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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9468926
log Bayes Factor = 53.762
Chromosome 6   position 31,260,218  (GRCh37) Explore rs9468926 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
R31 Unspecified haematuria
0.998 0.002 0.000
L40 Psoriasis
0.000 0.002 0.998
L40.5 Arthropathic psoriasis
0.000 0.004 0.996
L40.0 Psoriasis vulgaris
0.000 0.098 0.902
L40.1 Generalised pustular psoriasis
0.000 0.171 0.829
E03 Other hypothyroidism
0.000 0.177 0.823
E03.8 Other specified hypothyroidism
0.000 0.252 0.748
L40.3 Pustulosis palmaris et plantaris
0.000 0.277 0.723
L40.2 Acrodermatitis continua
0.000 0.284 0.716
K90 Intestinal malabsorption
0.000 0.289 0.711
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.291 0.709
L40.8 Other psoriasis
0.000 0.303 0.697
L40.4 Guttate psoriasis
0.000 0.408 0.591
E03.5 Myxoedema coma
0.000 0.410 0.590
E03.4 Atrophy of thyroid (acquired)
0.000 0.410 0.590
E03.3 Postinfectious hypothyroidism
0.000 0.410 0.590
K90.9 Intestinal malabsorption, unspecified
0.000 0.435 0.565
K75 Other inflammatory liver diseases
0.000 0.437 0.563
K70 Alcoholic liver disease
0.000 0.441 0.559
K70-K77 Diseases of liver
0.000 0.441 0.559
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.447 0.553
K75.8 Other specified inflammatory liver diseases
0.000 0.449 0.551
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.451 0.549
K75.4 Autoimmune hepatitis
0.000 0.472 0.528
K70.1 Alcoholic hepatitis
0.000 0.478 0.522
K90.8 Other intestinal malabsorption
0.000 0.479 0.520
K70.4 Alcoholic hepatic failure
0.000 0.481 0.519
K75.0 Abscess of liver
0.000 0.483 0.517
E03.1 Congenital hypothyroidism without goitre
0.000 0.487 0.513
K90.3 Pancreatic steatorrhoea
0.000 0.490 0.510
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.490 0.510
K90.1 Tropical sprue
0.000 0.490 0.510
K72 Hepatic failure, not elsewhere classified
0.000 0.500 0.500
K70.0 Alcoholic fatty liver
0.000 0.502 0.498
K73 Chronic hepatitis, not elsewhere classified
0.000 0.510 0.490
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.516 0.484
G35 Multiple sclerosis
0.000 0.530 0.470
K72.9 Hepatic failure, unspecified
0.000 0.560 0.440
K72.0 Acute and subacute hepatic failure
0.000 0.571 0.429
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.577 0.423
K70.3 Alcoholic cirrhosis of liver
0.000 0.580 0.420
K73.9 Chronic hepatitis, unspecified
0.000 0.587 0.413
K75.2 Nonspecific reactive hepatitis
0.000 0.596 0.404
K75.1 Phlebitis of portal vein
0.000 0.596 0.404
K77 Liver disorders in diseases classified elsewhere
0.000 0.599 0.401
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.605 0.395
K74 Fibrosis and cirrhosis of liver
0.000 0.612 0.388
K74.0 Hepatic fibrosis
0.000 0.639 0.361
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.648 0.352
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.648 0.352
K90-K93 Other diseases of the digestive system
0.000 0.665 0.335
K71 Toxic liver disease
0.000 0.667 0.332
K51 Ulcerative colitis
0.000 0.686 0.314
Chapter XI Diseases of the digestive system
0.000 0.690 0.310
K51.8 Other ulcerative colitis
0.000 0.691 0.309
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.693 0.307
K72.1 Chronic hepatic failure
0.000 0.696 0.304
K50-K52 Noninfective enteritis and colitis
0.000 0.697 0.303
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.700 0.300
E00-E07 Disorders of thyroid gland
0.000 0.701 0.299
K75.9 Inflammatory liver disease, unspecified
0.000 0.707 0.293
K70.9 Alcoholic liver disease, unspecified
0.000 0.712 0.288
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.712 0.287
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.712 0.287
K51.4 Pseudopolyposis of colon
0.000 0.717 0.283
K74.4 Secondary biliary cirrhosis
0.000 0.722 0.278
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.722 0.278
K74.5 Biliary cirrhosis, unspecified
0.000 0.725 0.275
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.726 0.274
L40-L45 Papulosquamous disorders
0.000 0.737 0.262
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.738 0.262
