TreeWAS – Variant ID: rs9310862

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K83.0 Cholangitis	0.000	0.936	0.064
K83.1 Obstruction of bile duct	0.000	0.939	0.061
K83 Other diseases of biliary tract	0.000	0.940	0.060
K83.9 Disease of biliary tract, unspecified	0.000	0.945	0.055
K83.3 Fistula of bile duct	0.000	0.957	0.043
K83.2 Perforation of bile duct	0.000	0.957	0.043
K83.5 Biliary cyst	0.000	0.958	0.042
K83.4 Spasm of sphincter of Oddi	0.000	0.960	0.040
I27.2 Other secondary pulmonary hypertension	0.000	0.967	0.033
I27 Other pulmonary heart diseases	0.000	0.967	0.033
K83.8 Other specified diseases of biliary tract	0.000	0.968	0.032
I27.8 Other specified pulmonary heart diseases	0.000	0.968	0.031
I27.9 Pulmonary heart disease, unspecified	0.000	0.969	0.031
I27.0 Primary pulmonary hypertension	0.000	0.972	0.028
I27.1 Kyphoscoliotic heart disease	0.000	0.976	0.024
T40.2 Other opioids	0.022	0.978	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.021	0.979	0.000
T43.2 Other and unspecified antidepressants	0.020	0.980	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.019	0.981	0.000
T42.4 Benzodiazepines	0.018	0.982	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.017	0.983	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.016	0.984	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.016	0.984	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.015	0.985	0.000
T42.0 Hydantoin derivatives	0.015	0.985	0.000
T43.9 Psychotropic drug, unspecified	0.014	0.986	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.014	0.986	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.014	0.986	0.000
T43.6 Psychostimulants with abuse potential	0.013	0.987	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.013	0.987	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.013	0.987	0.000
T42.3 Barbiturates	0.013	0.987	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.013	0.987	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.012	0.988	0.000
T40.8 Lysergide [LSD]	0.012	0.988	0.000
T40.7 Cannabis (derivatives)	0.012	0.988	0.000
T40.3 Methadone	0.012	0.988	0.000
T40.0 Opium	0.012	0.988	0.000
T40.6 Other and unspecified narcotics	0.012	0.988	0.000
T40.1 Heroin	0.012	0.988	0.000
T40.5 Cocaine	0.012	0.988	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.012	0.988	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.012	0.988	0.000
T42.2 Succinimides and oxazolidinediones	0.012	0.988	0.000
T36 Poisoning by systemic antibiotics	0.012	0.988	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.012	0.988	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.012	0.988	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.012	0.988	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.012	0.988	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.011	0.989	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.011	0.989	0.000
O26.8 Other specified pregnancy-related conditions	0.000	0.989	0.011
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.011	0.989	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.011	0.989	0.000
T47.4 Other laxatives	0.010	0.990	0.000
T42.1 Iminostilbenes	0.010	0.990	0.000
T47.2 Stimulant laxatives	0.010	0.990	0.000
T39.1 4-Aminophenol derivatives	0.010	0.990	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.009	0.990	0.000
T37.5 Antiviral drugs	0.009	0.990	0.000
T37.4 Anthelminthics	0.009	0.990	0.000
T37.3 Other antiprotozoal drugs	0.009	0.990	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.009	0.990	0.000
T37.1 Antimycobacterial drugs	0.009	0.990	0.000
T37.0 Sulphonamides	0.009	0.990	0.000
T47.0 Histamine H(2)-receptor antagonists	0.009	0.990	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.009	0.990	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.009	0.991	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.009	0.991	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.009	0.991	0.000
T47.7 Emetics	0.009	0.991	0.000
T47.5 Digestants	0.009	0.991	0.000
T47.3 Saline and osmotic laxatives	0.009	0.991	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.000	0.991	0.009
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.009	0.991	0.000
T38.1 Thyroid hormones and substitutes	0.009	0.991	0.000
T36.9 Systemic antibiotic, unspecified	0.009	0.991	0.000
T36.8 Other systemic antibiotics	0.009	0.991	0.000
T36.7 Antifungal antibiotics, systemically used	0.009	0.991	0.000
T36.6 Rifamycins	0.009	0.991	0.000
T36.5 Aminoglycosides	0.009	0.991	0.000
T36.3 Macrolides	0.009	0.991	0.000
T36.2 Chloramphenicol group	0.009	0.991	0.000
T36.0 Penicillins	0.009	0.991	0.000
T47.6 Antidiarrhoeal drugs	0.009	0.991	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.009	0.991	0.000
T41.5 Therapeutic gases	0.008	0.991	0.000
T41.4 Anaesthetic, unspecified	0.008	0.991	0.000
T41.3 Local anaesthetics	0.008	0.991	0.000
T41.2 Other and unspecified general anaesthetics	0.008	0.991	0.000
T41.1 Intravenous anaesthetics	0.008	0.991	0.000
T41.0 Inhaled anaesthetics	0.008	0.991	0.000
T49.9 Topical agent, unspecified	0.008	0.991	0.000
T49.8 Other topical agents	0.008	0.991	0.000
T49.7 Dental drugs, topically applied	0.008	0.991	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.008	0.991	0.000
T49.5 Ophthalmological drugs and preparations	0.008	0.991	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.008	0.991	0.000
T49.3 Emollients, demulcents and protectants	0.008	0.991	0.000
T49.2 Local astringents and local detergents	0.008	0.991	0.000
T49.1 Antipruritics	0.008	0.991	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.008	0.991	0.000
T48.4 Expectorants	0.008	0.991	0.000
T48.3 Antitussives	0.008	0.991	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.008	0.991	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.008	0.991	0.000
T48.0 Oxytocic drugs	0.008	0.991	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.008	0.991	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.008	0.991	0.000
T36.4 Tetracyclines	0.008	0.991	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.008	0.991	0.000
T39.4 Antirheumatics, not elsewhere classified	0.008	0.992	0.000
T39.2 Pyrazolone derivatives	0.008	0.992	0.000
T38.9 Other and unspecified hormone antagonists	0.008	0.992	0.000
T38.7 Androgens and anabolic congeners	0.008	0.992	0.000
T38.5 Other oestrogens and progestogens	0.008	0.992	0.000
T38.4 Oral contraceptives	0.008	0.992	0.000
T38.2 Antithyroid drugs	0.008	0.992	0.000
T38.0 Glucocorticoids and synthetic analogues	0.008	0.992	0.000
T48.5 Anti-common-cold drugs	0.008	0.992	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.008	0.992	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.008	0.992	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.008	0.992	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.008	0.992	0.000
T50.4 Drugs affecting uric acid metabolism	0.008	0.992	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.007	0.993	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.007	0.993	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.000	0.993	0.007
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.993	0.007
T46 Poisoning by agents primarily affecting the cardiovascular system	0.007	0.993	0.000
C02.9 Tongue, unspecified	0.007	0.993	0.000
T50.7 Analeptics and opioid receptor antagonists	0.007	0.993	0.000
T50.5 Appetite depressants	0.007	0.993	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.007	0.993	0.000
T50.1 Loop [high-ceiling] diuretics	0.007	0.993	0.000
T50.0 Mineralocorticoids and their antagonists	0.007	0.993	0.000
T50.8 Diagnostic agents	0.007	0.993	0.000
H90.5 Sensorineural hearing loss, unspecified	0.007	0.993	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.006	0.993	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.006	0.993	0.000
M66.2 Spontaneous rupture of extensor tendons	0.000	0.993	0.007
H65 Nonsuppurative otitis media	0.007	0.993	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.006	0.994	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.006	0.994	0.000
T45.0 Antiallergic and antiemetic drugs	0.006	0.994	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.006	0.994	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.006	0.994	0.000
T45.8 Other primarily systemic and haematological agents	0.006	0.994	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.006	0.994	0.000
T45.6 Fibrinolysis-affecting drugs	0.006	0.994	0.000
T45.4 Iron and its compounds	0.006	0.994	0.000
T45.3 Enzymes, not elsewhere classified	0.006	0.994	0.000
H65.3 Chronic mucoid otitis media	0.006	0.994	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.005	0.994	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.006	0.994	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.005	0.994	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.005	0.994	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.005	0.994	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.005	0.994	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.005	0.994	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.005	0.994	0.000
T44.0 Anticholinesterase agents	0.005	0.994	0.000
H65.2 Chronic serous otitis media	0.005	0.995	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.005	0.995	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.005	0.995	0.000
T46.7 Peripheral vasodilators	0.005	0.995	0.000
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.000	0.995	0.005
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.005	0.995	0.000
H90.2 Conductive hearing loss, unspecified	0.005	0.995	0.000
T40.4 Other synthetic narcotics	0.005	0.995	0.001
T45.2 Vitamins, not elsewhere classified	0.005	0.995	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.000	0.995	0.005
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.995	0.000
H90 Conductive and sensorineural hearing loss	0.005	0.995	0.000
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.000	0.995	0.005
M66.28 Spontaneous rupture of extensor tendons-Other	0.000	0.995	0.005
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.000	0.995	0.005
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.000	0.995	0.005
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.000	0.995	0.005
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.000	0.995	0.005
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.000	0.995	0.005
O24.9 Diabetes mellitus in pregnancy, unspecified	0.000	0.995	0.005
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.005	0.995	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.005	0.995	0.000
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.000	0.995	0.005
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.005	0.995	0.000
I28 Other diseases of pulmonary vessels	0.000	0.995	0.005
H65.4 Other chronic nonsuppurative otitis media	0.005	0.995	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.000	0.995	0.005
T45.5 Anticoagulants	0.004	0.995	0.000
O24 Diabetes mellitus in pregnancy	0.000	0.995	0.005
H65.1 Other acute nonsuppurative otitis media	0.005	0.995	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.995	0.005
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.995	0.000
T46.1 Calcium-channel blockers	0.004	0.995	0.000
T98 Sequelae of other and unspecified effects of external causes	0.000	0.996	0.004
T46.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.000	0.996	0.004
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.004	0.996	0.000
Z71.3 Dietary counselling and surveillance	0.000	0.996	0.004
T45.1 Antineoplastic and immunosuppressive drugs	0.004	0.996	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.996	0.004
C02 Malignant neoplasm of other and unspecified parts of tongue	0.004	0.996	0.000
O26.5 Maternal hypotension syndrome	0.000	0.996	0.004
M66 Spontaneous rupture of synovium and tendon	0.000	0.996	0.004
O26.4 Herpes gestationis	0.000	0.996	0.004
O26.1 Low weight gain in pregnancy	0.000	0.996	0.004
I49.5 Sick sinus syndrome	0.004	0.996	0.000
O26.2 Pregnancy care of habitual aborter	0.000	0.996	0.004
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.000	0.996	0.004
O20.0 Threatened abortion	0.000	0.996	0.004
T98.1 Sequelae of other and unspecified effects of external causes	0.000	0.996	0.004
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.004	0.996	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.000	0.996	0.004
I28.1 Aneurysm of pulmonary artery	0.000	0.996	0.003
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.996	0.003
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.996	0.004
S92.30 Fracture of metatarsal bone (closed)	0.004	0.996	0.000
O44.1 Placenta praevia with haemorrhage	0.000	0.996	0.004
M66.3 Spontaneous rupture of flexor tendons	0.000	0.996	0.004
O20 Haemorrhage in early pregnancy	0.000	0.996	0.004
O24.3 Pre-existing diabetes mellitus, unspecified	0.000	0.996	0.003
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.000	0.996	0.003
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.000	0.996	0.003
C02.8 Overlapping lesion of tongue	0.003	0.996	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.004	0.996	0.000
C02.2 Ventral surface of tongue	0.003	0.996	0.000
I28.8 Other specified diseases of pulmonary vessels	0.000	0.996	0.003
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.000	0.997	0.003
M66.0 Rupture of popliteal cyst	0.000	0.997	0.003
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.000	0.997	0.003
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.003	0.997	0.000
O26.0 Excessive weight gain in pregnancy	0.000	0.997	0.003
T98.2 Sequelae of certain early complications of trauma	0.000	0.997	0.003
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.000	0.997	0.003
F31 Bipolar affective disorder	0.003	0.997	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
H65.0 Acute serous otitis media	0.003	0.997	0.000
I26 Pulmonary embolism	0.000	0.997	0.003
G00.9 Bacterial meningitis, unspecified	0.000	0.997	0.003
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.997	0.003
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.997	0.003
C02.4 Lingual tonsil	0.003	0.997	0.000
C02.0 Dorsal surface of tongue	0.003	0.997	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.997	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.000	0.997	0.003
M66.1 Rupture of synovium	0.000	0.997	0.003
C02.3 Anterior two-thirds of tongue, part unspecified	0.003	0.997	0.000
M50.0 Cervical disk disorder with myelopathy	0.000	0.997	0.003
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.997	0.003
F31.7 Bipolar affective disorder, currently in remission	0.003	0.997	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.003	0.997	0.000
N18.3 Chronic kidney disease, stage 3	0.000	0.997	0.003
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.003	0.997	0.000
M66.4 Spontaneous rupture of other tendons	0.000	0.997	0.003
O22 Venous complications in pregnancy	0.000	0.997	0.003
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.997	0.003
M66.06 Rupture of popliteal cyst-Lower leg	0.000	0.997	0.003
C02.1 Border of tongue	0.003	0.997	0.000
F31.8 Other bipolar affective disorders	0.003	0.997	0.000
O29 Complications of anaesthesia during pregnancy	0.000	0.997	0.003
O25 Malnutrition in pregnancy	0.000	0.997	0.003
F31.0 Bipolar affective disorder, current episode hypomanic	0.003	0.997	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.000	0.997	0.003
K22.9 Disease of oesophagus, unspecified	0.000	0.997	0.003
M66.39 Spontaneous rupture of flexor tendons (Site unspecified)	0.000	0.997	0.003
M66.38 Spontaneous rupture of flexor tendons (Other)	0.000	0.997	0.003
M66.37 Spontaneous rupture of flexor tendons (Ankle and foot)	0.000	0.997	0.003
M66.35 Spontaneous rupture of flexor tendons (Pelvic region and thigh)	0.000	0.997	0.003
M66.33 Spontaneous rupture of flexor tendons (Forearm)	0.000	0.997	0.003
M66.32 Spontaneous rupture of flexor tendons (Upper arm)	0.000	0.997	0.003
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.000	0.997	0.003
M66.30 Spontaneous rupture of flexor tendons (Multiple sites)	0.000	0.997	0.003
M66.09 Rupture of popliteal cyst-Site unspec	0.000	0.997	0.003
M66.08 Rupture of popliteal cyst-Other	0.000	0.997	0.003
M66.07 Rupture of popliteal cyst-Ankle/foot	0.000	0.997	0.003
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.000	0.997	0.003
M66.04 Rupture of popliteal cyst-Hand	0.000	0.997	0.003
M66.03 Rupture of popliteal cyst-Forearm	0.000	0.997	0.003
M66.02 Rupture of popliteal cyst-Upper arm	0.000	0.997	0.003
M66.01 Rupture of popliteal cyst-Shldr region	0.000	0.997	0.003
M66.00 Rupture of popliteal cyst-Mult sites	0.000	0.997	0.003
O20.8 Other haemorrhage in early pregnancy	0.000	0.997	0.003
M66.36 Spontaneous rupture of flexor tendons (Lower leg)	0.000	0.997	0.003
M66.47 Spontaneous rupture of other tendons (Ankle and foot)	0.000	0.997	0.003
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.997	0.003
T39.0 Salicylates	0.002	0.997	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.997	0.003
G00 Bacterial meningitis, not elsewhere classified	0.000	0.997	0.003
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.997	0.001
T50.9 Other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.000	0.997	0.002
H27.0 Aphakia	0.003	0.997	0.000
M66.19 Rupture of synovium (Site unspecified)	0.000	0.997	0.002
M66.18 Rupture of synovium (Other)	0.000	0.997	0.002
M66.17 Rupture of synovium (Ankle and foot)	0.000	0.997	0.002
M66.16 Rupture of synovium (Lower leg)	0.000	0.997	0.002
M66.15 Rupture of synovium (Pelvic region and thigh)	0.000	0.997	0.002
M66.14 Rupture of synovium (Hand)	0.000	0.997	0.002
M66.13 Rupture of synovium (Forearm)	0.000	0.997	0.002
M66.12 Rupture of synovium (Upper arm)	0.000	0.997	0.002
M66.11 Rupture of synovium (Shoulder region)	0.000	0.997	0.002
M66.10 Rupture of synovium (Multiple sites)	0.000	0.997	0.002
M66.59 Spontaneous rupture of unspecified tendon (Site unspecified)	0.000	0.997	0.002
M66.58 Spontaneous rupture of unspecified tendon (Other)	0.000	0.997	0.002
M66.57 Spontaneous rupture of unspecified tendon (Ankle and foot)	0.000	0.997	0.002
M66.56 Spontaneous rupture of unspecified tendon (Lower leg)	0.000	0.997	0.002
M66.55 Spontaneous rupture of unspecified tendon (Pelvic region and thigh)	0.000	0.997	0.002
M66.54 Spontaneous rupture of unspecified tendon (Hand)	0.000	0.997	0.002
M66.53 Spontaneous rupture of unspecified tendon (Forearm)	0.000	0.997	0.002
M66.52 Spontaneous rupture of unspecified tendon (Upper arm)	0.000	0.997	0.002
M66.51 Spontaneous rupture of unspecified tendon (Shoulder region)	0.000	0.997	0.002
M66.50 Spontaneous rupture of unspecified tendon (Multiple sites)	0.000	0.997	0.002
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.997	0.003
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.997	0.002
M66.49 Spontaneous rupture of other tendons (Site unspecified)	0.000	0.997	0.002
M66.48 Spontaneous rupture of other tendons (Other)	0.000	0.997	0.002
M66.45 Spontaneous rupture of other tendons (Pelvic region and thigh)	0.000	0.997	0.002
M66.44 Spontaneous rupture of other tendons (Hand)	0.000	0.997	0.002
M66.43 Spontaneous rupture of other tendons (Forearm)	0.000	0.997	0.002
M66.42 Spontaneous rupture of other tendons (Upper arm)	0.000	0.997	0.002
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.000	0.997	0.002
M66.40 Spontaneous rupture of other tendons (Multiple sites)	0.000	0.997	0.002
H90.0 Conductive hearing loss, bilateral	0.002	0.997	0.000
O22.9 Venous complication in pregnancy, unspecified	0.000	0.997	0.002
O22.8 Other venous complications in pregnancy	0.000	0.997	0.002
O22.5 Cerebral venous thrombosis in pregnancy	0.000	0.997	0.002
O22.2 Superficial thrombophlebitis in pregnancy	0.000	0.997	0.002
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.997	0.002
G00.1 Pneumococcal meningitis	0.000	0.997	0.002
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.997	0.002
O28 Abnormal findings on antenatal screening of mother	0.000	0.997	0.002
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.998	0.002
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.002	0.998	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.000	0.998	0.002
O29.8 Other complications of anaesthesia during pregnancy	0.000	0.998	0.002
O29.6 Failed or difficult intubation during pregnancy	0.000	0.998	0.002
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.000	0.998	0.002
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.000	0.998	0.002
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.000	0.998	0.002
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.000	0.998	0.002
O29.1 Cardiac complications of anaesthesia during pregnancy	0.000	0.998	0.002
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.000	0.998	0.002
R77.8 Other specified abnormalities of plasma proteins	0.000	0.998	0.002
R57.2 Septic shock	0.002	0.998	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.002	0.998	0.000
R57.9 Shock, unspecified	0.002	0.998	0.000
D34 Benign neoplasm of thyroid gland	0.002	0.998	0.000
G00.2 Streptococcal meningitis	0.000	0.998	0.002
O22.1 Genital varices in pregnancy	0.000	0.998	0.002
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.998	0.002
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.998	0.002
S72.20 Subtrochanteric fracture (closed)	0.002	0.998	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.002	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.998	0.002
F31.9 Bipolar affective disorder, unspecified	0.002	0.998	0.000
O22.4 Haemorrhoids in pregnancy	0.000	0.998	0.002
O23 Infections of genito-urinary tract in pregnancy	0.000	0.998	0.002
G00.8 Other bacterial meningitis	0.000	0.998	0.002
G00.3 Staphylococcal meningitis	0.000	0.998	0.002
G00.0 Haemophilus meningitis	0.000	0.998	0.002
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.000	0.998	0.002
I78.1 Naevus, nonneoplastic	0.002	0.998	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.000	0.998	0.002
R47.0 Dysphasia and aphasia	0.000	0.998	0.002
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.000	0.998	0.002
O28.8 Other abnormal findings on antenatal screening of mother	0.000	0.998	0.002
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.000	0.998	0.002
O28.4 Abnormal radiological finding on antenatal screening of mother	0.000	0.998	0.002
O28.2 Abnormal cytological finding on antenatal screening of mother	0.000	0.998	0.002
H27.8 Other specified disorders of lens	0.002	0.998	0.000
Q27.3 Peripheral arteriovenous malformation	0.002	0.998	0.000
D16.4 Bones of skull and face	0.002	0.998	0.000
L29.8 Other pruritus	0.000	0.998	0.002
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.000	0.998	0.002
Z00.8 Other general examinations	0.000	0.998	0.002
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.000	0.998	0.002
O23.0 Infections of kidney in pregnancy	0.000	0.998	0.002
G06.1 Intraspinal abscess and granuloma	0.000	0.998	0.002
O21 Excessive vomiting in pregnancy	0.000	0.998	0.002
R57 Shock, not elsewhere classified	0.002	0.998	0.000
Z00.6 Examination for normal comparison and control in clinical research programme	0.000	0.998	0.002
H27 Other disorders of lens	0.002	0.998	0.000
K66.8 Other specified disorders of peritoneum	0.000	0.998	0.002
R57.1 Hypovolaemic shock	0.002	0.998	0.000
S92.3 Fracture of metatarsal bone	0.002	0.998	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.000	0.998	0.002
O23.2 Infections of urethra in pregnancy	0.000	0.998	0.002
O23.1 Infections of bladder in pregnancy	0.000	0.998	0.002
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.998	0.002
I87.1 Compression of vein	0.002	0.998	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.002	0.998	0.000
W20.0 Home	0.002	0.998	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.000	0.998	0.002
Q82.8 Other specified congenital malformations of skin	0.000	0.998	0.002
Z00.4 General psychiatric examination, not elsewhere classified	0.000	0.998	0.002
G04 Encephalitis, myelitis and encephalomyelitis	0.000	0.998	0.002
J40 Bronchitis, not specified as acute or chronic	0.002	0.998	0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.000	0.998	0.002
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.000	0.998	0.002
Z00.5 Examination of potential donor of organ and tissue	0.000	0.998	0.002
H27.1 Dislocation of lens	0.002	0.998	0.000
H35.2 Other proliferative retinopathy	0.000	0.998	0.002
G06 Intracranial and intraspinal abscess and granuloma	0.000	0.998	0.002
J84 Other interstitial pulmonary diseases	0.000	0.998	0.002
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.000	0.998	0.002
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.002	0.998	0.000
I31.9 Disease of pericardium, unspecified	0.002	0.998	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.998	0.002
M54.99 Dorsalgia, unspecified (Site unspecified)	0.000	0.998	0.002
O21.8 Other vomiting complicating pregnancy	0.000	0.998	0.001
R57.8 Other shock	0.002	0.998	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.998	0.002
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.998	0.002
F84.5 Asperger's syndrome	0.002	0.998	0.000
O21.9 Vomiting of pregnancy, unspecified	0.000	0.998	0.002
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.000	0.998	0.002
H27.9 Disorder of lens, unspecified	0.002	0.998	0.000
T18.5 Foreign body in anus and rectum	0.002	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.001	0.998	0.000
M05.8 Other seropositive rheumatoid arthritis	0.000	0.998	0.002
N42.8 Other specified disorders of prostate	0.000	0.998	0.002
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.998	0.002
E74.3 Other disorders of intestinal carbohydrate absorption	0.002	0.998	0.000
G06.2 Extradural and subdural abscess, unspecified	0.000	0.998	0.002
H90.3 Sensorineural hearing loss, bilateral	0.001	0.998	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.998	0.002
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.002	0.998	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.000	0.998	0.001
G04.1 Tropical spastic paraplegia	0.000	0.998	0.001
G04.0 Acute disseminated encephalitis	0.000	0.998	0.001
G82.2 Paraplegia, unspecified	0.000	0.998	0.002
O75.3 Other infection during labour	0.002	0.998	0.000
Q66.8 Other congenital deformities of feet	0.000	0.998	0.002
Z00.3 Examination for adolescent development state	0.000	0.998	0.001
Z00.2 Examination for period of rapid growth in childhood	0.000	0.998	0.001
Z00.1 Routine child health examination	0.000	0.998	0.001
E27.9 Disorder of adrenal gland, unspecified	0.002	0.998	0.000
Z00.0 General medical examination	0.000	0.998	0.002
J11.1 Influenza with other respiratory manifestations, virus not identified	0.002	0.998	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.000	0.998	0.001
R57.0 Cardiogenic shock	0.001	0.998	0.000
J84.0 Alveolar and parietoalveolar conditions	0.000	0.998	0.001
K11.9 Disease of salivary gland, unspecified	0.000	0.998	0.001
J84.8 Other specified interstitial pulmonary diseases	0.000	0.998	0.001
M05.2 Rheumatoid vasculitis	0.000	0.998	0.001
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.001	0.998	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.000	0.998	0.001
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.998	0.001
C05.1 Soft palate	0.001	0.999	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.999	0.001
M05.0 Felty's syndrome	0.000	0.999	0.001
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.001	0.999	0.001
G01 Meningitis in bacterial diseases classified elsewhere	0.000	0.999	0.001
O75 Other complications of labour and delivery, not elsewhere classified	0.001	0.999	0.000
Q27 Other congenital malformations of peripheral vascular system	0.001	0.999	0.000
G06.0 Intracranial abscess and granuloma	0.000	0.999	0.001
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.999	0.001
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.001	0.999	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.000	0.999	0.001
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.000	0.999	0.001
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.000	0.999	0.001
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.000	0.999	0.001
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.000	0.999	0.001
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.000	0.999	0.001
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.000	0.999	0.001
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.000	0.999	0.001
M05.1 Rheumatoid lung disease	0.000	0.999	0.001
H70.9 Mastoiditis, unspecified	0.001	0.999	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.999	0.001
M31.3 Wegener's granulomatosis	0.000	0.999	0.001
O75.7 Vaginal delivery following previous Caesarean section	0.001	0.999	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.001	0.999	0.000
R70.0 Elevated erythrocyte sedimentation rate	0.001	0.999	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.000	0.999	0.001
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.000	0.999	0.001
I87.2 Venous insufficiency (chronic) (peripheral)	0.001	0.999	0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.000	0.999	0.001
Z47.8 Other specified orthopaedic follow-up care	0.000	0.999	0.001
M05.20 Rheumatoid vasculitis (Multiple sites)	0.000	0.999	0.001
H70.1 Chronic mastoiditis	0.001	0.999	0.000
H91.3 Deaf mutism, not elsewhere classified	0.001	0.999	0.000
O21.2 Late vomiting of pregnancy	0.000	0.999	0.001
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.999	0.001
I78.0 Hereditary haemorrhagic telangiectasia	0.001	0.999	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.000	0.999	0.001
O21.0 Mild hyperemesis gravidarum	0.000	0.999	0.001
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.000	0.999	0.001
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.999	0.001
O75.9 Complication of labour and delivery, unspecified	0.001	0.999	0.000
G03 Meningitis due to other and unspecified causes	0.000	0.999	0.001
M05.28 Rheumatoid vasculitis (Other)	0.000	0.999	0.001
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.000	0.999	0.001
M05.26 Rheumatoid vasculitis (Lower leg)	0.000	0.999	0.001
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.000	0.999	0.001
M05.24 Rheumatoid vasculitis (Hand)	0.000	0.999	0.001
M05.23 Rheumatoid vasculitis (Forearm)	0.000	0.999	0.001
M05.22 Rheumatoid vasculitis (Upper arm)	0.000	0.999	0.001
M05.21 Rheumatoid vasculitis (Shoulder region)	0.000	0.999	0.001
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.001	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations