TreeWAS – Variant ID: rs9380173

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
E10.9 Without complications	0.000	0.230	0.770
E10 Insulin-dependent diabetes mellitus	0.000	0.276	0.724
E10.3 With ophthalmic complications	0.000	0.319	0.681
E10.5 With peripheral circulatory complications	0.000	0.367	0.632
N40 Hyperplasia of prostate	0.608	0.392	0.000
E10.1 With ketoacidosis	0.000	0.410	0.590
E10.0 With coma	0.000	0.446	0.554
E10.8 With unspecified complications	0.000	0.452	0.548
E10.7 With multiple complications	0.000	0.481	0.519
E10.6 With other specified complications	0.000	0.481	0.519
E10-E14 Diabetes mellitus	0.000	0.538	0.462
E10.4 With neurological complications	0.000	0.582	0.418
E14 Unspecified diabetes mellitus	0.000	0.617	0.383
O34.2 Maternal care due to uterine scar from previous surgery	0.000	0.620	0.380
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.000	0.622	0.378
O34 Maternal care for known or suspected abnormality of pelvic organs	0.000	0.624	0.376
O42 Premature rupture of membranes	0.000	0.635	0.365
E14.3 With ophthalmic complications	0.000	0.639	0.361
E13 Other specified diabetes mellitus	0.000	0.642	0.357
Chapter XV Pregnancy, childbirth and the puerperium	0.000	0.653	0.347
O60-O75 Complications of labour and delivery	0.000	0.653	0.347
O94-O99 Other obstetric conditions, not elsewhere classified	0.000	0.664	0.336
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.665	0.335
E12 Malnutrition-related diabetes mellitus	0.000	0.669	0.331
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.669	0.331
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.670	0.330
O63 Long labour	0.000	0.670	0.330
O48 Prolonged pregnancy	0.000	0.670	0.330
E10.2 With renal complications	0.001	0.673	0.326
O68 Labour and delivery complicated by foetal stress [distress]	0.000	0.681	0.319
O63.1 Prolonged second stage (of labour)	0.000	0.681	0.319
O43 Placental disorders	0.000	0.687	0.313
O69 Labour and delivery complicated by umbilical cord complications	0.000	0.687	0.313
E11 Non-insulin-dependent diabetes mellitus	0.000	0.687	0.313
O72 Postpartum haemorrhage	0.000	0.691	0.309
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.000	0.695	0.305
O32 Maternal care for known or suspected malpresentation of foetus	0.000	0.696	0.304
O35 Maternal care for known or suspected foetal abnormality and damage	0.000	0.698	0.301
O62 Abnormalities of forces of labour	0.000	0.701	0.299
O44 Placenta praevia	0.000	0.706	0.294
O75 Other complications of labour and delivery, not elsewhere classified	0.000	0.709	0.291
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.710	0.290
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.713	0.287
O69.2 Labour and delivery complicated by other cord entanglement	0.000	0.715	0.285
O72.1 Other immediate postpartum haemorrhage	0.000	0.715	0.285
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.000	0.715	0.285
E13.9 Without complications	0.000	0.717	0.283
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.720	0.280
O45 Premature separation of placenta [abruptio placentae]	0.000	0.720	0.279
O40 Polyhydramnios	0.000	0.722	0.278
O47 False labour	0.000	0.723	0.277
O34.8 Maternal care for other abnormalities of pelvic organs	0.000	0.724	0.276
E14.7 With multiple complications	0.000	0.725	0.275
E14.6 With other specified complications	0.000	0.725	0.275
E14.5 With peripheral circulatory complications	0.000	0.725	0.275
E14.4 With neurological complications	0.000	0.725	0.275
E14.2 Withrenal complications	0.000	0.725	0.275
E14.1 With ketoacidosis	0.000	0.725	0.275
E14.0 With coma	0.000	0.725	0.275
O34.3 Maternal care for cervical incompetence	0.000	0.726	0.274
E11.5 With peripheral circulatory complications	0.000	0.728	0.272
O34.7 Maternal care for abnormality of vulva and perineum	0.000	0.728	0.272
E11.4 With neurological complications	0.000	0.729	0.271
O31 Complications specific to multiple gestation	0.000	0.729	0.271
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.000	0.730	0.270
O34.6 Maternal care for abnormality of vagina	0.000	0.730	0.270
O34.5 Maternal care for other abnormalities of gravid uterus	0.000	0.730	0.270
O34.0 Maternal care for congenital malformation of uterus	0.000	0.730	0.270
O43.1 Malformation of placenta	0.000	0.731	0.269
O42.9 Premature rupture of membranes, unspecified	0.000	0.735	0.265
O33 Maternal care for known or suspected disproportion	0.000	0.736	0.264
O32.1 Maternal care for breech presentation	0.000	0.737	0.263
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.738	0.262
O75.2 Pyrexia during labour, not elsewhere classified	0.000	0.738	0.261
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.740	0.260
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.741	0.259
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.743	0.257
E13.8 With unspecified complications	0.000	0.743	0.256
E13.7 With multiple complications	0.000	0.743	0.256
E13.6 With other specified complications	0.000	0.743	0.256
E13.5 With peripheral circulatory complications	0.000	0.743	0.256
E13.4 With neurological complications	0.000	0.743	0.256
E13.3 With ophthalmic complications	0.000	0.743	0.256
E13.2 With renal complications	0.000	0.743	0.256
E13.1 With ketoacidosis	0.000	0.743	0.256
E13.0 With coma	0.000	0.743	0.256
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.744	0.255
E14.8 With unspecified complications	0.000	0.745	0.255
O32.2 Maternal care for transverse and oblique lie	0.000	0.746	0.254
O65 Obstructed labour due to maternal pelvic abnormality	0.000	0.748	0.252
O64 Obstructed labour due to malposition and malpresentation of foetus	0.000	0.750	0.250
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.000	0.751	0.249
O74 Complications of anaesthesia during labour and delivery	0.000	0.751	0.249
O60 Preterm delivery	0.000	0.751	0.249
O85-O92 Complications predominantly related to the puerperium	0.000	0.751	0.249
O30 Multiple gestation	0.000	0.753	0.247
O34.1 Maternal care for tumour of corpus uteri	0.000	0.753	0.247
O63.9 Long labour, unspecified	0.000	0.754	0.246
O62.0 Primary inadequate contractions	0.000	0.755	0.245
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.000	0.756	0.244
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.000	0.758	0.242
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.758	0.242
O97 Death from sequelae of direct obstetric causes	0.000	0.759	0.241
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.000	0.759	0.241
O95 Obstetric death of unspecified cause	0.000	0.759	0.241
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.000	0.759	0.241
O62.1 Secondary uterine inertia	0.000	0.759	0.241
O34.4 Maternal care for other abnormalities of cervix	0.000	0.761	0.239
E11.1 With ketoacidosis	0.000	0.761	0.239
O69.8 Labour and delivery complicated by other cord complications	0.000	0.761	0.239
O44.0 Placenta praevia specified as without haemorrhage	0.000	0.762	0.238
E11.3 With ophthalmic complications	0.000	0.762	0.238
E12.9 Without complications	0.000	0.762	0.238
E12.8 With unspecified complications	0.000	0.762	0.238
E12.7 With multiple complications	0.000	0.762	0.238
E12.6 With other specified complications	0.000	0.762	0.238
E12.5 With peripheral circulatory complications	0.000	0.762	0.238
E12.4 With neurological complications	0.000	0.762	0.238
E12.3 With ophthalmic complications	0.000	0.762	0.238
E12.2 With renal complications	0.000	0.762	0.238
E12.1 With ketoacidosis	0.000	0.762	0.238
E12.0 With coma	0.000	0.762	0.238
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.762	0.237
O63.2 Delayed delivery of second twin, triplet, etc.	0.000	0.763	0.237
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.763	0.236
O62.3 Precipitate labour	0.000	0.765	0.235
O47.9 False labour, unspecified	0.000	0.766	0.234
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.768	0.232
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.769	0.231
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.000	0.770	0.229
O66 Other obstructed labour	0.000	0.772	0.228
O72.0 Third-stage haemorrhage	0.000	0.772	0.228
O63.0 Prolonged first stage (of labour)	0.000	0.772	0.228
O32.3 Maternal care for face, brow and chin presentation	0.000	0.775	0.225
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.775	0.225
O43.9 Placental disorder, unspecified	0.000	0.775	0.225
O43.2 Morbidly adherent placenta	0.000	0.775	0.225
O43.0 Placental transfusion syndromes	0.000	0.775	0.225
O69.5 Labour and delivery complicated by vascular lesion of cord	0.000	0.775	0.224
O69.4 Labour and delivery complicated by vasa praevia	0.000	0.775	0.224
O69.3 Labour and delivery complicated by short cord	0.000	0.775	0.224
E11.7 With multiple complications	0.000	0.775	0.224
O72.3 Postpartum coagulation defects	0.000	0.779	0.221
O43.8 Other placental disorders	0.000	0.780	0.220
E11.8 With unspecified complications	0.000	0.782	0.218
O32.6 Maternal care for compound presentation	0.000	0.782	0.218
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.000	0.784	0.216
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.000	0.784	0.216
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.000	0.784	0.216
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.000	0.784	0.216
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.000	0.784	0.216
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.000	0.784	0.216
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.000	0.785	0.215
O62.9 Abnormality of forces of labour, unspecified	0.000	0.785	0.215
O62.8 Other abnormalities of forces of labour	0.000	0.785	0.215
O61 Failed induction of labour	0.000	0.786	0.214
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.789	0.211
K90 Intestinal malabsorption	0.000	0.789	0.211
O69.0 Labour and delivery complicated by prolapse of cord	0.000	0.789	0.211
O71 Other obstetric trauma	0.000	0.790	0.210
O20-O29 Other maternal disorders predominantly related to pregnancy	0.000	0.790	0.210
O32.4 Maternal care for high head at term	0.000	0.790	0.210
O45.9 Premature separation of placenta, unspecified	0.000	0.791	0.209
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.000	0.791	0.209
O75.9 Complication of labour and delivery, unspecified	0.000	0.791	0.208
O75.5 Delayed delivery after artificial rupture of membranes	0.000	0.791	0.208
O75.4 Other complications of obstetric surgery and procedures	0.000	0.791	0.208
O75.3 Other infection during labour	0.000	0.791	0.208
O75.1 Shock during or following labour and delivery	0.000	0.791	0.208
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.000	0.792	0.208
O32.9 Maternal care for malpresentation of foetus, unspecified	0.000	0.793	0.207
O44.1 Placenta praevia with haemorrhage	0.000	0.794	0.206
E11.0 With coma	0.000	0.795	0.205
O32.0 Maternal care for unstable lie	0.000	0.795	0.205
O45.8 Other premature separation of placenta	0.000	0.799	0.200
O45.0 Premature separation of placenta with coagulation defect	0.000	0.799	0.200
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.000	0.800	0.200
O72.2 Delayed and secondary postpartum haemorrhage	0.000	0.800	0.199
O20 Haemorrhage in early pregnancy	0.000	0.803	0.197
O75.8 Other specified complications of labour and delivery	0.000	0.803	0.197
O73 Retained placenta and membranes, without haemorrhage	0.000	0.804	0.196
O20.0 Threatened abortion	0.000	0.805	0.195
O31.8 Other complications specific to multiple gestation	0.000	0.806	0.194
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.000	0.806	0.194
O31.1 Continuing pregnancy after abortion of one foetus or more	0.000	0.806	0.194
O31.0 Papyraceous foetus	0.000	0.806	0.194
O75.0 Maternal distress during labour and delivery	0.000	0.810	0.190
O33.8 Maternal care for disproportion of other origin	0.000	0.810	0.189
O33.7 Maternal care for disproportion due to other foetal deformities	0.000	0.810	0.189
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.000	0.810	0.189
O33.5 Maternal care for disproportion due to unusually large foetus	0.000	0.810	0.189
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.000	0.810	0.189
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.000	0.810	0.189
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.000	0.810	0.189
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.000	0.810	0.189
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.000	0.810	0.189
E11.6 With other specified complications	0.000	0.811	0.188
O69.9 Labour and delivery complicated by cord complication, unspecified	0.000	0.813	0.187
O41 Other disorders of amniotic fluid and membranes	0.000	0.813	0.187
O85 Puerperal sepsis	0.000	0.813	0.187
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.814	0.186
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.000	0.814	0.186
O46.9 Antepartum haemorrhage, unspecified	0.000	0.815	0.185
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.000	0.816	0.184
O33.9 Maternal care for disproportion, unspecified	0.000	0.817	0.183
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.000	0.819	0.181
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.000	0.819	0.181
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.000	0.819	0.181
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.000	0.819	0.181
O65.2 Obstructed labour due to pelvic inlet contraction	0.000	0.819	0.181
O65.1 Obstructed labour due to generally contracted pelvis	0.000	0.819	0.181
O65.0 Obstructed labour due to deformed pelvis	0.000	0.819	0.181
O87 Venous complications in the puerperium	0.000	0.821	0.179
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.000	0.821	0.179
O64.5 Obstructed labour due to compound presentation	0.000	0.821	0.179
O64.4 Obstructed labour due to shoulder presentation	0.000	0.821	0.179
O64.3 Obstructed labour due to brow presentation	0.000	0.821	0.179
O64.2 Obstructed labour due to face presentation	0.000	0.821	0.179
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.000	0.821	0.179
O60.3 Preterm delivery without spontaneous labour	0.000	0.821	0.178
O60.2 Preterm spontaneous labour with term delivery	0.000	0.821	0.178
O60.1 Preterm spontaneous labour with preterm delivery	0.000	0.821	0.178
O60.0 Preterm labour without delivery	0.000	0.821	0.178
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.000	0.821	0.178
O74.8 Other complications of anaesthesia during labour and delivery	0.000	0.821	0.178
O74.7 Failed or difficult intubation during labour and delivery	0.000	0.821	0.178
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.000	0.821	0.178
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.000	0.821	0.178
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.000	0.821	0.178
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.000	0.821	0.178
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.000	0.821	0.178
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.000	0.821	0.178
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.000	0.821	0.178
O92 Other disorders of breast and lactation associated with childbirth	0.000	0.821	0.178
O91 Infections of breast associated with childbirth	0.000	0.821	0.178
O89 Complications of anaesthesia during the puerperium	0.000	0.821	0.178
O88 Obstetric embolism	0.000	0.821	0.178
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.000	0.822	0.178
O30.9 Multiple gestation, unspecified	0.000	0.822	0.177
O30.8 Other multiple gestation	0.000	0.822	0.177
O30.2 Quadruplet pregnancy	0.000	0.822	0.177
O30.1 Triplet pregnancy	0.000	0.822	0.177
O66.0 Obstructed labour due to shoulder dystocia	0.000	0.823	0.176
O90 Complications of the puerperium, not elsewhere classified	0.000	0.824	0.176
O62.2 Other uterine inertia	0.000	0.826	0.174
O64.1 Obstructed labour due to breech presentation	0.000	0.826	0.174
O96.9 Death from unspecified obstetric cause	0.000	0.827	0.173
O96.1 Death from indirect obstetric cause	0.000	0.827	0.173
O96.0 Death from direct obstetric cause	0.000	0.827	0.173
O97.9 Death from sequelae of obstetric cause, unspecified	0.000	0.827	0.173
O97.1 Death from sequelae of indirect obstetric cause	0.000	0.827	0.173
O97.0 Death from sequelae of direct obstetric cause	0.000	0.827	0.173
O86 Other puerperal infections	0.000	0.829	0.171
O46.0 Antepartum haemorrhage with coagulation defect	0.000	0.830	0.170
O32.8 Maternal care for other malpresentation of foetus	0.000	0.833	0.167
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.835	0.165
O24 Diabetes mellitus in pregnancy	0.000	0.836	0.164
O66.9 Obstructed labour, unspecified	0.000	0.836	0.164
O66.8 Other specified obstructed labour	0.000	0.836	0.164
O66.3 Obstructed labour due to other abnormalities of foetus	0.000	0.836	0.164
O66.2 Obstructed labour due to unusually large foetus	0.000	0.836	0.164
O66.1 Obstructed labour due to locked twins	0.000	0.836	0.164
O47.0 False labour before 37 completed weeks of gestation	0.000	0.838	0.162
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.000	0.838	0.161
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.838	0.161
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.000	0.838	0.161
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.000	0.838	0.161
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.000	0.838	0.161
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.000	0.838	0.161
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.000	0.838	0.161
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.000	0.838	0.161
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.000	0.838	0.161
O64.8 Obstructed labour due to other malposition and malpresentation	0.000	0.841	0.159
O30.0 Twin pregnancy	0.000	0.846	0.154
O61.8 Other failed induction of labour	0.000	0.846	0.154
O61.1 Failed instrumental induction of labour	0.000	0.846	0.154
O66.4 Failed trial of labour, unspecified	0.000	0.846	0.153
O71.4 Obstetric high vaginal laceration alone	0.000	0.847	0.153
E14.9 Without complications	0.000	0.848	0.152
K90.8 Other intestinal malabsorption	0.000	0.848	0.151
K90.3 Pancreatic steatorrhoea	0.000	0.848	0.151
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.848	0.151
K90.1 Tropical sprue	0.000	0.848	0.151
O71.9 Obstetric trauma, unspecified	0.000	0.849	0.151
O71.6 Obstetric damage to pelvic joints and ligaments	0.000	0.849	0.151
O71.5 Other obstetric injury to pelvic organs	0.000	0.849	0.151
O71.3 Obstetric laceration of cervix	0.000	0.849	0.151
O71.2 Postpartum inversion of uterus	0.000	0.849	0.151
O71.1 Rupture of uterus during labour	0.000	0.849	0.151
O71.0 Rupture of uterus before onset of labour	0.000	0.849	0.151
O29 Complications of anaesthesia during pregnancy	0.000	0.849	0.151
O25 Malnutrition in pregnancy	0.000	0.849	0.151
O67.8 Other intrapartum haemorrhage	0.000	0.850	0.149
O67.0 Intrapartum haemorrhage with coagulation defect	0.000	0.850	0.149
O22 Venous complications in pregnancy	0.000	0.850	0.149
O71.7 Obstetric haematoma of pelvis	0.000	0.852	0.147
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.000	0.855	0.145
O36 Maternal care for other known or suspected foetal problems	0.000	0.855	0.145
O61.9 Failed induction of labour, unspecified	0.000	0.861	0.139
O61.0 Failed medical induction of labour	0.000	0.862	0.138
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.862	0.138
O80-O84 Delivery	0.000	0.864	0.136
O28 Abnormal findings on antenatal screening of mother	0.000	0.864	0.135
E11.9 Without complications	0.000	0.865	0.135
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.000	0.866	0.134
O41.1 Infection of amniotic sac and membranes	0.000	0.866	0.134
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.868	0.132
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.000	0.869	0.131
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.870	0.130
O87.2 Haemorrhoids in the puerperium	0.000	0.870	0.130
O86.4 Pyrexia of unknown origin following delivery	0.000	0.870	0.130
E11.2 With renal complications	0.000	0.871	0.129
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.871	0.129
O87.9 Venous complication in the puerperium, unspecified	0.000	0.871	0.129
O87.8 Other venous complications in the puerperium	0.000	0.871	0.129
O87.3 Cerebral venous thrombosis in the puerperium	0.000	0.871	0.129
O87.1 Deep phlebothrombosis in the puerperium	0.000	0.871	0.129
O87.0 Superficial thrombophlebitis in the puerperium	0.000	0.871	0.129
O88.8 Other obstetric embolism	0.000	0.872	0.128
O88.3 Obstetric pyaemic and septic embolism	0.000	0.872	0.128
O88.2 Obstetric blood-clot embolism	0.000	0.872	0.128
O88.1 Amniotic fluid embolism	0.000	0.872	0.128
O88.0 Obstetric air embolism	0.000	0.872	0.128
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.000	0.872	0.128
O89.8 Other complications of anaesthesia during the puerperium	0.000	0.872	0.128
O89.6 Failed or difficult intubation during the puerperium	0.000	0.872	0.128
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.000	0.872	0.128
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.000	0.872	0.128
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.000	0.872	0.128
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.000	0.872	0.128
O89.1 Cardiac complications of anaesthesia during the puerperium	0.000	0.872	0.128
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.000	0.872	0.128
O91.2 Nonpurulent mastitis associated with childbirth	0.000	0.872	0.128
O91.1 Abscess of breast associated with childbirth	0.000	0.872	0.128
O91.0 Infection of nipple associated with childbirth	0.000	0.872	0.128
O92.7 Other and unspecified disorders of lactation	0.000	0.872	0.128
O92.6 Galactorrhoea	0.000	0.872	0.128
O92.5 Suppressed lactation	0.000	0.872	0.128
O92.4 Hypogalactia	0.000	0.872	0.128
O92.3 Agalactia	0.000	0.872	0.128
O92.2 Other and unspecified disorders of breast associated with childbirth	0.000	0.872	0.128
O92.1 Cracked nipple associated with childbirth	0.000	0.872	0.128
O92.0 Retracted nipple associated with childbirth	0.000	0.872	0.128
O90.9 Complication of the puerperium, unspecified	0.000	0.873	0.127
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.873	0.126
O90.5 Postpartum thyroiditis	0.000	0.874	0.126
O90.4 Postpartum acute renal failure	0.000	0.874	0.126
O90.3 Cardiomyopathy in the puerperium	0.000	0.874	0.126
O90.2 Haematoma of obstetric wound	0.000	0.874	0.126
O90.1 Disruption of perineal obstetric wound	0.000	0.874	0.126
O90.0 Disruption of Caesarean section wound	0.000	0.874	0.126
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.876	0.124
O86.8 Other specified puerperal infections	0.000	0.877	0.122
O86.3 Other genito-urinary tract infections following delivery	0.000	0.877	0.122
O86.2 Urinary tract infection following delivery	0.000	0.877	0.122
O90.8 Other complications of the puerperium, not elsewhere classified	0.000	0.878	0.122
O20.8 Other haemorrhage in early pregnancy	0.000	0.878	0.122
E05.9 Thyrotoxicosis, unspecified	0.000	0.879	0.121
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.879	0.121
O86.0 Infection of obstetric surgical wound	0.000	0.881	0.119
O15 Eclampsia	0.000	0.881	0.118
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.881	0.118
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.881	0.119
O24.3 Pre-existing diabetes mellitus, unspecified	0.000	0.882	0.118
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.000	0.882	0.118
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.000	0.882	0.118
O36.4 Maternal care for intra-uterine death	0.000	0.882	0.118
E00-E07 Disorders of thyroid gland	0.000	0.885	0.115
O71.8 Other specified obstetric trauma	0.000	0.885	0.114
O23 Infections of genito-urinary tract in pregnancy	0.000	0.886	0.114
O24.9 Diabetes mellitus in pregnancy, unspecified	0.000	0.886	0.114
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.000	0.888	0.112
O86.1 Other infection of genital tract following delivery	0.000	0.890	0.110
O67.9 Intrapartum haemorrhage, unspecified	0.000	0.891	0.109
O41.0 Oligohydramnios	0.000	0.891	0.108
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.000	0.891	0.108
O29.8 Other complications of anaesthesia during pregnancy	0.000	0.891	0.108
O29.6 Failed or difficult intubation during pregnancy	0.000	0.891	0.108
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.000	0.891	0.108
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.000	0.891	0.108
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.000	0.891	0.108
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.000	0.891	0.108
O29.1 Cardiac complications of anaesthesia during pregnancy	0.000	0.891	0.108
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.000	0.891	0.108
O22.9 Venous complication in pregnancy, unspecified	0.000	0.893	0.107
O22.8 Other venous complications in pregnancy	0.000	0.893	0.107
O22.5 Cerebral venous thrombosis in pregnancy	0.000	0.893	0.107
O22.3 Deep phlebothrombosis in pregnancy	0.000	0.893	0.107
O22.2 Superficial thrombophlebitis in pregnancy	0.000	0.893	0.107
O22.1 Genital varices in pregnancy	0.000	0.893	0.107
O22.0 Varicose veins of lower extremity in pregnancy	0.000	0.893	0.107
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.893	0.107
O46.8 Other antepartum haemorrhage	0.001	0.894	0.106
O22.4 Haemorrhoids in pregnancy	0.000	0.894	0.106
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.894	0.106
O12.0 Gestational oedema	0.000	0.894	0.106
O36.5 Maternal care for poor foetal growth	0.000	0.895	0.105
O73.0 Retained placenta, without haemorrhage	0.000	0.895	0.105
O82 Single delivery by Caesarean section	0.000	0.896	0.104
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.000	0.896	0.104
O36.2 Maternal care for hydrops foetalis	0.000	0.896	0.104
O36.1 Maternal care for other isoimmunisation	0.000	0.896	0.104
O36.3 Maternal care for signs of foetal hypoxia	0.000	0.896	0.104
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.898	0.102
O84 Multiple delivery	0.000	0.902	0.098
O83 Other assisted single delivery	0.000	0.902	0.098
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.000	0.902	0.097
O28.8 Other abnormal findings on antenatal screening of mother	0.000	0.902	0.097
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.000	0.902	0.097
O28.4 Abnormal radiological finding on antenatal screening of mother	0.000	0.902	0.097
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.000	0.902	0.097
O28.2 Abnormal cytological finding on antenatal screening of mother	0.000	0.902	0.097
O28.0 Abnormal haematological finding on antenatal screening of mother	0.000	0.902	0.097
O36.0 Maternal care for rhesus isoimmunisation	0.000	0.903	0.097
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.905	0.094
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.906	0.094
O12.2 Gestational oedema with proteinuria	0.000	0.907	0.093
O00-O08 Pregnancy with abortive outcome	0.000	0.907	0.093
O12.1 Gestational proteinuria	0.000	0.908	0.092
O36.9 Maternal care for foetal problem, unspecified	0.000	0.908	0.092
K90.9 Intestinal malabsorption, unspecified	0.001	0.909	0.090
O21 Excessive vomiting in pregnancy	0.000	0.911	0.088
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.912	0.088
E40-E46 Malnutrition	0.000	0.912	0.088
E50-E64 Other nutritional deficiencies	0.000	0.913	0.087
O82.9 Delivery by Caesarean section, unspecified	0.000	0.914	0.086
O15.9 Eclampsia, unspecified as to time period	0.000	0.915	0.085
O15.2 Eclampsia in the puerperium	0.000	0.915	0.085
O15.1 Eclampsia in labour	0.000	0.915	0.085
O15.0 Eclampsia in pregnancy	0.000	0.915	0.085
E05.5 Thyroid crisis or storm	0.000	0.915	0.085
E05.4 Thyrotoxicosis factitia	0.000	0.915	0.085
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.915	0.085
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.915	0.085
E05.8 Other thyrotoxicosis	0.000	0.915	0.085
O26 Maternal care for other conditions predominantly related to pregnancy	0.000	0.916	0.084
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.000	0.917	0.083
E03 Other hypothyroidism	0.000	0.917	0.083
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.917	0.083
E00 Congenital iodine-deficiency syndrome	0.000	0.917	0.083
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.917	0.083
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.000	0.918	0.082
O23.3 Infections of other parts of urinary tract in pregnancy	0.000	0.918	0.082
O23.2 Infections of urethra in pregnancy	0.000	0.918	0.082
O23.1 Infections of bladder in pregnancy	0.000	0.918	0.082
O23.0 Infections of kidney in pregnancy	0.000	0.918	0.082
O23.5 Infections of the genital tract in pregnancy	0.000	0.918	0.081
E07 Other disorders of thyroid	0.000	0.919	0.081
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.922	0.078
E53 Deficiency of other B group vitamins	0.000	0.922	0.078
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.924	0.076
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.924	0.076
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.924	0.076
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.924	0.076
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.000	0.924	0.076
O82.8 Other single delivery by Caesarean section	0.000	0.925	0.075
O82.2 Delivery by Caesarean hysterectomy	0.000	0.925	0.075
O82.0 Delivery by elective Caesarean section	0.000	0.926	0.074
E53.8 Deficiency of other specified B group vitamins	0.000	0.927	0.073
O81 Single delivery by forceps and vacuum extractor	0.000	0.928	0.071
O14.0 Moderate preeclampsia	0.000	0.929	0.071
O83.9 Assisted single delivery, unspecified	0.000	0.929	0.070
O83.8 Other specified assisted single delivery	0.000	0.929	0.070
O83.4 Destructive operation for delivery	0.000	0.929	0.070
O83.3 Delivery of viable foetus in abdominal pregnancy	0.000	0.929	0.070
O83.2 Other manipulation-assisted delivery	0.000	0.929	0.070
O83.1 Other assisted breech delivery	0.000	0.929	0.070
O83.0 Breech extraction	0.000	0.929	0.070
O84.9 Multiple delivery, unspecified	0.000	0.929	0.070
O84.8 Other multiple delivery	0.000	0.929	0.070
O84.2 Multiple delivery, all by Caesarean section	0.000	0.929	0.070
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.000	0.929	0.070
O84.0 Multiple delivery, all spontaneous	0.000	0.929	0.070
E65-E68 Obesity and other hyperalimentation	0.000	0.929	0.071
O36.6 Maternal care for excessive foetal growth	0.000	0.931	0.068
O82.1 Delivery by emergency Caesarean section	0.000	0.931	0.068
O14.2 HELLP syndrome	0.000	0.932	0.067
O08 Complications following abortion and ectopic and molar pregnancy	0.000	0.933	0.067
O07 Failed attempted abortion	0.000	0.933	0.067
O06 Unspecified abortion	0.000	0.933	0.067
O05 Other abortion	0.000	0.933	0.067
O01 Hydatidiform mole	0.000	0.933	0.067
E03.8 Other specified hypothyroidism	0.000	0.934	0.066
E16 Other disorders of pancreatic internal secretion	0.000	0.935	0.065
E07.8 Other specified disorders of thyroid	0.000	0.935	0.064
E46 Unspecified protein-energy malnutrition	0.000	0.936	0.064
O21.8 Other vomiting complicating pregnancy	0.000	0.936	0.063
O21.2 Late vomiting of pregnancy	0.000	0.936	0.063
O26.2 Pregnancy care of habitual aborter	0.000	0.936	0.064
E15 Nondiabetic hypoglycaemic coma	0.000	0.936	0.063
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.937	0.063
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.937	0.063
E45 Retarded development following protein-energy malnutrition	0.000	0.937	0.063
E43 Unspecified severe protein-energy malnutrition	0.000	0.937	0.063
E42 Marasmic kwashiorkor	0.000	0.937	0.063
E41 Nutritional marasmus	0.000	0.937	0.063
E40 Kwashiorkor	0.000	0.937	0.063
E04 Other non-toxic goitre	0.000	0.937	0.063
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.937	0.063

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations