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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9380351
log Bayes Factor = 9.11795
Chromosome 6   position 33,129,746  (GRCh37) Explore rs9380351 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.005 0.995
E10.1 With ketoacidosis
0.000 0.018 0.982
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.020 0.980
E00-E07 Disorders of thyroid gland
0.000 0.035 0.965
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.035 0.965
E16 Other disorders of pancreatic internal secretion
0.000 0.045 0.955
E16.2 Hypoglycaemia, unspecified
0.000 0.053 0.947
E10.5 With peripheral circulatory complications
0.000 0.053 0.947
E11 Non-insulin-dependent diabetes mellitus
0.000 0.063 0.937
E06 Thyroiditis
0.000 0.066 0.934
E04 Other non-toxic goitre
0.000 0.081 0.919
E06.3 Autoimmune thyroiditis
0.000 0.094 0.906
E11.4 With neurological complications
0.000 0.095 0.905
E10.2 With renal complications
0.000 0.097 0.903
E50-E64 Other nutritional deficiencies
0.000 0.107 0.893
E03 Other hypothyroidism
0.000 0.149 0.851
E04.2 Non-toxic multinodular goitre
0.000 0.152 0.848
E11.1 With ketoacidosis
0.000 0.154 0.846
E04.1 Non-toxic single thyroid nodule
0.000 0.157 0.843
E10.6 With other specified complications
0.000 0.157 0.843
E10.4 With neurological complications
0.000 0.166 0.834
E14 Unspecified diabetes mellitus
0.000 0.193 0.807
E53 Deficiency of other B group vitamins
0.000 0.194 0.806
E55 Vitamin D deficiency
0.000 0.203 0.797
E03.9 Hypothyroidism, unspecified
0.000 0.212 0.788
E11.3 With ophthalmic complications
0.000 0.214 0.786
E53.8 Deficiency of other specified B group vitamins
0.000 0.242 0.758
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.249 0.751
E10.0 With coma
0.000 0.257 0.743
E14.3 With ophthalmic complications
0.000 0.263 0.737
E55.9 Vitamin D deficiency, unspecified
0.000 0.272 0.728
E06.9 Thyroiditis, unspecified
0.000 0.272 0.728
E11.2 With renal complications
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
E11.6 With other specified complications
0.000 0.283 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.286 0.713
E04.0 Non-toxic diffuse goitre
0.000 0.291 0.709
E10.8 With unspecified complications
0.000 0.296 0.704
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.308 0.692
E00 Congenital iodine-deficiency syndrome
0.000 0.308 0.692
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.308 0.692
E15 Nondiabetic hypoglycaemic coma
0.000 0.308 0.692
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.315 0.685
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.315 0.685
E16.4 Abnormal secretion of gastrin
0.000 0.315 0.685
E16.3 Increased secretion of glucagon
0.000 0.315 0.685
E11.8 With unspecified complications
0.000 0.328 0.672
E11.7 With multiple complications
0.000 0.328 0.672
E06.5 Other chronic thyroiditis
0.000 0.330 0.670
E06.4 Drug-induced thyroiditis
0.000 0.330 0.670
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.330 0.670
E06.1 Subacute thyroiditis
0.000 0.330 0.670
E06.0 Acute thyroiditis
0.000 0.330 0.670
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.330 0.670
E04.8 Other specified non-toxic goitre
0.000 0.341 0.659
E20-E35 Disorders of other endocrine glands
0.000 0.351 0.649
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.359 0.640
E63 Other nutritional deficiencies
0.000 0.359 0.640
E56 Other vitamin deficiencies
0.000 0.359 0.640
E50 Vitamin A deficiency
0.000 0.359 0.640
E60 Dietary zinc deficiency
0.000 0.359 0.640
E59 Dietary selenium deficiency
0.000 0.359 0.640
E58 Dietary calcium deficiency
0.000 0.359 0.640
E54 Ascorbic acid deficiency
0.000 0.359 0.640
E52 Niacin deficiency [pellagra]
0.000 0.359 0.640
E16.1 Other hypoglycaemia
0.000 0.373 0.627
E11.0 With coma
0.000 0.387 0.613
E03.5 Myxoedema coma
0.000 0.390 0.610
E03.4 Atrophy of thyroid (acquired)
0.000 0.390 0.610
E03.3 Postinfectious hypothyroidism
0.000 0.390 0.610
E03.1 Congenital hypothyroidism without goitre
0.000 0.390 0.610
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.390 0.610
E51 Thiamine deficiency
0.000 0.393 0.607
E20 Hypoparathyroidism
0.000 0.407 0.593
E14.8 With unspecified complications
0.000 0.421 0.579
E14.7 With multiple complications
0.000 0.422 0.578
E14.6 With other specified complications
0.000 0.422 0.578
E14.5 With peripheral circulatory complications
0.000 0.422 0.578
E14.2 Withrenal complications
0.000 0.422 0.578
E14.0 With coma
0.000 0.422 0.578
E53.1 Pyridoxine deficiency
0.000 0.422 0.578
E53.0 Riboflavin deficiency
0.000 0.422 0.578
E14.1 With ketoacidosis
0.000 0.427 0.573
E55.0 Rickets, active
0.000 0.429 0.571
E14.4 With neurological complications
0.000 0.429 0.571
E20.9 Hypoparathyroidism, unspecified
0.000 0.448 0.552
E27 Other disorders of adrenal gland
0.000 0.450 0.550
E13 Other specified diabetes mellitus
0.000 0.471 0.528
E27.1 Primary adrenocortical insufficiency
0.000 0.477 0.523
E12.9 Without complications
0.000 0.488 0.512
E12.8 With unspecified complications
0.000 0.488 0.512
E12.7 With multiple complications
0.000 0.488 0.512
E12.6 With other specified complications
0.000 0.488 0.512
E12.5 With peripheral circulatory complications
0.000 0.488 0.512
E12.4 With neurological complications
0.000 0.488 0.512
E12.3 With ophthalmic complications
0.000 0.488 0.512
E12.2 With renal complications
0.000 0.488 0.512
E12.1 With ketoacidosis
0.000 0.488 0.512
E12.0 With coma
0.000 0.488 0.512
E53.9 Vitamin B deficiency, unspecified
0.000 0.495 0.505
E40-E46 Malnutrition
0.001 0.503 0.496
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.503 0.496
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.503 0.496
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.503 0.496
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.503 0.496
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.503 0.496
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.503 0.496
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.503 0.496
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.503 0.496
E34 Other endocrine disorders
0.000 0.510 0.490
E65-E68 Obesity and other hyperalimentation
0.000 0.511 0.489
E61 Deficiency of other nutrient elements
0.000 0.523 0.477
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.534 0.466
E32 Diseases of thymus
0.000 0.534 0.466
E31 Polyglandular dysfunction
0.000 0.534 0.466
E30 Disorders of puberty, not elsewhere classified
0.000 0.534 0.466
E25 Adrenogenital disorders
0.000 0.534 0.466
E22 Hyperfunction of pituitary gland
0.000 0.539 0.461
E50.9 Vitamin A deficiency, unspecified
0.000 0.541 0.459
E50.8 Other manifestations of vitamin A deficiency
0.000 0.541 0.459
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.541 0.459
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.541 0.459
E50.5 Vitamin A deficiency with night blindness
0.000 0.541 0.459
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.541 0.459
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.541 0.459
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.541 0.459
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.541 0.459
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.541 0.459
E56.9 Vitamin deficiency, unspecified
0.000 0.541 0.459
E56.8 Deficiency of other vitamins
0.000 0.541 0.459
E56.1 Deficiency of vitamin K
0.000 0.541 0.459
E56.0 Deficiency of vitamin E
0.000 0.541 0.459
E63.9 Nutritional deficiency, unspecified
0.000 0.541 0.459
E63.8 Other specified nutritional deficiencies
0.000 0.541 0.459
E63.1 Imbalance of constituents of food intake
0.000 0.541 0.459
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.541 0.459
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.541 0.459
E64.8 Sequelae of other nutritional deficiencies
0.000 0.541 0.459
E64.3 Sequelae of rickets
0.000 0.541 0.459
E64.2 Sequelae of vitamin C deficiency
0.000 0.541 0.459
E64.1 Sequelae of vitamin A deficiency