K51.9 Ulcerative colitis, unspecified
0.000 0.740 0.260
K74.1 Hepatic sclerosis
0.000 0.741 0.259
E05.9 Thyrotoxicosis, unspecified
0.000 0.744 0.256
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.751 0.249
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.760 0.240
K71.9 Toxic liver disease, unspecified
0.000 0.761 0.238
K71.8 Toxic liver disease with other disorders of liver
0.000 0.761 0.238
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.761 0.238
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.761 0.238
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.761 0.238
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.761 0.238
K71.2 Toxic liver disease with acute hepatitis
0.000 0.761 0.238
K71.0 Toxic liver disease with cholestasis
0.000 0.761 0.238
E07 Other disorders of thyroid
0.000 0.763 0.237
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.770 0.229
K51.5 Mucosal proctocolitis
0.000 0.772 0.228
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.774 0.226
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.781 0.219
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.785 0.215
E00 Congenital iodine-deficiency syndrome
0.000 0.785 0.215
E07.8 Other specified disorders of thyroid
0.000 0.786 0.214
E05.5 Thyroid crisis or storm
0.000 0.803 0.197
E05.4 Thyrotoxicosis factitia
0.000 0.803 0.197
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.803 0.197
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.803 0.197
L42 Pityriasis rosea
0.000 0.804 0.196
K35-K38 Diseases of appendix
0.000 0.805 0.195
K74.3 Primary biliary cirrhosis
0.000 0.808 0.192
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.810 0.190
L44 Other papulosquamous disorders
0.000 0.811 0.188
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.811 0.188
G30-G32 Other degenerative diseases of the nervous system
0.000 0.813 0.187
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.001 0.815 0.184
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.818 0.182
Chapter VI Diseases of the nervous system
0.000 0.818 0.182
D64.9 Anaemia, unspecified
0.000 0.820 0.180
G36 Other acute disseminated demyelination
0.000 0.825 0.175
D64 Other anaemias
0.000 0.827 0.173
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.827 0.172
K93.1 Megacolon in Chagas' disease
0.000 0.827 0.172
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.827 0.172
E07.1 Dyshormogenetic goitre
0.000 0.830 0.170
E07.0 Hypersecretion of calcitonin
0.000 0.830 0.170
G31.2 Degeneration of nervous system due to alcohol
0.000 0.831 0.169
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.833 0.167
L41 Parapsoriasis
0.001 0.835 0.164
G70-G73 Diseases of myoneural junction and muscle
0.000 0.839 0.161
G31.8 Other specified degenerative diseases of nervous system
0.000 0.842 0.158
D64.8 Other specified anaemias
0.000 0.843 0.157
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.843 0.157
E06 Thyroiditis
0.000 0.844 0.156
K74.6 Other and unspecified cirrhosis of liver
0.000 0.844 0.156
D60-D64 Aplastic and other anaemias
0.000 0.845 0.155
K36 Other appendicitis
0.000 0.845 0.154
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.846 0.154
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.846 0.154
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.846 0.154
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.846 0.154
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.846 0.154
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.846 0.154
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.846 0.154
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.846 0.154
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.847 0.153
G30 Alzheimer's disease
0.000 0.848 0.152
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.848 0.152
G31.0 Circumscribed brain atrophy
0.000 0.848 0.152
D61 Other aplastic anaemias
0.000 0.850 0.150
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.852 0.148
D61.9 Aplastic anaemia, unspecified
0.000 0.852 0.148
G37 Other demyelinating diseases of central nervous system
0.000 0.855 0.145
D50-D53 Nutritional anaemias
0.000 0.856 0.144
K38 Other diseases of appendix
0.000 0.856 0.144
D50 Iron deficiency anaemia
0.000 0.859 0.141
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.860 0.140
K35 Acute appendicitis
0.000 0.861 0.139
K35.8 Acute appendicitis, other and unspecified
0.000 0.863 0.137
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.864 0.136
L44.9 Papulosquamous disorder, unspecified
0.000 0.864 0.135
L44.8 Other specified papulosquamous disorders
0.000 0.864 0.135
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.864 0.135
L44.3 Lichen ruber moniliformis
0.000 0.864 0.135
L44.2 Lichen striatus
0.000 0.864 0.135
L44.1 Lichen nitidus
0.000 0.864 0.135
L44.0 Pityriasis rubra pilaris
0.000 0.864 0.135
G30.9 Alzheimer's disease, unspecified
0.000 0.866 0.134
E05.8 Other thyrotoxicosis
0.000 0.866 0.133
G70 Myasthenia gravis and other myoneural disorders
0.000 0.866 0.133
G61 Inflammatory polyneuropathy
0.000 0.869 0.131
D50.9 Iron deficiency anaemia, unspecified
0.000 0.869 0.131
G62 Other polyneuropathies
0.000 0.870 0.130
D51 Vitamin B12 deficiency anaemia
0.000 0.870 0.130
G06 Intracranial and intraspinal abscess and granuloma
0.000 0.871 0.129
G09 Sequelae of inflammatory diseases of central nervous system
0.000 0.872 0.128
G72 Other myopathies
0.000 0.872 0.128
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.874 0.126
G36.9 Acute disseminated demyelination, unspecified
0.000 0.874 0.126
G36.8 Other specified acute disseminated demyelination
0.000 0.874 0.126
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.874 0.126
E06.3 Autoimmune thyroiditis
0.000 0.875 0.125
D64.4 Congenital dyserythropoietic anaemia
0.000 0.876 0.124
D64.3 Other sideroblastic anaemias
0.000 0.876 0.124
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.876 0.124
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.876 0.124
D64.0 Hereditary sideroblastic anaemia
0.000 0.876 0.124
G71 Primary disorders of muscles
0.000 0.876 0.124
G60 Hereditary and idiopathic neuropathy
0.000 0.877 0.122
D50.8 Other iron deficiency anaemias
0.000 0.878 0.122
G61.8 Other inflammatory polyneuropathies
0.000 0.880 0.120
K65-K67 Diseases of peritoneum
0.000 0.880 0.120
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.881 0.119
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.881 0.119
G70.0 Myasthenia gravis
0.000 0.881 0.119
L41.9 Parapsoriasis, unspecified
0.001 0.882 0.118
L41.8 Other parapsoriasis
0.001 0.882 0.118
L41.5 Retiform parapsoriasis
0.001 0.882 0.118
L41.4 Large plaque parapsoriasis
0.001 0.882 0.118
L41.3 Small plaque parapsoriasis
0.001 0.882 0.118
L41.2 Lymphomatoid papulosis
0.001 0.882 0.118
L41.0 Pityriasis lichenoides et varioliformis acuta
0.001 0.882 0.118
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.000 0.882 0.118
G01 Meningitis in bacterial diseases classified elsewhere
0.000 0.884 0.116
K38.8 Other specified diseases of appendix
0.000 0.884 0.116
K52 Other non-infective gastro-enteritis and colitis
0.000 0.884 0.116
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.884 0.115
K35.1 Acute appendicitis with peritoneal abscess
0.000 0.885 0.115
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.000 0.885 0.115
G62.9 Polyneuropathy, unspecified
0.000 0.885 0.115
G00 Bacterial meningitis, not elsewhere classified
0.000 0.885 0.115
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.886 0.114
G03 Meningitis due to other and unspecified causes
0.000 0.886 0.114
D52 Folate deficiency anaemia
0.000 0.887 0.113
G36.0 Neuromyelitis optica [Devic]
0.000 0.887 0.112
G64 Other disorders of peripheral nervous system
0.000 0.887 0.112
E06.4 Drug-induced thyroiditis
0.000 0.888 0.112
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.888 0.112
E06.0 Acute thyroiditis
0.000 0.888 0.112
D53 Other nutritional anaemias
0.000 0.888 0.112
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.888 0.111
G72.9 Myopathy, unspecified
0.000 0.890 0.110
E07.9 Disorder of thyroid, unspecified
0.000 0.890 0.110
D55-D59 Haemolytic anaemias
0.000 0.890 0.110
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.000 0.890 0.110
G30.1 Alzheimer's disease with late onset
0.000 0.891 0.109
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.892 0.108
D61.8 Other specified aplastic anaemias
0.000 0.892 0.107
D61.3 Idiopathic aplastic anaemia
0.000 0.892 0.107
D61.2 Aplastic anaemia due to other external agents
0.000 0.892 0.107
G71.3 Mitochondrial myopathy, not elsewhere classified
0.000 0.892 0.107
E06.5 Other chronic thyroiditis
0.000 0.894 0.106
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.000 0.894 0.106
G06.0 Intracranial abscess and granuloma
0.000 0.894 0.106
G62.1 Alcoholic polyneuropathy
0.000 0.895 0.105
G37.5 Concentric sclerosis [Balo]
0.000 0.896 0.104
G37.4 Subacute necrotising myelitis
0.000 0.896 0.104
G37.2 Central pontine myelinolysis
0.000 0.896 0.104
G37.1 Central demyelination of corpus callosum
0.000 0.896 0.104
G37.0 Diffuse sclerosis
0.000 0.896 0.104
G30.8 Other Alzheimer's disease
0.000 0.896 0.104
K38.1 Appendicular concretions
0.000 0.896 0.104
K38.3 Fistula of appendix
0.000 0.897 0.103
K38.2 Diverticulum of appendix
0.000 0.897 0.103
K38.0 Hyperplasia of appendix
0.000 0.897 0.103
D61.0 Constitutional aplastic anaemia
0.000 0.897 0.103
G06.1 Intraspinal abscess and granuloma
0.000 0.897 0.103
G60.0 Hereditary motor and sensory neuropathy
0.000 0.897 0.103
D50.1 Sideropenic dysphagia
0.000 0.898 0.102
G30.0 Alzheimer's disease with early onset
0.000 0.900 0.100
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.000 0.900 0.099
D61.1 Drug-induced aplastic anaemia
0.000 0.901 0.099
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.901 0.099
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.000 0.901 0.099
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.903 0.097
G70.8 Other specified myoneural disorders
0.000 0.904 0.096
G70.2 Congenital and developmental myasthenia
0.000 0.904 0.096
G70.1 Toxic myoneural disorders
0.000 0.904 0.096
G72.8 Other specified myopathies
0.000 0.905 0.095
L41.1 Pityriasis lichenoides chronica
0.001 0.905 0.094
G61.1 Serum neuropathy
0.000 0.906 0.094
D80-D89 Certain disorders involving the immune mechanism
0.000 0.906 0.094
D59 Acquired haemolytic anaemia
0.000 0.907 0.093
G62.2 Polyneuropathy due to other toxic agents
0.000 0.907 0.093
D51.2 Transcobalamin II deficiency
0.000 0.907 0.093
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.907 0.093
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.907 0.093
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.000 0.907 0.093
K52.3 Indeterminate colitis
0.000 0.907 0.093
G06.2 Extradural and subdural abscess, unspecified
0.000 0.908 0.092
G62.8 Other specified polyneuropathies
0.000 0.908 0.092
G72.3 Periodic paralysis
0.000 0.908 0.092
G72.2 Myopathy due to other toxic agents
0.000 0.908 0.092
G72.1 Alcoholic myopathy
0.000 0.908 0.092
G00.1 Pneumococcal meningitis
0.000 0.908 0.092
K35.2 Acute appendicitis with generalized peritonitis
0.000 0.908 0.092
D52.9 Folate deficiency anaemia, unspecified
0.000 0.909 0.091
K38.9 Disease of appendix, unspecified
0.000 0.910 0.089
M07.3 Other psoriatic arthropathies
0.000 0.910 0.089
G83 Other paralytic syndromes
0.000 0.910 0.089
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.911 0.089
G71.9 Primary disorder of muscle, unspecified
0.000 0.911 0.089
G71.8 Other primary disorders of muscles
0.000 0.911 0.089
G71.2 Congenital myopathies
0.000 0.911 0.089
G71.1 Myotonic disorders
0.000 0.911 0.089
G63 Polyneuropathy in diseases classified elsewhere
0.000 0.911 0.089
D53.9 Nutritional anaemia, unspecified
0.000 0.912 0.088
E06.9 Thyroiditis, unspecified
0.000 0.912 0.088
G72.0 Drug-induced myopathy
0.000 0.912 0.088
G60.3 Idiopathic progressive neuropathy
0.000 0.912 0.088
G60.2 Neuropathy in association with hereditary ataxia
0.000 0.912 0.088
G60.1 Refsum's disease
0.000 0.912 0.088
# Top node
0.000 0.914 0.086
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.000 0.914 0.086
G03.9 Meningitis, unspecified
0.000 0.914 0.086
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.914 0.086
G60.8 Other hereditary and idiopathic neuropathies
0.000 0.914 0.086
G61.0 Guillain-Barre syndrome
0.000 0.915 0.085
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.915 0.085
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.000 0.915 0.085
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.000 0.915 0.085
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.000 0.915 0.085
G70.9 Myoneural disorder, unspecified
0.000 0.915 0.085
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.916 0.084
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.916 0.084
G72.4 Inflammatory myopathy, not elsewhere classified
0.000 0.916 0.084
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.916 0.084
G73.7 Myopathy other diseases classified elsewhere
0.000 0.917 0.083
G73.6 Myopathy in metabolic diseases
0.000 0.917 0.083
G73.5 Myopathy in endocrine diseases
0.000 0.917 0.083
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere
0.000 0.917 0.083
G73.3 Myasthenic syndromes in other diseases classified elsewhere
0.000 0.917 0.083
G73.2 Other myasthenic syndromes in neoplastic disease
0.000 0.917 0.083
G73.1 Eaton-Lambert syndrome
0.000 0.917 0.083
G73.0 Myasthenic syndromes in endocrine diseases
0.000 0.917 0.083
G61.9 Inflammatory polyneuropathy, unspecified
0.000 0.917 0.083
G00.8 Other bacterial meningitis
0.000 0.917 0.083
G00.3 Staphylococcal meningitis
0.000 0.917 0.083
G00.2 Streptococcal meningitis
0.000 0.917 0.083
G00.0 Haemophilus meningitis
0.000 0.917 0.083
G60.9 Hereditary and idiopathic neuropathy, unspecified
0.000 0.918 0.082
G03.8 Meningitis due to other specified causes
0.000 0.918 0.082
G03.2 Benign recurrent meningitis [Mollaret]
0.000 0.918 0.082
G03.1 Chronic meningitis
0.000 0.918 0.082
G03.0 Nonpyogenic meningitis
0.000 0.918 0.082
D52.8 Other folate deficiency anaemias
0.000 0.918 0.081
D52.1 Drug-induced folate deficiency anaemia
0.000 0.918 0.081
D52.0 Dietary folate deficiency anaemia
0.000 0.918 0.081
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.919 0.081
D53.8 Other specified nutritional anaemias
0.000 0.920 0.080
D53.2 Scorbutic anaemia
0.000 0.920 0.080
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.920 0.080
D53.0 Protein deficiency anaemia
0.000 0.920 0.080
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.920 0.080
D60.8 Other acquired pure red cell aplasias
0.000 0.920 0.080
D60.1 Transient acquired pure red cell aplasia
0.000 0.920 0.080
D60.0 Chronic acquired pure red cell aplasia
0.000 0.920 0.080
D58 Other hereditary haemolytic anaemias
0.000 0.920 0.080
G83.4 Cauda equina syndrome
0.000 0.920 0.080
D55 Anaemia due to enzyme disorders
0.000 0.921 0.079
D59.1 Other autoimmune haemolytic anaemias
0.000 0.921 0.079
G80 Infantile cerebral palsy
0.000 0.922 0.078
L10-L14 Bullous disorders
0.000 0.922 0.078
K37 Unspecified appendicitis
0.000 0.922 0.078
G00.9 Bacterial meningitis, unspecified
0.000 0.923 0.077
D80 Immunodeficiency with predominantly antibody defects
0.000 0.923 0.077
L50-L54 Urticaria and erythema
0.000 0.924 0.076
G82 Paraplegia and tetraplegia
0.000 0.924 0.076
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.925 0.074
E06.1 Subacute thyroiditis
0.001 0.926 0.074
D56 Thalassaemia
0.000 0.926 0.074
L43 Lichen planus
0.001 0.927 0.072
D57 Sickle-cell disorders
0.000 0.927 0.073
K51.2 Ulcerative (chronic) proctitis
0.000 0.927 0.073
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.927 0.072
G81 Hemiplegia
0.000 0.928 0.072
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.000 0.928 0.071
G02.1 Meningitis in mycoses
0.000 0.928 0.071
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.929 0.071
G71.0 Muscular dystrophy
0.000 0.929 0.070
G04 Encephalitis, myelitis and encephalomyelitis
0.000 0.930 0.070
L13 Other bullous disorders
0.000 0.931 0.069
L50 Urticaria
0.000 0.931 0.069
G83.9 Paralytic syndrome, unspecified
0.000 0.932 0.068
D81 Combined immunodeficiencies
0.000 0.932 0.068
D83 Common variable immunodeficiency
0.000 0.932 0.068
D59.8 Other acquired haemolytic anaemias
0.000 0.933 0.067
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.933 0.067
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.933 0.067
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.933 0.067
D59.3 Haemolytic-uraemic syndrome
0.000 0.933 0.067
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.933 0.067
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.933 0.067
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.933 0.067
E50-E64 Other nutritional deficiencies
0.000 0.933 0.067
E53.8 Deficiency of other specified B group vitamins
0.000 0.934 0.066
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.934 0.066
E53 Deficiency of other B group vitamins
0.000 0.934 0.066
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.934 0.065
D62 Acute posthaemorrhagic anaemia
0.000 0.935 0.065
G82.1 Spastic paraplegia
0.000 0.935 0.065
M07.38 Other psoriatic arthropathies (Other)
0.000 0.936 0.064
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.936 0.064
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.936 0.064
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.936 0.064
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.936 0.064
G83.5 Locked-in syndrome
0.000 0.936 0.064
G83.3 Monoplegia, unspecified
0.000 0.936 0.064
G83.0 Diplegia of upper limbs
0.000 0.936 0.064
G63.8 Polyneuropathy in other diseases classified elsewhere
0.000 0.936 0.064
G63.6 Polyneuropathy in other musculoskeletal disorders
0.000 0.936 0.064
G63.5 Polyneuropathy in systemic connective tissue disorders
0.000 0.936 0.064
G63.4 Polyneuropathy in nutritional deficiency
0.000 0.936 0.064
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.000 0.936 0.064
G63.1 Polyneuropathy in neoplastic disease
0.000 0.936 0.064
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.000 0.936 0.064
G12 Spinal muscular atrophy and related syndromes
0.000 0.936 0.064
K35.3 Acute appendicitis with localized peritonitis
0.000 0.936 0.064
D58.0 Hereditary spherocytosis
0.000 0.937 0.063
L13.0 Dermatitis herpetiformis
0.000 0.937 0.063
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.937 0.063
G62.0 Drug-induced polyneuropathy
0.000 0.937 0.062
L52 Erythema nodosum
0.000 0.938 0.062
L12 Pemphigoid
0.000 0.938 0.062
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere
0.000 0.938 0.062
K67.3 Tuberculous peritonitis
0.000 0.938 0.062
K67.2 Syphilitic peritonitis
0.000 0.938 0.062
K67.1 Gonococcal peritonitis
0.000 0.938 0.062
K67.0 Chlamydial peritonitis
0.000 0.938 0.062
G83.1 Monoplegia of lower limb
0.000 0.938 0.062
D84 Other immunodeficiencies
0.000 0.938 0.062
G80.2 Infantile hemiplegia
0.000 0.938 0.062
D82 Immunodeficiency associated with other major defects
0.000 0.938 0.062
G02.0 Meningitis in viral diseases classified elsewhere
0.000 0.938 0.061
L50.0 Allergic urticaria
0.000 0.939 0.061
G83.8 Other specified paralytic syndromes
0.000 0.939 0.061
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.939 0.060
D89.1 Cryoglobulinaemia
0.000 0.940 0.060
G81.1 Spastic hemiplegia
0.000 0.941 0.059
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.941 0.059
K66 Other disorders of peritoneum
0.000 0.941 0.059
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.941 0.058
D89.3 Immune reconstitution syndrome
0.000 0.941 0.058
G80.0 Spastic cerebral palsy
0.000 0.942 0.058
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.942 0.058
D58.1 Hereditary elliptocytosis
0.000 0.942 0.058
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.942 0.058
D56.1 Beta thalassaemia
0.000 0.942 0.057
D58.9 Hereditary haemolytic anaemia, unspecified
0.000 0.943 0.057
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.943 0.057
D55.8 Other anaemias due to enzyme disorders
0.000 0.943 0.057
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.943 0.057
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.943 0.057
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.943 0.057
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.943 0.057
L50.1 Idiopathic urticaria
0.000 0.943 0.057
G82.4 Spastic tetraplegia
0.000 0.944 0.056
G80.8 Other infantile cerebral palsy
0.000 0.944 0.056
G80.4 Ataxic cerebral palsy
0.000 0.944 0.056
G80.3 Dyskinetic cerebral palsy
0.000 0.944 0.056
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.944 0.056
L14 Bullous disorders in diseases classified elsewhere
0.000 0.944 0.056
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.944 0.056
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.945 0.055
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.945 0.055
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.945 0.055
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.945 0.055
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.945 0.055
L11 Other acantholytic disorders
0.000 0.945 0.055
L54 Erythema in diseases classified elsewhere
0.000 0.945 0.055
G82.3 Flaccid tetraplegia
0.000 0.945 0.055
G82.0 Flaccid paraplegia
0.000 0.945 0.055
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.945 0.055
N39.3 Stress incontinence
0.055 0.945 0.000
K76 Other diseases of liver
0.000 0.946 0.054
G11 Hereditary ataxia
0.000 0.946 0.054
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.946 0.054
G80.1 Spastic diplegia
0.000 0.947 0.053
D56.9 Thalassaemia, unspecified
0.000 0.947 0.053
D56.8 Other thalassaemias
0.000 0.947 0.053
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.947 0.053
D56.2 Delta-beta thalassaemia
0.000 0.947 0.053
D56.0 Alpha thalassaemia
0.000 0.947 0.053
G82.5 Tetraplegia, unspecified
0.000 0.947 0.053
G90-G99 Other disorders of the nervous system
0.000 0.947 0.053
D58.2 Other haemoglobinopathies
0.000 0.947 0.053
G14 Postpolio syndrome
0.000 0.947 0.052
L43.3 Subacute (active) lichen planus
0.001 0.947 0.051
L43.2 Lichenoid drug reaction
0.001 0.947 0.051
L43.1 Bullous lichen planus
0.001 0.947 0.051
L43.0 Hypertrophic lichen planus
0.001 0.947 0.051
D57.8 Other sickle-cell disorders
0.000 0.947 0.052
D57.3 Sickle-cell trait
0.000 0.947 0.052
D57.2 Double heterozygous sickling disorders
0.000 0.947 0.052
D57.0 Sickle-cell anaemia with crisis
0.000 0.947 0.052
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.000 0.948 0.052
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.001 0.948 0.051
G81.0 Flaccid hemiplegia
0.000 0.948 0.052
L10 Pemphigus
0.000 0.948 0.052
L53 Other erythematous conditions
0.000 0.948 0.052
E40-E46 Malnutrition
0.000 0.949 0.051
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.000 0.949 0.050
G04.1 Tropical spastic paraplegia
0.000 0.949 0.050
K52.0 Gastro-enteritis and colitis due to radiation
0.000 0.950 0.050
L13.9 Bullous disorder, unspecified
0.000 0.950 0.050
L13.8 Other specified bullous disorders
0.000 0.950 0.050
L13.1 Subcorneal pustular dermatitis
0.000 0.950 0.050
L50.6 Contact urticaria
0.000 0.950 0.049
L50.5 Cholinergic urticaria
0.000 0.950 0.049
L50.4 Vibratory urticaria
0.000 0.950 0.049
L50.3 Dermatographic urticaria
0.000 0.950 0.049
L50.2 Urticaria due to cold and heat
0.000 0.950 0.049
L12.1 Cicatricial pemphigoid
0.000 0.951 0.049
G12.2 Motor neuron disease
0.000 0.951 0.049
Chapter XXII Codes for special purposes
0.000 0.951 0.049
G93 Other disorders of brain
0.000 0.951 0.049
L50.8 Other urticaria
0.000 0.951 0.049
D81.9 Combined immunodeficiency, unspecified
0.000 0.951 0.049
D81.8 Other combined immunodeficiencies
0.000 0.951 0.049
D81.7 Major histocompatibility complex class II deficiency
0.000 0.951 0.049
D81.6 Major histocompatibility complex class I deficiency
0.000 0.951 0.049
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.951 0.049
D81.4 Nezelof's syndrome
0.000 0.951 0.049
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.951 0.049
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.951 0.049
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.951 0.049
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.951 0.049
D83.8 Other common variable immunodeficiencies
0.000 0.951 0.049
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.951 0.049

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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