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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9379842
log Bayes Factor = 47.8805
Chromosome 6   position 26,289,310  (GRCh37) Explore rs9379842 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.013 0.987
E10-E14 Diabetes mellitus
0.000 0.014 0.986
E10 Insulin-dependent diabetes mellitus
0.000 0.018 0.982
E11.2 With renal complications
0.000 0.041 0.959
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.052 0.948
E83 Disorders of mineral metabolism
0.000 0.058 0.942
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.063 0.937
E70-E90 Metabolic disorders
0.000 0.070 0.930
E16 Other disorders of pancreatic internal secretion
0.000 0.071 0.929
I10 Essential (primary) hypertension
0.000 0.075 0.925
E16.2 Hypoglycaemia, unspecified
0.000 0.076 0.924
E10.0 With coma
0.000 0.088 0.912
E10.5 With peripheral circulatory complications
0.000 0.101 0.899
E11.5 With peripheral circulatory complications
0.000 0.102 0.898
E11.3 With ophthalmic complications
0.000 0.105 0.895
E10.3 With ophthalmic complications
0.000 0.123 0.877
E11.4 With neurological complications
0.000 0.125 0.875
E11.9 Without complications
0.000 0.128 0.872
E40-E46 Malnutrition
0.000 0.140 0.860
E10.1 With ketoacidosis
0.000 0.142 0.858
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.191 0.809
E46 Unspecified protein-energy malnutrition
0.000 0.203 0.797
E11.6 With other specified complications
0.000 0.213 0.787
E88 Other metabolic disorders
0.000 0.220 0.780
E10.8 With unspecified complications
0.000 0.231 0.769
E11.1 With ketoacidosis
0.000 0.255 0.745
E73 Lactose intolerance
0.000 0.256 0.744
E10.2 With renal complications
0.000 0.263 0.737
E14 Unspecified diabetes mellitus
0.000 0.263 0.737
E11.0 With coma
0.000 0.273 0.727
E84 Cystic fibrosis
0.000 0.275 0.725
E80.4 Gilbert's syndrome
0.000 0.284 0.716
E11.7 With multiple complications
0.000 0.292 0.707
E12 Malnutrition-related diabetes mellitus
0.000 0.293 0.707
E10.7 With multiple complications
0.000 0.296 0.704
E79 Disorders of purine and pyrimidine metabolism
0.000 0.312 0.688
E10.9 Without complications
0.000 0.316 0.684
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.324 0.675
E83.8 Other disorders of mineral metabolism
0.000 0.324 0.675
E83.2 Disorders of zinc metabolism
0.000 0.324 0.675
E83.0 Disorders of copper metabolism
0.000 0.324 0.675
E10.4 With neurological complications
0.000 0.325 0.675
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.328 0.672
E15 Nondiabetic hypoglycaemic coma
0.000 0.328 0.671
E76 Disorders of glycosaminoglycan metabolism
0.000 0.333 0.667
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.333 0.667
E70 Disorders of aromatic amino-acid metabolism
0.000 0.333 0.667
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.333 0.667
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.334 0.666
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.334 0.666
E16.4 Abnormal secretion of gastrin
0.000 0.334 0.666
E16.3 Increased secretion of glucagon
0.000 0.334 0.666
E14.3 With ophthalmic complications
0.000 0.336 0.664
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.340 0.659
E13 Other specified diabetes mellitus
0.000 0.351 0.649
E16.1 Other hypoglycaemia
0.000 0.352 0.648
E88.8 Other specified metabolic disorders
0.000 0.359 0.641
E83.3 Disorders of phosphorus metabolism
0.000 0.365 0.634
E77 Disorders of glycoprotein metabolism
0.000 0.366 0.634
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.367 0.633
E80.2 Other porphyria
0.000 0.368 0.632
E10.6 With other specified complications
0.000 0.374 0.626
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.384 0.616
E45 Retarded development following protein-energy malnutrition
0.000 0.384 0.616
E43 Unspecified severe protein-energy malnutrition
0.000 0.384 0.616
E42 Marasmic kwashiorkor
0.000 0.384 0.616
E41 Nutritional marasmus
0.000 0.384 0.616
E40 Kwashiorkor
0.000 0.384 0.616
E73.9 Lactose intolerance, unspecified
0.000 0.389 0.611
E14.6 With other specified complications
0.000 0.395 0.605
E72 Other disorders of amino-acid metabolism
0.000 0.402 0.598
E74 Other disorders of carbohydrate metabolism
0.000 0.419 0.580
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.420 0.580
E80.5 Crigler-Najjar syndrome
0.000 0.420 0.580
E80.3 Defects of catalase and peroxydase
0.000 0.420 0.580
E80.1 Porphyria cutanea tarda
0.000 0.420 0.580
E80.0 Hereditary erythropoietic porphyria
0.000 0.420 0.580
E84.9 Cystic fibrosis, unspecified
0.000 0.422 0.578
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.424 0.576
E83.4 Disorders of magnesium metabolism
0.000 0.438 0.562
E88.3 Tumour lysis syndrome
0.000 0.441 0.559
E14.5 With peripheral circulatory complications
0.000 0.444 0.556
E88.9 Metabolic disorder, unspecified
0.000 0.449 0.551
E14.1 With ketoacidosis
0.000 0.463 0.537
E80.6 Other disorders of bilirubin metabolism
0.000 0.465 0.535
E73.8 Other lactose intolerance
0.000 0.466 0.534
E73.1 Secondary lactase deficiency
0.000 0.466 0.534
E73.0 Congenital lactase deficiency
0.000 0.466 0.534
E14.8 With unspecified complications
0.000 0.468 0.531
E14.7 With multiple complications
0.000 0.472 0.528
E14.0 With coma
0.000 0.472 0.528
E84.8 Cystic fibrosis with other manifestations
0.000 0.480 0.520
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.480 0.520
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.480 0.520
E11.8 With unspecified complications
0.000 0.481 0.519
E65-E68 Obesity and other hyperalimentation
0.000 0.483 0.517
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.486 0.514
E88.2 Lipomatosis, not elsewhere classified
0.000 0.489 0.511
E12.9 Without complications
0.000 0.493 0.507
E12.8 With unspecified complications
0.000 0.493 0.507
E12.7 With multiple complications
0.000 0.493 0.507
E12.6 With other specified complications
0.000 0.493 0.507
E12.5 With peripheral circulatory complications
0.000 0.493 0.507
E12.4 With neurological complications
0.000 0.493 0.507
E12.3 With ophthalmic complications
0.000 0.493 0.507
E12.2 With renal complications
0.000 0.493 0.507
E12.1 With ketoacidosis
0.000 0.493 0.507
E12.0 With coma
0.000 0.493 0.507
E14.4 With neurological complications
0.000 0.504 0.496
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.507 0.493
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.507 0.493
E79.1 Lesch-Nyhan syndrome
0.000 0.507 0.493
E75.5 Other lipid storage disorders
0.000 0.513 0.487
E75.6 Lipid storage disorder, unspecified
0.000 0.518 0.482
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.518 0.482
E75.3 Sphingolipidosis, unspecified
0.000 0.518 0.482
E75.2 Other sphingolipidosis
0.000 0.518 0.482
E75.1 Other gangliosidosis
0.000 0.518 0.482
E75.0 GM2 gangliosidosis
0.000 0.518 0.482
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.522 0.478
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.522 0.478
E70.3 Albinism
0.000 0.522 0.478
E70.2 Disorders of tyrosine metabolism
0.000 0.522 0.478
E70.1 Other hyperphenylalaninaemias
0.000 0.522 0.478
E70.0 Classical phenylketonuria
0.000 0.522 0.478
E71.3 Disorders of fatty-acid metabolism
0.000 0.522 0.478
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.522 0.478
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.522 0.478
E71.0 Maple-syrup-urine disease
0.000 0.522 0.478
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.522 0.478
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.522 0.478
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.522 0.478
E76.2 Other mucopolysaccharidoses
0.000 0.522 0.478
E76.1 Mucopolysaccharidosis, type II
0.000 0.522 0.478
E76.0 Mucopolysaccharidosis, type I
0.000 0.522 0.478
E13.3 With ophthalmic complications
0.000 0.529 0.471
E13.8 With unspecified complications
0.000 0.534 0.465
E13.7 With multiple complications
0.000 0.534 0.465
E13.6 With other specified complications
0.000 0.534 0.465
E13.5 With peripheral circulatory complications
0.000 0.534 0.465
E13.4 With neurological complications
0.000 0.534 0.465
E13.2 With renal complications
0.000 0.534 0.465
E13.1 With ketoacidosis
0.000 0.534 0.465
E13.0 With coma
0.000 0.534 0.465
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.545 0.454
E77.1 Defects in glycoprotein degradation
0.000 0.545 0.454
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.545 0.454
E44.1 Mild protein-energy malnutrition
0.000 0.558 0.442
E44.0 Moderate protein-energy malnutrition
0.000 0.558 0.442
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.571 0.429
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.571 0.429
E72.5 Disorders of glycine metabolism
0.000 0.571 0.429
E72.4 Disorders of ornithine metabolism
0.000 0.571 0.429
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.571 0.429
E72.2 Disorders of urea cycle metabolism
0.000 0.571 0.429
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.571 0.429
E77.8 Other disorders of glycoprotein metabolism
0.000 0.579 0.421
E14.2 Withrenal complications
0.000 0.582 0.417
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.584 0.416
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.584 0.416
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.584 0.416
E74.2 Disorders of galactose metabolism
0.000 0.584 0.416
E74.1 Disorders of fructose metabolism
0.000 0.584 0.416
E65 Localised adiposity
0.000 0.585 0.415
E74.0 Glycogen storage disease
0.000 0.598 0.401
E13.9 Without complications
0.000 0.600 0.400
E83.5 Disorders of calcium metabolism
0.000 0.606 0.394
E67 Other hyperalimentation
0.000 0.629 0.371
E68 Sequelae of hyperalimentation
0.000 0.629 0.371
E85 Amyloidosis
0.001 0.640 0.360
E72.0 Disorders of amino-acid transport
0.000 0.640 0.359
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.649 0.351
K90 Intestinal malabsorption
0.000 0.698 0.302
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.706 0.294
E00-E07 Disorders of thyroid gland
0.000 0.712 0.288
E85.8 Other amyloidosis
0.001 0.733 0.266
E67.8 Other specified hyperalimentation
0.000 0.734 0.266
E67.3 Hypervitaminosis D
0.000 0.734 0.266
E67.2 Megavitamin-B6 syndrome
0.000 0.734 0.266
E67.1 Hypercarotenaemia
0.000 0.734 0.266
E67.0 Hypervitaminosis A
0.000 0.734 0.266
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.741 0.258
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.741 0.258
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.741 0.258
E89.4 Postprocedural ovarian failure
0.000 0.749 0.251
E03 Other hypothyroidism
0.000 0.751 0.249
E50-E64 Other nutritional deficiencies
0.001 0.757 0.242
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.776 0.224
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.777 0.222
K90.3 Pancreatic steatorrhoea
0.000 0.783 0.217
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.783 0.217
K90.1 Tropical sprue
0.000 0.783 0.217
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.789 0.211
E89.1 Postprocedural hypoinsulinaemia
0.000 0.789 0.211
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.790 0.210
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.793 0.207
E00 Congenital iodine-deficiency syndrome
0.000 0.793 0.207
E85.4 Organ-limited amyloidosis
0.001 0.794 0.206
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.799 0.201
K90.9 Intestinal malabsorption, unspecified
0.000 0.803 0.197
E85.9 Amyloidosis, unspecified
0.001 0.806 0.193
E89.5 Postprocedural testicular hypofunction
0.000 0.808 0.192
I10-I15 Hypertensive diseases
0.000 0.811 0.189
E03.8 Other specified hypothyroidism
0.000 0.814 0.186
K90.8 Other intestinal malabsorption
0.000 0.815 0.185
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.815 0.185
E56 Other vitamin deficiencies
0.001 0.816 0.184
E85.3 Secondary systemic amyloidosis
0.001 0.819 0.180
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.820 0.180
E05.9 Thyrotoxicosis, unspecified
0.000 0.820 0.180
E03.5 Myxoedema coma
0.000 0.821 0.179
E03.4 Atrophy of thyroid (acquired)
0.000 0.821 0.179
E03.3 Postinfectious hypothyroidism
0.000 0.821 0.179
E03.1 Congenital hypothyroidism without goitre
0.000 0.821 0.179
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.825 0.175
E64 Sequelae of malnutrition and other nutritional deficiencies
0.001 0.825 0.174
E63 Other nutritional deficiencies
0.001 0.825 0.174
E50 Vitamin A deficiency
0.001 0.825 0.174
E60 Dietary zinc deficiency
0.001 0.825 0.174
E59 Dietary selenium deficiency
0.001 0.825 0.174
E54 Ascorbic acid deficiency
0.001 0.825 0.174
E52 Niacin deficiency [pellagra]
0.001 0.825 0.174
E06 Thyroiditis
0.000 0.827 0.173
E03.9 Hypothyroidism, unspecified
0.000 0.828 0.172
E58 Dietary calcium deficiency
0.001 0.830 0.169
E14.9 Without complications
0.000 0.831 0.169
E51 Thiamine deficiency
0.001 0.835 0.164
E05.8 Other thyrotoxicosis
0.000 0.840 0.160
E89.3 Postprocedural hypopituitarism
0.000 0.840 0.159
E89.2 Postprocedural hypoparathyroidism
0.000 0.849 0.151
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.851 0.148
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.851 0.148
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.851 0.148
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.851 0.148
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.851 0.148
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.851 0.148
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.851 0.148
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.851 0.148
I11 Hypertensive heart disease
0.000 0.853 0.147
E05.5 Thyroid crisis or storm
0.000 0.855 0.145
E05.4 Thyrotoxicosis factitia
0.000 0.855 0.145
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.855 0.145
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.855 0.145
E56.1 Deficiency of vitamin K
0.000 0.858 0.141
E86 Volume depletion
0.000 0.859 0.141
E06.3 Autoimmune thyroiditis
0.000 0.863 0.137
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.867 0.132
I13 Hypertensive heart and renal disease
0.000 0.868 0.132
E56.9 Vitamin deficiency, unspecified
0.001 0.868 0.132
E56.8 Deficiency of other vitamins
0.001 0.868 0.132
E56.0 Deficiency of vitamin E
0.001 0.868 0.132
E07 Other disorders of thyroid
0.000 0.871 0.129
E50.9 Vitamin A deficiency, unspecified
0.001 0.875 0.125
E50.8 Other manifestations of vitamin A deficiency
0.001 0.875 0.125
E50.7 Other ocular manifestations of vitamin A deficiency
0.001 0.875 0.125
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.001 0.875 0.125
E50.5 Vitamin A deficiency with night blindness
0.001 0.875 0.125
E50.4 Vitamin A deficiency with keratomalacia
0.001 0.875 0.125
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.001 0.875 0.125
E50.2 Vitamin A deficiency with corneal xerosis
0.001 0.875 0.125
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.001 0.875 0.125
E50.0 Vitamin A deficiency with conjunctival xerosis
0.001 0.875 0.125
E63.9 Nutritional deficiency, unspecified
0.001 0.875 0.125
E63.8 Other specified nutritional deficiencies
0.001 0.875 0.125
E63.1 Imbalance of constituents of food intake
0.001 0.875 0.125
E63.0 Essential fatty acid [EFA] deficiency
0.001 0.875 0.125
E64.9 Sequelae of unspecified nutritional deficiency
0.001 0.875 0.125
E64.8 Sequelae of other nutritional deficiencies
0.001 0.875 0.125
E64.3 Sequelae of rickets
0.001 0.875 0.125
E64.2 Sequelae of vitamin C deficiency
0.001 0.875 0.125
E64.1 Sequelae of vitamin A deficiency
0.001 0.875 0.125
E64.0 Sequelae of protein-energy malnutrition
0.001 0.875 0.125
E06.4 Drug-induced thyroiditis
0.000 0.876 0.124
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.876 0.124
E06.0 Acute thyroiditis
0.000 0.876 0.124
I15 Secondary hypertension
0.000 0.881 0.119
E51.9 Thiamine deficiency, unspecified
0.001 0.882 0.118
E51.8 Other manifestations of thiamine deficiency
0.001 0.882 0.118
E51.1 Beriberi
0.001 0.882 0.118
E06.9 Thyroiditis, unspecified
0.000 0.882 0.118
E53 Deficiency of other B group vitamins
0.000 0.882 0.117
E61 Deficiency of other nutrient elements
0.001 0.890 0.109
E51.2 Wernicke's encephalopathy
0.001 0.891 0.108
E06.5 Other chronic thyroiditis
0.000 0.892 0.108
E55 Vitamin D deficiency
0.001 0.892 0.106
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.896 0.103
E20-E35 Disorders of other endocrine glands
0.000 0.897 0.103
E06.1 Subacute thyroiditis
0.000 0.903 0.097
I15.9 Seconday hypertension, unspecified
0.000 0.904 0.096
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.905 0.095
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.905 0.095
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.905 0.095
E07.1 Dyshormogenetic goitre
0.000 0.907 0.092
E07.0 Hypersecretion of calcitonin
0.000 0.907 0.092
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.908 0.092
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.910 0.090
I15.8 Other secondary hypertension
0.000 0.915 0.085
E53.1 Pyridoxine deficiency
0.000 0.915 0.084
E53.0 Riboflavin deficiency
0.000 0.915 0.084
I15.2 Hypertension secondary to endocrine disorders
0.000 0.916 0.084
E20 Hypoparathyroidism
0.000 0.917 0.083
E07.8 Other specified disorders of thyroid
0.000 0.918 0.082
I15.0 Renovascular hypertension
0.000 0.919 0.081
E61.9 Deficiency of nutrient element, unspecified
0.001 0.921 0.078
E61.8 Deficiency of other specified nutrient elements
0.001 0.921 0.078
E61.7 Deficiency of multiple nutrient elements
0.001 0.921 0.078
E61.6 Vanadium deficiency
0.001 0.921 0.078
E61.5 Molybdenum deficiency
0.001 0.921 0.078
E61.4 Chromium deficiency
0.001 0.921 0.078
E61.3 Manganese deficiency
0.001 0.921 0.078
E61.0 Copper deficiency
0.001 0.921 0.078
E55.0 Rickets, active
0.001 0.922 0.076
E66 Obesity
0.000 0.922 0.077
E29 Testicular dysfunction
0.000 0.923 0.077
E25 Adrenogenital disorders
0.000 0.923 0.077
R40.0 Somnolence
0.075 0.925 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.926 0.074
E32 Diseases of thymus
0.000 0.926 0.074
E31 Polyglandular dysfunction
0.000 0.926 0.074
E30 Disorders of puberty, not elsewhere classified
0.000 0.926 0.074
E89.0 Postprocedural hypothyroidism
0.000 0.927 0.073
E53.9 Vitamin B deficiency, unspecified
0.000 0.929 0.071
E26 Hyperaldosteronism
0.000 0.929 0.071
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.930 0.070
E20.9 Hypoparathyroidism, unspecified
0.000 0.931 0.069
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.932 0.068
E61.2 Magnesium deficiency
0.001 0.932 0.067
E34 Other endocrine disorders
0.000 0.933 0.067
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.933 0.067
E27 Other disorders of adrenal gland
0.000 0.934 0.066
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.936 0.064
E29.1 Testicular hypofunction
0.000 0.939 0.061
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.940 0.060
E20.8 Other hypoparathyroidism
0.000 0.940 0.060
E20.1 Pseudohypoparathyroidism
0.000 0.940 0.060
E20.0 Idiopathic hypoparathyroidism
0.000 0.940 0.060
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.941 0.058
I15.1 Hypertension secondary to other renal disorders
0.000 0.942 0.057
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.943 0.057
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.944 0.056
E78.4 Other hyperlipidaemia
0.000 0.944 0.056
E66.1 Drug-induced obesity
0.000 0.944 0.056
E29.8 Other testicular dysfunction
0.000 0.944 0.056
E29.0 Testicular hyperfunction
0.000 0.944 0.056
E25.9 Adrenogenital disorder, unspecified
0.000 0.944 0.055
E25.8 Other adrenogenital disorders
0.000 0.944 0.055
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.945 0.055
E78.1 Pure hyperglyceridaemia
0.000 0.945 0.055
E26.9 Hyperaldosteronism, unspecified
0.000 0.946 0.054
E30.9 Disorder of puberty, unspecified
0.000 0.946 0.053
E30.8 Other disorders of puberty
0.000 0.946 0.053
E30.1 Precocious puberty
0.000 0.946 0.053
E30.0 Delayed puberty
0.000 0.946 0.053
E31.9 Polyglandular dysfunction, unspecified
0.000 0.946 0.053
E31.8 Other polyglandular dysfunction
0.000 0.946 0.053
E31.1 Polyglandular hyperfunction
0.000 0.946 0.053
E31.0 Autoimmune polyglandular failure
0.000 0.946 0.053
E32.9 Disease of thymus, unspecified
0.000 0.946 0.053
E32.8 Other diseases of thymus
0.000 0.946 0.053
E32.1 Abscess of thymus
0.000 0.946 0.053
E32.0 Persistent hyperplasia of thymus
0.000 0.946 0.053
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.946 0.053
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.946 0.053
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.946 0.053
E34.9 Endocrine disorder, unspecified
0.000 0.947 0.053
E53.8 Deficiency of other specified B group vitamins
0.000 0.947 0.053
E29.9 Testicular dysfunction, unspecified
0.000 0.948 0.052
E27.1 Primary adrenocortical insufficiency
0.000 0.948 0.052
E21.2 Other hyperparathyroidism
0.000 0.948 0.052
I12 Hypertensive renal disease
0.000 0.948 0.052
E87.5 Hyperkalaemia
0.000 0.949 0.051
E26.8 Other hyperaldosteronism
0.000 0.949 0.051
E26.1 Secondary hyperaldosteronism
0.000 0.949 0.051
E78.6 Lipoprotein deficiency
0.000 0.949 0.051
E24 Cushing's syndrome
0.000 0.951 0.049
E34.8 Other specified endocrine disorders
0.000 0.951 0.049
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.951 0.049
E28 Ovarian dysfunction
0.000 0.951 0.049
E34.5 Androgen resistance syndrome
0.000 0.952 0.048
E34.4 Constitutional tall stature
0.000 0.952 0.048
E34.3 Short stature, not elsewhere classified
0.000 0.952 0.048
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.952 0.048
E34.1 Other hypersecretion of intestinal hormones
0.000 0.952 0.048
E21.4 Other specified disorders of parathyroid gland
0.000 0.952 0.048
E78.3 Hyperchylomicronaemia
0.000 0.952 0.048
E27.5 Adrenomedullary hyperfunction
0.000 0.952 0.047
E27.0 Other adrenocortical overactivity
0.000 0.952 0.047
E27.2 Addisonian crisis
0.000 0.953 0.047
E22 Hyperfunction of pituitary gland
0.000 0.953 0.046
E26.0 Primary hyperaldosteronism
0.000 0.955 0.044
E27.9 Disorder of adrenal gland, unspecified
0.000 0.957 0.042
E27.8 Other specified disorders of adrenal gland
0.000 0.958 0.042
E87.3 Alkalosis
0.000 0.959 0.041
E07.9 Disorder of thyroid, unspecified
0.000 0.959 0.040
E87.4 Mixed disorder of acid-base balance
0.000 0.960 0.040
E61.1 Iron deficiency
0.001 0.962 0.038
E87.0 Hyperosmolality and hypernatraemia
0.000 0.962 0.038
E22.1 Hyperprolactinaemia
0.000 0.963 0.037
E24.2 Drug-induced Cushing's syndrome
0.000 0.963 0.036
E21.0 Primary hyperparathyroidism
0.000 0.964 0.036
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.964 0.035
E24.3 Ectopic ACTH syndrome
0.000 0.964 0.035
E24.1 Nelson's syndrome
0.000 0.964 0.035
E78.8 Other disorders of lipoprotein metabolism
0.000 0.964 0.035
E28.9 Ovarian dysfunction, unspecified
0.000 0.965 0.035
E28.8 Other ovarian dysfunction
0.000 0.965 0.035
E28.1 Androgen excess
0.000 0.965 0.035
E28.0 Oestrogen excess
0.000 0.965 0.035
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.965 0.035
E66.0 Obesity due to excess calories
0.000 0.966 0.033
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.966 0.033
E22.8 Other hyperfunction of pituitary gland
0.000 0.966 0.033
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.967 0.033
E78.2 Mixed hyperlipidaemia
0.000 0.968 0.032
E28.3 Primary ovarian failure
0.000 0.968 0.032
E23 Hypofunction and other disorders of pituitary gland
0.000 0.968 0.032
E24.0 Pituitary-dependent Cushing's disease
0.000 0.968 0.031
D45 Polycythaemia vera
0.000 0.969 0.031
E34.0 Carcinoid syndrome
0.000 0.970 0.030
I83 Varicose veins of lower extremities
0.000 0.970 0.030
E24.8 Other Cushing's syndrome
0.000 0.970 0.030
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.972 0.028
E22.0 Acromegaly and pituitary gigantism
0.000 0.973 0.026
E21.3 Hyperparathyroidism, unspecified
0.000 0.974 0.026
E24.9 Cushing's syndrome, unspecified
0.000 0.974 0.025
K90-K93 Other diseases of the digestive system
0.000 0.975 0.025
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.975 0.025
E04 Other non-toxic goitre
0.000 0.975 0.025
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.977 0.023
E23.1 Drug-induced hypopituitarism
0.000 0.977 0.023
E23.7 Disorder of pituitary gland, unspecified
0.000 0.978 0.022
I12.9 Hypertensive renal disease without renal failure
0.000 0.978 0.022
E23.2 Diabetes insipidus
0.000 0.979 0.020
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.981 0.019
E23.6 Other disorders of pituitary gland
0.000 0.981 0.019
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.982 0.018
E04.8 Other specified non-toxic goitre
0.000 0.982 0.018
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.982 0.018
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.000 0.983 0.017
D46 Myelodysplastic syndromes
0.000 0.983 0.017
E28.2 Polycystic ovarian syndrome
0.000 0.984 0.016
D39.1 Ovary
0.000 0.984 0.016
E66.8 Other obesity
0.000 0.984 0.016
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.000 0.984 0.016
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.984 0.016
H57.9 Disorder of eye and adnexa, unspecified
0.016 0.984 0.000
K70.9 Alcoholic liver disease, unspecified
0.000 0.984 0.016
H57.8 Other specified disorders of eye and adnexa
0.015 0.985 0.000
H57 Other disorders of eye and adnexa
0.015 0.985 0.000
R40 Somnolence, stupor and coma
0.015 0.985 0.000
D46.4 Refractory anaemia, unspecified
0.000 0.985 0.014
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.000 0.986 0.014
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.986 0.014
D46.9 Myelodysplastic syndrome, unspecified
0.000 0.986 0.014
D44.3 Pituitary gland
0.000 0.986 0.014
E04.0 Non-toxic diffuse goitre
0.000 0.986 0.014
K70.0 Alcoholic fatty liver
0.000 0.987 0.013
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.987 0.013
K93.1 Megacolon in Chagas' disease
0.000 0.987 0.013
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.987 0.013
Z43.1 Attention to gastrostomy
0.000 0.987 0.013
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.000 0.987 0.013
D44.7 Aortic body and other paraganglia
0.000 0.987 0.013
D44.0 Thyroid gland
0.000 0.987 0.013
K70 Alcoholic liver disease
0.000 0.987 0.013
L40.5 Arthropathic psoriasis
0.013 0.987 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.987 0.013
H57.0 Anomalies of pupillary function
0.013 0.987 0.000
D39.7 Other female genital organs
0.000 0.987 0.013
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.987 0.013
D46.2 Refractory anaemia with excess of blasts
0.000 0.987 0.013
D46.1 Refractory anaemia with sideroblasts
0.000 0.987 0.013
D37.7 Other digestive organs
0.000 0.987 0.013
D39.0 Uterus
0.000 0.987 0.012
D37.3 Appendix
0.000 0.987 0.012
D39.9 Female genital organ, unspecified
0.000 0.988 0.012
D39.2 Placenta
0.000 0.988 0.012
D46.7 Other myelodysplastic syndromes
0.000 0.988 0.012
D44.6 Carotid body
0.000 0.988 0.012
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
0.000 0.988 0.012
D46.5 Refractory anaemia with multi-lineage dysplasia
0.000 0.988 0.012
D46.3 Refractory anaemia with excess of blasts with transformation
0.000 0.988 0.012
D46.0 Refractory anaemia without sideroblasts, so stated
0.000 0.988 0.012
D37.6 Liver, gallbladder and bile ducts
0.000 0.988 0.012
D44.5 Pineal gland
0.000 0.988 0.012
D44.2 Parathyroid gland
0.000 0.988 0.012
D47.2 Monoclonal gammopathy
0.000 0.988 0.012
H57.1 Ocular pain
0.012 0.988 0.000
D37.1 Stomach
0.000 0.989 0.011
D37.4 Colon
0.000 0.989 0.011
E55.9 Vitamin D deficiency, unspecified
0.002 0.989 0.009
D44.9 Endocrine gland, unspecified
0.000 0.989 0.011
D44.1 Adrenal gland
0.000 0.989 0.011
K70.4 Alcoholic hepatic failure
0.000 0.989 0.011
D37.9 Digestive organ, unspecified
0.000 0.989 0.011
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.000 0.989 0.010
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.000 0.989 0.010
D44.8 Pluriglandular involvement
0.000 0.989 0.010

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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