TreeWAS – Variant ID: rs9345396

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	0.275	0.725
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.272	0.728
M20-M25 Other joint disorders	0.270	0.730
M20 Acquired deformities of fingers and toes	0.270	0.730
Chapter XII Diseases of the skin and subcutaneous tissue	0.270	0.730
Chapter IV Endocrine, nutritional and metabolic diseases	0.269	0.731
M20.1 Hallux valgus (acquired)	0.262	0.738
L00-L08 Infections of the skin and subcutaneous tissue	0.259	0.741
E70-E90 Metabolic disorders	0.258	0.742
Chapter XX External causes of morbidity and mortality	0.258	0.742
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.254	0.746
Chapter I Certain infectious and parasitic diseases	0.254	0.746
L03 Cellulitis	0.247	0.753
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.247	0.753
M70-M79 Other soft tissue disorders	0.246	0.754
E86 Volume depletion	0.239	0.761
B95-B98 Bacterial, viral and other infectious agents	0.238	0.762
M20.5 Other deformities of toe(s) (acquired)	0.233	0.767
L03.0 Cellulitis of finger and toe	0.232	0.768
Chapter X Diseases of the respiratory system	0.230	0.770
Chapter VIII Diseases of the ear and mastoid process	0.229	0.771
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.229	0.771
E50-E64 Other nutritional deficiencies	0.226	0.774
E87 Other disorders of fluid, electrolyte and acid-base balance	0.224	0.776
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.223	0.777
M20.4 Other hammer toe(s) (acquired)	0.221	0.779
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.220	0.780
D70-D77 Other diseases of blood and blood-forming organs	0.220	0.780
J90-J94 Other diseases of pleura	0.219	0.781
L20-L30 Dermatitis and eczema	0.219	0.781
M80-M85 Disorders of bone density and structure	0.218	0.782
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.214	0.786
J90 Pleural effusion, not elsewhere classified	0.213	0.787
D60-D64 Aplastic and other anaemias	0.213	0.787
M35 Other systemic involvement of connective tissue	0.213	0.787
L02 Cutaneous abscess, furuncle and carbuncle	0.212	0.788
L80-L99 Other disorders of the skin and subcutaneous tissue	0.212	0.788
M20.6 Acquired deformity of toe(s), unspecified	0.211	0.789
L60-L75 Disorders of skin appendages	0.211	0.789
E10-E14 Diabetes mellitus	0.211	0.789
E87.1 Hypo-osmolality and hyponatraemia	0.210	0.790
M79 Other soft tissue disorders, not elsewhere classified	0.209	0.791
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.209	0.791
L03.2 Cellulitis of face	0.208	0.792
E20-E35 Disorders of other endocrine glands	0.208	0.792
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.207	0.792
L05 Pilonidal cyst	0.207	0.793
W20-W49 Exposure to inanimate mechanical forces	0.205	0.795
L50-L54 Urticaria and erythema	0.205	0.795
M25 Other joint disorders, not elsewhere classified	0.204	0.796
Chapter VI Diseases of the nervous system	0.204	0.796
M75 Shoulder lesions	0.204	0.796
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.203	0.797
Chapter XXII Codes for special purposes	0.201	0.799
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.201	0.799
H80-H83 Diseases of inner ear	0.200	0.799
E83 Disorders of mineral metabolism	0.200	0.799
M40-M43 Deforming dorsopathies	0.200	0.800
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.199	0.801
E00-E07 Disorders of thyroid gland	0.198	0.801
S60-S69 Injuries to the wrist and hand	0.198	0.802
Chapter XVI Certain conditions originating in the perinatal period	0.197	0.803
M22 Disorders of patella	0.197	0.803
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.197	0.803
A30-A49 Other bacterial diseases	0.197	0.803
B35-B49 Mycoses	0.196	0.804
M91-M94 Chondropathies	0.195	0.804
M86-M90 Other osteopathies	0.195	0.804
M60-M63 Disorders of muscles	0.195	0.804
M00-M03 Infectious arthropathies	0.195	0.804
M45-M49 Spondylopathies	0.195	0.805
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.195	0.805
D80-D89 Certain disorders involving the immune mechanism	0.194	0.806
L03.3 Cellulitis of trunk	0.194	0.806
M20.3 Other deformity of hallux (acquired)	0.194	0.806
M20.0 Deformity of finger(s)	0.194	0.806
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.194	0.806
M34 Systemic sclerosis	0.194	0.806
M33 Dermatopolymyositis	0.194	0.806
M32 Systemic lupus erythematosus	0.194	0.806
M30 Polyarteritis nodosa and related conditions	0.194	0.806
M21 Other acquired deformities of limbs	0.194	0.806
M24 Other specific joint derangements	0.194	0.806
Y60-Y69 Misadventures to patients during surgical and medical care	0.194	0.806
L10-L14 Bullous disorders	0.193	0.807
E40-E46 Malnutrition	0.193	0.807
M31 Other necrotising vasculopathies	0.193	0.807
D70 Agranulocytosis	0.193	0.807
L40-L45 Papulosquamous disorders	0.191	0.809
M20.2 Hallux rigidus	0.190	0.810
S70-S79 Injuries to the hip and thigh	0.190	0.810
S20-S29 Injuries to the thorax	0.189	0.810
Y43 Primarily systemic agents	0.189	0.811
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.189	0.811
J09-J18 Influenza and pneumonia	0.188	0.812
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.188	0.812
X60-X84 Intentional self-harm	0.187	0.813
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.187	0.813
L04 Acute lymphadenitis	0.186	0.814
L01 Impetigo	0.186	0.814
L00 Staphylococcal scalded skin syndrome	0.186	0.814
M05-M14 Inflammatory polyarthropathies	0.186	0.814
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.186	0.814
E88 Other metabolic disorders	0.185	0.815
E85 Amyloidosis	0.185	0.815
E84 Cystic fibrosis	0.185	0.815
E80 Disorders of porphyrin and bilirubin metabolism	0.185	0.815
E79 Disorders of purine and pyrimidine metabolism	0.185	0.815
E77 Disorders of glycoprotein metabolism	0.185	0.815
E76 Disorders of glycosaminoglycan metabolism	0.185	0.815
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.185	0.815
E74 Other disorders of carbohydrate metabolism	0.185	0.815
E73 Lactose intolerance	0.185	0.815
E72 Other disorders of amino-acid metabolism	0.185	0.815
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.185	0.815
E70 Disorders of aromatic amino-acid metabolism	0.185	0.815
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.185	0.815
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.185	0.815
Y35-Y36 Legal intervention and operations of war	0.185	0.815
Y10-Y34 Event of undetermined intent	0.185	0.815
Y00-Y09 Assault	0.185	0.815
X85-X99 Assault	0.185	0.815
X58-X59 Accidental exposure to other and unspecified factors	0.185	0.815
X50-X57 Overexertion, travel and privation	0.185	0.815
X40-X49 Accidental poisoning by and exposure to noxious substances	0.185	0.815
X30-X39 Exposure to forces of nature	0.185	0.815
X20-X29 Contact with venomous animals and plants	0.185	0.815
X10-X19 Contact with heat and hot substances	0.185	0.815
X00-X09 Exposure to smoke, fire and flames	0.185	0.815
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.185	0.815
W75-W84 Other accidental threats to breathing	0.185	0.815
W65-W74 Accidental drowning and submersion	0.185	0.815
W50-W64 Exposure to animate mechanical forces	0.185	0.815
V98-V99 Other and unspecified transport accidents	0.185	0.815
V95-V97 Air and space transport accidents	0.185	0.815
V90-V94 Water transport accidents	0.185	0.815
V80-V89 Other land transport accidents	0.185	0.815
V70-V79 Bus occupant injured in transport accident	0.185	0.815
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.185	0.815
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.185	0.815
V40-V49 Car occupant injured in transport accident	0.185	0.815
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.185	0.815
V20-V29 Motorcycle rider injured in transport accident	0.185	0.815
V10-V19 Pedal cyclist injured in transport accident	0.185	0.815
V01-V09 Pedestrian injured in transport accident	0.185	0.815
A00-A09 Intestinal infectious diseases	0.185	0.815
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.184	0.815
D50-D53 Nutritional anaemias	0.184	0.816
Y57 Other and unspecified drugs and medicaments	0.184	0.816
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.183	0.817
Y95 Nosocomial condition	0.183	0.817
L89 Decubitus ulcer	0.183	0.817
M35.3 Polymyalgia rheumatica	0.182	0.818
D55-D59 Haemolytic anaemias	0.182	0.818
E55 Vitamin D deficiency	0.182	0.818
B99-B99 Other infectious diseases	0.182	0.818
B90-B94 Sequelae of infectious and parasitic diseases	0.182	0.818
B85-B89 Pediculosis, acariasis and other infestations	0.182	0.818
B65-B83 Helminthiases	0.182	0.818
B50-B64 Protozoal diseases	0.182	0.818
B20-B24 Human immunodeficiency virus [HIV] disease	0.182	0.818
B15-B19 Viral hepatitis	0.182	0.818
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.182	0.818
A80-A89 Viral infections of the central nervous system	0.182	0.818
A75-A79 Rickettsioses	0.182	0.818
A70-A74 Other diseases caused by chlamydiae	0.182	0.818
A65-A69 Other spirochaetal diseases	0.182	0.818
A50-A64 Infections with a predominantly sexual mode of transmission	0.182	0.818
A20-A28 Certain zoonotic bacterial diseases	0.182	0.818
A15-A19 Tuberculosis	0.182	0.818
M70 Soft tissue disorders related to use, overuse and pressure	0.182	0.818
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.182	0.818
Chapter II Neoplasms	0.182	0.818
E89.2 Postprocedural hypoparathyroidism	0.182	0.818
M72 Fibroblastic disorders	0.182	0.818
E10 Insulin-dependent diabetes mellitus	0.182	0.818
S00-S09 Injuries to the head	0.181	0.819
B97 Viral agents as the cause of diseases classified to other chapters	0.180	0.819
D64 Other anaemias	0.180	0.820
M75.0 Adhesive capsulitis of shoulder	0.180	0.820
E53 Deficiency of other B group vitamins	0.180	0.820
W00-W19 Falls	0.179	0.821
L03.8 Cellulitis of other sites	0.177	0.823
T79-T79 Certain early complications of trauma	0.177	0.823
T66-T78 Other and unspecified effects of external causes	0.177	0.823
T33-T35 Frostbite	0.177	0.823
T26-T28 Burns and corrosions confined to eye and internal organs	0.177	0.823
T20-T25 Burns and corrosions of external body surface, specified by site	0.177	0.823
T15-T19 Effects of foreign body entering through natural orifice	0.177	0.823
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.177	0.823
T00-T07 Injuries involving multiple body regions	0.177	0.823
S90-S99 Injuries to the ankle and foot	0.177	0.823
S10-S19 Injuries to the neck	0.177	0.823
Y52 Agents primarily affecting the cardiovascular system	0.177	0.823
J00-J06 Acute upper respiratory infections	0.177	0.823
M77 Other enthesopathies	0.176	0.823
M76 Enthesopathies of lower limb, excluding foot	0.176	0.823
M73 Soft tissue disorders in diseases classified elsewhere	0.176	0.823
M71 Other bursopathies	0.176	0.823
T80 Complications following infusion, transfusion and therapeutic injection	0.176	0.823
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.176	0.824
E89.0 Postprocedural hypothyroidism	0.175	0.824
S40-S49 Injuries to the shoulder and upper arm	0.175	0.825
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.175	0.825
H90-H95 Other disorders of ear	0.174	0.825
L92 Granulomatous disorders of skin and subcutaneous tissue	0.174	0.826
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.173	0.826
L72 Follicular cysts of skin and subcutaneous tissue	0.174	0.826
L90 Atrophic disorders of skin	0.173	0.827
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.173	0.827
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.173	0.827
C50-C50 Malignant neoplasm of breast	0.172	0.828
M84 Disorders of continuity of bone	0.172	0.828
L30 Other dermatitis	0.172	0.828
M75.4 Impingement syndrome of shoulder	0.170	0.830
L03.9 Cellulitis, unspecified	0.170	0.830
E04 Other non-toxic goitre	0.170	0.830
E87.2 Acidosis	0.170	0.830
L05.0 Pilonidal cyst with abscess	0.169	0.831
T81 Complications of procedures, not elsewhere classified	0.169	0.831
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.169	0.831
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.168	0.832
M79.7 Fibromyalgia	0.168	0.832
J95-J99 Other diseases of the respiratory system	0.168	0.832
H83 Other diseases of inner ear	0.168	0.832
W22 Striking against or struck by other objects	0.167	0.833
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.167	0.833
L29 Pruritus	0.167	0.833
M80 Osteoporosis with pathological fracture	0.167	0.833
E87.7 Fluid overload	0.166	0.834
Y51 Drugs primarily affecting the autonomic nervous system	0.166	0.834
E22 Hyperfunction of pituitary gland	0.166	0.834
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.166	0.834
H81 Disorders of vestibular function	0.165	0.834
J80-J84 Other respiratory diseases principally affecting the interstitium	0.165	0.834
G50-G59 Nerve, nerve root and plexus disorders	0.165	0.835
C50 Malignant neoplasm of breast	0.165	0.835
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.165	0.835
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.165	0.835
L97 Ulcer of lower limb, not elsewhere classified	0.164	0.836
M15-M19 Arthrosis	0.164	0.836
Y59 Other and unspecified vaccines and biological substances	0.164	0.836
Y58 Bacterial vaccines	0.164	0.836
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.164	0.836
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.164	0.836
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.164	0.836
Y53 Agents primarily affecting the gastro-intestinal system	0.164	0.836
Y50 Central nervous system stimulants, not elsewhere classified	0.164	0.836
Y49 Psychotropic drugs, not elsewhere classified	0.164	0.836
Y48 Anaesthetics and therapeutic gases	0.164	0.836
Y47 Sedatives, hypnotics and antianxiety drugs	0.164	0.836
Y46 Antiepileptics and anti-Parkinsonism drugs	0.164	0.836
Y44 Agents primarily affecting blood constituents	0.164	0.836
Y41 Other systemic anti-infectives and antiparasitics	0.164	0.836
Y40 Systemic antibiotics	0.164	0.836
M25.9 Joint disorder, unspecified	0.164	0.836
D73 Diseases of spleen	0.164	0.836
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.163	0.836
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.163	0.837
M65-M68 Disorders of synovium and tendon	0.163	0.837
E64 Sequelae of malnutrition and other nutritional deficiencies	0.162	0.838
E63 Other nutritional deficiencies	0.162	0.838
E61 Deficiency of other nutrient elements	0.162	0.838
E56 Other vitamin deficiencies	0.162	0.838
E51 Thiamine deficiency	0.162	0.838
E50 Vitamin A deficiency	0.162	0.838
E60 Dietary zinc deficiency	0.162	0.838
E59 Dietary selenium deficiency	0.162	0.838
E58 Dietary calcium deficiency	0.162	0.838
E54 Ascorbic acid deficiency	0.162	0.838
E52 Niacin deficiency [pellagra]	0.162	0.838
L03.1 Cellulitis of other parts of limb	0.162	0.838
H60-H62 Diseases of external ear	0.161	0.838
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.161	0.839
T92 Sequelae of injuries of upper limb	0.161	0.839
L27 Dermatitis due to substances taken internally	0.161	0.839
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.161	0.839
E87.4 Mixed disorder of acid-base balance	0.161	0.839
E87.3 Alkalosis	0.161	0.839
E87.0 Hyperosmolality and hypernatraemia	0.161	0.839
M79.0 Rheumatism, unspecified	0.161	0.839
Y43.3 Other antineoplastic drugs	0.161	0.839
M25.7 Osteophyte	0.160	0.840
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.160	0.840
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.160	0.840
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.160	0.840
M79.6 Pain in limb	0.160	0.840
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.160	0.840
J60-J70 Lung diseases due to external agents	0.160	0.840
Q38-Q45 Other congenital malformations of the digestive system	0.159	0.841
S80-S89 Injuries to the knee and lower leg	0.159	0.841
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.159	0.841
G20-G26 Extrapyramidal and movement disorders	0.159	0.841
L53 Other erythematous conditions	0.159	0.841
E83.5 Disorders of calcium metabolism	0.159	0.841
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.158	0.842
E89.8 Other postprocedural endocrine and metabolic disorders	0.158	0.842
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.158	0.842
E89.5 Postprocedural testicular hypofunction	0.158	0.842
E89.4 Postprocedural ovarian failure	0.158	0.842
E89.3 Postprocedural hypopituitarism	0.158	0.842
E89.1 Postprocedural hypoinsulinaemia	0.158	0.842
T31 Burns classified according to extent of body surface involved	0.158	0.842
L08 Other local infections of skin and subcutaneous tissue	0.158	0.842
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.158	0.842
D75 Other diseases of blood and blood-forming organs	0.158	0.842
D74 Methaemoglobinaemia	0.158	0.842
D72 Other disorders of white blood cells	0.158	0.842
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.158	0.842
D71 Functional disorders of polymorphonuclear neutrophils	0.158	0.842
J94 Other pleural conditions	0.157	0.842
J93 Pneumothorax	0.157	0.842
J91 Pleural effusion in conditions classified elsewhere	0.157	0.842
D64.9 Anaemia, unspecified	0.157	0.843
L28 Lichen simplex chronicus and prurigo	0.157	0.843
L25 Unspecified contact dermatitis	0.157	0.843
L24 Irritant contact dermatitis	0.157	0.843
L23 Allergic contact dermatitis	0.157	0.843
L21 Seborrhoeic dermatitis	0.157	0.843
L20 Atopic dermatitis	0.157	0.843
L26 Exfoliative dermatitis	0.157	0.843
L22 Diaper [napkin] dermatitis	0.157	0.843
M81 Osteoporosis without pathological fracture	0.157	0.843
M85 Other disorders of bone density and structure	0.157	0.843
M83 Adult osteomalacia	0.157	0.843
M82 Osteoporosis in diseases classified elsewhere	0.157	0.843
B25-B34 Other viral diseases	0.156	0.843
S60 Superficial injury of wrist and hand	0.156	0.844
E16 Other disorders of pancreatic internal secretion	0.156	0.844
C50.9 Breast, unspecified	0.156	0.844
T36-T50 Poisoning by drugs, medicaments and biological substances	0.156	0.844
S61 Open wound of wrist and hand	0.156	0.844
D62 Acute posthaemorrhagic anaemia	0.156	0.844
D63 Anaemia in chronic diseases classified elsewhere	0.156	0.844
M50-M54 Other dorsopathies	0.155	0.845
B37 Candidiasis	0.155	0.845
A41 Other septicaemia	0.155	0.845
M79.8 Other specified soft tissue disorders	0.154	0.846
Y91 Evidence of alcohol involvement determined by level of intoxication	0.154	0.846
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.154	0.846
Y98 Lifestyle-related condition	0.154	0.846
Y97 Environmental-pollution-related condition	0.154	0.846
Y96 Work-related condition	0.154	0.846
T85 Complications of other internal prosthetic devices, implants and grafts	0.154	0.846
J13 Pneumonia due to Streptococcus pneumoniae	0.154	0.846
M10 Gout	0.153	0.847
E14 Unspecified diabetes mellitus	0.153	0.847
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.153	0.847
L89.1 Stage II decubitus ulcer	0.153	0.847
M35.9 Systemic involvement of connective tissue, unspecified	0.153	0.847
M35.8 Other specified systemic involvement of connective tissue	0.153	0.847
M35.7 Hypermobility syndrome	0.153	0.847
M35.6 Relapsing panniculitis [Weber-Christian]	0.153	0.847
M35.5 Multifocal fibrosclerosis	0.153	0.847
M35.4 Diffuse (eosinophilic) fasciitis	0.153	0.847
M35.2 Behcet's disease	0.153	0.847
M35.1 Other overlap syndromes	0.153	0.847
D61 Other aplastic anaemias	0.153	0.847
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.153	0.847
S50-S59 Injuries to the elbow and forearm	0.153	0.847
E83.1 Disorders of iron metabolism	0.153	0.847
L85 Other epidermal thickening	0.152	0.847
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.152	0.848
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.152	0.848
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.152	0.848
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.152	0.848
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.152	0.848
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.152	0.848
L95 Vasculitis limited to skin, not elsewhere classified	0.152	0.848
L94 Other localised connective tissue disorders	0.152	0.848
L93 Lupus erythematosus	0.152	0.848
L87 Transepidermal elimination disorders	0.152	0.848
L88 Pyoderma gangrenosum	0.152	0.848
L86 Keratoderma in diseases classified elsewhere	0.152	0.848
L84 Corns and callosities	0.152	0.848
L83 Acanthosis nigricans	0.152	0.848
L80 Vitiligo	0.152	0.848
Y57.9 Drug or medicament, unspecified	0.152	0.848
J92 Pleural plaque	0.152	0.848
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.152	0.848
L75 Apocrine sweat disorders	0.151	0.849
L74 Eccrine sweat disorders	0.151	0.849
L73 Other follicular disorders	0.151	0.849
L71 Rosacea	0.151	0.849
L70 Acne	0.151	0.849
L68 Hypertrichosis	0.151	0.849
L67 Hair colour and hair shaft abnormalities	0.151	0.849
L66 Cicatricial alopecia [scarring hair loss]	0.151	0.849
L65 Other nonscarring hair loss	0.151	0.849
L64 Androgenic alopecia	0.151	0.849
L63 Alopecia areata	0.151	0.849
L62 Nail disorders in diseases classified elsewhere	0.151	0.849
L72.0 Epidermal cyst	0.151	0.849
E13 Other specified diabetes mellitus	0.151	0.849
E12 Malnutrition-related diabetes mellitus	0.151	0.849
E55.9 Vitamin D deficiency, unspecified	0.151	0.849
M79.9 Soft tissue disorder, unspecified	0.150	0.850
M79.5 Residual foreign body in soft tissue	0.150	0.850
M79.4 Hypertrophy of (infrapatellar) fat pad	0.150	0.850
M79.3 Panniculitis, unspecified	0.150	0.850
M79.2 Neuralgia and neuritis, unspecified	0.150	0.850
M79.1 Myalgia	0.150	0.850
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.150	0.850
T88 Other complications of surgical and medical care, not elsewhere classified	0.150	0.850
T87 Complications peculiar to reattachment and amputation	0.150	0.850
T86 Failure and rejection of transplanted organs and tissues	0.150	0.850
T83.0 Mechanical complication of urinary (indwelling) catheter	0.150	0.850
S72 Fracture of femur	0.150	0.850
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.149	0.850
E35 Disorders of endocrine glands in diseases classified elsewhere	0.149	0.851
E34 Other endocrine disorders	0.149	0.851
E32 Diseases of thymus	0.149	0.851
E31 Polyglandular dysfunction	0.149	0.851
E30 Disorders of puberty, not elsewhere classified	0.149	0.851
E29 Testicular dysfunction	0.149	0.851
E28 Ovarian dysfunction	0.149	0.851
E27 Other disorders of adrenal gland	0.149	0.851
E26 Hyperaldosteronism	0.149	0.851
E25 Adrenogenital disorders	0.149	0.851
E24 Cushing's syndrome	0.149	0.851
E23 Hypofunction and other disorders of pituitary gland	0.149	0.851
E20 Hypoparathyroidism	0.149	0.851
E10.9 Without complications	0.149	0.851
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.149	0.851
Q80-Q89 Other congenital malformations	0.149	0.851
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.149	0.851
Q60-Q64 Congenital malformations of the urinary system	0.149	0.851
Q50-Q56 Congenital malformations of genital organs	0.149	0.851
Q35-Q37 Cleft lip and cleft palate	0.149	0.851
Q30-Q34 Congenital malformations of the respiratory system	0.149	0.851
Q20-Q28 Congenital malformations of the circulatory system	0.149	0.851
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.149	0.851
Q00-Q07 Congenital malformations of the nervous system	0.149	0.851
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.149	0.851
E87.6 Hypokalaemia	0.149	0.851
M23 Internal derangement of knee	0.149	0.851
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.148	0.851
L05.9 Pilonidal cyst without abscess	0.148	0.851
M43 Other deforming dorsopathies	0.148	0.852
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.148	0.852
E05 Thyrotoxicosis [hyperthyroidism]	0.148	0.852
E53.8 Deficiency of other specified B group vitamins	0.148	0.852
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.147	0.852
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.147	0.852
W49 Exposure to other and unspecified inanimate mechanical forces	0.147	0.853
W46 Contact with hypodermic needle	0.147	0.853
W45 Foreign body or object entering through skin	0.147	0.853
W44 Foreign body entering into or through eye or natural orifice	0.147	0.853
W43 Exposure to vibration	0.147	0.853
W42 Exposure to noise	0.147	0.853
W41 Exposure to high-pressure jet	0.147	0.853
W40 Explosion of other materials	0.147	0.853
W39 Discharge of firework	0.147	0.853
W38 Explosion and rupture of other specified pressurised devices	0.147	0.853
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.147	0.853
W36 Explosion and rupture of gas cylinder	0.147	0.853
W35 Explosion and rupture of boiler	0.147	0.853
W34 Discharge from other and unspecified firearms	0.147	0.853
W33 Rifle, shotgun and larger firearm discharge	0.147	0.853
W32 Handgun discharge	0.147	0.853
W31 Contact with other and unspecified machinery	0.147	0.853
W30 Contact with agricultural machinery	0.147	0.853
W29 Contact with other powered hand tools and household machinery	0.147	0.853
W28 Contact with powered lawn mower	0.147	0.853
W27 Contact with nonpowered hand tool	0.147	0.853
W26 Contact with knife, sword or dagger	0.147	0.853
W25 Contact with sharp glass	0.147	0.853
W24 Contact with lifting and transmission devices, not elsewhere classified	0.147	0.853
W23 Caught, crushed, jammed or pinched in or between objects	0.147	0.853
W21 Striking against or struck by sports equipment	0.147	0.853
W20 Struck by thrown, projected or falling object	0.147	0.853
L54 Erythema in diseases classified elsewhere	0.147	0.853
L51 Erythema multiforme	0.147	0.853
L50 Urticaria	0.147	0.853
L52 Erythema nodosum	0.147	0.853
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.147	0.853
L81 Other disorders of pigmentation	0.147	0.853
L89.9 Decubitus ulcer and pressure area, unspecified	0.147	0.853
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.147	0.853
M25.8 Other specified joint disorders	0.146	0.853
M25.6 Stiffness of joint, not elsewhere classified	0.146	0.853
M25.3 Other instability of joint	0.146	0.853
M25.2 Flail joint	0.146	0.853
M25.1 Fistula of joint	0.146	0.853
M25.0 Haemarthrosis	0.146	0.853
G70-G73 Diseases of myoneural junction and muscle	0.146	0.854
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.146	0.854
G00-G09 Inflammatory diseases of the central nervous system	0.146	0.854
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.146	0.854
M75.8 Other shoulder lesions	0.146	0.854
M75.9 Shoulder lesion, unspecified	0.146	0.854
M75.3 Calcific tendinitis of shoulder	0.146	0.854
M75.2 Bicipital tendinitis	0.146	0.854
G80-G83 Cerebral palsy and other paralytic syndromes	0.146	0.854
M45 Ankylosing spondylitis	0.146	0.854
E15 Nondiabetic hypoglycaemic coma	0.146	0.854
M47 Spondylosis	0.146	0.854
C50.1 Central portion of breast	0.146	0.854
S62 Fracture at wrist and hand level	0.145	0.855
G30-G32 Other degenerative diseases of the nervous system	0.145	0.855

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations