TreeWAS – Variant ID: rs9472135

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.226	0.774
E03 Other hypothyroidism	0.000	0.463	0.536
E03.8 Other specified hypothyroidism	0.000	0.510	0.490
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.594	0.406
E03.5 Myxoedema coma	0.000	0.615	0.385
E03.4 Atrophy of thyroid (acquired)	0.000	0.615	0.385
E03.3 Postinfectious hypothyroidism	0.000	0.615	0.385
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.626	0.374
E03.1 Congenital hypothyroidism without goitre	0.000	0.640	0.360
N75.1 Abscess of Bartholin's gland	0.000	0.931	0.069
N75 Diseases of Bartholin's gland	0.000	0.942	0.058
N70.9 Salpingitis and oophoritis, unspecified	0.000	0.945	0.055
N70 Salpingitis and oophoritis	0.000	0.945	0.055
N70-N77 Inflammatory diseases of female pelvic organs	0.000	0.947	0.053
N76 Other inflammation of vagina and vulva	0.000	0.948	0.052
N76.0 Acute vaginitis	0.000	0.953	0.047
N76.4 Abscess of vulva	0.000	0.954	0.046
N70.0 Acute salpingitis and oophoritis	0.000	0.954	0.046
N76.1 Subacute and chronic vaginitis	0.000	0.958	0.042
N75.9 Disease of Bartholin's gland, unspecified	0.000	0.958	0.042
N75.8 Other diseases of Bartholin's gland	0.000	0.958	0.042
N76.8 Other specified inflammation of vagina and vulva	0.000	0.959	0.041
N76.5 Ulceration of vagina	0.000	0.959	0.041
N70.1 Chronic salpingitis and oophoritis	0.000	0.959	0.041
N71 Inflammatory disease of uterus, except cervix	0.000	0.960	0.040
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.000	0.961	0.038
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.000	0.963	0.037
N75.0 Cyst of Bartholin's gland	0.000	0.965	0.035
N76.6 Ulceration of vulva	0.000	0.966	0.034
N76.3 Subacute and chronic vulvitis	0.000	0.968	0.032
N71.0 Acute inflammatory disease of uterus	0.000	0.969	0.031
N76.2 Acute vulvitis	0.000	0.969	0.031
N71.9 Inflammatory disease of uterus, unspecified	0.000	0.971	0.029
Z00.5 Examination of potential donor of organ and tissue	0.000	0.971	0.029
N74.8 Female pelvic inflammatory disorders in other diseases classified elsewhere	0.000	0.972	0.028
N74.4 Female chlamydial pelvic inflammatory disease	0.000	0.972	0.028
N74.3 Female gonococcal pelvic inflammatory disease	0.000	0.972	0.028
N74.2 Female syphilitic pelvic inflammatory disease	0.000	0.972	0.028
N74.1 Female tuberculous pelvic inflammatory disease	0.000	0.972	0.028
N74.0 Tuberculous infection of cervix uteri	0.000	0.972	0.028
N71.1 Chronic inflammatory disease of uterus	0.000	0.972	0.028
N77.8 Vulvovaginal ulceration and inflammation in other diseases classified elsewhere	0.000	0.973	0.027
N77.0 Ulceration of vulva in infectious and parasitic diseases classified elsewhere	0.000	0.973	0.027
N73 Other female pelvic inflammatory diseases	0.000	0.974	0.026
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.000	0.974	0.026
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.974	0.026
Z00.6 Examination for normal comparison and control in clinical research programme	0.000	0.975	0.025
Z00.4 General psychiatric examination, not elsewhere classified	0.000	0.975	0.025
I10 Essential (primary) hypertension	0.000	0.977	0.023
N73.1 Chronic parametritis and pelvic cellulitis	0.000	0.978	0.022
K86 Other diseases of pancreas	0.000	0.981	0.019
K86.1 Other chronic pancreatitis	0.000	0.981	0.019
N73.8 Other specified female pelvic inflammatory diseases	0.000	0.981	0.019
N73.4 Female chronic pelvic peritonitis	0.000	0.981	0.019
N73.3 Female acute pelvic peritonitis	0.000	0.981	0.019
N73.2 Unspecified parametritis and pelvic cellulitis	0.000	0.981	0.019
N73.0 Acute parametritis and pelvic cellulitis	0.000	0.981	0.019
E00-E07 Disorders of thyroid gland	0.000	0.981	0.019
Z00.3 Examination for adolescent development state	0.000	0.981	0.019
Z00.2 Examination for period of rapid growth in childhood	0.000	0.981	0.019
