrition of moderate and mild degree	0.001	0.650	0.350
E45 Retarded development following protein-energy malnutrition	0.001	0.650	0.350
E43 Unspecified severe protein-energy malnutrition	0.001	0.650	0.350
E42 Marasmic kwashiorkor	0.001	0.650	0.350
E41 Nutritional marasmus	0.001	0.650	0.350
E40 Kwashiorkor	0.001	0.650	0.350
E04.9 Non-toxic goitre, unspecified	0.000	0.652	0.348
E53.1 Pyridoxine deficiency	0.000	0.655	0.344
E53.0 Riboflavin deficiency	0.000	0.655	0.344
E61.1 Iron deficiency	0.000	0.664	0.336
E14.7 With multiple complications	0.000	0.667	0.332
E14.6 With other specified complications	0.000	0.667	0.332
E14.2 Withrenal complications	0.000	0.667	0.332
E14.0 With coma	0.000	0.667	0.332
E14.1 With ketoacidosis	0.000	0.674	0.326
E66 Obesity	0.000	0.681	0.319
E14.8 With unspecified complications	0.000	0.682	0.318
E04.8 Other specified non-toxic goitre	0.000	0.685	0.315
E14.5 With peripheral circulatory complications	0.000	0.701	0.299
E66.8 Other obesity	0.000	0.701	0.299
E65 Localised adiposity	0.000	0.703	0.297
M07.6 Other enteropathic arthropathies	0.294	0.705	0.000
M07.5 Arthropathy in ulcerative colitis	0.294	0.705	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.294	0.705	0.000
M07.2 Psoriatic spondylitis	0.294	0.705	0.000
M07.1 Arthritis mutilans	0.294	0.705	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.294	0.705	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.713	0.287
E67.8 Other specified hyperalimentation	0.000	0.728	0.272
E67.3 Hypervitaminosis D	0.000	0.728	0.272
E67.2 Megavitamin-B6 syndrome	0.000	0.728	0.272
E67.1 Hypercarotenaemia	0.000	0.728	0.272
E67.0 Hypervitaminosis A	0.000	0.728	0.272
E04.0 Non-toxic diffuse goitre	0.000	0.731	0.268
E14.4 With neurological complications	0.000	0.731	0.268
K90.8 Other intestinal malabsorption	0.001	0.743	0.256
E13.9 Without complications	0.001	0.744	0.255
E44.1 Mild protein-energy malnutrition	0.001	0.749	0.251
E44.0 Moderate protein-energy malnutrition	0.001	0.749	0.251
E04.2 Non-toxic multinodular goitre	0.000	0.762	0.238
E20-E35 Disorders of other endocrine glands	0.000	0.765	0.235
E66.1 Drug-induced obesity	0.000	0.771	0.229
L40-L45 Papulosquamous disorders	0.225	0.774	0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.211	0.788	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.211	0.788	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.211	0.788	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.211	0.788	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.211	0.788	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.211	0.788	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.211	0.788	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.211	0.788	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.211	0.788	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.211	0.788	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.211	0.788	0.000
M07.18 Arthritis mutilans (Other)	0.211	0.788	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.211	0.788	0.000
M07.16 Arthritis mutilans (Lower leg)	0.211	0.788	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.211	0.788	0.000
M07.14 Arthritis mutilans (Hand)	0.211	0.788	0.000
M07.13 Arthritis mutilans (Forearm)	0.211	0.788	0.000
M07.12 Arthritis mutilans (Upper arm)	0.211	0.788	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.211	0.788	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.211	0.788	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.211	0.788	0.000
M07.28 Psoriatic spondylitis (Other)	0.211	0.788	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.211	0.788	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.211	0.788	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.211	0.788	0.000
M07.24 Psoriatic spondylitis (Hand)	0.211	0.788	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.211	0.788	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.211	0.788	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.211	0.788	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.211	0.788	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.211	0.788	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.211	0.788	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.211	0.788	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.211	0.788	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.211	0.788	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.211	0.788	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.211	0.788	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.211	0.788	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.211	0.788	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.211	0.788	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.211	0.788	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.211	0.788	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.211	0.788	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.211	0.788	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.211	0.788	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.211	0.788	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.211	0.788	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.211	0.788	0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.211	0.788	0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.211	0.788	0.000
M07.69 Other enteropathic arthropathies (Site unspecified)	0.211	0.788	0.000
M07.68 Other enteropathic arthropathies (Other)	0.211	0.788	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.211	0.788	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.211	0.788	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.211	0.788	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.211	0.788	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.211	0.788	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.211	0.788	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.211	0.788	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.211	0.788	0.000
E27 Other disorders of adrenal gland	0.000	0.789	0.211
E27.1 Primary adrenocortical insufficiency	0.000	0.792	0.208
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.802	0.198
E04.1 Non-toxic single thyroid nodule	0.000	0.807	0.193
E66.0 Obesity due to excess calories	0.000	0.830	0.169
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.831	0.169
E32 Diseases of thymus	0.000	0.831	0.169
E31 Polyglandular dysfunction	0.000	0.831	0.169
E30 Disorders of puberty, not elsewhere classified	0.000	0.831	0.169
E25 Adrenogenital disorders	0.000	0.831	0.169
E34 Other endocrine disorders	0.000	0.834	0.166
L44 Other papulosquamous disorders	0.162	0.838	0.000
L41 Parapsoriasis	0.162	0.838	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.162	0.838	0.000
E29 Testicular dysfunction	0.000	0.840	0.160
E20 Hypoparathyroidism	0.000	0.841	0.159
E27.8 Other specified disorders of adrenal gland	0.000	0.842	0.158
L42 Pityriasis rosea	0.156	0.843	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.848	0.152
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.848	0.152
E27.0 Other adrenocortical overactivity	0.000	0.848	0.152
E26 Hyperaldosteronism	0.000	0.854	0.146
E22 Hyperfunction of pituitary gland	0.000	0.855	0.145
E24 Cushing's syndrome	0.000	0.855	0.144
E27.2 Addisonian crisis	0.000	0.858	0.142
E28 Ovarian dysfunction	0.000	0.860	0.139
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.139	0.861	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.136	0.864	0.000
E46 Unspecified protein-energy malnutrition	0.002	0.865	0.133
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.135	0.865	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.135	0.865	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.869	0.131
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.128	0.872	0.000
T43.2 Other and unspecified antidepressants	0.125	0.875	0.000
E34.0 Carcinoid syndrome	0.000	0.875	0.124
E25.9 Adrenogenital disorder, unspecified	0.000	0.879	0.121
E25.8 Other adrenogenital disorders	0.000	0.879	0.121
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.879	0.121
E30.9 Disorder of puberty, unspecified	0.000	0.879	0.121
E30.8 Other disorders of puberty	0.000	0.879	0.121
E30.1 Precocious puberty	0.000	0.879	0.121
E30.0 Delayed puberty	0.000	0.879	0.121
E31.9 Polyglandular dysfunction, unspecified	0.000	0.879	0.121
E31.8 Other polyglandular dysfunction	0.000	0.879	0.121
E31.1 Polyglandular hyperfunction	0.000	0.879	0.121
E31.0 Autoimmune polyglandular failure	0.000	0.879	0.121
E32.9 Disease of thymus, unspecified	0.000	0.879	0.121
E32.8 Other diseases of thymus	0.000	0.879	0.121
E32.1 Abscess of thymus	0.000	0.879	0.121
E32.0 Persistent hyperplasia of thymus	0.000	0.879	0.121
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.879	0.121
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.879	0.121
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.879	0.121
E34.5 Androgen resistance syndrome	0.000	0.881	0.119
E34.4 Constitutional tall stature	0.000	0.881	0.119
E34.3 Short stature, not elsewhere classified	0.000	0.881	0.119
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.881	0.119
E34.1 Other hypersecretion of intestinal hormones	0.000	0.881	0.119
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.119	0.881	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.119	0.881	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.117	0.883	0.000
L41.9 Parapsoriasis, unspecified	0.116	0.884	0.000
L41.8 Other parapsoriasis	0.116	0.884	0.000
L41.5 Retiform parapsoriasis	0.116	0.884	0.000
L41.4 Large plaque parapsoriasis	0.116	0.884	0.000
L41.3 Small plaque parapsoriasis	0.116	0.884	0.000
L41.2 Lymphomatoid papulosis	0.116	0.884	0.000
L41.1 Pityriasis lichenoides chronica	0.116	0.884	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.116	0.884	0.000
L44.9 Papulosquamous disorder, unspecified	0.116	0.884	0.000
L44.8 Other specified papulosquamous disorders	0.116	0.884	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.116	0.884	0.000
L44.3 Lichen ruber moniliformis	0.116	0.884	0.000
L44.2 Lichen striatus	0.116	0.884	0.000
L44.1 Lichen nitidus	0.116	0.884	0.000
L44.0 Pityriasis rubra pilaris	0.116	0.884	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.116	0.884	0.000
E22.1 Hyperprolactinaemia	0.000	0.885	0.115
E29.9 Testicular dysfunction, unspecified	0.000	0.885	0.115
E29.8 Other testicular dysfunction	0.000	0.885	0.115
E29.0 Testicular hyperfunction	0.000	0.885	0.115
E20.8 Other hypoparathyroidism	0.000	0.885	0.114
E20.1 Pseudohypoparathyroidism	0.000	0.885	0.114
E20.0 Idiopathic hypoparathyroidism	0.000	0.885	0.114
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.113	0.887	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.112	0.888	0.000
T43.6 Psychostimulants with abuse potential	0.109	0.891	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.107	0.893	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.107	0.893	0.000
E29.1 Testicular hypofunction	0.000	0.894	0.106
E20.9 Hypoparathyroidism, unspecified	0.000	0.895	0.105
E24.2 Drug-induced Cushing's syndrome	0.000	0.895	0.105
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.895	0.105
E26.9 Hyperaldosteronism, unspecified	0.000	0.895	0.104
E26.8 Other hyperaldosteronism	0.000	0.895	0.104
E26.1 Secondary hyperaldosteronism	0.000	0.895	0.104
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.896	0.104
E22.8 Other hyperfunction of pituitary gland	0.000	0.896	0.104
E24.8 Other Cushing's syndrome	0.000	0.896	0.104
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.896	0.104
E24.3 Ectopic ACTH syndrome	0.000	0.896	0.104
E24.1 Nelson's syndrome	0.000	0.896	0.104
T47.1 Other antacids and anti-gastric-secretion drugs	0.104	0.896	0.000
T36 Poisoning by systemic antibiotics	0.103	0.897	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.103	0.897	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.102	0.898	0.000
E28.9 Ovarian dysfunction, unspecified	0.000	0.900	0.100
E28.8 Other ovarian dysfunction	0.000	0.900	0.100
E28.1 Androgen excess	0.000	0.900	0.100
E28.0 Oestrogen excess	0.000	0.900	0.100
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.100	0.900	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.100	0.900	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.100	0.900	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.100	0.900	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.100	0.900	0.000
T44.0 Anticholinesterase agents	0.100	0.900	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.098	0.901	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.098	0.902	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.098	0.902	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.098	0.902	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.098	0.902	0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.000	0.902	0.098
T43.3 Phenothiazine antipsychotics and neuroleptics	0.098	0.902	0.000
E28.3 Primary ovarian failure	0.000	0.903	0.097
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.097	0.903	0.000
T43.9 Psychotropic drug, unspecified	0.097	0.903	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.097	0.903	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.097	0.903	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.904	0.095
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.905	0.095
T47.4 Other laxatives	0.094	0.906	0.000
E24.0 Pituitary-dependent Cushing's disease	0.000	0.906	0.093
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.093	0.907	0.000
E34.8 Other specified endocrine disorders	0.000	0.907	0.092
E23 Hypofunction and other disorders of pituitary gland	0.000	0.908	0.092
E27.9 Disorder of adrenal gland, unspecified	0.001	0.908	0.092
E24.9 Cushing's syndrome, unspecified	0.000	0.909	0.091
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.086	0.914	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.086	0.914	0.000
T47.7 Emetics	0.086	0.914	0.000
T47.6 Antidiarrhoeal drugs	0.086	0.914	0.000
T47.5 Digestants	0.086	0.914	0.000
T47.3 Saline and osmotic laxatives	0.086	0.914	0.000
T47.2 Stimulant laxatives	0.086	0.914	0.000
T47.0 Histamine H(2)-receptor antagonists	0.086	0.914	0.000
T50.8 Diagnostic agents	0.084	0.916	0.000
T50.7 Analeptics and opioid receptor antagonists	0.084	0.916	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.084	0.916	0.000
T50.5 Appetite depressants	0.084	0.916	0.000
T50.4 Drugs affecting uric acid metabolism	0.084	0.916	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.084	0.916	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.084	0.916	0.000
T50.1 Loop [high-ceiling] diuretics	0.084	0.916	0.000
T50.0 Mineralocorticoids and their antagonists	0.084	0.916	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.084	0.916	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.082	0.918	0.000
E26.0 Primary hyperaldosteronism	0.000	0.918	0.081
T45.0 Antiallergic and antiemetic drugs	0.080	0.920	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.080	0.920	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.080	0.920	0.000
T42.3 Barbiturates	0.080	0.920	0.000
T42.2 Succinimides and oxazolidinediones	0.080	0.920	0.000
T38.1 Thyroid hormones and substitutes	0.080	0.920	0.000
L43 Lichen planus	0.079	0.920	0.001
T36.0 Penicillins	0.079	0.921	0.000
T42.0 Hydantoin derivatives	0.078	0.922	0.000
T38.9 Other and unspecified hormone antagonists	0.077	0.923	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.077	0.923	0.000
T38.7 Androgens and anabolic congeners	0.077	0.923	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.077	0.923	0.000
T38.5 Other oestrogens and progestogens	0.077	0.923	0.000
T38.4 Oral contraceptives	0.077	0.923	0.000
T38.2 Antithyroid drugs	0.077	0.923	0.000
T38.0 Glucocorticoids and synthetic analogues	0.077	0.923	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.077	0.923	0.000
T42.1 Iminostilbenes	0.076	0.924	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.076	0.924	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.924	0.076
K90-K93 Other diseases of the digestive system	0.000	0.924	0.076
T36.9 Systemic antibiotic, unspecified	0.074	0.926	0.000
T36.8 Other systemic antibiotics	0.074	0.926	0.000
T36.7 Antifungal antibiotics, systemically used	0.074	0.926	0.000
T36.6 Rifamycins	0.074	0.926	0.000
T36.5 Aminoglycosides	0.074	0.926	0.000
T36.4 Tetracyclines	0.074	0.926	0.000
T36.3 Macrolides	0.074	0.926	0.000
T36.2 Chloramphenicol group	0.074	0.926	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.074	0.926	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.074	0.926	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.074	0.926	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.073	0.927	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.073	0.927	0.000
T46.7 Peripheral vasodilators	0.073	0.927	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.073	0.927	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.073	0.927	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.073	0.927	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.928	0.072
T45.9 Primarily systemic and haematological agent, unspecified	0.071	0.929	0.000
T45.8 Other primarily systemic and haematological agents	0.071	0.929	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.071	0.929	0.000
T45.6 Fibrinolysis-affecting drugs	0.071	0.929	0.000
T45.4 Iron and its compounds	0.071	0.929	0.000
T45.3 Enzymes, not elsewhere classified	0.071	0.929	0.000
T45.2 Vitamins, not elsewhere classified	0.071	0.929	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.070	0.930	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.070	0.930	0.000
T37.5 Antiviral drugs	0.070	0.930	0.000
T37.4 Anthelminthics	0.070	0.930	0.000
T37.3 Other antiprotozoal drugs	0.070	0.930	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.070	0.930	0.000
T37.1 Antimycobacterial drugs	0.070	0.930	0.000
T37.0 Sulphonamides	0.070	0.930	0.000
T41.5 Therapeutic gases	0.070	0.930	0.000
T41.4 Anaesthetic, unspecified	0.070	0.930	0.000
T41.3 Local anaesthetics	0.070	0.930	0.000
T41.2 Other and unspecified general anaesthetics	0.070	0.930	0.000
T41.1 Intravenous anaesthetics	0.070	0.930	0.000
T41.0 Inhaled anaesthetics	0.070	0.930	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.070	0.930	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.070	0.930	0.000
T48.5 Anti-common-cold drugs	0.070	0.930	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations