TreeWAS – Variant ID: rs9380350

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.9 Without complications	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
E10.3 With ophthalmic complications	0.000	0.001	0.999
E10-E14 Diabetes mellitus	0.000	0.002	0.998
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.008	0.992
E00-E07 Disorders of thyroid gland	0.000	0.016	0.984
E10.1 With ketoacidosis	0.000	0.016	0.984
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.023	0.977
E16 Other disorders of pancreatic internal secretion	0.000	0.033	0.967
E16.2 Hypoglycaemia, unspecified	0.000	0.039	0.961
E06 Thyroiditis	0.000	0.055	0.945
E10.5 With peripheral circulatory complications	0.000	0.057	0.943
E04 Other non-toxic goitre	0.000	0.058	0.942
E11 Non-insulin-dependent diabetes mellitus	0.000	0.068	0.932
E03 Other hypothyroidism	0.000	0.068	0.932
E50-E64 Other nutritional deficiencies	0.000	0.081	0.919
E10.2 With renal complications	0.000	0.090	0.910
E06.3 Autoimmune thyroiditis	0.000	0.095	0.905
E03.9 Hypothyroidism, unspecified	0.000	0.097	0.903
E11.4 With neurological complications	0.000	0.121	0.879
E04.2 Non-toxic multinodular goitre	0.000	0.123	0.877
E04.1 Non-toxic single thyroid nodule	0.000	0.148	0.852
E11.1 With ketoacidosis	0.000	0.151	0.849
E10.6 With other specified complications	0.000	0.153	0.847
E55 Vitamin D deficiency	0.000	0.163	0.837
E10.4 With neurological complications	0.000	0.165	0.835
E53 Deficiency of other B group vitamins	0.000	0.168	0.832
E14 Unspecified diabetes mellitus	0.000	0.175	0.825
E11.3 With ophthalmic complications	0.000	0.193	0.807
E53.8 Deficiency of other specified B group vitamins	0.000	0.213	0.787
E55.9 Vitamin D deficiency, unspecified	0.000	0.222	0.778
E14.3 With ophthalmic complications	0.000	0.238	0.762
E06.9 Thyroiditis, unspecified	0.000	0.249	0.751
E10.0 With coma	0.000	0.250	0.750
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.261	0.739
E04.0 Non-toxic diffuse goitre	0.000	0.264	0.736
E11.2 With renal complications	0.000	0.271	0.729
E11.6 With other specified complications	0.000	0.274	0.726
E10.8 With unspecified complications	0.000	0.280	0.720
E10.7 With multiple complications	0.000	0.283	0.717
E12 Malnutrition-related diabetes mellitus	0.000	0.284	0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.294	0.706
E00 Congenital iodine-deficiency syndrome	0.000	0.294	0.706
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.294	0.706
E15 Nondiabetic hypoglycaemic coma	0.000	0.299	0.701
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.303	0.697
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.307	0.693
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.307	0.693
E16.4 Abnormal secretion of gastrin	0.000	0.307	0.693
E16.3 Increased secretion of glucagon	0.000	0.307	0.693
E06.5 Other chronic thyroiditis	0.000	0.323	0.677
E06.4 Drug-induced thyroiditis	0.000	0.323	0.677
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.323	0.677
E06.1 Subacute thyroiditis	0.000	0.323	0.677
E06.0 Acute thyroiditis	0.000	0.323	0.677
E04.8 Other specified non-toxic goitre	0.000	0.324	0.676
E11.7 With multiple complications	0.000	0.332	0.668
E03.5 Myxoedema coma	0.000	0.332	0.668
E03.4 Atrophy of thyroid (acquired)	0.000	0.332	0.668
E03.3 Postinfectious hypothyroidism	0.000	0.332	0.668
E03.1 Congenital hypothyroidism without goitre	0.000	0.332	0.668
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.332	0.668
E20-E35 Disorders of other endocrine glands	0.000	0.337	0.663
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.341	0.659
E63 Other nutritional deficiencies	0.000	0.341	0.659
E56 Other vitamin deficiencies	0.000	0.341	0.659
E50 Vitamin A deficiency	0.000	0.341	0.659
E60 Dietary zinc deficiency	0.000	0.341	0.659
E59 Dietary selenium deficiency	0.000	0.341	0.659
E58 Dietary calcium deficiency	0.000	0.341	0.659
E54 Ascorbic acid deficiency	0.000	0.341	0.659
E52 Niacin deficiency [pellagra]	0.000	0.341	0.659
E11.8 With unspecified complications	0.000	0.348	0.651
E16.1 Other hypoglycaemia	0.000	0.359	0.640
E51 Thiamine deficiency	0.000	0.373	0.627
E11.0 With coma	0.000	0.377	0.623
E20 Hypoparathyroidism	0.000	0.392	0.608
E55.0 Rickets, active	0.000	0.400	0.600
E53.1 Pyridoxine deficiency	0.000	0.404	0.596
E53.0 Riboflavin deficiency	0.000	0.404	0.596
E14.8 With unspecified complications	0.000	0.404	0.596
E14.7 With multiple complications	0.000	0.408	0.592
E14.6 With other specified complications	0.000	0.408	0.592
E14.5 With peripheral circulatory complications	0.000	0.408	0.592
E14.2 Withrenal complications	0.000	0.408	0.592
E14.0 With coma	0.000	0.408	0.592
E14.1 With ketoacidosis	0.000	0.411	0.589
E20.9 Hypoparathyroidism, unspecified	0.000	0.432	0.568
E27 Other disorders of adrenal gland	0.000	0.433	0.567
E14.4 With neurological complications	0.000	0.436	0.563
E27.1 Primary adrenocortical insufficiency	0.000	0.455	0.545
E13 Other specified diabetes mellitus	0.001	0.479	0.521
E65-E68 Obesity and other hyperalimentation	0.000	0.485	0.515
E12.9 Without complications	0.000	0.487	0.513
E12.8 With unspecified complications	0.000	0.487	0.513
E12.7 With multiple complications	0.000	0.487	0.513
E12.6 With other specified complications	0.000	0.487	0.513
E12.5 With peripheral circulatory complications	0.000	0.487	0.513
E12.4 With neurological complications	0.000	0.487	0.513
E12.3 With ophthalmic complications	0.000	0.487	0.513
E12.2 With renal complications	0.000	0.487	0.513
E12.1 With ketoacidosis	0.000	0.487	0.513
E12.0 With coma	0.000	0.487	0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.494	0.506
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.494	0.506
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.494	0.506
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.494	0.506
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.494	0.506
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.494	0.506
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.494	0.506
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.494	0.506
E40-E46 Malnutrition	0.001	0.498	0.502
E53.9 Vitamin B deficiency, unspecified	0.000	0.499	0.501
E61 Deficiency of other nutrient elements	0.000	0.512	0.488
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.524	0.476
E32 Diseases of thymus	0.000	0.524	0.476
E31 Polyglandular dysfunction	0.000	0.524	0.476
E30 Disorders of puberty, not elsewhere classified	0.000	0.524	0.476
E25 Adrenogenital disorders	0.000	0.524	0.476
E04.9 Non-toxic goitre, unspecified	0.000	0.525	0.475
E50.9 Vitamin A deficiency, unspecified	0.000	0.527	0.473
E50.8 Other manifestations of vitamin A deficiency	0.000	0.527	0.473
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.527	0.473
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.527	0.473
E50.5 Vitamin A deficiency with night blindness	0.000	0.527	0.473
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.527	0.473
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.527	0.473
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.527	0.473
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.527	0.473
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.527	0.473
E56.9 Vitamin deficiency, unspecified	0.000	0.527	0.473
E56.8 Deficiency of other vitamins	0.000	0.527	0.473
E56.1 Deficiency of vitamin K	0.000	0.527	0.473
E56.0 Deficiency of vitamin E	0.000	0.527	0.473
E63.9 Nutritional deficiency, unspecified	0.000	0.527	0.473
E63.8 Other specified nutritional deficiencies	0.000	0.527	0.473
E63.1 Imbalance of constituents of food intake	0.000	0.527	0.473
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.527	0.473
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.527	0.473
E64.8 Sequelae of other nutritional deficiencies	0.000	0.527	0.473
E64.3 Sequelae of rickets	0.000	0.527	0.473
E64.2 Sequelae of vitamin C deficiency	0.000	0.527	0.473
E64.1 Sequelae of vitamin A deficiency	0.000	0.527	0.473
E64.0 Sequelae of protein-energy malnutrition	0.000	0.527	0.473
E34 Other endocrine disorders	0.000	0.529	0.471
E07 Other disorders of thyroid	0.000	0.530	0.470
E26 Hyperaldosteronism	0.000	0.542	0.458
E03.8 Other specified hypothyroidism	0.000	0.545	0.455
E51.9 Thiamine deficiency, unspecified	0.000	0.550	0.450
E51.8 Other manifestations of thiamine deficiency	0.000	0.550	0.450
E51.1 Beriberi	0.000	0.550	0.450
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.558	0.442
E20.8 Other hypoparathyroidism	0.000	0.564	0.436
E20.1 Pseudohypoparathyroidism	0.000	0.564	0.436
E20.0 Idiopathic hypoparathyroidism	0.000	0.564	0.436
E29 Testicular dysfunction	0.000	0.573	0.427
E22 Hyperfunction of pituitary gland	0.000	0.574	0.426
E28 Ovarian dysfunction	0.000	0.575	0.425
E51.2 Wernicke's encephalopathy	0.000	0.582	0.417
E14.9 Without complications	0.000	0.587	0.413
E27.2 Addisonian crisis	0.000	0.591	0.408
E27.5 Adrenomedullary hyperfunction	0.000	0.593	0.407
E27.0 Other adrenocortical overactivity	0.000	0.593	0.407
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.610	0.390
E27.9 Disorder of adrenal gland, unspecified	0.000	0.614	0.386
E65 Localised adiposity	0.000	0.618	0.381
E21.0 Primary hyperparathyroidism	0.000	0.625	0.375
E13.8 With unspecified complications	0.001	0.626	0.373
E13.7 With multiple complications	0.001	0.626	0.373
E13.6 With other specified complications	0.001	0.626	0.373
E13.5 With peripheral circulatory complications	0.001	0.626	0.373
E13.4 With neurological complications	0.001	0.626	0.373
E13.3 With ophthalmic complications	0.001	0.626	0.373
E13.2 With renal complications	0.001	0.626	0.373
E13.1 With ketoacidosis	0.001	0.626	0.373
E13.0 With coma	0.001	0.626	0.373
E34.0 Carcinoid syndrome	0.000	0.630	0.370
E67 Other hyperalimentation	0.000	0.631	0.369
E68 Sequelae of hyperalimentation	0.000	0.631	0.369
E44 Protein-energy malnutrition of moderate and mild degree	0.001	0.640	0.360
E45 Retarded development following protein-energy malnutrition	0.001	0.640	0.360
E43 Unspecified severe protein-energy malnutrition	0.001	0.640	0.360
E42 Marasmic kwashiorkor	0.001	0.640	0.360
E41 Nutritional marasmus	0.001	0.640	0.360
E40 Kwashiorkor	0.001	0.640	0.360
E61.9 Deficiency of nutrient element, unspecified	0.000	0.650	0.350
E61.8 Deficiency of other specified nutrient elements	0.000	0.650	0.350
E61.7 Deficiency of multiple nutrient elements	0.000	0.650	0.350
E61.6 Vanadium deficiency	0.000	0.650	0.350
E61.5 Molybdenum deficiency	0.000	0.650	0.350
E61.4 Chromium deficiency	0.000	0.650	0.350
E61.3 Manganese deficiency	0.000	0.650	0.350
E61.0 Copper deficiency	0.000	0.650	0.350
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.658	0.342
E25.9 Adrenogenital disorder, unspecified	0.000	0.659	0.341
E25.8 Other adrenogenital disorders	0.000	0.659	0.341
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.659	0.341
E30.9 Disorder of puberty, unspecified	0.000	0.659	0.341
E30.8 Other disorders of puberty	0.000	0.659	0.341
E30.1 Precocious puberty	0.000	0.659	0.341
E30.0 Delayed puberty	0.000	0.659	0.341
E31.9 Polyglandular dysfunction, unspecified	0.000	0.659	0.341
E31.8 Other polyglandular dysfunction	0.000	0.659	0.341
E31.1 Polyglandular hyperfunction	0.000	0.659	0.341
E31.0 Autoimmune polyglandular failure	0.000	0.659	0.341
E32.9 Disease of thymus, unspecified	0.000	0.659	0.341
E32.8 Other diseases of thymus	0.000	0.659	0.341
E32.1 Abscess of thymus	0.000	0.659	0.341
E32.0 Persistent hyperplasia of thymus	0.000	0.659	0.341
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.659	0.341
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.659	0.341
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.659	0.341
E24 Cushing's syndrome	0.000	0.661	0.339
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.661	0.339
E34.5 Androgen resistance syndrome	0.000	0.662	0.338
E34.4 Constitutional tall stature	0.000	0.662	0.338