Z00.1 Routine child health examination	0.000	0.981	0.019
Z00.8 Other general examinations	0.000	0.981	0.019
K86.2 Cyst of pancreas	0.000	0.982	0.018
K86.3 Pseudocyst of pancreas	0.000	0.982	0.018
N73.5 Female pelvic peritonitis, unspecified	0.000	0.983	0.017
K86.9 Disease of pancreas, unspecified	0.000	0.983	0.017
Z00.0 General medical examination	0.000	0.983	0.017
K83.8 Other specified diseases of biliary tract	0.000	0.984	0.016
N73.6 Female pelvic peritoneal adhesions	0.000	0.984	0.016
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.985	0.015
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.986	0.014
E00 Congenital iodine-deficiency syndrome	0.000	0.986	0.014
E07 Other disorders of thyroid	0.000	0.987	0.013
K83 Other diseases of biliary tract	0.000	0.987	0.013
J32.9 Chronic sinusitis, unspecified	0.000	0.987	0.013
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.987	0.013
O62 Abnormalities of forces of labour	0.000	0.987	0.013
S22.20 Fracture of sternum (closed)	0.013	0.987	0.000
O62.3 Precipitate labour	0.000	0.988	0.012
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.988	0.012
N20.0 Calculus of kidney	0.012	0.988	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.000	0.988	0.012
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.000	0.988	0.012
O72.0 Third-stage haemorrhage	0.000	0.989	0.011
K85 Acute pancreatitis	0.000	0.989	0.011
O60-O75 Complications of labour and delivery	0.000	0.989	0.011
O69 Labour and delivery complicated by umbilical cord complications	0.000	0.989	0.011
E06 Thyroiditis	0.000	0.989	0.011
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.000	0.989	0.011
K83.9 Disease of biliary tract, unspecified	0.000	0.989	0.011
K83.0 Cholangitis	0.000	0.989	0.011
E07.8 Other specified disorders of thyroid	0.000	0.989	0.011
O62.1 Secondary uterine inertia	0.000	0.989	0.011
K85.1 Biliary acute pancreatitis	0.000	0.989	0.011
O62.2 Other uterine inertia	0.000	0.990	0.010
O64 Obstructed labour due to malposition and malpresentation of foetus	0.000	0.990	0.010
N73.9 Female pelvic inflammatory disease, unspecified	0.000	0.990	0.010
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.990	0.010
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.990	0.010
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.990	0.010
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.990	0.010
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.990	0.010
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.990	0.010
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.990	0.010
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.990	0.010
O75 Other complications of labour and delivery, not elsewhere classified	0.000	0.990	0.010
O72 Postpartum haemorrhage	0.000	0.990	0.010
E07.1 Dyshormogenetic goitre	0.000	0.990	0.010
E07.0 Hypersecretion of calcitonin	0.000	0.990	0.010
O63 Long labour	0.000	0.990	0.010
K83.1 Obstruction of bile duct	0.000	0.990	0.010
K83.3 Fistula of bile duct	0.000	0.990	0.010
K86.8 Other specified diseases of pancreas	0.000	0.990	0.010
N20.2 Calculus of kidney with calculus of ureter	0.010	0.990	0.000
K85.9 Acute pancreatitis, unspecified	0.000	0.991	0.009
O62.9 Abnormality of forces of labour, unspecified	0.000	0.991	0.009
O62.8 Other abnormalities of forces of labour	0.000	0.991	0.009
K85.8 Other acute pancreatitis	0.000	0.991	0.009
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.000	0.991	0.009
O68 Labour and delivery complicated by foetal stress [distress]	0.000	0.991	0.009
K83.5 Biliary cyst	0.000	0.991	0.009
O75.8 Other specified complications of labour and delivery	0.000	0.991	0.009
O63.1 Prolonged second stage (of labour)	0.000	0.991	0.009
N20 Calculus of kidney and ureter	0.009	0.991	0.000
K83.4 Spasm of sphincter of Oddi	0.000	0.991	0.009
K85.0 Idiopathic acute pancreatitis	0.000	0.991	0.009
K08.3 Retained dental root	0.000	0.991	0.009
K83.2 Perforation of bile duct	0.000	0.991	0.009
O75.0 Maternal distress during labour and delivery	0.000	0.991	0.009
E06.9 Thyroiditis, unspecified	0.000	0.991	0.008
O75.2 Pyrexia during labour, not elsewhere classified	0.000	0.991	0.009
K08.8 Other specified disorders of teeth and supporting structures	0.000	0.991	0.009
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.000	0.992	0.008
O69.0 Labour and delivery complicated by prolapse of cord	0.000	0.992	0.008
O74 Complications of anaesthesia during labour and delivery	0.000	0.992	0.008
K85.3 Drug-induced acute pancreatitis	0.000	0.992	0.008
O60 Preterm delivery	0.000	0.992	0.008
O69.5 Labour and delivery complicated by vascular lesion of cord	0.000	0.992	0.008
O69.4 Labour and delivery complicated by vasa praevia	0.000	0.992	0.008
O69.3 Labour and delivery complicated by short cord	0.000	0.992	0.008
E06.4 Drug-induced thyroiditis	0.000	0.992	0.008
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.992	0.008
E06.0 Acute thyroiditis	0.000	0.992	0.008
E07.9 Disorder of thyroid, unspecified	0.000	0.992	0.008
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.000	0.992	0.008
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.000	0.992	0.008
O62.0 Primary inadequate contractions	0.000	0.992	0.008
O63.9 Long labour, unspecified	0.000	0.992	0.008
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.000	0.992	0.008
D68.9 Coagulation defect, unspecified	0.000	0.992	0.008
E06.1 Subacute thyroiditis	0.000	0.992	0.008
O69.2 Labour and delivery complicated by other cord entanglement	0.000	0.992	0.008
O64.5 Obstructed labour due to compound presentation	0.000	0.992	0.008
O64.4 Obstructed labour due to shoulder presentation	0.000	0.992	0.008
O64.3 Obstructed labour due to brow presentation	0.000	0.992	0.008
O64.2 Obstructed labour due to face presentation	0.000	0.992	0.008
K08 Other disorders of teeth and supporting structures	0.000	0.992	0.008
N23 Unspecified renal colic	0.008	0.992	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.000	0.992	0.007
E06.5 Other chronic thyroiditis	0.000	0.992	0.007
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.000	0.992	0.007
O73 Retained placenta and membranes, without haemorrhage	0.000	0.993	0.007
O75.5 Delayed delivery after artificial rupture of membranes	0.000	0.993	0.007
O75.4 Other complications of obstetric surgery and procedures	0.000	0.993	0.007
O75.3 Other infection during labour	0.000	0.993	0.007
O75.1 Shock during or following labour and delivery	0.000	0.993	0.007
O69.8 Labour and delivery complicated by other cord complications	0.000	0.993	0.007
D68 Other coagulation defects	0.000	0.993	0.007
O72.3 Postpartum coagulation defects	0.000	0.993	0.007
O63.2 Delayed delivery of second twin, triplet, etc.	0.000	0.993	0.007
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.000	0.993	0.007
O71 Other obstetric trauma	0.000	0.993	0.007
K85.2 Alcohol-induced acute pancreatitis	0.000	0.993	0.007
S22.2 Fracture of sternum	0.007	0.993	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.000	0.993	0.007
D68.6 Other Thrombophilia	0.000	0.993	0.007
O61 Failed induction of labour	0.000	0.993	0.007
N20-N23 Urolithiasis	0.007	0.993	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.000	0.993	0.007
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.993	0.007
O75.9 Complication of labour and delivery, unspecified	0.000	0.993	0.006
O63.0 Prolonged first stage (of labour)	0.000	0.993	0.007
D68.8 Other specified coagulation defects	0.000	0.994	0.006
K08.9 Disorder of teeth and supporting structures, unspecified	0.000	0.994	0.006
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.000	0.994	0.006
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.000	0.994	0.006
O74.8 Other complications of anaesthesia during labour and delivery	0.000	0.994	0.006
O74.7 Failed or difficult intubation during labour and delivery	0.000	0.994	0.006
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.000	0.994	0.006
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.000	0.994	0.006
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.000	0.994	0.006
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.000	0.994	0.006
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.000	0.994	0.006
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.000	0.994	0.006
O60.3 Preterm delivery without spontaneous labour	0.000	0.994	0.006
O60.2 Preterm spontaneous labour with term delivery	0.000	0.994	0.006
O60.1 Preterm spontaneous labour with preterm delivery	0.000	0.994	0.006
O60.0 Preterm labour without delivery	0.000	0.994	0.006
E06.3 Autoimmune thyroiditis	0.000	0.994	0.006
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.000	0.994	0.006
K87.1 Disorders of pancreas in diseases classified elsewhere	0.000	0.994	0.006
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.000	0.994	0.006
O67.0 Intrapartum haemorrhage with coagulation defect	0.000	0.994	0.006
D68.1 Hereditary factor XI deficiency	0.000	0.994	0.006
Z80.9 Family history of malignant neoplasm, unspecified	0.006	0.994	0.000
D68.5 Primary Thrombophilia	0.000	0.994	0.006
O71.8 Other specified obstetric trauma	0.000	0.994	0.006
O61.1 Failed instrumental induction of labour	0.000	0.994	0.006
O64.8 Obstructed labour due to other malposition and malpresentation	0.000	0.994	0.005
O73.0 Retained placenta, without haemorrhage	0.000	0.994	0.006
I10-I15 Hypertensive diseases	0.000	0.994	0.006
K08.0 Exfoliation of teeth due to systemic causes	0.000	0.994	0.006
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.000	0.994	0.006
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.000	0.994	0.006
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.000	0.994	0.006
O65.2 Obstructed labour due to pelvic inlet contraction	0.000	0.994	0.006
O65.1 Obstructed labour due to generally contracted pelvis	0.000	0.994	0.006
O65.0 Obstructed labour due to deformed pelvis	0.000	0.994	0.006
M22.4 Chondromalacia patellae	0.000	0.994	0.006
O66 Other obstructed labour	0.000	0.994	0.006
O72.2 Delayed and secondary postpartum haemorrhage	0.000	0.994	0.006
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.000	0.994	0.006
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.000	0.994	0.005
D68.4 Acquired coagulation factor deficiency	0.000	0.994	0.005
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.994	0.006
O71.5 Other obstetric injury to pelvic organs	0.000	0.995	0.005
O71.3 Obstetric laceration of cervix	0.000	0.995	0.005
O71.2 Postpartum inversion of uterus	0.000	0.995	0.005
O71.1 Rupture of uterus during labour	0.000	0.995	0.005
O71.0 Rupture of uterus before onset of labour	0.000	0.995	0.005
Z99.1 Dependence on respirator	0.000	0.995	0.005
S22.21 Fracture of sternum (open)	0.005	0.995	0.000
K72.9 Hepatic failure, unspecified	0.000	0.995	0.005
O71.7 Obstetric haematoma of pelvis	0.000	0.995	0.005
O61.8 Other failed induction of labour	0.000	0.995	0.005
O71.4 Obstetric high vaginal laceration alone	0.000	0.995	0.005
D68.0 Von Willebrand's disease	0.000	0.995	0.005
I11 Hypertensive heart disease	0.000	0.995	0.005
O71.6 Obstetric damage to pelvic joints and ligaments	0.000	0.995	0.005
N22 Calculus of urinary tract in diseases classified elsewhere	0.005	0.995	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.000	0.995	0.005
O64.1 Obstructed labour due to breech presentation	0.000	0.995	0.005
K08.2 Atrophy of edentulous alveolar ridge	0.000	0.995	0.005
D68.2 Hereditary deficiency of other clotting factors	0.000	0.995	0.005
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.995	0.005
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.995	0.005
T93.2 Sequelae of other fractures of lower limb	0.005	0.995	0.000
O67.8 Other intrapartum haemorrhage	0.000	0.995	0.004
O66.0 Obstructed labour due to shoulder dystocia	0.000	0.995	0.005
H66.9 Otitis media, unspecified	0.005	0.995	0.000
O61.0 Failed medical induction of labour	0.000	0.995	0.004
O71.9 Obstetric trauma, unspecified	0.000	0.995	0.004
B34.9 Viral infection, unspecified	0.000	0.995	0.005
E11.9 Without complications	0.005	0.995	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.000	0.995	0.005
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.000	0.995	0.004
I13 Hypertensive heart and renal disease	0.000	0.996	0.004
N20.9 Urinary calculus, unspecified	0.004	0.996	0.000
O66.9 Obstructed labour, unspecified	0.000	0.996	0.004
O66.8 Other specified obstructed labour	0.000	0.996	0.004
O66.3 Obstructed labour due to other abnormalities of foetus	0.000	0.996	0.004
O66.1 Obstructed labour due to locked twins	0.000	0.996	0.004
E21.3 Hyperparathyroidism, unspecified	0.004	0.996	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.996	0.004
O61.9 Failed induction of labour, unspecified	0.000	0.996	0.004
N21 Calculus of lower urinary tract	0.004	0.996	0.000
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.004	0.996	0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.004	0.996	0.000
Z29.2 Other prophylactic chemotherapy	0.004	0.996	0.000
N72 Inflammatory disease of cervix uteri	0.000	0.996	0.004
O66.4 Failed trial of labour, unspecified	0.000	0.996	0.003
I15 Secondary hypertension	0.000	0.996	0.004
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.000	0.996	0.004
O66.2 Obstructed labour due to unusually large foetus	0.000	0.996	0.003
O72.1 Other immediate postpartum haemorrhage	0.000	0.996	0.004
N21.1 Calculus in urethra	0.003	0.996	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.003	0.996	0.000
Z34.8 Supervision of other normal pregnancy	0.004	0.996	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.997	0.003
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.997	0.003
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.997	0.003
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.997	0.003
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.003	0.997	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.003	0.997	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.997	0.003
U89.8 Agent resistant to other single specified antibiotic	0.003	0.997	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.003	0.997	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.003	0.997	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.001	0.997	0.003
S22.10 Multiple fractures of thoracic spine (closed)	0.003	0.997	0.000
S22.1 Multiple fractures of thoracic spine	0.003	0.997	0.000
N42.8 Other specified disorders of prostate	0.003	0.997	0.000
T93 Sequelae of injuries of lower limb	0.003	0.997	0.000
H34.8 Other retinal vascular occlusions	0.000	0.997	0.003
N21.8 Other lower urinary tract calculus	0.003	0.997	0.000
G82.2 Paraplegia, unspecified	0.000	0.997	0.003
I15.9 Seconday hypertension, unspecified	0.000	0.997	0.003
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.003	0.997	0.000
I15.8 Other secondary hypertension	0.000	0.997	0.003
I15.2 Hypertension secondary to endocrine disorders	0.000	0.997	0.003
M79.54 Residual foreign body in soft tissue (Hand)	0.003	0.997	0.000
I15.0 Renovascular hypertension	0.000	0.997	0.003
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.003	0.997	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.003	0.997	0.000
E13.9 Without complications	0.000	0.997	0.003
T98 Sequelae of other and unspecified effects of external causes	0.003	0.997	0.000
M19.1 Posttraumatic arthrosis of other joints	0.003	0.997	0.000
S22.0 Fracture of thoracic vertebra	0.003	0.997	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
H66 Suppurative and unspecified otitis media	0.003	0.997	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.003	0.997	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.003	0.997	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.003	0.997	0.000
E05.8 Other thyrotoxicosis	0.000	0.997	0.002
S22.9 Fracture of bony thorax, part unspecified	0.002	0.997	0.000
S22.8 Fracture of other parts of bony thorax	0.002	0.997	0.000
T93.1 Sequelae of fracture of femur	0.003	0.997	0.000
B24 Unspecified human immunodeficiency virus [HIV] disease	0.000	0.997	0.003
E05.5 Thyroid crisis or storm	0.001	0.997	0.002
E05.4 Thyrotoxicosis factitia	0.001	0.997	0.002
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.001	0.997	0.002
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.001	0.997	0.002
S22.11 Multiple fractures of thoracic spine (open)	0.002	0.997	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.002	0.998	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.002	0.998	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.002	0.998	0.000
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.002	0.998	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
H66.1 Chronic tubotympanic suppurative otitis media	0.002	0.998	0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue	0.000	0.998	0.002
M79.5 Residual foreign body in soft tissue	0.002	0.998	0.000
G82.1 Spastic paraplegia	0.000	0.998	0.002
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
M79.58 Residual foreign body in soft tissue (Other)	0.002	0.998	0.000
F01.9 Vascular dementia, unspecified	0.000	0.998	0.002
S22.5 Flail chest	0.002	0.998	0.000
T98.2 Sequelae of certain early complications of trauma	0.002	0.998	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.002	0.998	0.000
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.002	0.998	0.000
M19.18 Post-traumatic arthrosis of other joints (Other)	0.002	0.998	0.000
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.002	0.998	0.000
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.002	0.998	0.000
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.002	0.998	0.000
S22.01 Fracture of thoracic vertebra (open)	0.002	0.998	0.000
A08.4 Viral intestinal infection, unspecified	0.002	0.998	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.002	0.998	0.000
M79.56 Residual foreign body in soft tissue (Lower leg)	0.002	0.998	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.002	0.998	0.000
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.002	0.998	0.000
M79.57 Residual foreign body in soft tissue (Ankle and foot)	0.002	0.998	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.998	0.002
G56.2 Lesion of ulnar nerve	0.002	0.998	0.000
H90.5 Sensorineural hearing loss, unspecified	0.000	0.998	0.002
S22.81 Fracture of other parts of bony thorax (open)	0.002	0.998	0.000
S22.80 Fracture of other parts of bony thorax (closed)	0.002	0.998	0.000
S22.91 Fracture of bony thorax, part unspecified (open)	0.002	0.998	0.000
S22.90 Fracture of bony thorax, part unspecified (closed)	0.002	0.998	0.000
C97 Malignant neoplasms of independent (primary) multiple sites	0.002	0.998	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
S22.3 Fracture of rib	0.002	0.998	0.000
T93.0 Sequelae of open wound of lower limb	0.002	0.998	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.002	0.998	0.000
E73.9 Lactose intolerance, unspecified	0.000	0.998	0.002
H66.3 Other chronic suppurative otitis media	0.002	0.998	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.002	0.998	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
I42.8 Other cardiomyopathies	0.000	0.998	0.002
U89 Agent resistant to other and unspecified antibiotics	0.002	0.998	0.000
M79.53 Residual foreign body in soft tissue (Forearm)	0.002	0.998	0.000
H66.0 Acute suppurative otitis media	0.002	0.998	0.000
I15.1 Hypertension secondary to other renal disorders	0.000	0.998	0.002
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.002	0.998	0.000
D09.0 Bladder	0.002	0.998	0.000
H66.4 Suppurative otitis media, unspecified	0.002	0.998	0.000
G82 Paraplegia and tetraplegia	0.000	0.998	0.002
K72 Hepatic failure, not elsewhere classified	0.000	0.998	0.002
M79.59 Residual foreign body in soft tissue (Site unspecified)	0.002	0.998	0.000
M79.55 Residual foreign body in soft tissue (Pelvic region and thigh)	0.002	0.998	0.000
M79.52 Residual foreign body in soft tissue (Upper arm)	0.002	0.998	0.000
M79.51 Residual foreign body in soft tissue (Shoulder region)	0.002	0.998	0.000
M79.50 Residual foreign body in soft tissue (Multiple sites)	0.002	0.998	0.000
N20.1 Calculus of ureter	0.002	0.998	0.000
B34 Viral infection of unspecified site	0.000	0.998	0.002
L72.0 Epidermal cyst	0.000	0.998	0.002
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.000	0.998	0.002
T17.2 Foreign body in pharynx	0.000	0.998	0.002
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.002	0.998	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
S22.51 Flail chest (open)	0.002	0.998	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.001	0.998	0.001
T90.2 Sequelae of fracture of skull and facial bones	0.002	0.998	0.000
O70 Perineal laceration during delivery	0.000	0.998	0.002
E04 Other non-toxic goitre	0.001	0.998	0.001
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.998	0.002
N03.9 Unspecified	0.000	0.998	0.002
G56.1 Other lesions of median nerve	0.002	0.998	0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.000	0.998	0.002
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
B34.4 Papovirus infection, unspecified	0.000	0.998	0.002
K81 Cholecystitis	0.000	0.998	0.002
S22.31 Fracture of rib (open)	0.002	0.998	0.000
B35.3 Tinea pedis	0.000	0.998	0.002
U89.9 Agent resistant to unspecified antibiotic	0.002	0.998	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.998	0.002
K04.5 Chronic apical periodontitis	0.000	0.998	0.002
N18.2 Chronic kidney disease, stage 2	0.000	0.998	0.002
O42.9 Premature rupture of membranes, unspecified	0.000	0.998	0.002
Z03.1 Observation for suspected malignant neoplasm	0.002	0.998	0.000
B18.1 Chronic viral hepatitis B without delta-agent	0.002	0.998	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.998	0.002
E04.9 Non-toxic goitre, unspecified	0.002	0.998	0.000
G80.9 Infantile cerebral palsy, unspecified	0.000	0.998	0.002
G82.3 Flaccid tetraplegia	0.000	0.998	0.002
G82.0 Flaccid paraplegia	0.000	0.998	0.002
B34.3 Parvovirus infection, unspecified	0.000	0.998	0.001
B34.2 Coronavirus infection, unspecified	0.000	0.998	0.001
B34.0 Adenovirus infection, unspecified	0.000	0.998	0.001
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.002	0.998	0.000
E04.0 Non-toxic diffuse goitre	0.001	0.998	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.998	0.002
E21.2 Other hyperparathyroidism	0.002	0.998	0.000
F25.9 Schizoaffective disorder, unspecified	0.000	0.998	0.002
G11.9 Hereditary ataxia, unspecified	0.000	0.998	0.002
O70.3 Fourth degree perineal laceration during delivery	0.000	0.998	0.002
E04.8 Other specified non-toxic goitre	0.001	0.998	0.001
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.998	0.002
G80 Infantile cerebral palsy	0.000	0.998	0.002
S22.50 Flail chest (closed)	0.001	0.998	0.000
G56.3 Lesion of radial nerve	0.002	0.998	0.000
K72.1 Chronic hepatic failure	0.000	0.998	0.001
R45.8 Other symptoms and signs involving emotional state	0.000	0.998	0.002
F05.0 Delirium not superimposed on dementia, so described	0.000	0.998	0.002
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.001
S22.4 Multiple fractures of ribs	0.001	0.998	0.000
B34.1 Enterovirus infection, unspecified	0.000	0.998	0.001
G80.0 Spastic cerebral palsy	0.000	0.998	0.001
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.001	0.998	0.000
G80.1 Spastic diplegia	0.000	0.998	0.001
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.998	0.002
Z94.8 Other transplanted organ and tissue status	0.002	0.998	0.000
D67 Hereditary factor IX deficiency	0.000	0.998	0.001
G80.2 Infantile hemiplegia	0.000	0.998	0.001
O70.9 Perineal laceration during delivery, unspecified	0.000	0.998	0.001
L72 Follicular cysts of skin and subcutaneous tissue	0.000	0.998	0.002
K72.0 Acute and subacute hepatic failure	0.000	0.998	0.001
R50.8 Other specified fever	0.002	0.998	0.000
O42 Premature rupture of membranes	0.000	0.998	0.002
M91.20 Coxa plana-Mult sites	0.001	0.998	0.000
Z29 Need for other prophylactic measures	0.002	0.998	0.000
M13.09 Polyarthritis, unspecified (Site unspecified)	0.001	0.998	0.000
Y43.4 Immunosuppressive agents	0.001	0.998	0.000
F01 Vascular dementia	0.000	0.998	0.001
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.999	0.001
E21.5 Disorder of parathyroid gland, unspecified	0.001	0.999	0.000
G82.4 Spastic tetraplegia	0.000	0.999	0.001
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.999	0.001
X63.0 Home	0.000	0.999	0.001
G80.8 Other infantile cerebral palsy	0.000	0.999	0.001
R46.8 Other symptoms and signs involving appearance and behaviour	0.001	0.999	0.000
G80.4 Ataxic cerebral palsy	0.000	0.999	0.001
G80.3 Dyskinetic cerebral palsy	0.000	0.999	0.001
H90.2 Conductive hearing loss, unspecified	0.001	0.999	0.000
K81.8 Other cholecystitis	0.000	0.999	0.001
I12 Hypertensive renal disease	0.000	0.999	0.001
M13.00 Polyarthritis, unspecified (Multiple sites)	0.001	0.999	0.000
S22.41 Multiple fractures of ribs (open)	0.001	0.999	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.001	0.999	0.000
J93.9 Pneumothorax, unspecified	0.000	0.999	0.001
S46.2 Injury of muscle and tendon of other parts of biceps	0.001	0.999	0.000
E13 Other specified diabetes mellitus	0.000	0.999	0.001
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.999	0.001
G56.8 Other mononeuropathies of upper limb	0.001	0.999	0.000
J85.2 Abscess of lung without pneumonia	0.001	0.999	0.000
G56 Mononeuropathies of upper limb	0.001	0.999	0.000
R81 Glycosuria	0.000	0.999	0.001
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.001	0.999	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.001	0.999	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.000	0.999	0.001
B27.9 Infectious mononucleosis, unspecified	0.001	0.999	0.000
M92.7 Juvenile osteochondrosis of metatarsus	0.001	0.999	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.999	0.001
C82.4 Follicular lymphoma grade IIIb	0.001	0.999	0.000
H20.0 Acute and subacute iridocyclitis	0.000	0.999	0.001
N21.0 Calculus in bladder	0.001	0.999	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.001	0.999	0.000
S31.1 Open wound of abdominal wall	0.001	0.999	0.000
Z29.9 Prophylactic measure, unspecified	0.001	0.999	0.000
F01.8 Other vascular dementia	0.000	0.999	0.001
F01.3 Mixed cortical and subcortical vascular dementia	0.000	0.999	0.001
F01.2 Subcortical vascular dementia	0.000	0.999	0.001
F01.1 Multi-infarct dementia	0.000	0.999	0.001
F01.0 Vascular dementia of acute onset	0.000	0.999	0.001
B34.8 Other viral infections of unspecified site	0.000	0.999	0.001
C44.5 Skin of trunk	0.000	0.999	0.001
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.999	0.001
O70.2 Third degree perineal laceration during delivery	0.000	0.999	0.001
S46.1 Injury of muscle and tendon of long head of biceps	0.001	0.999	0.000
X45.0 Home	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations