TreeWAS – Variant ID: rs9357123

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M45.X9 Ankylosing spondylitis (Site unspecified)	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.000	1.000
E00-E07 Disorders of thyroid gland	0.000	0.001	0.999
M06.9 Rheumatoid arthritis, unspecified	0.999	0.001	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.999	0.001	0.000
M06 Other rheumatoid arthritis	0.998	0.002	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.004	0.996
M45 Ankylosing spondylitis	0.996	0.004	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.007	0.993
E10-E14 Diabetes mellitus	0.000	0.007	0.993
M05-M14 Inflammatory polyarthropathies	0.989	0.011	0.000
E10.9 Without complications	0.000	0.023	0.977
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.975	0.025	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.033	0.967
M45-M49 Spondylopathies	0.957	0.043	0.000
M06.0 Seronegative rheumatoid arthritis	0.954	0.046	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.952	0.048	0.000
M07 Psoriatic and enteropathic arthropathies	0.950	0.050	0.000
E10.1 With ketoacidosis	0.000	0.054	0.946
M07.3 Other psoriatic arthropathies	0.922	0.078	0.000
E10.3 With ophthalmic complications	0.000	0.079	0.921
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.905	0.095	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.898	0.102	0.000
K90.0 Coeliac disease	0.000	0.108	0.892
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.112	0.888
E05.9 Thyrotoxicosis, unspecified	0.000	0.116	0.884
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.883	0.117	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.133	0.867
M07.30 Other psoriatic arthropathies (Multiple sites)	0.867	0.133	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.866	0.134	0.000
E10.4 With neurological complications	0.000	0.136	0.864
E50-E64 Other nutritional deficiencies	0.000	0.141	0.859
E70-E90 Metabolic disorders	0.000	0.151	0.849
E04 Other non-toxic goitre	0.000	0.152	0.848
M05 Seropositive rheumatoid arthritis	0.840	0.160	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.814	0.186	0.000
M06.4 Inflammatory polyarthropathy	0.803	0.197	0.000
E07 Other disorders of thyroid	0.000	0.198	0.802
M14 Arthropathies in other diseases classified elsewhere	0.788	0.211	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.216	0.784
E10.5 With peripheral circulatory complications	0.000	0.222	0.778
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.777	0.223	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.772	0.228	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.771	0.229	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.768	0.232	0.000
E06 Thyroiditis	0.000	0.236	0.764
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.762	0.238	0.000
E55 Vitamin D deficiency	0.000	0.243	0.756
M06.3 Rheumatoid nodule	0.755	0.245	0.000
M00-M03 Infectious arthropathies	0.754	0.246	0.000
E27 Other disorders of adrenal gland	0.000	0.256	0.744
E13 Other specified diabetes mellitus	0.000	0.263	0.737
E40-E46 Malnutrition	0.000	0.264	0.736
M45.X2 Ankylosing spondylitis (Cervical region)	0.735	0.265	0.000
M80-M85 Disorders of bone density and structure	0.734	0.266	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.733	0.267	0.000
E21.0 Primary hyperparathyroidism	0.000	0.268	0.732
E04.2 Non-toxic multinodular goitre	0.000	0.268	0.732
M60-M63 Disorders of muscles	0.723	0.277	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.278	0.722
E03.5 Myxoedema coma	0.000	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.000	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.000	0.283	0.717
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.283	0.717
E03.1 Congenital hypothyroidism without goitre	0.000	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.717
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.283	0.717
M06.98 Rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.716	0.284	0.000
M06.2 Rheumatoid bursitis	0.716	0.284	0.000
M06.1 Adult-onset Still's disease	0.716	0.284	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.714	0.286	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.714	0.286	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.714	0.286	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.714	0.286	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.714	0.286	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.714	0.286	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.714	0.286	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.286	0.714
E10.8 With unspecified complications	0.000	0.288	0.712
E10.7 With multiple complications	0.000	0.288	0.712
E10.0 With coma	0.000	0.288	0.712
E12 Malnutrition-related diabetes mellitus	0.000	0.288	0.712
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.288	0.712
E04.1 Non-toxic single thyroid nodule	0.000	0.289	0.711
M12 Other specific arthropathies	0.709	0.291	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.709	0.291	0.000
M08 Juvenile arthritis	0.709	0.291	0.000
E22 Hyperfunction of pituitary gland	0.000	0.297	0.703
M86-M90 Other osteopathies	0.701	0.299	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.300	0.700
E27.1 Primary adrenocortical insufficiency	0.000	0.302	0.698
E83 Disorders of mineral metabolism	0.000	0.304	0.696
E87.6 Hypokalaemia	0.000	0.304	0.696
E05.8 Other thyrotoxicosis	0.000	0.307	0.693
E05.5 Thyroid crisis or storm	0.000	0.307	0.693
E05.4 Thyrotoxicosis factitia	0.000	0.307	0.693
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.307	0.693
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.307	0.693
M91-M94 Chondropathies	0.688	0.312	0.000
M49 Spondylopathies in diseases classified elsewhere	0.686	0.314	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.684	0.316	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.684	0.316	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.684	0.316	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.684	0.316	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.684	0.316	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.684	0.316	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.684	0.316	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.684	0.316	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.317	0.683
E07.9 Disorder of thyroid, unspecified	0.000	0.317	0.683
M07.6 Other enteropathic arthropathies	0.681	0.319	0.000
M07.5 Arthropathy in ulcerative colitis	0.681	0.319	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.681	0.319	0.000
M07.2 Psoriatic spondylitis	0.681	0.319	0.000
M07.1 Arthritis mutilans	0.681	0.319	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.681	0.319	0.000
E88 Other metabolic disorders	0.000	0.321	0.679
M11 Other crystal arthropathies	0.675	0.324	0.000
E03.8 Other specified hypothyroidism	0.000	0.326	0.674
E10.2 With renal complications	0.000	0.326	0.674
M20-M25 Other joint disorders	0.672	0.328	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.668	0.331	0.000
M07.38 Other psoriatic arthropathies (Other)	0.661	0.339	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.661	0.339	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.661	0.339	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.661	0.339	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.661	0.339	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.661	0.339	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.661	0.339	0.000
E53 Deficiency of other B group vitamins	0.000	0.342	0.658
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.657	0.342	0.000
M80 Osteoporosis with pathological fracture	0.647	0.353	0.000
M14.6 Neuropathic arthropathy	0.645	0.355	0.000
M40-M43 Deforming dorsopathies	0.640	0.360	0.000
E73 Lactose intolerance	0.000	0.363	0.637
E14 Unspecified diabetes mellitus	0.000	0.372	0.628
E85 Amyloidosis	0.000	0.373	0.626
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.378	0.622
E32 Diseases of thymus	0.000	0.378	0.622
E31 Polyglandular dysfunction	0.000	0.378	0.622
E30 Disorders of puberty, not elsewhere classified	0.000	0.378	0.622
E26 Hyperaldosteronism	0.000	0.378	0.622
E25 Adrenogenital disorders	0.000	0.378	0.622
M02 Reactive arthropathies	0.621	0.379	0.000
E10.6 With other specified complications	0.000	0.381	0.619
E20 Hypoparathyroidism	0.000	0.382	0.618
E34 Other endocrine disorders	0.000	0.382	0.618
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.384	0.616
E63 Other nutritional deficiencies	0.000	0.384	0.616
E56 Other vitamin deficiencies	0.000	0.384	0.616
E51 Thiamine deficiency	0.000	0.384	0.616
E50 Vitamin A deficiency	0.000	0.384	0.616
E60 Dietary zinc deficiency	0.000	0.384	0.616
E59 Dietary selenium deficiency	0.000	0.384	0.616
E58 Dietary calcium deficiency	0.000	0.384	0.616
E54 Ascorbic acid deficiency	0.000	0.384	0.616
E52 Niacin deficiency [pellagra]	0.000	0.384	0.616
E83.5 Disorders of calcium metabolism	0.000	0.388	0.612
E74 Other disorders of carbohydrate metabolism	0.000	0.391	0.609
E84 Cystic fibrosis	0.000	0.391	0.609
E79 Disorders of purine and pyrimidine metabolism	0.000	0.391	0.609
E77 Disorders of glycoprotein metabolism	0.000	0.391	0.609
E76 Disorders of glycosaminoglycan metabolism	0.000	0.391	0.609
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.391	0.609
E72 Other disorders of amino-acid metabolism	0.000	0.391	0.609
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.391	0.609
E70 Disorders of aromatic amino-acid metabolism	0.000	0.391	0.609
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.391	0.609
E04.8 Other specified non-toxic goitre	0.000	0.392	0.608
E04.0 Non-toxic diffuse goitre	0.000	0.397	0.602
M05.8 Other seropositive rheumatoid arthritis	0.602	0.398	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.602	0.398	0.000
M05.2 Rheumatoid vasculitis	0.602	0.398	0.000
M05.1 Rheumatoid lung disease	0.602	0.398	0.000
M05.0 Felty's syndrome	0.602	0.398	0.000
M24 Other specific joint derangements	0.601	0.399	0.000
E87.0 Hyperosmolality and hypernatraemia	0.000	0.400	0.599
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.597	0.403	0.000
M34 Systemic sclerosis	0.596	0.404	0.000
E06.3 Autoimmune thyroiditis	0.000	0.405	0.595
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.593	0.407	0.000
M46 Other inflammatory spondylopathies	0.592	0.407	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.588	0.412	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.586	0.414	0.000
M06.34 Rheumatoid nodule (Hand)	0.580	0.419	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.576	0.424	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.576	0.424	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.576	0.424	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.576	0.424	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.576	0.424	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.576	0.424	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.576	0.424	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.576	0.424	0.000
E89.3 Postprocedural hypopituitarism	0.000	0.424	0.576
E07.1 Dyshormogenetic goitre	0.000	0.425	0.575
E07.0 Hypersecretion of calcitonin	0.000	0.425	0.575
E61 Deficiency of other nutrient elements	0.000	0.425	0.574
E24 Cushing's syndrome	0.000	0.427	0.573
E89.2 Postprocedural hypoparathyroidism	0.000	0.427	0.573
E87.5 Hyperkalaemia	0.000	0.430	0.570
M10 Gout	0.569	0.431	0.000
M85 Other disorders of bone density and structure	0.567	0.433	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.565	0.435	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.565	0.435	0.000
M14.4 Arthropathy in amyloidosis	0.565	0.435	0.000
M14.3 Lipoid dermatoarthritis	0.565	0.435	0.000
M14.2 Diabetic arthropathy	0.565	0.435	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.565	0.435	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.565	0.435	0.000
E86 Volume depletion	0.000	0.436	0.564
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.437	0.562
E21.4 Other specified disorders of parathyroid gland	0.000	0.437	0.562
E21.2 Other hyperparathyroidism	0.000	0.437	0.562
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.437	0.562
M21 Other acquired deformities of limbs	0.560	0.440	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.560	0.440	0.000
M62 Other disorders of muscle	0.559	0.441	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.443	0.557
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.443	0.557
E28 Ovarian dysfunction	0.000	0.443	0.557
E13.9 Without complications	0.000	0.447	0.553
M89 Other disorders of bone	0.551	0.449	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.450	0.550
E46 Unspecified protein-energy malnutrition	0.000	0.450	0.550
E06.9 Thyroiditis, unspecified	0.000	0.452	0.548
E06.5 Other chronic thyroiditis	0.000	0.452	0.548
E06.4 Drug-induced thyroiditis	0.000	0.452	0.548
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.452	0.548
E06.1 Subacute thyroiditis	0.000	0.452	0.548
E06.0 Acute thyroiditis	0.000	0.452	0.548
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.456	0.544
E55.0 Rickets, active	0.000	0.457	0.542
E29 Testicular dysfunction	0.000	0.458	0.542
M06.39 Rheumatoid nodule (Site unspecified)	0.541	0.459	0.000
M06.38 Rheumatoid nodule (Other)	0.541	0.459	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.541	0.459	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.541	0.459	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.541	0.459	0.000
M06.33 Rheumatoid nodule (Forearm)	0.541	0.459	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.541	0.459	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.541	0.459	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.541	0.459	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.541	0.459	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.541	0.459	0.000
M92 Other juvenile osteochondrosis	0.538	0.461	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.467	0.533
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.467	0.533
E27.2 Addisonian crisis	0.000	0.467	0.533
E27.0 Other adrenocortical overactivity	0.000	0.467	0.533
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.532	0.467	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.467	0.533
E07.8 Other specified disorders of thyroid	0.000	0.469	0.531
M80.9 Unspecified osteoporosis with pathological fracture	0.531	0.469	0.000
M34.9 Systemic sclerosis, unspecified	0.531	0.469	0.000
E13.8 With unspecified complications	0.000	0.471	0.528
E13.7 With multiple complications	0.000	0.471	0.528
E13.6 With other specified complications	0.000	0.471	0.528
E13.5 With peripheral circulatory complications	0.000	0.471	0.528
E13.4 With neurological complications	0.000	0.471	0.528
E13.3 With ophthalmic complications	0.000	0.471	0.528
E13.2 With renal complications	0.000	0.471	0.528
E13.1 With ketoacidosis	0.000	0.471	0.528
E13.0 With coma	0.000	0.471	0.528
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.472	0.528
E45 Retarded development following protein-energy malnutrition	0.000	0.472	0.528
E43 Unspecified severe protein-energy malnutrition	0.000	0.472	0.528
E42 Marasmic kwashiorkor	0.000	0.472	0.528
E41 Nutritional marasmus	0.000	0.472	0.528
E40 Kwashiorkor	0.000	0.472	0.528
M83 Adult osteomalacia	0.526	0.473	0.000
M82 Osteoporosis in diseases classified elsewhere	0.526	0.473	0.000
M00 Pyogenic arthritis	0.526	0.474	0.000
M02.3 Reiter's disease	0.526	0.474	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.525	0.474	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.525	0.474	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.525	0.474	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.525	0.474	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.525	0.474	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.525	0.474	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.525	0.474	0.000
M86 Osteomyelitis	0.522	0.478	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.479	0.521
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.521	0.479	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.518	0.481	0.000
M61 Calcification and ossification of muscle	0.518	0.481	0.000
M60 Myositis	0.518	0.481	0.000
E87.4 Mixed disorder of acid-base balance	0.000	0.482	0.518
M50-M54 Other dorsopathies	0.517	0.483	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.486	0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.486	0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.486	0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.486	0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.486	0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.486	0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.486	0.514
E53.8 Deficiency of other specified B group vitamins	0.000	0.486	0.514
M06.19 Adult-onset Still's disease (Site unspecified)	0.513	0.487	0.000
M06.18 Adult-onset Still's disease (Other)	0.513	0.487	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.513	0.487	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.513	0.487	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.513	0.487	0.000
M06.14 Adult-onset Still's disease (Hand)	0.513	0.487	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.513	0.487	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.513	0.487	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.513	0.487	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.513	0.487	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.513	0.487	0.000
M06.28 Rheumatoid bursitis (Other)	0.513	0.487	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.513	0.487	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.513	0.487	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.513	0.487	0.000
M06.24 Rheumatoid bursitis (Hand)	0.513	0.487	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.513	0.487	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.513	0.487	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.513	0.487	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.513	0.487	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.513	0.487	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.513	0.487	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.513	0.487	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.513	0.487	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.513	0.487	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.513	0.487	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.513	0.487	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.513	0.487	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.513	0.487	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.513	0.487	0.000
M40 Kyphosis and lordosis	0.512	0.488	0.000
E15 Nondiabetic hypoglycaemic coma	0.000	0.488	0.512
E16 Other disorders of pancreatic internal secretion	0.000	0.488	0.512
E12.9 Without complications	0.000	0.489	0.511
E12.8 With unspecified complications	0.000	0.489	0.511
E12.7 With multiple complications	0.000	0.489	0.511
E12.6 With other specified complications	0.000	0.489	0.511
E12.5 With peripheral circulatory complications	0.000	0.489	0.511
E12.4 With neurological complications	0.000	0.489	0.511
E12.3 With ophthalmic complications	0.000	0.489	0.511
E12.2 With renal complications	0.000	0.489	0.511
E12.1 With ketoacidosis	0.000	0.489	0.511
E12.0 With coma	0.000	0.489	0.511
M90 Osteopathies in diseases classified elsewhere	0.510	0.489	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.490	0.510
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.490	0.510
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.490	0.510
E89.5 Postprocedural testicular hypofunction	0.000	0.490	0.510
E89.4 Postprocedural ovarian failure	0.000	0.490	0.510
E89.1 Postprocedural hypoinsulinaemia	0.000	0.490	0.510
M20 Acquired deformities of fingers and toes	0.510	0.490	0.000
M08.9 Juvenile arthritis, unspecified	0.508	0.491	0.000
M08.8 Other juvenile arthritis	0.508	0.491	0.000
M08.4 Pauciarticular juvenile arthritis	0.508	0.491	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.508	0.491	0.000
M08.2 Juvenile arthritis with systemic onset	0.508	0.491	0.000
M08.1 Juvenile ankylosing spondylitis	0.508	0.491	0.000
M08.0 Juvenile rheumatoid arthritis	0.508	0.491	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.508	0.491	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.508	0.491	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.508	0.491	0.000
M09.0 Juvenile arthritis in psoriasis	0.508	0.491	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.508	0.491	0.000
M12.5 Traumatic arthropathy	0.508	0.491	0.000
M12.4 Intermittent hydrarthrosis	0.508	0.491	0.000
M12.3 Palindromic rheumatism	0.508	0.491	0.000
M12.2 Villonodular synovitis (pigmented)	0.508	0.491	0.000
M12.1 Kaschin-Beck disease	0.508	0.491	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.508	0.491	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.495	0.505
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.496	0.504
E22.8 Other hyperfunction of pituitary gland	0.000	0.496	0.504
E22.1 Hyperprolactinaemia	0.000	0.496	0.504
M80.0 Postmenopausal osteoporosis with pathological fracture	0.503	0.497	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.500	0.500
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.501	0.499
E83.8 Other disorders of mineral metabolism	0.000	0.501	0.499
E83.2 Disorders of zinc metabolism	0.000	0.501	0.499
E83.0 Disorders of copper metabolism	0.000	0.501	0.499
M24.8 Other specific joint derangements, not elsewhere classified	0.494	0.506	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.493	0.507	0.000
M49.8 Spondylopathy in other diseases classified elsewhere	0.492	0.508	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.492	0.508	0.000
M49.4 Neuropathic spondylopathy	0.492	0.508	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.492	0.508	0.000
M49.2 Enterobacterial spondylitis	0.492	0.508	0.000
M49.1 Brucella spondylitis	0.492	0.508	0.000
M49.0 Tuberculosis of spine	0.492	0.508	0.000
M24.0 Loose body in joint	0.491	0.509	0.000
M88 Paget's disease of bone [osteitis deformans]	0.490	0.510	0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.488	0.511	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.488	0.511	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.488	0.511	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.488	0.511	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.488	0.511	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.488	0.511	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.488	0.511	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.488	0.511	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.488	0.511	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.488	0.511	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.488	0.511	0.000
M07.18 Arthritis mutilans (Other)	0.488	0.511	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.488	0.511	0.000
M07.16 Arthritis mutilans (Lower leg)	0.488	0.511	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.488	0.511	0.000
M07.14 Arthritis mutilans (Hand)	0.488	0.511	0.000
M07.13 Arthritis mutilans (Forearm)	0.488	0.511	0.000
M07.12 Arthritis mutilans (Upper arm)	0.488	0.511	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.488	0.511	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.488	0.511	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.488	0.511	0.000
M07.28 Psoriatic spondylitis (Other)	0.488	0.511	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.488	0.511	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.488	0.511	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.488	0.511	0.000
M07.24 Psoriatic spondylitis (Hand)	0.488	0.511	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.488	0.511	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.488	0.511	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.488	0.511	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.488	0.511	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.488	0.511	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.488	0.511	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.488	0.511	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.488	0.511	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.488	0.511	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.488	0.511	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.488	0.511	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.488	0.511	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.488	0.511	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.488	0.511	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.488	0.511	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.488	0.511	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.488	0.511	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.488	0.511	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.488	0.511	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.488	0.511	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.488	0.511	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.488	0.511	0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.488	0.511	0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.488	0.511	0.000
M07.69 Other enteropathic arthropathies (Site unspecified)	0.488	0.511	0.000
M07.68 Other enteropathic arthropathies (Other)	0.488	0.511	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.488	0.511	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.488	0.511	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.488	0.511	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.488	0.511	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.488	0.511	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.488	0.511	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.488	0.511	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.488	0.511	0.000
E88.9 Metabolic disorder, unspecified	0.000	0.513	0.487
E88.8 Other specified metabolic disorders	0.000	0.513	0.487
E88.3 Tumour lysis syndrome	0.000	0.513	0.487
E88.2 Lipomatosis, not elsewhere classified	0.000	0.513	0.487
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.513	0.487
E73.9 Lactose intolerance, unspecified	0.000	0.514	0.486
E27.8 Other specified disorders of adrenal gland	0.000	0.515	0.485
M11.9 Crystal arthropathy, unspecified	0.484	0.515	0.000
M11.8 Other specified crystal arthropathies	0.484	0.515	0.000
M11.1 Familial chondrocalcinosis	0.484	0.515	0.000
M11.0 Hydroxyapatite deposition disease	0.484	0.515	0.000
M30 Polyarteritis nodosa and related conditions	0.482	0.518	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.482	0.518	0.000
M33 Dermatopolymyositis	0.482	0.518	0.000
M32 Systemic lupus erythematosus	0.482	0.518	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.476	0.524	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.474	0.526	0.000
M94 Other disorders of cartilage	0.474	0.526	0.000
M84 Disorders of continuity of bone	0.473	0.527	0.000
M31 Other necrotising vasculopathies	0.473	0.527	0.000
E53.9 Vitamin B deficiency, unspecified	0.000	0.528	0.472
E53.1 Pyridoxine deficiency	0.000	0.528	0.472
E53.0 Riboflavin deficiency	0.000	0.528	0.472
E23 Hypofunction and other disorders of pituitary gland	0.000	0.530	0.469
M23 Internal derangement of knee	0.468	0.532	0.000
M50 Cervical disk disorders	0.468	0.532	0.000
M24.6 Ankylosis of joint	0.467	0.533	0.000
E85.4 Organ-limited amyloidosis	0.000	0.533	0.467
E14.9 Without complications	0.000	0.533	0.467
M93 Other osteochondropathies	0.464	0.536	0.000
M80.8 Other osteoporosis with pathological fracture	0.464	0.536	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.464	0.536	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.464	0.536	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.464	0.536	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.464	0.536	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.539	0.460
M42 Spinal osteochondrosis	0.459	0.541	0.000
M85.0 Fibrous dysplasia (monostotic)	0.458	0.542	0.000
M02.39 Reiter's disease (Site unspecified)	0.458	0.542	0.000
E73.8 Other lactose intolerance	0.000	0.543	0.457
E73.1 Secondary lactase deficiency	0.000	0.543	0.457
E73.0 Congenital lactase deficiency	0.000	0.543	0.457
E87.3 Alkalosis	0.000	0.544	0.456
M34.8 Other forms of systemic sclerosis	0.454	0.545	0.000
M11.2 Other chondrocalcinosis	0.451	0.549	0.000
E14.8 With unspecified complications	0.000	0.549	0.450
E14.7 With multiple complications	0.000	0.549	0.450
E14.6 With other specified complications	0.000	0.549	0.450
E14.5 With peripheral circulatory complications	0.000	0.549	0.450

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations