TreeWAS – Variant ID: rs9375969

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I31.3 Pericardial effusion (noninflammatory)	0.065	0.935	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.065	0.935	0.000
M06.9 Rheumatoid arthritis, unspecified	0.035	0.965	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.029	0.971	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.028	0.972	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.027	0.973	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.026	0.973	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.026	0.974	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.026	0.974	0.000
I31 Other diseases of pericardium	0.024	0.976	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.024	0.976	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.019	0.981	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.018	0.982	0.000
I31.1 Chronic constrictive pericarditis	0.018	0.982	0.000
I31.0 Chronic adhesive pericarditis	0.018	0.982	0.000
I31.8 Other specified diseases of pericardium	0.018	0.982	0.000
I31.2 Haemopericardium, not elsewhere classified	0.018	0.982	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.016	0.984	0.000
I31.9 Disease of pericardium, unspecified	0.015	0.985	0.000
L57.0 Actinic keratosis	0.000	0.986	0.014
K37 Unspecified appendicitis	0.014	0.986	0.000
Y43.3 Other antineoplastic drugs	0.011	0.989	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.011	0.989	0.000
Y42.7 Androgens and anabolic congeners	0.010	0.990	0.000
Y40.9 Systemic antibiotic, unspecified	0.010	0.990	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.990	0.010
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.010	0.990	0.000
Y43 Primarily systemic agents	0.010	0.990	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.010	0.990	0.000
Y40 Systemic antibiotics	0.009	0.991	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.009	0.991	0.000
Y43.1 Antineoplastic antimetabolites	0.009	0.991	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.009	0.991	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.009	0.991	0.000
Y42.4 Oral contraceptives	0.009	0.991	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.008	0.991	0.000
G47.3 Sleep apnoea	0.000	0.991	0.009
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.008	0.992	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.008	0.992	0.000
Y44 Agents primarily affecting blood constituents	0.008	0.992	0.000
Y40.5 Aminoglycosides	0.008	0.992	0.000
Y45.1 Salicylates	0.008	0.992	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.008	0.992	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.008	0.992	0.000
M89.9 Disorder of bone, unspecified	0.000	0.992	0.008
Y40.1 Cefalosporins and other -lactam antibiotics	0.008	0.992	0.000
Y42.9 Other and unspecified hormone antagonists	0.008	0.992	0.000
Y42.2 Antithyroid drugs	0.008	0.992	0.000
Y46.2 Hydantoin derivatives	0.008	0.992	0.000
N89.8 Other specified noninflammatory disorders of vagina	0.008	0.992	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.008	0.992	0.000
Y58 Bacterial vaccines	0.007	0.992	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.007	0.992	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.007	0.992	0.000
Y42.1 Thyroid hormones and substitutes	0.007	0.992	0.000
Y46.4 Iminostilbenes	0.007	0.992	0.000
Y43.9 Primarily systemic agent, unspecified	0.007	0.992	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.007	0.992	0.000
Y43.6 Enzymes, not elsewhere classified	0.007	0.992	0.000
Y43.5 Acidifying and alkalising agents	0.007	0.992	0.000
Y43.2 Antineoplastic natural products	0.007	0.992	0.000
Y41.1 Antimycobacterial drugs	0.007	0.993	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.007	0.993	0.000
M06 Other rheumatoid arthritis	0.007	0.993	0.000
Y41.0 Sulphonamides	0.007	0.993	0.000
Y45.8 Other analgesics and antipyretics	0.007	0.993	0.000
Y59 Other and unspecified vaccines and biological substances	0.007	0.993	0.000
Y40.6 Rifamycins	0.007	0.993	0.000
Y40.4 Tetracyclines	0.007	0.993	0.000
Y40.2 Chloramphenicol group	0.007	0.993	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.007	0.993	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.007	0.993	0.000
Y45.5 4-Aminophenol derivatives	0.007	0.993	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.007	0.993	0.000
Y45.4 Antirheumatics	0.007	0.993	0.000
Y55.4 Expectorants	0.007	0.993	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.000	0.993	0.007
Y48 Anaesthetics and therapeutic gases	0.007	0.993	0.000
Y40.7 Antifungal antibiotics, systemically used	0.007	0.993	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.007	0.993	0.000
Y41.4 Anthelminthics	0.007	0.993	0.000
Y41.3 Other antiprotozoal drugs	0.007	0.993	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.007	0.993	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.007	0.993	0.000
M89.98 Disorder of bone, unspecified (Other)	0.000	0.993	0.007
Y46.8 Antispasticity drugs	0.006	0.993	0.000
Y46.7 Anti-Parkinsonism drugs	0.006	0.993	0.000
Y46.5 Valproic acid	0.006	0.993	0.000
Y46.3 Deoxybarbiturates	0.006	0.993	0.000
Y46.1 Oxazolidinediones	0.006	0.993	0.000
Y46.0 Succinimides	0.006	0.993	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.007	0.993	0.000
Y44.2 Anticoagulants	0.007	0.993	0.000
K35-K38 Diseases of appendix	0.007	0.993	0.000
Y45.0 Opioids and related analgesics	0.007	0.993	0.000
Y52 Agents primarily affecting the cardiovascular system	0.007	0.993	0.000
J32.9 Chronic sinusitis, unspecified	0.007	0.993	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.006	0.994	0.000
Y44.7 Plasma substitutes	0.006	0.994	0.000
Y44.6 Natural blood and blood products	0.006	0.994	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.006	0.994	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.006	0.994	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.006	0.994	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.006	0.994	0.000
Y55.5 Anticommon cold drugs	0.006	0.994	0.000
Y55.3 Antitussives	0.006	0.994	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.006	0.994	0.000
Y55.0 Oxytocic drugs	0.006	0.994	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.006	0.994	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.006	0.994	0.000
K38 Other diseases of appendix	0.006	0.994	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.006	0.994	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.006	0.994	0.000
Y41.5 Antiviral drugs	0.006	0.994	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.006	0.994	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.000	0.994	0.006
Y44.5 Thrombolytic drugs	0.006	0.994	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.994	0.006
Y56.9 Topical agent, unspecified	0.006	0.994	0.000
Y56.8 Other topical agents	0.006	0.994	0.000
Y56.7 Dental drugs, topically applied	0.006	0.994	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.006	0.994	0.000
Y56.5 Ophthalmological drugs and preparations	0.006	0.994	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.006	0.994	0.000
Y56.3 Emollients, demulcents and protectants	0.006	0.994	0.000
Y56.2 Local astringents and local detergents	0.006	0.994	0.000
Y56.1 Antipruritics	0.006	0.994	0.000
Y43.4 Immunosuppressive agents	0.006	0.994	0.000
Y46.6 Other and unspecified antiepileptics	0.006	0.994	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.994	0.006
Y40.0 Penicillins	0.006	0.994	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.000	0.994	0.006
M89.93 Disorder of bone, unspecified (Forearm)	0.000	0.994	0.006
M89.90 Disorder of bone, unspecified (Multiple sites)	0.000	0.994	0.006
Y45.2 Propionic acid derivatives	0.006	0.994	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.000	0.994	0.006
K38.9 Disease of appendix, unspecified	0.006	0.994	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.000	0.994	0.006
Y50.9 Central nervous system stimulant, unspecified	0.005	0.994	0.000
Y50.8 Other central nervous system stimulants	0.005	0.994	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.005	0.994	0.000
Y50.1 Opioid receptor antagonists	0.005	0.994	0.000
Y50.0 Analeptics	0.005	0.994	0.000
Y58.9 Other and unspecified bacterial vaccines	0.005	0.994	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.005	0.994	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.005	0.994	0.000
Y58.5 Diphtheria vaccine	0.005	0.994	0.000
Y58.4 Tetanus vaccine	0.005	0.994	0.000
Y58.3 Plague vaccine	0.005	0.994	0.000
Y58.2 Cholera vaccine	0.005	0.994	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.005	0.994	0.000
Y58.0 BCG vaccine	0.005	0.994	0.000
R23.8 Other and unspecified skin changes	0.000	0.994	0.006
Y49.0 Tricyclic and tetracyclic antidepressants	0.005	0.994	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.000	0.994	0.005
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.005	0.994	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.005	0.994	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.005	0.994	0.000
Y47.4 Bromine compounds	0.005	0.994	0.000
Y47.3 Paraldehyde	0.005	0.994	0.000
Y47.2 Chloral derivatives	0.005	0.994	0.000
Y47.0 Barbiturates, not elsewhere classified	0.005	0.994	0.000
M06.8 Other specified rheumatoid arthritis	0.005	0.994	0.000
M06.2 Rheumatoid bursitis	0.005	0.994	0.000
M06.1 Adult-onset Still's disease	0.005	0.994	0.000
K36 Other appendicitis	0.005	0.994	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.000	0.994	0.005
Y49.2 Other and unspecified antidepressants	0.005	0.995	0.000
Y48.3 Local anaesthetics	0.005	0.995	0.000
K38.8 Other specified diseases of appendix	0.005	0.995	0.000
Y59.9 Vaccine or biological substance, unspecified	0.005	0.995	0.000
Y59.8 Other specified vaccines and biological substances	0.005	0.995	0.000
Y59.2 Protozoal vaccines	0.005	0.995	0.000
Y59.1 Rickettsial vaccines	0.005	0.995	0.000
Y59.0 Viral vaccines	0.005	0.995	0.000
K38.2 Diverticulum of appendix	0.005	0.995	0.000
Y47.1 Benzodiazepines	0.005	0.995	0.000
Y49.9 Psychotropic drug, unspecified	0.005	0.995	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
Y49.7 Psychostimulants with abuse potential	0.005	0.995	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.005	0.995	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.005	0.995	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.005	0.995	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.005	0.995	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.005	0.995	0.000
Y57 Other and unspecified drugs and medicaments	0.005	0.995	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.005	0.995	0.000
R23.2 Flushing	0.000	0.995	0.005
Y48.5 Therapeutic gases	0.005	0.995	0.000
Y48.1 Parenteral anaesthetics	0.005	0.995	0.000
Y48.0 Inhaled anaesthetics	0.005	0.995	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.005	0.995	0.000
Y54.8 Agents affecting uric acid metabolism	0.005	0.995	0.000
K38.0 Hyperplasia of appendix	0.005	0.995	0.000
Y52.7 Peripheral vasodilators	0.005	0.995	0.000
Y43.0 Antiallergic and antiemetic drugs	0.005	0.995	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.005	0.995	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.005	0.995	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.005	0.995	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.005	0.995	0.000
Y48.2 Other and unspecified general anaesthetics	0.005	0.995	0.000
Y54.4 Loop [high-ceiling] diuretics	0.005	0.995	0.000
Y59.3 Immunoglobulin	0.005	0.995	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.005	0.995	0.000
R23 Other skin changes	0.000	0.995	0.005
Y54.7 Agents affecting calcification	0.005	0.995	0.000
M06.3 Rheumatoid nodule	0.005	0.995	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.005	0.995	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.005	0.995	0.000
Y53.7 Emetics	0.005	0.995	0.000
Y53.6 Antidiarrhoeal drugs	0.005	0.995	0.000
Y53.5 Digestants	0.005	0.995	0.000
Y53.3 Saline and osmotic laxatives	0.005	0.995	0.000
Y53.2 Stimulant laxatives	0.005	0.995	0.000
Y53.0 Histamine H2-receptor antagonists	0.005	0.995	0.000
K38.3 Fistula of appendix	0.005	0.995	0.000
Y54.9 Mineral salts, not elsewhere classified	0.005	0.995	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.005	0.995	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.005	0.995	0.000
Y54.0 Mineralocorticoids	0.005	0.995	0.000
N89 Other noninflammatory disorders of vagina	0.005	0.995	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.005	0.995	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.005	0.995	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.005	0.995	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.005	0.995	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.005	0.995	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.005	0.995	0.000
Y51.0 Anticholinesterase agents	0.005	0.995	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.005	0.995	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.005	0.995	0.000
Y57.6 Other diagnostic agents	0.005	0.995	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.995	0.000
M06.4 Inflammatory polyarthropathy	0.004	0.995	0.000
Y52.1 Calcium-channel blockers	0.005	0.995	0.000
Y48.4 Anaesthetic, unspecified	0.004	0.996	0.000
Y40.3 Macrolides	0.004	0.996	0.000
Y40.8 Other systemic antibiotics	0.004	0.996	0.000
N89.6 Tight hymenal ring	0.004	0.996	0.000
Y53.4 Other laxatives	0.004	0.996	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.004	0.996	0.000
M06.18 Adult-onset Still's disease (Other)	0.004	0.996	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.004	0.996	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.004	0.996	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.004	0.996	0.000
M06.14 Adult-onset Still's disease (Hand)	0.004	0.996	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.004	0.996	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.004	0.996	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.004	0.996	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.004	0.996	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.004	0.996	0.000
M06.28 Rheumatoid bursitis (Other)	0.004	0.996	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.004	0.996	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.004	0.996	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.004	0.996	0.000
M06.24 Rheumatoid bursitis (Hand)	0.004	0.996	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.004	0.996	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.004	0.996	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.004	0.996	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.004	0.996	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.004	0.996	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.004	0.996	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.004	0.996	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.004	0.996	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.004	0.996	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.004	0.996	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.004	0.996	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.004	0.996	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.004	0.996	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.004	0.996	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.000	0.996	0.004
I63.9 Cerebral infarction, unspecified	0.000	0.996	0.004
L57.5 Actinic granuloma	0.000	0.996	0.004
L57.3 Poikiloderma of Civatte	0.000	0.996	0.004
L57.2 Cutis rhomboidalis nuchae	0.000	0.996	0.004
L57.1 Actinic reticuloid	0.000	0.996	0.004
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.000	0.996	0.004
M06.0 Seronegative rheumatoid arthritis	0.004	0.996	0.000
R23.0 Cyanosis	0.000	0.996	0.004
R23.4 Changes in skin texture	0.000	0.996	0.004
M06.32 Rheumatoid nodule (Upper arm)	0.004	0.996	0.000
R23.3 Spontaneous ecchymoses	0.000	0.996	0.004
N89.3 Dysplasia of vagina, unspecified	0.004	0.996	0.000
Y57.7 Vitamins, not elsewhere classified	0.004	0.996	0.000
Y57.4 Pharmaceutical excipients	0.004	0.996	0.000
Y57.3 Alcohol deterrents	0.004	0.996	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.004	0.996	0.000
Y57.1 Lipotropic drugs	0.004	0.996	0.000
Y57.0 Appetite depressants [anorectics]	0.004	0.996	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
Y49.5 Other antipsychotics and neuroleptics	0.004	0.996	0.000
N89.9 Noninflammatory disorder of vagina, unspecified	0.004	0.996	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.003	0.996	0.000
Y54.3 Benzothiadiazine derivatives	0.004	0.996	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.003	0.996	0.000
M06.38 Rheumatoid nodule (Other)	0.003	0.996	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.003	0.996	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.003	0.996	0.000
M06.33 Rheumatoid nodule (Forearm)	0.003	0.996	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.003	0.996	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.003	0.996	0.000
Y54.5 Other diuretics	0.003	0.996	0.000
M89 Other disorders of bone	0.000	0.996	0.004
N89.7 Haematocolpos	0.004	0.996	0.000
N89.4 Leukoplakia of vagina	0.004	0.996	0.000
N89.2 Severe vaginal dysplasia, not elsewhere classified	0.004	0.996	0.000
N89.1 Moderate vaginal dysplasia	0.004	0.996	0.000
N89.0 Mild vaginal dysplasia	0.004	0.996	0.000
K50.9 Crohn's disease, unspecified	0.000	0.996	0.004
M06.48 Inflammatory polyarthropathy (Other)	0.003	0.996	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.003	0.996	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.003	0.996	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.003	0.996	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.003	0.996	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.003	0.996	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.003	0.996	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.003	0.996	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.003	0.996	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.003	0.997	0.000
G47 Sleep disorders	0.000	0.997	0.003
K38.1 Appendicular concretions	0.003	0.997	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.003	0.997	0.000
Y42.5 Other oestrogens and progestogens	0.003	0.997	0.000
Y57.9 Drug or medicament, unspecified	0.003	0.997	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.003	0.997	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.003	0.997	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.003	0.997	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.003	0.997	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.003	0.997	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.003	0.997	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.003	0.997	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.003	0.997	0.000
Y57.8 Other drugs and medicaments	0.003	0.997	0.000
L57.4 Cutis laxa senilis	0.000	0.997	0.003
R22.1 Localised swelling, mass and lump, neck	0.003	0.997	0.000
M89.0 Algoneurodystrophy	0.000	0.997	0.003
R23.1 Pallor	0.000	0.997	0.003
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.003	0.997	0.000
G47.2 Disorders of the sleep-wake schedule	0.000	0.997	0.003
N89.5 Stricture and atresia of vagina	0.003	0.997	0.000
R06.2 Wheezing	0.003	0.997	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.003	0.997	0.000
M89.6 Osteopathy after poliomyelitis	0.000	0.997	0.003
M89.4 Other hypertrophic osteo-arthropathy	0.000	0.997	0.003
M89.2 Other disorders of bone development and growth	0.000	0.997	0.003
M89.1 Epiphyseal arrest	0.000	0.997	0.003
M89.8 Other specified disorders of bone	0.000	0.997	0.003
O20.9 Haemorrhage in early pregnancy, unspecified	0.003	0.997	0.000
Z09.8 Follow-up examination after other treatment for other conditions	0.003	0.997	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.003	0.997	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.000	0.997	0.003
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.000	0.997	0.003
M89.5 Osteolysis	0.000	0.997	0.003
Z92.3 Personal history of irradiation	0.003	0.997	0.000
S52.10 Fracture of upper end of radius (closed)	0.000	0.997	0.003
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.000	0.997	0.003
Y57.5 X-ray contrast media	0.002	0.997	0.000
M06.34 Rheumatoid nodule (Hand)	0.002	0.997	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.000	0.997	0.003
D12.5 Sigmoid colon	0.003	0.997	0.000
N81.4 Uterovaginal prolapse, unspecified	0.003	0.997	0.000
K29.7 Gastritis, unspecified	0.003	0.997	0.000
M89.3 Hypertrophy of bone	0.000	0.997	0.002
M89.03 Algoneurodystrophy (Forearm)	0.000	0.997	0.002
I89.0 Lymphoedema, not elsewhere classified	0.000	0.997	0.003
M89.04 Algoneurodystrophy (Hand)	0.000	0.997	0.002
M89.07 Algoneurodystrophy (Ankle and foot)	0.000	0.997	0.002
M89.09 Algoneurodystrophy (Site unspecified)	0.000	0.997	0.002
M89.08 Algoneurodystrophy (Other)	0.000	0.997	0.002
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.000	0.997	0.002
M89.02 Algoneurodystrophy (Upper arm)	0.000	0.997	0.002
M89.01 Algoneurodystrophy (Shoulder region)	0.000	0.997	0.002
M89.00 Algoneurodystrophy (Multiple sites)	0.000	0.997	0.002
G47.9 Sleep disorder, unspecified	0.000	0.997	0.002
G47.4 Narcolepsy and cataplexy	0.000	0.997	0.002
J32.4 Chronic pansinusitis	0.002	0.998	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.000	0.998	0.002
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.002	0.998	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.000	0.998	0.002
M89.19 Epiphyseal arrest (Site unspecified)	0.000	0.998	0.002
M89.18 Epiphyseal arrest (Other)	0.000	0.998	0.002
M89.17 Epiphyseal arrest (Ankle and foot)	0.000	0.998	0.002
M89.16 Epiphyseal arrest (Lower leg)	0.000	0.998	0.002
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.000	0.998	0.002
M89.14 Epiphyseal arrest (Hand)	0.000	0.998	0.002
M89.13 Epiphyseal arrest (Forearm)	0.000	0.998	0.002
M89.12 Epiphyseal arrest (Upper arm)	0.000	0.998	0.002
M89.11 Epiphyseal arrest (Shoulder region)	0.000	0.998	0.002
M89.10 Epiphyseal arrest (Multiple sites)	0.000	0.998	0.002
M89.29 Other disorders of bone development and growth (Site unspecified)	0.000	0.998	0.002
M89.28 Other disorders of bone development and growth (Other)	0.000	0.998	0.002
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.000	0.998	0.002
M89.26 Other disorders of bone development and growth (Lower leg)	0.000	0.998	0.002
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.000	0.998	0.002
M89.24 Other disorders of bone development and growth (Hand)	0.000	0.998	0.002
M89.23 Other disorders of bone development and growth (Forearm)	0.000	0.998	0.002
M89.22 Other disorders of bone development and growth (Upper arm)	0.000	0.998	0.002
M89.21 Other disorders of bone development and growth (Shoulder region)	0.000	0.998	0.002
M89.20 Other disorders of bone development and growth (Multiple sites)	0.000	0.998	0.002
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.000	0.998	0.002
M89.48 Other hypertrophic osteoarthropathy (Other)	0.000	0.998	0.002
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.000	0.998	0.002
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.000	0.998	0.002
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.000	0.998	0.002
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.000	0.998	0.002
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.000	0.998	0.002
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.000	0.998	0.002
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.000	0.998	0.002
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.000	0.998	0.002
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.000	0.998	0.002
M89.68 Osteopathy after poliomyelitis (Other)	0.000	0.998	0.002
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.000	0.998	0.002
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.000	0.998	0.002
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.000	0.998	0.002
M89.64 Osteopathy after poliomyelitis (Hand)	0.000	0.998	0.002
M89.63 Osteopathy after poliomyelitis (Forearm)	0.000	0.998	0.002
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.000	0.998	0.002
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.000	0.998	0.002
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.000	0.998	0.002
M89.84 Other specified disorders of bone (Hand)	0.000	0.998	0.002
M89.83 Other specified disorders of bone (Forearm)	0.000	0.998	0.002
M89.82 Other specified disorders of bone (Upper arm)	0.000	0.998	0.002
M89.80 Other specified disorders of bone (Multiple sites)	0.000	0.998	0.002
Z09.0 Follow-up examination after surgery for other conditions	0.002	0.998	0.000
D33.3 Cranial nerves	0.002	0.998	0.000
R30.0 Dysuria	0.002	0.998	0.000
J32 Chronic sinusitis	0.002	0.998	0.000
M89.59 Osteolysis (Site unspecified)	0.000	0.998	0.002
M89.58 Osteolysis (Other)	0.000	0.998	0.002
M89.57 Osteolysis (Ankle and foot)	0.000	0.998	0.002
M89.56 Osteolysis (Lower leg)	0.000	0.998	0.002
M89.54 Osteolysis (Hand)	0.000	0.998	0.002
M89.53 Osteolysis (Forearm)	0.000	0.998	0.002
M89.52 Osteolysis (Upper arm)	0.000	0.998	0.002
M89.51 Osteolysis (Shoulder region)	0.000	0.998	0.002
M89.50 Osteolysis (Multiple sites)	0.000	0.998	0.002
J01.9 Acute sinusitis, unspecified	0.002	0.998	0.000
R80 Isolated proteinuria	0.000	0.998	0.002
I20.1 Angina pectoris with documented spasm	0.002	0.998	0.000
K50.8 Other Crohn's disease	0.000	0.998	0.002
K72.0 Acute and subacute hepatic failure	0.002	0.998	0.000
M31.3 Wegener's granulomatosis	0.002	0.998	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.000	0.998	0.002
K50 Crohn's disease [regional enteritis]	0.000	0.998	0.002
M89.39 Hypertrophy of bone (Site unspecified)	0.000	0.998	0.002
M89.36 Hypertrophy of bone (Lower leg)	0.000	0.998	0.002
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.000	0.998	0.002
M89.34 Hypertrophy of bone (Hand)	0.000	0.998	0.002
M89.33 Hypertrophy of bone (Forearm)	0.000	0.998	0.002
M89.32 Hypertrophy of bone (Upper arm)	0.000	0.998	0.002
M89.31 Hypertrophy of bone (Shoulder region)	0.000	0.998	0.002
M89.30 Hypertrophy of bone (Multiple sites)	0.000	0.998	0.002
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M89.88 Other specified disorders of bone (Other)	0.000	0.998	0.002
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
B07 Viral warts	0.000	0.998	0.002
M89.38 Hypertrophy of bone (Other)	0.000	0.998	0.002
M89.55 Osteolysis (Pelvic region and thigh)	0.000	0.998	0.002
J32.8 Other chronic sinusitis	0.002	0.998	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
Z92.6 Personal history of chemotherapy for neoplastic disease	0.002	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.002	0.998	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.000	0.998	0.002
T92.1 Sequelae of fracture of arm	0.000	0.998	0.002
J32.3 Chronic sphenoidal sinusitis	0.002	0.998	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
K50.1 Crohn's disease of large intestine	0.000	0.998	0.002
M22.2 Patellofemoral disorders	0.000	0.998	0.002
G47.8 Other sleep disorders	0.000	0.998	0.002
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.002	0.998	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.002	0.998	0.000
R91 Abnormal findings on diagnostic imaging of lung	0.002	0.998	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.000	0.998	0.002
K35 Acute appendicitis	0.002	0.998	0.000
J32.1 Chronic frontal sinusitis	0.002	0.998	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.998	0.002
R49.0 Dysphonia	0.002	0.998	0.000
K35.3 Acute appendicitis with localized peritonitis	0.000	0.998	0.001
M80 Osteoporosis with pathological fracture	0.002	0.998	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.002	0.998	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.002	0.998	0.000
Z03.3 Observation for suspected nervous system disorder	0.000	0.998	0.002
Z63.8 Other specified problems related to primary support group	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.002	0.998	0.000
M80.8 Other osteoporosis with pathological fracture	0.002	0.998	0.000
S42.20 Fracture of upper end of humerus (closed)	0.002	0.998	0.000
K72.9 Hepatic failure, unspecified	0.002	0.998	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.001	0.998	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations