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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs933208
log Bayes Factor = 82.7562
Chromosome 6   position 31,506,648  (GRCh37) Explore rs933208 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.001 0.999
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
E14.3 With ophthalmic complications
0.000 0.001 0.999
E14.9 Without complications
0.000 0.002 0.998
Chapter XI Diseases of the digestive system
0.000 0.002 0.998
I25.1 Atherosclerotic heart disease
0.000 0.002 0.998
Chapter VIII Diseases of the ear and mastoid process
0.000 0.002 0.998
K90 Intestinal malabsorption
0.000 0.002 0.998
K90-K93 Other diseases of the digestive system
0.000 0.003 0.997
K70-K77 Diseases of liver
0.000 0.006 0.994
E10.1 With ketoacidosis
0.000 0.007 0.993
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.007 0.993
H36.0 Diabetic retinopathy
0.000 0.008 0.992
H36 Retinal disorders in diseases classified elsewhere
0.000 0.009 0.991
H65-H75 Diseases of middle ear and mastoid
0.000 0.010 0.990
H30-H36 Disorders of choroid and retina
0.000 0.010 0.990
G35-G37 Demyelinating diseases of the central nervous system
0.988 0.012 0.000
E10.4 With neurological complications
0.000 0.013 0.987
E78.0 Pure hypercholesterolaemia
0.000 0.014 0.986
G37 Other demyelinating diseases of central nervous system
0.986 0.014 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.016 0.984
Chapter VII Diseases of the eye and adnexa
0.000 0.016 0.984
L40.5 Arthropathic psoriasis
0.000 0.017 0.983
I24 Other acute ischaemic heart diseases
0.000 0.018 0.982
K74 Fibrosis and cirrhosis of liver
0.000 0.019 0.981
H35 Other retinal disorders
0.000 0.019 0.981
G37.9 Demyelinating disease of central nervous system, unspecified
0.981 0.019 0.000
E70-E90 Metabolic disorders
0.000 0.021 0.979
H60-H62 Diseases of external ear
0.000 0.024 0.976
H66 Suppurative and unspecified otitis media
0.000 0.028 0.972
H35.8 Other specified retinal disorders
0.000 0.028 0.972
H66.3 Other chronic suppurative otitis media
0.000 0.032 0.968
I24.8 Other forms of acute ischaemic heart disease
0.000 0.039 0.961
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.040 0.960
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.041 0.959
H71 Cholesteatoma of middle ear
0.000 0.042 0.958
I25.5 Ischaemic cardiomyopathy
0.000 0.044 0.956
I22 Subsequent myocardial infarction
0.000 0.047 0.953
L43 Lichen planus
0.000 0.048 0.952
K74.6 Other and unspecified cirrhosis of liver
0.000 0.058 0.942
E16 Other disorders of pancreatic internal secretion
0.000 0.071 0.929
H60 Otitis externa
0.000 0.083 0.917
E13 Other specified diabetes mellitus
0.000 0.088 0.912
K50-K52 Noninfective enteritis and colitis
0.000 0.088 0.912
E78.8 Other disorders of lipoprotein metabolism
0.000 0.089 0.911
K52 Other non-infective gastro-enteritis and colitis
0.000 0.095 0.905
H61 Other disorders of external ear
0.000 0.097 0.903
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.099 0.901
I20 Angina pectoris
0.000 0.099 0.901
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.100 0.900
E16.2 Hypoglycaemia, unspecified
0.000 0.102 0.898
K75 Other inflammatory liver diseases
0.000 0.103 0.897
K74.5 Biliary cirrhosis, unspecified
0.000 0.103 0.897
E10.5 With peripheral circulatory complications
0.000 0.103 0.897
L43.9 Lichen planus, unspecified
0.000 0.109 0.891
I20.9 Angina pectoris, unspecified
0.000 0.110 0.890
H53-H54 Visual disturbances and blindness
0.000 0.113 0.887
E10.8 With unspecified complications
0.000 0.114 0.886
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.115 0.885
E11.6 With other specified complications
0.000 0.116 0.884
I25.2 Old myocardial infarction
0.000 0.123 0.877
E78.2 Mixed hyperlipidaemia
0.000 0.124 0.876
G37.8 Other specified demyelinating diseases of central nervous system
0.875 0.125 0.000
K60.2 Anal fissure, unspecified
0.000 0.126 0.874
E10.2 With renal complications
0.000 0.129 0.871
K60 Fissure and fistula of anal and rectal regions
0.000 0.138 0.862
E10.0 With coma
0.000 0.141 0.859
H74 Other disorders of middle ear and mastoid
0.000 0.142 0.858
K55-K64 Other diseases of intestines
0.000 0.143 0.857
E00-E07 Disorders of thyroid gland
0.000 0.148 0.852
E13.9 Without complications
0.000 0.151 0.849
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.152 0.848
E11.3 With ophthalmic complications
0.000 0.155 0.845
E11.0 With coma
0.000 0.158 0.842
I11 Hypertensive heart disease
0.000 0.158 0.842
H35.2 Other proliferative retinopathy
0.000 0.160 0.840
K75.4 Autoimmune hepatitis
0.000 0.166 0.834
J45 Asthma
0.000 0.171 0.828
E03 Other hypothyroidism
0.000 0.175 0.825
K73 Chronic hepatitis, not elsewhere classified
0.000 0.175 0.825
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.176 0.824
K76 Other diseases of liver
0.000 0.177 0.823
K74.3 Primary biliary cirrhosis
0.000 0.183 0.817
L42 Pityriasis rosea
0.000 0.183 0.817
I15 Secondary hypertension
0.000 0.187 0.813
E03.9 Hypothyroidism, unspecified
0.000 0.188 0.812
E14.8 With unspecified complications
0.000 0.189 0.811
L50-L54 Urticaria and erythema
0.000 0.191 0.808
K58 Irritable bowel syndrome
0.000 0.194 0.806
L43.8 Other lichen planus
0.000 0.195 0.805
H61.1 Non-infective disorders of pinna
0.000 0.198 0.802
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.206 0.794
L40.8 Other psoriasis
0.000 0.207 0.793
L40.1 Generalised pustular psoriasis
0.000 0.209 0.791
H35.0 Background retinopathy and retinal vascular changes
0.000 0.212 0.788
H61.3 Acquired stenosis of external ear canal
0.000 0.213 0.787
E11.1 With ketoacidosis
0.000 0.214 0.786
H60.3 Other infective otitis externa
0.000 0.214 0.786
K52.1 Toxic gastro-enteritis and colitis
0.000 0.215 0.785
E74 Other disorders of carbohydrate metabolism
0.000 0.218 0.782
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.219 0.781
E10.6 With other specified complications
0.000 0.220 0.780
E14.6 With other specified complications
0.000 0.222 0.778
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.222 0.778
J40-J47 Chronic lower respiratory diseases
0.000 0.223 0.777
H35.5 Hereditary retinal dystrophy
0.000 0.223 0.777
I23 Certain current complications following acute myocardial infarction
0.000 0.223 0.776
E11.2 With renal complications
0.000 0.227 0.773
Chapter X Diseases of the respiratory system
0.000 0.229 0.771
H35.7 Separation of retinal layers
0.000 0.230 0.770
K60.0 Acute anal fissure
0.000 0.231 0.769
K76.9 Liver disease, unspecified
0.000 0.234 0.766
H54 Blindness and low vision
0.000 0.237 0.763
K75.8 Other specified inflammatory liver diseases
0.000 0.237 0.763
H90-H95 Other disorders of ear
0.000 0.237 0.763
K72 Hepatic failure, not elsewhere classified
0.000 0.238 0.762
E78.6 Lipoprotein deficiency
0.000 0.239 0.761
H74.4 Polyp of middle ear
0.000 0.243 0.757
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.246 0.754
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.247 0.753
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.250 0.750
H66.1 Chronic tubotympanic suppurative otitis media
0.000 0.250 0.750
E14.1 With ketoacidosis
0.000 0.250 0.750
E16.1 Other hypoglycaemia
0.000 0.251 0.749
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.746 0.254 0.000
H53 Visual disturbances
0.000 0.255 0.745
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.256 0.744
H43-H45 Disorders of vitreous body and globe
0.000 0.257 0.743
K90.8 Other intestinal malabsorption
0.000 0.257 0.743
H34 Retinal vascular occlusions
0.000 0.262 0.738
L40.3 Pustulosis palmaris et plantaris
0.000 0.262 0.737
E11.4 With neurological complications
0.000 0.263 0.737
H54.9 Unspecified visual impairment (binocular)
0.000 0.263 0.737
H74.9 Disorder of middle ear and mastoid, unspecified
0.000 0.268 0.732
H60.4 Cholesteatoma of external ear
0.000 0.269 0.731
H61.9 Disorder of external ear, unspecified
0.000 0.270 0.730
K86 Other diseases of pancreas
0.000 0.271 0.729
K83 Other diseases of biliary tract
0.000 0.272 0.728
H61.2 Impacted cerumen
0.000 0.272 0.728
E85 Amyloidosis
0.000 0.273 0.727
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.274 0.726
H72 Perforation of tympanic membrane
0.000 0.274 0.726
H35.6 Retinal haemorrhage
0.000 0.277 0.723
H66.4 Suppurative otitis media, unspecified
0.000 0.278 0.722
H60.9 Otitis externa, unspecified
0.000 0.278 0.722
K83.0 Cholangitis
0.000 0.280 0.720
E14.4 With neurological complications
0.000 0.280 0.719
K73.9 Chronic hepatitis, unspecified
0.000 0.282 0.717
L10-L14 Bullous disorders
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.717
G36 Other acute disseminated demyelination
0.717 0.283 0.000
J43 Emphysema
0.000 0.283 0.717
H60.5 Acute otitis externa, non-infective
0.000 0.283 0.716
L44 Other papulosquamous disorders
0.000 0.284 0.716
L41 Parapsoriasis
0.000 0.284 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.716
K90.3 Pancreatic steatorrhoea
0.000 0.285 0.715
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.285 0.715
K90.1 Tropical sprue
0.000 0.285 0.715
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.285 0.714
K77 Liver disorders in diseases classified elsewhere
0.000 0.288 0.712
I25.3 Aneurysm of heart
0.000 0.289 0.711
H90 Conductive and sensorineural hearing loss
0.000 0.289 0.711
H31 Other disorders of choroid
0.000 0.289 0.710
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.290 0.710
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.290 0.710
H68 Eustachian salpingitis and obstruction
0.000 0.290 0.710
H67 Otitis media in diseases classified elsewhere
0.000 0.290 0.710
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.290 0.710
K71 Toxic liver disease
0.000 0.292 0.708
E14.5 With peripheral circulatory complications
0.000 0.293 0.707
G37.5 Concentric sclerosis [Balo]
0.707 0.293 0.000
G37.4 Subacute necrotising myelitis
0.707 0.293 0.000
G37.2 Central pontine myelinolysis
0.707 0.293 0.000
G37.1 Central demyelination of corpus callosum
0.707 0.293 0.000
G37.0 Diffuse sclerosis
0.707 0.293 0.000
K60.5 Anorectal fistula
0.000 0.293 0.707
E78.3 Hyperchylomicronaemia
0.000 0.294 0.706
H53.1 Subjective visual disturbances
0.000 0.295 0.705
E79 Disorders of purine and pyrimidine metabolism
0.000 0.295 0.705
H70 Mastoiditis and related conditions
0.000 0.296 0.704
K74.4 Secondary biliary cirrhosis
0.000 0.296 0.704
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.296 0.704
K74.1 Hepatic sclerosis
0.000 0.296 0.704
H35.1 Retinopathy of prematurity
0.000 0.297 0.703
E77 Disorders of glycoprotein metabolism
0.000 0.298 0.702
E76 Disorders of glycosaminoglycan metabolism
0.000 0.298 0.702
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.298 0.702
E70 Disorders of aromatic amino-acid metabolism
0.000 0.298 0.702
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.298 0.702
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.300 0.700
E78.5 Hyperlipidaemia, unspecified
0.000 0.301 0.699
I25.4 Coronary artery aneurysm
0.000 0.304 0.696
H60.1 Cellulitis of external ear
0.000 0.309 0.691
E88 Other metabolic disorders
0.000 0.310 0.690
E15 Nondiabetic hypoglycaemic coma
0.000 0.312 0.687
H66.0 Acute suppurative otitis media
0.000 0.313 0.687
H60.8 Other otitis externa
0.000 0.314 0.686
H74.8 Other specified disorders of middle ear and mastoid
0.000 0.315 0.685
K86.1 Other chronic pancreatitis
0.000 0.316 0.684
L43.3 Subacute (active) lichen planus
0.000 0.317 0.683
L43.2 Lichenoid drug reaction
0.000 0.317 0.683
L43.1 Bullous lichen planus
0.000 0.317 0.683
L43.0 Hypertrophic lichen planus
0.000 0.317 0.683
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.318 0.682
H30 Chorioretinal inflammation
0.000 0.319 0.681
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.321 0.679
H53.8 Other visual disturbances
0.000 0.323 0.677
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.324 0.676
L52 Erythema nodosum
0.000 0.327 0.673
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.328 0.672
H90.5 Sensorineural hearing loss, unspecified
0.000 0.328 0.672
E72 Other disorders of amino-acid metabolism
0.000 0.331 0.669
K90.9 Intestinal malabsorption, unspecified
0.000 0.332 0.668
K60.4 Rectal fistula
0.000 0.333 0.667
H35.4 Peripheral retinal degeneration
0.000 0.333 0.667
E78.1 Pure hyperglyceridaemia
0.000 0.333 0.666
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.334 0.666
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.334 0.666
E16.4 Abnormal secretion of gastrin
0.000 0.334 0.666
E16.3 Increased secretion of glucagon
0.000 0.334 0.666
H60.0 Abscess of external ear
0.000 0.339 0.661
H60.2 Malignant otitis externa
0.000 0.342 0.658
E84 Cystic fibrosis
0.000 0.343 0.657
H73 Other disorders of tympanic membrane
0.000 0.344 0.656
E13.8 With unspecified complications
0.000 0.346 0.654
E13.7 With multiple complications
0.000 0.346 0.654
E13.6 With other specified complications
0.000 0.346 0.654
E13.5 With peripheral circulatory complications
0.000 0.346 0.654
E13.4 With neurological complications
0.000 0.346 0.654
E13.3 With ophthalmic complications
0.000 0.346 0.654
E13.2 With renal complications
0.000 0.346 0.654
E13.1 With ketoacidosis
0.000 0.346 0.654
E13.0 With coma
0.000 0.346 0.654
H47 Other disorders of optic [2nd] nerve and visual pathways
0.000 0.346 0.654
J43.9 Emphysema, unspecified
0.000 0.347 0.653
I15.1 Hypertension secondary to other renal disorders
0.000 0.347 0.653
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.347 0.653
H43 Disorders of vitreous body
0.000 0.348 0.652
H55-H59 Other disorders of eye and adnexa
0.000 0.351 0.649
E05.9 Thyrotoxicosis, unspecified
0.000 0.353 0.647
K86.2 Cyst of pancreas
0.000 0.354 0.646
E11.5 With peripheral circulatory complications
0.000 0.354 0.645
I12 Hypertensive renal disease
0.000 0.355 0.645
H54.7 Unspecified visual loss
0.000 0.356 0.644
K75.2 Nonspecific reactive hepatitis
0.000 0.357 0.643
K75.1 Phlebitis of portal vein
0.000 0.357 0.643
K76.0 Fatty (change of) liver, not elsewhere classified
0.000 0.357 0.643
K76.8 Other specified diseases of liver
0.000 0.357 0.643
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.360 0.640
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.360 0.640
I20.0 Unstable angina
0.000 0.360 0.640
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.362 0.638
K74.0 Hepatic fibrosis
0.000 0.362 0.638
L40.0 Psoriasis vulgaris
0.000 0.370 0.630
L51 Erythema multiforme
0.000 0.370 0.630
H74.2 Discontinuity and dislocation of ear ossicles
0.000 0.371 0.629
K72.9 Hepatic failure, unspecified
0.000 0.373 0.627
H35.9 Retinal disorder, unspecified
0.000 0.374 0.626
J46 Status asthmaticus
0.000 0.375 0.625
J60-J70 Lung diseases due to external agents
0.000 0.377 0.623
E78.4 Other hyperlipidaemia
0.000 0.377 0.623
L50 Urticaria
0.000 0.378 0.622
E40-E46 Malnutrition
0.000 0.378 0.622
H72.0 Central perforation of tympanic membrane
0.000 0.379 0.621
H92 Otalgia and effusion of ear
0.000 0.383 0.617
I23.8 Other current complications following acute myocardial infarction
0.000 0.384 0.616
E50-E64 Other nutritional deficiencies
0.000 0.384 0.616
I24.1 Dressler's syndrome
0.000 0.385 0.615
H34.8 Other retinal vascular occlusions
0.000 0.385 0.615
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.386 0.614
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.389 0.611
E00 Congenital iodine-deficiency syndrome
0.000 0.389 0.611
I15.9 Seconday hypertension, unspecified
0.000 0.396 0.604
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.396 0.604
H66.2 Chronic atticoantral suppurative otitis media
0.000 0.397 0.602
I15.0 Renovascular hypertension
0.000 0.398 0.602
E88.2 Lipomatosis, not elsewhere classified
0.000 0.399 0.601
H72.2 Other marginal perforations of tympanic membrane
0.000 0.401 0.599
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.401 0.599
J42 Unspecified chronic bronchitis
0.000 0.402 0.598
H53.0 Amblyopia ex anopsia
0.000 0.405 0.595
J45.1 Nonallergic asthma
0.000 0.406 0.594
J90-J94 Other diseases of pleura
0.000 0.407 0.593
L13 Other bullous disorders
0.000 0.407 0.593
E03.5 Myxoedema coma
0.000 0.408 0.591
E03.4 Atrophy of thyroid (acquired)
0.000 0.408 0.591
E03.3 Postinfectious hypothyroidism
0.000 0.408 0.591
E03.1 Congenital hypothyroidism without goitre
0.000 0.408 0.591
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.408 0.591
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.408 0.591
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.408 0.591
K76.5 Hepatic veno-occlusive disease
0.000 0.410 0.590
K76.4 Peliosis hepatis
0.000 0.410 0.590
K76.3 Infarction of liver
0.000 0.410 0.590
K76.2 Central haemorrhagic necrosis of liver
0.000 0.410 0.590
E83.1 Disorders of iron metabolism
0.589 0.410 0.000
K75.9 Inflammatory liver disease, unspecified
0.000 0.411 0.589
E85.9 Amyloidosis, unspecified
0.000 0.414 0.586
H47.3 Other disorders of optic disk
0.000 0.414 0.586
K86.3 Pseudocyst of pancreas
0.000 0.416 0.584
J92 Pleural plaque
0.000 0.417 0.583
I15.8 Other secondary hypertension
0.000 0.417 0.583
I15.2 Hypertension secondary to endocrine disorders
0.000 0.417 0.583
K55 Vascular disorders of intestine
0.000 0.417 0.583
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.418 0.582
E89.3 Postprocedural hypopituitarism
0.000 0.419 0.581
L54 Erythema in diseases classified elsewhere
0.000 0.420 0.580
H90.2 Conductive hearing loss, unspecified
0.000 0.424 0.576
H72.8 Other perforations of tympanic membrane
0.000 0.428 0.572
J92.9 Pleural plaque without asbestos
0.000 0.430 0.570
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.432 0.568
H55 Nystagmus and other irregular eye movements
0.000 0.432 0.568
J43.2 Centrilobular emphysema
0.000 0.432 0.568
J69 Pneumonitis due to solids and liquids
0.000 0.432 0.568
I22.8 Subsequent myocardial infarction of other sites
0.000 0.433 0.567
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.433 0.567
H43.3 Other vitreous opacities
0.000 0.434 0.566
H92.1 Otorrhoea
0.000 0.438 0.562
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.439 0.560
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.439 0.560
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.439 0.560
E74.2 Disorders of galactose metabolism
0.000 0.439 0.560
E74.1 Disorders of fructose metabolism
0.000 0.439 0.560
E74.0 Glycogen storage disease
0.000 0.439 0.560
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.440 0.560
H90.3 Sensorineural hearing loss, bilateral
0.000 0.442 0.558
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.443 0.557
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.443 0.557
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.443 0.557
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.443 0.557
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.443 0.557
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.443 0.557
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.443 0.557
K83.3 Fistula of bile duct
0.000 0.444 0.556
E07 Other disorders of thyroid
0.000 0.447 0.553
H43.2 Crystalline deposits in vitreous body
0.000 0.450 0.550
K75.0 Abscess of liver
0.000 0.451 0.548
H54.3 Unqualified visual loss, both eyes
0.000 0.453 0.547
H54.2 Low vision, both eyes
0.000 0.453 0.547
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.453 0.547
H94 Other disorders of ear in diseases classified elsewhere
0.000 0.453 0.547
I12.9 Hypertensive renal disease without renal failure
0.000 0.453 0.547
K72.1 Chronic hepatic failure
0.000 0.454 0.546
H61.8 Other specified disorders of external ear
0.000 0.455 0.545
E75.5 Other lipid storage disorders
0.000 0.455 0.544
K81 Cholecystitis
0.000 0.456 0.544
H31.1 Choroidal degeneration
0.000 0.457 0.543
H54.0 Blindness, both eyes
0.000 0.458 0.542
H43.9 Disorder of vitreous body, unspecified
0.000 0.458 0.542
E73 Lactose intolerance
0.000 0.458 0.542
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.000 0.462 0.538
H74.1 Adhesive middle ear disease
0.000 0.463 0.537
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.464 0.536
K55.8 Other vascular disorders of intestine
0.000 0.465 0.535
H47.2 Optic atrophy
0.000 0.465 0.535
H53.6 Night blindness
0.000 0.466 0.534
H53.5 Colour vision deficiencies
0.000 0.466 0.534
H53.3 Other disorders of binocular vision
0.000 0.466 0.534
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.466 0.534
E05.5 Thyroid crisis or storm
0.000 0.466 0.533
E05.4 Thyrotoxicosis factitia
0.000 0.466 0.533
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.466 0.533
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.466 0.533
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.467 0.533
H31.0 Chorioretinal scars
0.000 0.468 0.532
J69.0 Pneumonitis due to food and vomit
0.000 0.468 0.532
H34.9 Retinal vascular occlusion, unspecified
0.000 0.469 0.531
H34.0 Transient retinal artery occlusion
0.000 0.471 0.529
H73.9 Disorder of tympanic membrane, unspecified
0.000 0.471 0.529
E65-E68 Obesity and other hyperalimentation
0.000 0.471 0.529
H70.1 Chronic mastoiditis
0.000 0.472 0.528
J43.8 Other emphysema
0.000 0.472 0.527
E88.3 Tumour lysis syndrome
0.000 0.474 0.526
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.475 0.525
J45.8 Mixed asthma
0.000 0.476 0.524
E61 Deficiency of other nutrient elements
0.000 0.476 0.524
G36.0 Neuromyelitis optica [Devic]
0.522 0.478 0.000
E85.3 Secondary systemic amyloidosis
0.000 0.478 0.522
K83.5 Biliary cyst
0.000 0.478 0.522
K83.2 Perforation of bile duct
0.000 0.478 0.522
E85.8 Other amyloidosis
0.000 0.478 0.521
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.478 0.521
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.478 0.521
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.478 0.521
J41 Simple and mucopurulent chronic bronchitis
0.000 0.479 0.521
E75.6 Lipid storage disorder, unspecified
0.000 0.479 0.521
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.479 0.521
E75.3 Sphingolipidosis, unspecified
0.000 0.479 0.521
E75.2 Other sphingolipidosis
0.000 0.479 0.521
E75.1 Other gangliosidosis
0.000 0.479 0.521
E75.0 GM2 gangliosidosis
0.000 0.479 0.521
H74.3 Other acquired abnormalities of ear ossicles
0.000 0.481 0.519
K76.7 Hepatorenal syndrome
0.000 0.484 0.516
K83.4 Spasm of sphincter of Oddi
0.000 0.484 0.516
L10 Pemphigus
0.000 0.485 0.514
L14 Bullous disorders in diseases classified elsewhere
0.000 0.485 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
P90-P96 Other disorders originating in the perinatal period
0.000 0.486 0.514
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.000 0.486 0.514
P75-P78 Digestive system disorders of fetus and newborn
0.000 0.486 0.514
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.000 0.486 0.514
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.000 0.486 0.514
P35-P39 Infections specific to the perinatal period
0.000 0.486 0.514
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.000 0.486 0.514
P10-P15 Birth trauma
0.000 0.486 0.514
P05-P08 Disorders related to length of gestation and fetal growth
0.000 0.486 0.514
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.000 0.486 0.514
I02 Rheumatic chorea
0.000 0.486 0.514
I01 Rheumatic fever with heart involvement
0.000 0.486 0.514
I00 Rheumatic fever without mention of heart involvement
0.000 0.486 0.514
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.486 0.514
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.486 0.514
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.486 0.514
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.486 0.514
G36.9 Acute disseminated demyelination, unspecified
0.514 0.486 0.000
G36.8 Other specified acute disseminated demyelination
0.514 0.486 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.514 0.486 0.000
J43.1 Panlobular emphysema
0.000 0.486 0.514
J43.0 MacLeod's syndrome
0.000 0.486 0.514
E83 Disorders of mineral metabolism
0.481 0.486 0.033
L41.9 Parapsoriasis, unspecified
0.000 0.486 0.513
L41.8 Other parapsoriasis
0.000 0.486 0.513
L41.5 Retiform parapsoriasis
0.000 0.486 0.513
L41.4 Large plaque parapsoriasis
0.000 0.486 0.513
L41.3 Small plaque parapsoriasis
0.000 0.486 0.513
L41.2 Lymphomatoid papulosis
0.000 0.486 0.513
L41.1 Pityriasis lichenoides chronica
0.000 0.486 0.513
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.486 0.513
L44.9 Papulosquamous disorder, unspecified
0.000 0.486 0.513
L44.8 Other specified papulosquamous disorders
0.000 0.486 0.513
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.486 0.513
L44.3 Lichen ruber moniliformis
0.000 0.486 0.513
L44.2 Lichen striatus
0.000 0.486 0.513
L44.1 Lichen nitidus
0.000 0.486 0.513
L44.0 Pityriasis rubra pilaris
0.000 0.486 0.513
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.488 0.512
K93.1 Megacolon in Chagas' disease
0.000 0.488 0.512
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.488 0.512
J85 Abscess of lung and mediastinum
0.000 0.489 0.511
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.489 0.511
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.489 0.511
H31.9 Disorder of choroid, unspecified
0.000 0.490 0.509
H31.4 Choroidal detachment
0.000 0.490 0.509
H31.2 Hereditary choroidal dystrophy
0.000 0.490 0.509
H67.8 Otitis media in other diseases classified elsewhere
0.000 0.491 0.509
H67.1 Otitis media in viral diseases classified elsewhere
0.000 0.491 0.509
H67.0 Otitis media in bacterial diseases classified elsewhere
0.000 0.491 0.509
H68.1 Obstruction of Eustachian tube
0.000 0.491 0.509
H68.0 Eustachian salpingitis
0.000 0.491 0.509
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.491 0.509
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere
0.000 0.491 0.509
K58.9 Irritable bowel syndrome without diarrhoea
0.000 0.491 0.509
H32.8 Other chorioretinal disorders in diseases classified elsewhere
0.000 0.491 0.509
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
0.000 0.491 0.509
K76.1 Chronic passive congestion of liver
0.000 0.491 0.509
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.492 0.508
K71.9 Toxic liver disease, unspecified
0.000 0.492 0.508
K71.8 Toxic liver disease with other disorders of liver
0.000 0.492 0.508
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.492 0.508
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.492 0.508
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.492 0.508

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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