TreeWAS – Variant ID: rs929843

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M17.9 Gonarthrosis, unspecified	0.104	0.896	0.000
N80.0 Endometriosis of uterus	0.071	0.929	0.000
N80.1 Endometriosis of ovary	0.066	0.934	0.000
N80 Endometriosis	0.066	0.934	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.065	0.935	0.000
Y57 Other and unspecified drugs and medicaments	0.065	0.935	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.065	0.935	0.000
Y57.9 Drug or medicament, unspecified	0.064	0.936	0.000
Y46.2 Hydantoin derivatives	0.060	0.940	0.000
N80.3 Endometriosis of pelvic peritoneum	0.060	0.940	0.000
Y57.5 X-ray contrast media	0.060	0.940	0.000
Y40 Systemic antibiotics	0.058	0.942	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.058	0.942	0.000
N80.5 Endometriosis of intestine	0.057	0.943	0.000
Y40.0 Penicillins	0.057	0.943	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.057	0.943	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.056	0.944	0.000
Y43 Primarily systemic agents	0.055	0.944	0.000
N80.2 Endometriosis of Fallopian tube	0.055	0.945	0.000
Y46.6 Other and unspecified antiepileptics	0.055	0.945	0.000
Y43.4 Immunosuppressive agents	0.053	0.947	0.000
Y59 Other and unspecified vaccines and biological substances	0.053	0.947	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.052	0.948	0.000
Y46.4 Iminostilbenes	0.052	0.948	0.000
Y45.0 Opioids and related analgesics	0.051	0.949	0.000
Y49.2 Other and unspecified antidepressants	0.051	0.949	0.000
Y46.5 Valproic acid	0.051	0.949	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.051	0.949	0.000
M17 Gonarthrosis [arthrosis of knee]	0.050	0.950	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.050	0.950	0.000
Y43.1 Antineoplastic antimetabolites	0.049	0.950	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.049	0.950	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.049	0.951	0.000
Y58 Bacterial vaccines	0.048	0.952	0.000
Y46.7 Anti-Parkinsonism drugs	0.047	0.953	0.000
Y57.7 Vitamins, not elsewhere classified	0.047	0.953	0.000
Y57.4 Pharmaceutical excipients	0.047	0.953	0.000
Y57.3 Alcohol deterrents	0.047	0.953	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.047	0.953	0.000
Y57.1 Lipotropic drugs	0.047	0.953	0.000
Y57.0 Appetite depressants [anorectics]	0.047	0.953	0.000
Y46.8 Antispasticity drugs	0.047	0.953	0.000
Y46.3 Deoxybarbiturates	0.047	0.953	0.000
Y46.1 Oxazolidinediones	0.047	0.953	0.000
Y46.0 Succinimides	0.047	0.953	0.000
M17.1 Other primary gonarthrosis	0.047	0.953	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.046	0.954	0.000
Y48 Anaesthetics and therapeutic gases	0.046	0.954	0.000
Y59.3 Immunoglobulin	0.045	0.955	0.000
Y40.6 Rifamycins	0.045	0.955	0.000
Y45.5 4-Aminophenol derivatives	0.045	0.955	0.000
N80.4 Endometriosis of rectovaginal septum and vagina	0.045	0.955	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.045	0.955	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.045	0.955	0.000
N80.8 Other endometriosis	0.045	0.955	0.000
Y40.7 Antifungal antibiotics, systemically used	0.044	0.956	0.000
Y44 Agents primarily affecting blood constituents	0.044	0.956	0.000
Y41.1 Antimycobacterial drugs	0.043	0.957	0.000
Y57.6 Other diagnostic agents	0.043	0.957	0.000
Y55.4 Expectorants	0.043	0.957	0.000
Y55.0 Oxytocic drugs	0.043	0.957	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.043	0.957	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.043	0.957	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.042	0.958	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.042	0.958	0.000
Y40.2 Chloramphenicol group	0.041	0.958	0.000
Y49.9 Psychotropic drug, unspecified	0.041	0.958	0.000
Y49.7 Psychostimulants with abuse potential	0.041	0.958	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.041	0.958	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.041	0.958	0.000
Y41.0 Sulphonamides	0.041	0.959	0.000
Y40.5 Aminoglycosides	0.041	0.959	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.041	0.959	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.041	0.959	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.041	0.959	0.000
Y55.5 Anticommon cold drugs	0.041	0.959	0.000
Y55.3 Antitussives	0.041	0.959	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.041	0.959	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.041	0.959	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.040	0.959	0.000
Y41.4 Anthelminthics	0.040	0.959	0.000
Y41.3 Other antiprotozoal drugs	0.040	0.959	0.000
Y43.9 Primarily systemic agent, unspecified	0.040	0.960	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.040	0.960	0.000
Y43.6 Enzymes, not elsewhere classified	0.040	0.960	0.000
Y43.5 Acidifying and alkalising agents	0.040	0.960	0.000
Y49.5 Other antipsychotics and neuroleptics	0.040	0.960	0.000
Y43.2 Antineoplastic natural products	0.039	0.961	0.000
Y47.1 Benzodiazepines	0.039	0.961	0.000
Y40.3 Macrolides	0.039	0.961	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.038	0.962	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.038	0.962	0.000
Y59.9 Vaccine or biological substance, unspecified	0.038	0.962	0.000
Y59.8 Other specified vaccines and biological substances	0.038	0.962	0.000
Y59.2 Protozoal vaccines	0.038	0.962	0.000
Y59.1 Rickettsial vaccines	0.038	0.962	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.038	0.962	0.000
N80.6 Endometriosis in cutaneous scar	0.038	0.962	0.000
Y57.8 Other drugs and medicaments	0.037	0.963	0.000
Y41.5 Antiviral drugs	0.037	0.963	0.000
Y45.4 Antirheumatics	0.036	0.964	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.036	0.964	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.036	0.964	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.036	0.964	0.000
Y47.4 Bromine compounds	0.036	0.964	0.000
Y47.3 Paraldehyde	0.036	0.964	0.000
Y47.2 Chloral derivatives	0.036	0.964	0.000
Y47.0 Barbiturates, not elsewhere classified	0.036	0.964	0.000
Y50.9 Central nervous system stimulant, unspecified	0.036	0.964	0.000
Y50.8 Other central nervous system stimulants	0.036	0.964	0.000
Y50.1 Opioid receptor antagonists	0.036	0.964	0.000
Y50.0 Analeptics	0.036	0.964	0.000
Y58.0 BCG vaccine	0.035	0.964	0.000
M17.5 Other secondary gonarthrosis	0.035	0.965	0.000
Y40.4 Tetracyclines	0.035	0.965	0.000
Y48.2 Other and unspecified general anaesthetics	0.035	0.965	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.035	0.965	0.000
Y44.6 Natural blood and blood products	0.035	0.965	0.000
Y56.3 Emollients, demulcents and protectants	0.035	0.965	0.000
Y58.9 Other and unspecified bacterial vaccines	0.034	0.965	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.034	0.965	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.034	0.965	0.000
Y58.5 Diphtheria vaccine	0.034	0.965	0.000
Y58.4 Tetanus vaccine	0.034	0.965	0.000
Y58.3 Plague vaccine	0.034	0.965	0.000
Y58.2 Cholera vaccine	0.034	0.965	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.034	0.965	0.000
Y59.0 Viral vaccines	0.034	0.966	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.033	0.966	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.033	0.966	0.000
M10.99 Gout, unspecified (Site unspecified)	0.033	0.967	0.000
Y56.9 Topical agent, unspecified	0.033	0.967	0.000
Y56.8 Other topical agents	0.033	0.967	0.000
Y56.7 Dental drugs, topically applied	0.033	0.967	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.033	0.967	0.000
Y56.5 Ophthalmological drugs and preparations	0.033	0.967	0.000
Y56.2 Local astringents and local detergents	0.033	0.967	0.000
Y56.1 Antipruritics	0.033	0.967	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.033	0.967	0.000
Y48.5 Therapeutic gases	0.033	0.967	0.000
Y48.1 Parenteral anaesthetics	0.033	0.967	0.000
Y48.0 Inhaled anaesthetics	0.033	0.967	0.000
Y45.1 Salicylates	0.033	0.967	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.032	0.968	0.000
Y43.0 Antiallergic and antiemetic drugs	0.032	0.968	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.032	0.968	0.000
Y44.7 Plasma substitutes	0.032	0.968	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.032	0.968	0.000
Y48.4 Anaesthetic, unspecified	0.032	0.968	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.032	0.968	0.000
Y45.2 Propionic acid derivatives	0.032	0.968	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.031	0.969	0.000
Y44.5 Thrombolytic drugs	0.030	0.969	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.030	0.970	0.000
Y48.3 Local anaesthetics	0.030	0.970	0.000
Y53.2 Stimulant laxatives	0.030	0.970	0.000
Y53.4 Other laxatives	0.030	0.970	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.030	0.970	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.030	0.970	0.000
Y53.7 Emetics	0.030	0.970	0.000
Y53.5 Digestants	0.030	0.970	0.000
Y53.0 Histamine H2-receptor antagonists	0.030	0.970	0.000
Y45.8 Other analgesics and antipyretics	0.029	0.970	0.000
Y53.6 Antidiarrhoeal drugs	0.029	0.970	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.029	0.970	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.029	0.970	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.029	0.970	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.029	0.970	0.000
Y51.0 Anticholinesterase agents	0.029	0.970	0.000
M17.3 Other posttraumatic gonarthrosis	0.029	0.971	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.029	0.971	0.000
Y53.3 Saline and osmotic laxatives	0.028	0.972	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.028	0.972	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.027	0.972	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.026	0.973	0.000
Y54.5 Other diuretics	0.026	0.974	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.025	0.975	0.000
Y52 Agents primarily affecting the cardiovascular system	0.024	0.975	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.024	0.975	0.000
Y40.9 Systemic antibiotic, unspecified	0.024	0.976	0.000
Y54.8 Agents affecting uric acid metabolism	0.024	0.976	0.000
Y54.9 Mineral salts, not elsewhere classified	0.023	0.977	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.023	0.977	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.023	0.977	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.023	0.977	0.000
Y40.8 Other systemic antibiotics	0.023	0.977	0.000
Y54.0 Mineralocorticoids	0.022	0.978	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.022	0.978	0.000
Y54.4 Loop [high-ceiling] diuretics	0.021	0.978	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.021	0.979	0.000
Y54.7 Agents affecting calcification	0.020	0.979	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.020	0.980	0.000
Y42.9 Other and unspecified hormone antagonists	0.019	0.981	0.000
Y42.2 Antithyroid drugs	0.019	0.981	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.018	0.982	0.000
Y52.7 Peripheral vasodilators	0.018	0.982	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.018	0.982	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.017	0.982	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.017	0.982	0.000
Y44.2 Anticoagulants	0.017	0.983	0.000
Y42.4 Oral contraceptives	0.017	0.983	0.000
M17.0 Primary gonarthrosis, bilateral	0.016	0.984	0.000
Y42.1 Thyroid hormones and substitutes	0.016	0.984	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.014	0.985	0.000
M10.9 Gout, unspecified	0.014	0.986	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.014	0.986	0.000
Y52.1 Calcium-channel blockers	0.013	0.987	0.000
Y42.7 Androgens and anabolic congeners	0.013	0.987	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.013	0.987	0.000
H26.9 Cataract, unspecified	0.013	0.987	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.013	0.987	0.000
M10.93 Gout, unspecified (Forearm)	0.012	0.988	0.000
M10.94 Gout, unspecified (Hand)	0.011	0.989	0.000
C71.9 Brain, unspecified	0.000	0.989	0.011
M10.92 Gout, unspecified (Upper arm)	0.011	0.989	0.000
Y54.3 Benzothiadiazine derivatives	0.010	0.989	0.001
M10.90 Gout, unspecified (Multiple sites)	0.011	0.989	0.000
M10.98 Gout, unspecified (Other)	0.010	0.989	0.000
M10.95 Gout, unspecified (Pelvic region and thigh)	0.010	0.989	0.000
M10.91 Gout, unspecified (Shoulder region)	0.010	0.989	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.010	0.989	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.990	0.010
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.010	0.990	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.009	0.990	0.001
I95.1 Orthostatic hypotension	0.010	0.990	0.000
D69 Purpura and other haemorrhagic conditions	0.000	0.990	0.010
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.010	0.990	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.009	0.990	0.001
D69.5 Secondary thrombocytopenia	0.000	0.991	0.009
N80.9 Endometriosis, unspecified	0.009	0.991	0.000
C71 Malignant neoplasm of brain	0.000	0.991	0.009
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.009	0.991	0.000
M10.96 Gout, unspecified (Lower leg)	0.008	0.991	0.000
D69.2 Other nonthrombocytopenic purpura	0.000	0.992	0.008
T83.3 Mechanical complication of intra-uterine contraceptive device	0.008	0.992	0.000
C71.0 Cerebrum, except lobes and ventricles	0.000	0.992	0.008
D69.9 Haemorrhagic condition, unspecified	0.000	0.992	0.008
D69.4 Other primary thrombocytopenia	0.000	0.992	0.008
D69.0 Allergic purpura	0.000	0.992	0.007
D69.8 Other specified haemorrhagic conditions	0.000	0.992	0.007
T83.2 Mechanical complication of graft of urinary organ	0.007	0.993	0.000
C71.2 Temporal lobe	0.000	0.993	0.007
M15-M19 Arthrosis	0.007	0.993	0.000
C71.8 Overlapping lesion of brain	0.000	0.993	0.007
C71.1 Frontal lobe	0.000	0.993	0.007
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.007	0.993	0.000
D69.1 Qualitative platelet defects	0.000	0.993	0.007
C71.6 Cerebellum	0.000	0.993	0.007
C71.5 Cerebral ventricle	0.000	0.993	0.007
M10 Gout	0.007	0.993	0.000
C71.3 Parietal lobe	0.000	0.993	0.006
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.006	0.993	0.000
C71.7 Brain stem	0.000	0.994	0.006
H53.4 Visual field defects	0.000	0.994	0.006
C71.4 Occipital lobe	0.000	0.994	0.006
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.994	0.006
M15 Polyarthrosis	0.006	0.994	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.995	0.005
M18 Arthrosis of first carpometacarpal joint	0.005	0.995	0.000
N75.1 Abscess of Bartholin's gland	0.005	0.995	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.005	0.995	0.000
M10.3 Gout due to impairment of renal function	0.005	0.995	0.000
D69.6 Thrombocytopenia, unspecified	0.000	0.995	0.005
M15.2 Bouchard's nodes (with arthropathy)	0.005	0.995	0.000
M10.4 Other secondary gout	0.005	0.995	0.000
M10.2 Drug-induced gout	0.005	0.995	0.000
M10.1 Lead-induced gout	0.005	0.995	0.000
M15.1 Heberden's nodes (with arthropathy)	0.005	0.995	0.000
Y42.5 Other oestrogens and progestogens	0.005	0.995	0.000
D66 Hereditary factor VIII deficiency	0.000	0.995	0.005
M10.0 Idiopathic gout	0.005	0.995	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.005	0.995	0.000
D67 Hereditary factor IX deficiency	0.000	0.995	0.005
M15.3 Secondary multiple arthrosis	0.005	0.995	0.000
D68 Other coagulation defects	0.000	0.995	0.005
D68.2 Hereditary deficiency of other clotting factors	0.000	0.995	0.005
M15.0 Primary generalised (osteo)arthrosis	0.004	0.995	0.000
D68.0 Von Willebrand's disease	0.000	0.996	0.004
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.996	0.004
M15.9 Polyarthrosis, unspecified	0.004	0.996	0.000
M15.4 Erosive (osteo)arthrosis	0.004	0.996	0.000
M15.8 Other polyarthrosis	0.004	0.996	0.000
M10.39 Gout due to impairment of renal function (Site unspecified)	0.004	0.996	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.004	0.996	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.004	0.996	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.004	0.996	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.004	0.996	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.004	0.996	0.000
M10.38 Gout due to impairment of renal function (Other)	0.004	0.996	0.000
M10.37 Gout due to impairment of renal function (Ankle and foot)	0.004	0.996	0.000
M10.36 Gout due to impairment of renal function (Lower leg)	0.004	0.996	0.000
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)	0.004	0.996	0.000
M10.34 Gout due to impairment of renal function (Hand)	0.004	0.996	0.000
M10.33 Gout due to impairment of renal function (Forearm)	0.004	0.996	0.000
M10.32 Gout due to impairment of renal function (Upper arm)	0.004	0.996	0.000
M10.31 Gout due to impairment of renal function (Shoulder region)	0.004	0.996	0.000
M10.30 Gout due to impairment of renal function (Multiple sites)	0.004	0.996	0.000
M10.00 Idiopathic gout (Multiple sites)	0.004	0.996	0.000
M10.02 Idiopathic gout (Upper arm)	0.004	0.996	0.000
K13.0 Diseases of lips	0.004	0.996	0.000
M10.19 Lead-induced gout (Site unspecified)	0.004	0.996	0.000
M10.18 Lead-induced gout (Other)	0.004	0.996	0.000
M10.17 Lead-induced gout (Ankle and foot)	0.004	0.996	0.000
M10.16 Lead-induced gout (Lower leg)	0.004	0.996	0.000
M10.15 Lead-induced gout (Pelvic region and thigh)	0.004	0.996	0.000
M10.14 Lead-induced gout (Hand)	0.004	0.996	0.000
M10.13 Lead-induced gout (Forearm)	0.004	0.996	0.000
M10.12 Lead-induced gout (Upper arm)	0.004	0.996	0.000
M10.11 Lead-induced gout (Shoulder region)	0.004	0.996	0.000
M10.10 Lead-induced gout (Multiple sites)	0.004	0.996	0.000
M10.29 Drug-induced gout (Site unspecified)	0.004	0.996	0.000
M10.28 Drug-induced gout (Other)	0.004	0.996	0.000
M10.27 Drug-induced gout (Ankle and foot)	0.004	0.996	0.000
M10.26 Drug-induced gout (Lower leg)	0.004	0.996	0.000
M10.25 Drug-induced gout (Pelvic region and thigh)	0.004	0.996	0.000
M10.24 Drug-induced gout (Hand)	0.004	0.996	0.000
M10.23 Drug-induced gout (Forearm)	0.004	0.996	0.000
M10.22 Drug-induced gout (Upper arm)	0.004	0.996	0.000
M10.21 Drug-induced gout (Shoulder region)	0.004	0.996	0.000
M10.20 Drug-induced gout (Multiple sites)	0.004	0.996	0.000
M10.49 Other secondary gout (Site unspecified)	0.004	0.996	0.000
M10.48 Other secondary gout (Other)	0.004	0.996	0.000
M10.47 Other secondary gout (Ankle and foot)	0.004	0.996	0.000
M10.46 Other secondary gout (Lower leg)	0.004	0.996	0.000
M10.45 Other secondary gout (Pelvic region and thigh)	0.004	0.996	0.000
M10.44 Other secondary gout (Hand)	0.004	0.996	0.000
M10.43 Other secondary gout (Forearm)	0.004	0.996	0.000
M10.42 Other secondary gout (Upper arm)	0.004	0.996	0.000
M10.41 Other secondary gout (Shoulder region)	0.004	0.996	0.000
M10.40 Other secondary gout (Multiple sites)	0.004	0.996	0.000
M48.02 Spinal stenosis (Cervical region)	0.004	0.996	0.000
D68.8 Other specified coagulation defects	0.000	0.996	0.004
M10.08 Idiopathic gout (Other)	0.004	0.996	0.000
M10.05 Idiopathic gout (Pelvic region and thigh)	0.004	0.996	0.000
M10.03 Idiopathic gout (Forearm)	0.004	0.996	0.000
M10.01 Idiopathic gout (Shoulder region)	0.004	0.996	0.000
M10.09 Idiopathic gout (Site unspecified)	0.003	0.996	0.000
R20.2 Paraesthesia of skin	0.004	0.996	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.004	0.996	0.000
M19 Other arthrosis	0.004	0.996	0.000
M10.06 Idiopathic gout (Lower leg)	0.003	0.996	0.000
M10.04 Idiopathic gout (Hand)	0.003	0.996	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.003	0.996	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.003	0.996	0.001
H54.0 Blindness, both eyes	0.000	0.996	0.003
M15.00 Primary generalized (osteo)arthrosis, Multiple sites	0.003	0.997	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.003	0.997	0.001
M48.0 Spinal stenosis	0.003	0.997	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.997	0.003
H02.4 Ptosis of eyelid	0.000	0.997	0.003
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.997	0.003
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.997	0.003
M47.96 Spondylosis, unspecified (Lumbar region)	0.003	0.997	0.000
K72.9 Hepatic failure, unspecified	0.003	0.997	0.000
D68.6 Other Thrombophilia	0.000	0.997	0.003
I77.1 Stricture of artery	0.003	0.997	0.000
H33.3 Retinal breaks without detachment	0.000	0.997	0.003
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.997	0.003
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.997	0.003
M15.99 Polyosteoarthritis, unspecified	0.003	0.997	0.000
D68.1 Hereditary factor XI deficiency	0.000	0.997	0.003
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.997	0.003
D68.4 Acquired coagulation factor deficiency	0.000	0.997	0.003
M19.2 Other secondary arthrosis	0.003	0.997	0.000
M19.8 Other specified arthrosis	0.003	0.997	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
N75 Diseases of Bartholin's gland	0.003	0.997	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.003	0.997	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.003	0.997	0.000
D68.5 Primary Thrombophilia	0.000	0.997	0.003
K63.1 Perforation of intestine (nontraumatic)	0.000	0.997	0.003
M48.5 Collapsed vertebra, not elsewhere classified	0.003	0.997	0.000
M48.06 Spinal stenosis (Lumbar region)	0.003	0.997	0.000
B35.3 Tinea pedis	0.000	0.997	0.003
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.003	0.997	0.000
M19.1 Posttraumatic arthrosis of other joints	0.003	0.997	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.997	0.003
M48.03 Spinal stenosis (Cervicothoracic region)	0.003	0.997	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.003	0.997	0.000
L30.9 Dermatitis, unspecified	0.003	0.997	0.000
C83.1 Small cleaved cell (diffuse)	0.000	0.997	0.003
D68.9 Coagulation defect, unspecified	0.000	0.997	0.003
F60.6 Anxious [avoidant] personality disorder	0.000	0.997	0.003
M48 Other spondylopathies	0.003	0.997	0.000
N39.3 Stress incontinence	0.000	0.997	0.003
M48.04 Spinal stenosis (Thoracic region)	0.003	0.997	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.002	0.997	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.003	0.997	0.000
M19.84 Other specified arthrosis (Hand)	0.002	0.997	0.000
B35.1 Tinea unguium	0.000	0.997	0.003
M19.27 Other secondary arthrosis (Ankle and foot)	0.002	0.997	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.002	0.997	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.003	0.997	0.000
N75.8 Other diseases of Bartholin's gland	0.002	0.997	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.002	0.997	0.000
I44.2 Atrioventricular block, complete	0.003	0.997	0.000
N75.9 Disease of Bartholin's gland, unspecified	0.002	0.997	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.002	0.997	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.997	0.002
G55.2 Nerve root and plexus compressions in spondylosis	0.003	0.997	0.000
M19.88 Other specified arthrosis (Other)	0.002	0.998	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.002	0.998	0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.002	0.998	0.000
M19.23 Other secondary arthrosis (Forearm)	0.002	0.998	0.000
M19.87 Other specified arthrosis (Ankle and foot)	0.002	0.998	0.000
M19.29 Other secondary arthrosis (Site unspecified)	0.002	0.998	0.000
M19.28 Other secondary arthrosis (Other)	0.002	0.998	0.000
M19.26 Other secondary arthrosis of other joints-Lower leg	0.002	0.998	0.000
M19.25 Other secondary arthrosis (Pelvic region and thigh)	0.002	0.998	0.000
M19.24 Other secondary arthrosis (Hand)	0.002	0.998	0.000
M19.22 Other secondary arthrosis (Upper arm)	0.002	0.998	0.000
M19.21 Other secondary arthrosis (Shoulder region)	0.002	0.998	0.000
M19.20 Other secondary arthrosis (Multiple sites)	0.002	0.998	0.000
M19.86 Other specified arthrosis (Lower leg)	0.002	0.998	0.000
M19.85 Other specified arthrosis (Pelvic region and thigh)	0.002	0.998	0.000
M19.83 Other specified arthrosis (Forearm)	0.002	0.998	0.000
M19.82 Other specified arthrosis (Upper arm)	0.002	0.998	0.000
M19.80 Other specified arthrosis (Multiple sites)	0.002	0.998	0.000
C83.3 Large cell (diffuse)	0.000	0.998	0.002
Z96.6 Presence of orthopaedic joint implants	0.002	0.998	0.000
C69 Malignant neoplasm of eye and adnexa	0.000	0.998	0.002
M19.81 Other specified arthrosis (Shoulder region)	0.002	0.998	0.000
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.002	0.998	0.000
F60.3 Emotionally unstable personality disorder	0.000	0.998	0.002
Z03.9 Observation for suspected disease or condition, unspecified	0.000	0.998	0.002
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.002	0.998	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.998	0.002
M48.9 Spondylopathy, unspecified	0.002	0.998	0.000
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.002	0.998	0.000
M19.89 Other specified arthrosis (Site unspecified)	0.002	0.998	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.000	0.998	0.002
M19.0 Primary arthrosis of other joints	0.002	0.998	0.000
C70 Malignant neoplasm of meninges	0.000	0.998	0.002
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.002	0.998	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.002	0.998	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.002	0.998	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.002	0.998	0.000
H61.0 Perichondritis of external ear	0.000	0.998	0.002
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
I72.4 Aneurysm of artery of lower extremity	0.000	0.998	0.002
Z22.5 Carrier of viral hepatitis	0.002	0.998	0.000
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.002	0.998	0.000
M19.18 Post-traumatic arthrosis of other joints (Other)	0.002	0.998	0.000
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.002	0.998	0.000
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.002	0.998	0.000
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.002	0.998	0.000
C83.6 Undifferentiated (diffuse)	0.000	0.998	0.002
C83.4 Immunoblastic (diffuse)	0.000	0.998	0.002
C83.2 Mixed small and large cell (diffuse)	0.000	0.998	0.002
H61.2 Impacted cerumen	0.000	0.998	0.002
Z39.0 Care and examination immediately after delivery	0.002	0.998	0.000
B35 Dermatophytosis	0.000	0.998	0.002
M48.4 Fatigue fracture of vertebra	0.002	0.998	0.000
M48.3 Traumatic spondylopathy	0.002	0.998	0.000
M48.2 Kissing spine	0.002	0.998	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.002	0.998	0.000
N70.0 Acute salpingitis and oophoritis	0.002	0.998	0.000
C83.7 Burkitt's tumour	0.000	0.998	0.002
N64.5 Other signs and symptoms in breast	0.002	0.998	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.002	0.998	0.000
C83.5 Lymphoblastic (diffuse)	0.000	0.998	0.002
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.002	0.998	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.002	0.998	0.000
C69.3 Choroid	0.000	0.998	0.002
C69.2 Retina	0.000	0.998	0.002
N77.8 Vulvovaginal ulceration and inflammation in other diseases classified elsewhere	0.002	0.998	0.000
N77.0 Ulceration of vulva in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.002	0.998	0.000
N70 Salpingitis and oophoritis	0.002	0.998	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.002	0.998	0.000
M48.96 Spondylopathy, unspecified (Lumbar region)	0.002	0.998	0.000
M48.92 Spondylopathy, unspecified (Cervical region)	0.002	0.998	0.000
H61 Other disorders of external ear	0.000	0.998	0.002
M48.99 Spondylopathy, unspecified (Site unspecified)	0.002	0.998	0.000
C69.8 Overlapping lesion of eye and adnexa	0.000	0.998	0.002
C69.5 Lachrymal gland and duct	0.000	0.998	0.002
C69.4 Ciliary body	0.000	0.998	0.002
C69.1 Cornea	0.000	0.998	0.002
H61.3 Acquired stenosis of external ear canal	0.000	0.998	0.002
N76.0 Acute vaginitis	0.002	0.998	0.000
F60 Specific personality disorders	0.000	0.998	0.002
H50.0 Convergent concomitant strabismus	0.000	0.998	0.002
O00.1 Tubal pregnancy	0.000	0.998	0.002
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.002	0.998	0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.002	0.998	0.000
M48.94 Spondylopathy, unspecified (Thoracic region)	0.002	0.998	0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.002	0.998	0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.002	0.998	0.000
C69.6 Orbit	0.000	0.998	0.002
C72.9 Central nervous system, unspecified	0.000	0.998	0.002
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.000	0.998	0.002
C72.5 Other and unspecified cranial nerves	0.000	0.998	0.002
C72.4 Acoustic nerve	0.000	0.998	0.002
C72.3 Optic nerve	0.000	0.998	0.002
C72.2 Olfactory nerve	0.000	0.998	0.002
C72.1 Cauda equina	0.000	0.998	0.002
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations