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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9296086
log Bayes Factor = 10.3247
Chromosome 6   position 33,110,167  (GRCh37) Explore rs9296086 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.003 0.997
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.007 0.993
E00-E07 Disorders of thyroid gland
0.000 0.013 0.987
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.015 0.985
E10.1 With ketoacidosis
0.000 0.017 0.983
E16 Other disorders of pancreatic internal secretion
0.000 0.020 0.980
E04 Other non-toxic goitre
0.000 0.023 0.977
E16.2 Hypoglycaemia, unspecified
0.000 0.023 0.977
E04.2 Non-toxic multinodular goitre
0.000 0.058 0.942
E06 Thyroiditis
0.000 0.059 0.941
E10.5 With peripheral circulatory complications
0.000 0.070 0.930
E04.1 Non-toxic single thyroid nodule
0.000 0.082 0.918
E50-E64 Other nutritional deficiencies
0.000 0.083 0.917
E10.2 With renal complications
0.000 0.096 0.904
E06.3 Autoimmune thyroiditis
0.000 0.103 0.897
E11 Non-insulin-dependent diabetes mellitus
0.000 0.109 0.891
E10.6 With other specified complications
0.000 0.147 0.853
E53 Deficiency of other B group vitamins
0.000 0.151 0.849
E03 Other hypothyroidism
0.000 0.154 0.846
E10.4 With neurological complications
0.000 0.161 0.839
E11.4 With neurological complications
0.000 0.175 0.825
E55 Vitamin D deficiency
0.000 0.180 0.820
E11.3 With ophthalmic complications
0.000 0.182 0.818
E53.8 Deficiency of other specified B group vitamins
0.000 0.186 0.814
E11.1 With ketoacidosis
0.000 0.204 0.796
E03.9 Hypothyroidism, unspecified
0.000 0.222 0.778
E04.0 Non-toxic diffuse goitre
0.000 0.226 0.774
E55.9 Vitamin D deficiency, unspecified
0.000 0.249 0.751
E10.0 With coma
0.000 0.252 0.748
E14 Unspecified diabetes mellitus
0.000 0.258 0.742
E06.9 Thyroiditis, unspecified
0.000 0.265 0.735
E10.8 With unspecified complications
0.000 0.271 0.729
E10.7 With multiple complications
0.000 0.283 0.717
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.285 0.715
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.292 0.708
E00 Congenital iodine-deficiency syndrome
0.000 0.292 0.708
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.292 0.708
E15 Nondiabetic hypoglycaemic coma
0.000 0.293 0.706
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.297 0.703
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.297 0.703
E16.4 Abnormal secretion of gastrin
0.000 0.297 0.703
E16.3 Increased secretion of glucagon
0.000 0.297 0.703
E04.8 Other specified non-toxic goitre
0.000 0.299 0.701
E11.6 With other specified complications
0.000 0.314 0.686
E06.5 Other chronic thyroiditis
0.000 0.326 0.674
E06.4 Drug-induced thyroiditis
0.000 0.326 0.674
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.326 0.674
E06.1 Subacute thyroiditis
0.000 0.326 0.674
E06.0 Acute thyroiditis
0.000 0.326 0.674
E14.3 With ophthalmic complications
0.000 0.333 0.667
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.342 0.658
E63 Other nutritional deficiencies
0.000 0.342 0.658
E56 Other vitamin deficiencies
0.000 0.342 0.658
E50 Vitamin A deficiency
0.000 0.342 0.658
E60 Dietary zinc deficiency
0.000 0.342 0.658
E59 Dietary selenium deficiency
0.000 0.342 0.658
E58 Dietary calcium deficiency
0.000 0.342 0.658
E54 Ascorbic acid deficiency
0.000 0.342 0.658
E52 Niacin deficiency [pellagra]
0.000 0.342 0.658
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.344 0.656
E11.7 With multiple complications
0.000 0.361 0.639
E51 Thiamine deficiency
0.000 0.372 0.628
E16.1 Other hypoglycaemia
0.000 0.373 0.627
E04.9 Non-toxic goitre, unspecified
0.000 0.374 0.626
E11.0 With coma
0.000 0.391 0.609
E53.1 Pyridoxine deficiency
0.000 0.391 0.609
E53.0 Riboflavin deficiency
0.000 0.391 0.609
E11.8 With unspecified complications
0.000 0.392 0.608
E03.5 Myxoedema coma
0.000 0.393 0.607
E03.4 Atrophy of thyroid (acquired)
0.000 0.393 0.607
E03.3 Postinfectious hypothyroidism
0.000 0.393 0.607
