TreeWAS – Variant ID: rs9403856

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R04.0 Epistaxis	0.030	0.970	0.000
O32.1 Maternal care for breech presentation	0.018	0.982	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.016	0.984	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.016	0.984	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.014	0.986	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.014	0.986	0.000
O42.9 Premature rupture of membranes, unspecified	0.014	0.986	0.000
O32.8 Maternal care for other malpresentation of foetus	0.013	0.987	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.013	0.987	0.000
O42 Premature rupture of membranes	0.013	0.987	0.000
O32.0 Maternal care for unstable lie	0.013	0.987	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.013	0.987	0.000
O34.4 Maternal care for other abnormalities of cervix	0.012	0.988	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.012	0.988	0.000
O32.4 Maternal care for high head at term	0.012	0.988	0.000
O32.3 Maternal care for face, brow and chin presentation	0.012	0.988	0.000
O32.6 Maternal care for compound presentation	0.012	0.988	0.000
O34.0 Maternal care for congenital malformation of uterus	0.012	0.988	0.000
O34.3 Maternal care for cervical incompetence	0.011	0.989	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.010	0.989	0.000
O34.6 Maternal care for abnormality of vagina	0.010	0.989	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.010	0.989	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.010	0.989	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.010	0.990	0.000
O34.1 Maternal care for tumour of corpus uteri	0.010	0.990	0.000
O33 Maternal care for known or suspected disproportion	0.010	0.990	0.000
O45 Premature separation of placenta [abruptio placentae]	0.010	0.990	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.009	0.990	0.000
O32.2 Maternal care for transverse and oblique lie	0.009	0.991	0.000
O31 Complications specific to multiple gestation	0.009	0.991	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.009	0.991	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.009	0.991	0.000
L82 Seborrhoeic keratosis	0.000	0.991	0.009
O40 Polyhydramnios	0.009	0.991	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.991	0.009
O43 Placental disorders	0.009	0.991	0.000
O46.9 Antepartum haemorrhage, unspecified	0.009	0.991	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.009	0.991	0.000
O44 Placenta praevia	0.009	0.991	0.000
O47 False labour	0.009	0.991	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.008	0.992	0.000
O33.9 Maternal care for disproportion, unspecified	0.008	0.992	0.000
O30 Multiple gestation	0.008	0.992	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.008	0.992	0.000
O46.8 Other antepartum haemorrhage	0.008	0.992	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.008	0.992	0.000
K83.8 Other specified diseases of biliary tract	0.008	0.992	0.000
O45.9 Premature separation of placenta, unspecified	0.007	0.993	0.000
O33.8 Maternal care for disproportion of other origin	0.007	0.993	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.007	0.993	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.007	0.993	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.007	0.993	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.007	0.993	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.007	0.993	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.007	0.993	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.007	0.993	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.007	0.993	0.000
O43.1 Malformation of placenta	0.007	0.993	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.007	0.993	0.000
O45.8 Other premature separation of placenta	0.007	0.993	0.000
O45.0 Premature separation of placenta with coagulation defect	0.007	0.993	0.000
M18 Arthrosis of first carpometacarpal joint	0.007	0.993	0.000
O31.8 Other complications specific to multiple gestation	0.007	0.993	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.007	0.993	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.007	0.993	0.000
O31.0 Papyraceous foetus	0.007	0.993	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.007	0.993	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.007	0.993	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.007	0.993	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.007	0.993	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.007	0.993	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.007	0.993	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.007	0.993	0.000
O43.9 Placental disorder, unspecified	0.007	0.993	0.000
O43.2 Morbidly adherent placenta	0.007	0.993	0.000
O43.0 Placental transfusion syndromes	0.007	0.993	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.007	0.993	0.000
O44.1 Placenta praevia with haemorrhage	0.007	0.993	0.000
R21 Rash and other nonspecific skin eruption	0.007	0.993	0.000
E10.3 With ophthalmic complications	0.000	0.994	0.006
R79.0 Abnormal level of blood mineral	0.006	0.994	0.000
O47.9 False labour, unspecified	0.006	0.994	0.000
O41 Other disorders of amniotic fluid and membranes	0.006	0.994	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.006	0.994	0.000
O85-O92 Complications predominantly related to the puerperium	0.006	0.994	0.000
O30.9 Multiple gestation, unspecified	0.006	0.994	0.000
O30.8 Other multiple gestation	0.006	0.994	0.000
O30.2 Quadruplet pregnancy	0.006	0.994	0.000
O30.1 Triplet pregnancy	0.006	0.994	0.000
O86 Other puerperal infections	0.006	0.994	0.000
O86.0 Infection of obstetric surgical wound	0.006	0.994	0.000
O43.8 Other placental disorders	0.006	0.994	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.994	0.006
E10.2 With renal complications	0.000	0.994	0.006
O44.0 Placenta praevia specified as without haemorrhage	0.005	0.995	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.005	0.995	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.005	0.995	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.005	0.995	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.005	0.995	0.000
R04 Haemorrhage from respiratory passages	0.005	0.995	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O90 Complications of the puerperium, not elsewhere classified	0.005	0.995	0.000
O85 Puerperal sepsis	0.005	0.995	0.000
O47.0 False labour before 37 completed weeks of gestation	0.005	0.995	0.000
I60 Subarachnoid haemorrhage	0.000	0.995	0.005
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.005	0.995	0.000
Y54.3 Benzothiadiazine derivatives	0.005	0.995	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.005	0.995	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.005	0.995	0.000
E10.1 With ketoacidosis	0.000	0.995	0.005
O16 Unspecified maternal hypertension	0.005	0.995	0.000
R80 Isolated proteinuria	0.000	0.995	0.005
E10.9 Without complications	0.000	0.995	0.005
E10.4 With neurological complications	0.000	0.995	0.005
C77.8 Lymph nodes of multiple regions	0.005	0.995	0.000
Z92.3 Personal history of irradiation	0.000	0.995	0.005
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.005	0.995	0.000
R79 Other abnormal findings of blood chemistry	0.005	0.995	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.005	0.995	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.995	0.005
Y44 Agents primarily affecting blood constituents	0.005	0.995	0.000
Y54.8 Agents affecting uric acid metabolism	0.005	0.995	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.005	0.995	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.005	0.995	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.005	0.995	0.000
O86.1 Other infection of genital tract following delivery	0.005	0.995	0.000
O90.2 Haematoma of obstetric wound	0.005	0.995	0.000
O86.4 Pyrexia of unknown origin following delivery	0.005	0.995	0.000
C77.1 Intrathoracic lymph nodes	0.005	0.995	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.004	0.995	0.000
O41.1 Infection of amniotic sac and membranes	0.004	0.995	0.000
O90.1 Disruption of perineal obstetric wound	0.004	0.995	0.000
O91 Infections of breast associated with childbirth	0.004	0.995	0.000
O89 Complications of anaesthesia during the puerperium	0.004	0.995	0.000
O88 Obstetric embolism	0.004	0.995	0.000
B34.9 Viral infection, unspecified	0.005	0.995	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.005	0.995	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.005	0.995	0.000
O86.8 Other specified puerperal infections	0.004	0.995	0.000
O86.3 Other genito-urinary tract infections following delivery	0.004	0.995	0.000
O86.2 Urinary tract infection following delivery	0.004	0.995	0.000
O87 Venous complications in the puerperium	0.004	0.996	0.000
Y52 Agents primarily affecting the cardiovascular system	0.004	0.996	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.004	0.996	0.000
Y59 Other and unspecified vaccines and biological substances	0.004	0.996	0.000
O30.0 Twin pregnancy	0.004	0.996	0.000
R79.8 Other specified abnormal findings of blood chemistry	0.004	0.996	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
E10.7 With multiple complications	0.000	0.996	0.004
Y44.2 Anticoagulants	0.004	0.996	0.000
Y42.7 Androgens and anabolic congeners	0.004	0.996	0.000
Y54.7 Agents affecting calcification	0.004	0.996	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.996	0.004
R04.9 Haemorrhage from respiratory passages, unspecified	0.004	0.996	0.000
R04.1 Haemorrhage from throat	0.004	0.996	0.000
R04.8 Haemorrhage from other sites in respiratory passages	0.004	0.996	0.000
Y44.5 Thrombolytic drugs	0.004	0.996	0.000
J98.1 Pulmonary collapse	0.004	0.996	0.000
Y59.3 Immunoglobulin	0.004	0.996	0.000
E10.6 With other specified complications	0.000	0.996	0.004
I60.8 Other subarachnoid haemorrhage	0.000	0.996	0.004
O90.5 Postpartum thyroiditis	0.004	0.996	0.000
O90.4 Postpartum acute renal failure	0.004	0.996	0.000
O90.3 Cardiomyopathy in the puerperium	0.004	0.996	0.000
O90.0 Disruption of Caesarean section wound	0.004	0.996	0.000
S52.6 Fracture of lower end of both ulna and radius	0.004	0.996	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.996	0.004
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.996	0.004
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.996	0.004
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.996	0.004
Y42.0 Glucocorticoids and synthetic analogs	0.004	0.996	0.000
Y54.4 Loop [high-ceiling] diuretics	0.004	0.996	0.000
J03.9 Acute tonsillitis, unspecified	0.004	0.996	0.000
O70.0 First degree perineal laceration during delivery	0.004	0.996	0.000
Y54.9 Mineral salts, not elsewhere classified	0.004	0.996	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.004	0.996	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.004	0.996	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.004	0.996	0.000
Y54.0 Mineralocorticoids	0.004	0.996	0.000
E10.8 With unspecified complications	0.000	0.996	0.004
O90.9 Complication of the puerperium, unspecified	0.004	0.996	0.000
S52.30 Fracture of shaft of radius (closed)	0.004	0.996	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.004	0.996	0.000
S52 Fracture of forearm	0.004	0.996	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.004	0.996	0.000
S52.3 Fracture of shaft of radius	0.004	0.996	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.004	0.996	0.000
E10.0 With coma	0.000	0.996	0.004
O82.0 Delivery by elective Caesarean section	0.004	0.996	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.004	0.996	0.000
Y42.5 Other oestrogens and progestogens	0.004	0.996	0.000
Y43 Primarily systemic agents	0.004	0.996	0.000
Y48 Anaesthetics and therapeutic gases	0.004	0.996	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.003	0.996	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.004	0.996	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.004	0.996	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
O87.8 Other venous complications in the puerperium	0.004	0.996	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
Y58 Bacterial vaccines	0.004	0.996	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.004	0.996	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.004	0.996	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.004	0.996	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.996	0.004
Y42.9 Other and unspecified hormone antagonists	0.004	0.996	0.000
Y42.4 Oral contraceptives	0.004	0.996	0.000
Y42.2 Antithyroid drugs	0.004	0.996	0.000
Y42.1 Thyroid hormones and substitutes	0.004	0.996	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.004	0.996	0.000
Y44.7 Plasma substitutes	0.004	0.996	0.000
Y44.6 Natural blood and blood products	0.004	0.996	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.004	0.996	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.004	0.996	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.004	0.996	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.004	0.996	0.000
O82 Single delivery by Caesarean section	0.004	0.996	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.004	0.996	0.000
O80-O84 Delivery	0.004	0.996	0.000
O15 Eclampsia	0.003	0.996	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.003	0.996	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.004	0.996	0.000
O70 Perineal laceration during delivery	0.004	0.996	0.000
C15.4 Middle third of oesophagus	0.004	0.996	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.996	0.003
S52.1 Fracture of upper end of radius	0.004	0.996	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.004	0.996	0.000
K08.3 Retained dental root	0.004	0.996	0.000
O70.2 Third degree perineal laceration during delivery	0.004	0.996	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.004	0.996	0.000
O88.8 Other obstetric embolism	0.003	0.996	0.000
O88.3 Obstetric pyaemic and septic embolism	0.003	0.996	0.000
O88.2 Obstetric blood-clot embolism	0.003	0.996	0.000
O88.1 Amniotic fluid embolism	0.003	0.996	0.000
O88.0 Obstetric air embolism	0.003	0.996	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.003	0.996	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.003	0.996	0.000
O89.6 Failed or difficult intubation during the puerperium	0.003	0.996	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.003	0.996	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.003	0.996	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.003	0.996	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.003	0.996	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.003	0.996	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.003	0.996	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.003	0.996	0.000
O91.1 Abscess of breast associated with childbirth	0.003	0.996	0.000
O91.0 Infection of nipple associated with childbirth	0.003	0.996	0.000
R56.8 Other and unspecified convulsions	0.000	0.996	0.004
E10.5 With peripheral circulatory complications	0.000	0.996	0.003
O87.9 Venous complication in the puerperium, unspecified	0.003	0.997	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.003	0.997	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.003	0.997	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.003	0.997	0.000
Y43.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.003	0.997	0.000
Y52.7 Peripheral vasodilators	0.003	0.997	0.000
S52.10 Fracture of upper end of radius (closed)	0.003	0.997	0.000
O92.7 Other and unspecified disorders of lactation	0.003	0.997	0.000
O92.6 Galactorrhoea	0.003	0.997	0.000
O92.5 Suppressed lactation	0.003	0.997	0.000
O92.4 Hypogalactia	0.003	0.997	0.000
O92.3 Agalactia	0.003	0.997	0.000
O92.1 Cracked nipple associated with childbirth	0.003	0.997	0.000
O92.0 Retracted nipple associated with childbirth	0.003	0.997	0.000
S52.0 Fracture of upper end of ulna	0.003	0.997	0.000
Y59.9 Vaccine or biological substance, unspecified	0.003	0.997	0.000
Y59.8 Other specified vaccines and biological substances	0.003	0.997	0.000
Y59.2 Protozoal vaccines	0.003	0.997	0.000
Y59.1 Rickettsial vaccines	0.003	0.997	0.000
Y59.0 Viral vaccines	0.003	0.997	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.003	0.997	0.000
Y43.1 Antineoplastic antimetabolites	0.003	0.997	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
Y48.4 Anaesthetic, unspecified	0.003	0.997	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.003	0.997	0.000
Y54.5 Other diuretics	0.003	0.997	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.003	0.997	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.000	0.997	0.003
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
Z49.1 Extracorporeal dialysis	0.003	0.997	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
Y46.2 Hydantoin derivatives	0.003	0.997	0.000
R81 Glycosuria	0.000	0.997	0.003
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.003	0.997	0.000
Y41.1 Antimycobacterial drugs	0.003	0.997	0.000
O62 Abnormalities of forces of labour	0.003	0.997	0.000
O82.1 Delivery by emergency Caesarean section	0.003	0.997	0.000
S43.0 Dislocation of shoulder joint	0.003	0.997	0.000
Y52.1 Calcium-channel blockers	0.003	0.997	0.000
O62.1 Secondary uterine inertia	0.003	0.997	0.000
S52.9 Fracture of forearm, part unspecified	0.003	0.997	0.000
S52.4 Fracture of shafts of both ulna and radius	0.003	0.997	0.000
O12.2 Gestational oedema with proteinuria	0.003	0.997	0.000
O87.2 Haemorrhoids in the puerperium	0.003	0.997	0.000
S52.2 Fracture of shaft of ulna	0.003	0.997	0.000
Y46.8 Antispasticity drugs	0.003	0.997	0.000
Y46.7 Anti-Parkinsonism drugs	0.003	0.997	0.000
Y46.6 Other and unspecified antiepileptics	0.003	0.997	0.000
Y46.5 Valproic acid	0.003	0.997	0.000
Y46.4 Iminostilbenes	0.003	0.997	0.000
Y46.3 Deoxybarbiturates	0.003	0.997	0.000
Y46.1 Oxazolidinediones	0.003	0.997	0.000
Y46.0 Succinimides	0.003	0.997	0.000
C53.9 Cervix uteri, unspecified	0.000	0.997	0.003
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.003	0.997	0.000
S52.31 Fracture of shaft of radius (open)	0.003	0.997	0.000
Y49.5 Other antipsychotics and neuroleptics	0.003	0.997	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O97 Death from sequelae of direct obstetric causes	0.003	0.997	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.003	0.997	0.000
O95 Obstetric death of unspecified cause	0.003	0.997	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.003	0.997	0.000
Y57 Other and unspecified drugs and medicaments	0.003	0.997	0.000
O60-O75 Complications of labour and delivery	0.003	0.997	0.000
O14.0 Moderate preeclampsia	0.003	0.997	0.000
Y53.4 Other laxatives	0.003	0.997	0.000
S52.00 Fracture of upper end of ulna (closed)	0.003	0.997	0.000
Y43.9 Primarily systemic agent, unspecified	0.003	0.997	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.003	0.997	0.000
Y43.6 Enzymes, not elsewhere classified	0.003	0.997	0.000
Y43.5 Acidifying and alkalising agents	0.003	0.997	0.000
Y43.2 Antineoplastic natural products	0.003	0.997	0.000
Y48.5 Therapeutic gases	0.003	0.997	0.000
Y48.1 Parenteral anaesthetics	0.003	0.997	0.000
Y48.0 Inhaled anaesthetics	0.003	0.997	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.003	0.997	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
Y53.7 Emetics	0.003	0.997	0.000
Y53.6 Antidiarrhoeal drugs	0.003	0.997	0.000
Y53.5 Digestants	0.003	0.997	0.000
Y53.3 Saline and osmotic laxatives	0.003	0.997	0.000
Y53.2 Stimulant laxatives	0.003	0.997	0.000
Y53.0 Histamine H2-receptor antagonists	0.003	0.997	0.000
O41.0 Oligohydramnios	0.002	0.997	0.001
S52.7 Multiple fractures of forearm	0.003	0.997	0.000
Y49.9 Psychotropic drug, unspecified	0.003	0.997	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
Y49.7 Psychostimulants with abuse potential	0.003	0.997	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.003	0.997	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.003	0.997	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.003	0.997	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.003	0.997	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
Y56.9 Topical agent, unspecified	0.003	0.997	0.000
Y56.8 Other topical agents	0.003	0.997	0.000
Y56.7 Dental drugs, topically applied	0.003	0.997	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.003	0.997	0.000
Y56.5 Ophthalmological drugs and preparations	0.003	0.997	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.997	0.000
Y56.3 Emollients, demulcents and protectants	0.003	0.997	0.000
Y56.2 Local astringents and local detergents	0.003	0.997	0.000
Y56.1 Antipruritics	0.003	0.997	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.997	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.003	0.997	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.003	0.997	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.003	0.997	0.000
Y47.4 Bromine compounds	0.003	0.997	0.000
Y47.3 Paraldehyde	0.003	0.997	0.000
Y47.2 Chloral derivatives	0.003	0.997	0.000
Y47.1 Benzodiazepines	0.003	0.997	0.000
Y47.0 Barbiturates, not elsewhere classified	0.003	0.997	0.000
Y50.9 Central nervous system stimulant, unspecified	0.003	0.997	0.000
Y50.8 Other central nervous system stimulants	0.003	0.997	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.003	0.997	0.000
Y50.1 Opioid receptor antagonists	0.003	0.997	0.000
Y50.0 Analeptics	0.003	0.997	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.997	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.003	0.997	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.997	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.003	0.997	0.000
Y51.0 Anticholinesterase agents	0.003	0.997	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.003	0.997	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.003	0.997	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.003	0.997	0.000
Y55.5 Anticommon cold drugs	0.003	0.997	0.000
Y55.4 Expectorants	0.003	0.997	0.000
Y55.3 Antitussives	0.003	0.997	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.003	0.997	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.003	0.997	0.000
Y55.0 Oxytocic drugs	0.003	0.997	0.000
Y58.9 Other and unspecified bacterial vaccines	0.003	0.997	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.003	0.997	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.003	0.997	0.000
Y58.5 Diphtheria vaccine	0.003	0.997	0.000
Y58.4 Tetanus vaccine	0.003	0.997	0.000
Y58.3 Plague vaccine	0.003	0.997	0.000
Y58.2 Cholera vaccine	0.003	0.997	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.003	0.997	0.000
Y58.0 BCG vaccine	0.003	0.997	0.000
R73.9 Hyperglycaemia, unspecified	0.003	0.997	0.000
O82.8 Other single delivery by Caesarean section	0.003	0.997	0.000
O82.2 Delivery by Caesarean hysterectomy	0.003	0.997	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
Y41.5 Antiviral drugs	0.003	0.997	0.000
Y41.4 Anthelminthics	0.003	0.997	0.000
Y41.3 Other antiprotozoal drugs	0.003	0.997	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
O84 Multiple delivery	0.003	0.997	0.000
O83 Other assisted single delivery	0.003	0.997	0.000
O15.9 Eclampsia, unspecified as to time period	0.003	0.997	0.000
O15.2 Eclampsia in the puerperium	0.003	0.997	0.000
O15.1 Eclampsia in labour	0.003	0.997	0.000
O15.0 Eclampsia in pregnancy	0.003	0.997	0.000
Y49.2 Other and unspecified antidepressants	0.003	0.997	0.000
K08 Other disorders of teeth and supporting structures	0.003	0.997	0.000
O48 Prolonged pregnancy	0.003	0.997	0.000
O70.3 Fourth degree perineal laceration during delivery	0.003	0.997	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.003	0.997	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.000	0.997	0.003
S52.11 Fracture of upper end of radius (open)	0.003	0.997	0.000
S52.5 Fracture of lower end of radius	0.003	0.997	0.000
Y48.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
O14.2 HELLP syndrome	0.003	0.997	0.000
O12.1 Gestational proteinuria	0.003	0.997	0.000
S52.8 Fracture of other parts of forearm	0.003	0.997	0.000
Y41.0 Sulphonamides	0.003	0.997	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.003	0.997	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.000	0.997	0.003
K08.9 Disorder of teeth and supporting structures, unspecified	0.003	0.997	0.000
S52.01 Fracture of upper end of ulna (open)	0.003	0.997	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.003	0.997	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.000	0.997	0.003
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.003	0.997	0.000
Y45.5 4-Aminophenol derivatives	0.003	0.997	0.000
Y48.3 Local anaesthetics	0.003	0.997	0.000
O62.3 Precipitate labour	0.003	0.997	0.000
O70.9 Perineal laceration during delivery, unspecified	0.003	0.997	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.000	0.997	0.003
O20-O29 Other maternal disorders predominantly related to pregnancy	0.003	0.997	0.000
O14.9 Preeclampsia, unspecified	0.003	0.997	0.000
N62 Hypertrophy of breast	0.003	0.997	0.000
R82 Other abnormal findings in urine	0.000	0.997	0.003
B34 Viral infection of unspecified site	0.003	0.997	0.000
O73 Retained placenta and membranes, without haemorrhage	0.003	0.997	0.000
O81 Single delivery by forceps and vacuum extractor	0.003	0.997	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
Y43.4 Immunosuppressive agents	0.003	0.997	0.000
O82.9 Delivery by Caesarean section, unspecified	0.002	0.997	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.997	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.003	0.997	0.000
O62.2 Other uterine inertia	0.003	0.997	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.003	0.997	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.997	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.997	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.002	0.997	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.002	0.997	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.002	0.997	0.000
O14.1 Severe preeclampsia	0.002	0.997	0.000
Y45.1 Salicylates	0.003	0.997	0.000
O22 Venous complications in pregnancy	0.002	0.997	0.000
O12.0 Gestational oedema	0.002	0.997	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.000	0.997	0.003
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
R74.8 Abnormal levels of other serum enzymes	0.002	0.997	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.997	0.000
R74 Abnormal serum enzyme levels	0.002	0.997	0.000
O62.9 Abnormality of forces of labour, unspecified	0.002	0.997	0.000
O62.8 Other abnormalities of forces of labour	0.002	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.997	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.002	0.997	0.000
Q79.6 Ehlers-Danlos syndrome	0.002	0.997	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.003	0.997	0.000
C15.3 Upper third of oesophagus	0.002	0.997	0.000
S52.41 Fracture of shafts of both ulna and radius (open)	0.002	0.998	0.000
S52.40 Fracture of shafts of both ulna and radius (closed)	0.002	0.998	0.000
S52.91 Fracture of forearm, part unspecified (open)	0.002	0.998	0.000
S52.90 Fracture of forearm, part unspecified (closed)	0.002	0.998	0.000
L60.8 Other nail disorders	0.000	0.998	0.002
S52.21 Fracture of shaft of ulna (open)	0.002	0.998	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.002	0.998	0.000
Y45.4 Antirheumatics	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
O96.9 Death from unspecified obstetric cause	0.002	0.998	0.000
O96.1 Death from indirect obstetric cause	0.002	0.998	0.000
O96.0 Death from direct obstetric cause	0.002	0.998	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.002	0.998	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.002	0.998	0.000
O97.0 Death from sequelae of direct obstetric cause	0.002	0.998	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.6 Other diagnostic agents	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations