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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9380240
log Bayes Factor = 54.5503
Chromosome 6   position 31,268,832  (GRCh37) Explore rs9380240 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.000 1.000
M45 Ankylosing spondylitis
0.000 0.004 0.996
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.014 0.986
K70 Alcoholic liver disease
0.000 0.039 0.961
K70-K77 Diseases of liver
0.000 0.042 0.958
K75 Other inflammatory liver diseases
0.000 0.048 0.952
L40.0 Psoriasis vulgaris
0.000 0.052 0.948
E03 Other hypothyroidism
0.000 0.062 0.938
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.063 0.937
G35 Multiple sclerosis
0.000 0.066 0.934
K70.9 Alcoholic liver disease, unspecified
0.000 0.072 0.928
K70.1 Alcoholic hepatitis
0.000 0.073 0.927
K75.8 Other specified inflammatory liver diseases
0.000 0.077 0.923
K75.4 Autoimmune hepatitis
0.000 0.080 0.920
K73 Chronic hepatitis, not elsewhere classified
0.000 0.089 0.911
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.125 0.874
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.129 0.871
G30-G32 Other degenerative diseases of the nervous system
0.000 0.134 0.866
K90 Intestinal malabsorption
0.000 0.140 0.860
Chapter VI Diseases of the nervous system
0.000 0.141 0.859
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.142 0.858
L40-L45 Papulosquamous disorders
0.000 0.144 0.856
K72 Hepatic failure, not elsewhere classified
0.000 0.150 0.850
D50-D53 Nutritional anaemias
0.000 0.152 0.848
K70.0 Alcoholic fatty liver
0.000 0.155 0.845
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.157 0.843
D50 Iron deficiency anaemia
0.000 0.158 0.842
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.159 0.841
E00-E07 Disorders of thyroid gland
0.000 0.162 0.838
K70.4 Alcoholic hepatic failure
0.000 0.168 0.832
K73.9 Chronic hepatitis, unspecified
0.000 0.169 0.831
Chapter XI Diseases of the digestive system
0.000 0.173 0.827
K90-K93 Other diseases of the digestive system
0.000 0.173 0.827
K75.0 Abscess of liver
0.000 0.174 0.826
D50.9 Iron deficiency anaemia, unspecified
0.000 0.174 0.826
# Top node
0.000 0.176 0.824
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.179 0.821
L40.1 Generalised pustular psoriasis
0.000 0.183 0.817
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.187 0.813
D52 Folate deficiency anaemia
0.000 0.188 0.812
D60-D64 Aplastic and other anaemias
0.000 0.188 0.812
D64 Other anaemias
0.000 0.191 0.809
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.195 0.805
D64.9 Anaemia, unspecified
0.000 0.196 0.804
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.197 0.803
D80-D89 Certain disorders involving the immune mechanism
0.000 0.208 0.792
G31.2 Degeneration of nervous system due to alcohol
0.000 0.210 0.790
D52.9 Folate deficiency anaemia, unspecified
0.000 0.213 0.787
G31.8 Other specified degenerative diseases of nervous system
0.000 0.217 0.783
E03.8 Other specified hypothyroidism
0.000 0.217 0.783
L50-L54 Urticaria and erythema
0.000 0.226 0.774
D50.8 Other iron deficiency anaemias
0.000 0.228 0.772
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.238 0.762
L40.3 Pustulosis palmaris et plantaris
0.000 0.239 0.760
Chapter XXII Codes for special purposes
0.000 0.241 0.759
G31.0 Circumscribed brain atrophy
0.000 0.241 0.759
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.243 0.757
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.259 0.741
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.000 0.261 0.739
L50 Urticaria
0.000 0.264 0.736
D86 Sarcoidosis
0.000 0.268 0.732
K72.9 Hepatic failure, unspecified
0.000 0.276 0.724
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.278 0.722
L40.8 Other psoriasis
0.000 0.279 0.721
K72.0 Acute and subacute hepatic failure
0.000 0.282 0.718
L40.2 Acrodermatitis continua
0.000 0.283 0.717
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.286 0.714
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.286 0.714
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.286 0.714
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.286 0.714
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.286 0.714
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.286 0.714
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.286 0.714
G30 Alzheimer's disease
0.000 0.291 0.708
K35-K38 Diseases of appendix
0.000 0.303 0.697
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.306 0.694
U89 Agent resistant to other and unspecified antibiotics
0.000 0.308 0.692
D64.8 Other specified anaemias
0.000 0.309 0.691
M07.3 Other psoriatic arthropathies
0.000 0.311 0.689
D51 Vitamin B12 deficiency anaemia
0.000 0.311 0.689
K77 Liver disorders in diseases classified elsewhere
0.000 0.313 0.687
L52 Erythema nodosum
0.000 0.315 0.685
G06 Intracranial and intraspinal abscess and granuloma
0.000 0.315 0.685
K75.2 Nonspecific reactive hepatitis
0.000 0.318 0.682
K75.1 Phlebitis of portal vein
0.000 0.318 0.682
U88 Agent resistant to multiple antibiotics
0.000 0.324 0.676
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.325 0.675
E03.5 Myxoedema coma
0.000 0.327 0.673
E03.4 Atrophy of thyroid (acquired)
0.000 0.327 0.673
E03.3 Postinfectious hypothyroidism
0.000 0.327 0.673
L10-L14 Bullous disorders
0.000 0.330 0.670
D86.0 Sarcoidosis of lung
0.000 0.331 0.669
L40.4 Guttate psoriasis
0.000 0.338 0.662
E50-E64 Other nutritional deficiencies
0.000 0.342 0.658
U89.8 Agent resistant to other single specified antibiotic
0.000 0.344 0.656
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.347 0.653
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.347 0.653
G83 Other paralytic syndromes
0.000 0.347 0.653
D80 Immunodeficiency with predominantly antibody defects
0.000 0.350 0.650
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.355 0.644
D86.3 Sarcoidosis of skin
0.000 0.356 0.644
L50.1 Idiopathic urticaria
0.000 0.361 0.639
L50.0 Allergic urticaria
0.000 0.365 0.635
K38 Other diseases of appendix
0.000 0.365 0.635
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.366 0.634
G09 Sequelae of inflammatory diseases of central nervous system
0.000 0.369 0.631
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.375 0.625
E53 Deficiency of other B group vitamins
0.000 0.376 0.624
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.378 0.622
E03.1 Congenital hypothyroidism without goitre
0.000 0.378 0.621
E07 Other disorders of thyroid
0.000 0.380 0.620
M07 Psoriatic and enteropathic arthropathies
0.000 0.380 0.620
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.383 0.617
K90.3 Pancreatic steatorrhoea
0.000 0.383 0.617
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.383 0.617
K90.1 Tropical sprue
0.000 0.383 0.617
L44 Other papulosquamous disorders
0.000 0.386 0.614
L41 Parapsoriasis
0.000 0.386 0.614
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.386 0.614
G30.9 Alzheimer's disease, unspecified
0.000 0.387 0.613
G03 Meningitis due to other and unspecified causes
0.000 0.389 0.611
M45-M49 Spondylopathies
0.000 0.392 0.608
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.396 0.604
E53.8 Deficiency of other specified B group vitamins
0.000 0.396 0.604
D50.1 Sideropenic dysphagia
0.000 0.396 0.603
K70.3 Alcoholic cirrhosis of liver
0.000 0.397 0.603
D86.1 Sarcoidosis of lymph nodes
0.000 0.398 0.602
L50.9 Urticaria, unspecified
0.000 0.398 0.602
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.399 0.601
E00 Congenital iodine-deficiency syndrome
0.000 0.399 0.601
G06.0 Intracranial abscess and granuloma
0.000 0.407 0.593
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.407 0.593
D53 Other nutritional anaemias
0.000 0.413 0.587
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.413 0.587
D61 Other aplastic anaemias
0.000 0.415 0.585
K38.8 Other specified diseases of appendix
0.000 0.416 0.584
D52.8 Other folate deficiency anaemias
0.000 0.417 0.582
D52.1 Drug-induced folate deficiency anaemia
0.000 0.417 0.582
D52.0 Dietary folate deficiency anaemia
0.000 0.417 0.582
G70-G73 Diseases of myoneural junction and muscle
0.000 0.418 0.582
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.418 0.582
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.419 0.581
G83.4 Cauda equina syndrome
0.000 0.419 0.580
D64.4 Congenital dyserythropoietic anaemia
0.000 0.420 0.580
D64.3 Other sideroblastic anaemias
0.000 0.420 0.580
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.420 0.580
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.420 0.580
D64.0 Hereditary sideroblastic anaemia
0.000 0.420 0.580
K72.1 Chronic hepatic failure
0.000 0.422 0.577
D83 Common variable immunodeficiency
0.000 0.423 0.577
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.424 0.576
G06.1 Intraspinal abscess and granuloma
0.000 0.425 0.575
L13 Other bullous disorders
0.000 0.425 0.575
L42 Pityriasis rosea
0.000 0.425 0.575
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.425 0.575
G00 Bacterial meningitis, not elsewhere classified
0.000 0.428 0.572
M05-M14 Inflammatory polyarthropathies
0.000 0.428 0.572
G83.9 Paralytic syndrome, unspecified
0.000 0.431 0.569
D81 Combined immunodeficiencies
0.000 0.432 0.568
E05.9 Thyrotoxicosis, unspecified
0.000 0.432 0.568
D84 Other immunodeficiencies
0.000 0.434 0.566
K90.8 Other intestinal malabsorption
0.000 0.440 0.560
K36 Other appendicitis
0.000 0.442 0.558
G36 Other acute disseminated demyelination
0.000 0.444 0.556
L54 Erythema in diseases classified elsewhere
0.000 0.445 0.555
E07.8 Other specified disorders of thyroid
0.000 0.449 0.551
D86.9 Sarcoidosis, unspecified
0.000 0.451 0.549
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.451 0.549
L50.8 Other urticaria
0.000 0.452 0.548
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.000 0.453 0.547
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.000 0.454 0.546
E05.5 Thyroid crisis or storm
0.000 0.457 0.543
E05.4 Thyrotoxicosis factitia
0.000 0.457 0.543
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.457 0.543
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.457 0.543
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.467 0.533
U84 Resistance to other antimicrobial drugs
0.000 0.470 0.530
U83 Resistance to other antibiotics
0.000 0.470 0.530
U82 Resistance to betalactam antibiotics
0.000 0.470 0.530
U85 Resistance to antineoplastic drugs
0.000 0.470 0.530
G81 Hemiplegia
0.000 0.471 0.529
G80 Infantile cerebral palsy
0.000 0.471 0.529
K38.9 Disease of appendix, unspecified
0.000 0.472 0.528
L50.6 Contact urticaria
0.000 0.472 0.528
L50.5 Cholinergic urticaria
0.000 0.472 0.528
L50.4 Vibratory urticaria
0.000 0.472 0.528
L50.3 Dermatographic urticaria
0.000 0.472 0.528
L50.2 Urticaria due to cold and heat
0.000 0.472 0.528
E20-E35 Disorders of other endocrine glands
0.000 0.474 0.526
G04 Encephalitis, myelitis and encephalomyelitis
0.000 0.481 0.519
L53 Other erythematous conditions
0.000 0.485 0.515
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.485 0.515
G30.8 Other Alzheimer's disease
0.000 0.487 0.513
D82 Immunodeficiency associated with other major defects
0.000 0.488 0.512
E27 Other disorders of adrenal gland
0.000 0.489 0.511
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.490 0.510
L11 Other acantholytic disorders
0.000 0.491 0.509
Chapter I Certain infectious and parasitic diseases
0.000 0.491 0.509
G30.1 Alzheimer's disease with late onset
0.000 0.492 0.508
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.492 0.508
L13.0 Dermatitis herpetiformis
0.000 0.493 0.507
U89.9 Agent resistant to unspecified antibiotic
0.000 0.495 0.505
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.495 0.504
E27.1 Primary adrenocortical insufficiency
0.000 0.496 0.504
G03.9 Meningitis, unspecified
0.000 0.496 0.504
K71 Toxic liver disease
0.001 0.496 0.503
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.000 0.497 0.503
D61.9 Aplastic anaemia, unspecified
0.000 0.502 0.498
M00-M03 Infectious arthropathies
0.000 0.503 0.497
D55-D59 Haemolytic anaemias
0.000 0.504 0.495
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.000 0.505 0.495
M07.38 Other psoriatic arthropathies (Other)
0.000 0.506 0.494
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.506 0.494
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.506 0.494
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.506 0.494
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.506 0.494
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.506 0.494
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.506 0.494
D51.2 Transcobalamin II deficiency
0.000 0.506 0.494
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.506 0.494
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.507 0.493
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.507 0.493
G71 Primary disorders of muscles
0.000 0.507 0.493
G83.1 Monoplegia of lower limb
0.000 0.510 0.490
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.511 0.489
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.512 0.488
G01 Meningitis in bacterial diseases classified elsewhere
0.000 0.513 0.487
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.518 0.482
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.518 0.481
L14 Bullous disorders in diseases classified elsewhere
0.000 0.520 0.480
G06.2 Extradural and subdural abscess, unspecified
0.000 0.521 0.479
E58 Dietary calcium deficiency
0.000 0.523 0.477
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.525 0.475
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.528 0.472
E63 Other nutritional deficiencies
0.000 0.528 0.472
E50 Vitamin A deficiency
0.000 0.528 0.472
E60 Dietary zinc deficiency
0.000 0.528 0.472
E59 Dietary selenium deficiency
0.000 0.528 0.472
E52 Niacin deficiency [pellagra]
0.000 0.528 0.472
G83.8 Other specified paralytic syndromes
0.000 0.528 0.472
E55 Vitamin D deficiency
0.000 0.529 0.471
E56 Other vitamin deficiencies
0.000 0.529 0.471
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.531 0.469
E51 Thiamine deficiency
0.000 0.531 0.469
G83.5 Locked-in syndrome
0.000 0.532 0.468
G83.3 Monoplegia, unspecified
0.000 0.532 0.468
G83.0 Diplegia of upper limbs
0.000 0.532 0.468
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.532 0.468
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.534 0.466
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.534 0.466
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.534 0.466
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.534 0.466
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.534 0.466
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.534 0.466
B07 Viral warts
0.000 0.534 0.466
L10 Pemphigus
0.000 0.534 0.466
G30.0 Alzheimer's disease with early onset
0.000 0.534 0.466
E27.2 Addisonian crisis
0.000 0.535 0.465
D84.9 Immunodeficiency, unspecified
0.000 0.538 0.461
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.541 0.459
E20 Hypoparathyroidism
0.000 0.545 0.455
K38.3 Fistula of appendix
0.000 0.545 0.455
K38.2 Diverticulum of appendix
0.000 0.545 0.455
K38.0 Hyperplasia of appendix
0.000 0.545 0.455
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.000 0.545 0.454
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.000 0.546 0.454
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.547 0.453
E40-E46 Malnutrition
0.000 0.547 0.452
E53.1 Pyridoxine deficiency
0.000 0.552 0.448
E53.0 Riboflavin deficiency
0.000 0.552 0.448
E07.1 Dyshormogenetic goitre
0.000 0.555 0.445
E07.0 Hypersecretion of calcitonin
0.000 0.555 0.445
M07.5 Arthropathy in ulcerative colitis
0.000 0.555 0.444
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.555 0.444
M07.2 Psoriatic spondylitis
0.000 0.555 0.444
M07.1 Arthritis mutilans
0.000 0.555 0.444
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.555 0.444
K74 Fibrosis and cirrhosis of liver
0.000 0.556 0.444
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.557 0.442
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.558 0.442
D89.3 Immune reconstitution syndrome
0.000 0.558 0.442
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.558 0.442
G00.1 Pneumococcal meningitis
0.000 0.559 0.441
L41.9 Parapsoriasis, unspecified
0.000 0.560 0.440
L41.8 Other parapsoriasis
0.000 0.560 0.440
L41.5 Retiform parapsoriasis
0.000 0.560 0.440
L41.4 Large plaque parapsoriasis
0.000 0.560 0.440
L41.3 Small plaque parapsoriasis
0.000 0.560 0.440
L41.2 Lymphomatoid papulosis
0.000 0.560 0.440
L41.1 Pityriasis lichenoides chronica
0.000 0.560 0.440
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.560 0.440
L44.9 Papulosquamous disorder, unspecified
0.000 0.560 0.440
L44.8 Other specified papulosquamous disorders
0.000 0.560 0.440
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.560 0.440
L44.3 Lichen ruber moniliformis
0.000 0.560 0.440
L44.2 Lichen striatus
0.000 0.560 0.440
L44.1 Lichen nitidus
0.000 0.560 0.440
L44.0 Pityriasis rubra pilaris
0.000 0.560 0.440
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.560 0.440
G71.3 Mitochondrial myopathy, not elsewhere classified
0.000 0.560 0.439
B35-B49 Mycoses
0.000 0.561 0.439
G03.8 Meningitis due to other specified causes
0.000 0.561 0.438
G03.2 Benign recurrent meningitis [Mollaret]
0.000 0.561 0.438
G03.1 Chronic meningitis
0.000 0.561 0.438
G03.0 Nonpyogenic meningitis
0.000 0.561 0.438
M07.6 Other enteropathic arthropathies
0.000 0.562 0.438
E06 Thyroiditis
0.000 0.564 0.435
L12 Pemphigoid
0.000 0.567 0.433
K37 Unspecified appendicitis
0.000 0.569 0.431
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.569 0.431
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.569 0.431
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.569 0.431
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.569 0.431
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.569 0.431
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.569 0.431
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.569 0.431
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.569 0.431
D89.1 Cryoglobulinaemia
0.000 0.572 0.428
B00 Herpesviral [herpes simplex] infections
0.000 0.574 0.426
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.000 0.574 0.426
B37 Candidiasis
0.000 0.574 0.426
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.575 0.425
K93.1 Megacolon in Chagas' disease
0.000 0.575 0.425
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.575 0.425
D83.9 Common variable immunodeficiency, unspecified
0.000 0.577 0.423
D53.8 Other specified nutritional anaemias
0.000 0.579 0.421
D53.2 Scorbutic anaemia
0.000 0.579 0.421
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.579 0.421
D53.0 Protein deficiency anaemia
0.000 0.579 0.421
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.579 0.421
D61.8 Other specified aplastic anaemias
0.000 0.581 0.419
D61.3 Idiopathic aplastic anaemia
0.000 0.581 0.419
D61.2 Aplastic anaemia due to other external agents
0.000 0.581 0.419
E53.9 Vitamin B deficiency, unspecified
0.000 0.581 0.419
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.000 0.582 0.418
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.000 0.582 0.418
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.583 0.417
D60.8 Other acquired pure red cell aplasias
0.000 0.583 0.417
D60.1 Transient acquired pure red cell aplasia
0.000 0.583 0.417
D60.0 Chronic acquired pure red cell aplasia
0.000 0.583 0.417
G81.1 Spastic hemiplegia
0.000 0.584 0.416
D83.8 Other common variable immunodeficiencies
0.000 0.586 0.414
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.586 0.414
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.586 0.414
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.586 0.414
P90-P96 Other disorders originating in the perinatal period
0.000 0.587 0.413
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.000 0.587 0.413
P75-P78 Digestive system disorders of fetus and newborn
0.000 0.587 0.413
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.000 0.587 0.413
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.000 0.587 0.413
P35-P39 Infections specific to the perinatal period
0.000 0.587 0.413
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.000 0.587 0.413
P05-P08 Disorders related to length of gestation and fetal growth
0.000 0.587 0.413
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.000 0.587 0.413
L13.9 Bullous disorder, unspecified
0.000 0.587 0.412
L13.8 Other specified bullous disorders
0.000 0.587 0.412
L13.1 Subcorneal pustular dermatitis
0.000 0.587 0.412
G00.8 Other bacterial meningitis
0.000 0.589 0.410
G00.3 Staphylococcal meningitis
0.000 0.589 0.410
G00.2 Streptococcal meningitis
0.000 0.589 0.410
G00.0 Haemophilus meningitis
0.000 0.589 0.410
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.590 0.410
D81.9 Combined immunodeficiency, unspecified
0.000 0.592 0.407
D81.8 Other combined immunodeficiencies
0.000 0.592 0.407
D81.7 Major histocompatibility complex class II deficiency
0.000 0.592 0.407
D81.6 Major histocompatibility complex class I deficiency
0.000 0.592 0.407
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.592 0.407
D81.4 Nezelof's syndrome
0.000 0.592 0.407
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.592 0.407
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.592 0.407
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.592 0.407
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.592 0.407
M00 Pyogenic arthritis
0.000 0.593 0.407
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.594 0.406
L53.0 Toxic erythema
0.000 0.594 0.405
G00.9 Bacterial meningitis, unspecified
0.000 0.595 0.405
E20.9 Hypoparathyroidism, unspecified
0.000 0.595 0.405
E25 Adrenogenital disorders
0.000 0.595 0.405
B37.8 Candidiasis of other sites
0.000 0.595 0.405
G80.0 Spastic cerebral palsy
0.000 0.596 0.404
K90.9 Intestinal malabsorption, unspecified
0.000 0.598 0.402
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.598 0.402
E28 Ovarian dysfunction
0.000 0.598 0.401
M40-M43 Deforming dorsopathies
0.000 0.599 0.401
G70 Myasthenia gravis and other myoneural disorders
0.000 0.600 0.400
D53.9 Nutritional anaemia, unspecified
0.000 0.600 0.399
B02 Zoster [herpes zoster]
0.000 0.601 0.399
G36.9 Acute disseminated demyelination, unspecified
0.000 0.601 0.399
G36.8 Other specified acute disseminated demyelination
0.000 0.601 0.399
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.601 0.399
K74.0 Hepatic fibrosis
0.000 0.601 0.399
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.601 0.399
B24 Unspecified human immunodeficiency virus [HIV] disease
0.000 0.601 0.398
P10-P15 Birth trauma
0.000 0.602 0.398
L54.8 Erythema in other diseases classified elsewhere
0.000 0.602 0.398
L54.0 Erythema marginatum in acute rheumatic fever
0.000 0.602 0.398
D84.1 Defects in the complement system
0.000 0.602 0.398
M02 Reactive arthropathies
0.000 0.603 0.397
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.000 0.606 0.394
L11.0 Acquired keratosis follicularis
0.000 0.607 0.393
G82 Paraplegia and tetraplegia
0.000 0.607 0.393
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.000 0.607 0.392
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.000 0.607 0.392
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.000 0.607 0.392
M10 Gout
0.000 0.607 0.392
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.610 0.390
M95.0 Acquired deformity of nose
0.000 0.611 0.389
B01 Varicella [chickenpox]
0.000 0.613 0.387
B95-B98 Bacterial, viral and other infectious agents
0.000 0.614 0.386
E24 Cushing's syndrome
0.000 0.614 0.386
K35 Acute appendicitis
0.000 0.614 0.386
B97 Viral agents as the cause of diseases classified to other chapters
0.000 0.615 0.385
G71.1 Myotonic disorders
0.000 0.617 0.383
G80.9 Infantile cerebral palsy, unspecified
0.000 0.617 0.383
M12 Other specific arthropathies
0.000 0.617 0.383
M08 Juvenile arthritis
0.000 0.618 0.381
K35.8 Acute appendicitis, other and unspecified
0.000 0.618 0.382
E54 Ascorbic acid deficiency
0.000 0.619 0.381
U82.9 Resistance to betalactam antibiotics, unspecified
0.000 0.620 0.380
U82.8 Resistance to other betalactam antibiotics
0.000 0.620 0.380
U82.2 Extended spectrum betalactamase (ESBL) resistance
0.000 0.620 0.380
U82.1 Resistance to methicillin
0.000 0.620 0.380
U82.0 Resistance to penicillin
0.000 0.620 0.380
U83.9 Resistance to unspecified antibiotic
0.000 0.620 0.380
U83.8 Resistance to other single specified antibiotic
0.000 0.620 0.380
U83.7 Resistance to multiple antibiotics
0.000 0.620 0.380
U83.2 Resistance to quinolones
0.000 0.620 0.380
U83.1 Resistance to other vancomycin related antibiotics
0.000 0.620 0.380
U83.0 Resistance to vancomycin
0.000 0.620 0.380
U84.9 Resistance to unspecified antimicrobial drugs
0.000 0.620 0.380
U84.8 Resistance to other specified antimicrobial drug
0.000 0.620 0.380
U84.7 Resistance to multiple antimicrobial drugs
0.000 0.620 0.380
U84.3 Resistance to tuberculostatic drug(s)
0.000 0.620 0.380
U84.2 Resistance to antiviral drug(s)
0.000 0.620 0.380
U84.1 Resistance to antifungal drug(s)
0.000 0.620 0.380
U84.0 Resistance to antiparasitic drug(s)
0.000 0.620 0.380
G81.0 Flaccid hemiplegia
0.000 0.620 0.379
G80.8 Other infantile cerebral palsy
0.000 0.621 0.379
G80.4 Ataxic cerebral palsy
0.000 0.621 0.379
G80.3 Dyskinetic cerebral palsy
0.000 0.621 0.379
G80.2 Infantile hemiplegia
0.000 0.621 0.379
M49 Spondylopathies in diseases classified elsewhere
0.000 0.621 0.379
D59 Acquired haemolytic anaemia
0.000 0.622 0.377
M46 Other inflammatory spondylopathies
0.000 0.622 0.377
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.623 0.377
E32 Diseases of thymus
0.000 0.623 0.377
E31 Polyglandular dysfunction
0.000 0.623 0.377
E30 Disorders of puberty, not elsewhere classified
0.000 0.623 0.377
L51 Erythema multiforme
0.000 0.623 0.376
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.625 0.375
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.000 0.628 0.372
G04.1 Tropical spastic paraplegia
0.000 0.628 0.372
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.000 0.629 0.371
L53.3 Other chronic figurate erythema
0.000 0.630 0.369
L53.2 Erythema marginatum
0.000 0.630 0.369
L53.1 Erythema annulare centrifugum
0.000 0.630 0.369
B35 Dermatophytosis
0.000 0.631 0.369
A65-A69 Other spirochaetal diseases
0.000 0.631 0.368
D61.1 Drug-induced aplastic anaemia
0.000 0.632 0.368
K38.1 Appendicular concretions
0.000 0.632 0.368
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.632 0.367
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.632 0.367
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.632 0.367
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.632 0.367
D82.2 Immunodeficiency with short-limbed stature
0.000 0.632 0.367
D82.0 Wiskott-Aldrich syndrome
0.000 0.632 0.367
E27.5 Adrenomedullary hyperfunction
0.000 0.634 0.366
E27.0 Other adrenocortical overactivity
0.000 0.634 0.366
L11.9 Acantholytic disorder, unspecified
0.000 0.635 0.365
L11.8 Other specified acantholytic disorders
0.000 0.635 0.365
L11.1 Transient acantholytic dermatosis [Grover]
0.000 0.635 0.365
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.635 0.365
A75-A79 Rickettsioses
0.000 0.635 0.365
A70-A74 Other diseases caused by chlamydiae
0.000 0.635 0.365
A20-A28 Certain zoonotic bacterial diseases
0.000 0.635 0.365
B00.5 Herpesviral ocular disease
0.000 0.636 0.364
E28.3 Primary ovarian failure
0.000 0.636 0.364
K71.9 Toxic liver disease, unspecified
0.001 0.639 0.361
K71.8 Toxic liver disease with other disorders of liver
0.001 0.639 0.361
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.001 0.639 0.361
K71.5 Toxic liver disease with chronic active hepatitis
0.001 0.639 0.361
K71.4 Toxic liver disease with chronic lobular hepatitis
0.001 0.639 0.361
K71.3 Toxic liver disease with chronic persistent hepatitis
0.001 0.639 0.361
K71.2 Toxic liver disease with acute hepatitis
0.001 0.639 0.361
K71.0 Toxic liver disease with cholestasis
0.001 0.639 0.361
G37 Other demyelinating diseases of central nervous system
0.000 0.640 0.360
M43 Other deforming dorsopathies
0.000 0.640 0.360
G80.1 Spastic diplegia
0.000 0.640 0.360
M11 Other crystal arthropathies
0.000 0.641 0.359
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.000 0.643 0.357
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.000 0.643 0.357
E06.3 Autoimmune thyroiditis
0.000 0.644 0.356
D55 Anaemia due to enzyme disorders
0.000 0.644 0.355
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.645 0.355
B06 Rubella [German measles]
0.000 0.645 0.355

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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