0.000 0.541 0.459
E64.0 Sequelae of protein-energy malnutrition
0.000 0.541 0.459
E07 Other disorders of thyroid
0.000 0.541 0.459
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.562 0.438
E51.9 Thiamine deficiency, unspecified
0.000 0.564 0.435
E51.8 Other manifestations of thiamine deficiency
0.000 0.564 0.435
E51.1 Beriberi
0.000 0.564 0.435
E03.8 Other specified hypothyroidism
0.000 0.572 0.428
E26 Hyperaldosteronism
0.000 0.573 0.426
E20.8 Other hypoparathyroidism
0.000 0.575 0.425
E20.1 Pseudohypoparathyroidism
0.000 0.575 0.425
E20.0 Idiopathic hypoparathyroidism
0.000 0.575 0.425
E28 Ovarian dysfunction
0.000 0.593 0.407
E51.2 Wernicke's encephalopathy
0.000 0.598 0.402
E04.9 Non-toxic goitre, unspecified
0.000 0.599 0.401
E34.0 Carcinoid syndrome
0.000 0.603 0.397
E27.5 Adrenomedullary hyperfunction
0.000 0.606 0.394
E27.0 Other adrenocortical overactivity
0.000 0.606 0.394
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.608 0.392
E27.2 Addisonian crisis
0.000 0.609 0.391
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.610 0.390
E29 Testicular dysfunction
0.000 0.613 0.387
E14.9 Without complications
0.000 0.616 0.384
E13.8 With unspecified complications
0.000 0.621 0.379
E13.7 With multiple complications
0.000 0.621 0.379
E13.6 With other specified complications
0.000 0.621 0.379
E13.5 With peripheral circulatory complications
0.000 0.621 0.379
E13.4 With neurological complications
0.000 0.621 0.379
E13.3 With ophthalmic complications
0.000 0.621 0.379
E13.2 With renal complications
0.000 0.621 0.379
E13.1 With ketoacidosis
0.000 0.621 0.379
E13.0 With coma
0.000 0.621 0.379
E21.0 Primary hyperparathyroidism
0.000 0.625 0.375
E27.9 Disorder of adrenal gland, unspecified
0.000 0.633 0.367
E44 Protein-energy malnutrition of moderate and mild degree
0.001 0.644 0.356
E45 Retarded development following protein-energy malnutrition
0.001 0.644 0.356
E43 Unspecified severe protein-energy malnutrition
0.001 0.644 0.356
E42 Marasmic kwashiorkor
0.001 0.644 0.356
E41 Nutritional marasmus
0.001 0.644 0.356
E40 Kwashiorkor
0.001 0.644 0.356
E65 Localised adiposity
0.000 0.645 0.355
E34.5 Androgen resistance syndrome
0.000 0.648 0.351
E34.4 Constitutional tall stature
0.000 0.648 0.351
E34.3 Short stature, not elsewhere classified
0.000 0.648 0.351
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.648 0.351
E34.1 Other hypersecretion of intestinal hormones
0.000 0.648 0.351
E67 Other hyperalimentation
0.000 0.649 0.350
E68 Sequelae of hyperalimentation
0.000 0.649 0.350
E34.9 Endocrine disorder, unspecified
0.000 0.650 0.350
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.654 0.346
E11.5 With peripheral circulatory complications
0.000 0.656 0.344
E61.9 Deficiency of nutrient element, unspecified
0.000 0.658 0.342
E61.8 Deficiency of other specified nutrient elements
0.000 0.658 0.342
E61.7 Deficiency of multiple nutrient elements
0.000 0.658 0.342
E61.6 Vanadium deficiency
0.000 0.658 0.342
E61.5 Molybdenum deficiency
0.000 0.658 0.342
E61.4 Chromium deficiency
0.000 0.658 0.342
E61.3 Manganese deficiency
0.000 0.658 0.342
E61.0 Copper deficiency
0.000 0.658 0.342
E25.9 Adrenogenital disorder, unspecified
0.000 0.666 0.334
E25.8 Other adrenogenital disorders
0.000 0.666 0.334
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.666 0.334
E30.9 Disorder of puberty, unspecified
0.000 0.666 0.334
E30.8 Other disorders of puberty
0.000 0.666 0.334
E30.1 Precocious puberty
0.000 0.666 0.334
E30.0 Delayed puberty
0.000 0.666 0.334
E31.9 Polyglandular dysfunction, unspecified
0.000 0.666 0.334
E31.8 Other polyglandular dysfunction
0.000 0.666 0.334
E31.1 Polyglandular hyperfunction
0.000 0.666 0.334
E31.0 Autoimmune polyglandular failure
0.000 0.666 0.334
E32.9 Disease of thymus, unspecified
0.000 0.666 0.334
E32.8 Other diseases of thymus
0.000 0.666 0.334
E32.1 Abscess of thymus
0.000 0.666 0.334
E32.0 Persistent hyperplasia of thymus
0.000 0.666 0.334
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.666 0.334
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.666 0.334
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.666 0.334
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.669 0.330
E22.8 Other hyperfunction of pituitary gland
0.000 0.669 0.330
E07.1 Dyshormogenetic goitre
0.000 0.671 0.329
E07.0 Hypersecretion of calcitonin
0.000 0.671 0.329
E24 Cushing's syndrome
0.000 0.678 0.322
E34.8 Other specified endocrine disorders
0.000 0.679 0.321
E21.4 Other specified disorders of parathyroid gland
0.000 0.686 0.314
E21.2 Other hyperparathyroidism
0.000 0.686 0.314
E23 Hypofunction and other disorders of pituitary gland
0.000 0.686 0.313
E61.2 Magnesium deficiency
0.000 0.690 0.310
E28.3 Primary ovarian failure
0.000 0.693 0.307
E07.8 Other specified disorders of thyroid
0.000 0.693 0.307
E26.8 Other hyperaldosteronism
0.000 0.694 0.306
E26.1 Secondary hyperaldosteronism
0.000 0.694 0.306
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.702 0.298
E26.0 Primary hyperaldosteronism
0.000 0.704 0.296
E22.0 Acromegaly and pituitary gigantism
0.000 0.705 0.295
E27.8 Other specified disorders of adrenal gland
0.000 0.706 0.293
E21.3 Hyperparathyroidism, unspecified
0.000 0.707 0.293
E28.9 Ovarian dysfunction, unspecified
0.000 0.708 0.292
E28.8 Other ovarian dysfunction
0.000 0.708 0.292
E28.1 Androgen excess
0.000 0.708 0.292
E28.0 Oestrogen excess
0.000 0.708 0.292
E26.9 Hyperaldosteronism, unspecified
0.000 0.721 0.278
E29.9 Testicular dysfunction, unspecified
0.000 0.722 0.278
E29.8 Other testicular dysfunction
0.000 0.722 0.278
E29.0 Testicular hyperfunction
0.000 0.722 0.278
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.728 0.272
E22.1 Hyperprolactinaemia
0.000 0.734 0.266
E44.1 Mild protein-energy malnutrition
0.001 0.744 0.255
E44.0 Moderate protein-energy malnutrition
0.001 0.744 0.255
E67.8 Other specified hyperalimentation
0.000 0.748 0.251
E67.3 Hypervitaminosis D
0.000 0.748 0.251
E67.2 Megavitamin-B6 syndrome
0.000 0.748 0.251
E67.1 Hypercarotenaemia
0.000 0.748 0.251
E67.0 Hypervitaminosis A
0.000 0.748 0.251
E23.6 Other disorders of pituitary gland
0.000 0.751 0.249
E61.1 Iron deficiency
0.000 0.765 0.235
E24.8 Other Cushing's syndrome
0.000 0.769 0.231
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.769 0.231
E24.3 Ectopic ACTH syndrome
0.000 0.769 0.231
E24.1 Nelson's syndrome
0.000 0.769 0.231
E23.7 Disorder of pituitary gland, unspecified
0.000 0.770 0.230
E24.2 Drug-induced Cushing's syndrome
0.000 0.774 0.225
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.775 0.225
E23.1 Drug-induced hypopituitarism
0.000 0.775 0.225
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.001 0.789 0.211
E28.2 Polycystic ovarian syndrome
0.000 0.794 0.206
E29.1 Testicular hypofunction
0.000 0.801 0.199
E05.5 Thyroid crisis or storm
0.000 0.805 0.195
E05.4 Thyrotoxicosis factitia
0.000 0.805 0.195
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.805 0.195
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.805 0.195
E13.9 Without complications
0.001 0.806 0.193
E24.9 Cushing's syndrome, unspecified
0.000 0.809 0.190
E05.8 Other thyrotoxicosis
0.000 0.826 0.173
E24.0 Pituitary-dependent Cushing's disease
0.001 0.830 0.169
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.836 0.163
E23.2 Diabetes insipidus
0.000 0.843 0.157
E46 Unspecified protein-energy malnutrition
0.001 0.850 0.149
E07.9 Disorder of thyroid, unspecified
0.000 0.852 0.148
E05.9 Thyrotoxicosis, unspecified
0.000 0.853 0.147
E66 Obesity
0.000 0.876 0.124
E23.0 Hypopituitarism
0.000 0.885 0.114
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.897 0.103
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.907 0.093
E66.1 Drug-induced obesity
0.000 0.911 0.089
E66.0 Obesity due to excess calories
0.000 0.922 0.078
R20.2 Paraesthesia of skin
0.070 0.930 0.000
E66.8 Other obesity
0.000 0.942 0.058
E70-E90 Metabolic disorders
0.000 0.946 0.054
E11.9 Without complications
0.000 0.955 0.045
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.958 0.042
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.959 0.041
E77 Disorders of glycoprotein metabolism
0.000 0.961 0.039
E76 Disorders of glycosaminoglycan metabolism
0.000 0.961 0.039
E72 Other disorders of amino-acid metabolism
0.000 0.961 0.039
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.961 0.039
E70 Disorders of aromatic amino-acid metabolism
0.000 0.961 0.039
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.961 0.039
E79 Disorders of purine and pyrimidine metabolism
0.000 0.962 0.038
E83 Disorders of mineral metabolism
0.000 0.962 0.038
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.962 0.038
E84 Cystic fibrosis
0.000 0.963 0.037
E74 Other disorders of carbohydrate metabolism
0.000 0.964 0.036
E89.2 Postprocedural hypoparathyroidism
0.000 0.964 0.035
E83.4 Disorders of magnesium metabolism
0.000 0.966 0.034
E73 Lactose intolerance
0.000 0.966 0.034
E86 Volume depletion
0.000 0.969 0.031
E88 Other metabolic disorders
0.000 0.969 0.031
E80.6 Other disorders of bilirubin metabolism
0.000 0.969 0.030
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.970 0.030
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.970 0.030
E89.5 Postprocedural testicular hypofunction
0.000 0.970 0.030
E89.1 Postprocedural hypoinsulinaemia
0.000 0.970 0.030
E89.4 Postprocedural ovarian failure
0.000 0.970 0.030
E89.3 Postprocedural hypopituitarism
0.000 0.970 0.030
E80.4 Gilbert's syndrome
0.000 0.970 0.030
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.971 0.029
E80.5 Crigler-Najjar syndrome
0.000 0.971 0.029
E80.3 Defects of catalase and peroxydase
0.000 0.971 0.029
E80.2 Other porphyria
0.000 0.971 0.029
E80.1 Porphyria cutanea tarda
0.000 0.971 0.029
E80.0 Hereditary erythropoietic porphyria
0.000 0.971 0.029
E89.0 Postprocedural hypothyroidism
0.000 0.971 0.029
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.971 0.029
E85 Amyloidosis
0.000 0.971 0.028
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.972 0.028
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.972 0.028
E70.3 Albinism
0.000 0.972 0.028
E70.2 Disorders of tyrosine metabolism
0.000 0.972 0.028
E70.1 Other hyperphenylalaninaemias
0.000 0.972 0.028
E70.0 Classical phenylketonuria
0.000 0.972 0.028
E71.3 Disorders of fatty-acid metabolism
0.000 0.972 0.028
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.972 0.028
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.972 0.028
E71.0 Maple-syrup-urine disease
0.000 0.972 0.028
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.972 0.028
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.972 0.028
E72.5 Disorders of glycine metabolism
0.000 0.972 0.028
E72.4 Disorders of ornithine metabolism
0.000 0.972 0.028
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.972 0.028
E72.2 Disorders of urea cycle metabolism
0.000 0.972 0.028
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.972 0.028
E72.0 Disorders of amino-acid transport
0.000 0.972 0.028
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.972 0.028
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.972 0.028
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.972 0.028
E76.2 Other mucopolysaccharidoses
0.000 0.972 0.028
E76.1 Mucopolysaccharidosis, type II
0.000 0.972 0.028
E76.0 Mucopolysaccharidosis, type I
0.000 0.972 0.028
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.972 0.028
E77.8 Other disorders of glycoprotein metabolism
0.000 0.972 0.028
E77.1 Defects in glycoprotein degradation
0.000 0.972 0.028
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.972 0.028
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.972 0.027
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.972 0.027
E79.1 Lesch-Nyhan syndrome
0.000 0.972 0.027
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.973 0.027
E83.8 Other disorders of mineral metabolism
0.000 0.973 0.027
E83.2 Disorders of zinc metabolism
0.000 0.973 0.027
E83.0 Disorders of copper metabolism
0.000 0.973 0.027
E75.6 Lipid storage disorder, unspecified
0.000 0.973 0.027
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.973 0.027
E75.3 Sphingolipidosis, unspecified
0.000 0.973 0.027
E75.2 Other sphingolipidosis
0.000 0.973 0.027
E75.1 Other gangliosidosis
0.000 0.973 0.027
E75.0 GM2 gangliosidosis
0.000 0.973 0.027
E84.8 Cystic fibrosis with other manifestations
0.000 0.973 0.027
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.973 0.027
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.973 0.027
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.973 0.026
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.974 0.026
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.974 0.026
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.974 0.026
E74.2 Disorders of galactose metabolism
0.000 0.974 0.026
E74.1 Disorders of fructose metabolism
0.000 0.974 0.026
E74.0 Glycogen storage disease
0.000 0.974 0.026
E75.5 Other lipid storage disorders
0.000 0.974 0.026
E83.1 Disorders of iron metabolism
0.000 0.974 0.026
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.975 0.025
E73.8 Other lactose intolerance
0.000 0.975 0.025
E73.1 Secondary lactase deficiency
0.000 0.975 0.025
E73.0 Congenital lactase deficiency
0.000 0.975 0.025
E84.9 Cystic fibrosis, unspecified
0.000 0.975 0.024
R20 Disturbances of skin sensation
0.024 0.976 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.977 0.023
E83.3 Disorders of phosphorus metabolism
0.000 0.977 0.023
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.978 0.022
E88.2 Lipomatosis, not elsewhere classified
0.000 0.979 0.021
E85.3 Secondary systemic amyloidosis
0.000 0.979 0.021
E85.8 Other amyloidosis
0.000 0.979 0.020
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.979 0.020
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.979 0.020
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.979 0.020
E73.9 Lactose intolerance, unspecified
0.000 0.980 0.020
R20.3 Hyperaesthesia
0.020 0.980 0.000
E88.8 Other specified metabolic disorders
0.000 0.980 0.019
E88.9 Metabolic disorder, unspecified
0.000 0.981 0.019
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.981 0.019
E83.5 Disorders of calcium metabolism
0.000 0.982 0.018
E88.3 Tumour lysis syndrome
0.000 0.982 0.018
E85.4 Organ-limited amyloidosis
0.000 0.982 0.018
R20.1 Hypoaesthesia of skin
0.018 0.982 0.000
L40.9 Psoriasis, unspecified
0.000 0.983 0.017
R20.0 Anaesthesia of skin
0.016 0.984 0.000
E78.2 Mixed hyperlipidaemia
0.000 0.984 0.016
E78.1 Pure hyperglyceridaemia
0.000 0.984 0.016
M19.97 Arthrosis, unspecified (Ankle and foot)
0.015 0.985 0.000
L40 Psoriasis
0.000 0.985 0.015
E78.4 Other hyperlipidaemia
0.000 0.985 0.015
E85.9 Amyloidosis, unspecified
0.000 0.985 0.014
E78.6 Lipoprotein deficiency
0.000 0.986 0.014
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.986 0.014
L40.5 Arthropathic psoriasis
0.000 0.986 0.014
E78.3 Hyperchylomicronaemia
0.000 0.986 0.014
L40.8 Other psoriasis
0.000 0.987 0.013
R20.8 Other and unspecified disturbances of skin sensation
0.013 0.987 0.000
Y85.0 Sequelae of motor-vehicle accident
0.000 0.987 0.013
L40.0 Psoriasis vulgaris
0.000 0.987 0.013
L40.4 Guttate psoriasis
0.000 0.989 0.011
L40.3 Pustulosis palmaris et plantaris
0.000 0.989 0.011
L40.2 Acrodermatitis continua
0.000 0.989 0.011
E78.8 Other disorders of lipoprotein metabolism
0.000 0.989 0.010
L40.1 Generalised pustular psoriasis
0.000 0.990 0.010
H36.0 Diabetic retinopathy
0.000 0.990 0.010
K91.4 Colostomy and enterostomy malfunction
0.000 0.991 0.009
N81.2 Incomplete uterovaginal prolapse
0.008 0.992 0.000
I35.0 Aortic (valve) stenosis
0.007 0.993 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.007 0.993 0.000
Y85 Sequelae of transport accidents
0.000 0.994 0.006
L40-L45 Papulosquamous disorders
0.000 0.994 0.006
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.995 0.005
C73 Malignant neoplasm of thyroid gland
0.000 0.995 0.005
M35.0 Sicca syndrome [Sjogren]
0.000 0.995 0.005
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.995 0.005
L42 Pityriasis rosea
0.000 0.995 0.005
Y85.9 Sequelae of other and unspecified transport accidents
0.000 0.995 0.005
H36 Retinal disorders in diseases classified elsewhere
0.000 0.995 0.004
L44 Other papulosquamous disorders
0.000 0.996 0.004
L41 Parapsoriasis
0.000 0.996 0.004
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.996 0.004
Z87.8 Personal history of other specified conditions
0.000 0.996 0.004
M35.1 Other overlap syndromes
0.000 0.996 0.004
M35.7 Hypermobility syndrome
0.000 0.996 0.004
M35 Other systemic involvement of connective tissue
0.000 0.996 0.004
E87.4 Mixed disorder of acid-base balance
0.000 0.996 0.004
E87.3 Alkalosis
0.000 0.996 0.004
Q76 Congenital malformations of spine and bony thorax
0.004 0.996 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.004 0.996 0.000
I34.0 Mitral (valve) insufficiency
0.000 0.996 0.004
Q66 Congenital deformities of feet
0.004 0.996 0.000
Q65 Congenital deformities of hip
0.004 0.996 0.000
Q65.8 Other congenital deformities of hip
0.004 0.996 0.000
Q76.0 Spina bifida occulta
0.004 0.996 0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis
0.004 0.996 0.000
Z89.5 Acquired absence of leg at or below knee
0.000 0.996 0.004
K90.0 Coeliac disease
0.000 0.996 0.004
Q66.9 Congenital deformity of feet, unspecified
0.003 0.996 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.996 0.003
L41.9 Parapsoriasis, unspecified
0.000 0.997 0.003
L41.8 Other parapsoriasis
0.000 0.997 0.003
L41.5 Retiform parapsoriasis
0.000 0.997 0.003
L41.4 Large plaque parapsoriasis
0.000 0.997 0.003
L41.3 Small plaque parapsoriasis
0.000 0.997 0.003
L41.2 Lymphomatoid papulosis
0.000 0.997 0.003
L41.1 Pityriasis lichenoides chronica
0.000 0.997 0.003
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.997 0.003
L44.9 Papulosquamous disorder, unspecified
0.000 0.997 0.003
L44.8 Other specified papulosquamous disorders
0.000 0.997 0.003
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.997 0.003
L44.3 Lichen ruber moniliformis
0.000 0.997 0.003
L44.2 Lichen striatus
0.000 0.997 0.003
L44.1 Lichen nitidus
0.000 0.997 0.003
L44.0 Pityriasis rubra pilaris
0.000 0.997 0.003
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.997 0.003
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.997 0.003
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.997 0.003
M35.5 Multifocal fibrosclerosis
0.000 0.997 0.003
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.997 0.003
M35.2 Behcet's disease
0.000 0.997 0.003
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.003 0.997 0.000
Q44.6 Cystic disease of liver
0.003 0.997 0.000
E87.0 Hyperosmolality and hypernatraemia
0.000 0.997 0.003
Q66.2 Metatarsus varus
0.003 0.997 0.000
Q66.0 Talipes equinovarus
0.003 0.997 0.000
Q76.9 Congenital malformation of bony thorax, unspecified
0.003 0.997 0.000
Q76.8 Other congenital malformations of bony thorax
0.003 0.997 0.000
Q76.7 Congenital malformation of sternum
0.003 0.997 0.000
Q76.6 Other congenital malformations of ribs
0.003 0.997 0.000
Q76.5 Cervical rib
0.003 0.997 0.000
Q76.3 Congenital scoliosis due to congenital bony malformation
0.003 0.997 0.000
Q76.2 Congenital spondylolisthesis
0.003 0.997 0.000
Q76.1 Klippel-Feil syndrome
0.003 0.997 0.000
Z89.6 Acquired absence of leg above knee
0.000 0.997 0.003
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.003 0.997 0.000
Q75 Other congenital malformations of skull and face bones
0.003 0.997 0.000
Q73 Reduction defects of unspecified limb
0.003 0.997 0.000
Q72 Reduction defects of lower limb
0.003 0.997 0.000
Q71 Reduction defects of upper limb
0.003 0.997 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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