E03.1 Congenital hypothyroidism without goitre
0.000 0.393 0.607
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.393 0.607
E11.2 With renal complications
0.000 0.408 0.592
E55.0 Rickets, active
0.000 0.412 0.588
E14.1 With ketoacidosis
0.000 0.466 0.534
E14.7 With multiple complications
0.000 0.468 0.532
E14.6 With other specified complications
0.000 0.468 0.532
E14.5 With peripheral circulatory complications
0.000 0.468 0.532
E14.2 Withrenal complications
0.000 0.468 0.532
E14.0 With coma
0.000 0.468 0.532
E20-E35 Disorders of other endocrine glands
0.000 0.470 0.530
E13 Other specified diabetes mellitus
0.001 0.478 0.521
E14.8 With unspecified complications
0.000 0.482 0.518
E53.9 Vitamin B deficiency, unspecified
0.000 0.483 0.517
E12.9 Without complications
0.000 0.487 0.512
E12.8 With unspecified complications
0.000 0.487 0.512
E12.7 With multiple complications
0.000 0.487 0.512
E12.6 With other specified complications
0.000 0.487 0.512
E12.5 With peripheral circulatory complications
0.000 0.487 0.512
E12.4 With neurological complications
0.000 0.487 0.512
E12.3 With ophthalmic complications
0.000 0.487 0.512
E12.2 With renal complications
0.000 0.487 0.512
E12.1 With ketoacidosis
0.000 0.487 0.512
E12.0 With coma
0.000 0.487 0.512
E14.4 With neurological complications
0.000 0.489 0.511
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.492 0.507
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.492 0.507
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.492 0.507
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.492 0.507
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.492 0.507
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.492 0.507
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.492 0.507
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.492 0.507
E40-E46 Malnutrition
0.001 0.496 0.503
E65-E68 Obesity and other hyperalimentation
0.000 0.500 0.500
E20 Hypoparathyroidism
0.000 0.512 0.488
E50.9 Vitamin A deficiency, unspecified
0.000 0.528 0.472
E50.8 Other manifestations of vitamin A deficiency
0.000 0.528 0.472
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.528 0.472
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.528 0.472
E50.5 Vitamin A deficiency with night blindness
0.000 0.528 0.472
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.528 0.472
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.528 0.472
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.528 0.472
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.528 0.472
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.528 0.472
E56.9 Vitamin deficiency, unspecified
0.000 0.528 0.472
E56.8 Deficiency of other vitamins
0.000 0.528 0.472
E56.1 Deficiency of vitamin K
0.000 0.528 0.472
E56.0 Deficiency of vitamin E
0.000 0.528 0.472
E63.9 Nutritional deficiency, unspecified
0.000 0.528 0.472
E63.8 Other specified nutritional deficiencies
0.000 0.528 0.472
E63.1 Imbalance of constituents of food intake
0.000 0.528 0.472
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.528 0.472
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.528 0.472
E64.8 Sequelae of other nutritional deficiencies
0.000 0.528 0.472
E64.3 Sequelae of rickets
0.000 0.528 0.472
E64.2 Sequelae of vitamin C deficiency
0.000 0.528 0.472
E64.1 Sequelae of vitamin A deficiency
0.000 0.528 0.472
E64.0 Sequelae of protein-energy malnutrition
0.000 0.528 0.472
E07 Other disorders of thyroid
0.000 0.532 0.468
E27 Other disorders of adrenal gland
0.000 0.536 0.464
E20.9 Hypoparathyroidism, unspecified
0.000 0.542 0.458
E51.9 Thiamine deficiency, unspecified
0.000 0.549 0.450
E51.8 Other manifestations of thiamine deficiency
0.000 0.549 0.450
E51.1 Beriberi
0.000 0.549 0.450
E27.1 Primary adrenocortical insufficiency
0.000 0.550 0.450
E61 Deficiency of other nutrient elements
0.000 0.576 0.424
E51.2 Wernicke's encephalopathy
0.000 0.579 0.421
E03.8 Other specified hypothyroidism
0.000 0.598 0.402
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.620 0.380
E32 Diseases of thymus
0.000 0.620 0.380
E31 Polyglandular dysfunction
0.000 0.620 0.380
E30 Disorders of puberty, not elsewhere classified
0.000 0.620 0.380
E25 Adrenogenital disorders
0.000 0.620 0.380
E13.8 With unspecified complications
0.001 0.626 0.374
E13.7 With multiple complications
0.001 0.626 0.374
E13.6 With other specified complications
0.001 0.626 0.374
E13.5 With peripheral circulatory complications
0.001 0.626 0.374
E13.4 With neurological complications
0.001 0.626 0.374
E13.3 With ophthalmic complications
0.001 0.626 0.374
E13.2 With renal complications
0.001 0.626 0.374
E13.1 With ketoacidosis
0.001 0.626 0.374
E13.0 With coma
0.001 0.626 0.374
E22 Hyperfunction of pituitary gland
0.000 0.630 0.370
E65 Localised adiposity
0.000 0.635 0.365
E44 Protein-energy malnutrition of moderate and mild degree
0.001 0.638 0.361
E45 Retarded development following protein-energy malnutrition
0.001 0.638 0.361
E43 Unspecified severe protein-energy malnutrition
0.001 0.638 0.361
E42 Marasmic kwashiorkor
0.001 0.638 0.361
E41 Nutritional marasmus
0.001 0.638 0.361
E40 Kwashiorkor
0.001 0.638 0.361
E67 Other hyperalimentation
0.000 0.641 0.359
E68 Sequelae of hyperalimentation
0.000 0.641 0.359
E26 Hyperaldosteronism
0.000 0.649 0.350
E20.8 Other hypoparathyroidism
0.000 0.650 0.350
E20.1 Pseudohypoparathyroidism
0.000 0.650 0.350
E20.0 Idiopathic hypoparathyroidism
0.000 0.650 0.350
E28 Ovarian dysfunction
0.000 0.654 0.346
E07.1 Dyshormogenetic goitre
0.000 0.664 0.336
E07.0 Hypersecretion of calcitonin
0.000 0.664 0.336
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.664 0.335
E34 Other endocrine disorders
0.000 0.666 0.334
E27.5 Adrenomedullary hyperfunction
0.000 0.667 0.333
E27.0 Other adrenocortical overactivity
0.000 0.667 0.333
E27.2 Addisonian crisis
0.000 0.674 0.325
E27.9 Disorder of adrenal gland, unspecified
0.000 0.678 0.322
E29 Testicular dysfunction
0.000 0.679 0.321
E07.8 Other specified disorders of thyroid
0.000 0.690 0.309
E14.9 Without complications
0.000 0.693 0.307
E61.9 Deficiency of nutrient element, unspecified
0.000 0.696 0.304
E61.8 Deficiency of other specified nutrient elements
0.000 0.696 0.304
E61.7 Deficiency of multiple nutrient elements
0.000 0.696 0.304
E61.6 Vanadium deficiency
0.000 0.696 0.304
E61.5 Molybdenum deficiency
0.000 0.696 0.304
E61.4 Chromium deficiency
0.000 0.696 0.304
E61.3 Manganese deficiency
0.000 0.696 0.304
E61.0 Copper deficiency
0.000 0.696 0.304
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.696 0.304
E25.9 Adrenogenital disorder, unspecified
0.000 0.727 0.272
E25.8 Other adrenogenital disorders
0.000 0.727 0.272
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.727 0.272
E30.9 Disorder of puberty, unspecified
0.000 0.727 0.272
E30.8 Other disorders of puberty
0.000 0.727 0.272
E30.1 Precocious puberty
0.000 0.727 0.272
E30.0 Delayed puberty
0.000 0.727 0.272
E31.9 Polyglandular dysfunction, unspecified
0.000 0.727 0.272
E31.8 Other polyglandular dysfunction
0.000 0.727 0.272
E31.1 Polyglandular hyperfunction
0.000 0.727 0.272
E31.0 Autoimmune polyglandular failure
0.000 0.727 0.272
E32.9 Disease of thymus, unspecified
0.000 0.727 0.272
E32.8 Other diseases of thymus
0.000 0.727 0.272
E32.1 Abscess of thymus
0.000 0.727 0.272
E32.0 Persistent hyperplasia of thymus
0.000 0.727 0.272
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.727 0.272
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.727 0.272
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.727 0.272
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.732 0.268
E28.3 Primary ovarian failure
0.000 0.733 0.267
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.735 0.265
E22.8 Other hyperfunction of pituitary gland
0.000 0.735 0.265
E24 Cushing's syndrome
0.000 0.738 0.262
E44.1 Mild protein-energy malnutrition
0.001 0.741 0.259
E44.0 Moderate protein-energy malnutrition
0.001 0.741 0.259
E67.8 Other specified hyperalimentation
0.000 0.742 0.257
E67.3 Hypervitaminosis D
0.000 0.742 0.257
E67.2 Megavitamin-B6 syndrome
0.000 0.742 0.257
E67.1 Hypercarotenaemia
0.000 0.742 0.257
E67.0 Hypervitaminosis A
0.000 0.742 0.257
E61.2 Magnesium deficiency
0.001 0.746 0.254
E26.0 Primary hyperaldosteronism
0.000 0.747 0.253
E26.8 Other hyperaldosteronism
0.000 0.748 0.251
E26.1 Secondary hyperaldosteronism
0.000 0.748 0.251
E23 Hypofunction and other disorders of pituitary gland
0.000 0.750 0.250
E11.5 With peripheral circulatory complications
0.001 0.751 0.248
E28.9 Ovarian dysfunction, unspecified
0.000 0.752 0.248
E28.8 Other ovarian dysfunction
0.000 0.752 0.248
E28.1 Androgen excess
0.000 0.752 0.248
E28.0 Oestrogen excess
0.000 0.752 0.248
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.758 0.242
E34.0 Carcinoid syndrome
0.000 0.759 0.241
E22.0 Acromegaly and pituitary gigantism
0.000 0.760 0.240
E34.5 Androgen resistance syndrome
0.000 0.761 0.239
E34.4 Constitutional tall stature
0.000 0.761 0.239
E34.3 Short stature, not elsewhere classified
0.000 0.761 0.239
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.761 0.239
E34.1 Other hypersecretion of intestinal hormones
0.000 0.761 0.239
E29.9 Testicular dysfunction, unspecified
0.000 0.769 0.230
E29.8 Other testicular dysfunction
0.000 0.769 0.230
E29.0 Testicular hyperfunction
0.000 0.769 0.230
E22.1 Hyperprolactinaemia
0.000 0.777 0.222
E27.8 Other specified disorders of adrenal gland
0.000 0.777 0.222
E34.9 Endocrine disorder, unspecified
0.000 0.778 0.222
E26.9 Hyperaldosteronism, unspecified
0.000 0.780 0.220
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.786 0.214
E34.8 Other specified endocrine disorders
0.000 0.786 0.213
E23.6 Other disorders of pituitary gland
0.000 0.798 0.202
E24.8 Other Cushing's syndrome
0.000 0.812 0.188
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.812 0.188
E24.3 Ectopic ACTH syndrome
0.000 0.812 0.188
E24.1 Nelson's syndrome
0.000 0.812 0.188
E23.7 Disorder of pituitary gland, unspecified
0.000 0.813 0.187
E24.2 Drug-induced Cushing's syndrome
0.000 0.814 0.185
E28.2 Polycystic ovarian syndrome
0.000 0.816 0.183
E13.9 Without complications
0.001 0.818 0.181
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.820 0.179
E23.1 Drug-induced hypopituitarism
0.000 0.820 0.179
E61.1 Iron deficiency
0.001 0.825 0.174
E21.4 Other specified disorders of parathyroid gland
0.000 0.826 0.174
E21.2 Other hyperparathyroidism
0.000 0.826 0.174
E29.1 Testicular hypofunction
0.000 0.828 0.172
E21.0 Primary hyperparathyroidism
0.000 0.832 0.168
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.833 0.167
E07.9 Disorder of thyroid, unspecified
0.000 0.842 0.157
E24.9 Cushing's syndrome, unspecified
0.000 0.844 0.156
E05.5 Thyroid crisis or storm
0.000 0.846 0.154
E05.4 Thyrotoxicosis factitia
0.000 0.846 0.154
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.846 0.154
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.846 0.154
E46 Unspecified protein-energy malnutrition
0.001 0.846 0.152
E21.3 Hyperparathyroidism, unspecified
0.000 0.855 0.145
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.863 0.137
E24.0 Pituitary-dependent Cushing's disease
0.001 0.867 0.132
E05.8 Other thyrotoxicosis
0.000 0.867 0.133
E66 Obesity
0.000 0.870 0.130
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.878 0.121
E23.0 Hypopituitarism
0.000 0.899 0.101
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.900 0.099
E23.2 Diabetes insipidus
0.001 0.906 0.093
E66.1 Drug-induced obesity
0.000 0.907 0.093
E66.0 Obesity due to excess calories
0.000 0.915 0.084
E05.9 Thyrotoxicosis, unspecified
0.000 0.923 0.077
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.927 0.073
R20.2 Paraesthesia of skin
0.064 0.936 0.000
E66.8 Other obesity
0.000 0.946 0.054
E70-E90 Metabolic disorders
0.000 0.969 0.031
E11.9 Without complications
0.000 0.972 0.028
N81.2 Incomplete uterovaginal prolapse
0.028 0.972 0.000
R20 Disturbances of skin sensation
0.025 0.975 0.000
H36.0 Diabetic retinopathy
0.000 0.976 0.024
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.977 0.023
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.978 0.022
E77 Disorders of glycoprotein metabolism
0.000 0.978 0.022
E76 Disorders of glycosaminoglycan metabolism
0.000 0.978 0.022
E72 Other disorders of amino-acid metabolism
0.000 0.978 0.022
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.978 0.022
E70 Disorders of aromatic amino-acid metabolism
0.000 0.978 0.022
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.978 0.022
E83 Disorders of mineral metabolism
0.000 0.978 0.022
E79 Disorders of purine and pyrimidine metabolism
0.000 0.978 0.022
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.979 0.021
E84 Cystic fibrosis
0.000 0.979 0.021
R20.3 Hyperaesthesia
0.021 0.979 0.000
E74 Other disorders of carbohydrate metabolism
0.000 0.979 0.021
E88 Other metabolic disorders
0.000 0.980 0.020
E83.4 Disorders of magnesium metabolism
0.000 0.980 0.020
E73 Lactose intolerance
0.000 0.982 0.018
E89.2 Postprocedural hypoparathyroidism
0.000 0.982 0.018
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.982 0.018
R20.1 Hypoaesthesia of skin
0.018 0.982 0.000
E80.6 Other disorders of bilirubin metabolism
0.000 0.983 0.017
E83.1 Disorders of iron metabolism
0.000 0.983 0.017
R20.0 Anaesthesia of skin
0.017 0.983 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.983 0.016
E80.5 Crigler-Najjar syndrome
0.000 0.983 0.016
E80.3 Defects of catalase and peroxydase
0.000 0.983 0.016
E80.2 Other porphyria
0.000 0.983 0.016
E80.1 Porphyria cutanea tarda
0.000 0.983 0.016
E80.0 Hereditary erythropoietic porphyria
0.000 0.983 0.016
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.984 0.016
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.984 0.016
E89.5 Postprocedural testicular hypofunction
0.000 0.984 0.016
E89.1 Postprocedural hypoinsulinaemia
0.000 0.984 0.016
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.984 0.016
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.984 0.016
E70.3 Albinism
0.000 0.984 0.016
E70.2 Disorders of tyrosine metabolism
0.000 0.984 0.016
E70.1 Other hyperphenylalaninaemias
0.000 0.984 0.016
E70.0 Classical phenylketonuria
0.000 0.984 0.016
E71.3 Disorders of fatty-acid metabolism
0.000 0.984 0.016
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.984 0.016
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.984 0.016
E71.0 Maple-syrup-urine disease
0.000 0.984 0.016
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.984 0.016
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.984 0.016
E72.5 Disorders of glycine metabolism
0.000 0.984 0.016
E72.4 Disorders of ornithine metabolism
0.000 0.984 0.016
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.984 0.016
E72.2 Disorders of urea cycle metabolism
0.000 0.984 0.016
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.984 0.016
E72.0 Disorders of amino-acid transport
0.000 0.984 0.016
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.984 0.016
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.984 0.016
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.984 0.016
E76.2 Other mucopolysaccharidoses
0.000 0.984 0.016
E76.1 Mucopolysaccharidosis, type II
0.000 0.984 0.016
E76.0 Mucopolysaccharidosis, type I
0.000 0.984 0.016
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.984 0.016
E77.8 Other disorders of glycoprotein metabolism
0.000 0.984 0.016
E77.1 Defects in glycoprotein degradation
0.000 0.984 0.016
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.984 0.016
E89.3 Postprocedural hypopituitarism
0.000 0.984 0.016
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.984 0.016
E83.8 Other disorders of mineral metabolism
0.000 0.984 0.016
E83.2 Disorders of zinc metabolism
0.000 0.984 0.016
E83.0 Disorders of copper metabolism
0.000 0.984 0.016
E80.4 Gilbert's syndrome
0.000 0.984 0.016
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.984 0.016
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.984 0.016
E79.1 Lesch-Nyhan syndrome
0.000 0.984 0.016
E89.0 Postprocedural hypothyroidism
0.000 0.984 0.016
E89.4 Postprocedural ovarian failure
0.000 0.984 0.016
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.984 0.015
E75.6 Lipid storage disorder, unspecified
0.000 0.985 0.015
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.985 0.015
E75.3 Sphingolipidosis, unspecified
0.000 0.985 0.015
E75.2 Other sphingolipidosis
0.000 0.985 0.015
E75.1 Other gangliosidosis
0.000 0.985 0.015
E75.0 GM2 gangliosidosis
0.000 0.985 0.015
E84.8 Cystic fibrosis with other manifestations
0.000 0.985 0.015
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.985 0.015
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.985 0.015
E85 Amyloidosis
0.000 0.985 0.015
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.985 0.015
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.985 0.015
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.985 0.015
E74.2 Disorders of galactose metabolism
0.000 0.985 0.015
E74.1 Disorders of fructose metabolism
0.000 0.985 0.015
E74.0 Glycogen storage disease
0.000 0.985 0.015
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.985 0.015
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.985 0.015
E75.5 Other lipid storage disorders
0.000 0.986 0.014
E84.9 Cystic fibrosis, unspecified
0.000 0.986 0.014
E88.2 Lipomatosis, not elsewhere classified
0.000 0.986 0.014
R20.8 Other and unspecified disturbances of skin sensation
0.014 0.986 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.986 0.013
E73.8 Other lactose intolerance
0.000 0.986 0.013
E73.1 Secondary lactase deficiency
0.000 0.986 0.013
E73.0 Congenital lactase deficiency
0.000 0.986 0.013
E88.8 Other specified metabolic disorders
0.000 0.987 0.013
M19.97 Arthrosis, unspecified (Ankle and foot)
0.013 0.987 0.000
E83.3 Disorders of phosphorus metabolism
0.000 0.988 0.012
E88.9 Metabolic disorder, unspecified
0.000 0.988 0.012
E88.3 Tumour lysis syndrome
0.000 0.988 0.012
E86 Volume depletion
0.000 0.988 0.012
E85.8 Other amyloidosis
0.000 0.989 0.011
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.989 0.011
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.989 0.011
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.989 0.011
E85.3 Secondary systemic amyloidosis
0.000 0.989 0.011
H36 Retinal disorders in diseases classified elsewhere
0.000 0.989 0.011
E83.5 Disorders of calcium metabolism
0.000 0.989 0.011
Y85.0 Sequelae of motor-vehicle accident
0.000 0.989 0.011
E85.4 Organ-limited amyloidosis
0.000 0.990 0.009
E73.9 Lactose intolerance, unspecified
0.000 0.990 0.009
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.990 0.010
E78.2 Mixed hyperlipidaemia
0.000 0.992 0.008
E78.1 Pure hyperglyceridaemia
0.000 0.992 0.008
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.992 0.008
E78.4 Other hyperlipidaemia
0.000 0.992 0.008
E85.9 Amyloidosis, unspecified
0.001 0.992 0.007
E78.6 Lipoprotein deficiency
0.000 0.993 0.007
E78.3 Hyperchylomicronaemia
0.000 0.993 0.007
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.993 0.007
K91.4 Colostomy and enterostomy malfunction
0.000 0.993 0.007
K90.0 Coeliac disease
0.000 0.993 0.007
T84.0 Mechanical complication of internal joint prosthesis
0.006 0.994 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.006 0.994 0.000
I35.0 Aortic (valve) stenosis
0.005 0.995 0.000
E78.8 Other disorders of lipoprotein metabolism
0.000 0.995 0.005
Z87.8 Personal history of other specified conditions
0.000 0.995 0.005
Y85 Sequelae of transport accidents
0.000 0.995 0.005
M35.0 Sicca syndrome [Sjogren]
0.000 0.995 0.005
L40.9 Psoriasis, unspecified
0.000 0.995 0.005
E66.9 Obesity, unspecified
0.000 0.996 0.004
S52.60 Fracture of lower end of both ulna and radius (closed)
0.000 0.996 0.004
I34.0 Mitral (valve) insufficiency
0.000 0.996 0.004
K14.8 Other diseases of tongue
0.000 0.996 0.004
M35.1 Other overlap syndromes
0.000 0.996 0.004
M35 Other systemic involvement of connective tissue
0.000 0.996 0.004
Y85.9 Sequelae of other and unspecified transport accidents
0.000 0.997 0.003
M35.7 Hypermobility syndrome
0.000 0.997 0.003
Q50.4 Embryonic cyst of Fallopian tube
0.000 0.997 0.003
L40 Psoriasis
0.000 0.997 0.003
S60.9 Superficial injury of wrist and hand, unspecified
0.000 0.997 0.003
Q76 Congenital malformations of spine and bony thorax
0.003 0.997 0.000
L40.8 Other psoriasis
0.000 0.997 0.003
Q44.6 Cystic disease of liver
0.003 0.997 0.000
K37 Unspecified appendicitis
0.000 0.997 0.003
K90 Intestinal malabsorption
0.000 0.997 0.003
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.003 0.997 0.000
Q76.0 Spina bifida occulta
0.003 0.997 0.000
Q66 Congenital deformities of feet
0.003 0.997 0.000
Q66.9 Congenital deformity of feet, unspecified
0.003 0.997 0.000
L40.5 Arthropathic psoriasis
0.000 0.997 0.003
Q76.4 Other congenital malformations of spine, not associated with scoliosis
0.003 0.997 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.997 0.003
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.997 0.003
L40.0 Psoriasis vulgaris
0.000 0.997 0.003
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.003 0.997 0.000
M35.2 Behcet's disease
0.000 0.997 0.003
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.997 0.003
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.997 0.003
M35.5 Multifocal fibrosclerosis
0.000 0.997 0.003
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.997 0.003
Q51.2 Other doubling of uterus
0.003 0.997 0.000
Q65 Congenital deformities of hip
0.003 0.997 0.000
K12.1 Other forms of stomatitis
0.000 0.997 0.003
A63.0 Anogenital (venereal) warts
0.000 0.997 0.003
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.997 0.003
L40.4 Guttate psoriasis
0.000 0.997 0.003
L40.2 Acrodermatitis continua
0.000 0.997 0.003
U80.1 Methicillin resistant agent
0.000 0.997 0.003
Q38-Q45 Other congenital malformations of the digestive system
0.003 0.997 0.000
M35.3 Polymyalgia rheumatica
0.000 0.997 0.003
K90.8 Other intestinal malabsorption
0.000 0.997 0.003
Q65.8 Other congenital deformities of hip
0.003 0.997 0.000
Q66.2 Metatarsus varus
0.002 0.997 0.000
Q66.0 Talipes equinovarus
0.002 0.997 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.997 0.003
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.002 0.997 0.000
M35.8 Other specified systemic involvement of connective tissue
0.000 0.997 0.002
Q76.9 Congenital malformation of bony thorax, unspecified
0.002 0.997 0.000
Q76.8 Other congenital malformations of bony thorax
0.002 0.997 0.000
Q76.7 Congenital malformation of sternum
0.002 0.997 0.000
Q76.6 Other congenital malformations of ribs
0.002 0.997 0.000
Q76.5 Cervical rib
0.002 0.997 0.000
Q76.3 Congenital scoliosis due to congenital bony malformation
0.002 0.997 0.000
Q76.2 Congenital spondylolisthesis
0.002 0.997 0.000
Q76.1 Klippel-Feil syndrome
0.002 0.997 0.000
G60.0 Hereditary motor and sensory neuropathy
0.002 0.997 0.000
Q44.5 Other congenital malformations of bile ducts
0.002 0.997 0.000
Q43 Other congenital malformations of intestine
0.002 0.997 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.001 0.998 0.002
K90.3 Pancreatic steatorrhoea
0.000 0.998 0.002
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.998 0.002
K90.1 Tropical sprue
0.000 0.998 0.002
L40.1 Generalised pustular psoriasis
0.000 0.998 0.002
Q66.3 Other congenital varus deformities of feet
0.002 0.998 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.002 0.998 0.000
Q75 Other congenital malformations of skull and face bones
0.002 0.998 0.000
Q73 Reduction defects of unspecified limb
0.002 0.998 0.000
Q72 Reduction defects of lower limb
0.002 0.998 0.000
Q71 Reduction defects of upper limb
0.002 0.998 0.000
Q70 Syndactyly
0.002 0.998 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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