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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9348793
log Bayes Factor = 84.3643
Chromosome 6   position 28,084,189  (GRCh37) Explore rs9348793 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.998 0.002 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.003 0.997
E00-E07 Disorders of thyroid gland
0.997 0.003 0.000
E16 Other disorders of pancreatic internal secretion
0.996 0.004 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.996 0.004 0.000
E16.2 Hypoglycaemia, unspecified
0.995 0.005 0.000
E05.9 Thyrotoxicosis, unspecified
0.995 0.005 0.000
N40 Hyperplasia of prostate
0.000 0.009 0.991
E14 Unspecified diabetes mellitus
0.990 0.010 0.000
E10.3 With ophthalmic complications
0.985 0.015 0.000
K40 Inguinal hernia
0.000 0.019 0.981
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.022 0.978
E10.1 With ketoacidosis
0.952 0.048 0.000
E11 Non-insulin-dependent diabetes mellitus
0.931 0.069 0.000
E20-E35 Disorders of other endocrine glands
0.931 0.069 0.000
E11.5 With peripheral circulatory complications
0.922 0.078 0.000
E14.3 With ophthalmic complications
0.914 0.086 0.000
E10.2 With renal complications
0.910 0.090 0.000
E14.9 Without complications
0.910 0.090 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.905 0.095 0.000
E27 Other disorders of adrenal gland
0.898 0.102 0.000
E27.1 Primary adrenocortical insufficiency
0.883 0.117 0.000
E03 Other hypothyroidism
0.882 0.118 0.000
E23 Hypofunction and other disorders of pituitary gland
0.881 0.119 0.000
E10.6 With other specified complications
0.872 0.128 0.000
E11.3 With ophthalmic complications
0.842 0.158 0.000
N40-N51 Diseases of male genital organs
0.000 0.162 0.838
E16.0 Drug-induced hypoglycaemia without coma
0.827 0.173 0.000
E23.2 Diabetes insipidus
0.827 0.173 0.000
N42 Other disorders of prostate
0.000 0.176 0.824
E14.4 With neurological complications
0.818 0.182 0.000
E03.9 Hypothyroidism, unspecified
0.815 0.185 0.000
E10.5 With peripheral circulatory complications
0.813 0.187 0.000
N42.8 Other specified disorders of prostate
0.000 0.201 0.799
N41 Inflammatory diseases of prostate
0.000 0.205 0.795
K90 Intestinal malabsorption
0.790 0.210 0.000
E10.7 With multiple complications
0.781 0.219 0.000
E07 Other disorders of thyroid
0.776 0.224 0.000
E10.0 With coma
0.774 0.226 0.000
E14.6 With other specified complications
0.772 0.227 0.000
E14.1 With ketoacidosis
0.772 0.228 0.000
E11.6 With other specified complications
0.770 0.230 0.000
E10.4 With neurological complications
0.767 0.233 0.000
E14.2 Withrenal complications
0.762 0.238 0.000
E20 Hypoparathyroidism
0.761 0.239 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.264 0.736
N41.0 Acute prostatitis
0.000 0.264 0.736
E14.5 With peripheral circulatory complications
0.732 0.268 0.000
E31 Polyglandular dysfunction
0.727 0.273 0.000
E23.0 Hypopituitarism
0.721 0.279 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.280 0.720
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.715 0.285 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.715 0.285 0.000
E00 Congenital iodine-deficiency syndrome
0.715 0.285 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.714 0.286 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.714 0.286 0.000
E16.4 Abnormal secretion of gastrin
0.714 0.286 0.000
E16.3 Increased secretion of glucagon
0.714 0.286 0.000
E05.5 Thyroid crisis or storm
0.714 0.286 0.000
E05.4 Thyrotoxicosis factitia
0.714 0.286 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.714 0.286 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.714 0.286 0.000
E24 Cushing's syndrome
0.710 0.290 0.000
E14.7 With multiple complications
0.710 0.290 0.000
E14.0 With coma
0.710 0.290 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.707 0.293 0.000
E27.2 Addisonian crisis
0.705 0.295 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.297 0.703
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.297 0.703
E16.1 Other hypoglycaemia
0.702 0.297 0.000
N46 Male infertility
0.000 0.299 0.701
E27.4 Other and unspecified adrenocortical insufficiency
0.698 0.302 0.000
E11.0 With coma
0.684 0.316 0.000
E25 Adrenogenital disorders
0.673 0.327 0.000
E40-E46 Malnutrition
0.670 0.329 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.331 0.669
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.000 0.331 0.669
E11.7 With multiple complications
0.668 0.332 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.667 0.332 0.000
E32 Diseases of thymus
0.667 0.332 0.000
E30 Disorders of puberty, not elsewhere classified
0.667 0.332 0.000
N44 Torsion of testis
0.000 0.335 0.665
N42.0 Calculus of prostate
0.000 0.336 0.664
E27.3 Drug-induced adrenocortical insufficiency
0.663 0.337 0.000
N45 Orchitis and epididymitis
0.000 0.344 0.656
K90.9 Intestinal malabsorption, unspecified
0.653 0.347 0.000
E23.6 Other disorders of pituitary gland
0.647 0.352 0.000
E14.8 With unspecified complications
0.645 0.355 0.000
E27.5 Adrenomedullary hyperfunction
0.644 0.356 0.000
E27.0 Other adrenocortical overactivity
0.644 0.356 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.642 0.358 0.000
E20.9 Hypoparathyroidism, unspecified
0.640 0.360 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.636 0.364 0.000
N42.2 Atrophy of prostate
0.000 0.367 0.633
E03.5 Myxoedema coma
0.632 0.368 0.000
E03.4 Atrophy of thyroid (acquired)
0.632 0.368 0.000
E03.3 Postinfectious hypothyroidism
0.632 0.368 0.000
E03.1 Congenital hypothyroidism without goitre
0.632 0.368 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.632 0.368 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.632 0.368 0.000
E23.1 Drug-induced hypopituitarism
0.632 0.368 0.000
E05.8 Other thyrotoxicosis
0.631 0.368 0.000
E27.9 Disorder of adrenal gland, unspecified
0.629 0.371 0.000
E07.8 Other specified disorders of thyroid
0.618 0.382 0.000
E10.8 With unspecified complications
0.617 0.383 0.000
E50-E64 Other nutritional deficiencies
0.611 0.389 0.000
E23.7 Disorder of pituitary gland, unspecified
0.608 0.391 0.000
E28 Ovarian dysfunction
0.604 0.396 0.000
K90.8 Other intestinal malabsorption
0.592 0.408 0.000
N42.3 Dysplasia of prostate
0.000 0.409 0.591
E11.1 With ketoacidosis
0.589 0.411 0.000
E06 Thyroiditis
0.588 0.412 0.000
E31.0 Autoimmune polyglandular failure
0.580 0.420 0.000
E24.2 Drug-induced Cushing's syndrome
0.580 0.420 0.000
E26 Hyperaldosteronism
0.572 0.428 0.000
N41.3 Prostatocystitis
0.000 0.430 0.570
N41.2 Abscess of prostate
0.000 0.430 0.570
K90.3 Pancreatic steatorrhoea
0.567 0.433 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.567 0.433 0.000
K90.1 Tropical sprue
0.567 0.433 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.435 0.565
E03.8 Other specified hypothyroidism
0.560 0.440 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.441 0.559
E07.1 Dyshormogenetic goitre
0.556 0.444 0.000
E07.0 Hypersecretion of calcitonin
0.556 0.444 0.000
E07.9 Disorder of thyroid, unspecified
0.556 0.444 0.000
E29 Testicular dysfunction
0.556 0.444 0.000
E24.0 Pituitary-dependent Cushing's disease
0.552 0.448 0.000
E13 Other specified diabetes mellitus
0.549 0.450 0.000
E20.8 Other hypoparathyroidism
0.546 0.454 0.000
E20.1 Pseudohypoparathyroidism
0.546 0.454 0.000
E20.0 Idiopathic hypoparathyroidism
0.546 0.454 0.000
N41.8 Other inflammatory diseases of prostate
0.000 0.459 0.541
E31.9 Polyglandular dysfunction, unspecified
0.521 0.479 0.000
E31.8 Other polyglandular dysfunction
0.521 0.479 0.000
E31.1 Polyglandular hyperfunction
0.521 0.479 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E11.8 With unspecified complications
0.513 0.486 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.512 0.487 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.512 0.487 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.512 0.487 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.512 0.487 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.512 0.487 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.512 0.487 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.512 0.487 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.512 0.487 0.000
E24.8 Other Cushing's syndrome
0.509 0.491 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.509 0.491 0.000
E24.3 Ectopic ACTH syndrome
0.509 0.491 0.000
E24.1 Nelson's syndrome
0.509 0.491 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.490 0.509 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.488 0.512 0.000
E25.9 Adrenogenital disorder, unspecified
0.482 0.517 0.000
E25.8 Other adrenogenital disorders
0.482 0.517 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.481 0.519 0.000
E45 Retarded development following protein-energy malnutrition
0.481 0.519 0.000
E43 Unspecified severe protein-energy malnutrition
0.481 0.519 0.000
E42 Marasmic kwashiorkor
0.481 0.519 0.000
E41 Nutritional marasmus
0.481 0.519 0.000
E40 Kwashiorkor
0.481 0.519 0.000
E30.9 Disorder of puberty, unspecified
0.479 0.521 0.000
E30.8 Other disorders of puberty
0.479 0.521 0.000
E30.1 Precocious puberty
0.479 0.521 0.000
E30.0 Delayed puberty
0.479 0.521 0.000
E32.9 Disease of thymus, unspecified
0.479 0.521 0.000
E32.8 Other diseases of thymus
0.479 0.521 0.000
E32.1 Abscess of thymus
0.479 0.521 0.000
E32.0 Persistent hyperplasia of thymus
0.479 0.521 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.479 0.521 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.479 0.521 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.479 0.521 0.000
E28.3 Primary ovarian failure
0.467 0.533 0.000
E61 Deficiency of other nutrient elements
0.466 0.534 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.540 0.460
E34 Other endocrine disorders
0.444 0.555 0.000
E53 Deficiency of other B group vitamins
0.439 0.561 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.438 0.561 0.000
E63 Other nutritional deficiencies
0.438 0.561 0.000
E56 Other vitamin deficiencies
0.438 0.561 0.000
E50 Vitamin A deficiency
0.438 0.561 0.000
E60 Dietary zinc deficiency
0.438 0.561 0.000
E59 Dietary selenium deficiency
0.438 0.561 0.000
E54 Ascorbic acid deficiency
0.438 0.561 0.000
E52 Niacin deficiency [pellagra]
0.438 0.561 0.000
E51 Thiamine deficiency
0.436 0.564 0.000
E46 Unspecified protein-energy malnutrition
0.434 0.565 0.000
E28.9 Ovarian dysfunction, unspecified
0.433 0.567 0.000
E28.8 Other ovarian dysfunction
0.433 0.567 0.000
E28.1 Androgen excess
0.433 0.567 0.000
E28.0 Oestrogen excess
0.433 0.567 0.000
N42.9 Disorder of prostate, unspecified
0.000 0.567 0.433
E06.9 Thyroiditis, unspecified
0.429 0.570 0.000
E06.5 Other chronic thyroiditis
0.427 0.573 0.000
E58 Dietary calcium deficiency
0.426 0.574 0.000
E06.4 Drug-induced thyroiditis
0.422 0.578 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.422 0.578 0.000
E06.1 Subacute thyroiditis
0.422 0.578 0.000
E06.0 Acute thyroiditis
0.422 0.578 0.000
E26.9 Hyperaldosteronism, unspecified
0.410 0.590 0.000
E26.8 Other hyperaldosteronism
0.410 0.590 0.000
E26.1 Secondary hyperaldosteronism
0.410 0.590 0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.000 0.595 0.405
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.000 0.595 0.405
N51.0 Disorders of prostate in diseases classified elsewhere
0.000 0.595 0.405
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.000 0.596 0.403
E29.9 Testicular dysfunction, unspecified
0.398 0.601 0.000
E29.8 Other testicular dysfunction
0.398 0.601 0.000
E29.0 Testicular hyperfunction
0.398 0.601 0.000
E24.9 Cushing's syndrome, unspecified
0.397 0.603 0.000
E13.8 With unspecified complications
0.394 0.606 0.000
E13.7 With multiple complications
0.394 0.606 0.000
E13.6 With other specified complications
0.394 0.606 0.000
E13.5 With peripheral circulatory complications
0.394 0.606 0.000
E13.4 With neurological complications
0.394 0.606 0.000
E13.2 With renal complications
0.394 0.606 0.000
E13.1 With ketoacidosis
0.394 0.606 0.000
E13.0 With coma
0.394 0.606 0.000
E13.3 With ophthalmic complications
0.394 0.606 0.000
E61.1 Iron deficiency
0.389 0.611 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.388 0.612 0.000
N43 Hydrocele and spermatocele
0.000 0.612 0.388
N41.1 Chronic prostatitis
0.000 0.614 0.386
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.615 0.385
E11.2 With renal complications
0.381 0.619 0.000
E22 Hyperfunction of pituitary gland
0.375 0.624 0.000
N51.2 Balanitis in diseases classified elsewhere
0.000 0.631 0.369
N50 Other disorders of male genital organs
0.000 0.648 0.352
E44.1 Mild protein-energy malnutrition
0.345 0.655 0.000
E44.0 Moderate protein-energy malnutrition
0.345 0.655 0.000
E53.8 Deficiency of other specified B group vitamins
0.336 0.664 0.000
E61.9 Deficiency of nutrient element, unspecified
0.334 0.665 0.000
E61.8 Deficiency of other specified nutrient elements
0.334 0.665 0.000
E61.7 Deficiency of multiple nutrient elements
0.334 0.665 0.000
E61.6 Vanadium deficiency
0.334 0.665 0.000
E61.5 Molybdenum deficiency
0.334 0.665 0.000
E61.4 Chromium deficiency
0.334 0.665 0.000
E61.3 Manganese deficiency
0.334 0.665 0.000
E61.0 Copper deficiency
0.334 0.665 0.000
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.670 0.330
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.670 0.330
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.670 0.330
E34.5 Androgen resistance syndrome
0.319 0.681 0.000
E34.4 Constitutional tall stature
0.319 0.681 0.000
E34.3 Short stature, not elsewhere classified
0.319 0.681 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.319 0.681 0.000
E34.1 Other hypersecretion of intestinal hormones
0.319 0.681 0.000
E53.1 Pyridoxine deficiency
0.315 0.685 0.000
E53.0 Riboflavin deficiency
0.315 0.685 0.000
E26.0 Primary hyperaldosteronism
0.315 0.685 0.000
E50.9 Vitamin A deficiency, unspecified
0.314 0.685 0.000
E50.8 Other manifestations of vitamin A deficiency
0.314 0.685 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.314 0.685 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.314 0.685 0.000
E50.5 Vitamin A deficiency with night blindness
0.314 0.685 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.314 0.685 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.314 0.685 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.314 0.685 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.314 0.685 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.314 0.685 0.000
E56.9 Vitamin deficiency, unspecified
0.314 0.685 0.000
E56.8 Deficiency of other vitamins
0.314 0.685 0.000
E56.1 Deficiency of vitamin K
0.314 0.685 0.000
E56.0 Deficiency of vitamin E
0.314 0.685 0.000
E63.9 Nutritional deficiency, unspecified
0.314 0.685 0.000
E63.8 Other specified nutritional deficiencies
0.314 0.685 0.000
E63.1 Imbalance of constituents of food intake
0.314 0.685 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.314 0.685 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.314 0.685 0.000
E64.8 Sequelae of other nutritional deficiencies
0.314 0.685 0.000
E64.3 Sequelae of rickets
0.314 0.685 0.000
E64.2 Sequelae of vitamin C deficiency
0.314 0.685 0.000
E64.1 Sequelae of vitamin A deficiency
0.314 0.685 0.000
E64.0 Sequelae of protein-energy malnutrition
0.314 0.685 0.000
E51.9 Thiamine deficiency, unspecified
0.313 0.687 0.000
E51.8 Other manifestations of thiamine deficiency
0.313 0.687 0.000
E51.1 Beriberi
0.313 0.687 0.000
E28.2 Polycystic ovarian syndrome
0.312 0.688 0.000
E51.2 Wernicke's encephalopathy
0.310 0.690 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.694 0.306
E11.9 Without complications
0.305 0.695 0.000
E55 Vitamin D deficiency
0.304 0.696 0.000
N50.0 Atrophy of testis
0.000 0.701 0.299
E21.4 Other specified disorders of parathyroid gland
0.299 0.701 0.000
E34.8 Other specified endocrine disorders
0.294 0.705 0.000
N49.8 Inflammatory disorders of other specified male genital organs
0.000 0.707 0.293
E53.9 Vitamin B deficiency, unspecified
0.291 0.709 0.000
N50.9 Disorder of male genital organs, unspecified
0.000 0.710 0.290
E61.2 Magnesium deficiency
0.289 0.711 0.000
E21.2 Other hyperparathyroidism
0.288 0.712 0.000
E29.1 Testicular hypofunction
0.286 0.713 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.279 0.721 0.000
N43.2 Other hydrocele
0.000 0.721 0.278
N43.1 Infected hydrocele
0.000 0.721 0.278
N43.0 Encysted hydrocele
0.000 0.721 0.278
E11.4 With neurological complications
0.277 0.723 0.000
E34.0 Carcinoid syndrome
0.273 0.726 0.000
E65-E68 Obesity and other hyperalimentation
0.272 0.728 0.000
E06.3 Autoimmune thyroiditis
0.270 0.730 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.269 0.730 0.000
E22.8 Other hyperfunction of pituitary gland
0.269 0.730 0.000
N49.2 Inflammatory disorders of scrotum
0.000 0.751 0.249
K40-K46 Hernia
0.000 0.751 0.249
N48 Other disorders of penis
0.000 0.759 0.241
E27.8 Other specified disorders of adrenal gland
0.236 0.761 0.003
N43.4 Spermatocele
0.000 0.761 0.238
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.238 0.762 0.000
K41 Femoral hernia
0.000 0.766 0.234
E22.1 Hyperprolactinaemia
0.233 0.767 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.233 0.767 0.000
E34.9 Endocrine disorder, unspecified
0.229 0.771 0.001
E13.9 Without complications
0.227 0.773 0.001
N48.4 Impotence of organic origin
0.000 0.780 0.220
E55.0 Rickets, active
0.218 0.782 0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.000 0.789 0.211
E21.3 Hyperparathyroidism, unspecified
0.210 0.790 0.000
N48.1 Balanoposthitis
0.000 0.791 0.208
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.000 0.796 0.204
E67 Other hyperalimentation
0.195 0.805 0.000
E68 Sequelae of hyperalimentation
0.195 0.805 0.000
E04 Other non-toxic goitre
0.194 0.806 0.000
K46 Unspecified abdominal hernia
0.000 0.816 0.184
N48.2 Other inflammatory disorders of penis
0.000 0.829 0.171
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.000 0.832 0.168
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.000 0.832 0.168
K41.1 Bilateral femoral hernia, with gangrene
0.000 0.832 0.168
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.000 0.832 0.168
E21.0 Primary hyperparathyroidism
0.162 0.838 0.000
N48.5 Ulcer of penis
0.000 0.841 0.158
N43.3 Hydrocele, unspecified
0.000 0.849 0.151
N48.3 Priapism
0.000 0.852 0.148
K43 Ventral hernia
0.000 0.852 0.147
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.000 0.853 0.147
E22.0 Acromegaly and pituitary gigantism
0.146 0.853 0.001
N48.0 Leukoplakia of penis
0.000 0.856 0.144
E67.8 Other specified hyperalimentation
0.140 0.860 0.000
E67.3 Hypervitaminosis D
0.140 0.860 0.000
E67.2 Megavitamin-B6 syndrome
0.140 0.860 0.000
E67.1 Hypercarotenaemia
0.140 0.860 0.000
E67.0 Hypervitaminosis A
0.140 0.860 0.000
E04.8 Other specified non-toxic goitre
0.139 0.860 0.000
K46.1 Unspecified abdominal hernia with gangrene
0.000 0.868 0.132
K75.4 Autoimmune hepatitis
0.130 0.870 0.000
K44 Diaphragmatic hernia
0.000 0.873 0.127
K75 Other inflammatory liver diseases
0.119 0.881 0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.000 0.883 0.117
E04.0 Non-toxic diffuse goitre
0.115 0.885 0.000
E04.9 Non-toxic goitre, unspecified
0.115 0.885 0.000
K75.8 Other specified inflammatory liver diseases
0.115 0.885 0.000
K45 Other abdominal hernia
0.000 0.886 0.113
K75.9 Inflammatory liver disease, unspecified
0.113 0.887 0.000
E65 Localised adiposity
0.109 0.890 0.001
K43.9 Ventral hernia without obstruction or gangrene
0.000 0.890 0.110
K43.7 Other and unspecified ventral hernia with gangrene
0.000 0.894 0.106
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.000 0.894 0.106
K43.5 Parastomal hernia without obstruction or gangrene
0.000 0.894 0.106
K43.4 Parastomal hernia with gangrene
0.000 0.894 0.106
K43.3 Parastomal hernia with obstruction, without gangrene
0.000 0.894 0.106
K43.2 Incisional hernia without obstruction or gangrene
0.000 0.894 0.106
K43.1 Ventral hernia with gangrene
0.000 0.894 0.106
E04.1 Non-toxic single thyroid nodule
0.101 0.899 0.000
R47.0 Dysphasia and aphasia
0.100 0.900 0.000
K42 Umbilical hernia
0.000 0.908 0.092
K44.1 Diaphragmatic hernia with gangrene
0.000 0.909 0.091
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.910 0.090
E83 Disorders of mineral metabolism
0.006 0.910 0.084
K75.3 Granulomatous hepatitis, not elsewhere classified
0.086 0.914 0.000
K75.2 Nonspecific reactive hepatitis
0.086 0.914 0.000
K75.1 Phlebitis of portal vein
0.086 0.914 0.000
R47 Speech disturbances, not elsewhere classified
0.085 0.915 0.000
E55.9 Vitamin D deficiency, unspecified
0.083 0.916 0.000
R47.1 Dysarthria and anarthria
0.083 0.917 0.000
K45.1 Other specified abdominal hernia with gangrene
0.000 0.918 0.081
N48.6 Balanitis xerotica obliterans
0.000 0.922 0.078
N48.9 Disorder of penis, unspecified
0.001 0.930 0.069
K43.0 Ventral hernia with obstruction, without gangrene
0.000 0.933 0.067
K42.1 Umbilical hernia with gangrene
0.000 0.934 0.066
E83.9 Disorder of mineral metabolism, unspecified
0.004 0.935 0.060
E83.8 Other disorders of mineral metabolism
0.004 0.935 0.060
E83.2 Disorders of zinc metabolism
0.004 0.935 0.060
E83.0 Disorders of copper metabolism
0.004 0.935 0.060
E83.3 Disorders of phosphorus metabolism
0.003 0.937 0.061
K45.8 Other specified abdominal hernia without obstruction or gangrene
0.000 0.937 0.062
K90-K93 Other diseases of the digestive system
0.050 0.942 0.008
R47.8 Other and unspecified speech disturbances
0.055 0.945 0.000
K45.0 Other specified abdominal hernia with obstruction, without gangrene
0.001 0.947 0.052
N48.8 Other specified disorders of penis
0.000 0.950 0.050
K75.0 Abscess of liver
0.048 0.952 0.000
K42.0 Umbilical hernia with obstruction, without gangrene
0.000 0.953 0.047
N50.1 Vascular disorders of male genital organs
0.000 0.954 0.046
I83 Varicose veins of lower extremities
0.000 0.956 0.044
R30-R39 Symptoms and signs involving the urinary system
0.000 0.957 0.043
R30 Pain associated with micturition
0.000 0.958 0.042
R30.0 Dysuria
0.000 0.958 0.042
M75.0 Adhesive capsulitis of shoulder
0.042 0.958 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.036 0.958 0.006
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.959 0.041
M75.2 Bicipital tendinitis
0.039 0.961 0.000
M75 Shoulder lesions
0.037 0.963 0.000
N39.0 Urinary tract infection, site not specified
0.000 0.963 0.037
M20.1 Hallux valgus (acquired)
0.000 0.966 0.034
R30.1 Vesical tenesmus
0.000 0.966 0.034
M75.5 Bursitis of shoulder
0.032 0.968 0.000
E04.2 Non-toxic multinodular goitre
0.031 0.969 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.026 0.970 0.004
K93.1 Megacolon in Chagas' disease
0.026 0.970 0.004
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.026 0.970 0.004
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.970 0.030
M75.4 Impingement syndrome of shoulder
0.030 0.970 0.000
M75.8 Other shoulder lesions
0.029 0.971 0.000
T39.1 4-Aminophenol derivatives
0.000 0.971 0.029
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.972 0.028
R30.9 Painful micturition, unspecified
0.000 0.972 0.028
R36 Urethral discharge
0.000 0.972 0.028
Z90.5 Acquired absence of kidney
0.000 0.973 0.027
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.973 0.027
K42.9 Umbilical hernia without obstruction or gangrene
0.000 0.973 0.027
M75.1 Rotator cuff syndrome
0.027 0.973 0.000
T39.0 Salicylates
0.000 0.973 0.027
E83.4 Disorders of magnesium metabolism
0.004 0.974 0.022
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.975 0.025
E66 Obesity
0.025 0.975 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.975 0.025
R47-R49 Symptoms and signs involving speech and voice
0.025 0.975 0.000
M75.81 Other shoulder lesions, right shoulder
0.024 0.976 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.976 0.024
R34 Anuria and oliguria
0.000 0.977 0.023
L29.0 Pruritus ani
0.000 0.977 0.023
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.979 0.020
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.980 0.020
T39.4 Antirheumatics, not elsewhere classified
0.000 0.980 0.020
T39.2 Pyrazolone derivatives
0.000 0.980 0.020
R39 Other symptoms and signs involving the urinary system
0.000 0.981 0.019
E66.1 Drug-induced obesity
0.018 0.982 0.000
E70-E90 Metabolic disorders
0.016 0.982 0.002
N39 Other disorders of urinary system
0.000 0.982 0.018
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.018 0.982 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.982 0.017
T50.8 Diagnostic agents
0.000 0.983 0.017
T50.7 Analeptics and opioid receptor antagonists
0.000 0.983 0.017
T50.5 Appetite depressants
0.000 0.983 0.017
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.983 0.017
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.983 0.017
T50.1 Loop [high-ceiling] diuretics
0.000 0.983 0.017
T50.0 Mineralocorticoids and their antagonists
0.000 0.983 0.017
K70-K77 Diseases of liver
0.017 0.983 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.984 0.016
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.984 0.016
T42.4 Benzodiazepines
0.000 0.984 0.016
N39.9 Disorder of urinary system, unspecified
0.000 0.984 0.016
T50.4 Drugs affecting uric acid metabolism
0.000 0.984 0.016
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.984 0.016
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.985 0.015
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.000 0.985 0.015
K73 Chronic hepatitis, not elsewhere classified
0.015 0.985 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.985 0.015
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.985 0.015
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.985 0.015
E66.2 Extreme obesity with alveolar hypoventilation
0.015 0.985 0.000
E84 Cystic fibrosis
0.013 0.986 0.001
I82 Other venous embolism and thrombosis
0.000 0.986 0.014
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.986 0.014
K92.0 Haematemesis
0.000 0.986 0.014
K72 Hepatic failure, not elsewhere classified
0.014 0.986 0.000
N39.8 Other specified disorders of urinary system
0.000 0.986 0.014
T36 Poisoning by systemic antibiotics
0.000 0.986 0.014
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.013 0.986 0.001
R39.2 Extrarenal uraemia
0.000 0.986 0.014
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.986 0.014
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.986 0.013
M13.00 Polyarthritis, unspecified (Multiple sites)
0.013 0.987 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.000 0.987 0.013
T42.1 Iminostilbenes
0.000 0.987 0.013
R35 Polyuria
0.000 0.987 0.013
E79 Disorders of purine and pyrimidine metabolism
0.012 0.987 0.002
E77 Disorders of glycoprotein metabolism
0.012 0.987 0.002
E76 Disorders of glycosaminoglycan metabolism
0.012 0.987 0.002
E72 Other disorders of amino-acid metabolism
0.012 0.987 0.002
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.012 0.987 0.002
E70 Disorders of aromatic amino-acid metabolism
0.012 0.987 0.002
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.012 0.987 0.002
N32.0 Bladder-neck obstruction
0.000 0.987 0.013
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.987 0.013
E73 Lactose intolerance
0.012 0.987 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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