TreeWAS – Variant ID: rs9401593

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G20 Parkinson's disease	0.133	0.867	0.000
S01.8 Open wound of other parts of head	0.033	0.967	0.000
R22.2 Localised swelling, mass and lump, trunk	0.000	0.967	0.033
S01.2 Open wound of nose	0.025	0.975	0.000
S01 Open wound of head	0.021	0.979	0.000
I73.9 Peripheral vascular disease, unspecified	0.000	0.980	0.020
F31 Bipolar affective disorder	0.017	0.983	0.000
S01.4 Open wound of cheek and temporomandibular area	0.016	0.984	0.000
Z22.3 Carrier of other specified bacterial diseases	0.000	0.984	0.016
G20-G26 Extrapyramidal and movement disorders	0.015	0.984	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.015	0.985	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.015	0.985	0.000
S02.60 Fracture of mandible (closed)	0.015	0.985	0.000
S01.3 Open wound of ear	0.015	0.985	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.015	0.985	0.000
F31.9 Bipolar affective disorder, unspecified	0.015	0.985	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.015	0.985	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.015	0.985	0.000
S01.1 Open wound of eyelid and periocular area	0.014	0.986	0.000
S02.6 Fracture of mandible	0.014	0.986	0.000
F31.7 Bipolar affective disorder, currently in remission	0.014	0.986	0.000
S02 Fracture of skull and facial bones	0.014	0.986	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.014	0.986	0.000
F31.8 Other bipolar affective disorders	0.013	0.987	0.000
G21 Secondary Parkinsonism	0.013	0.987	0.000
S00-S09 Injuries to the head	0.013	0.987	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.012	0.988	0.000
S02.0 Fracture of vault of skull	0.012	0.988	0.000
N20.2 Calculus of kidney with calculus of ureter	0.000	0.988	0.012
S02.5 Fracture of tooth	0.012	0.988	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.011	0.988	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.011	0.989	0.000
G22 Parkinsonism in diseases classified elsewhere	0.011	0.989	0.000
S01.5 Open wound of lip and oral cavity	0.011	0.989	0.000
S02.8 Fractures of other skull and facial bones	0.011	0.989	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.011	0.989	0.000
G23 Other degenerative diseases of basal ganglia	0.011	0.989	0.000
S02.00 Fracture of vault of skull (closed)	0.011	0.989	0.000
S02.61 Fracture of mandible (open)	0.010	0.989	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.010	0.990	0.000
G21.9 Secondary Parkinsonism, unspecified	0.010	0.990	0.000
G21.0 Malignant neuroleptic syndrome	0.010	0.990	0.000
S02.3 Fracture of orbital floor	0.010	0.990	0.000
S02.7 Multiple fractures involving skull and facial bones	0.010	0.990	0.000
S02.50 Fracture of tooth (closed)	0.010	0.990	0.000
S06 Intracranial injury	0.010	0.990	0.000
G21.8 Other secondary Parkinsonism	0.009	0.990	0.000
G21.4 Vascular parkinsonism	0.009	0.990	0.000
G21.3 Postencephalitic Parkinsonism	0.009	0.990	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.009	0.990	0.000
S07 Crushing injury of head	0.009	0.991	0.000
S04 Injury of cranial nerves	0.009	0.991	0.000
S08 Traumatic amputation of part of head	0.009	0.991	0.000
I73 Other peripheral vascular diseases	0.000	0.991	0.009
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.009	0.991	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.009	0.991	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.009	0.991	0.000
S03.2 Dislocation of tooth	0.009	0.991	0.000
S02.01 Fracture of vault of skull (open)	0.009	0.991	0.000
S05 Injury of eye and orbit	0.009	0.991	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.009	0.991	0.000
S03.1 Dislocation of septal cartilage of nose	0.009	0.991	0.000
S03.0 Dislocation of jaw	0.009	0.991	0.000
S02.51 Fracture of tooth (open)	0.008	0.991	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.009	0.991	0.000
S01.0 Open wound of scalp	0.009	0.991	0.000
I73.8 Other specified peripheral vascular diseases	0.000	0.991	0.008
S02.2 Fracture of nasal bones	0.008	0.992	0.000
S06.0 Concussion	0.008	0.992	0.000
S02.81 Fractures of other skull and facial bones (open)	0.008	0.992	0.000
S06.2 Diffuse brain injury	0.008	0.992	0.000
S02.4 Fracture of malar and maxillary bones	0.008	0.992	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.008	0.992	0.000
S03.4 Sprain and strain of jaw	0.008	0.992	0.000
S03.3 Dislocation of other and unspecified parts of head	0.008	0.992	0.000
F30 Manic episode	0.008	0.992	0.000
I60 Subarachnoid haemorrhage	0.008	0.992	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.992	0.008
F30.0 Hypomania	0.008	0.992	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.008	0.992	0.000
G23.3 Multiple system atrophy, cerebellar type	0.008	0.992	0.000
G23.2 Striatonigral degeneration	0.008	0.992	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.008	0.992	0.000
G23.0 Hallervorden-Spatz disease	0.008	0.992	0.000
I60.8 Other subarachnoid haemorrhage	0.008	0.992	0.000
S02.1 Fracture of base of skull	0.008	0.992	0.000
M10.9 Gout, unspecified	0.000	0.992	0.008
S06.1 Traumatic cerebral oedema	0.008	0.992	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.008	0.992	0.000
S02.31 Fracture of orbital floor (open)	0.007	0.992	0.000
S02.30 Fracture of orbital floor (closed)	0.007	0.992	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.007	0.992	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.007	0.992	0.000
S06.7 Intracranial injury with prolonged coma	0.007	0.992	0.000
S06.5 Traumatic subdural haemorrhage	0.007	0.993	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.007	0.993	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.007	0.993	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.007	0.993	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.993	0.007
M10.90 Gout, unspecified (Multiple sites)	0.000	0.993	0.007
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.993	0.007
S06.9 Intracranial injury, unspecified	0.007	0.993	0.000
F30.1 Mania without psychotic symptoms	0.007	0.993	0.000
S06.4 Epidural haemorrhage	0.007	0.993	0.000
S01.7 Multiple open wounds of head	0.007	0.993	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.993	0.007
F30.2 Mania with psychotic symptoms	0.007	0.993	0.000
S06.8 Other intracranial injuries	0.007	0.993	0.000
M10.99 Gout, unspecified (Site unspecified)	0.000	0.993	0.007
S05.6 Penetrating wound of eyeball without foreign body	0.007	0.993	0.000
S06.00 Concussion (without open intracranial wound)	0.007	0.993	0.000
Y52 Agents primarily affecting the cardiovascular system	0.000	0.993	0.007
I60.9 Subarachnoid haemorrhage, unspecified	0.007	0.993	0.000
S05.9 Injury of eye and orbit, part unspecified	0.007	0.993	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.007	0.993	0.000
S04.9 Injury of unspecified cranial nerve	0.007	0.993	0.000
S04.8 Injury of other cranial nerves	0.007	0.993	0.000
S04.7 Injury of accessory nerve	0.007	0.993	0.000
S04.6 Injury of acoustic nerve	0.007	0.993	0.000
S04.5 Injury of facial nerve	0.007	0.993	0.000
S04.4 Injury of abducent nerve	0.007	0.993	0.000
S04.3 Injury of trigeminal nerve	0.007	0.993	0.000
S04.2 Injury of trochlear nerve	0.007	0.993	0.000
S04.1 Injury of oculomotor nerve	0.007	0.993	0.000
S04.0 Injury of optic nerve and pathways	0.007	0.993	0.000
S07.9 Crushing injury of head, part unspecified	0.007	0.993	0.000
S07.8 Crushing injury of other parts of head	0.007	0.993	0.000
S07.1 Crushing injury of skull	0.007	0.993	0.000
S07.0 Crushing injury of face	0.007	0.993	0.000
S08.9 Traumatic amputation of unspecified part of head	0.007	0.993	0.000
S08.8 Traumatic amputation of other parts of head	0.007	0.993	0.000
S08.0 Avulsion of scalp	0.007	0.993	0.000
F30-F39 Mood [affective] disorders	0.007	0.993	0.000
S08.1 Traumatic amputation of ear	0.007	0.993	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.007	0.993	0.000
D05.1 Intraductal carcinoma in situ	0.007	0.993	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.007	0.993	0.000
N60.2 Fibroadenosis of breast	0.000	0.993	0.007
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.007	0.993	0.000
M10.93 Gout, unspecified (Forearm)	0.000	0.993	0.007
S05.7 Avulsion of eye	0.006	0.993	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.006	0.993	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.006	0.993	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.994	0.006
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.006	0.994	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.006	0.994	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.994	0.006
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.994	0.006
S06.01 Concussion (with open intracranial wound)	0.006	0.994	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.006	0.994	0.000
S02.21 Fracture of nasal bones (open)	0.006	0.994	0.000
F30.9 Manic episode, unspecified	0.006	0.994	0.000
F30.8 Other manic episodes	0.006	0.994	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.006	0.994	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.006	0.994	0.000
S02.11 Fracture of base of skull (open)	0.006	0.994	0.000
M10.92 Gout, unspecified (Upper arm)	0.000	0.994	0.006
Y52.1 Calcium-channel blockers	0.000	0.994	0.006
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.006	0.994	0.000
Z22 Carrier of infectious disease	0.000	0.994	0.006
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.006	0.994	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.006	0.994	0.000
M10.94 Gout, unspecified (Hand)	0.000	0.994	0.006
M10.98 Gout, unspecified (Other)	0.000	0.994	0.006
M10.95 Gout, unspecified (Pelvic region and thigh)	0.000	0.994	0.006
M10.91 Gout, unspecified (Shoulder region)	0.000	0.994	0.006
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.006	0.994	0.000
F39 Unspecified mood [affective] disorder	0.006	0.994	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.000	0.994	0.006
D52.9 Folate deficiency anaemia, unspecified	0.000	0.994	0.006
S05.8 Other injuries of eye and orbit	0.006	0.994	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.005	0.994	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.005	0.994	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.005	0.994	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.000	0.994	0.006
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.006	0.994	0.000
S06.3 Focal brain injury	0.005	0.994	0.001
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.005	0.995	0.000
H50.0 Convergent concomitant strabismus	0.005	0.995	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.005	0.995	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.005	0.995	0.000
Y52.7 Peripheral vasodilators	0.000	0.995	0.005
Y52.8 Antivaricose drugs, including sclerosing agents	0.000	0.995	0.005
I60.4 Subarachnoid haemorrhage from basilar artery	0.005	0.995	0.000
Z22.1 Carrier of other intestinal infectious diseases	0.000	0.995	0.005
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.995	0.005
F38 Other mood [affective] disorders	0.005	0.995	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.005	0.995	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.005	0.995	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.995	0.005
S06.40 Epidural haemorrhage (without open intracranial wound)	0.005	0.995	0.000
F34 Persistent mood [affective] disorders	0.005	0.995	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.005	0.995	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.005	0.995	0.000
U80.1 Methicillin resistant agent	0.000	0.995	0.005
M10.96 Gout, unspecified (Lower leg)	0.000	0.995	0.005
G55.0 Nerve root and plexus compressions in neoplastic disease	0.005	0.995	0.000
K42.9 Umbilical hernia without obstruction or gangrene	0.000	0.995	0.005
G55.3 Nerve root and plexus compressions in other dorsopathies	0.005	0.995	0.000
I73.0 Raynaud's syndrome	0.000	0.995	0.005
Q79.6 Ehlers-Danlos syndrome	0.005	0.995	0.000
Z22.9 Carrier of infectious disease, unspecified	0.000	0.995	0.004
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.000	0.995	0.004
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.000	0.995	0.004
Z22.2 Carrier of diphtheria	0.000	0.995	0.004
Z22.0 Carrier of typhoid	0.000	0.995	0.004
Z99.3 Dependence on wheelchair	0.000	0.995	0.005
G24 Dystonia	0.004	0.996	0.001
T78 Adverse effects, not elsewhere classified	0.000	0.996	0.004
S05.1 Contusion of eyeball and orbital tissues	0.004	0.996	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.004	0.996	0.000
Q23.1 Congenital insufficiency of aortic valve	0.000	0.996	0.004
S02.20 Fracture of nasal bones (closed)	0.004	0.996	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.004	0.996	0.001
T78.3 Angioneurotic oedema	0.000	0.996	0.004
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.996	0.004
S02.40 Fracture of malar and maxillary bones (closed)	0.004	0.996	0.000
F38.8 Other specified mood [affective] disorders	0.004	0.996	0.000
F38.1 Other recurrent mood [affective] disorders	0.004	0.996	0.000
F34.0 Cyclothymia	0.004	0.996	0.000
F38.0 Other single mood [affective] disorders	0.004	0.996	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.996	0.004
Z22.8 Carrier of other infectious diseases	0.000	0.996	0.004
F34.9 Persistent mood [affective] disorder, unspecified	0.004	0.996	0.000
F34.8 Other persistent mood [affective] disorders	0.004	0.996	0.000
L81.4 Other melanin hyperpigmentation	0.000	0.996	0.004
G63.2 Diabetic polyneuropathy	0.000	0.996	0.004
G24.0 Drug-induced dystonia	0.003	0.996	0.001
D86.9 Sarcoidosis, unspecified	0.000	0.996	0.004
S09 Other and unspecified injuries of head	0.003	0.996	0.000
F34.1 Dysthymia	0.003	0.997	0.000
G24.4 Idiopathic orofacial dystonia	0.003	0.997	0.001
G24.2 Idiopathic nonfamilial dystonia	0.003	0.997	0.001
G24.1 Idiopathic familial dystonia	0.003	0.997	0.001
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.997	0.003
T78.9 Adverse effect, unspecified	0.000	0.997	0.003
D86 Sarcoidosis	0.000	0.997	0.003
N17.9 Acute renal failure, unspecified	0.000	0.997	0.003
H65.0 Acute serous otitis media	0.000	0.997	0.003
H93.1 Tinnitus	0.000	0.997	0.003
I84.4 External haemorrhoids with other complications	0.000	0.997	0.003
S61.1 Open wound of finger(s) with damage to nail	0.000	0.997	0.003
D86.0 Sarcoidosis of lung	0.000	0.997	0.003
E78.5 Hyperlipidaemia, unspecified	0.000	0.997	0.003
D86.1 Sarcoidosis of lymph nodes	0.000	0.997	0.003
H65 Nonsuppurative otitis media	0.000	0.997	0.003
S01.9 Open wound of head, part unspecified	0.002	0.997	0.001
M10 Gout	0.000	0.997	0.003
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.003	0.997	0.000
Z22.5 Carrier of viral hepatitis	0.000	0.997	0.003
G25 Other extrapyramidal and movement disorders	0.003	0.997	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.997	0.003
D86.8 Sarcoidosis of other and combined sites	0.000	0.997	0.003
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.003	0.997	0.000
S02.10 Fracture of base of skull (closed)	0.003	0.997	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.003	0.997	0.000
M66.3 Spontaneous rupture of flexor tendons	0.003	0.997	0.000
S09.7 Multiple injuries of head	0.003	0.997	0.000
S09.1 Injury of muscle and tendon of head	0.003	0.997	0.000
S09.2 Traumatic rupture of ear drum	0.003	0.997	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.997	0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.003	0.997	0.000
G24.3 Spasmodic torticollis	0.002	0.997	0.001
D86.3 Sarcoidosis of skin	0.000	0.997	0.003
G24.8 Other dystonia	0.002	0.997	0.001
J39.8 Other specified diseases of upper respiratory tract	0.003	0.997	0.000
Q79.0 Congenital diaphragmatic hernia	0.003	0.997	0.000
D52 Folate deficiency anaemia	0.000	0.997	0.003
G24.9 Dystonia, unspecified	0.002	0.997	0.000
G25.5 Other chorea	0.002	0.997	0.000
G24.5 Blepharospasm	0.002	0.997	0.001
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.003	0.997	0.000
T78.4 Allergy, unspecified	0.000	0.997	0.003
M66 Spontaneous rupture of synovium and tendon	0.003	0.997	0.000
M66.36 Spontaneous rupture of flexor tendons (Lower leg)	0.002	0.997	0.000
N42.9 Disorder of prostate, unspecified	0.000	0.997	0.003
D05 Carcinoma in situ of breast	0.003	0.997	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997	0.000
D05.7 Other carcinoma in situ of breast	0.003	0.997	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.001	0.997	0.001
J31.0 Chronic rhinitis	0.003	0.997	0.000
J84.8 Other specified interstitial pulmonary diseases	0.000	0.997	0.003
M66.33 Spontaneous rupture of flexor tendons (Forearm)	0.002	0.997	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.002	0.997	0.000
H65.1 Other acute nonsuppurative otitis media	0.000	0.998	0.002
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.000	0.998	0.002
H65.4 Other chronic nonsuppurative otitis media	0.000	0.998	0.002
M10.4 Other secondary gout	0.000	0.998	0.002
M10.3 Gout due to impairment of renal function	0.000	0.998	0.002
M10.2 Drug-induced gout	0.000	0.998	0.002
M10.1 Lead-induced gout	0.000	0.998	0.002
K70.2 Alcoholic fibrosis and sclerosis of liver	0.002	0.998	0.000
K70.0 Alcoholic fatty liver	0.002	0.998	0.000
M66.0 Rupture of popliteal cyst	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.998	0.002
G25.6 Drug-induced tics and other tics of organic origin	0.002	0.998	0.000
G25.4 Drug-induced chorea	0.002	0.998	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
T78.8 Other adverse effects, not elsewhere classified	0.001	0.998	0.002
M66.06 Rupture of popliteal cyst-Lower leg	0.002	0.998	0.000
G25.1 Drug-induced tremor	0.002	0.998	0.000
M66.2 Spontaneous rupture of extensor tendons	0.002	0.998	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.002
S09.0 Injury of blood vessels of head, not elsewhere classified	0.002	0.998	0.000
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.002	0.998	0.000
M66.39 Spontaneous rupture of flexor tendons (Site unspecified)	0.002	0.998	0.000
M66.38 Spontaneous rupture of flexor tendons (Other)	0.002	0.998	0.000
M66.37 Spontaneous rupture of flexor tendons (Ankle and foot)	0.002	0.998	0.000
M66.35 Spontaneous rupture of flexor tendons (Pelvic region and thigh)	0.002	0.998	0.000
M66.32 Spontaneous rupture of flexor tendons (Upper arm)	0.002	0.998	0.000
M66.30 Spontaneous rupture of flexor tendons (Multiple sites)	0.002	0.998	0.000
M94.88 Other specified disorders of cartilage (Other)	0.002	0.998	0.000
S27.1 Traumatic haemothorax	0.000	0.998	0.002
Z49.1 Extracorporeal dialysis	0.000	0.998	0.002
Q23 Congenital malformations of aortic and mitral valves	0.000	0.998	0.002
M66.5 Spontaneous rupture of unspecified tendon	0.002	0.998	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.002	0.998	0.000
Q79.5 Other congenital malformations of abdominal wall	0.002	0.998	0.000
Q79.4 Prune belly syndrome	0.002	0.998	0.000
Q79.3 Gastroschisis	0.002	0.998	0.000
Q79.2 Exomphalos	0.002	0.998	0.000
Q79.1 Other congenital malformations of diaphragm	0.002	0.998	0.000
M10.0 Idiopathic gout	0.000	0.998	0.002
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.002	0.998	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.002	0.998	0.000
I62 Other nontraumatic intracranial haemorrhage	0.002	0.998	0.000
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.002	0.998	0.000
D52.8 Other folate deficiency anaemias	0.000	0.998	0.002
D52.1 Drug-induced folate deficiency anaemia	0.000	0.998	0.002
D52.0 Dietary folate deficiency anaemia	0.000	0.998	0.002
G25.2 Other specified forms of tremor	0.002	0.998	0.000
N18.0 End-stage renal disease	0.000	0.998	0.002
M66.4 Spontaneous rupture of other tendons	0.002	0.998	0.000
M10.06 Idiopathic gout (Lower leg)	0.000	0.998	0.002
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.002	0.998	0.000
M86.66 Other chronic osteomyelitis (Lower leg)	0.002	0.998	0.000
C91.1 Chronic lymphocytic leukaemia	0.002	0.998	0.000
K70.3 Alcoholic cirrhosis of liver	0.002	0.998	0.000
G83.2 Monoplegia of upper limb	0.002	0.998	0.000
H47.1 Papilloedema, unspecified	0.002	0.998	0.000
M66.1 Rupture of synovium	0.002	0.998	0.000
K42 Umbilical hernia	0.000	0.998	0.002
E87.5 Hyperkalaemia	0.000	0.998	0.002
Z48.9 Surgical follow-up care, unspecified	0.000	0.998	0.002
W17.6 Industrial and construction area	0.000	0.998	0.002
Q23.0 Congenital stenosis of aortic valve	0.000	0.998	0.002
M24.13 Other articular cartilage disorders (Forearm)	0.002	0.998	0.000
J84 Other interstitial pulmonary diseases	0.000	0.998	0.002
L84 Corns and callosities	0.002	0.998	0.000
M10.19 Lead-induced gout (Site unspecified)	0.000	0.998	0.002
M10.18 Lead-induced gout (Other)	0.000	0.998	0.002
M10.17 Lead-induced gout (Ankle and foot)	0.000	0.998	0.002
M10.16 Lead-induced gout (Lower leg)	0.000	0.998	0.002
M10.15 Lead-induced gout (Pelvic region and thigh)	0.000	0.998	0.002
M10.14 Lead-induced gout (Hand)	0.000	0.998	0.002
M10.13 Lead-induced gout (Forearm)	0.000	0.998	0.002
M10.12 Lead-induced gout (Upper arm)	0.000	0.998	0.002
M10.11 Lead-induced gout (Shoulder region)	0.000	0.998	0.002
M10.10 Lead-induced gout (Multiple sites)	0.000	0.998	0.002
M10.29 Drug-induced gout (Site unspecified)	0.000	0.998	0.002
M10.28 Drug-induced gout (Other)	0.000	0.998	0.002
M10.27 Drug-induced gout (Ankle and foot)	0.000	0.998	0.002
M10.26 Drug-induced gout (Lower leg)	0.000	0.998	0.002
M10.25 Drug-induced gout (Pelvic region and thigh)	0.000	0.998	0.002
M10.24 Drug-induced gout (Hand)	0.000	0.998	0.002
M10.23 Drug-induced gout (Forearm)	0.000	0.998	0.002
M10.22 Drug-induced gout (Upper arm)	0.000	0.998	0.002
M10.21 Drug-induced gout (Shoulder region)	0.000	0.998	0.002
M10.20 Drug-induced gout (Multiple sites)	0.000	0.998	0.002
M10.39 Gout due to impairment of renal function (Site unspecified)	0.000	0.998	0.002
M10.38 Gout due to impairment of renal function (Other)	0.000	0.998	0.002
M10.37 Gout due to impairment of renal function (Ankle and foot)	0.000	0.998	0.002
M10.36 Gout due to impairment of renal function (Lower leg)	0.000	0.998	0.002
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)	0.000	0.998	0.002
M10.34 Gout due to impairment of renal function (Hand)	0.000	0.998	0.002
M10.33 Gout due to impairment of renal function (Forearm)	0.000	0.998	0.002
M10.32 Gout due to impairment of renal function (Upper arm)	0.000	0.998	0.002
M10.31 Gout due to impairment of renal function (Shoulder region)	0.000	0.998	0.002
M10.30 Gout due to impairment of renal function (Multiple sites)	0.000	0.998	0.002
M10.49 Other secondary gout (Site unspecified)	0.000	0.998	0.002
M10.48 Other secondary gout (Other)	0.000	0.998	0.002
M10.47 Other secondary gout (Ankle and foot)	0.000	0.998	0.002
M10.46 Other secondary gout (Lower leg)	0.000	0.998	0.002
M10.45 Other secondary gout (Pelvic region and thigh)	0.000	0.998	0.002
M10.44 Other secondary gout (Hand)	0.000	0.998	0.002
M10.43 Other secondary gout (Forearm)	0.000	0.998	0.002
M10.42 Other secondary gout (Upper arm)	0.000	0.998	0.002
M10.41 Other secondary gout (Shoulder region)	0.000	0.998	0.002
M10.40 Other secondary gout (Multiple sites)	0.000	0.998	0.002
M66.09 Rupture of popliteal cyst-Site unspec	0.002	0.998	0.000
M66.08 Rupture of popliteal cyst-Other	0.002	0.998	0.000
M66.07 Rupture of popliteal cyst-Ankle/foot	0.002	0.998	0.000
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.002	0.998	0.000
M66.04 Rupture of popliteal cyst-Hand	0.002	0.998	0.000
M66.03 Rupture of popliteal cyst-Forearm	0.002	0.998	0.000
M66.02 Rupture of popliteal cyst-Upper arm	0.002	0.998	0.000
M66.01 Rupture of popliteal cyst-Shldr region	0.002	0.998	0.000
M66.00 Rupture of popliteal cyst-Mult sites	0.002	0.998	0.000
M66.57 Spontaneous rupture of unspecified tendon (Ankle and foot)	0.002	0.998	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.002	0.998	0.000
S09.8 Other specified injuries of head	0.001	0.998	0.001
K70 Alcoholic liver disease	0.002	0.998	0.000
H49.1 Fourth [trochlear] nerve palsy	0.002	0.998	0.000
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.002	0.998	0.000
M66.28 Spontaneous rupture of extensor tendons-Other	0.002	0.998	0.000
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.002	0.998	0.000
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.002	0.998	0.000
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.002	0.998	0.000
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.002	0.998	0.000
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.002	0.998	0.000
M66.54 Spontaneous rupture of unspecified tendon (Hand)	0.002	0.998	0.000
G59.0 Diabetic mononeuropathy	0.002	0.998	0.000
K60.2 Anal fissure, unspecified	0.000	0.998	0.002
M65.84 Other synovitis and tenosynovitis (Hand)	0.002	0.998	0.000
D05.0 Lobular carcinoma in situ	0.002	0.998	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.002	0.998	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.000	0.998	0.002
M86.96 Osteomyelitis, unspecified (Lower leg)	0.002	0.998	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.000	0.998	0.002
H65.2 Chronic serous otitis media	0.000	0.998	0.002
M86.6 Other chronic osteomyelitis	0.002	0.998	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.000	0.998	0.002
Q23.8 Other congenital malformations of aortic and mitral valves	0.000	0.998	0.002
Q23.4 Hypoplastic left heart syndrome	0.000	0.998	0.002
Q23.3 Congenital mitral insufficiency	0.000	0.998	0.002
Q23.2 Congenital mitral stenosis	0.000	0.998	0.002
M10.08 Idiopathic gout (Other)	0.000	0.998	0.002
M10.05 Idiopathic gout (Pelvic region and thigh)	0.000	0.998	0.002
M10.04 Idiopathic gout (Hand)	0.000	0.998	0.002
M10.03 Idiopathic gout (Forearm)	0.000	0.998	0.002
M10.02 Idiopathic gout (Upper arm)	0.000	0.998	0.002
M10.01 Idiopathic gout (Shoulder region)	0.000	0.998	0.002
M10.00 Idiopathic gout (Multiple sites)	0.000	0.998	0.002
M66.59 Spontaneous rupture of unspecified tendon (Site unspecified)	0.002	0.998	0.000
M66.58 Spontaneous rupture of unspecified tendon (Other)	0.002	0.998	0.000
M66.56 Spontaneous rupture of unspecified tendon (Lower leg)	0.002	0.998	0.000
M66.55 Spontaneous rupture of unspecified tendon (Pelvic region and thigh)	0.002	0.998	0.000
M66.53 Spontaneous rupture of unspecified tendon (Forearm)	0.002	0.998	0.000
M66.52 Spontaneous rupture of unspecified tendon (Upper arm)	0.002	0.998	0.000
M66.51 Spontaneous rupture of unspecified tendon (Shoulder region)	0.002	0.998	0.000
M66.50 Spontaneous rupture of unspecified tendon (Multiple sites)	0.002	0.998	0.000
O32.1 Maternal care for breech presentation	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.002	0.998	0.000
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.002	0.998	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.001	0.998	0.001
I31.3 Pericardial effusion (noninflammatory)	0.000	0.998	0.002
N17.1 Acute renal failure with acute cortical necrosis	0.000	0.998	0.002
N17 Acute renal failure	0.000	0.998	0.002
M66.49 Spontaneous rupture of other tendons (Site unspecified)	0.002	0.998	0.000
M66.48 Spontaneous rupture of other tendons (Other)	0.002	0.998	0.000
M66.45 Spontaneous rupture of other tendons (Pelvic region and thigh)	0.002	0.998	0.000
M66.44 Spontaneous rupture of other tendons (Hand)	0.002	0.998	0.000
M66.43 Spontaneous rupture of other tendons (Forearm)	0.002	0.998	0.000
M66.42 Spontaneous rupture of other tendons (Upper arm)	0.002	0.998	0.000
M66.40 Spontaneous rupture of other tendons (Multiple sites)	0.002	0.998	0.000
H93.8 Other specified disorders of ear	0.000	0.998	0.002
I62.1 Nontraumatic extradural haemorrhage	0.002	0.998	0.000
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.002	0.998	0.000
M86.69 Other chronic osteomyelitis (Site unspecified)	0.002	0.998	0.000
N17.8 Other acute renal failure	0.000	0.998	0.002
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.998	0.002
R47.8 Other and unspecified speech disturbances	0.002	0.998	0.000
M66.19 Rupture of synovium (Site unspecified)	0.002	0.998	0.000
M66.18 Rupture of synovium (Other)	0.002	0.998	0.000
M66.17 Rupture of synovium (Ankle and foot)	0.002	0.998	0.000
M66.16 Rupture of synovium (Lower leg)	0.002	0.998	0.000
M66.15 Rupture of synovium (Pelvic region and thigh)	0.002	0.998	0.000
M66.14 Rupture of synovium (Hand)	0.002	0.998	0.000
M66.13 Rupture of synovium (Forearm)	0.002	0.998	0.000
M66.12 Rupture of synovium (Upper arm)	0.002	0.998	0.000
M66.11 Rupture of synovium (Shoulder region)	0.002	0.998	0.000
M66.10 Rupture of synovium (Multiple sites)	0.002	0.998	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.998	0.002
G25.3 Myoclonus	0.001	0.998	0.000
K70.1 Alcoholic hepatitis	0.002	0.998	0.000
H93 Other disorders of ear, not elsewhere classified	0.000	0.998	0.002
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.000	0.998	0.002
G25.0 Essential tremor	0.002	0.998	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.002	0.998	0.000
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
J84.0 Alveolar and parietoalveolar conditions	0.000	0.998	0.002
S09.9 Unspecified injury of head	0.002	0.998	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.998	0.002
M62.89 Other specified disorders of muscle (Site unspecified)	0.002	0.998	0.000
M86.47 Chronic osteomyelitis with draining sinus (Ankle and foot)	0.002	0.998	0.000
M86.46 Chronic osteomyelitis with draining sinus (Lower leg)	0.002	0.998	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.002	0.998	0.000
Z99.2 Dependence on renal dialysis	0.000	0.998	0.002
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
M10.09 Idiopathic gout (Site unspecified)	0.000	0.998	0.001
M90.7 Fracture of bone in neoplastic disease	0.000	0.998	0.002
M84.06 Malunion of fracture (Lower leg)	0.002	0.998	0.000
F06.7 Mild cognitive disorder	0.002	0.998	0.000
M22.8 Other disorders of patella	0.000	0.998	0.002
W44.0 Home	0.000	0.998	0.002
M62.84 Other specified disorders of muscle (Hand)	0.002	0.998	0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)	0.002	0.998	0.000
M86.68 Other chronic osteomyelitis (Other)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations