TreeWAS – Variant ID: rs9368606

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40 Psoriasis	0.995	0.005	0.000
L40.5 Arthropathic psoriasis	0.993	0.007	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.117	0.883
L40.0 Psoriasis vulgaris	0.798	0.202	0.000
L40.4 Guttate psoriasis	0.777	0.223	0.000
L40.1 Generalised pustular psoriasis	0.767	0.233	0.000
L40.3 Pustulosis palmaris et plantaris	0.713	0.286	0.000
L40.2 Acrodermatitis continua	0.713	0.286	0.000
K90 Intestinal malabsorption	0.000	0.362	0.638
L40.8 Other psoriasis	0.623	0.377	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.449	0.551
K90.8 Other intestinal malabsorption	0.000	0.520	0.480
K90.3 Pancreatic steatorrhoea	0.000	0.542	0.458
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.542	0.458
K90.1 Tropical sprue	0.000	0.542	0.458
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.549	0.450
E03 Other hypothyroidism	0.000	0.609	0.391
M47.82 Other spondylosis (Cervical region)	0.296	0.704	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.705	0.294
E03.5 Myxoedema coma	0.000	0.720	0.280
E03.4 Atrophy of thyroid (acquired)	0.000	0.720	0.280
E03.3 Postinfectious hypothyroidism	0.000	0.720	0.280
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.746	0.254
E83.1 Disorders of iron metabolism	0.000	0.746	0.254
E03.1 Congenital hypothyroidism without goitre	0.000	0.749	0.251
E03.8 Other specified hypothyroidism	0.000	0.772	0.228
M47.8 Other spondylosis	0.216	0.784	0.000
E00-E07 Disorders of thyroid gland	0.000	0.785	0.215
M35.0 Sicca syndrome [Sjogren]	0.000	0.807	0.193
M47.89 Other spondylosis (Site unspecified)	0.188	0.812	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.188	0.812	0.000
L40-L45 Papulosquamous disorders	0.176	0.824	0.000
E06 Thyroiditis	0.000	0.824	0.176
E83 Disorders of mineral metabolism	0.000	0.828	0.172
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.831	0.169
E07 Other disorders of thyroid	0.000	0.835	0.165
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.838	0.162
M47.85 Other spondylosis (Thoracolumbar region)	0.161	0.839	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.158	0.842	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.155	0.845	0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.155	0.845	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.845	0.155
E00 Congenital iodine-deficiency syndrome	0.000	0.845	0.155
E06.3 Autoimmune thyroiditis	0.000	0.847	0.153
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.850	0.150
M47.84 Other spondylosis (Thoracic region)	0.147	0.853	0.000
E83.4 Disorders of magnesium metabolism	0.000	0.860	0.140
E07.9 Disorder of thyroid, unspecified	0.000	0.864	0.136
M47.87 Other spondylosis (Lumbosacral region)	0.136	0.864	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.865	0.135
E83.5 Disorders of calcium metabolism	0.000	0.871	0.129
L44 Other papulosquamous disorders	0.126	0.873	0.000
L41 Parapsoriasis	0.126	0.873	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.126	0.873	0.000
E06.5 Other chronic thyroiditis	0.000	0.874	0.126
E06.4 Drug-induced thyroiditis	0.000	0.874	0.126
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.874	0.126
E06.1 Subacute thyroiditis	0.000	0.874	0.126
E06.0 Acute thyroiditis	0.000	0.874	0.126
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.877	0.123
E83.8 Other disorders of mineral metabolism	0.000	0.877	0.123
E83.2 Disorders of zinc metabolism	0.000	0.877	0.123
E83.0 Disorders of copper metabolism	0.000	0.877	0.123
E05.5 Thyroid crisis or storm	0.000	0.879	0.121
E05.4 Thyrotoxicosis factitia	0.000	0.879	0.121
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.879	0.121
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.879	0.121
E07.1 Dyshormogenetic goitre	0.000	0.881	0.118
E07.0 Hypersecretion of calcitonin	0.000	0.881	0.118
E06.9 Thyroiditis, unspecified	0.000	0.885	0.114
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.889	0.111
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.889	0.111
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.889	0.111
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.889	0.111
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.889	0.111
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.889	0.111
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.889	0.111
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.889	0.111
M47.86 Other spondylosis (Lumbar region)	0.110	0.890	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.893	0.107
E07.8 Other specified disorders of thyroid	0.000	0.893	0.106
E05.8 Other thyrotoxicosis	0.000	0.894	0.106
M47 Spondylosis	0.101	0.899	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.900	0.100
E27 Other disorders of adrenal gland	0.000	0.905	0.095
E27.1 Primary adrenocortical insufficiency	0.000	0.906	0.094
E70-E90 Metabolic disorders	0.000	0.906	0.094
L42 Pityriasis rosea	0.093	0.907	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.907	0.093
L41.9 Parapsoriasis, unspecified	0.091	0.909	0.000
L41.8 Other parapsoriasis	0.091	0.909	0.000
L41.5 Retiform parapsoriasis	0.091	0.909	0.000
L41.4 Large plaque parapsoriasis	0.091	0.909	0.000
L41.3 Small plaque parapsoriasis	0.091	0.909	0.000
L41.2 Lymphomatoid papulosis	0.091	0.909	0.000
L41.1 Pityriasis lichenoides chronica	0.091	0.909	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.091	0.909	0.000
L44.9 Papulosquamous disorder, unspecified	0.091	0.909	0.000
L44.8 Other specified papulosquamous disorders	0.091	0.909	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.091	0.909	0.000
L44.3 Lichen ruber moniliformis	0.091	0.909	0.000
L44.2 Lichen striatus	0.091	0.909	0.000
L44.1 Lichen nitidus	0.091	0.909	0.000
L44.0 Pityriasis rubra pilaris	0.091	0.909	0.000
M45-M49 Spondylopathies	0.089	0.911	0.000
M35 Other systemic involvement of connective tissue	0.000	0.912	0.088
M87 Osteonecrosis	0.087	0.913	0.000
M89 Other disorders of bone	0.086	0.914	0.000
M86-M90 Other osteopathies	0.086	0.914	0.000
M87.9 Osteonecrosis, unspecified	0.086	0.914	0.000
M45 Ankylosing spondylitis	0.085	0.915	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.918	0.082
E86 Volume depletion	0.000	0.918	0.082
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.080	0.920	0.000
E40-E46 Malnutrition	0.000	0.920	0.080
M89.9 Disorder of bone, unspecified	0.079	0.920	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.079	0.921	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.921	0.078
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.078	0.922	0.000
L43 Lichen planus	0.076	0.924	0.000
E27.2 Addisonian crisis	0.000	0.925	0.075
M89.94 Disorder of bone, unspecified (Hand)	0.073	0.927	0.000
E29 Testicular dysfunction	0.000	0.927	0.073
M47.0 Anterior spinal and vertebral artery compression syndromes	0.073	0.927	0.000
M87.2 Osteonecrosis due to previous trauma	0.072	0.927	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.071	0.929	0.000
M89.8 Other specified disorders of bone	0.071	0.929	0.000
E20 Hypoparathyroidism	0.000	0.929	0.071
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.071	0.929	0.000
M87.8 Other osteonecrosis	0.070	0.929	0.000
M89.5 Osteolysis	0.070	0.930	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.930	0.070
M89.0 Algoneurodystrophy	0.069	0.930	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.070	0.930	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.932	0.068
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.932	0.068
E27.0 Other adrenocortical overactivity	0.000	0.932	0.068
E74 Other disorders of carbohydrate metabolism	0.000	0.932	0.068
E77 Disorders of glycoprotein metabolism	0.000	0.932	0.068
E76 Disorders of glycosaminoglycan metabolism	0.000	0.932	0.068
E72 Other disorders of amino-acid metabolism	0.000	0.932	0.068
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.932	0.068
E70 Disorders of aromatic amino-acid metabolism	0.000	0.932	0.068
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.932	0.068
E34 Other endocrine disorders	0.000	0.932	0.068
M35.3 Polymyalgia rheumatica	0.000	0.932	0.068
E22 Hyperfunction of pituitary gland	0.000	0.932	0.068
M35.2 Behcet's disease	0.000	0.933	0.067
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.933	0.067
E32 Diseases of thymus	0.000	0.933	0.067
E31 Polyglandular dysfunction	0.000	0.933	0.067
E30 Disorders of puberty, not elsewhere classified	0.000	0.933	0.067
M89.3 Hypertrophy of bone	0.067	0.933	0.000
E84 Cystic fibrosis	0.000	0.933	0.067
M87.98 Osteonecrosis, unspecified (Other)	0.067	0.933	0.000
M86 Osteomyelitis	0.067	0.933	0.000
M49 Spondylopathies in diseases classified elsewhere	0.065	0.935	0.000
M60-M63 Disorders of muscles	0.065	0.935	0.000
E79 Disorders of purine and pyrimidine metabolism	0.000	0.935	0.065
E46 Unspecified protein-energy malnutrition	0.000	0.935	0.065
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.064	0.936	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.936	0.064
M35.8 Other specified systemic involvement of connective tissue	0.000	0.936	0.064
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.936	0.064
M35.5 Multifocal fibrosclerosis	0.000	0.936	0.064
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.936	0.064
E25 Adrenogenital disorders	0.000	0.936	0.063
M47.2 Other spondylosis with radiculopathy	0.064	0.936	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.937	0.063
M62 Other disorders of muscle	0.063	0.937	0.000
M87.3 Other secondary osteonecrosis	0.063	0.937	0.000
M87.1 Osteonecrosis due to drugs	0.063	0.937	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.063	0.937	0.000
E26 Hyperaldosteronism	0.000	0.938	0.062
E73 Lactose intolerance	0.000	0.938	0.062
M89.6 Osteopathy after poliomyelitis	0.062	0.938	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.062	0.938	0.000
M89.2 Other disorders of bone development and growth	0.062	0.938	0.000
M89.1 Epiphyseal arrest	0.062	0.938	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.062	0.938	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.062	0.938	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.062	0.938	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.062	0.938	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.062	0.938	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.938	0.061
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.061	0.939	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.061	0.939	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.061	0.939	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.061	0.939	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.061	0.939	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.061	0.939	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.061	0.939	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.061	0.939	0.000
E24 Cushing's syndrome	0.000	0.939	0.061
M89.81 Other specified disorders of bone (Shoulder region)	0.060	0.940	0.000
M35.1 Other overlap syndromes	0.000	0.940	0.060
M46 Other inflammatory spondylopathies	0.060	0.940	0.000
E28 Ovarian dysfunction	0.000	0.940	0.060
M45.X2 Ankylosing spondylitis (Cervical region)	0.060	0.940	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.059	0.940	0.000
M89.88 Other specified disorders of bone (Other)	0.059	0.941	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.059	0.941	0.000
M90 Osteopathies in diseases classified elsewhere	0.059	0.941	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.059	0.941	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.941	0.059
E50-E64 Other nutritional deficiencies	0.000	0.941	0.059
E29.1 Testicular hypofunction	0.000	0.941	0.059
I63.9 Cerebral infarction, unspecified	0.000	0.942	0.058
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.058	0.942	0.000
M00-M03 Infectious arthropathies	0.058	0.942	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.058	0.942	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.942	0.058
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.942	0.058
I63 Cerebral infarction	0.000	0.943	0.057
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.943	0.057
E45 Retarded development following protein-energy malnutrition	0.000	0.943	0.057
E43 Unspecified severe protein-energy malnutrition	0.000	0.943	0.057
E42 Marasmic kwashiorkor	0.000	0.943	0.057
E41 Nutritional marasmus	0.000	0.943	0.057
E40 Kwashiorkor	0.000	0.943	0.057
M89.99 Disorder of bone, unspecified (Site unspecified)	0.057	0.943	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.057	0.943	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.057	0.943	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.057	0.943	0.000
M47.1 Other spondylosis with myelopathy	0.057	0.943	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.944	0.056
M89.07 Algoneurodystrophy (Ankle and foot)	0.056	0.944	0.000
M89.03 Algoneurodystrophy (Forearm)	0.056	0.944	0.000
E20.9 Hypoparathyroidism, unspecified	0.000	0.944	0.056
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.055	0.945	0.000
M22.2 Patellofemoral disorders	0.000	0.945	0.055
E34.0 Carcinoid syndrome	0.000	0.945	0.055
M62.8 Other specified disorders of muscle	0.055	0.945	0.000
L43.3 Subacute (active) lichen planus	0.055	0.945	0.000
L43.2 Lichenoid drug reaction	0.055	0.945	0.000
L43.1 Bullous lichen planus	0.055	0.945	0.000
L43.0 Hypertrophic lichen planus	0.055	0.945	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.055	0.945	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.055	0.945	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.946	0.054
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.001	0.946	0.054
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.053	0.946	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.053	0.946	0.000
E85 Amyloidosis	0.000	0.947	0.053
M89.37 Hypertrophy of bone (Ankle and foot)	0.053	0.947	0.000
K90-K93 Other diseases of the digestive system	0.000	0.947	0.053
M40-M43 Deforming dorsopathies	0.053	0.947	0.000
E29.9 Testicular dysfunction, unspecified	0.000	0.947	0.053
E29.8 Other testicular dysfunction	0.000	0.947	0.053
E29.0 Testicular hyperfunction	0.000	0.947	0.053
M89.09 Algoneurodystrophy (Site unspecified)	0.053	0.947	0.000
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)	0.052	0.947	0.000
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)	0.052	0.947	0.000
M47.07 Anterior spinal and vertebral artery compression syndromes (Lumbosacral region)	0.052	0.947	0.000
M47.06 Anterior spinal and vertebral artery compression syndromes (Lumbar region)	0.052	0.947	0.000
M47.05 Anterior spinal and vertebral artery compression syndromes (Thoracolumbar region)	0.052	0.947	0.000
M47.04 Anterior spinal and vertebral artery compression syndromes (Thoracic region)	0.052	0.947	0.000
M47.03 Anterior spinal and vertebral artery compression syndromes (Cervicothoracic region)	0.052	0.947	0.000
M47.02 Anterior spinal and vertebral artery compression syndromes (Cervical region)	0.052	0.947	0.000
M47.01 Anterior spinal and vertebral artery compression syndromes (Occipito-atlanto-axial region)	0.052	0.947	0.000
M47.00 Anterior spinal and vertebral artery compression syndromes (Multiple sites in spine)	0.052	0.947	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.052	0.948	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.052	0.948	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.052	0.948	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.052	0.948	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.052	0.948	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.052	0.948	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.052	0.948	0.000
M86.9 Osteomyelitis, unspecified	0.051	0.949	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.051	0.949	0.000
M89.83 Other specified disorders of bone (Forearm)	0.051	0.949	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.051	0.949	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.051	0.949	0.000
E20.8 Other hypoparathyroidism	0.000	0.949	0.051
E20.1 Pseudohypoparathyroidism	0.000	0.949	0.051
E20.0 Idiopathic hypoparathyroidism	0.000	0.949	0.051
M89.84 Other specified disorders of bone (Hand)	0.051	0.949	0.000
M87.89 Other osteonecrosis (Site unspecified)	0.051	0.949	0.000
M87.88 Other osteonecrosis (Other)	0.051	0.949	0.000
M87.87 Other osteonecrosis (Ankle and foot)	0.051	0.949	0.000
M87.86 Other osteonecrosis (Lower leg)	0.051	0.949	0.000
M87.84 Other osteonecrosis (Hand)	0.051	0.949	0.000
M87.83 Other osteonecrosis (Forearm)	0.051	0.949	0.000
M87.82 Other osteonecrosis (Upper arm)	0.051	0.949	0.000
M87.81 Other osteonecrosis (Shoulder region)	0.051	0.949	0.000
M87.80 Other osteonecrosis (Multiple sites)	0.051	0.949	0.000
M89.59 Osteolysis (Site unspecified)	0.051	0.949	0.000
M89.58 Osteolysis (Other)	0.051	0.949	0.000
M89.57 Osteolysis (Ankle and foot)	0.051	0.949	0.000
M89.56 Osteolysis (Lower leg)	0.051	0.949	0.000
M89.54 Osteolysis (Hand)	0.051	0.949	0.000
M89.53 Osteolysis (Forearm)	0.051	0.949	0.000
M89.52 Osteolysis (Upper arm)	0.051	0.949	0.000
M89.51 Osteolysis (Shoulder region)	0.051	0.949	0.000
M89.50 Osteolysis (Multiple sites)	0.051	0.949	0.000
M62.0 Diastasis of muscle	0.050	0.949	0.000
M86.6 Other chronic osteomyelitis	0.050	0.949	0.000
M07.3 Other psoriatic arthropathies	0.050	0.950	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.950	0.050
M91-M94 Chondropathies	0.050	0.950	0.000
M89.08 Algoneurodystrophy (Other)	0.050	0.950	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.050	0.950	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.050	0.950	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.050	0.950	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.050	0.950	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.050	0.950	0.000
M46.2 Osteomyelitis of vertebra	0.050	0.950	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.050	0.950	0.000
M62.6 Muscle strain	0.049	0.951	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.049	0.951	0.000
M07 Psoriatic and enteropathic arthropathies	0.049	0.951	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.951	0.049
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.951	0.049
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.951	0.049
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.951	0.049
E74.2 Disorders of galactose metabolism	0.000	0.951	0.049
E74.1 Disorders of fructose metabolism	0.000	0.951	0.049
E74.0 Glycogen storage disease	0.000	0.951	0.049
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.951	0.049
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.951	0.049
E70.3 Albinism	0.000	0.951	0.049
E70.2 Disorders of tyrosine metabolism	0.000	0.951	0.049
E70.1 Other hyperphenylalaninaemias	0.000	0.951	0.049
E70.0 Classical phenylketonuria	0.000	0.951	0.049
E71.3 Disorders of fatty-acid metabolism	0.000	0.951	0.049
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.951	0.049
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.951	0.049
E71.0 Maple-syrup-urine disease	0.000	0.951	0.049
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.951	0.049
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.951	0.049
E72.5 Disorders of glycine metabolism	0.000	0.951	0.049
E72.4 Disorders of ornithine metabolism	0.000	0.951	0.049
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.951	0.049
E72.2 Disorders of urea cycle metabolism	0.000	0.951	0.049
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.951	0.049
E72.0 Disorders of amino-acid transport	0.000	0.951	0.049
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.951	0.049
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.951	0.049
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.951	0.049
E76.2 Other mucopolysaccharidoses	0.000	0.951	0.049
E76.1 Mucopolysaccharidosis, type II	0.000	0.951	0.049
E76.0 Mucopolysaccharidosis, type I	0.000	0.951	0.049
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.951	0.049
E77.8 Other disorders of glycoprotein metabolism	0.000	0.951	0.049
E77.1 Defects in glycoprotein degradation	0.000	0.951	0.049
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.951	0.049
E34.5 Androgen resistance syndrome	0.000	0.951	0.049
E34.4 Constitutional tall stature	0.000	0.951	0.049
E34.3 Short stature, not elsewhere classified	0.000	0.951	0.049
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.951	0.049
E34.1 Other hypersecretion of intestinal hormones	0.000	0.951	0.049
M89.38 Hypertrophy of bone (Other)	0.049	0.951	0.000
M05-M14 Inflammatory polyarthropathies	0.049	0.951	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.951	0.049
E22.8 Other hyperfunction of pituitary gland	0.000	0.951	0.049
E23.6 Other disorders of pituitary gland	0.000	0.951	0.049
E30.9 Disorder of puberty, unspecified	0.000	0.952	0.048
E30.8 Other disorders of puberty	0.000	0.952	0.048
E30.1 Precocious puberty	0.000	0.952	0.048
E30.0 Delayed puberty	0.000	0.952	0.048
E31.9 Polyglandular dysfunction, unspecified	0.000	0.952	0.048
E31.8 Other polyglandular dysfunction	0.000	0.952	0.048
E31.1 Polyglandular hyperfunction	0.000	0.952	0.048
E31.0 Autoimmune polyglandular failure	0.000	0.952	0.048
E32.9 Disease of thymus, unspecified	0.000	0.952	0.048
E32.8 Other diseases of thymus	0.000	0.952	0.048
E32.1 Abscess of thymus	0.000	0.952	0.048
E32.0 Persistent hyperplasia of thymus	0.000	0.952	0.048
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.952	0.048
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.952	0.048
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.952	0.048
M89.06 Algoneurodystrophy (Lower leg)	0.048	0.952	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.048	0.952	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.048	0.952	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.048	0.952	0.000
M89.34 Hypertrophy of bone (Hand)	0.048	0.952	0.000
M89.33 Hypertrophy of bone (Forearm)	0.048	0.952	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.048	0.952	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.048	0.952	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.048	0.952	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.048	0.952	0.000
E84.8 Cystic fibrosis with other manifestations	0.000	0.952	0.048
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.952	0.048
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.952	0.048
M86.5 Other chronic haematogenous osteomyelitis	0.048	0.952	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.048	0.952	0.000
M86.3 Chronic multifocal osteomyelitis	0.048	0.952	0.000
M86.2 Subacute osteomyelitis	0.048	0.952	0.000
M86.1 Other acute osteomyelitis	0.048	0.952	0.000
M86.0 Acute haematogenous osteomyelitis	0.048	0.952	0.000
M88 Paget's disease of bone [osteitis deformans]	0.047	0.952	0.001
E22.1 Hyperprolactinaemia	0.000	0.952	0.048
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.047	0.952	0.000
M02 Reactive arthropathies	0.047	0.952	0.000
M43 Other deforming dorsopathies	0.048	0.952	0.000
M22 Disorders of patella	0.000	0.953	0.047
M07.39 Other psoriatic arthropathies (Site unspecified)	0.047	0.953	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.047	0.953	0.000
E84.9 Cystic fibrosis, unspecified	0.000	0.953	0.047
M86.94 Osteomyelitis, unspecified (Hand)	0.047	0.953	0.000
M62.88 Other specified disorders of muscle (Other)	0.047	0.953	0.000
M49.8 Spondylopathy in other diseases classified elsewhere	0.047	0.953	0.000
M49.4 Neuropathic spondylopathy	0.047	0.953	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.047	0.953	0.000
M49.2 Enterobacterial spondylitis	0.047	0.953	0.000
M49.1 Brucella spondylitis	0.047	0.953	0.000
M49.0 Tuberculosis of spine	0.047	0.953	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.047	0.953	0.000
M61 Calcification and ossification of muscle	0.047	0.953	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.953	0.047
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.953	0.047
E79.1 Lesch-Nyhan syndrome	0.000	0.953	0.047
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.047	0.953	0.000
M99 Biomechanical lesions, not elsewhere classified	0.047	0.953	0.000
M86.8 Other osteomyelitis	0.047	0.953	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.047	0.953	0.000
E23.2 Diabetes insipidus	0.000	0.953	0.046
E34.9 Endocrine disorder, unspecified	0.000	0.954	0.046
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.954	0.046
E25.9 Adrenogenital disorder, unspecified	0.000	0.954	0.046
E25.8 Other adrenogenital disorders	0.000	0.954	0.046
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.046	0.954	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.046	0.954	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.046	0.954	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.046	0.954	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.046	0.954	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.046	0.954	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.046	0.954	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.954	0.046
E23.1 Drug-induced hypopituitarism	0.000	0.954	0.046
M62.9 Disorder of muscle, unspecified	0.045	0.954	0.000
M62.4 Contracture of muscle	0.045	0.954	0.000
M62.3 Immobility syndrome (paraplegic)	0.045	0.954	0.000
M62.2 Ischaemic infarction of muscle	0.045	0.954	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.045	0.954	0.000
M43.1 Spondylolisthesis	0.045	0.955	0.000
E24.2 Drug-induced Cushing's syndrome	0.000	0.955	0.045
E61 Deficiency of other nutrient elements	0.000	0.955	0.045
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)	0.045	0.955	0.000
M87.08 Idiopathic aseptic necrosis of bone (Other)	0.045	0.955	0.000
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)	0.045	0.955	0.000
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)	0.045	0.955	0.000
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)	0.045	0.955	0.000
M87.04 Idiopathic aseptic necrosis of bone (Hand)	0.045	0.955	0.000
M87.03 Idiopathic aseptic necrosis of bone (Forearm)	0.045	0.955	0.000
M87.02 Idiopathic aseptic necrosis of bone (Upper arm)	0.045	0.955	0.000
M87.01 Idiopathic aseptic necrosis of bone (Shoulder region)	0.045	0.955	0.000
M87.00 Idiopathic aseptic necrosis of bone (Multiple sites)	0.045	0.955	0.000
M87.19 Osteonecrosis due to drugs (Site unspecified)	0.045	0.955	0.000
M87.18 Osteonecrosis due to drugs (Other)	0.045	0.955	0.000
M87.17 Osteonecrosis due to drugs (Ankle and foot)	0.045	0.955	0.000
M87.16 Osteonecrosis due to drugs (Lower leg)	0.045	0.955	0.000
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)	0.045	0.955	0.000
M87.14 Osteonecrosis due to drugs (Hand)	0.045	0.955	0.000
M87.13 Osteonecrosis due to drugs (Forearm)	0.045	0.955	0.000
M87.12 Osteonecrosis due to drugs (Upper arm)	0.045	0.955	0.000
M87.11 Osteonecrosis due to drugs (Shoulder region)	0.045	0.955	0.000
M87.10 Osteonecrosis due to drugs (Multiple sites)	0.045	0.955	0.000
M87.39 Other secondary osteonecrosis (Site unspecified)	0.045	0.955	0.000
M87.38 Other secondary osteonecrosis (Other)	0.045	0.955	0.000
M87.37 Other secondary osteonecrosis (Ankle and foot)	0.045	0.955	0.000
M87.36 Other secondary osteonecrosis (Lower leg)	0.045	0.955	0.000
M87.35 Other secondary osteonecrosis (Pelvic region and thigh)	0.045	0.955	0.000
M87.34 Other secondary osteonecrosis (Hand)	0.045	0.955	0.000
M87.33 Other secondary osteonecrosis (Forearm)	0.045	0.955	0.000
M87.32 Other secondary osteonecrosis (Upper arm)	0.045	0.955	0.000
M87.31 Other secondary osteonecrosis (Shoulder region)	0.045	0.955	0.000
M87.30 Other secondary osteonecrosis (Multiple sites)	0.045	0.955	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.045	0.955	0.000
E26.9 Hyperaldosteronism, unspecified	0.000	0.955	0.045
E26.8 Other hyperaldosteronism	0.000	0.955	0.045
E26.1 Secondary hyperaldosteronism	0.000	0.955	0.045
L43.8 Other lichen planus	0.045	0.955	0.000
M89.98 Disorder of bone, unspecified (Other)	0.045	0.955	0.000
M00 Pyogenic arthritis	0.045	0.955	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.045	0.955	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.044	0.955	0.000
M89.18 Epiphyseal arrest (Other)	0.044	0.955	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.044	0.955	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.044	0.955	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.044	0.955	0.000
M89.14 Epiphyseal arrest (Hand)	0.044	0.955	0.000
M89.13 Epiphyseal arrest (Forearm)	0.044	0.955	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.044	0.955	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.044	0.955	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.044	0.955	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.044	0.955	0.000
M89.28 Other disorders of bone development and growth (Other)	0.044	0.955	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.044	0.955	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.044	0.955	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.044	0.955	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.044	0.955	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.044	0.955	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.044	0.955	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.044	0.955	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.044	0.955	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.044	0.955	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.044	0.955	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations