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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9366078
log Bayes Factor = 24.9988
Chromosome 6   position 167,399,512  (GRCh37) Explore rs9366078 on Ensembl!
Variant rs9366078 is part of Cluster X0108

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.002 0.998
E10 Insulin-dependent diabetes mellitus
0.000 0.002 0.998
C44.3 Skin of other and unspecified parts of face
0.997 0.003 0.000
E50-E64 Other nutritional deficiencies
0.000 0.009 0.991
E05.9 Thyrotoxicosis, unspecified
0.000 0.009 0.991
E14 Unspecified diabetes mellitus
0.000 0.011 0.989
E53 Deficiency of other B group vitamins
0.000 0.013 0.987
E53.8 Deficiency of other specified B group vitamins
0.000 0.016 0.984
E10.9 Without complications
0.000 0.021 0.979
C44 Other malignant neoplasms of skin
0.966 0.034 0.000
E10.4 With neurological complications
0.000 0.035 0.965
C44.5 Skin of trunk
0.961 0.039 0.000
E14.9 Without complications
0.000 0.041 0.959
E07 Other disorders of thyroid
0.000 0.046 0.954
E07.9 Disorder of thyroid, unspecified
0.000 0.071 0.929
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.081 0.919
C43-C44 Melanoma and other malignant neoplasms of skin
0.890 0.110 0.000
E14.4 With neurological complications
0.000 0.111 0.889
E10.2 With renal complications
0.000 0.124 0.876
C43 Malignant melanoma of skin
0.875 0.125 0.000
E10.1 With ketoacidosis
0.000 0.126 0.874
C43.5 Malignant melanoma of trunk
0.865 0.135 0.000
E03.8 Other specified hypothyroidism
0.000 0.148 0.852
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.153 0.847
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.169 0.831
E10.0 With coma
0.000 0.194 0.806
C44.6 Skin of upper limb, including shoulder
0.800 0.200 0.000
E14.3 With ophthalmic complications
0.000 0.224 0.776
C43.3 Malignant melanoma of other and unspecified parts of face
0.775 0.225 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.226 0.774
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.237 0.763
E51 Thiamine deficiency
0.000 0.245 0.754
E14.5 With peripheral circulatory complications
0.000 0.255 0.745
E14.8 With unspecified complications
0.000 0.255 0.745
E14.2 Withrenal complications
0.000 0.263 0.737
E61 Deficiency of other nutrient elements
0.000 0.263 0.737
C43.9 Malignant melanoma of skin, unspecified
0.736 0.264 0.000
E10.6 With other specified complications
0.000 0.272 0.728
C43.1 Malignant melanoma of eyelid, including canthus
0.723 0.277 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E10.7 With multiple complications
0.000 0.285 0.715
C44.0 Skin of lip
0.712 0.288 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.290 0.710
E63 Other nutritional deficiencies
0.000 0.290 0.710
E50 Vitamin A deficiency
0.000 0.290 0.710
E60 Dietary zinc deficiency
0.000 0.290 0.710
E59 Dietary selenium deficiency
0.000 0.290 0.710
E58 Dietary calcium deficiency
0.000 0.290 0.710
E54 Ascorbic acid deficiency
0.000 0.290 0.710
E52 Niacin deficiency [pellagra]
0.000 0.290 0.710
E16 Other disorders of pancreatic internal secretion
0.000 0.290 0.710
E14.7 With multiple complications
0.000 0.291 0.709
E14.0 With coma
0.000 0.291 0.709
E53.1 Pyridoxine deficiency
0.000 0.292 0.708
E53.0 Riboflavin deficiency
0.000 0.292 0.708
C44.9 Malignant neoplasm of skin, unspecified
0.695 0.305 0.000
C44.8 Overlapping lesion of skin
0.693 0.307 0.000
E14.1 With ketoacidosis
0.000 0.312 0.688
E07.1 Dyshormogenetic goitre
0.000 0.316 0.684
E07.0 Hypersecretion of calcitonin
0.000 0.316 0.684
E56 Other vitamin deficiencies
0.000 0.325 0.675
E14.6 With other specified complications
0.000 0.348 0.652
E16.2 Hypoglycaemia, unspecified
0.000 0.357 0.643
E05.8 Other thyrotoxicosis
0.000 0.362 0.638
E10.8 With unspecified complications
0.000 0.362 0.637
C43.8 Overlapping malignant melanoma of skin
0.627 0.373 0.000
C43.0 Malignant melanoma of lip
0.627 0.373 0.000
C43.4 Malignant melanoma of scalp and neck
0.611 0.389 0.000
E07.8 Other specified disorders of thyroid
0.000 0.395 0.605
E40-E46 Malnutrition
0.000 0.399 0.601
E15 Nondiabetic hypoglycaemic coma
0.000 0.404 0.596
C44.2 Skin of ear and external auricular canal
0.589 0.411 0.000
E51.2 Wernicke's encephalopathy
0.000 0.415 0.585
E61.2 Magnesium deficiency
0.000 0.428 0.572
E10.3 With ophthalmic complications
0.000 0.429 0.571
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.436 0.563
C43.6 Malignant melanoma of upper limb, including shoulder
0.556 0.444 0.000
E13 Other specified diabetes mellitus
0.000 0.446 0.554
E06 Thyroiditis
0.000 0.453 0.547
E51.9 Thiamine deficiency, unspecified
0.000 0.459 0.541
E51.8 Other manifestations of thiamine deficiency
0.000 0.459 0.541
E51.1 Beriberi
0.000 0.459 0.541
E65-E68 Obesity and other hyperalimentation
0.000 0.463 0.537
E61.9 Deficiency of nutrient element, unspecified
0.000 0.472 0.528
E61.8 Deficiency of other specified nutrient elements
0.000 0.472 0.528
E61.7 Deficiency of multiple nutrient elements
0.000 0.472 0.528
E61.6 Vanadium deficiency
0.000 0.472 0.528
E61.5 Molybdenum deficiency
0.000 0.472 0.528
E61.4 Chromium deficiency
0.000 0.472 0.528
E61.3 Manganese deficiency
0.000 0.472 0.528
E61.0 Copper deficiency
0.000 0.472 0.528
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.478 0.522
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.513
E12.8 With unspecified complications
0.000 0.486 0.513
E12.7 With multiple complications
0.000 0.486 0.513
E12.6 With other specified complications
0.000 0.486 0.513
E12.5 With peripheral circulatory complications
0.000 0.486 0.513
E12.4 With neurological complications
0.000 0.486 0.513
E12.3 With ophthalmic complications
0.000 0.486 0.513
E12.2 With renal complications
0.000 0.486 0.513
E12.1 With ketoacidosis
0.000 0.486 0.513
E12.0 With coma
0.000 0.486 0.513
E50.9 Vitamin A deficiency, unspecified
0.000 0.491 0.509
E50.8 Other manifestations of vitamin A deficiency
0.000 0.491 0.509
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.491 0.509
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.491 0.509
E50.5 Vitamin A deficiency with night blindness
0.000 0.491 0.509
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.491 0.509
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.491 0.509
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.491 0.509
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.491 0.509
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.491 0.509
E63.9 Nutritional deficiency, unspecified
0.000 0.491 0.509
E63.8 Other specified nutritional deficiencies
0.000 0.491 0.509
E63.1 Imbalance of constituents of food intake
0.000 0.491 0.509
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.491 0.509
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.491 0.509
E64.8 Sequelae of other nutritional deficiencies
0.000 0.491 0.509
E64.3 Sequelae of rickets
0.000 0.491 0.509
E64.2 Sequelae of vitamin C deficiency
0.000 0.491 0.509
E64.1 Sequelae of vitamin A deficiency
0.000 0.491 0.509
E64.0 Sequelae of protein-energy malnutrition
0.000 0.491 0.509
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.491 0.509
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.491 0.509
E16.4 Abnormal secretion of gastrin
0.000 0.491 0.509
E16.3 Increased secretion of glucagon
0.000 0.491 0.509
E61.1 Iron deficiency
0.000 0.494 0.506
E10.5 With peripheral circulatory complications
0.000 0.507 0.492
E56.9 Vitamin deficiency, unspecified
0.000 0.516 0.484
E56.8 Deficiency of other vitamins
0.000 0.516 0.484
E56.0 Deficiency of vitamin E
0.000 0.516 0.484
E55 Vitamin D deficiency
0.000 0.549 0.451
E56.1 Deficiency of vitamin K
0.000 0.551 0.449
E16.1 Other hypoglycaemia
0.000 0.566 0.434
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.569 0.431
E45 Retarded development following protein-energy malnutrition
0.000 0.569 0.431
E43 Unspecified severe protein-energy malnutrition
0.000 0.569 0.431
E42 Marasmic kwashiorkor
0.000 0.569 0.431
E41 Nutritional marasmus
0.000 0.569 0.431
E40 Kwashiorkor
0.000 0.569 0.431
C43.2 Malignant melanoma of ear and external auricular canal
0.421 0.578 0.001
E13.8 With unspecified complications
0.000 0.602 0.397
E13.7 With multiple complications
0.000 0.602 0.397
E13.6 With other specified complications
0.000 0.602 0.397
E13.5 With peripheral circulatory complications
0.000 0.602 0.397
E13.4 With neurological complications
0.000 0.602 0.397
E13.2 With renal complications
0.000 0.602 0.397
E13.1 With ketoacidosis
0.000 0.602 0.397
E13.0 With coma
0.000 0.602 0.397
E06.3 Autoimmune thyroiditis
0.000 0.606 0.394
E06.5 Other chronic thyroiditis
0.000 0.608 0.392
E06.4 Drug-induced thyroiditis
0.000 0.608 0.392
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.608 0.392
E06.0 Acute thyroiditis
0.000 0.608 0.392
E67 Other hyperalimentation
0.000 0.615 0.385
E68 Sequelae of hyperalimentation
0.000 0.615 0.385
E66 Obesity
0.000 0.622 0.378
E13.3 With ophthalmic complications
0.000 0.627 0.373
C44.1 Skin of eyelid, including canthus
0.370 0.630 0.000
E06.1 Subacute thyroiditis
0.000 0.652 0.348
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.656 0.344
E55.0 Rickets, active
0.000 0.676 0.323
E46 Unspecified protein-energy malnutrition
0.000 0.684 0.316
E44.1 Mild protein-energy malnutrition
0.000 0.691 0.309
E44.0 Moderate protein-energy malnutrition
0.000 0.691 0.309
E66.8 Other obesity
0.000 0.698 0.302
E06.9 Thyroiditis, unspecified
0.000 0.709 0.291
C44.7 Skin of lower limb, including hip
0.281 0.719 0.000
E13.9 Without complications
0.000 0.722 0.278
E67.8 Other specified hyperalimentation
0.000 0.724 0.276
E67.3 Hypervitaminosis D
0.000 0.724 0.276
E67.2 Megavitamin-B6 syndrome
0.000 0.724 0.276
E67.1 Hypercarotenaemia
0.000 0.724 0.276
E67.0 Hypervitaminosis A
0.000 0.724 0.276
E66.1 Drug-induced obesity
0.000 0.729 0.271
E04 Other non-toxic goitre
0.000 0.735 0.265
L43.9 Lichen planus, unspecified
0.000 0.750 0.250
E20-E35 Disorders of other endocrine glands
0.000 0.755 0.245
E66.0 Obesity due to excess calories
0.000 0.764 0.236
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.774 0.226
E65 Localised adiposity
0.001 0.781 0.219
E21.3 Hyperparathyroidism, unspecified
0.000 0.792 0.208
E04.0 Non-toxic diffuse goitre
0.000 0.794 0.206
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.808 0.192
E04.8 Other specified non-toxic goitre
0.000 0.810 0.190
E25 Adrenogenital disorders
0.000 0.817 0.183
E26 Hyperaldosteronism
0.000 0.824 0.176
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.824 0.176
E32 Diseases of thymus
0.000 0.824 0.176
E31 Polyglandular dysfunction
0.000 0.824 0.176
E30 Disorders of puberty, not elsewhere classified
0.000 0.824 0.176
E28 Ovarian dysfunction
0.000 0.828 0.172
C43.7 Malignant melanoma of lower limb, including hip
0.170 0.830 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.838 0.162
E21.2 Other hyperparathyroidism
0.000 0.841 0.159
E24 Cushing's syndrome
0.000 0.841 0.159
E20 Hypoparathyroidism
0.000 0.843 0.157
E21.0 Primary hyperparathyroidism
0.000 0.848 0.152
E28.3 Primary ovarian failure
0.000 0.850 0.150
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.851 0.149
E29 Testicular dysfunction
0.000 0.858 0.141
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.861 0.138
E22 Hyperfunction of pituitary gland
0.000 0.861 0.139
L43 Lichen planus
0.000 0.863 0.137
E25.9 Adrenogenital disorder, unspecified
0.000 0.869 0.131
E25.8 Other adrenogenital disorders
0.000 0.869 0.131
E23 Hypofunction and other disorders of pituitary gland
0.000 0.870 0.130
C44.4 Skin of scalp and neck
0.127 0.873 0.000
G12.2 Motor neuron disease
0.000 0.873 0.127
E26.0 Primary hyperaldosteronism
0.000 0.873 0.127
E26.9 Hyperaldosteronism, unspecified
0.000 0.874 0.126
E26.8 Other hyperaldosteronism
0.000 0.874 0.126
E26.1 Secondary hyperaldosteronism
0.000 0.874 0.126
E30.9 Disorder of puberty, unspecified
0.000 0.874 0.126
E30.8 Other disorders of puberty
0.000 0.874 0.126
E30.1 Precocious puberty
0.000 0.874 0.126
E30.0 Delayed puberty
0.000 0.874 0.126
E31.9 Polyglandular dysfunction, unspecified
0.000 0.874 0.126
E31.8 Other polyglandular dysfunction
0.000 0.874 0.126
E31.1 Polyglandular hyperfunction
0.000 0.874 0.126
E31.0 Autoimmune polyglandular failure
0.000 0.874 0.126
E32.9 Disease of thymus, unspecified
0.000 0.874 0.126
E32.8 Other diseases of thymus
0.000 0.874 0.126
E32.1 Abscess of thymus
0.000 0.874 0.126
E32.0 Persistent hyperplasia of thymus
0.000 0.874 0.126
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.874 0.126
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.874 0.126
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.874 0.126
E28.9 Ovarian dysfunction, unspecified
0.000 0.876 0.124
E28.8 Other ovarian dysfunction
0.000 0.876 0.124
E28.1 Androgen excess
0.000 0.876 0.124
E28.0 Oestrogen excess
0.000 0.876 0.124
E04.1 Non-toxic single thyroid nodule
0.000 0.881 0.119
E22.0 Acromegaly and pituitary gigantism
0.000 0.886 0.114
E24.8 Other Cushing's syndrome
0.000 0.886 0.114
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.886 0.114
E24.3 Ectopic ACTH syndrome
0.000 0.886 0.114
E24.1 Nelson's syndrome
0.000 0.886 0.114
E04.2 Non-toxic multinodular goitre
0.000 0.886 0.114
E20.8 Other hypoparathyroidism
0.000 0.887 0.113
E20.1 Pseudohypoparathyroidism
0.000 0.887 0.113
E20.0 Idiopathic hypoparathyroidism
0.000 0.887 0.113
G12 Spinal muscular atrophy and related syndromes
0.000 0.888 0.112
L43.8 Other lichen planus
0.000 0.888 0.112
E24.9 Cushing's syndrome, unspecified
0.000 0.888 0.112
E24.2 Drug-induced Cushing's syndrome
0.000 0.891 0.109
E24.0 Pituitary-dependent Cushing's disease
0.000 0.894 0.106
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.898 0.102
E29.9 Testicular dysfunction, unspecified
0.000 0.898 0.102
E29.8 Other testicular dysfunction
0.000 0.898 0.102
E29.0 Testicular hyperfunction
0.000 0.898 0.102
G11 Hereditary ataxia
0.000 0.899 0.101
E34 Other endocrine disorders
0.000 0.899 0.100
E23.0 Hypopituitarism
0.000 0.900 0.100
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.900 0.099
E22.8 Other hyperfunction of pituitary gland
0.000 0.900 0.099
L43.3 Subacute (active) lichen planus
0.000 0.901 0.098
L43.2 Lichenoid drug reaction
0.000 0.901 0.098
L43.1 Bullous lichen planus
0.000 0.901 0.098
L43.0 Hypertrophic lichen planus
0.000 0.901 0.098
G11.9 Hereditary ataxia, unspecified
0.000 0.902 0.098
E04.9 Non-toxic goitre, unspecified
0.000 0.903 0.097
E20.9 Hypoparathyroidism, unspecified
0.000 0.906 0.094
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.906 0.094
E23.1 Drug-induced hypopituitarism
0.000 0.906 0.094
E70-E90 Metabolic disorders
0.000 0.909 0.091
G11.4 Hereditary spastic paraplegia
0.000 0.912 0.088
E23.7 Disorder of pituitary gland, unspecified
0.000 0.914 0.086
E83 Disorders of mineral metabolism
0.000 0.914 0.086
E23.2 Diabetes insipidus
0.000 0.915 0.085
E83.3 Disorders of phosphorus metabolism
0.000 0.917 0.083
E27 Other disorders of adrenal gland
0.000 0.919 0.081
G12.9 Spinal muscular atrophy, unspecified
0.000 0.919 0.081
G12.8 Other spinal muscular atrophies and related syndromes
0.000 0.919 0.081
G12.1 Other inherited spinal muscular atrophy
0.000 0.919 0.081
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.000 0.919 0.081
G10 Huntington's disease
0.000 0.922 0.078
E22.1 Hyperprolactinaemia
0.000 0.923 0.076
G14 Postpolio syndrome
0.000 0.925 0.075
E83.1 Disorders of iron metabolism
0.000 0.926 0.074
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.000 0.926 0.073
E79 Disorders of purine and pyrimidine metabolism
0.000 0.927 0.073
G11.8 Other hereditary ataxias
0.000 0.927 0.073
G11.3 Cerebellar ataxia with defective DNA repair
0.000 0.927 0.073
G11.2 Late-onset cerebellar ataxia
0.000 0.927 0.073
G11.1 Early-onset cerebellar ataxia
0.000 0.927 0.073
G11.0 Congenital nonprogressive ataxia
0.000 0.927 0.073
E34.5 Androgen resistance syndrome
0.000 0.928 0.072
E34.4 Constitutional tall stature
0.000 0.928 0.072
E34.3 Short stature, not elsewhere classified
0.000 0.928 0.072
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.928 0.072
E34.1 Other hypersecretion of intestinal hormones
0.000 0.928 0.072
E83.5 Disorders of calcium metabolism
0.000 0.928 0.072
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.932 0.067
E29.1 Testicular hypofunction
0.000 0.932 0.067
E84 Cystic fibrosis
0.000 0.935 0.065
E77 Disorders of glycoprotein metabolism
0.000 0.935 0.065
E76 Disorders of glycosaminoglycan metabolism
0.000 0.935 0.065
E72 Other disorders of amino-acid metabolism
0.000 0.935 0.065
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.935 0.065
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.935 0.065
E55.9 Vitamin D deficiency, unspecified
0.001 0.935 0.064
E23.6 Other disorders of pituitary gland
0.000 0.936 0.064
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.936 0.064
E88 Other metabolic disorders
0.000 0.938 0.062
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.938 0.062
E83.8 Other disorders of mineral metabolism
0.000 0.938 0.062
E83.2 Disorders of zinc metabolism
0.000 0.938 0.062
E83.0 Disorders of copper metabolism
0.000 0.938 0.062
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.938 0.061
E74 Other disorders of carbohydrate metabolism
0.000 0.939 0.061
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.940 0.060
E70 Disorders of aromatic amino-acid metabolism
0.000 0.940 0.060
E34.9 Endocrine disorder, unspecified
0.000 0.941 0.059
E34.8 Other specified endocrine disorders
0.000 0.941 0.058
E28.2 Polycystic ovarian syndrome
0.000 0.942 0.058
E27.5 Adrenomedullary hyperfunction
0.000 0.942 0.058
E27.0 Other adrenocortical overactivity
0.000 0.942 0.058
E27.9 Disorder of adrenal gland, unspecified
0.000 0.942 0.058
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.945 0.055
E73 Lactose intolerance
0.000 0.945 0.054
E34.0 Carcinoid syndrome
0.001 0.947 0.053
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere
0.000 0.947 0.053
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema
0.000 0.947 0.053
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease
0.000 0.947 0.053
G13.0 Paraneoplastic neuromyopathy and neuropathy
0.000 0.947 0.053
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.947 0.053
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.947 0.052
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.947 0.052
E79.1 Lesch-Nyhan syndrome
0.000 0.947 0.052
E88.2 Lipomatosis, not elsewhere classified
0.000 0.948 0.052
E78.2 Mixed hyperlipidaemia
0.000 0.948 0.052
E75.5 Other lipid storage disorders
0.000 0.949 0.051
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.949 0.050
E27.1 Primary adrenocortical insufficiency
0.000 0.950 0.050
E85 Amyloidosis
0.000 0.950 0.050
E75.6 Lipid storage disorder, unspecified
0.000 0.951 0.048
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.951 0.048
E75.3 Sphingolipidosis, unspecified
0.000 0.951 0.048
E75.1 Other gangliosidosis
0.000 0.951 0.048
E75.0 GM2 gangliosidosis
0.000 0.951 0.048
E75.2 Other sphingolipidosis
0.000 0.952 0.048
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.952 0.048
E89.2 Postprocedural hypoparathyroidism
0.000 0.953 0.047
E71.3 Disorders of fatty-acid metabolism
0.000 0.953 0.047
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.953 0.047
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.953 0.047
E71.0 Maple-syrup-urine disease
0.000 0.953 0.047
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.953 0.047
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.953 0.047
E72.5 Disorders of glycine metabolism
0.000 0.953 0.047
E72.4 Disorders of ornithine metabolism
0.000 0.953 0.047
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.953 0.047
E72.2 Disorders of urea cycle metabolism
0.000 0.953 0.047
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.953 0.047
E72.0 Disorders of amino-acid transport
0.000 0.953 0.047
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.953 0.047
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.953 0.047
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.953 0.047
E76.2 Other mucopolysaccharidoses
0.000 0.953 0.047
E76.1 Mucopolysaccharidosis, type II
0.000 0.953 0.047
E76.0 Mucopolysaccharidosis, type I
0.000 0.953 0.047
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.953 0.047
E77.8 Other disorders of glycoprotein metabolism
0.000 0.953 0.047
E77.1 Defects in glycoprotein degradation
0.000 0.953 0.047
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.953 0.047
E84.9 Cystic fibrosis, unspecified
0.000 0.953 0.047
E84.8 Cystic fibrosis with other manifestations
0.000 0.953 0.047
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.953 0.047
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.953 0.047
E88.8 Other specified metabolic disorders
0.000 0.955 0.045
E78.4 Other hyperlipidaemia
0.000 0.955 0.045
E88.9 Metabolic disorder, unspecified
0.000 0.955 0.044
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.956 0.044
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.956 0.044
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.956 0.044
E74.2 Disorders of galactose metabolism
0.000 0.956 0.044
E74.1 Disorders of fructose metabolism
0.000 0.956 0.044
E74.0 Glycogen storage disease
0.000 0.956 0.044
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.957 0.043
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.957 0.043
E70.2 Disorders of tyrosine metabolism
0.000 0.957 0.043
E70.1 Other hyperphenylalaninaemias
0.000 0.957 0.043
E70.0 Classical phenylketonuria
0.000 0.957 0.043
E78.8 Other disorders of lipoprotein metabolism
0.000 0.958 0.042
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.960 0.040
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.960 0.039
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.960 0.039
E89.5 Postprocedural testicular hypofunction
0.000 0.960 0.039
E89.1 Postprocedural hypoinsulinaemia
0.000 0.960 0.039
E27.2 Addisonian crisis
0.000 0.961 0.039
E73.8 Other lactose intolerance
0.000 0.961 0.039
E73.1 Secondary lactase deficiency
0.000 0.961 0.039
E73.0 Congenital lactase deficiency
0.000 0.961 0.039
E88.3 Tumour lysis syndrome
0.000 0.961 0.039
Z95.0 Presence of cardiac pacemaker
0.000 0.961 0.039
E78.1 Pure hyperglyceridaemia
0.000 0.962 0.038
E78.3 Hyperchylomicronaemia
0.000 0.962 0.038
E70.3 Albinism
0.000 0.962 0.037
E89.0 Postprocedural hypothyroidism
0.000 0.963 0.037
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.964 0.036
E85.8 Other amyloidosis
0.000 0.964 0.036
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.964 0.036
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.964 0.036
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.964 0.036
E78.6 Lipoprotein deficiency
0.000 0.964 0.036
E27.8 Other specified disorders of adrenal gland
0.000 0.966 0.034
E85.4 Organ-limited amyloidosis
0.000 0.966 0.034
E85.9 Amyloidosis, unspecified
0.000 0.967 0.033
E89.3 Postprocedural hypopituitarism
0.000 0.968 0.032
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.968 0.032
E89.4 Postprocedural ovarian failure
0.000 0.970 0.030
E85.3 Secondary systemic amyloidosis
0.000 0.971 0.029
E73.9 Lactose intolerance, unspecified
0.000 0.971 0.028
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.973 0.027
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.980 0.019
E80.5 Crigler-Najjar syndrome
0.000 0.980 0.019
E80.3 Defects of catalase and peroxydase
0.000 0.980 0.019
E80.0 Hereditary erythropoietic porphyria
0.000 0.980 0.019
E80.2 Other porphyria
0.000 0.983 0.017
E80.1 Porphyria cutanea tarda
0.000 0.983 0.017
E80.6 Other disorders of bilirubin metabolism
0.000 0.984 0.015
L40-L45 Papulosquamous disorders
0.000 0.985 0.015
E86 Volume depletion
0.000 0.986 0.014
E83.4 Disorders of magnesium metabolism
0.000 0.986 0.013
K50.9 Crohn's disease, unspecified
0.000 0.986 0.014
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.986 0.013
D23.3 Skin of other and unspecified parts of face
0.000 0.989 0.011
Z45.0 Adjustment and management of cardiac pacemaker
0.000 0.989 0.011
L41 Parapsoriasis
0.000 0.989 0.011
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.989 0.011
K50 Crohn's disease [regional enteritis]
0.000 0.989 0.011
E11 Non-insulin-dependent diabetes mellitus
0.000 0.989 0.011
K50.8 Other Crohn's disease
0.000 0.990 0.010
L03.0 Cellulitis of finger and toe
0.000 0.990 0.010
L44 Other papulosquamous disorders
0.000 0.990 0.009
E11.0 With coma
0.000 0.991 0.009
E80.4 Gilbert's syndrome
0.000 0.991 0.009
E78.5 Hyperlipidaemia, unspecified
0.000 0.991 0.009
K50.0 Crohn's disease of small intestine
0.000 0.991 0.009
L42 Pityriasis rosea
0.000 0.992 0.008
L41.9 Parapsoriasis, unspecified
0.000 0.992 0.008
L41.8 Other parapsoriasis
0.000 0.992 0.008
L41.5 Retiform parapsoriasis
0.000 0.992 0.008
L41.4 Large plaque parapsoriasis
0.000 0.992 0.008
L41.3 Small plaque parapsoriasis
0.000 0.992 0.008
L41.2 Lymphomatoid papulosis
0.000 0.992 0.008
L41.1 Pityriasis lichenoides chronica
0.000 0.992 0.008
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.992 0.008
E11.7 With multiple complications
0.000 0.992 0.008
E11.8 With unspecified complications
0.000 0.993 0.007
L44.9 Papulosquamous disorder, unspecified
0.000 0.993 0.007
L44.8 Other specified papulosquamous disorders
0.000 0.993 0.007
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.993 0.007
L44.3 Lichen ruber moniliformis
0.000 0.993 0.007
L44.2 Lichen striatus
0.000 0.993 0.007
L44.1 Lichen nitidus
0.000 0.993 0.007
K52.1 Toxic gastro-enteritis and colitis
0.000 0.993 0.007
R16.1 Splenomegaly, not elsewhere classified
0.000 0.993 0.007
E11.2 With renal complications
0.000 0.993 0.007
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.994 0.006
L44.0 Pityriasis rubra pilaris
0.000 0.994 0.006
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.000 0.994 0.006
E66.9 Obesity, unspecified
0.000 0.994 0.006
M79.67 Pain in limb (Ankle and foot)
0.000 0.994 0.006
E11.6 With other specified complications
0.000 0.994 0.006
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.006 0.994 0.000
I89.0 Lymphoedema, not elsewhere classified
0.000 0.994 0.006
G03 Meningitis due to other and unspecified causes
0.000 0.994 0.005
G09 Sequelae of inflammatory diseases of central nervous system
0.000 0.995 0.005
C32.1 Supraglottis
0.005 0.995 0.000
G00 Bacterial meningitis, not elsewhere classified
0.000 0.995 0.005
K50-K52 Noninfective enteritis and colitis
0.000 0.995 0.005
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified
0.000 0.995 0.005
G04 Encephalitis, myelitis and encephalomyelitis
0.000 0.995 0.005
G03.9 Meningitis, unspecified
0.000 0.995 0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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