TreeWAS – Variant ID: rs9400467

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.909	0.091
F31.9 Bipolar affective disorder, unspecified	0.028	0.972	0.000
F31 Bipolar affective disorder	0.025	0.975	0.000
K31.9 Disease of stomach and duodenum, unspecified	0.025	0.975	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.024	0.976	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.022	0.978	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.021	0.979	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.021	0.979	0.000
Z63.7 Other stressful life events affecting family and household	0.020	0.979	0.000
F31.8 Other bipolar affective disorders	0.019	0.981	0.000
Z63 Other problems related to primary support group, including family circumstances	0.018	0.982	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.018	0.982	0.000
Z63.5 Disruption of family by separation and divorce	0.016	0.983	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.016	0.984	0.000
F31.7 Bipolar affective disorder, currently in remission	0.016	0.984	0.000
Z63.4 Disappearance and death of family member	0.016	0.984	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.014	0.986	0.000
Z63.6 Dependent relative needing care at home	0.014	0.986	0.000
Z63.9 Problem related to primary support group, unspecified	0.013	0.987	0.000
Z63.3 Absence of family member	0.013	0.987	0.000
Z63.2 Inadequate family support	0.013	0.987	0.000
Z63.1 Problems in relationship with parents and in-laws	0.013	0.987	0.000
Z63.8 Other specified problems related to primary support group	0.013	0.987	0.000
Z63.0 Problems in relationship with spouse or partner	0.012	0.988	0.000
Z57.2 Occupational exposure to dust	0.012	0.988	0.000
F30-F39 Mood [affective] disorders	0.011	0.989	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.989	0.011
G31.8 Other specified degenerative diseases of nervous system	0.000	0.990	0.010
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.990	0.010
Z57 Occupational exposure to risk-factors	0.010	0.990	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.010	0.990	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.010	0.990	0.000
F39 Unspecified mood [affective] disorder	0.009	0.991	0.000
M22.2 Patellofemoral disorders	0.000	0.991	0.009
F33.9 Recurrent depressive disorder, unspecified	0.009	0.991	0.000
F34 Persistent mood [affective] disorders	0.009	0.991	0.000
Z56 Problems related to employment and unemployment	0.009	0.991	0.000
F33 Recurrent depressive disorder	0.008	0.992	0.000
M22 Disorders of patella	0.000	0.992	0.008
G31.2 Degeneration of nervous system due to alcohol	0.000	0.992	0.008
M22.4 Chondromalacia patellae	0.000	0.992	0.008
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.992	0.008
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.992	0.008
H61.2 Impacted cerumen	0.000	0.992	0.008
F38 Other mood [affective] disorders	0.008	0.992	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.992	0.008
Z61 Problems related to negative life events in childhood	0.008	0.992	0.000
M22.8 Other disorders of patella	0.000	0.992	0.008
Z57.5 Occupational exposure to toxic agents in other industries	0.007	0.992	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.993	0.007
F34.1 Dysthymia	0.007	0.993	0.000
M22.3 Other derangements of patella	0.000	0.993	0.007
Z57.9 Occupational exposure to unspecified risk-factor	0.007	0.993	0.000
Z57.7 Occupational exposure to vibration	0.007	0.993	0.000
Z57.6 Occupational exposure to extreme temperature	0.007	0.993	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.007	0.993	0.000
Z57.1 Occupational exposure to radiation	0.007	0.993	0.000
Z57.0 Occupational exposure to noise	0.007	0.993	0.000
Z56.3 Stressful work schedule	0.007	0.993	0.000
I12.0 Hypertensive renal disease with renal failure	0.007	0.993	0.000
F30 Manic episode	0.007	0.993	0.000
Z62 Other problems related to upbringing	0.007	0.993	0.000
Z55 Problems related to education and literacy	0.007	0.993	0.000
M22.9 Disorder of patella, unspecified	0.000	0.993	0.007
G31.0 Circumscribed brain atrophy	0.000	0.993	0.007
Z56.0 Unemployment, unspecified	0.007	0.993	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.993	0.007
Z56.4 Discord with boss and workmates	0.007	0.993	0.000
Z58 Problems related to physical environment	0.007	0.993	0.000
Z56.7 Other and unspecified problems related to employment	0.007	0.993	0.000
F33.8 Other recurrent depressive disorders	0.007	0.993	0.000
F34.0 Cyclothymia	0.007	0.993	0.000
Z56.6 Other physical and mental strain related to work	0.007	0.993	0.000
Z57.3 Occupational exposure to other air contaminants	0.007	0.993	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.006	0.993	0.000
F34.8 Other persistent mood [affective] disorders	0.006	0.993	0.000
Z56.5 Uncongenial work	0.006	0.993	0.000
Z56.2 Threat of job loss	0.006	0.993	0.000
Z56.1 Change of job	0.006	0.993	0.000
S80.8 Other superficial injuries of lower leg	0.000	0.994	0.006
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.994	0.006
Z64 Problems related to certain psychosocial circumstances	0.006	0.994	0.000
M22.1 Recurrent subluxation of patella	0.000	0.994	0.006
M22.0 Recurrent dislocation of patella	0.000	0.994	0.006
Z65 Problems related to other psychosocial circumstances	0.006	0.994	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.994	0.006
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.006	0.994	0.000
Z45.2 Adjustment and management of vascular access device	0.006	0.994	0.000
K11.5 Sialolithiasis	0.000	0.994	0.006
F30.1 Mania without psychotic symptoms	0.006	0.994	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.006	0.994	0.000
F30.2 Mania with psychotic symptoms	0.006	0.994	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.006	0.994	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.994	0.006
F38.8 Other specified mood [affective] disorders	0.006	0.994	0.000
F38.1 Other recurrent mood [affective] disorders	0.006	0.994	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.006	0.994	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.006	0.994	0.000
Z61.9 Negative life events in childhood, unspecified	0.006	0.994	0.000
Z61.8 Other negative life events in childhood	0.006	0.994	0.000
Z61.7 Personal frightening experience in childhood	0.006	0.994	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.006	0.994	0.000
Z61.2 Altered pattern of family relationships in childhood	0.006	0.994	0.000
Z61.1 Removal from home in childhood	0.006	0.994	0.000
Z61.0 Loss of love relationship in childhood	0.006	0.994	0.000
F38.0 Other single mood [affective] disorders	0.005	0.994	0.000
Z57.8 Occupational exposure to other risk-factors	0.005	0.994	0.000
F30.8 Other manic episodes	0.005	0.994	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.005	0.994	0.000
Z55.8 Other problems relating to education and literacy	0.005	0.994	0.000
Z55.4 Educational maladjustment and discord with teachers and classmates	0.005	0.994	0.000
Z55.3 Underachievement in school	0.005	0.994	0.000
Z55.2 Failed examinations	0.005	0.994	0.000
Z55.1 Schooling unavailable and unattainable	0.005	0.994	0.000
Z55.0 Illiteracy and low-level literacy	0.005	0.994	0.000
Z61.6 Problems related to alleged physical abuse of child	0.005	0.994	0.000
Z62.9 Problem related to upbringing, unspecified	0.005	0.994	0.000
Z62.8 Other specified problems related to upbringing	0.005	0.994	0.000
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.005	0.994	0.000
Z62.5 Other problems related to neglect in upbringing	0.005	0.994	0.000
Z62.4 Emotional neglect of child	0.005	0.994	0.000
Z62.3 Hostility towards and scapegoating of child	0.005	0.994	0.000
Z62.2 Institutional upbringing	0.005	0.994	0.000
Z62.1 Parental overprotection	0.005	0.994	0.000
Z62.0 Inadequate parental supervision and control	0.005	0.994	0.000
Z58.1 Exposure to air pollution	0.005	0.995	0.000
Z58.7 Exposure to tobacco smoke	0.005	0.995	0.000
Z58.9 Problem related to physical environment, unspecified	0.005	0.995	0.000
Z58.6 Inadequate drinking-water supply	0.005	0.995	0.000
Z58.4 Exposure to radiation	0.005	0.995	0.000
Z58.3 Exposure to soil pollution	0.005	0.995	0.000
Z58.2 Exposure to water pollution	0.005	0.995	0.000
Z58.0 Exposure to noise	0.005	0.995	0.000
F30.0 Hypomania	0.005	0.995	0.000
Z59 Problems related to housing and economic circumstances	0.005	0.995	0.000
O70.9 Perineal laceration during delivery, unspecified	0.005	0.995	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.005	0.995	0.000
S62.50 Fracture of thumb (closed)	0.000	0.995	0.005
K11.8 Other diseases of salivary glands	0.000	0.995	0.005
Z60 Problems related to social environment	0.005	0.995	0.000
Z65.3 Problems related to other legal circumstances	0.005	0.995	0.000
Z64.4 Discord with counsellors	0.005	0.995	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.005	0.995	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.005	0.995	0.000
Z64.1 Problems related to multiparity	0.005	0.995	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.000	0.995	0.005
Z58.8 Other problems related to physical environment	0.005	0.995	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.005	0.995	0.000
Z65.5 Exposure to disaster, war and other hostilities	0.005	0.995	0.000
Z65.4 Victim of crime and terrorism	0.005	0.995	0.000
Z65.2 Problems related to release from prison	0.005	0.995	0.000
Z65.1 Imprisonment and other incarceration	0.005	0.995	0.000
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.005	0.995	0.000
Z58.5 Exposure to other pollution	0.004	0.995	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.004	0.995	0.000
K11 Diseases of salivary glands	0.000	0.996	0.004
D46.9 Myelodysplastic syndrome, unspecified	0.004	0.996	0.000
D07.5 Prostate	0.004	0.996	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.000	0.996	0.004
Z60.8 Other problems related to social environment	0.004	0.996	0.000
R63.8 Other symptoms and signs concerning food and fluid intake	0.000	0.996	0.004
Z59.2 Discord with neighbours, lodgers and landlord	0.004	0.996	0.000
Z59.7 Insufficient social insurance and welfare support	0.004	0.996	0.000
Z59.6 Low income	0.004	0.996	0.000
Z59.5 Extreme poverty	0.004	0.996	0.000
Z59.3 Problems related to living in residential institution	0.004	0.996	0.000
K11.6 Mucocele of salivary gland	0.000	0.996	0.004
Z64.0 Problems related to unwanted pregnancy	0.004	0.996	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.000	0.996	0.004
Z65.8 Other specified problems related to psychosocial circumstances	0.003	0.996	0.000
Z59.4 Lack of adequate food	0.004	0.996	0.000
Z60.5 Target of perceived adverse discrimination and persecution	0.004	0.996	0.000
Z60.4 Social exclusion and rejection	0.004	0.996	0.000
Z60.3 Acculturation difficulty	0.004	0.996	0.000
Z60.1 Atypical parenting situation	0.004	0.996	0.000
Z60.0 Problems of adjustment to life-cycle transitions	0.004	0.996	0.000
Z59.0 Homelessness	0.004	0.996	0.000
Z60.9 Problem related to social environment, unspecified	0.004	0.996	0.000
Z59.8 Other problems relating to housing and economic circumstances	0.004	0.996	0.000
F30.9 Manic episode, unspecified	0.003	0.996	0.000
S62.5 Fracture of thumb	0.000	0.996	0.004
Y84.8 Other medical procedures	0.004	0.996	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.996	0.003
T79.8 Other early complications of trauma	0.000	0.996	0.004
T79.6 Traumatic ischaemia of muscle	0.000	0.996	0.004
L60.8 Other nail disorders	0.000	0.996	0.004
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.003	0.996	0.000
O70.2 Third degree perineal laceration during delivery	0.004	0.996	0.000
K11.3 Abscess of salivary gland	0.000	0.996	0.003
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.996	0.004
K50.9 Crohn's disease, unspecified	0.000	0.997	0.003
K11.4 Fistula of salivary gland	0.000	0.997	0.003
K11.0 Atrophy of salivary gland	0.000	0.997	0.003
R44.3 Hallucinations, unspecified	0.000	0.997	0.003
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.997	0.003
Z59.1 Inadequate housing	0.003	0.997	0.000
T79.7 Traumatic subcutaneous emphysema	0.000	0.997	0.003
K11.7 Disturbances of salivary secretion	0.000	0.997	0.003
T79.5 Traumatic anuria	0.000	0.997	0.003
K11.2 Sialoadenitis	0.000	0.997	0.003
H66.3 Other chronic suppurative otitis media	0.000	0.997	0.003
H61 Other disorders of external ear	0.000	0.997	0.003
F32 Depressive episode	0.003	0.997	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.003	0.997	0.000
O70 Perineal laceration during delivery	0.003	0.997	0.000
T79.9 Unspecified early complication of trauma	0.000	0.997	0.003
T79.1 Fat embolism (traumatic)	0.000	0.997	0.003
T79.0 Air embolism (traumatic)	0.000	0.997	0.003
D07 Carcinoma in situ of other and unspecified genital organs	0.003	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.000	0.997	0.003
S62.51 Fracture of thumb (open)	0.000	0.997	0.003
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.000	0.997	0.003
K11.9 Disease of salivary gland, unspecified	0.000	0.997	0.003
S42.40 Fracture of lower end of humerus (closed)	0.000	0.997	0.003
H66.9 Otitis media, unspecified	0.000	0.997	0.003
T79.4 Traumatic shock	0.000	0.997	0.003
K11.1 Hypertrophy of salivary gland	0.000	0.997	0.003
D07.1 Vulva	0.003	0.997	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.000	0.997	0.003
D46 Myelodysplastic syndromes	0.003	0.997	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.003	0.997	0.000
O70.3 Fourth degree perineal laceration during delivery	0.003	0.997	0.000
Q76.1 Klippel-Feil syndrome	0.000	0.997	0.003
S60.9 Superficial injury of wrist and hand, unspecified	0.003	0.997	0.000
H60.4 Cholesteatoma of external ear	0.000	0.997	0.003
H61.3 Acquired stenosis of external ear canal	0.000	0.997	0.003
R22.9 Localised swelling, mass and lump, unspecified	0.003	0.997	0.000
R23.8 Other and unspecified skin changes	0.003	0.997	0.000
F32.0 Mild depressive episode	0.003	0.997	0.000
Q76.5 Cervical rib	0.000	0.997	0.003
T79.2 Traumatic secondary and recurrent haemorrhage	0.000	0.997	0.003
H34.8 Other retinal vascular occlusions	0.000	0.997	0.003
D46.2 Refractory anaemia with excess of blasts	0.003	0.997	0.000
Q76.0 Spina bifida occulta	0.000	0.997	0.003
H61.9 Disorder of external ear, unspecified	0.000	0.997	0.003
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.003	0.997	0.000
I12 Hypertensive renal disease	0.003	0.997	0.000
D07.0 Endometrium	0.003	0.997	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.000	0.997	0.003
R22.7 Localised swelling, mass and lump, multiple sites	0.003	0.997	0.000
R23.3 Spontaneous ecchymoses	0.003	0.997	0.000
D07.4 Penis	0.002	0.997	0.000
H60.3 Other infective otitis externa	0.000	0.997	0.003
H60 Otitis externa	0.000	0.997	0.003
F32.8 Other depressive episodes	0.002	0.997	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.003	0.997	0.000
D07.2 Vagina	0.002	0.997	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.002	0.997	0.000
D07.6 Other and unspecified male genital organs	0.002	0.998	0.000
D07.3 Other and unspecified female genital organs	0.002	0.998	0.000
D46.4 Refractory anaemia, unspecified	0.002	0.998	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.000	0.998	0.002
Q76.8 Other congenital malformations of bony thorax	0.000	0.998	0.002
Q76.7 Congenital malformation of sternum	0.000	0.998	0.002
Q76.6 Other congenital malformations of ribs	0.000	0.998	0.002
Q76.3 Congenital scoliosis due to congenital bony malformation	0.000	0.998	0.002
Q76.2 Congenital spondylolisthesis	0.000	0.998	0.002
S62 Fracture at wrist and hand level	0.000	0.998	0.002
J38.3 Other diseases of vocal cords	0.002	0.998	0.000
S80.7 Multiple superficial injuries of lower leg	0.000	0.998	0.002
S80 Superficial injury of lower leg	0.000	0.998	0.002
D46.0 Refractory anaemia without sideroblasts, so stated	0.002	0.998	0.000
R44.0 Auditory hallucinations	0.000	0.998	0.002
D46.7 Other myelodysplastic syndromes	0.002	0.998	0.000
O70.0 First degree perineal laceration during delivery	0.002	0.998	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.000	0.998	0.002
D22.4 Melanocytic naevi of scalp and neck	0.000	0.998	0.002
H60.0 Abscess of external ear	0.000	0.998	0.002
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.998	0.002
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.000	0.998	0.002
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.002	0.998	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.002	0.998	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.998	0.002
R22.4 Localised swelling, mass and lump, lower limb	0.002	0.998	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.998	0.002
D47.1 Chronic myeloproliferative disease	0.002	0.998	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.002	0.998	0.000
S62.1 Fracture of other carpal bone(s)	0.000	0.998	0.002
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.000	0.998	0.002
K70.0 Alcoholic fatty liver	0.000	0.998	0.002
O02.1 Missed abortion	0.002	0.998	0.000
H60.2 Malignant otitis externa	0.000	0.998	0.002
H61.8 Other specified disorders of external ear	0.000	0.998	0.002
R22.0 Localised swelling, mass and lump, head	0.002	0.998	0.000
H60.5 Acute otitis externa, non-infective	0.000	0.998	0.002
H66 Suppurative and unspecified otitis media	0.000	0.998	0.002
H60-H62 Diseases of external ear	0.000	0.998	0.002
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.998	0.002
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.998	0.002
S62.10 Fracture of other carpal bone(s) (closed)	0.000	0.998	0.002
S80.0 Contusion of knee	0.000	0.998	0.002
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.000	0.998	0.002
F52.2 Failure of genital response	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.000	0.998	0.002
M06 Other rheumatoid arthritis	0.000	0.998	0.002
R23 Other skin changes	0.002	0.998	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.998	0.002
Q79.6 Ehlers-Danlos syndrome	0.000	0.998	0.002
Z75.5 Holiday relief care	0.000	0.998	0.002
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.998	0.002
D46.1 Refractory anaemia with sideroblasts	0.002	0.998	0.000
H60.8 Other otitis externa	0.000	0.998	0.002
S62.7 Multiple fractures of fingers	0.000	0.998	0.002
Z75.8 Other problems related to medical facilities and other health care	0.000	0.998	0.002
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.000	0.998	0.002
Z75.1 Person awaiting admission to adequate facility elsewhere	0.000	0.998	0.002
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.998	0.002
Z75.2 Other waiting period for investigation and treatment	0.000	0.998	0.002
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.998	0.002
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.002	0.998	0.000
Z75.0 Medical services not available in home	0.000	0.998	0.002
Q65 Congenital deformities of hip	0.000	0.998	0.002
Z75 Problems related to medical facilities and other health care	0.000	0.998	0.002
S62.71 Multiple fractures of fingers (open)	0.000	0.998	0.002
F32.3 Severe depressive episode with psychotic symptoms	0.002	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.998	0.002
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.998	0.002
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
R47.1 Dysarthria and anarthria	0.000	0.998	0.002
S42.4 Fracture of lower end of humerus	0.000	0.998	0.002
S62.4 Multiple fractures of metacarpal bones	0.000	0.998	0.002
S62.3 Fracture of other metacarpal bone	0.000	0.998	0.002
S62.2 Fracture of first metacarpal bone	0.000	0.998	0.002
Q74 Other congenital malformations of limb(s)	0.000	0.998	0.002
S62.11 Fracture of other carpal bone(s) (open)	0.000	0.998	0.002
S72.40 Fracture of lower end of femur (closed)	0.002	0.998	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.000	0.998	0.002
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.000	0.998	0.002
Q79.5 Other congenital malformations of abdominal wall	0.000	0.998	0.002
Q79.4 Prune belly syndrome	0.000	0.998	0.002
Q79.3 Gastroschisis	0.000	0.998	0.002
Q79.2 Exomphalos	0.000	0.998	0.002
Q79.0 Congenital diaphragmatic hernia	0.000	0.998	0.002
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.002	0.998	0.000
H50.1 Divergent concomitant strabismus	0.000	0.998	0.002
Q70 Syndactyly	0.000	0.998	0.002
H34.2 Other retinal artery occlusions	0.000	0.998	0.002
Q67.6 Pectus excavatum	0.000	0.998	0.002
H34 Retinal vascular occlusions	0.000	0.998	0.002
Q75 Other congenital malformations of skull and face bones	0.000	0.998	0.002
Q73 Reduction defects of unspecified limb	0.000	0.998	0.002
Q72 Reduction defects of lower limb	0.000	0.998	0.002
Q71 Reduction defects of upper limb	0.000	0.998	0.002
Q69 Polydactyly	0.000	0.998	0.002
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.998	0.002
M06.2 Rheumatoid bursitis	0.000	0.998	0.002
Q65.1 Congenital dislocation of hip, bilateral	0.000	0.998	0.002
H61.1 Non-infective disorders of pinna	0.000	0.998	0.002
M06.1 Adult-onset Still's disease	0.000	0.998	0.002
Q67.8 Other congenital deformities of chest	0.000	0.998	0.002
Q67.7 Pectus carinatum	0.000	0.998	0.002
Q67.3 Plagiocephaly	0.000	0.998	0.002
Q67.2 Dolichocephaly	0.000	0.998	0.002
Q67.1 Compression facies	0.000	0.998	0.002
Q67.0 Facial asymmetry	0.000	0.998	0.002
S42.41 Fracture of lower end of humerus (open)	0.000	0.998	0.002
H66.4 Suppurative otitis media, unspecified	0.000	0.998	0.002
Q65.8 Other congenital deformities of hip	0.000	0.998	0.002
Q79.1 Other congenital malformations of diaphragm	0.000	0.998	0.002
C10.9 Oropharynx, unspecified	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.000	0.998	0.002
H34.9 Retinal vascular occlusion, unspecified	0.000	0.998	0.002
J15.2 Pneumonia due to staphylococcus	0.000	0.998	0.002
Y04.8 Other specified place	0.000	0.998	0.002
S02.50 Fracture of tooth (closed)	0.002	0.998	0.000
S32.40 Fracture of acetabulum (closed)	0.002	0.998	0.000
H66.0 Acute suppurative otitis media	0.000	0.998	0.002
M06.8 Other specified rheumatoid arthritis	0.000	0.998	0.002
Q65.2 Congenital dislocation of hip, unspecified	0.000	0.998	0.002
S69.9 Unspecified injury of wrist and hand	0.000	0.998	0.002
Q78 Other osteochondrodysplasias	0.000	0.998	0.002
R44 Other symptoms and signs involving general sensations and perceptions	0.000	0.998	0.002
K22.8 Other specified diseases of oesophagus	0.000	0.998	0.002
Q65.9 Congenital deformity of hip, unspecified	0.000	0.998	0.002
Q65.6 Unstable hip	0.000	0.998	0.002
Q65.5 Congenital subluxation of hip, unspecified	0.000	0.998	0.002
Q65.4 Congenital subluxation of hip, bilateral	0.000	0.998	0.002
Q65.3 Congenital subluxation of hip, unilateral	0.000	0.998	0.002
Q65.0 Congenital dislocation of hip, unilateral	0.000	0.998	0.002
Z75.9 Unspecified problem related to medical facilities and other health care	0.000	0.998	0.002
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.998	0.002
K31.6 Fistula of stomach and duodenum	0.002	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.000	0.998	0.002
G30-G32 Other degenerative diseases of the nervous system	0.000	0.998	0.002
D37.4 Colon	0.002	0.998	0.000
S62.6 Fracture of other finger	0.000	0.998	0.002
T79-T79 Certain early complications of trauma	0.000	0.998	0.002
S62.21 Fracture of first metacarpal bone (open)	0.000	0.998	0.001
S62.41 Multiple fractures of metacarpal bones (open)	0.000	0.998	0.001
F32.1 Moderate depressive episode	0.002	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.000	0.998	0.001
Q70.3 Webbed toes	0.000	0.998	0.001
Q74.9 Unspecified congenital malformation of limb(s)	0.000	0.998	0.001
Q74.8 Other specified congenital malformations of limb(s)	0.000	0.998	0.001
Q74.3 Arthrogryposis multiplex congenita	0.000	0.998	0.001
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.000	0.998	0.002
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.000	0.998	0.002
S62.31 Fracture of other metacarpal bone (open)	0.000	0.998	0.002
I12.9 Hypertensive renal disease without renal failure	0.002	0.998	0.000
Q74.1 Congenital malformation of knee	0.000	0.998	0.001
S62.8 Fracture of other and unspecified parts of wrist and hand	0.000	0.998	0.002
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.002	0.998	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.002	0.998	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.002	0.998	0.000
Q70.9 Syndactyly, unspecified	0.000	0.998	0.001
Q70.4 Polysyndactyly	0.000	0.998	0.001
Q70.2 Fused toes	0.000	0.998	0.001
Q70.1 Webbed fingers	0.000	0.998	0.001
Q70.0 Fused fingers	0.000	0.998	0.001
T92.0 Sequelae of open wound of upper limb	0.000	0.998	0.002
Z45.1 Adjustment and management of infusion pump	0.002	0.998	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.998	0.001
K31 Other diseases of stomach and duodenum	0.002	0.998	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.998	0.002
S62.70 Multiple fractures of fingers (closed)	0.000	0.998	0.001
H34.0 Transient retinal artery occlusion	0.000	0.998	0.001
M06.3 Rheumatoid nodule	0.000	0.998	0.002
Q69.9 Polydactyly, unspecified	0.000	0.998	0.001
Q69.2 Accessory toe(s)	0.000	0.998	0.001
Q69.1 Accessory thumb(s)	0.000	0.998	0.001
Q69.0 Accessory finger(s)	0.000	0.998	0.001
Q71.9 Reduction defect of upper limb, unspecified	0.000	0.998	0.001
Q71.8 Other reduction defects of upper limb(s)	0.000	0.998	0.001
Q71.6 Lobster-claw hand	0.000	0.998	0.001
Q71.5 Longitudinal reduction defect of ulna	0.000	0.998	0.001
Q71.4 Longitudinal reduction defect of radius	0.000	0.998	0.001
Q71.3 Congenital absence of hand and finger(s)	0.000	0.998	0.001
Q71.2 Congenital absence of both forearm and hand	0.000	0.998	0.001
Q71.1 Congenital absence of upper arm and forearm with hand present	0.000	0.998	0.001
Q71.0 Congenital complete absence of upper limb(s)	0.000	0.998	0.001
Q72.9 Reduction defect of lower limb, unspecified	0.000	0.998	0.001
Q72.8 Other reduction defects of lower limb(s)	0.000	0.998	0.001
Q72.7 Split foot	0.000	0.998	0.001
Q72.6 Longitudinal reduction defect of fibula	0.000	0.998	0.001
Q72.5 Longitudinal reduction defect of tibia	0.000	0.998	0.001
Q72.4 Longitudinal reduction defect of femur	0.000	0.998	0.001
Q72.3 Congenital absence of foot and toe(s)	0.000	0.998	0.001
Q72.2 Congenital absence of both lower leg and foot	0.000	0.998	0.001
Q72.1 Congenital absence of thigh and lower leg with foot present	0.000	0.998	0.001
Q72.0 Congenital complete absence of lower limb(s)	0.000	0.998	0.001
Q73.8 Other reduction defects of unspecified limb(s)	0.000	0.998	0.001
Q73.1 Phocomelia, unspecified limb(s)	0.000	0.998	0.001
Q73.0 Congenital absence of unspecified limb(s)	0.000	0.998	0.001
Q75.9 Congenital malformation of skull and face bones, unspecified	0.000	0.998	0.001
Q75.8 Other specified congenital malformations of skull and face bones	0.000	0.998	0.001
Q75.5 Oculomandibular dysostosis	0.000	0.998	0.001
Q75.4 Mandibulofacial dysostosis	0.000	0.998	0.001
Q75.3 Macrocephaly	0.000	0.998	0.001
Q75.2 Hypertelorism	0.000	0.998	0.001
Q75.1 Craniofacial dysostosis	0.000	0.998	0.001
Q75.0 Craniosynostosis	0.000	0.998	0.001
R23.2 Flushing	0.002	0.998	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.998	0.001
M06.28 Rheumatoid bursitis (Other)	0.000	0.998	0.001
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.998	0.001
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.998	0.001
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.998	0.001
M06.24 Rheumatoid bursitis (Hand)	0.000	0.998	0.001
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.998	0.001
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.998	0.001
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.998	0.001
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.998	0.001
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.998	0.001
M06.18 Adult-onset Still's disease (Other)	0.000	0.998	0.001
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.998	0.001
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.998	0.001
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.998	0.001
M06.14 Adult-onset Still's disease (Hand)	0.000	0.998	0.001
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.998	0.001
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.998	0.001
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.998	0.001
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.998	0.001
K31.3 Pylorospasm, not elsewhere classified	0.001	0.998	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.000	0.998	0.001
Q68.4 Congenital bowing of tibia and fibula	0.000	0.998	0.001
Q68.3 Congenital bowing of femur	0.000	0.998	0.001
Q68.2 Congenital deformity of knee	0.000	0.998	0.001
Q68.1 Congenital deformity of hand	0.000	0.998	0.001
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.000	0.998	0.001
K50 Crohn's disease [regional enteritis]	0.000	0.998	0.002
S62.40 Multiple fractures of metacarpal bones (closed)	0.000	0.998	0.001
M06.4 Inflammatory polyarthropathy	0.000	0.998	0.001
Q66.7 Pes cavus	0.000	0.998	0.001
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.998	0.001
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.998	0.001
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.998	0.001
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.998	0.001
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.998	0.001
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.998	0.001
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.998	0.001
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.998	0.001
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.998	0.001
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.998	0.001
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.998	0.001
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.998	0.001
S72.00 Fracture of neck of femur (closed)	0.002	0.998	0.000
F10.3 Withdrawal state	0.000	0.998	0.002
I82.2 Embolism and thrombosis of vena cava	0.000	0.998	0.001
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.998	0.001
Q78.9 Osteochondrodysplasia, unspecified	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations