TreeWAS – Variant ID: rs9472138

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.771	0.229
E03 Other hypothyroidism	0.000	0.834	0.166
E03.8 Other specified hypothyroidism	0.000	0.848	0.152
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.874	0.126
E03.5 Myxoedema coma	0.000	0.881	0.119
E03.4 Atrophy of thyroid (acquired)	0.000	0.881	0.119
E03.3 Postinfectious hypothyroidism	0.000	0.881	0.119
E03.1 Congenital hypothyroidism without goitre	0.000	0.881	0.119
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.886	0.114
I10 Essential (primary) hypertension	0.000	0.917	0.083
N70.9 Salpingitis and oophoritis, unspecified	0.000	0.928	0.072
N70 Salpingitis and oophoritis	0.000	0.931	0.069
N70.1 Chronic salpingitis and oophoritis	0.000	0.939	0.061
N70.0 Acute salpingitis and oophoritis	0.000	0.939	0.061
N75.1 Abscess of Bartholin's gland	0.000	0.941	0.059
N75 Diseases of Bartholin's gland	0.000	0.945	0.055
N70-N77 Inflammatory diseases of female pelvic organs	0.000	0.945	0.055
N76 Other inflammation of vagina and vulva	0.000	0.951	0.049
N71 Inflammatory disease of uterus, except cervix	0.000	0.955	0.045
N76.0 Acute vaginitis	0.000	0.955	0.045
N76.4 Abscess of vulva	0.000	0.957	0.043
N23 Unspecified renal colic	0.040	0.960	0.000
N75.9 Disease of Bartholin's gland, unspecified	0.000	0.960	0.040
N75.8 Other diseases of Bartholin's gland	0.000	0.960	0.040
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.000	0.961	0.039
N76.5 Ulceration of vagina	0.000	0.961	0.039
N76.1 Subacute and chronic vaginitis	0.000	0.962	0.038
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.000	0.963	0.037
N20.0 Calculus of kidney	0.037	0.963	0.000
N71.1 Chronic inflammatory disease of uterus	0.000	0.964	0.036
N20.2 Calculus of kidney with calculus of ureter	0.036	0.964	0.000
N20 Calculus of kidney and ureter	0.036	0.964	0.000
N76.8 Other specified inflammation of vagina and vulva	0.000	0.965	0.035
N20-N23 Urolithiasis	0.035	0.965	0.000
N71.0 Acute inflammatory disease of uterus	0.000	0.966	0.034
N71.9 Inflammatory disease of uterus, unspecified	0.000	0.967	0.033
N76.3 Subacute and chronic vulvitis	0.000	0.968	0.031
N76.6 Ulceration of vulva	0.000	0.969	0.031
N74.8 Female pelvic inflammatory disorders in other diseases classified elsewhere	0.000	0.971	0.028
N74.4 Female chlamydial pelvic inflammatory disease	0.000	0.971	0.028
N74.3 Female gonococcal pelvic inflammatory disease	0.000	0.971	0.028
N74.2 Female syphilitic pelvic inflammatory disease	0.000	0.971	0.028
N74.1 Female tuberculous pelvic inflammatory disease	0.000	0.971	0.028
N74.0 Tuberculous infection of cervix uteri	0.000	0.971	0.028
N77.8 Vulvovaginal ulceration and inflammation in other diseases classified elsewhere	0.000	0.973	0.026
N77.0 Ulceration of vulva in infectious and parasitic diseases classified elsewhere	0.000	0.973	0.026
N75.0 Cyst of Bartholin's gland	0.000	0.974	0.026
Z00.5 Examination of potential donor of organ and tissue	0.000	0.975	0.025
N22 Calculus of urinary tract in diseases classified elsewhere	0.025	0.975	0.000
N76.2 Acute vulvitis	0.000	0.975	0.025
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.000	0.975	0.025
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.976	0.024
Z00.4 General psychiatric examination, not elsewhere classified	0.000	0.976	0.024
N73 Other female pelvic inflammatory diseases	0.000	0.976	0.024
Z00.6 Examination for normal comparison and control in clinical research programme	0.000	0.976	0.024
N21 Calculus of lower urinary tract	0.023	0.977	0.000
I10-I15 Hypertensive diseases	0.000	0.977	0.023
M22.4 Chondromalacia patellae	0.000	0.978	0.022
I11 Hypertensive heart disease	0.000	0.980	0.020
N21.1 Calculus in urethra	0.020	0.980	0.000
N73.1 Chronic parametritis and pelvic cellulitis	0.000	0.981	0.019
N73.0 Acute parametritis and pelvic cellulitis	0.000	0.981	0.019
Z00.0 General medical examination	0.000	0.982	0.018
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.018	0.982	0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.018	0.982	0.000
Z00.8 Other general examinations	0.000	0.982	0.018
Z00.3 Examination for adolescent development state	0.000	0.982	0.018
Z00.2 Examination for period of rapid growth in childhood	0.000	0.982	0.018
Z00.1 Routine child health examination	0.000	0.982	0.018
J32.9 Chronic sinusitis, unspecified	0.000	0.982	0.018
N73.8 Other specified female pelvic inflammatory diseases	0.000	0.983	0.017
N73.4 Female chronic pelvic peritonitis	0.000	0.983	0.017
N73.3 Female acute pelvic peritonitis	0.000	0.983	0.017
N73.2 Unspecified parametritis and pelvic cellulitis	0.000	0.983	0.017
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.983	0.017
N21.9 Calculus of lower urinary tract, unspecified	0.017	0.983	0.000
N21.8 Other lower urinary tract calculus	0.016	0.983	0.000
I13 Hypertensive heart and renal disease	0.000	0.984	0.016
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.984	0.016
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.015	0.985	0.000
N73.5 Female pelvic peritonitis, unspecified	0.000	0.985	0.015
N20.9 Urinary calculus, unspecified	0.015	0.985	0.000
I15 Secondary hypertension	0.000	0.987	0.013
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.988	0.012
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.988	0.012
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.988	0.012
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.988	0.012
N73.9 Female pelvic inflammatory disease, unspecified	0.000	0.989	0.011
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.990	0.010
I15.8 Other secondary hypertension	0.000	0.991	0.009
I15.2 Hypertension secondary to endocrine disorders	0.000	0.991	0.009
I15.9 Seconday hypertension, unspecified	0.000	0.991	0.009
I15.0 Renovascular hypertension	0.000	0.991	0.009
N73.6 Female pelvic peritoneal adhesions	0.000	0.991	0.009
E00-E07 Disorders of thyroid gland	0.000	0.993	0.007
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.993	0.007
N21.0 Calculus in bladder	0.006	0.994	0.000
N20.1 Calculus of ureter	0.006	0.994	0.000
E07 Other disorders of thyroid	0.000	0.994	0.006
I15.1 Hypertension secondary to other renal disorders	0.000	0.994	0.006
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.994	0.006
E11.9 Without complications	0.006	0.994	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.994	0.006
D72.8 Other specified disorders of white blood cells	0.006	0.994	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.994	0.005
E00 Congenital iodine-deficiency syndrome	0.000	0.994	0.005
I12 Hypertensive renal disease	0.000	0.994	0.006
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
D68.9 Coagulation defect, unspecified	0.000	0.995	0.005
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
E07.8 Other specified disorders of thyroid	0.000	0.995	0.005
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.995	0.005
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.995	0.005
H34.8 Other retinal vascular occlusions	0.000	0.995	0.005
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
S22.20 Fracture of sternum (closed)	0.005	0.995	0.000
A08.4 Viral intestinal infection, unspecified	0.005	0.995	0.000
E06 Thyroiditis	0.000	0.995	0.005
E07.1 Dyshormogenetic goitre	0.000	0.995	0.004
E07.0 Hypersecretion of calcitonin	0.000	0.995	0.004
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.000	0.995	0.005
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.000	0.996	0.004
E07.9 Disorder of thyroid, unspecified	0.000	0.996	0.004
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.996	0.004
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.996	0.004
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.996	0.004
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.996	0.004
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.996	0.004
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.996	0.004
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.996	0.004
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.996	0.004
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O62 Abnormalities of forces of labour	0.000	0.996	0.004
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O62.3 Precipitate labour	0.000	0.996	0.004
D68 Other coagulation defects	0.000	0.996	0.004
Z99.1 Dependence on respirator	0.000	0.996	0.004
E06.9 Thyroiditis, unspecified	0.000	0.996	0.004
Z03.1 Observation for suspected malignant neoplasm	0.004	0.996	0.000
N72 Inflammatory disease of cervix uteri	0.000	0.996	0.004
O72.0 Third-stage haemorrhage	0.000	0.996	0.004
T93.2 Sequelae of other fractures of lower limb	0.004	0.996	0.000
E06.4 Drug-induced thyroiditis	0.000	0.996	0.003
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.996	0.003
E06.0 Acute thyroiditis	0.000	0.996	0.003
E21.3 Hyperparathyroidism, unspecified	0.004	0.996	0.000
D68.6 Other Thrombophilia	0.000	0.996	0.003
Z29.2 Other prophylactic chemotherapy	0.003	0.997	0.000
E06.5 Other chronic thyroiditis	0.000	0.997	0.003
O62.2 Other uterine inertia	0.000	0.997	0.003
O62.1 Secondary uterine inertia	0.000	0.997	0.003
D68.8 Other specified coagulation defects	0.000	0.997	0.003
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.997	0.003
K83.8 Other specified diseases of biliary tract	0.000	0.997	0.003
O69 Labour and delivery complicated by umbilical cord complications	0.000	0.997	0.003
D68.1 Hereditary factor XI deficiency	0.000	0.997	0.003
E06.1 Subacute thyroiditis	0.000	0.997	0.003
U89.8 Agent resistant to other single specified antibiotic	0.003	0.997	0.000
D68.5 Primary Thrombophilia	0.000	0.997	0.003
O62.9 Abnormality of forces of labour, unspecified	0.000	0.997	0.003
O62.8 Other abnormalities of forces of labour	0.000	0.997	0.003
D68.0 Von Willebrand's disease	0.000	0.997	0.003
O62.0 Primary inadequate contractions	0.000	0.997	0.003
B34.9 Viral infection, unspecified	0.000	0.997	0.003
K42.0 Umbilical hernia with obstruction, without gangrene	0.000	0.997	0.003
D68.4 Acquired coagulation factor deficiency	0.000	0.997	0.003
O75.8 Other specified complications of labour and delivery	0.000	0.997	0.003
O64 Obstructed labour due to malposition and malpresentation of foetus	0.000	0.997	0.003
O63.1 Prolonged second stage (of labour)	0.000	0.997	0.003
S22.2 Fracture of sternum	0.003	0.997	0.000
G82.2 Paraplegia, unspecified	0.000	0.997	0.003
N42.8 Other specified disorders of prostate	0.003	0.997	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.997	0.003
E06.3 Autoimmune thyroiditis	0.000	0.997	0.003
J93.9 Pneumothorax, unspecified	0.000	0.997	0.003
O75 Other complications of labour and delivery, not elsewhere classified	0.000	0.997	0.003
O60-O75 Complications of labour and delivery	0.000	0.997	0.003
O94-O99 Other obstetric conditions, not elsewhere classified	0.000	0.997	0.003
O69.5 Labour and delivery complicated by vascular lesion of cord	0.000	0.997	0.003
O69.4 Labour and delivery complicated by vasa praevia	0.000	0.997	0.003
O69.3 Labour and delivery complicated by short cord	0.000	0.997	0.003
O75.2 Pyrexia during labour, not elsewhere classified	0.000	0.997	0.003
O69.9 Labour and delivery complicated by cord complication, unspecified	0.000	0.997	0.003
O69.0 Labour and delivery complicated by prolapse of cord	0.000	0.997	0.003
O63 Long labour	0.000	0.997	0.003
O72 Postpartum haemorrhage	0.000	0.997	0.003
O75.0 Maternal distress during labour and delivery	0.000	0.998	0.002
K26.7 Chronic without haemorrhage or perforation	0.000	0.998	0.002
O69.8 Labour and delivery complicated by other cord complications	0.000	0.998	0.002
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.002	0.998	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.002	0.998	0.000
O64.5 Obstructed labour due to compound presentation	0.000	0.998	0.002
O64.4 Obstructed labour due to shoulder presentation	0.000	0.998	0.002
O64.3 Obstructed labour due to brow presentation	0.000	0.998	0.002
O64.2 Obstructed labour due to face presentation	0.000	0.998	0.002
H90.5 Sensorineural hearing loss, unspecified	0.000	0.998	0.002
K72.9 Hepatic failure, unspecified	0.000	0.998	0.002
T93 Sequelae of injuries of lower limb	0.002	0.998	0.000
S22.21 Fracture of sternum (open)	0.002	0.998	0.000
S51.0 Open wound of elbow	0.000	0.998	0.002
L72.8 Other follicular cysts of skin and subcutaneous tissue	0.000	0.998	0.002
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.002	0.998	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.002	0.998	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.000	0.998	0.002
M22 Disorders of patella	0.000	0.998	0.002
O42.9 Premature rupture of membranes, unspecified	0.000	0.998	0.002
O75.5 Delayed delivery after artificial rupture of membranes	0.000	0.998	0.002
O75.4 Other complications of obstetric surgery and procedures	0.000	0.998	0.002
O75.3 Other infection during labour	0.000	0.998	0.002
O75.1 Shock during or following labour and delivery	0.000	0.998	0.002
O60 Preterm delivery	0.000	0.998	0.002
H66.9 Otitis media, unspecified	0.002	0.998	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.002	0.998	0.000
O74 Complications of anaesthesia during labour and delivery	0.000	0.998	0.002
O97 Death from sequelae of direct obstetric causes	0.000	0.998	0.002
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.000	0.998	0.002
O95 Obstetric death of unspecified cause	0.000	0.998	0.002
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.000	0.998	0.002
J85.2 Abscess of lung without pneumonia	0.002	0.998	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.002	0.998	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.000	0.998	0.002
O63.2 Delayed delivery of second twin, triplet, etc.	0.000	0.998	0.002
K86.1 Other chronic pancreatitis	0.000	0.998	0.002
O72.3 Postpartum coagulation defects	0.000	0.998	0.002
R46.8 Other symptoms and signs involving appearance and behaviour	0.002	0.998	0.000
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.998	0.002
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.998	0.002
T98 Sequelae of other and unspecified effects of external causes	0.002	0.998	0.000
Z80.9 Family history of malignant neoplasm, unspecified	0.002	0.998	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.000	0.998	0.002
M54.36 Sciatica (Lumbar region)	0.000	0.998	0.002
C44.5 Skin of trunk	0.000	0.998	0.002
G82.1 Spastic paraplegia	0.000	0.998	0.002
O69.2 Labour and delivery complicated by other cord entanglement	0.000	0.998	0.002
T93.8 Sequelae of other specified injuries of lower limb	0.002	0.998	0.000
O63.9 Long labour, unspecified	0.000	0.998	0.002
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.000	0.998	0.002
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
G43.8 Other migraine	0.000	0.998	0.002
I12.9 Hypertensive renal disease without renal failure	0.000	0.998	0.002
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.998	0.002
U89 Agent resistant to other and unspecified antibiotics	0.002	0.998	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.002	0.998	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.002	0.998	0.000
O75.9 Complication of labour and delivery, unspecified	0.000	0.998	0.002
B27.9 Infectious mononucleosis, unspecified	0.002	0.998	0.000
E13.9 Without complications	0.000	0.998	0.002
D72 Other disorders of white blood cells	0.002	0.998	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.002	0.998	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.002	0.998	0.000
C97 Malignant neoplasms of independent (primary) multiple sites	0.002	0.998	0.000
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.002	0.998	0.000
O42 Premature rupture of membranes	0.000	0.998	0.002
O64.8 Obstructed labour due to other malposition and malpresentation	0.000	0.998	0.002
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.998	0.002
C90.2 Plasmacytoma, extramedullary	0.002	0.998	0.000
M22.1 Recurrent subluxation of patella	0.000	0.998	0.002
S12.9 Fracture of neck, part unspecified	0.002	0.998	0.000
O71 Other obstetric trauma	0.000	0.998	0.002
M22.0 Recurrent dislocation of patella	0.000	0.998	0.002
O60.3 Preterm delivery without spontaneous labour	0.000	0.998	0.002
O60.2 Preterm spontaneous labour with term delivery	0.000	0.998	0.002
O60.1 Preterm spontaneous labour with preterm delivery	0.000	0.998	0.002
O60.0 Preterm labour without delivery	0.000	0.998	0.002
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.000	0.998	0.002
O74.8 Other complications of anaesthesia during labour and delivery	0.000	0.998	0.002
O74.7 Failed or difficult intubation during labour and delivery	0.000	0.998	0.002
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.000	0.998	0.002
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.000	0.998	0.002
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.000	0.998	0.002
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.000	0.998	0.002
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.000	0.998	0.002
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.000	0.998	0.002
O96.9 Death from unspecified obstetric cause	0.000	0.998	0.002
O96.1 Death from indirect obstetric cause	0.000	0.998	0.002
O96.0 Death from direct obstetric cause	0.000	0.998	0.002
O97.9 Death from sequelae of obstetric cause, unspecified	0.000	0.998	0.002
O97.1 Death from sequelae of indirect obstetric cause	0.000	0.998	0.002
O97.0 Death from sequelae of direct obstetric cause	0.000	0.998	0.002
O61 Failed induction of labour	0.000	0.998	0.002
O73 Retained placenta and membranes, without haemorrhage	0.000	0.998	0.002
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.000	0.998	0.002
S22.1 Multiple fractures of thoracic spine	0.002	0.998	0.000
Z34.8 Supervision of other normal pregnancy	0.002	0.998	0.000
U89.9 Agent resistant to unspecified antibiotic	0.002	0.998	0.000
Z29 Need for other prophylactic measures	0.002	0.998	0.000
B34.4 Papovirus infection, unspecified	0.000	0.998	0.002
H81.0 Meniere's disease	0.000	0.998	0.002
S46.2 Injury of muscle and tendon of other parts of biceps	0.002	0.998	0.000
E88.2 Lipomatosis, not elsewhere classified	0.002	0.998	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.000	0.998	0.002
M91.20 Coxa plana-Mult sites	0.002	0.998	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.000	0.998	0.002
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.000	0.998	0.002
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.000	0.998	0.002
O65.2 Obstructed labour due to pelvic inlet contraction	0.000	0.998	0.002
O65.1 Obstructed labour due to generally contracted pelvis	0.000	0.998	0.002
O65.0 Obstructed labour due to deformed pelvis	0.000	0.998	0.002
T90.2 Sequelae of fracture of skull and facial bones	0.002	0.998	0.000
T93.1 Sequelae of fracture of femur	0.002	0.998	0.000
T98.2 Sequelae of certain early complications of trauma	0.002	0.998	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.002	0.998	0.000
H34 Retinal vascular occlusions	0.000	0.998	0.002
G80.9 Infantile cerebral palsy, unspecified	0.000	0.998	0.002
K63.1 Perforation of intestine (nontraumatic)	0.002	0.998	0.000
T93.0 Sequelae of open wound of lower limb	0.002	0.998	0.000
X63.0 Home	0.000	0.998	0.002
B34 Viral infection of unspecified site	0.000	0.998	0.002
M22.9 Disorder of patella, unspecified	0.000	0.998	0.002
O67.0 Intrapartum haemorrhage with coagulation defect	0.000	0.998	0.002
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.001
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.001
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.001
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.001
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.001
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.001
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.001
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.001
S46.0 Injury of tendon of the rotator cuff of shoulder	0.002	0.998	0.000
O61.1 Failed instrumental induction of labour	0.000	0.998	0.002
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.000	0.998	0.002
Z29.1 Prophylactic immunotherapy	0.002	0.998	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.998	0.002
D72.9 Disorder of white blood cells, unspecified	0.002	0.998	0.000
D72.0 Genetic anomalies of leukocytes	0.002	0.998	0.000
H81.2 Vestibular neuronitis	0.000	0.998	0.002
K86.3 Pseudocyst of pancreas	0.000	0.998	0.002
O71.8 Other specified obstetric trauma	0.000	0.998	0.002
S46.1 Injury of muscle and tendon of long head of biceps	0.002	0.998	0.000
G82 Paraplegia and tetraplegia	0.000	0.998	0.002
K85.1 Biliary acute pancreatitis	0.000	0.998	0.002
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.000	0.998	0.002
M79.58 Residual foreign body in soft tissue (Other)	0.002	0.998	0.000
M79.54 Residual foreign body in soft tissue (Hand)	0.002	0.998	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.998	0.002
M22.10 Recurrent subluxation of patella, unspecified knee	0.000	0.998	0.001
S12.91 Fracture of neck, part unspecified (open)	0.001	0.998	0.000
K85.9 Acute pancreatitis, unspecified	0.000	0.998	0.002
O71.6 Obstetric damage to pelvic joints and ligaments	0.000	0.998	0.001
O71.5 Other obstetric injury to pelvic organs	0.000	0.998	0.001
O71.3 Obstetric laceration of cervix	0.000	0.998	0.001
O71.2 Postpartum inversion of uterus	0.000	0.998	0.001
O71.1 Rupture of uterus during labour	0.000	0.998	0.001
O71.0 Rupture of uterus before onset of labour	0.000	0.998	0.001
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.001
O66 Other obstructed labour	0.000	0.998	0.002
M82.1 Osteoporosis in endocrine disorders	0.000	0.998	0.002
O63.0 Prolonged first stage (of labour)	0.000	0.998	0.002
O64.1 Obstructed labour due to breech presentation	0.000	0.998	0.001
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.000	0.998	0.001
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.001
K86 Other diseases of pancreas	0.000	0.998	0.002
M25.44 Effusion of joint (Hand)	0.000	0.998	0.002
H34.9 Retinal vascular occlusion, unspecified	0.000	0.998	0.002
O61.8 Other failed induction of labour	0.000	0.998	0.001
S46 Injury of muscle and tendon at shoulder and upper arm level	0.002	0.998	0.000
A08 Viral and other specified intestinal infections	0.002	0.998	0.000
K83 Other diseases of biliary tract	0.000	0.998	0.002
M79.57 Residual foreign body in soft tissue (Ankle and foot)	0.002	0.998	0.000
M79.56 Residual foreign body in soft tissue (Lower leg)	0.002	0.998	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.001	0.998	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.000	0.998	0.002
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.000	0.998	0.002
Z29.9 Prophylactic measure, unspecified	0.001	0.998	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.000	0.998	0.002
B18.1 Chronic viral hepatitis B without delta-agent	0.002	0.998	0.000
J85 Abscess of lung and mediastinum	0.002	0.998	0.000
M25.47 Effusion of joint (Ankle and foot)	0.000	0.998	0.002
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.998	0.002
H34.0 Transient retinal artery occlusion	0.000	0.998	0.001
M79.5 Residual foreign body in soft tissue	0.002	0.998	0.000
O71.4 Obstetric high vaginal laceration alone	0.000	0.998	0.001
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.001	0.998	0.000
S12.00 Fracture of first cervical vertebra (closed)	0.001	0.998	0.000
B34.3 Parvovirus infection, unspecified	0.000	0.998	0.001
B34.2 Coronavirus infection, unspecified	0.000	0.998	0.001
B34.1 Enterovirus infection, unspecified	0.000	0.998	0.001
B34.0 Adenovirus infection, unspecified	0.000	0.998	0.001
J85.1 Abscess of lung with pneumonia	0.001	0.998	0.000
K86.2 Cyst of pancreas	0.000	0.998	0.002
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.998	0.001
L57.0 Actinic keratosis	0.000	0.998	0.002
M19.1 Posttraumatic arthrosis of other joints	0.002	0.998	0.000
S12 Fracture of neck	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
M25.42 Effusion of joint (Upper arm)	0.000	0.998	0.001
O67.8 Other intrapartum haemorrhage	0.000	0.998	0.001
O71.7 Obstetric haematoma of pelvis	0.000	0.998	0.001
S12.2 Fracture of other specified cervical vertebra	0.001	0.998	0.000
S12.0 Fracture of first cervical vertebra	0.001	0.998	0.000
G80 Infantile cerebral palsy	0.000	0.998	0.002
S12.20 Fracture of other specified cervical vertebra (closed)	0.001	0.998	0.000
G30.9 Alzheimer's disease, unspecified	0.001	0.998	0.000
G80.2 Infantile hemiplegia	0.000	0.998	0.001
G80.1 Spastic diplegia	0.000	0.998	0.001
G82.3 Flaccid tetraplegia	0.000	0.998	0.001
G82.0 Flaccid paraplegia	0.000	0.998	0.001
I51.7 Cardiomegaly	0.000	0.998	0.002
R45.8 Other symptoms and signs involving emotional state	0.000	0.998	0.001
S14.1 Other and unspecified injuries of cervical spinal cord	0.001	0.998	0.000
S93.1 Dislocation of toe(s)	0.001	0.998	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.999	0.001
K83.9 Disease of biliary tract, unspecified	0.000	0.999	0.001
K86.9 Disease of pancreas, unspecified	0.000	0.999	0.001
O66.9 Obstructed labour, unspecified	0.000	0.999	0.001
O66.8 Other specified obstructed labour	0.000	0.999	0.001
O66.3 Obstructed labour due to other abnormalities of foetus	0.000	0.999	0.001
O66.1 Obstructed labour due to locked twins	0.000	0.999	0.001
O71.9 Obstetric trauma, unspecified	0.000	0.999	0.001
Q18.1 Preauricular sinus and cyst	0.001	0.999	0.000
S12.7 Multiple fractures of cervical spine	0.001	0.999	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.000	0.999	0.001
M82.18 Osteoporosis in endocrine disorders (Other)	0.000	0.999	0.001
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.000	0.999	0.001
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.000	0.999	0.001
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.000	0.999	0.001
M82.14 Osteoporosis in endocrine disorders (Hand)	0.000	0.999	0.001
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.000	0.999	0.001
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.000	0.999	0.001
G96.0 Cerebrospinal fluid leak	0.000	0.999	0.001
M22.3 Other derangements of patella	0.000	0.999	0.001
O66.0 Obstructed labour due to shoulder dystocia	0.000	0.999	0.001
S93.3 Dislocation of other and unspecified parts of foot	0.001	0.999	0.000
M79.53 Residual foreign body in soft tissue (Forearm)	0.001	0.999	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.001	0.999	0.000
A08.5 Other specified intestinal infections	0.001	0.999	0.000
A08.2 Adenoviral enteritis	0.001	0.999	0.000
A08.0 Rotaviral enteritis	0.001	0.999	0.000
H20.0 Acute and subacute iridocyclitis	0.000	0.999	0.001
J39.2 Other diseases of pharynx	0.001	0.999	0.000
K83.3 Fistula of bile duct	0.000	0.999	0.001
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.001	0.999	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.001	0.999	0.000
K85 Acute pancreatitis	0.000	0.999	0.001
M07.39 Other psoriatic arthropathies (Site unspecified)	0.001	0.999	0.000
M91.2 Coxa plana	0.001	0.999	0.000
O73.0 Retained placenta, without haemorrhage	0.000	0.999	0.001
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.999	0.001
Z29.8 Other specified prophylactic measures	0.001	0.999	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.000	0.999	0.001
G80.0 Spastic cerebral palsy	0.000	0.999	0.001
H81.3 Other peripheral vertigo	0.000	0.999	0.001
J85.3 Abscess of mediastinum	0.001	0.999	0.000
J85.0 Gangrene and necrosis of lung	0.001	0.999	0.000
K83.4 Spasm of sphincter of Oddi	0.000	0.999	0.001
K85.8 Other acute pancreatitis	0.000	0.999	0.001
O61.9 Failed induction of labour, unspecified	0.000	0.999	0.001
T93.9 Sequelae of unspecified injury of lower limb	0.001	0.999	0.000
Y43.4 Immunosuppressive agents	0.001	0.999	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.001	0.999	0.000
E88 Other metabolic disorders	0.001	0.999	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.001	0.999	0.000
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.001	0.999	0.000
M19.18 Post-traumatic arthrosis of other joints (Other)	0.001	0.999	0.000
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.001	0.999	0.000
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.001	0.999	0.000
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.001	0.999	0.000
M79.59 Residual foreign body in soft tissue (Site unspecified)	0.001	0.999	0.000
M79.55 Residual foreign body in soft tissue (Pelvic region and thigh)	0.001	0.999	0.000
M79.52 Residual foreign body in soft tissue (Upper arm)	0.001	0.999	0.000
M79.51 Residual foreign body in soft tissue (Shoulder region)	0.001	0.999	0.000
M79.50 Residual foreign body in soft tissue (Multiple sites)	0.001	0.999	0.000
G11.9 Hereditary ataxia, unspecified	0.000	0.999	0.001
K62.0 Anal polyp	0.001	0.999	0.000
K83.5 Biliary cyst	0.000	0.999	0.001
S12.8 Fracture of other parts of neck	0.001	0.999	0.000
S93.4 Sprain and strain of ankle	0.001	0.999	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.001	0.999	0.000
S93.5 Sprain and strain of toe(s)	0.001	0.999	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.001	0.999	0.000
S12.01 Fracture of first cervical vertebra (open)	0.001	0.999	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.001	0.999	0.000
C90.1 Plasma cell leukaemia	0.001	0.999	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.001	0.999	0.000
G80.4 Ataxic cerebral palsy	0.000	0.999	0.001
G80.3 Dyskinetic cerebral palsy	0.000	0.999	0.001
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.999	0.001
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.001	0.999	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.001	0.999	0.000
G80.8 Other infantile cerebral palsy	0.000	0.999	0.001
O61.0 Failed medical induction of labour	0.000	0.999	0.001
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.000	0.999	0.001
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.001	0.999	0.000
S12.71 Multiple fractures of cervical spine (open)	0.001	0.999	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.001	0.999	0.000
C90.0 Multiple myeloma	0.001	0.999	0.000
S46.3 Injury of muscle and tendon of triceps	0.001	0.999	0.000
H33.4 Traction detachment of retina	0.000	0.999	0.001
H34.1 Central retinal artery occlusion	0.000	0.999	0.001
H35.3 Degeneration of macula and posterior pole	0.000	0.999	0.001
K83.2 Perforation of bile duct	0.000	0.999	0.001
K85.3 Drug-induced acute pancreatitis	0.000	0.999	0.001
K85.0 Idiopathic acute pancreatitis	0.000	0.999	0.001
O66.2 Obstructed labour due to unusually large foetus	0.000	0.999	0.001
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.999	0.001
M91.29 Coxa plana-Site unspec	0.001	0.999	0.000
M91.28 Coxa plana-Other	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations