TreeWAS – Variant ID: rs9467703

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.996	0.004	0.000
K90 Intestinal malabsorption	0.000	0.623	0.377
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.696	0.304
E83 Disorders of mineral metabolism	0.293	0.707	0.000
K90.8 Other intestinal malabsorption	0.000	0.726	0.273
K90.3 Pancreatic steatorrhoea	0.000	0.729	0.271
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.729	0.271
K90.1 Tropical sprue	0.000	0.729	0.271
I83 Varicose veins of lower extremities	0.262	0.738	0.000
E83.3 Disorders of phosphorus metabolism	0.261	0.739	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.233	0.767	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.232	0.767	0.000
E83.8 Other disorders of mineral metabolism	0.210	0.790	0.000
E83.2 Disorders of zinc metabolism	0.210	0.790	0.000
E83.0 Disorders of copper metabolism	0.210	0.790	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.822	0.177
C64 Malignant neoplasm of kidney, except renal pelvis	0.126	0.874	0.000
E83.4 Disorders of magnesium metabolism	0.114	0.886	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.102	0.897	0.001
T39.1 4-Aminophenol derivatives	0.096	0.904	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.093	0.907	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.092	0.908	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.091	0.909	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.091	0.909	0.000
T43.2 Other and unspecified antidepressants	0.087	0.913	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.084	0.916	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.081	0.919	0.000
R79.0 Abnormal level of blood mineral	0.081	0.919	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.081	0.919	0.000
T36 Poisoning by systemic antibiotics	0.079	0.921	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.078	0.922	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.076	0.924	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.075	0.925	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.074	0.926	0.000
T43.9 Psychotropic drug, unspecified	0.074	0.926	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.072	0.927	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.071	0.929	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.069	0.931	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.067	0.933	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.067	0.933	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.067	0.933	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.067	0.933	0.000
T42.0 Hydantoin derivatives	0.066	0.934	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.066	0.934	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.065	0.935	0.000
T39.4 Antirheumatics, not elsewhere classified	0.065	0.935	0.000
T39.2 Pyrazolone derivatives	0.065	0.935	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.065	0.935	0.000
T36.3 Macrolides	0.065	0.935	0.000
T36.8 Other systemic antibiotics	0.064	0.936	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.063	0.937	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.062	0.938	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.061	0.939	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.061	0.939	0.000
T48.5 Anti-common-cold drugs	0.061	0.939	0.000
T47.0 Histamine H(2)-receptor antagonists	0.060	0.940	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.060	0.940	0.000
T40.2 Other opioids	0.060	0.940	0.000
D64.9 Anaemia, unspecified	0.000	0.941	0.059
T38.1 Thyroid hormones and substitutes	0.059	0.941	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.059	0.941	0.000
T42.3 Barbiturates	0.059	0.941	0.000
T42.2 Succinimides and oxazolidinediones	0.059	0.941	0.000
G95.8 Other specified diseases of spinal cord	0.058	0.942	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.058	0.942	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.058	0.942	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.058	0.942	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.058	0.942	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.058	0.942	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.058	0.942	0.000