E34.3 Short stature, not elsewhere classified	0.000	0.662	0.338
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.662	0.338
E34.1 Other hypersecretion of intestinal hormones	0.000	0.662	0.338
E07.1 Dyshormogenetic goitre	0.000	0.663	0.337
E07.0 Hypersecretion of calcitonin	0.000	0.663	0.337
E26.0 Primary hyperaldosteronism	0.000	0.663	0.337
E23 Hypofunction and other disorders of pituitary gland	0.000	0.671	0.328
E26.8 Other hyperaldosteronism	0.000	0.672	0.328
E26.1 Secondary hyperaldosteronism	0.000	0.672	0.328
E28.3 Primary ovarian failure	0.000	0.676	0.324
E11.5 With peripheral circulatory complications	0.000	0.677	0.322
E34.9 Endocrine disorder, unspecified	0.000	0.680	0.320
E07.8 Other specified disorders of thyroid	0.000	0.681	0.319
E21.4 Other specified disorders of parathyroid gland	0.000	0.683	0.317
E21.2 Other hyperparathyroidism	0.000	0.683	0.317
E34.8 Other specified endocrine disorders	0.000	0.688	0.312
E29.9 Testicular dysfunction, unspecified	0.000	0.693	0.306
E29.8 Other testicular dysfunction	0.000	0.693	0.306
E29.0 Testicular hyperfunction	0.000	0.693	0.306
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.694	0.306
E22.8 Other hyperfunction of pituitary gland	0.000	0.694	0.306
E61.2 Magnesium deficiency	0.000	0.695	0.304
E28.9 Ovarian dysfunction, unspecified	0.000	0.695	0.304
E28.8 Other ovarian dysfunction	0.000	0.695	0.304
E28.1 Androgen excess	0.000	0.695	0.304
E28.0 Oestrogen excess	0.000	0.695	0.304
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.698	0.302
E26.9 Hyperaldosteronism, unspecified	0.000	0.700	0.300
E27.8 Other specified disorders of adrenal gland	0.000	0.705	0.295
E21.3 Hyperparathyroidism, unspecified	0.000	0.706	0.294
E67.8 Other specified hyperalimentation	0.000	0.735	0.265
E67.3 Hypervitaminosis D	0.000	0.735	0.265
E67.2 Megavitamin-B6 syndrome	0.000	0.735	0.265
E67.1 Hypercarotenaemia	0.000	0.735	0.265
E67.0 Hypervitaminosis A	0.000	0.735	0.265
E22.0 Acromegaly and pituitary gigantism	0.000	0.736	0.264
E23.6 Other disorders of pituitary gland	0.000	0.737	0.263
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.737	0.263
E44.1 Mild protein-energy malnutrition	0.001	0.741	0.258
E44.0 Moderate protein-energy malnutrition	0.001	0.741	0.258
E29.1 Testicular hypofunction	0.000	0.742	0.258
E61.1 Iron deficiency	0.000	0.745	0.255
E22.1 Hyperprolactinaemia	0.000	0.749	0.251
E24.8 Other Cushing's syndrome	0.000	0.756	0.243
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.756	0.243
E24.3 Ectopic ACTH syndrome	0.000	0.756	0.243
E24.1 Nelson's syndrome	0.000	0.756	0.243
E23.7 Disorder of pituitary gland, unspecified	0.000	0.757	0.243
E24.2 Drug-induced Cushing's syndrome	0.000	0.761	0.238
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.764	0.235
E23.1 Drug-induced hypopituitarism	0.000	0.764	0.235
E28.2 Polycystic ovarian syndrome	0.000	0.779	0.221
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.783	0.217
E24.9 Cushing's syndrome, unspecified	0.000	0.794	0.206
E05.5 Thyroid crisis or storm	0.000	0.812	0.188
E05.4 Thyrotoxicosis factitia	0.000	0.812	0.188
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.812	0.188
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.812	0.188
E24.0 Pituitary-dependent Cushing's disease	0.001	0.820	0.180
E13.9 Without complications	0.001	0.820	0.179
E05.8 Other thyrotoxicosis	0.000	0.831	0.169
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.838	0.162
E46 Unspecified protein-energy malnutrition	0.002	0.848	0.150
E07.9 Disorder of thyroid, unspecified	0.000	0.855	0.144
E23.0 Hypopituitarism	0.000	0.856	0.144
E23.2 Diabetes insipidus	0.001	0.858	0.142
E66 Obesity	0.000	0.858	0.142
E05.9 Thyrotoxicosis, unspecified	0.000	0.875	0.125
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.892	0.107
E66.1 Drug-induced obesity	0.000	0.898	0.102
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.902	0.098
E66.0 Obesity due to excess calories	0.000	0.909	0.091
E66.8 Other obesity	0.000	0.929	0.071
R20.2 Paraesthesia of skin	0.036	0.964	0.000
E11.9 Without complications	0.000	0.968	0.032
E70-E90 Metabolic disorders	0.000	0.969	0.031
N81.2 Incomplete uterovaginal prolapse	0.029	0.971	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.977	0.023
E77 Disorders of glycoprotein metabolism	0.000	0.977	0.022
E76 Disorders of glycosaminoglycan metabolism	0.000	0.977	0.022
E72 Other disorders of amino-acid metabolism	0.000	0.977	0.022
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.977	0.022
E70 Disorders of aromatic amino-acid metabolism	0.000	0.977	0.022
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.977	0.022
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.978	0.022
E83 Disorders of mineral metabolism	0.000	0.978	0.022
E79 Disorders of purine and pyrimidine metabolism	0.000	0.978	0.022
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.978	0.022
E84 Cystic fibrosis	0.000	0.979	0.021
E74 Other disorders of carbohydrate metabolism	0.000	0.979	0.021
E83.4 Disorders of magnesium metabolism	0.000	0.980	0.020
E89.2 Postprocedural hypoparathyroidism	0.000	0.981	0.019
E88 Other metabolic disorders	0.000	0.981	0.019
E73 Lactose intolerance	0.000	0.981	0.019
E89.3 Postprocedural hypopituitarism	0.000	0.982	0.018
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.983	0.017
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.983	0.017
E89.5 Postprocedural testicular hypofunction	0.000	0.983	0.017
E89.1 Postprocedural hypoinsulinaemia	0.000	0.983	0.017
E80.6 Other disorders of bilirubin metabolism	0.000	0.983	0.017
E83.1 Disorders of iron metabolism	0.000	0.983	0.017
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.984	0.016
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.984	0.016
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.984	0.016
E70.3 Albinism	0.000	0.984	0.016
E70.2 Disorders of tyrosine metabolism	0.000	0.984	0.016
E70.1 Other hyperphenylalaninaemias	0.000	0.984	0.016
E70.0 Classical phenylketonuria	0.000	0.984	0.016
E71.3 Disorders of fatty-acid metabolism	0.000	0.984	0.016
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.984	0.016
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.984	0.016
E71.0 Maple-syrup-urine disease	0.000	0.984	0.016
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.984	0.016
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.984	0.016
E72.5 Disorders of glycine metabolism	0.000	0.984	0.016
E72.4 Disorders of ornithine metabolism	0.000	0.984	0.016
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.984	0.016
E72.2 Disorders of urea cycle metabolism	0.000	0.984	0.016
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.984	0.016
E72.0 Disorders of amino-acid transport	0.000	0.984	0.016
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.984	0.016
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.984	0.016
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.984	0.016
E76.2 Other mucopolysaccharidoses	0.000	0.984	0.016
E76.1 Mucopolysaccharidosis, type II	0.000	0.984	0.016
E76.0 Mucopolysaccharidosis, type I	0.000	0.984	0.016
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.984	0.016
E77.8 Other disorders of glycoprotein metabolism	0.000	0.984	0.016
E77.1 Defects in glycoprotein degradation	0.000	0.984	0.016
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.984	0.016
E89.4 Postprocedural ovarian failure	0.000	0.984	0.016
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.984	0.016
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.984	0.016
E80.5 Crigler-Najjar syndrome	0.000	0.984	0.016
E80.3 Defects of catalase and peroxydase	0.000	0.984	0.016
E80.2 Other porphyria	0.000	0.984	0.016
E80.1 Porphyria cutanea tarda	0.000	0.984	0.016
E80.0 Hereditary erythropoietic porphyria	0.000	0.984	0.016
E89.0 Postprocedural hypothyroidism	0.000	0.984	0.016
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.984	0.016
E83.8 Other disorders of mineral metabolism	0.000	0.984	0.016
E83.2 Disorders of zinc metabolism	0.000	0.984	0.016
E83.0 Disorders of copper metabolism	0.000	0.984	0.016
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.984	0.016
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.984	0.016
E79.1 Lesch-Nyhan syndrome	0.000	0.984	0.016
E75.6 Lipid storage disorder, unspecified	0.000	0.984	0.016
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.984	0.016
E75.3 Sphingolipidosis, unspecified	0.000	0.984	0.016
E75.2 Other sphingolipidosis	0.000	0.984	0.016
E75.1 Other gangliosidosis	0.000	0.984	0.016
E75.0 GM2 gangliosidosis	0.000	0.984	0.016
E84.8 Cystic fibrosis with other manifestations	0.000	0.984	0.015
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.984	0.015
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.984	0.015
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.984	0.015
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.984	0.015
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.984	0.015
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.984	0.015
E74.2 Disorders of galactose metabolism	0.000	0.984	0.015
E74.1 Disorders of fructose metabolism	0.000	0.984	0.015
E74.0 Glycogen storage disease	0.000	0.984	0.015
E75.5 Other lipid storage disorders	0.000	0.985	0.015
E80.4 Gilbert's syndrome	0.000	0.985	0.015
E85 Amyloidosis	0.000	0.985	0.015
E84.9 Cystic fibrosis, unspecified	0.000	0.985	0.014
R20 Disturbances of skin sensation	0.014	0.986	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.986	0.014
Y85.0 Sequelae of motor-vehicle accident	0.000	0.986	0.014
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.986	0.014
E73.8 Other lactose intolerance	0.000	0.986	0.013
E73.1 Secondary lactase deficiency	0.000	0.986	0.013
E73.0 Congenital lactase deficiency	0.000	0.986	0.013
E86 Volume depletion	0.000	0.986	0.014
E88.2 Lipomatosis, not elsewhere classified	0.000	0.987	0.013
E83.3 Disorders of phosphorus metabolism	0.000	0.987	0.013
E88.8 Other specified metabolic disorders	0.000	0.988	0.012
R20.3 Hyperaesthesia	0.012	0.988	0.000
E88.9 Metabolic disorder, unspecified	0.000	0.988	0.012
E88.3 Tumour lysis syndrome	0.000	0.989	0.011
H36.0 Diabetic retinopathy	0.000	0.989	0.011
E85.8 Other amyloidosis	0.000	0.989	0.011
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.989	0.011
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.989	0.011
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.989	0.011
E85.3 Secondary systemic amyloidosis	0.000	0.989	0.010
E83.5 Disorders of calcium metabolism	0.000	0.989	0.011
M19.97 Arthrosis, unspecified (Ankle and foot)	0.011	0.989	0.000
R20.1 Hypoaesthesia of skin	0.010	0.990	0.000
R20.0 Anaesthesia of skin	0.010	0.990	0.000
E73.9 Lactose intolerance, unspecified	0.000	0.990	0.010
E85.4 Organ-limited amyloidosis	0.000	0.991	0.009
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.991	0.009
R20.8 Other and unspecified disturbances of skin sensation	0.008	0.992	0.000
E78.2 Mixed hyperlipidaemia	0.000	0.992	0.008
E85.9 Amyloidosis, unspecified	0.001	0.993	0.007
Z87.8 Personal history of other specified conditions	0.000	0.993	0.007
E78.1 Pure hyperglyceridaemia	0.000	0.993	0.007
E78.4 Other hyperlipidaemia	0.000	0.993	0.007
I35.0 Aortic (valve) stenosis	0.007	0.993	0.000
E78.6 Lipoprotein deficiency	0.000	0.993	0.007
Y85 Sequelae of transport accidents	0.000	0.993	0.007
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.993	0.007
E78.3 Hyperchylomicronaemia	0.000	0.993	0.006
L40.9 Psoriasis, unspecified	0.000	0.994	0.006
S70.9 Superficial injury of hip and thigh, unspecified	0.005	0.995	0.000
K91.4 Colostomy and enterostomy malfunction	0.000	0.995	0.005
K90.0 Coeliac disease	0.000	0.995	0.005
Y85.9 Sequelae of other and unspecified transport accidents	0.000	0.995	0.005
L40 Psoriasis	0.000	0.995	0.005
H36 Retinal disorders in diseases classified elsewhere	0.000	0.995	0.005
E78.8 Other disorders of lipoprotein metabolism	0.000	0.995	0.005
L40.0 Psoriasis vulgaris	0.000	0.995	0.005
S52.60 Fracture of lower end of both ulna and radius (closed)	0.000	0.995	0.005
L40.8 Other psoriasis	0.000	0.995	0.004
L40.5 Arthropathic psoriasis	0.000	0.995	0.005
E66.9 Obesity, unspecified	0.000	0.996	0.004
L40.4 Guttate psoriasis	0.000	0.996	0.004
L40.2 Acrodermatitis continua	0.000	0.996	0.004
H36.8 Other retinal disorders in diseases classified elsewhere	0.000	0.996	0.004
M35.0 Sicca syndrome [Sjogren]	0.000	0.996	0.004
L40.1 Generalised pustular psoriasis	0.000	0.996	0.003
L40.3 Pustulosis palmaris et plantaris	0.000	0.997	0.003
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.997	0.003
S60.9 Superficial injury of wrist and hand, unspecified	0.000	0.997	0.003
Q66 Congenital deformities of feet	0.003	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.997	0.003
Q66.9 Congenital deformity of feet, unspecified	0.003	0.997	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.000	0.997	0.003
D06.9 Cervix, unspecified	0.000	0.997	0.003
Q65 Congenital deformities of hip	0.003	0.997	0.000
K14.8 Other diseases of tongue	0.000	0.997	0.003
Q44.6 Cystic disease of liver	0.003	0.997	0.000
Q65.8 Other congenital deformities of hip	0.003	0.997	0.000
Q76.0 Spina bifida occulta	0.003	0.997	0.000
M31.3 Wegener's granulomatosis	0.003	0.997	0.000
M35.1 Other overlap syndromes	0.000	0.997	0.003
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
M35 Other systemic involvement of connective tissue	0.000	0.997	0.003
M31.6 Other giant cell arteritis	0.003	0.997	0.000
M35.7 Hypermobility syndrome	0.000	0.997	0.003
Q66.2 Metatarsus varus	0.003	0.997	0.000
Q66.0 Talipes equinovarus	0.003	0.997	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.003	0.997	0.000
L29.9 Pruritus, unspecified	0.000	0.997	0.003
Q66.3 Other congenital varus deformities of feet	0.003	0.997	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.997	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.003	0.997	0.000
E87.4 Mixed disorder of acid-base balance	0.000	0.997	0.003
Q66.6 Other congenital valgus deformities of feet	0.003	0.997	0.000
Q66.5 Congenital pes planus	0.003	0.997	0.000
Q66.4 Talipes calcaneovalgus	0.003	0.997	0.000
Q66.1 Talipes calcaneovarus	0.003	0.997	0.000
I34.0 Mitral (valve) insufficiency	0.000	0.997	0.003
Q76.9 Congenital malformation of bony thorax, unspecified	0.002	0.997	0.000
Q76.8 Other congenital malformations of bony thorax	0.002	0.997	0.000
Q76.7 Congenital malformation of sternum	0.002	0.997	0.000
Q76.6 Other congenital malformations of ribs	0.002	0.997	0.000
Q76.5 Cervical rib	0.002	0.997	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.002	0.997	0.000
Q76.2 Congenital spondylolisthesis	0.002	0.997	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.997	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q75 Other congenital malformations of skull and face bones	0.003	0.997	0.000
Q73 Reduction defects of unspecified limb	0.003	0.997	0.000
Q72 Reduction defects of lower limb	0.003	0.997	0.000
Q71 Reduction defects of upper limb	0.003	0.997	0.000
Q70 Syndactyly	0.003	0.997	0.000
Q69 Polydactyly	0.003	0.997	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
Q51.2 Other doubling of uterus	0.003	0.997	0.000
Q66.7 Pes cavus	0.002	0.997	0.000
Q44.5 Other congenital malformations of bile ducts	0.002	0.997	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.003	0.997	0.000
E87.3 Alkalosis	0.000	0.997	0.003
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.997	0.000
Q43 Other congenital malformations of intestine	0.002	0.997	0.000
M34.9 Systemic sclerosis, unspecified	0.000	0.997	0.003
Q43.9 Congenital malformation of intestine, unspecified	0.002	0.997	0.000
Q65.9 Congenital deformity of hip, unspecified	0.002	0.997	0.000
Q65.6 Unstable hip	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations