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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9357004
log Bayes Factor = 65.6233
Chromosome 6   position 26,303,319  (GRCh37) Explore rs9357004 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E83 Disorders of mineral metabolism
0.000 0.118 0.882
E16.2 Hypoglycaemia, unspecified
0.000 0.140 0.860
E16 Other disorders of pancreatic internal secretion
0.000 0.148 0.852
E70-E90 Metabolic disorders
0.000 0.153 0.847
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.157 0.843
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.163 0.837
E10-E14 Diabetes mellitus
0.000 0.176 0.824
E11 Non-insulin-dependent diabetes mellitus
0.000 0.181 0.819
E11.9 Without complications
0.000 0.198 0.802
E88 Other metabolic disorders
0.000 0.227 0.773
E11.5 With peripheral circulatory complications
0.000 0.235 0.765
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.238 0.762
E73 Lactose intolerance
0.000 0.253 0.747
E11.2 With renal complications
0.000 0.271 0.729
E83.3 Disorders of phosphorus metabolism
0.000 0.277 0.723
E11.0 With coma
0.000 0.288 0.712
E84 Cystic fibrosis
0.000 0.292 0.708
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.308 0.692
E10 Insulin-dependent diabetes mellitus
0.000 0.318 0.682
E40-E46 Malnutrition
0.000 0.324 0.676
E73.9 Lactose intolerance, unspecified
0.000 0.325 0.675
E11.1 With ketoacidosis
0.000 0.327 0.673
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.334 0.665
E16.1 Other hypoglycaemia
0.000 0.335 0.665
E80.4 Gilbert's syndrome
0.000 0.336 0.664
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.345 0.655
E70 Disorders of aromatic amino-acid metabolism
0.000 0.354 0.646
E88.8 Other specified metabolic disorders
0.000 0.355 0.645
E80.1 Porphyria cutanea tarda
0.000 0.360 0.640
E83.8 Other disorders of mineral metabolism
0.000 0.368 0.632
E83.2 Disorders of zinc metabolism
0.000 0.368 0.632
E83.0 Disorders of copper metabolism
0.000 0.368 0.632
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.372 0.628
E10.1 With ketoacidosis
0.000 0.373 0.627
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.388 0.612
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.389 0.611
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.389 0.611
E16.4 Abnormal secretion of gastrin
0.000 0.389 0.611
E16.3 Increased secretion of glucagon
0.000 0.389 0.611
E84.9 Cystic fibrosis, unspecified
0.000 0.392 0.608
E76 Disorders of glycosaminoglycan metabolism
0.000 0.393 0.607
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.393 0.607
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.393 0.607
E15 Nondiabetic hypoglycaemic coma
0.000 0.395 0.605
E10.0 With coma
0.000 0.409 0.591
E12 Malnutrition-related diabetes mellitus
0.000 0.409 0.591
E11.7 With multiple complications
0.000 0.412 0.587
E77 Disorders of glycoprotein metabolism
0.000 0.416 0.584
E72 Other disorders of amino-acid metabolism
0.000 0.422 0.578
K90 Intestinal malabsorption
0.000 0.429 0.571
E13 Other specified diabetes mellitus
0.000 0.430 0.570
E74 Other disorders of carbohydrate metabolism
0.000 0.433 0.566
E10.5 With peripheral circulatory complications
0.000 0.435 0.565
E46 Unspecified protein-energy malnutrition
0.000 0.440 0.560
E80.2 Other porphyria
0.000 0.441 0.559
E88.3 Tumour lysis syndrome
0.000 0.452 0.548
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.454 0.546
E80.5 Crigler-Najjar syndrome
0.000 0.454 0.546
E80.3 Defects of catalase and peroxydase
0.000 0.454 0.546
E80.0 Hereditary erythropoietic porphyria
0.000 0.454 0.546
E11.8 With unspecified complications
0.000 0.462 0.538
E73.8 Other lactose intolerance
0.000 0.465 0.535
E73.1 Secondary lactase deficiency
0.000 0.465 0.535
E73.0 Congenital lactase deficiency
0.000 0.465 0.535
E88.9 Metabolic disorder, unspecified
0.000 0.468 0.531
E79 Disorders of purine and pyrimidine metabolism
0.000 0.477 0.522
E10.8 With unspecified complications
0.000 0.491 0.509
E80.6 Other disorders of bilirubin metabolism
0.000 0.491 0.509
E84.8 Cystic fibrosis with other manifestations
0.000 0.492 0.508
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.492 0.508
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.492 0.508
E70.3 Albinism
0.000 0.498 0.501
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.515 0.485
E45 Retarded development following protein-energy malnutrition
0.000 0.515 0.485
E43 Unspecified severe protein-energy malnutrition
0.000 0.515 0.485
E42 Marasmic kwashiorkor
0.000 0.515 0.485
E41 Nutritional marasmus
0.000 0.515 0.485
E40 Kwashiorkor
0.000 0.515 0.485
E11.6 With other specified complications
0.000 0.521 0.479
K90.9 Intestinal malabsorption, unspecified
0.000 0.524 0.476
E10.7 With multiple complications
0.000 0.528 0.472
E85 Amyloidosis
0.000 0.528 0.472
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.534 0.466
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.537 0.463
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.537 0.463
E70.2 Disorders of tyrosine metabolism
0.000 0.537 0.463
E70.1 Other hyperphenylalaninaemias
0.000 0.537 0.463
E70.0 Classical phenylketonuria
0.000 0.537 0.463
E10.6 With other specified complications
0.000 0.543 0.457
E88.2 Lipomatosis, not elsewhere classified
0.000 0.549 0.450
E75.2 Other sphingolipidosis
0.000 0.553 0.447
E75.6 Lipid storage disorder, unspecified
0.000 0.561 0.439
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.561 0.439
E75.3 Sphingolipidosis, unspecified
0.000 0.561 0.439
E75.1 Other gangliosidosis
0.000 0.561 0.439
E75.0 GM2 gangliosidosis
0.000 0.561 0.439
E75.5 Other lipid storage disorders
0.000 0.564 0.436
E71.3 Disorders of fatty-acid metabolism
0.000 0.564 0.435
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.564 0.435
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.564 0.435
E71.0 Maple-syrup-urine disease
0.000 0.564 0.435
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.564 0.435
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.564 0.435
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.564 0.435
E76.2 Other mucopolysaccharidoses
0.000 0.564 0.435
E76.1 Mucopolysaccharidosis, type II
0.000 0.564 0.435
E76.0 Mucopolysaccharidosis, type I
0.000 0.564 0.435
E13.3 With ophthalmic complications
0.000 0.573 0.427
E12.9 Without complications
0.000 0.576 0.423
E12.8 With unspecified complications
0.000 0.576 0.423
E12.7 With multiple complications
0.000 0.576 0.423
E12.6 With other specified complications
0.000 0.576 0.423
E12.5 With peripheral circulatory complications
0.000 0.576 0.423
E12.4 With neurological complications
0.000 0.576 0.423
E12.3 With ophthalmic complications
0.000 0.576 0.423
E12.2 With renal complications
0.000 0.576 0.423
E12.1 With ketoacidosis
0.000 0.576 0.423
E12.0 With coma
0.000 0.576 0.423
E10.4 With neurological complications
0.000 0.579 0.421
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.581 0.419
E77.1 Defects in glycoprotein degradation
0.000 0.581 0.419
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.581 0.419
E10.2 With renal complications
0.000 0.583 0.417
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.585 0.415
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.585 0.415
E72.5 Disorders of glycine metabolism
0.000 0.585 0.415
E72.4 Disorders of ornithine metabolism
0.000 0.585 0.415
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.585 0.415
E72.2 Disorders of urea cycle metabolism
0.000 0.585 0.415
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.585 0.415
E11.4 With neurological complications
0.000 0.586 0.414
E74.0 Glycogen storage disease
0.000 0.590 0.410
K90.3 Pancreatic steatorrhoea
0.000 0.591 0.409
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.591 0.409
K90.1 Tropical sprue
0.000 0.591 0.409
E13.8 With unspecified complications
0.000 0.591 0.408
E13.7 With multiple complications
0.000 0.591 0.408
E13.6 With other specified complications
0.000 0.591 0.408
E13.5 With peripheral circulatory complications
0.000 0.591 0.408
E13.4 With neurological complications
0.000 0.591 0.408
E13.2 With renal complications
0.000 0.591 0.408
E13.1 With ketoacidosis
0.000 0.591 0.408
E13.0 With coma
0.000 0.591 0.408
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.594 0.406
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.594 0.406
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.594 0.406
E74.2 Disorders of galactose metabolism
0.000 0.594 0.406
E74.1 Disorders of fructose metabolism
0.000 0.594 0.406
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.596 0.404
E77.8 Other disorders of glycoprotein metabolism
0.000 0.605 0.395
E10.3 With ophthalmic complications
0.000 0.611 0.389
E72.0 Disorders of amino-acid transport
0.000 0.614 0.386
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.625 0.374
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.625 0.374
E79.1 Lesch-Nyhan syndrome
0.000 0.625 0.374
E85.8 Other amyloidosis
0.000 0.633 0.367
E13.9 Without complications
0.000 0.636 0.364
E83.5 Disorders of calcium metabolism
0.000 0.637 0.363
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.640 0.360
E78.4 Other hyperlipidaemia
0.000 0.643 0.357
E83.4 Disorders of magnesium metabolism
0.000 0.644 0.356
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.646 0.354
E44.1 Mild protein-energy malnutrition
0.000 0.652 0.347
E44.0 Moderate protein-energy malnutrition
0.000 0.652 0.347
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.661 0.338
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.661 0.338
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.661 0.338
E78.1 Pure hyperglyceridaemia
0.000 0.662 0.338
E78.6 Lipoprotein deficiency
0.000 0.675 0.325
K90.8 Other intestinal malabsorption
0.000 0.678 0.322
E85.4 Organ-limited amyloidosis
0.000 0.679 0.320
E10.9 Without complications
0.000 0.706 0.294
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.710 0.290
E78.3 Hyperchylomicronaemia
0.000 0.718 0.282
E85.3 Secondary systemic amyloidosis
0.000 0.728 0.272
E85.9 Amyloidosis, unspecified
0.000 0.729 0.270
E65-E68 Obesity and other hyperalimentation
0.000 0.731 0.269
E00-E07 Disorders of thyroid gland
0.000 0.731 0.269
E86 Volume depletion
0.000 0.732 0.268
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.742 0.258
E06 Thyroiditis
0.000 0.745 0.255
E06.3 Autoimmune thyroiditis
0.000 0.756 0.244
E78.8 Other disorders of lipoprotein metabolism
0.000 0.767 0.233
E89.4 Postprocedural ovarian failure
0.000 0.769 0.231
C64 Malignant neoplasm of kidney, except renal pelvis
0.000 0.776 0.224
E50-E64 Other nutritional deficiencies
0.000 0.776 0.223
E06.9 Thyroiditis, unspecified
0.000 0.788 0.212
E14 Unspecified diabetes mellitus
0.000 0.795 0.205
E67 Other hyperalimentation
0.000 0.807 0.193
E68 Sequelae of hyperalimentation
0.000 0.807 0.193
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.807 0.193
E00 Congenital iodine-deficiency syndrome
0.000 0.807 0.193
E89.1 Postprocedural hypoinsulinaemia
0.000 0.813 0.187
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.815 0.185
E06.4 Drug-induced thyroiditis
0.000 0.817 0.183
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.817 0.183
E06.0 Acute thyroiditis
0.000 0.817 0.183
E78.2 Mixed hyperlipidaemia
0.000 0.821 0.179
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.822 0.178
E06.5 Other chronic thyroiditis
0.000 0.825 0.175
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.828 0.172
E58 Dietary calcium deficiency
0.000 0.834 0.166
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.834 0.165
E56 Other vitamin deficiencies
0.000 0.835 0.165
E11.3 With ophthalmic complications
0.000 0.838 0.162
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.839 0.160
E63 Other nutritional deficiencies
0.000 0.839 0.160
E50 Vitamin A deficiency
0.000 0.839 0.160
E60 Dietary zinc deficiency
0.000 0.839 0.160
E59 Dietary selenium deficiency
0.000 0.839 0.160
E52 Niacin deficiency [pellagra]
0.000 0.839 0.160
E89.2 Postprocedural hypoparathyroidism
0.000 0.840 0.160
E51 Thiamine deficiency
0.000 0.840 0.160
E89.5 Postprocedural testicular hypofunction
0.000 0.841 0.158
E14.5 With peripheral circulatory complications
0.000 0.844 0.156
E14.6 With other specified complications
0.000 0.844 0.156
E06.1 Subacute thyroiditis
0.000 0.846 0.154
E14.3 With ophthalmic complications
0.000 0.850 0.150
E14.0 With coma
0.000 0.850 0.149
E14.7 With multiple complications
0.000 0.853 0.147
E65 Localised adiposity
0.000 0.854 0.145
E03 Other hypothyroidism
0.000 0.855 0.145
E54 Ascorbic acid deficiency
0.000 0.857 0.143
E67.8 Other specified hyperalimentation
0.000 0.861 0.139
E67.3 Hypervitaminosis D
0.000 0.861 0.139
E67.2 Megavitamin-B6 syndrome
0.000 0.861 0.139
E67.1 Hypercarotenaemia
0.000 0.861 0.139
E67.0 Hypervitaminosis A
0.000 0.861 0.139
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.862 0.138
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.862 0.138
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.862 0.138
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.862 0.138
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.862 0.138
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.862 0.138
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.862 0.138
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.862 0.138
E14.1 With ketoacidosis
0.000 0.862 0.137
E14.8 With unspecified complications
0.000 0.875 0.125
E07 Other disorders of thyroid
0.000 0.876 0.124
E56.1 Deficiency of vitamin K
0.000 0.877 0.123
E61 Deficiency of other nutrient elements
0.000 0.881 0.119
E56.9 Vitamin deficiency, unspecified
0.000 0.881 0.118
E56.8 Deficiency of other vitamins
0.000 0.881 0.118
E56.0 Deficiency of vitamin E
0.000 0.881 0.118
E14.4 With neurological complications
0.000 0.884 0.116
E50.9 Vitamin A deficiency, unspecified
0.000 0.885 0.115
E50.8 Other manifestations of vitamin A deficiency
0.000 0.885 0.115
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.885 0.115
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.885 0.115
E50.5 Vitamin A deficiency with night blindness
0.000 0.885 0.115
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.885 0.115
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.885 0.115
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.885 0.115
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.885 0.115
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.885 0.115
E63.9 Nutritional deficiency, unspecified
0.000 0.885 0.115
E63.8 Other specified nutritional deficiencies
0.000 0.885 0.115
E63.1 Imbalance of constituents of food intake
0.000 0.885 0.115
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.885 0.115
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.885 0.115
E64.8 Sequelae of other nutritional deficiencies
0.000 0.885 0.115
E64.3 Sequelae of rickets
0.000 0.885 0.115
E64.2 Sequelae of vitamin C deficiency
0.000 0.885 0.115
E64.1 Sequelae of vitamin A deficiency
0.000 0.885 0.115
E64.0 Sequelae of protein-energy malnutrition
0.000 0.885 0.115
E14.2 Withrenal complications
0.000 0.885 0.115
E51.9 Thiamine deficiency, unspecified
0.000 0.885 0.115
E51.8 Other manifestations of thiamine deficiency
0.000 0.885 0.115
E51.1 Beriberi
0.000 0.885 0.115
E51.2 Wernicke's encephalopathy
0.000 0.886 0.114
E89.3 Postprocedural hypopituitarism
0.000 0.890 0.110
E20-E35 Disorders of other endocrine glands
0.000 0.891 0.109
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.891 0.109
E03.5 Myxoedema coma
0.000 0.896 0.104
E03.4 Atrophy of thyroid (acquired)
0.000 0.896 0.104
E03.3 Postinfectious hypothyroidism
0.000 0.896 0.104
E55 Vitamin D deficiency
0.000 0.899 0.101
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.900 0.100
E03.8 Other specified hypothyroidism
0.000 0.901 0.099
E53 Deficiency of other B group vitamins
0.000 0.902 0.098
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.905 0.095
E27 Other disorders of adrenal gland
0.000 0.906 0.094
E03.1 Congenital hypothyroidism without goitre
0.000 0.908 0.091
E07.1 Dyshormogenetic goitre
0.000 0.911 0.089
E07.0 Hypersecretion of calcitonin
0.000 0.911 0.089
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.911 0.089
E07.8 Other specified disorders of thyroid
0.000 0.914 0.086
E61.9 Deficiency of nutrient element, unspecified
0.000 0.915 0.085
E61.8 Deficiency of other specified nutrient elements
0.000 0.915 0.085
E61.7 Deficiency of multiple nutrient elements
0.000 0.915 0.085
E61.6 Vanadium deficiency
0.000 0.915 0.085
E61.5 Molybdenum deficiency
0.000 0.915 0.085
E61.4 Chromium deficiency
0.000 0.915 0.085
E61.3 Manganese deficiency
0.000 0.915 0.085
E61.0 Copper deficiency
0.000 0.915 0.085
E25 Adrenogenital disorders
0.000 0.915 0.085
E03.9 Hypothyroidism, unspecified
0.000 0.916 0.084
E27.1 Primary adrenocortical insufficiency
0.000 0.917 0.083
E20 Hypoparathyroidism
0.000 0.918 0.082
E31 Polyglandular dysfunction
0.000 0.921 0.079
E61.2 Magnesium deficiency
0.000 0.921 0.079
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.921 0.078
E32 Diseases of thymus
0.000 0.921 0.078
E30 Disorders of puberty, not elsewhere classified
0.000 0.921 0.078
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.922 0.078
E27.8 Other specified disorders of adrenal gland
0.000 0.927 0.073
E55.0 Rickets, active
0.000 0.927 0.072
E34 Other endocrine disorders
0.000 0.928 0.072
E53.1 Pyridoxine deficiency
0.000 0.930 0.070
E53.0 Riboflavin deficiency
0.000 0.930 0.070
E05.8 Other thyrotoxicosis
0.000 0.930 0.070
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.930 0.069
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.931 0.069
E21.2 Other hyperparathyroidism
0.000 0.931 0.069
E27.2 Addisonian crisis
0.000 0.931 0.069
E05.5 Thyroid crisis or storm
0.000 0.932 0.068
E05.4 Thyrotoxicosis factitia
0.000 0.932 0.068
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.932 0.068
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.932 0.068
E27.5 Adrenomedullary hyperfunction
0.000 0.932 0.067
E27.0 Other adrenocortical overactivity
0.000 0.932 0.067
L03.1 Cellulitis of other parts of limb
0.000 0.933 0.067
E21.0 Primary hyperparathyroidism
0.000 0.934 0.066
E53.9 Vitamin B deficiency, unspecified
0.000 0.934 0.066
E21.3 Hyperparathyroidism, unspecified
0.000 0.936 0.064
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.936 0.063
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.937 0.063
E20.9 Hypoparathyroidism, unspecified
0.000 0.938 0.062
E21.4 Other specified disorders of parathyroid gland
0.000 0.938 0.062
E25.9 Adrenogenital disorder, unspecified
0.000 0.939 0.061
E25.8 Other adrenogenital disorders
0.000 0.939 0.061
N85.0 Endometrial glandular hyperplasia
0.061 0.939 0.000
Z96.0 Presence of urogenital implants
0.000 0.940 0.060
E29 Testicular dysfunction
0.000 0.940 0.060
E28 Ovarian dysfunction
0.000 0.940 0.060
E26 Hyperaldosteronism
0.000 0.940 0.059
E20.8 Other hypoparathyroidism
0.000 0.941 0.059
E20.1 Pseudohypoparathyroidism
0.000 0.941 0.059
E20.0 Idiopathic hypoparathyroidism
0.000 0.941 0.059
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.941 0.059
E31.0 Autoimmune polyglandular failure
0.000 0.942 0.058
E31.9 Polyglandular dysfunction, unspecified
0.000 0.943 0.057
E31.8 Other polyglandular dysfunction
0.000 0.943 0.057
E31.1 Polyglandular hyperfunction
0.000 0.943 0.057
E30.9 Disorder of puberty, unspecified
0.000 0.943 0.056
E30.8 Other disorders of puberty
0.000 0.943 0.056
E30.1 Precocious puberty
0.000 0.943 0.056
E30.0 Delayed puberty
0.000 0.943 0.056
E32.9 Disease of thymus, unspecified
0.000 0.943 0.056
E32.8 Other diseases of thymus
0.000 0.943 0.056
E32.1 Abscess of thymus
0.000 0.943 0.056
E32.0 Persistent hyperplasia of thymus
0.000 0.943 0.056
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.943 0.056
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.943 0.056
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.943 0.056
E34.8 Other specified endocrine disorders
0.000 0.943 0.056
E61.1 Iron deficiency
0.000 0.944 0.056
R47.8 Other and unspecified speech disturbances
0.000 0.944 0.056
E34.3 Short stature, not elsewhere classified
0.000 0.948 0.052
D36.7 Other specified sites
0.000 0.948 0.052
E34.5 Androgen resistance syndrome
0.000 0.948 0.052
E34.4 Constitutional tall stature
0.000 0.948 0.052
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.948 0.052
E34.1 Other hypersecretion of intestinal hormones
0.000 0.948 0.052
D36.1 Peripheral nerves and autonomic nervous system
0.000 0.949 0.051
E34.9 Endocrine disorder, unspecified
0.000 0.950 0.050
D36 Benign neoplasm of other and unspecified sites
0.000 0.951 0.049
E27.9 Disorder of adrenal gland, unspecified
0.000 0.951 0.049
K90-K93 Other diseases of the digestive system
0.000 0.956 0.044
E24 Cushing's syndrome
0.000 0.957 0.043
E29.8 Other testicular dysfunction
0.000 0.957 0.043
E29.0 Testicular hyperfunction
0.000 0.957 0.043
E28.9 Ovarian dysfunction, unspecified
0.000 0.957 0.043
E28.8 Other ovarian dysfunction
0.000 0.957 0.043
E28.1 Androgen excess
0.000 0.957 0.043
E28.0 Oestrogen excess
0.000 0.957 0.043
E26.9 Hyperaldosteronism, unspecified
0.000 0.957 0.043
E26.8 Other hyperaldosteronism
0.000 0.957 0.043
E26.1 Secondary hyperaldosteronism
0.000 0.957 0.043
E28.3 Primary ovarian failure
0.000 0.957 0.043
E05.9 Thyrotoxicosis, unspecified
0.000 0.960 0.040
D36.0 Lymph nodes
0.000 0.960 0.040
R47 Speech disturbances, not elsewhere classified
0.000 0.961 0.039
E34.0 Carcinoid syndrome
0.000 0.961 0.038
E89.0 Postprocedural hypothyroidism
0.000 0.963 0.037
E29.9 Testicular dysfunction, unspecified
0.000 0.963 0.037
R47.1 Dysarthria and anarthria
0.000 0.964 0.036
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.965 0.035
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.965 0.035
C64-C68 Malignant neoplasms of urinary tract
0.000 0.965 0.035
E29.1 Testicular hypofunction
0.000 0.965 0.035
E24.2 Drug-induced Cushing's syndrome
0.000 0.967 0.032
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.000 0.967 0.033
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.968 0.032
R79.0 Abnormal level of blood mineral
0.000 0.968 0.032
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.969 0.031
E24.3 Ectopic ACTH syndrome
0.000 0.969 0.031
E24.1 Nelson's syndrome
0.000 0.969 0.031
E04 Other non-toxic goitre
0.000 0.969 0.031
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.969 0.031
E23 Hypofunction and other disorders of pituitary gland
0.000 0.969 0.030
D36.9 Benign neoplasm of unspecified site
0.000 0.970 0.029
C65 Malignant neoplasm of renal pelvis
0.000 0.971 0.029
E07.9 Disorder of thyroid, unspecified
0.000 0.971 0.029
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.972 0.028
E22 Hyperfunction of pituitary gland
0.000 0.972 0.028
E24.8 Other Cushing's syndrome
0.001 0.972 0.028
E87.5 Hyperkalaemia
0.000 0.972 0.028
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.972 0.028
E28.2 Polycystic ovarian syndrome
0.000 0.974 0.026
E87.4 Mixed disorder of acid-base balance
0.000 0.975 0.025
C68 Malignant neoplasm of other and unspecified urinary organs
0.000 0.975 0.025
E24.0 Pituitary-dependent Cushing's disease
0.001 0.976 0.024
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.000 0.976 0.024
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.000 0.976 0.024
E14.9 Without complications
0.000 0.976 0.024
E26.0 Primary hyperaldosteronism
0.001 0.977 0.023
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.977 0.023
K93.1 Megacolon in Chagas' disease
0.000 0.977 0.023
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.977 0.023
E87.3 Alkalosis
0.000 0.977 0.023
R47.0 Dysphasia and aphasia
0.000 0.977 0.023
E04.8 Other specified non-toxic goitre
0.000 0.977 0.022
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.978 0.022
E23.1 Drug-induced hypopituitarism
0.000 0.978 0.022
E22.8 Other hyperfunction of pituitary gland
0.000 0.979 0.020
B37.0 Candidal stomatitis
0.000 0.980 0.020
E87.0 Hyperosmolality and hypernatraemia
0.000 0.980 0.020
E23.6 Other disorders of pituitary gland
0.000 0.980 0.020
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.000 0.980 0.020
C68.0 Urethra
0.000 0.981 0.019
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.981 0.019
E53.8 Deficiency of other specified B group vitamins
0.000 0.981 0.019
E23.2 Diabetes insipidus
0.000 0.981 0.019
E23.7 Disorder of pituitary gland, unspecified
0.000 0.981 0.018
E66 Obesity
0.000 0.981 0.018
E22.1 Hyperprolactinaemia
0.000 0.981 0.018
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.000 0.982 0.018
C68.8 Overlapping lesion of urinary organs
0.000 0.982 0.018
C68.1 Paraurethral glands
0.000 0.982 0.018
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.982 0.018
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.982 0.018
E04.2 Non-toxic multinodular goitre
0.000 0.982 0.018
E24.9 Cushing's syndrome, unspecified
0.001 0.983 0.017
C68.9 Urinary organ, unspecified
0.000 0.983 0.017
Z57.5 Occupational exposure to toxic agents in other industries
0.017 0.983 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.983 0.016
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.016 0.984 0.000
C66 Malignant neoplasm of ureter
0.000 0.984 0.016
R47-R49 Symptoms and signs involving speech and voice
0.000 0.984 0.016
Z75.1 Person awaiting admission to adequate facility elsewhere
0.000 0.984 0.016
M05.9 Seropositive rheumatoid arthritis, unspecified
0.015 0.985 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.986 0.014
E55.9 Vitamin D deficiency, unspecified
0.001 0.986 0.013
E66.1 Drug-induced obesity
0.000 0.986 0.013
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.013 0.986 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.013 0.987 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.987 0.013
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.988 0.012
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.012 0.988 0.000
R40.0 Somnolence
0.012 0.988 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.012 0.988 0.000
E22.0 Acromegaly and pituitary gigantism
0.001 0.988 0.011
R49 Voice disturbances
0.000 0.988 0.012
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.989 0.011
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.011 0.989 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.011 0.989 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.011 0.989 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.000 0.989 0.011
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.011 0.989 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.010 0.989 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.990 0.010
M05 Seropositive rheumatoid arthritis
0.010 0.990 0.000
R18 Ascites
0.000 0.990 0.010
R49.0 Dysphonia
0.000 0.991 0.009
K91.4 Colostomy and enterostomy malfunction
0.000 0.991 0.009
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.991 0.009
K91.3 Postoperative intestinal obstruction
0.000 0.991 0.009
E04.9 Non-toxic goitre, unspecified
0.000 0.991 0.009
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.991 0.009
R49.1 Aphonia
0.000 0.991 0.009
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.001 0.991 0.008
R49.2 Hypernasality and hyponasality
0.000 0.991 0.009
M05.2 Rheumatoid vasculitis
0.008 0.992 0.000
R48.8 Other and unspecified symbolic dysfunctions
0.000 0.992 0.008
R48.2 Apraxia
0.000 0.992 0.008
R48.1 Agnosia
0.000 0.992 0.008
M05.8 Other seropositive rheumatoid arthritis
0.008 0.992 0.000
K91.1 Postgastric surgery syndromes
0.000 0.992 0.008
M05.0 Felty's syndrome
0.008 0.992 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.992 0.008
R48.0 Dyslexia and alexia
0.000 0.992 0.007
K91.5 Postcholecystectomy syndrome
0.000 0.992 0.007
Z75 Problems related to medical facilities and other health care
0.000 0.993 0.007
E66.0 Obesity due to excess calories
0.001 0.993 0.007
R49.8 Other and unspecified voice disturbances
0.000 0.993 0.007
M05.29 Rheumatoid vasculitis (Site unspecified)
0.007 0.993 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.007 0.993 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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