T44.0 Anticholinesterase agents	0.058	0.942	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.058	0.942	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.057	0.942	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.057	0.943	0.000
T36.9 Systemic antibiotic, unspecified	0.057	0.943	0.000
T36.7 Antifungal antibiotics, systemically used	0.057	0.943	0.000
T36.6 Rifamycins	0.057	0.943	0.000
T36.5 Aminoglycosides	0.057	0.943	0.000
T36.2 Chloramphenicol group	0.057	0.943	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.057	0.943	0.000
T36.4 Tetracyclines	0.056	0.943	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.056	0.943	0.000
T38.9 Other and unspecified hormone antagonists	0.056	0.944	0.000
T38.7 Androgens and anabolic congeners	0.056	0.944	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.056	0.944	0.000
T38.5 Other oestrogens and progestogens	0.056	0.944	0.000
T38.4 Oral contraceptives	0.056	0.944	0.000
T38.2 Antithyroid drugs	0.056	0.944	0.000
T38.0 Glucocorticoids and synthetic analogues	0.056	0.944	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.056	0.944	0.000
T47.6 Antidiarrhoeal drugs	0.055	0.945	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.055	0.945	0.000
T42.4 Benzodiazepines	0.054	0.946	0.000
T36.0 Penicillins	0.054	0.946	0.000
T47.4 Other laxatives	0.054	0.946	0.000
G25 Other extrapyramidal and movement disorders	0.054	0.946	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.054	0.946	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.054	0.946	0.000
T47.7 Emetics	0.054	0.946	0.000
T47.5 Digestants	0.054	0.946	0.000
T47.3 Saline and osmotic laxatives	0.054	0.946	0.000
T47.2 Stimulant laxatives	0.054	0.946	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.053	0.946	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.053	0.946	0.000
T48.4 Expectorants	0.053	0.946	0.000
T48.3 Antitussives	0.053	0.946	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.053	0.946	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.053	0.946	0.000
T48.0 Oxytocic drugs	0.053	0.946	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.053	0.946	0.000
G95 Other diseases of spinal cord	0.053	0.947	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.053	0.947	0.000
T42.1 Iminostilbenes	0.052	0.947	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.052	0.948	0.000
T37.5 Antiviral drugs	0.052	0.948	0.000
T37.4 Anthelminthics	0.052	0.948	0.000
T37.3 Other antiprotozoal drugs	0.052	0.948	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.052	0.948	0.000
T37.1 Antimycobacterial drugs	0.052	0.948	0.000
T37.0 Sulphonamides	0.052	0.948	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.051	0.949	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.051	0.949	0.000
T40.8 Lysergide [LSD]	0.051	0.949	0.000
T40.7 Cannabis (derivatives)	0.051	0.949	0.000
T40.3 Methadone	0.051	0.949	0.000
T40.0 Opium	0.051	0.949	0.000
G25.3 Myoclonus	0.051	0.949	0.000
G95.2 Cord compression, unspecified	0.051	0.949	0.000
T40.1 Heroin	0.051	0.949	0.000
T40.5 Cocaine	0.050	0.950	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.049	0.951	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.049	0.951	0.000
T49.9 Topical agent, unspecified	0.048	0.951	0.000
T49.8 Other topical agents	0.048	0.951	0.000
T49.7 Dental drugs, topically applied	0.048	0.951	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.048	0.951	0.000
T49.5 Ophthalmological drugs and preparations	0.048	0.951	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.048	0.951	0.000
T49.3 Emollients, demulcents and protectants	0.048	0.951	0.000
T49.2 Local astringents and local detergents	0.048	0.951	0.000
T49.1 Antipruritics	0.048	0.951	0.000
T41.5 Therapeutic gases	0.048	0.952	0.000
T41.4 Anaesthetic, unspecified	0.048	0.952	0.000
T41.3 Local anaesthetics	0.048	0.952	0.000
T41.2 Other and unspecified general anaesthetics	0.048	0.952	0.000
T41.1 Intravenous anaesthetics	0.048	0.952	0.000
T41.0 Inhaled anaesthetics	0.048	0.952	0.000
T40.4 Other synthetic narcotics	0.048	0.952	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.048	0.952	0.000
T40.6 Other and unspecified narcotics	0.048	0.952	0.000
G20-G26 Extrapyramidal and movement disorders	0.047	0.953	0.000
T43.6 Psychostimulants with abuse potential	0.046	0.953	0.000
R40.0 Somnolence	0.000	0.954	0.046
G59.0 Diabetic mononeuropathy	0.046	0.954	0.000
G90-G99 Other disorders of the nervous system	0.046	0.954	0.000
T39.0 Salicylates	0.046	0.954	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.045	0.955	0.000
G25.1 Drug-induced tremor	0.044	0.956	0.000
G25.0 Essential tremor	0.044	0.956	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.043	0.956	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.043	0.956	0.000
T46.7 Peripheral vasodilators	0.043	0.956	0.000
T50.8 Diagnostic agents	0.043	0.957	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.043	0.957	0.000
T45.5 Anticoagulants	0.042	0.957	0.000
T45.0 Antiallergic and antiemetic drugs	0.042	0.958	0.000
Chapter VI Diseases of the nervous system	0.042	0.958	0.000
N39.3 Stress incontinence	0.042	0.958	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.042	0.958	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.041	0.959	0.000
T50.7 Analeptics and opioid receptor antagonists	0.041	0.959	0.000
T50.5 Appetite depressants	0.041	0.959	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.041	0.959	0.000
T50.1 Loop [high-ceiling] diuretics	0.041	0.959	0.000
T50.0 Mineralocorticoids and their antagonists	0.041	0.959	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.040	0.959	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.040	0.960	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.040	0.960	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.040	0.960	0.000
T45.8 Other primarily systemic and haematological agents	0.040	0.960	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.040	0.960	0.000
T45.6 Fibrinolysis-affecting drugs	0.040	0.960	0.000
T45.4 Iron and its compounds	0.040	0.960	0.000
T45.3 Enzymes, not elsewhere classified	0.040	0.960	0.000
T50.4 Drugs affecting uric acid metabolism	0.040	0.960	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.039	0.961	0.000
G25.4 Drug-induced chorea	0.039	0.961	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.039	0.961	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.039	0.961	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.038	0.961	0.000
G95.0 Syringomyelia and syringobulbia	0.038	0.962	0.000
T45.2 Vitamins, not elsewhere classified	0.038	0.962	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.037	0.963	0.000
Z46.6 Fitting and adjustment of urinary device	0.037	0.963	0.000
G95.9 Disease of spinal cord, unspecified	0.037	0.963	0.000
G24 Dystonia	0.036	0.963	0.000
G23 Other degenerative diseases of basal ganglia	0.036	0.964	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.035	0.965	0.000
T46.1 Calcium-channel blockers	0.035	0.965	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.035	0.965	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.035	0.965	0.000
G91 Hydrocephalus	0.035	0.965	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.035	0.965	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.034	0.966	0.000
G22 Parkinsonism in diseases classified elsewhere	0.034	0.966	0.000
G25.2 Other specified forms of tremor	0.034	0.966	0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.033	0.967	0.000
G25.5 Other chorea	0.033	0.967	0.000
G21 Secondary Parkinsonism	0.033	0.967	0.000
G92 Toxic encephalopathy	0.033	0.967	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.033	0.967	0.000
C64-C68 Malignant neoplasms of urinary tract	0.033	0.967	0.000
G96 Other disorders of central nervous system	0.033	0.967	0.000
G20 Parkinson's disease	0.033	0.967	0.000
G54 Nerve root and plexus disorders	0.032	0.968	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.032	0.968	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.032	0.968	0.000
G52 Disorders of other cranial nerves	0.031	0.969	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.031	0.969	0.000
G54.0 Brachial plexus disorders	0.031	0.969	0.000
R79 Other abnormal findings of blood chemistry	0.031	0.969	0.000
T51.0 Ethanol	0.031	0.969	0.000
G59.8 Other mononeuropathies in diseases classified elsewhere	0.031	0.969	0.000
G60 Hereditary and idiopathic neuropathy	0.031	0.969	0.000
N39 Other disorders of urinary system	0.031	0.969	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.030	0.970	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.030	0.970	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.030	0.970	0.000
G91.8 Other hydrocephalus	0.030	0.970	0.000
E83.5 Disorders of calcium metabolism	0.030	0.970	0.000
N39.8 Other specified disorders of urinary system	0.030	0.970	0.000
G24.3 Spasmodic torticollis	0.029	0.970	0.000
G24.5 Blepharospasm	0.029	0.971	0.000
G24.0 Drug-induced dystonia	0.029	0.971	0.000
C65 Malignant neoplasm of renal pelvis	0.029	0.971	0.000
G58 Other mononeuropathies	0.029	0.971	0.000
G90 Disorders of autonomic nervous system	0.029	0.971	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.029	0.971	0.000
G60.8 Other hereditary and idiopathic neuropathies	0.028	0.972	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.028	0.972	0.000
N39.0 Urinary tract infection, site not specified	0.028	0.972	0.000
G94.1 Hydrocephalus in neoplastic disease	0.027	0.973	0.000
G30-G32 Other degenerative diseases of the nervous system	0.027	0.973	0.000
G91.0 Communicating hydrocephalus	0.027	0.973	0.000
D64 Other anaemias	0.000	0.973	0.027
G91.9 Hydrocephalus, unspecified	0.026	0.974	0.000
G24.4 Idiopathic orofacial dystonia	0.026	0.974	0.000
G24.2 Idiopathic nonfamilial dystonia	0.026	0.974	0.000
G24.1 Idiopathic familial dystonia	0.026	0.974	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.026	0.974	0.000
G58.8 Other specified mononeuropathies	0.026	0.974	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.026	0.974	0.000
G23.3 Multiple system atrophy, cerebellar type	0.026	0.974	0.000
G23.2 Striatonigral degeneration	0.026	0.974	0.000
G23.0 Hallervorden-Spatz disease	0.026	0.974	0.000
G37 Other demyelinating diseases of central nervous system	0.026	0.974	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.025	0.974	0.000
G51 Facial nerve disorders	0.026	0.974	0.000
G52.7 Disorders of multiple cranial nerves	0.025	0.974	0.000
G54.8 Other nerve root and plexus disorders	0.025	0.974	0.000
G54.5 Neuralgic amyotrophy	0.025	0.974	0.000
G60.0 Hereditary motor and sensory neuropathy	0.025	0.975	0.000
G21.9 Secondary Parkinsonism, unspecified	0.025	0.975	0.000
E70-E90 Metabolic disorders	0.025	0.975	0.000
G52.3 Disorders of hypoglossal nerve	0.025	0.975	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.025	0.975	0.000
G50 Disorders of trigeminal nerve	0.025	0.975	0.000
G24.8 Other dystonia	0.024	0.975	0.000
G96.8 Other specified disorders of central nervous system	0.024	0.976	0.000
G64 Other disorders of peripheral nervous system	0.024	0.976	0.000
G70-G73 Diseases of myoneural junction and muscle	0.024	0.976	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.024	0.976	0.000
G21.8 Other secondary Parkinsonism	0.024	0.976	0.000
G21.4 Vascular parkinsonism	0.024	0.976	0.000
G21.3 Postencephalitic Parkinsonism	0.024	0.976	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.024	0.976	0.000
G21.0 Malignant neuroleptic syndrome	0.024	0.976	0.000
G51.3 Clonic hemifacial spasm	0.024	0.976	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.024	0.976	0.001
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.024	0.976	0.000
G91.2 Normal-pressure hydrocephalus	0.024	0.976	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.024	0.976	0.000
G96.9 Disorder of central nervous system, unspecified	0.023	0.976	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.023	0.976	0.000
G61 Inflammatory polyneuropathy	0.023	0.976	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.023	0.977	0.000
G54.7 Phantom limb syndrome without pain	0.023	0.977	0.000
G54.3 Thoracic root disorders, not elsewhere classified	0.023	0.977	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.023	0.977	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.023	0.977	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.023	0.977	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.023	0.977	0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.023	0.977	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.023	0.977	0.000
K90-K93 Other diseases of the digestive system	0.000	0.977	0.023
G96.1 Disorders of meninges, not elsewhere classified	0.023	0.977	0.000
G52.1 Disorders of glossopharyngeal nerve	0.023	0.977	0.000
G52.2 Disorders of vagus nerve	0.023	0.977	0.000
G52.0 Disorders of olfactory nerve	0.023	0.977	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.023	0.977	0.000
G96.0 Cerebrospinal fluid leak	0.023	0.977	0.000
G52.8 Disorders of other specified cranial nerves	0.022	0.977	0.000
F17.1 Harmful use	0.023	0.977	0.000
E88 Other metabolic disorders	0.022	0.977	0.000
G11 Hereditary ataxia	0.022	0.978	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.022	0.978	0.000
G60.3 Idiopathic progressive neuropathy	0.022	0.978	0.000
G60.2 Neuropathy in association with hereditary ataxia	0.022	0.978	0.000
G60.1 Refsum's disease	0.022	0.978	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.022	0.978	0.000
G54.2 Cervical root disorders, not elsewhere classified	0.022	0.978	0.000
N39.2 Orthostatic proteinuria, unspecified	0.022	0.978	0.000
G82 Paraplegia and tetraplegia	0.022	0.978	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.022	0.978	0.000
G54.1 Lumbosacral plexus disorders	0.022	0.978	0.000
G36 Other acute disseminated demyelination	0.022	0.978	0.000
G40-G47 Episodic and paroxysmal disorders	0.022	0.978	0.000
G95.1 Vascular myelopathies	0.021	0.978	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.022	0.978	0.000
G40 Epilepsy	0.022	0.978	0.000
G82.2 Paraplegia, unspecified	0.022	0.978	0.000
E85 Amyloidosis	0.021	0.979	0.000
G61.8 Other inflammatory polyneuropathies	0.021	0.979	0.000
Z72.0 Tobacco use	0.021	0.979	0.000
G90.4 Autonomic dysreflexia	0.021	0.979	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.021	0.979	0.000
G10 Huntington's disease	0.021	0.979	0.000
G14 Postpolio syndrome	0.021	0.979	0.000
R79.8 Other specified abnormal findings of blood chemistry	0.021	0.979	0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.020	0.979	0.000
G93 Other disorders of brain	0.021	0.979	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.020	0.979	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.020	0.980	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.020	0.980	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.020	0.980	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.020	0.980	0.000
G72 Other myopathies	0.020	0.980	0.000
G30 Alzheimer's disease	0.019	0.981	0.000
D64.4 Congenital dyserythropoietic anaemia	0.000	0.981	0.019
D64.3 Other sideroblastic anaemias	0.000	0.981	0.019
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.000	0.981	0.019
D64.1 Secondary sideroblastic anaemia due to disease	0.000	0.981	0.019
D64.0 Hereditary sideroblastic anaemia	0.000	0.981	0.019
E88.8 Other specified metabolic disorders	0.019	0.981	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.019	0.981	0.000
E70 Disorders of aromatic amino-acid metabolism	0.019	0.981	0.000
E73 Lactose intolerance	0.019	0.981	0.000
G58.0 Intercostal neuropathy	0.019	0.981	0.000
G51.8 Other disorders of facial nerve	0.019	0.981	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.019	0.981	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.019	0.981	0.000
G37.5 Concentric sclerosis [Balo]	0.019	0.981	0.000
G37.4 Subacute necrotising myelitis	0.019	0.981	0.000
G37.2 Central pontine myelinolysis	0.019	0.981	0.000
G37.1 Central demyelination of corpus callosum	0.019	0.981	0.000
G37.0 Diffuse sclerosis	0.019	0.981	0.000
G35 Multiple sclerosis	0.019	0.981	0.000
E72 Other disorders of amino-acid metabolism	0.019	0.981	0.000
G50.9 Disorder of trigeminal nerve, unspecified	0.019	0.981	0.000
G51.4 Facial myokymia	0.019	0.981	0.000
G51.2 Melkersson's syndrome	0.019	0.981	0.000
G51.1 Geniculate ganglionitis	0.019	0.981	0.000
E84 Cystic fibrosis	0.019	0.981	0.000
G52.9 Cranial nerve disorder, unspecified	0.018	0.981	0.000
O63.1 Prolonged second stage (of labour)	0.018	0.982	0.000
G58.7 Mononeuritis multiplex	0.018	0.982	0.000
G93.6 Cerebral oedema	0.018	0.982	0.000
G54.6 Phantom limb syndrome with pain	0.018	0.982	0.000
E80.1 Porphyria cutanea tarda	0.018	0.982	0.000
G11.4 Hereditary spastic paraplegia	0.018	0.982	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.018	0.982	0.000
G90.8 Other disorders of autonomic nervous system	0.018	0.982	0.000
G50.8 Other disorders of trigeminal nerve	0.018	0.982	0.000
E77 Disorders of glycoprotein metabolism	0.018	0.982	0.000
E76 Disorders of glycosaminoglycan metabolism	0.018	0.982	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.018	0.982	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.018	0.982	0.000
E85.8 Other amyloidosis	0.018	0.982	0.000
G24.9 Dystonia, unspecified	0.018	0.982	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.018	0.982	0.000
G91.1 Obstructive hydrocephalus	0.017	0.983	0.000
N39.1 Persistent proteinuria, unspecified	0.017	0.983	0.000
G82.5 Tetraplegia, unspecified	0.017	0.983	0.000
G53.8 Other cranial nerve disorders in other diseases classified elsewhere	0.017	0.983	0.000
G53.3 Multiple cranial nerve palsies in neoplastic disease	0.017	0.983	0.000
G53.2 Multiple cranial nerve palsies in sarcoidosis	0.017	0.983	0.000
G53.1 Multiple cranial nerve palsies in infectious and parasitic diseases classified elsewhere	0.017	0.983	0.000
C66 Malignant neoplasm of ureter	0.017	0.983	0.000
G54.4 Lumbosacral root disorders, not elsewhere classified	0.017	0.983	0.000
E88.3 Tumour lysis syndrome	0.017	0.983	0.000
C68.0 Urethra	0.017	0.983	0.000
G61.1 Serum neuropathy	0.017	0.983	0.000
E85.9 Amyloidosis, unspecified	0.017	0.983	0.000
C68.8 Overlapping lesion of urinary organs	0.017	0.983	0.000
C68.1 Paraurethral glands	0.017	0.983	0.000
Z75 Problems related to medical facilities and other health care	0.017	0.983	0.000
G93.9 Disorder of brain, unspecified	0.017	0.983	0.000
Z72 Problems related to lifestyle	0.017	0.983	0.000
E74 Other disorders of carbohydrate metabolism	0.017	0.983	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.983	0.017
C68.9 Urinary organ, unspecified	0.017	0.983	0.000
G90.3 Multisystem degeneration	0.017	0.983	0.000
G11.1 Early-onset cerebellar ataxia	0.016	0.983	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.017	0.983	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.016	0.983	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.016	0.983	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.016	0.983	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.016	0.983	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.016	0.983	0.000
G63.1 Polyneuropathy in neoplastic disease	0.016	0.983	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.016	0.983	0.000
D64.8 Other specified anaemias	0.000	0.984	0.016
N39.9 Disorder of urinary system, unspecified	0.016	0.984	0.000
G57 Mononeuropathies of lower limb	0.016	0.984	0.000
G11.8 Other hereditary ataxias	0.016	0.984	0.000
G11.3 Cerebellar ataxia with defective DNA repair	0.016	0.984	0.000
G11.2 Late-onset cerebellar ataxia	0.016	0.984	0.000
G11.0 Congenital nonprogressive ataxia	0.016	0.984	0.000
G72.4 Inflammatory myopathy, not elsewhere classified	0.016	0.984	0.000
G93.4 Encephalopathy, unspecified	0.016	0.984	0.000
E80.2 Other porphyria	0.016	0.984	0.000
G50.1 Atypical facial pain	0.016	0.984	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.016	0.984	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.016	0.984	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.016	0.984	0.000
G12 Spinal muscular atrophy and related syndromes	0.016	0.984	0.000
G58.9 Mononeuropathy, unspecified	0.016	0.984	0.000
E85.4 Organ-limited amyloidosis	0.016	0.984	0.000
E79 Disorders of purine and pyrimidine metabolism	0.016	0.984	0.000
G82.3 Flaccid tetraplegia	0.016	0.984	0.000
G82.0 Flaccid paraplegia	0.016	0.984	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.016	0.984	0.000
G11.9 Hereditary ataxia, unspecified	0.016	0.984	0.000
G81 Hemiplegia	0.016	0.984	0.000
G97.8 Other postprocedural disorders of nervous system	0.016	0.984	0.000
G36.9 Acute disseminated demyelination, unspecified	0.016	0.984	0.000
G36.8 Other specified acute disseminated demyelination	0.016	0.984	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.016	0.984	0.000
G30.8 Other Alzheimer's disease	0.016	0.984	0.000
G90.2 Horner's syndrome	0.016	0.984	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.015	0.984	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.015	0.984	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.015	0.984	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.015	0.984	0.000
E85.3 Secondary systemic amyloidosis	0.015	0.984	0.000
G63.2 Diabetic polyneuropathy	0.015	0.985	0.000
G82.4 Spastic tetraplegia	0.015	0.985	0.000
Z76 Persons encountering health services in other circumstances	0.015	0.985	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.015	0.985	0.000
G93.5 Compression of brain	0.015	0.985	0.000
G70 Myasthenia gravis and other myoneural disorders	0.015	0.985	0.000
E70.3 Albinism	0.015	0.985	0.000
Z72.1 Alcohol use	0.015	0.985	0.000
G80 Infantile cerebral palsy	0.015	0.985	0.000
G36.0 Neuromyelitis optica [Devic]	0.015	0.985	0.000
E73.9 Lactose intolerance, unspecified	0.015	0.985	0.000
G72.1 Alcoholic myopathy	0.015	0.985	0.000
G72.8 Other specified myopathies	0.015	0.985	0.000
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere	0.015	0.985	0.000
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema	0.015	0.985	0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease	0.015	0.985	0.000
G93.7 Reye's syndrome	0.015	0.985	0.000
G41 Status epilepticus	0.015	0.985	0.000
G30.0 Alzheimer's disease with early onset	0.015	0.985	0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy	0.015	0.985	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.015	0.985	0.000
E80.5 Crigler-Najjar syndrome	0.015	0.985	0.000
E80.3 Defects of catalase and peroxydase	0.015	0.985	0.000
E80.0 Hereditary erythropoietic porphyria	0.015	0.985	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.015	0.985	0.000
E75.2 Other sphingolipidosis	0.015	0.985	0.000
G30.1 Alzheimer's disease with late onset	0.015	0.985	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.014	0.985	0.001
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.014	0.985	0.000
Z76.8 Persons encountering health services in other specified circumstances	0.015	0.985	0.000
G40.5 Special epileptic syndromes	0.014	0.985	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.014	0.986	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.014	0.986	0.000
G72.3 Periodic paralysis	0.014	0.986	0.000
G72.2 Myopathy due to other toxic agents	0.014	0.986	0.000
E84.9 Cystic fibrosis, unspecified	0.014	0.986	0.000
N39.4 Other specified urinary incontinence	0.014	0.986	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.014	0.986	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.014	0.986	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.014	0.986	0.000
E70.2 Disorders of tyrosine metabolism	0.014	0.986	0.000
E70.1 Other hyperphenylalaninaemias	0.014	0.986	0.000
E70.0 Classical phenylketonuria	0.014	0.986	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.014	0.986	0.000
E73.8 Other lactose intolerance	0.014	0.986	0.000
E73.1 Secondary lactase deficiency	0.014	0.986	0.000
E73.0 Congenital lactase deficiency	0.014	0.986	0.000
E80.6 Other disorders of bilirubin metabolism	0.014	0.986	0.000
E75.5 Other lipid storage disorders	0.014	0.986	0.000
E75.6 Lipid storage disorder, unspecified	0.014	0.986	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.014	0.986	0.000
E75.3 Sphingolipidosis, unspecified	0.014	0.986	0.000
E75.1 Other gangliosidosis	0.014	0.986	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations