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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9366816
log Bayes Factor = 14.1849
Chromosome 6   position 33,104,175  (GRCh37) Explore rs9366816 on Ensembl!
Variant rs9366816 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.002 0.998
E00-E07 Disorders of thyroid gland
0.000 0.003 0.997
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.003 0.997
E03 Other hypothyroidism
0.000 0.004 0.996
E03.9 Hypothyroidism, unspecified
0.000 0.004 0.996
E10.1 With ketoacidosis
0.000 0.005 0.995
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.040 0.960
E04 Other non-toxic goitre
0.000 0.046 0.954
E06 Thyroiditis
0.000 0.048 0.952
E16 Other disorders of pancreatic internal secretion
0.000 0.066 0.934
E10.2 With renal complications
0.000 0.074 0.926
E16.2 Hypoglycaemia, unspecified
0.000 0.079 0.921
E10.5 With peripheral circulatory complications
0.000 0.080 0.920
E10.4 With neurological complications
0.000 0.080 0.920
E06.3 Autoimmune thyroiditis
0.000 0.093 0.907
E04.1 Non-toxic single thyroid nodule
0.000 0.100 0.900
E11 Non-insulin-dependent diabetes mellitus
0.000 0.132 0.868
E50-E64 Other nutritional deficiencies
0.000 0.144 0.856
E04.2 Non-toxic multinodular goitre
0.000 0.144 0.856
E10.6 With other specified complications
0.000 0.189 0.811
E11.4 With neurological complications
0.000 0.194 0.806
E11.3 With ophthalmic complications
0.000 0.203 0.797
E53 Deficiency of other B group vitamins
0.000 0.212 0.788
E10.0 With coma
0.000 0.235 0.765
E06.9 Thyroiditis, unspecified
0.000 0.243 0.757
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.244 0.756
E53.8 Deficiency of other specified B group vitamins
0.000 0.244 0.756
E11.1 With ketoacidosis
0.000 0.248 0.752
E10.8 With unspecified complications
0.000 0.258 0.742
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.275 0.725
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.285 0.715
E00 Congenital iodine-deficiency syndrome
0.000 0.285 0.715
E03.5 Myxoedema coma
0.000 0.286 0.714
E03.4 Atrophy of thyroid (acquired)
0.000 0.286 0.714
E03.3 Postinfectious hypothyroidism
0.000 0.286 0.714
E03.1 Congenital hypothyroidism without goitre
0.000 0.286 0.714
E04.0 Non-toxic diffuse goitre
0.000 0.302 0.698
E20-E35 Disorders of other endocrine glands
0.000 0.303 0.697
E15 Nondiabetic hypoglycaemic coma
0.000 0.311 0.689
E04.8 Other specified non-toxic goitre
0.000 0.316 0.684
E06.5 Other chronic thyroiditis
0.000 0.318 0.682
E06.4 Drug-induced thyroiditis
0.000 0.318 0.682
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.318 0.682
E06.1 Subacute thyroiditis
0.000 0.318 0.682
E06.0 Acute thyroiditis
0.000 0.318 0.682
E11.2 With renal complications
0.000 0.322 0.678
E27 Other disorders of adrenal gland
0.000 0.328 0.672
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.330 0.670
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.330 0.670
E16.4 Abnormal secretion of gastrin
0.000 0.330 0.670
E16.3 Increased secretion of glucagon
0.000 0.330 0.670
E55 Vitamin D deficiency
0.000 0.335 0.665
E27.1 Primary adrenocortical insufficiency
0.000 0.338 0.662
E11.6 With other specified complications
0.000 0.364 0.636
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.365 0.635
E20 Hypoparathyroidism
0.000 0.366 0.634
E16.1 Other hypoglycaemia
0.000 0.370 0.630
E11.0 With coma
0.000 0.371 0.629
E14 Unspecified diabetes mellitus
0.000 0.376 0.624
E11.7 With multiple complications
0.000 0.378 0.622
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.386 0.614
E63 Other nutritional deficiencies
0.000 0.386 0.614
E56 Other vitamin deficiencies
0.000 0.386 0.614
E50 Vitamin A deficiency
0.000 0.386 0.614
E60 Dietary zinc deficiency
0.000 0.386 0.614
E59 Dietary selenium deficiency
0.000 0.386 0.614
E58 Dietary calcium deficiency
0.000 0.386 0.614
E54 Ascorbic acid deficiency
0.000 0.386 0.614
E52 Niacin deficiency [pellagra]
0.000 0.386 0.614
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.387 0.613
E51 Thiamine deficiency
0.000 0.397 0.603
E20.9 Hypoparathyroidism, unspecified
0.000 0.410 0.590
E53.1 Pyridoxine deficiency
0.000 0.435 0.565
E53.0 Riboflavin deficiency
0.000 0.435 0.565
K90.0 Coeliac disease
0.000 0.448 0.552
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.454 0.546
E14.3 With ophthalmic complications
0.000 0.464 0.536
K91.4 Colostomy and enterostomy malfunction
0.000 0.470 0.530
E13 Other specified diabetes mellitus
0.000 0.473 0.527
E55.9 Vitamin D deficiency, unspecified
0.000 0.473 0.527
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.485 0.515
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
E40-E46 Malnutrition
0.001 0.491 0.508
K90 Intestinal malabsorption
0.000 0.492 0.508
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.500 0.499
E32 Diseases of thymus
0.000 0.500 0.499
E31 Polyglandular dysfunction
0.000 0.500 0.499
E30 Disorders of puberty, not elsewhere classified
0.000 0.500 0.499
E25 Adrenogenital disorders
0.000 0.500 0.499
E27.2 Addisonian crisis
0.000 0.501 0.499
E04.9 Non-toxic goitre, unspecified
0.000 0.502 0.498
K90-K93 Other diseases of the digestive system
0.000 0.503 0.497
E22 Hyperfunction of pituitary gland
0.000 0.506 0.494
E27.5 Adrenomedullary hyperfunction
0.000 0.518 0.482
E27.0 Other adrenocortical overactivity
0.000 0.518 0.482
E27.9 Disorder of adrenal gland, unspecified
0.000 0.519 0.481
E55.0 Rickets, active
0.000 0.523 0.476
E11.8 With unspecified complications
0.000 0.525 0.475
E26 Hyperaldosteronism
0.000 0.529 0.471
E03.8 Other specified hypothyroidism
0.000 0.531 0.468
E53.9 Vitamin B deficiency, unspecified
0.000 0.545 0.455
E20.8 Other hypoparathyroidism
0.000 0.545 0.455
E20.1 Pseudohypoparathyroidism
0.000 0.545 0.455
E20.0 Idiopathic hypoparathyroidism
0.000 0.545 0.455
E14.1 With ketoacidosis
0.000 0.546 0.454
E07 Other disorders of thyroid
0.000 0.550 0.450
E14.7 With multiple complications
0.000 0.552 0.447
E14.6 With other specified complications
0.000 0.552 0.447
E14.2 Withrenal complications
0.000 0.552 0.447
E14.0 With coma
0.000 0.552 0.447
E14.8 With unspecified complications
0.000 0.557 0.443
E28 Ovarian dysfunction
0.000 0.558 0.442
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.559 0.441
E50.9 Vitamin A deficiency, unspecified
0.000 0.560 0.440
E50.8 Other manifestations of vitamin A deficiency
0.000 0.560 0.440
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.560 0.440
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.560 0.440
E50.5 Vitamin A deficiency with night blindness
0.000 0.560 0.440
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.560 0.440
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.560 0.440
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.560 0.440
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.560 0.440
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.560 0.440
E56.9 Vitamin deficiency, unspecified
0.000 0.560 0.440
E56.8 Deficiency of other vitamins
0.000 0.560 0.440
E56.1 Deficiency of vitamin K
0.000 0.560 0.440
E56.0 Deficiency of vitamin E
0.000 0.560 0.440
E63.9 Nutritional deficiency, unspecified
0.000 0.560 0.440
E63.8 Other specified nutritional deficiencies
0.000 0.560 0.440
E63.1 Imbalance of constituents of food intake
0.000 0.560 0.440
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.560 0.440
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.560 0.440
E64.8 Sequelae of other nutritional deficiencies
0.000 0.560 0.440
E64.3 Sequelae of rickets
0.000 0.560 0.440
E64.2 Sequelae of vitamin C deficiency
0.000 0.560 0.440
E64.1 Sequelae of vitamin A deficiency
0.000 0.560 0.440
E64.0 Sequelae of protein-energy malnutrition
0.000 0.560 0.440
E14.5 With peripheral circulatory complications
0.000 0.567 0.433
E51.9 Thiamine deficiency, unspecified
0.000 0.567 0.432
E51.8 Other manifestations of thiamine deficiency
0.000 0.567 0.432
E51.1 Beriberi
0.000 0.567 0.432
E34 Other endocrine disorders
0.000 0.575 0.425
E51.2 Wernicke's encephalopathy
0.000 0.578 0.422
E29 Testicular dysfunction
0.000 0.579 0.421
E61 Deficiency of other nutrient elements
0.000 0.581 0.419
E65-E68 Obesity and other hyperalimentation
0.000 0.590 0.410
K91.3 Postoperative intestinal obstruction
0.000 0.593 0.407
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.602 0.398
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.603 0.397
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.606 0.394
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.618 0.382
E13.8 With unspecified complications
0.000 0.622 0.378
E13.7 With multiple complications
0.000 0.622 0.378
E13.6 With other specified complications
0.000 0.622 0.378
E13.5 With peripheral circulatory complications
0.000 0.622 0.378
E13.4 With neurological complications
0.000 0.622 0.378
E13.3 With ophthalmic complications
0.000 0.622 0.378
E13.2 With renal complications
0.000 0.622 0.378
E13.1 With ketoacidosis
0.000 0.622 0.378
E13.0 With coma
0.000 0.622 0.378
K90.8 Other intestinal malabsorption
0.000 0.625 0.375
K91.1 Postgastric surgery syndromes
0.000 0.627 0.372
K91.5 Postcholecystectomy syndrome
0.000 0.631 0.369
E44 Protein-energy malnutrition of moderate and mild degree
0.001 0.635 0.364
E45 Retarded development following protein-energy malnutrition
0.001 0.635 0.364
E43 Unspecified severe protein-energy malnutrition
0.001 0.635 0.364
E42 Marasmic kwashiorkor
0.001 0.635 0.364
E41 Nutritional marasmus
0.001 0.635 0.364
E40 Kwashiorkor
0.001 0.635 0.364
K90.3 Pancreatic steatorrhoea
0.000 0.636 0.364
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.636 0.364
K90.1 Tropical sprue
0.000 0.636 0.364
E14.4 With neurological complications
0.000 0.641 0.359
E25.9 Adrenogenital disorder, unspecified
0.000 0.642 0.358
E25.8 Other adrenogenital disorders
0.000 0.642 0.358
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.642 0.358
E30.9 Disorder of puberty, unspecified
0.000 0.642 0.358
E30.8 Other disorders of puberty
0.000 0.642 0.358
E30.1 Precocious puberty
0.000 0.642 0.358
E30.0 Delayed puberty
0.000 0.642 0.358
E31.9 Polyglandular dysfunction, unspecified
0.000 0.642 0.358
E31.8 Other polyglandular dysfunction
0.000 0.642 0.358
E31.1 Polyglandular hyperfunction
0.000 0.642 0.358
E31.0 Autoimmune polyglandular failure
0.000 0.642 0.358
E32.9 Disease of thymus, unspecified
0.000 0.642 0.358
E32.8 Other diseases of thymus
0.000 0.642 0.358
E32.1 Abscess of thymus
0.000 0.642 0.358
E32.0 Persistent hyperplasia of thymus
0.000 0.642 0.358
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.642 0.358
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.642 0.358
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.642 0.358
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.643 0.356
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.646 0.354
E22.8 Other hyperfunction of pituitary gland
0.000 0.646 0.354
E28.3 Primary ovarian failure
0.000 0.649 0.350
E26.0 Primary hyperaldosteronism
0.000 0.650 0.350
E24 Cushing's syndrome
0.000 0.655 0.345
E27.8 Other specified disorders of adrenal gland
0.000 0.661 0.339
E26.8 Other hyperaldosteronism
0.000 0.662 0.337
E26.1 Secondary hyperaldosteronism
0.000 0.662 0.337
E22.1 Hyperprolactinaemia
0.000 0.664 0.336
K90.9 Intestinal malabsorption, unspecified
0.000 0.668 0.332
E07.1 Dyshormogenetic goitre
0.000 0.677 0.323
E07.0 Hypersecretion of calcitonin
0.000 0.677 0.323
E28.9 Ovarian dysfunction, unspecified
0.000 0.683 0.317
E28.8 Other ovarian dysfunction
0.000 0.683 0.317
E28.1 Androgen excess
0.000 0.683 0.317
E28.0 Oestrogen excess
0.000 0.683 0.317
E22.0 Acromegaly and pituitary gigantism
0.000 0.686 0.314
E34.5 Androgen resistance syndrome
0.000 0.695 0.305
E34.4 Constitutional tall stature
0.000 0.695 0.305
E34.3 Short stature, not elsewhere classified
0.000 0.695 0.305
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.695 0.305
E34.1 Other hypersecretion of intestinal hormones
0.000 0.695 0.305
E29.9 Testicular dysfunction, unspecified
0.000 0.698 0.302
E29.8 Other testicular dysfunction
0.000 0.698 0.302
E29.0 Testicular hyperfunction
0.000 0.698 0.302
E61.9 Deficiency of nutrient element, unspecified
0.000 0.699 0.300
E61.8 Deficiency of other specified nutrient elements
0.000 0.699 0.300
E61.7 Deficiency of multiple nutrient elements
0.000 0.699 0.300
E61.6 Vanadium deficiency
0.000 0.699 0.300
E61.5 Molybdenum deficiency
0.000 0.699 0.300
E61.4 Chromium deficiency
0.000 0.699 0.300
E61.3 Manganese deficiency
0.000 0.699 0.300
E61.0 Copper deficiency
0.000 0.699 0.300
E34.9 Endocrine disorder, unspecified
0.000 0.700 0.300
E67 Other hyperalimentation
0.000 0.706 0.294
E68 Sequelae of hyperalimentation
0.000 0.706 0.294
E26.9 Hyperaldosteronism, unspecified
0.000 0.708 0.292
E23 Hypofunction and other disorders of pituitary gland
0.000 0.708 0.292
E14.9 Without complications
0.000 0.713 0.287
E07.8 Other specified disorders of thyroid
0.000 0.715 0.284
E34.0 Carcinoid syndrome
0.000 0.723 0.277
E34.8 Other specified endocrine disorders
0.000 0.726 0.274
E44.1 Mild protein-energy malnutrition
0.001 0.738 0.261
E44.0 Moderate protein-energy malnutrition
0.001 0.738 0.261
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.741 0.259
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.744 0.256
K93.1 Megacolon in Chagas' disease
0.000 0.744 0.256
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.744 0.256
E65 Localised adiposity
0.000 0.746 0.254
E61.2 Magnesium deficiency
0.000 0.748 0.252
E24.2 Drug-induced Cushing's syndrome
0.000 0.751 0.248
E24.8 Other Cushing's syndrome
0.000 0.752 0.247
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.752 0.247
E24.3 Ectopic ACTH syndrome
0.000 0.752 0.247
E24.1 Nelson's syndrome
0.000 0.752 0.247
E23.6 Other disorders of pituitary gland
0.000 0.775 0.225
E29.1 Testicular hypofunction
0.000 0.777 0.223
E23.7 Disorder of pituitary gland, unspecified
0.000 0.786 0.214
E67.8 Other specified hyperalimentation
0.000 0.789 0.211
E67.3 Hypervitaminosis D
0.000 0.789 0.211
E67.2 Megavitamin-B6 syndrome
0.000 0.789 0.211
E67.1 Hypercarotenaemia
0.000 0.789 0.211
E67.0 Hypervitaminosis A
0.000 0.789 0.211
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.790 0.209
E23.1 Drug-induced hypopituitarism
0.000 0.790 0.209
E61.1 Iron deficiency
0.000 0.803 0.197
E24.9 Cushing's syndrome, unspecified
0.000 0.804 0.196
E28.2 Polycystic ovarian syndrome
0.000 0.806 0.194
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.809 0.191
E13.9 Without complications
0.001 0.810 0.189
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.811 0.189
E05.5 Thyroid crisis or storm
0.000 0.814 0.186
E05.4 Thyrotoxicosis factitia
0.000 0.814 0.186
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.814 0.186
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.814 0.186
E24.0 Pituitary-dependent Cushing's disease
0.001 0.822 0.177
E05.8 Other thyrotoxicosis
0.000 0.825 0.175
E11.5 With peripheral circulatory complications
0.001 0.827 0.172
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.837 0.163
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.001 0.840 0.158
E46 Unspecified protein-energy malnutrition
0.001 0.841 0.158
E07.9 Disorder of thyroid, unspecified
0.000 0.852 0.148
E21.4 Other specified disorders of parathyroid gland
0.000 0.863 0.137
E21.2 Other hyperparathyroidism
0.000 0.863 0.137
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.867 0.133
E23.0 Hypopituitarism
0.000 0.869 0.131
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.883 0.117
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.886 0.114
E21.0 Primary hyperparathyroidism
0.000 0.887 0.113
M06.9 Rheumatoid arthritis, unspecified
0.000 0.889 0.111
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.895 0.105
E23.2 Diabetes insipidus
0.001 0.900 0.099
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.901 0.099
E66 Obesity
0.000 0.902 0.098
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.908 0.092
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.909 0.091
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.001 0.910 0.090
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.912 0.088
M35.0 Sicca syndrome [Sjogren]
0.000 0.913 0.087
M35 Other systemic involvement of connective tissue
0.000 0.917 0.083
E05.9 Thyrotoxicosis, unspecified
0.000 0.917 0.083
M35.3 Polymyalgia rheumatica
0.000 0.917 0.083
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.924 0.076
M35.1 Other overlap syndromes
0.000 0.925 0.074
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.927 0.073
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.928 0.072
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.930 0.070
E66.1 Drug-induced obesity
0.000 0.930 0.070
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.931 0.069
E21.3 Hyperparathyroidism, unspecified
0.000 0.932 0.068
E66.0 Obesity due to excess calories
0.000 0.939 0.061
H36.0 Diabetic retinopathy
0.000 0.940 0.060
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.940 0.060
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.940 0.060
M35.5 Multifocal fibrosclerosis
0.000 0.940 0.060
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.940 0.060
M35.2 Behcet's disease
0.000 0.940 0.059
M35.7 Hypermobility syndrome
0.000 0.941 0.059
M35.8 Other specified systemic involvement of connective tissue
0.000 0.943 0.057
K92 Other diseases of digestive system
0.000 0.945 0.055
E66.8 Other obesity
0.000 0.953 0.047
K92.9 Disease of digestive system, unspecified
0.000 0.956 0.044
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.957 0.043
M06 Other rheumatoid arthritis
0.000 0.958 0.042
K92.8 Other specified diseases of digestive system
0.000 0.959 0.041
E70-E90 Metabolic disorders
0.000 0.966 0.034
M06.3 Rheumatoid nodule
0.000 0.967 0.033
M06.4 Inflammatory polyarthropathy
0.000 0.969 0.031
M06.8 Other specified rheumatoid arthritis
0.000 0.970 0.030
M06.2 Rheumatoid bursitis
0.000 0.970 0.030
M06.1 Adult-onset Still's disease
0.000 0.970 0.030
H36 Retinal disorders in diseases classified elsewhere
0.000 0.973 0.027
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.973 0.027
E83 Disorders of mineral metabolism
0.000 0.974 0.026
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.975 0.025
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.975 0.025
E79 Disorders of purine and pyrimidine metabolism
0.000 0.975 0.025
E77 Disorders of glycoprotein metabolism
0.000 0.976 0.024
E76 Disorders of glycosaminoglycan metabolism
0.000 0.976 0.024
E72 Other disorders of amino-acid metabolism
0.000 0.976 0.024
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.976 0.024
E70 Disorders of aromatic amino-acid metabolism
0.000 0.976 0.024
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.976 0.024
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.976 0.024
M06.34 Rheumatoid nodule (Hand)
0.000 0.976 0.024
E83.1 Disorders of iron metabolism
0.000 0.976 0.024
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.976 0.024
M06.38 Rheumatoid nodule (Other)
0.000 0.976 0.024
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.976 0.024
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.976 0.024
M06.33 Rheumatoid nodule (Forearm)
0.000 0.976 0.024
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.976 0.024
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.976 0.024
E74 Other disorders of carbohydrate metabolism
0.000 0.977 0.023
E84 Cystic fibrosis
0.000 0.977 0.023
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.977 0.023
E89.0 Postprocedural hypothyroidism
0.000 0.977 0.023
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.978 0.022
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.978 0.022
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.978 0.022
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.978 0.022
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.978 0.022
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.978 0.022
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.978 0.022
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.978 0.022
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.978 0.022
M06.18 Adult-onset Still's disease (Other)
0.000 0.978 0.022
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.978 0.022
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.978 0.022
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.978 0.022
M06.14 Adult-onset Still's disease (Hand)
0.000 0.978 0.022
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.978 0.022
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.978 0.022
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.978 0.022
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.978 0.022
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.978 0.022
M06.28 Rheumatoid bursitis (Other)
0.000 0.978 0.022
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.978 0.022
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.978 0.022
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.978 0.022
M06.24 Rheumatoid bursitis (Hand)
0.000 0.978 0.022
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.978 0.022
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.978 0.022
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.978 0.022
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.978 0.022
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.978 0.022
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.978 0.022
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.978 0.022
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.978 0.022
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.978 0.022
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.978 0.022
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.978 0.022
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.978 0.022
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.978 0.022
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.978 0.022
E83.4 Disorders of magnesium metabolism
0.000 0.978 0.022
E89.3 Postprocedural hypopituitarism
0.000 0.979 0.021
E89.2 Postprocedural hypoparathyroidism
0.000 0.979 0.021
E73 Lactose intolerance
0.000 0.979 0.021
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.979 0.020
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.980 0.020
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.980 0.019
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.981 0.019
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.981 0.019
E89.5 Postprocedural testicular hypofunction
0.000 0.981 0.019
E89.1 Postprocedural hypoinsulinaemia
0.000 0.981 0.019
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.981 0.019
E83.8 Other disorders of mineral metabolism
0.000 0.981 0.019
E83.2 Disorders of zinc metabolism
0.000 0.981 0.019
E83.0 Disorders of copper metabolism
0.000 0.981 0.019
E85 Amyloidosis
0.000 0.981 0.019
M06.0 Seronegative rheumatoid arthritis
0.000 0.981 0.019
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.982 0.018
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.982 0.018
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.982 0.018
E79.1 Lesch-Nyhan syndrome
0.000 0.982 0.018
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.982 0.017
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.982 0.017
E70.3 Albinism
0.000 0.982 0.017
E70.2 Disorders of tyrosine metabolism
0.000 0.982 0.017
E70.1 Other hyperphenylalaninaemias
0.000 0.982 0.017
E70.0 Classical phenylketonuria
0.000 0.982 0.017
E71.3 Disorders of fatty-acid metabolism
0.000 0.982 0.017
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.982 0.017
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.982 0.017
E71.0 Maple-syrup-urine disease
0.000 0.982 0.017
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.982 0.017
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.982 0.017
E72.5 Disorders of glycine metabolism
0.000 0.982 0.017
E72.4 Disorders of ornithine metabolism
0.000 0.982 0.017
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.982 0.017
E72.2 Disorders of urea cycle metabolism
0.000 0.982 0.017
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.982 0.017
E72.0 Disorders of amino-acid transport
0.000 0.982 0.017
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.982 0.017
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.982 0.017
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.982 0.017
E76.2 Other mucopolysaccharidoses
0.000 0.982 0.017
E76.1 Mucopolysaccharidosis, type II
0.000 0.982 0.017
E76.0 Mucopolysaccharidosis, type I
0.000 0.982 0.017
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.982 0.017
E77.8 Other disorders of glycoprotein metabolism
0.000 0.982 0.017
E77.1 Defects in glycoprotein degradation
0.000 0.982 0.017
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.982 0.017
E89.4 Postprocedural ovarian failure
0.000 0.983 0.017
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.983 0.017
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.983 0.017
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.983 0.017
E74.2 Disorders of galactose metabolism
0.000 0.983 0.017
E74.1 Disorders of fructose metabolism
0.000 0.983 0.017
E74.0 Glycogen storage disease
0.000 0.983 0.017
E84.8 Cystic fibrosis with other manifestations
0.000 0.983 0.017
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.983 0.017
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.983 0.017
E75.6 Lipid storage disorder, unspecified
0.000 0.983 0.016
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.983 0.016
E75.3 Sphingolipidosis, unspecified
0.000 0.983 0.016
E75.2 Other sphingolipidosis
0.000 0.983 0.016
E75.1 Other gangliosidosis
0.000 0.983 0.016
E75.0 GM2 gangliosidosis
0.000 0.983 0.016
E83.3 Disorders of phosphorus metabolism
0.000 0.984 0.016
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.984 0.016
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.984 0.016
E88 Other metabolic disorders
0.000 0.984 0.016
E84.9 Cystic fibrosis, unspecified
0.000 0.984 0.016
E75.5 Other lipid storage disorders
0.000 0.985 0.015
E73.8 Other lactose intolerance
0.000 0.985 0.015
E73.1 Secondary lactase deficiency
0.000 0.985 0.015
E73.0 Congenital lactase deficiency
0.000 0.985 0.015
E80.6 Other disorders of bilirubin metabolism
0.000 0.985 0.015
E11.9 Without complications
0.000 0.985 0.015
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.985 0.014
E80.5 Crigler-Najjar syndrome
0.000 0.985 0.014
E80.3 Defects of catalase and peroxydase
0.000 0.985 0.014
E80.2 Other porphyria
0.000 0.985 0.014
E80.0 Hereditary erythropoietic porphyria
0.000 0.985 0.014
Z87.8 Personal history of other specified conditions
0.000 0.986 0.014
E85.4 Organ-limited amyloidosis
0.000 0.986 0.014
E86 Volume depletion
0.000 0.986 0.014
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.986 0.014
E85.8 Other amyloidosis
0.000 0.986 0.014
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.986 0.014
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.986 0.014
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.986 0.014
E80.1 Porphyria cutanea tarda
0.000 0.986 0.014
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.986 0.013

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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