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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9501161
log Bayes Factor = 6.70501
Chromosome 6   position 31,924,327  (GRCh37) Explore rs9501161 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10 Insulin-dependent diabetes mellitus
0.000 0.001 0.999
E10.9 Without complications
0.000 0.002 0.998
K90.0 Coeliac disease
0.000 0.003 0.997
E10-E14 Diabetes mellitus
0.000 0.005 0.995
E14 Unspecified diabetes mellitus
0.000 0.020 0.980
E10.3 With ophthalmic complications
0.000 0.040 0.960
E14.9 Without complications
0.000 0.041 0.959
M20.1 Hallux valgus (acquired)
0.949 0.051 0.000
E10.1 With ketoacidosis
0.000 0.053 0.947
M20.5 Other deformities of toe(s) (acquired)
0.947 0.053 0.000
M20 Acquired deformities of fingers and toes
0.946 0.054 0.000
E10.5 With peripheral circulatory complications
0.000 0.101 0.899
E11 Non-insulin-dependent diabetes mellitus
0.000 0.109 0.891
M20.2 Hallux rigidus
0.880 0.120 0.000
E14.3 With ophthalmic complications
0.000 0.122 0.878
K90 Intestinal malabsorption
0.000 0.130 0.870
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.139 0.861
E10.2 With renal complications
0.000 0.169 0.831
E11.5 With peripheral circulatory complications
0.000 0.193 0.807
K90-K93 Other diseases of the digestive system
0.000 0.197 0.803
H53-H54 Visual disturbances and blindness
0.000 0.201 0.799
H53 Visual disturbances
0.000 0.204 0.796
Chapter VIII Diseases of the ear and mastoid process
0.000 0.210 0.790
H65-H75 Diseases of middle ear and mastoid
0.000 0.211 0.789
Chapter VII Diseases of the eye and adnexa
0.000 0.213 0.787
H53.8 Other visual disturbances
0.000 0.216 0.784
# Top node
0.000 0.218 0.782
Chapter XI Diseases of the digestive system
0.000 0.219 0.781
E10.4 With neurological complications
0.000 0.224 0.776
K70-K77 Diseases of liver
0.000 0.226 0.774
H54 Blindness and low vision
0.000 0.228 0.772
E11.2 With renal complications
0.000 0.232 0.768
E00-E07 Disorders of thyroid gland
0.000 0.233 0.767
K70 Alcoholic liver disease
0.000 0.233 0.767
H90-H95 Other disorders of ear
0.000 0.235 0.765
M20.6 Acquired deformity of toe(s), unspecified
0.755 0.245 0.000
H90 Conductive and sensorineural hearing loss
0.000 0.248 0.752
Chapter IX Diseases of the circulatory system
0.000 0.249 0.751
H30-H36 Disorders of choroid and retina
0.000 0.251 0.749
K72 Hepatic failure, not elsewhere classified
0.000 0.255 0.745
H53.1 Subjective visual disturbances
0.000 0.257 0.743
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.257 0.743
H72 Perforation of tympanic membrane
0.000 0.259 0.741
E11.1 With ketoacidosis
0.000 0.261 0.739
K70.3 Alcoholic cirrhosis of liver
0.000 0.261 0.739
H74 Other disorders of middle ear and mastoid
0.000 0.268 0.732
I60-I69 Cerebrovascular diseases
0.000 0.270 0.730
K70.9 Alcoholic liver disease, unspecified
0.000 0.271 0.729
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.272 0.728
K50-K52 Noninfective enteritis and colitis
0.000 0.273 0.727
I63 Cerebral infarction
0.000 0.274 0.726
I73 Other peripheral vascular diseases
0.000 0.275 0.725
I05-I09 Chronic rheumatic heart diseases
0.000 0.278 0.722
I63.9 Cerebral infarction, unspecified
0.000 0.279 0.721
H54.7 Unspecified visual loss
0.000 0.280 0.720
H36 Retinal disorders in diseases classified elsewhere
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.284 0.716
E10.7 With multiple complications
0.000 0.284 0.716
E10.0 With coma
0.000 0.284 0.716
H66 Suppurative and unspecified otitis media
0.000 0.285 0.715
K51 Ulcerative colitis
0.000 0.286 0.714
I08 Multiple valve diseases
0.000 0.286 0.714
E12 Malnutrition-related diabetes mellitus
0.000 0.287 0.713
K51.9 Ulcerative colitis, unspecified
0.000 0.291 0.709
H53.0 Amblyopia ex anopsia
0.000 0.294 0.706
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.294 0.706
H73 Other disorders of tympanic membrane
0.000 0.295 0.705
H72.0 Central perforation of tympanic membrane
0.000 0.296 0.704
H90.5 Sensorineural hearing loss, unspecified
0.000 0.297 0.703
E14.8 With unspecified complications
0.000 0.297 0.703
E14.7 With multiple complications
0.000 0.297 0.703
E14.6 With other specified complications
0.000 0.297 0.703
E14.5 With peripheral circulatory complications
0.000 0.297 0.703
E14.2 Withrenal complications
0.000 0.297 0.703
E14.1 With ketoacidosis
0.000 0.297 0.703
E14.0 With coma
0.000 0.297 0.703
E11.4 With neurological complications
0.000 0.298 0.702
K72.9 Hepatic failure, unspecified
0.000 0.302 0.698
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.302 0.697
H36.0 Diabetic retinopathy
0.000 0.305 0.695
E11.3 With ophthalmic complications
0.000 0.305 0.695
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.311 0.689
E10.6 With other specified complications
0.000 0.313 0.687
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.316 0.684
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.316 0.684
I73.0 Raynaud's syndrome
0.000 0.318 0.682
H71 Cholesteatoma of middle ear
0.000 0.319 0.681
H90.3 Sensorineural hearing loss, bilateral
0.000 0.320 0.680
E11.8 With unspecified complications
0.000 0.324 0.676
H35 Other retinal disorders
0.000 0.324 0.676
H54.9 Unspecified visual impairment (binocular)
0.000 0.330 0.670
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.332 0.668
H35.8 Other specified retinal disorders
0.000 0.335 0.665
E50-E64 Other nutritional deficiencies
0.000 0.335 0.665
I73.9 Peripheral vascular disease, unspecified
0.000 0.338 0.662
H74.4 Polyp of middle ear
0.000 0.339 0.661
I71 Aortic aneurysm and dissection
0.000 0.340 0.660
K72.0 Acute and subacute hepatic failure
0.000 0.347 0.653
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.348 0.652
H66.3 Other chronic suppurative otitis media
0.000 0.352 0.648
H73.8 Other specified disorders of tympanic membrane
0.000 0.354 0.646
E11.7 With multiple complications
0.000 0.361 0.639
H90.2 Conductive hearing loss, unspecified
0.000 0.362 0.638
E13 Other specified diabetes mellitus
0.000 0.363 0.636
E06 Thyroiditis
0.000 0.366 0.634
I08.0 Disorders of both mitral and aortic valves
0.000 0.367 0.633
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.373 0.627
K90.8 Other intestinal malabsorption
0.000 0.376 0.623
K90.3 Pancreatic steatorrhoea
0.000 0.376 0.623
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.376 0.623
K90.1 Tropical sprue
0.000 0.376 0.623
M20.0 Deformity of finger(s)
0.622 0.377 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.379 0.621
K70.0 Alcoholic fatty liver
0.000 0.380 0.620
I77 Other disorders of arteries and arterioles
0.000 0.383 0.617
I67 Other cerebrovascular diseases
0.000 0.384 0.616
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.384 0.616
E14.4 With neurological complications
0.000 0.386 0.614
H35.0 Background retinopathy and retinal vascular changes
0.000 0.387 0.613
H74.0 Tympanosclerosis
0.000 0.394 0.606
E11.6 With other specified complications
0.000 0.402 0.598
H72.9 Perforation of tympanic membrane, unspecified
0.000 0.405 0.595
H92 Otalgia and effusion of ear
0.000 0.406 0.594
N81.4 Uterovaginal prolapse, unspecified
0.592 0.408 0.000
H54.0 Blindness, both eyes
0.000 0.412 0.588
N81 Female genital prolapse
0.587 0.413 0.000
E40-E46 Malnutrition
0.000 0.413 0.587
H46 Optic neuritis
0.000 0.413 0.587
Chapter XXII Codes for special purposes
0.000 0.413 0.587
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.414 0.586
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.416 0.584
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.000 0.418 0.582
E16 Other disorders of pancreatic internal secretion
0.000 0.419 0.581
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.424 0.576
I69 Sequelae of cerebrovascular disease
0.000 0.428 0.572
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.428 0.572
K73 Chronic hepatitis, not elsewhere classified
0.000 0.429 0.571
H53.6 Night blindness
0.000 0.429 0.571
H53.5 Colour vision deficiencies
0.000 0.429 0.571
H53.3 Other disorders of binocular vision
0.000 0.429 0.571
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.429 0.571
H34 Retinal vascular occlusions
0.000 0.430 0.570
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.434 0.566
H70 Mastoiditis and related conditions
0.000 0.434 0.566
H68 Eustachian salpingitis and obstruction
0.000 0.434 0.566
H67 Otitis media in diseases classified elsewhere
0.000 0.434 0.566
H04 Disorders of lachrymal system
0.000 0.437 0.563
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.000 0.437 0.563
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.437 0.562
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.440 0.560
H02 Other disorders of eyelid
0.000 0.440 0.560
H54.4 Blindness, one eye
0.000 0.442 0.558
H66.9 Otitis media, unspecified
0.000 0.444 0.556
K77 Liver disorders in diseases classified elsewhere
0.000 0.445 0.555
K71 Toxic liver disease
0.000 0.445 0.555
I67.8 Other specified cerebrovascular diseases
0.000 0.446 0.554
H54.6 Unqualified visual loss, one eye
0.000 0.447 0.553
H54.5 Low vision, one eye
0.000 0.447 0.553
H54.3 Unqualified visual loss, both eyes
0.000 0.447 0.553
H54.2 Low vision, both eyes
0.000 0.447 0.553
H54.1 Blindness, one eye, low vision, other eye
0.000 0.447 0.553
N81.6 Rectocele
0.553 0.447 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.450 0.550
E00 Congenital iodine-deficiency syndrome
0.000 0.450 0.550
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.450 0.550
K70.4 Alcoholic hepatic failure
0.000 0.450 0.550
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.450 0.550
H94 Other disorders of ear in diseases classified elsewhere
0.000 0.451 0.549
H02.9 Disorder of eyelid, unspecified
0.000 0.453 0.547
H53.2 Diplopia
0.000 0.455 0.545
H74.3 Other acquired abnormalities of ear ossicles
0.000 0.455 0.545
I77.6 Arteritis, unspecified
0.000 0.456 0.544
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.456 0.544
N81.2 Incomplete uterovaginal prolapse
0.540 0.460 0.000
H10-H13 Disorders of conjunctiva
0.000 0.460 0.540
H93 Other disorders of ear, not elsewhere classified
0.000 0.460 0.539
K75 Other inflammatory liver diseases
0.000 0.461 0.539
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.461 0.539
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.461 0.539
H90.0 Conductive hearing loss, bilateral
0.000 0.461 0.539
I00-I02 Acute rheumatic fever
0.000 0.461 0.539
H47 Other disorders of optic [2nd] nerve and visual pathways
0.000 0.463 0.537
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.463 0.537
H30 Chorioretinal inflammation
0.000 0.463 0.537
N81.8 Other female genital prolapse
0.535 0.465 0.000
K72.1 Chronic hepatic failure
0.000 0.465 0.534
H31 Other disorders of choroid
0.000 0.466 0.533
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.468 0.532
H72.2 Other marginal perforations of tympanic membrane
0.000 0.468 0.532
H72.1 Attic perforation of tympanic membrane
0.000 0.468 0.532
I70 Atherosclerosis
0.000 0.468 0.532
I10-I15 Hypertensive diseases
0.000 0.472 0.528
I71.0 Dissection of aorta [any part]
0.000 0.473 0.527
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.000 0.474 0.526
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.474 0.526
H35.7 Separation of retinal layers
0.000 0.475 0.525
H74.9 Disorder of middle ear and mastoid, unspecified
0.000 0.475 0.525
H74.2 Discontinuity and dislocation of ear ossicles
0.000 0.475 0.525
H74.1 Adhesive middle ear disease
0.000 0.475 0.525
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.476 0.523
E05.5 Thyroid crisis or storm
0.000 0.478 0.522
E05.4 Thyrotoxicosis factitia
0.000 0.478 0.522
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.478 0.522
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.478 0.522
H80-H83 Diseases of inner ear
0.000 0.479 0.521
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.479 0.521
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.479 0.521
I73.8 Other specified peripheral vascular diseases
0.000 0.480 0.520
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.480 0.520
E06.3 Autoimmune thyroiditis
0.000 0.481 0.519
I09 Other rheumatic heart diseases
0.000 0.482 0.517
I06 Rheumatic aortic valve diseases
0.000 0.482 0.517
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.483 0.517
N81.9 Female genital prolapse, unspecified
0.516 0.484 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.484 0.516
H74.8 Other specified disorders of middle ear and mastoid
0.000 0.484 0.516
E04 Other non-toxic goitre
0.000 0.484 0.516
E70-E90 Metabolic disorders
0.000 0.485 0.515
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.485 0.514
I08.8 Other multiple valve diseases
0.000 0.486 0.513
H66.4 Suppurative otitis media, unspecified
0.000 0.487 0.513
H66.2 Chronic atticoantral suppurative otitis media
0.000 0.487 0.513
H66.1 Chronic tubotympanic suppurative otitis media
0.000 0.487 0.513
H66.0 Acute suppurative otitis media
0.000 0.487 0.513
K35-K38 Diseases of appendix
0.000 0.487 0.513
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.488 0.512
E12.9 Without complications
0.000 0.488 0.511
E12.8 With unspecified complications
0.000 0.488 0.511
E12.7 With multiple complications
0.000 0.488 0.511
E12.6 With other specified complications
0.000 0.488 0.511
E12.5 With peripheral circulatory complications
0.000 0.488 0.511
E12.4 With neurological complications
0.000 0.488 0.511
E12.3 With ophthalmic complications
0.000 0.488 0.511
E12.2 With renal complications
0.000 0.488 0.511
E12.1 With ketoacidosis
0.000 0.488 0.511
E12.0 With coma
0.000 0.488 0.511
I62 Other nontraumatic intracranial haemorrhage
0.000 0.489 0.511
I72 Other aneurysm
0.000 0.490 0.509
H05 Disorders of orbit
0.000 0.491 0.509
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.491 0.508
I77.1 Stricture of artery
0.000 0.493 0.507
H73.9 Disorder of tympanic membrane, unspecified
0.000 0.494 0.506
H73.1 Chronic myringitis
0.000 0.494 0.506
H73.0 Acute myringitis
0.000 0.494 0.506
H06.2 Dysthyroid exophthalmos
0.000 0.495 0.505
N81.5 Vaginal enterocele
0.504 0.496 0.000
M20.3 Other deformity of hallux (acquired)
0.503 0.497 0.000
I69.3 Sequelae of cerebral infarction
0.000 0.497 0.503
E53 Deficiency of other B group vitamins
0.000 0.497 0.503
E15 Nondiabetic hypoglycaemic coma
0.000 0.500 0.500
H92.1 Otorrhoea
0.000 0.500 0.499
E61 Deficiency of other nutrient elements
0.000 0.503 0.497
H03 Disorders of eyelid in diseases classified elsewhere
0.000 0.506 0.494
K51.5 Mucosal proctocolitis
0.000 0.507 0.493
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.508 0.492
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.508 0.492
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.000 0.509 0.490
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.510 0.490
H53.9 Visual disturbance, unspecified
0.000 0.510 0.489
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.000 0.512 0.488
H35.2 Other proliferative retinopathy
0.000 0.515 0.484
H35.1 Retinopathy of prematurity
0.000 0.515 0.484
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.516 0.484
H34.8 Other retinal vascular occlusions
0.000 0.516 0.484
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.517 0.483
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.000 0.517 0.483
E06.9 Thyroiditis, unspecified
0.000 0.517 0.483
E55 Vitamin D deficiency
0.000 0.518 0.482
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.000 0.520 0.480
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.521 0.479
K51.8 Other ulcerative colitis
0.000 0.521 0.478
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.522 0.478
E65-E68 Obesity and other hyperalimentation
0.000 0.523 0.477
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.523 0.476
E63 Other nutritional deficiencies
0.000 0.523 0.476
E56 Other vitamin deficiencies
0.000 0.523 0.476
E51 Thiamine deficiency
0.000 0.523 0.476
E50 Vitamin A deficiency
0.000 0.523 0.476
E60 Dietary zinc deficiency
0.000 0.523 0.476
E59 Dietary selenium deficiency
0.000 0.523 0.476
E58 Dietary calcium deficiency
0.000 0.523 0.476
E54 Ascorbic acid deficiency
0.000 0.523 0.476
E52 Niacin deficiency [pellagra]
0.000 0.523 0.476
H02.6 Xanthelasma of eyelid
0.000 0.525 0.475
I77.8 Other specified disorders of arteries and arterioles
0.000 0.526 0.474
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.527 0.473
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.527 0.473
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.527 0.473
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.527 0.473
H04.2 Epiphora
0.000 0.527 0.473
K51.4 Pseudopolyposis of colon
0.000 0.527 0.473
E83 Disorders of mineral metabolism
0.000 0.527 0.473
E11.0 With coma
0.000 0.528 0.472
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.528 0.472
K52 Other non-infective gastro-enteritis and colitis
0.000 0.528 0.472
I67.9 Cerebrovascular disease, unspecified
0.000 0.529 0.471
H72.8 Other perforations of tympanic membrane
0.000 0.531 0.469
K51.2 Ulcerative (chronic) proctitis
0.000 0.532 0.468
H47.3 Other disorders of optic disk
0.000 0.534 0.466
H69 Other disorders of Eustachian tube
0.000 0.535 0.464
H02.5 Other disorders affecting eyelid function
0.000 0.536 0.464
I67.2 Cerebral atherosclerosis
0.000 0.540 0.460
K91.4 Colostomy and enterostomy malfunction
0.000 0.541 0.459
H04.1 Other disorders of lachrymal gland
0.000 0.542 0.458
K90.9 Intestinal malabsorption, unspecified
0.000 0.542 0.457
I63.8 Other cerebral infarction
0.000 0.543 0.457
I74 Arterial embolism and thrombosis
0.000 0.543 0.457
E13.8 With unspecified complications
0.000 0.543 0.456
E13.7 With multiple complications
0.000 0.543 0.456
E13.6 With other specified complications
0.000 0.543 0.456
E13.5 With peripheral circulatory complications
0.000 0.543 0.456
E13.4 With neurological complications
0.000 0.543 0.456
E13.3 With ophthalmic complications
0.000 0.543 0.456
E13.2 With renal complications
0.000 0.543 0.456
E13.1 With ketoacidosis
0.000 0.543 0.456
E13.0 With coma
0.000 0.543 0.456
E06.5 Other chronic thyroiditis
0.000 0.546 0.454
E06.4 Drug-induced thyroiditis
0.000 0.546 0.454
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.546 0.454
E06.1 Subacute thyroiditis
0.000 0.546 0.454
E06.0 Acute thyroiditis
0.000 0.546 0.454
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.548 0.452
H04.3 Acute and unspecified inflammation of lachrymal passages
0.000 0.549 0.451
I72.3 Aneurysm of iliac artery
0.000 0.549 0.451
K75.4 Autoimmune hepatitis
0.000 0.550 0.450
H00 Hordeolum and chalazion
0.000 0.552 0.448
I12 Hypertensive renal disease
0.000 0.553 0.447
H83 Other diseases of inner ear
0.000 0.555 0.445
H60-H62 Diseases of external ear
0.000 0.556 0.444
H11 Other disorders of conjunctiva
0.000 0.556 0.444
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.556 0.444
E05.8 Other thyrotoxicosis
0.000 0.557 0.443
I77.5 Necrosis of artery
0.000 0.557 0.443
I77.4 Coeliac artery compression syndrome
0.000 0.557 0.443
I77.3 Arterial fibromuscular dysplasia
0.000 0.557 0.443
I77.2 Rupture of artery
0.000 0.557 0.443
E83.1 Disorders of iron metabolism
0.000 0.557 0.443
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.558 0.442
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.558 0.442
I67.5 Moyamoya disease
0.000 0.558 0.442
I67.4 Hypertensive encephalopathy
0.000 0.558 0.442
I67.3 Progressive vascular leukoencephalopathy
0.000 0.558 0.442
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.558 0.442
I79.1 Aortitis in diseases classified elsewhere
0.000 0.558 0.442
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.558 0.442
H53.4 Visual field defects
0.000 0.558 0.441
K73.9 Chronic hepatitis, unspecified
0.000 0.559 0.441
I70.0 Atherosclerosis of aorta
0.000 0.561 0.439
H35.6 Retinal haemorrhage
0.000 0.562 0.437
E07 Other disorders of thyroid
0.000 0.564 0.436
L20-L30 Dermatitis and eczema
0.000 0.564 0.436
H04.4 Chronic inflammation of lachrymal passages
0.000 0.567 0.432
E03 Other hypothyroidism
0.000 0.568 0.432
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.569 0.431
H92.2 Otorrhagia
0.000 0.574 0.426
I07 Rheumatic tricuspid valve diseases
0.000 0.575 0.425
I08.9 Multiple valve disease, unspecified
0.000 0.575 0.425
H35.4 Peripheral retinal degeneration
0.000 0.576 0.424
H01 Other inflammation of eyelid
0.000 0.576 0.424
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.577 0.423
L30 Other dermatitis
0.000 0.579 0.421
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.579 0.421
E45 Retarded development following protein-energy malnutrition
0.000 0.579 0.421
E43 Unspecified severe protein-energy malnutrition
0.000 0.579 0.421
E42 Marasmic kwashiorkor
0.000 0.579 0.421
E41 Nutritional marasmus
0.000 0.579 0.421
E40 Kwashiorkor
0.000 0.579 0.421
I61 Intracerebral haemorrhage
0.000 0.580 0.419
H55-H59 Other disorders of eye and adnexa
0.000 0.581 0.419
H93.1 Tinnitus
0.000 0.582 0.418
E85 Amyloidosis
0.000 0.582 0.418
H95.1 Other disorders following mastoidectomy
0.000 0.583 0.417
H06.3 Other disorders of orbit in diseases classified elsewhere
0.000 0.583 0.417
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.000 0.583 0.417
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.000 0.583 0.417
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.583 0.416
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.583 0.416
E16.4 Abnormal secretion of gastrin
0.000 0.583 0.416
E16.3 Increased secretion of glucagon
0.000 0.583 0.416
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.583 0.416
K37 Unspecified appendicitis
0.000 0.585 0.415
N81.3 Complete uterovaginal prolapse
0.414 0.586 0.000
H91 Other hearing loss
0.000 0.586 0.414
K38 Other diseases of appendix
0.000 0.587 0.413
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.587 0.413
K93.1 Megacolon in Chagas' disease
0.000 0.587 0.413
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.587 0.413
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.589 0.410
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.590 0.409
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.590 0.409
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.590 0.409
H34.9 Retinal vascular occlusion, unspecified
0.000 0.591 0.409
H34.1 Central retinal artery occlusion
0.000 0.591 0.409
H34.0 Transient retinal artery occlusion
0.000 0.591 0.409
H49 Paralytic strabismus
0.000 0.591 0.409
E53.8 Deficiency of other specified B group vitamins
0.000 0.591 0.409
K91.3 Postoperative intestinal obstruction
0.000 0.592 0.408
K70.1 Alcoholic hepatitis
0.000 0.592 0.408
L30.9 Dermatitis, unspecified
0.000 0.593 0.407
H11.3 Conjunctival haemorrhage
0.000 0.593 0.407
H67.8 Otitis media in other diseases classified elsewhere
0.000 0.594 0.406
H67.1 Otitis media in viral diseases classified elsewhere
0.000 0.594 0.406
H67.0 Otitis media in bacterial diseases classified elsewhere
0.000 0.594 0.406
H68.1 Obstruction of Eustachian tube
0.000 0.594 0.406
H68.0 Eustachian salpingitis
0.000 0.594 0.406
H70.9 Mastoiditis, unspecified
0.000 0.594 0.406
H70.8 Other mastoiditis and related conditions
0.000 0.594 0.406
H70.2 Petrositis
0.000 0.594 0.406
H70.1 Chronic mastoiditis
0.000 0.594 0.406
H70.0 Acute mastoiditis
0.000 0.594 0.406
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.594 0.406
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere
0.000 0.594 0.406
H04.9 Disorder of lachrymal system, unspecified
0.000 0.596 0.404
H04.6 Other changes in lachrymal passages
0.000 0.596 0.404
H04.0 Dacryoadenitis
0.000 0.596 0.404
H95.9 Postprocedural disorder of ear and mastoid process, unspecified
0.000 0.596 0.403
H95.8 Other postprocedural disorders of ear and mastoid process
0.000 0.596 0.403
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity
0.000 0.596 0.403
I15 Secondary hypertension
0.000 0.598 0.402
P90-P96 Other disorders originating in the perinatal period
0.000 0.598 0.402
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.000 0.598 0.402
P75-P78 Digestive system disorders of fetus and newborn
0.000 0.598 0.402
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.000 0.598 0.402
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.000 0.598 0.402
P35-P39 Infections specific to the perinatal period
0.000 0.598 0.402
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.000 0.598 0.402
P10-P15 Birth trauma
0.000 0.598 0.402
P05-P08 Disorders related to length of gestation and fetal growth
0.000 0.598 0.402
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.000 0.598 0.402
H02.7 Other degenerative disorders of eyelid and periocular area
0.000 0.598 0.402
H02.2 Lagophthalmos
0.000 0.598 0.402
K92 Other diseases of digestive system
0.000 0.599 0.401
U89 Agent resistant to other and unspecified antibiotics
0.000 0.600 0.400
E83.5 Disorders of calcium metabolism
0.000 0.600 0.400
K75.9 Inflammatory liver disease, unspecified
0.000 0.601 0.399
I12.9 Hypertensive renal disease without renal failure
0.000 0.601 0.399
K71.9 Toxic liver disease, unspecified
0.000 0.602 0.398
K71.8 Toxic liver disease with other disorders of liver
0.000 0.602 0.398
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.602 0.398
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.602 0.398
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.602 0.398
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.602 0.398
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.602 0.398
K71.2 Toxic liver disease with acute hepatitis
0.000 0.602 0.398
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.602 0.398
K71.0 Toxic liver disease with cholestasis
0.000 0.602 0.398
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.602 0.398
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.602 0.398
N81.0 Female urethrocele
0.397 0.603 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.605 0.395
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.605 0.395
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.605 0.395
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.605 0.395
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.605 0.395
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.605 0.395
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.605 0.395
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.605 0.395
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.605 0.395
H47.0 Disorders of optic nerve, not elsewhere classified
0.000 0.606 0.394
H94.8 Other specified disorders of ear in diseases classified elsewhere
0.000 0.606 0.393
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere
0.000 0.606 0.393
H31.0 Chorioretinal scars
0.000 0.607 0.393
L27 Dermatitis due to substances taken internally
0.000 0.608 0.392
H83.0 Labyrinthitis
0.000 0.609 0.391
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.609 0.391
E46 Unspecified protein-energy malnutrition
0.000 0.609 0.391
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.609 0.390
D50-D53 Nutritional anaemias
0.000 0.611 0.389
E86 Volume depletion
0.000 0.612 0.388
H05.2 Exophthalmic conditions
0.000 0.612 0.388
I11 Hypertensive heart disease
0.000 0.613 0.387
H13 Disorders of conjunctiva in diseases classified elsewhere
0.000 0.613 0.387
H93.9 Disorder of ear, unspecified
0.000 0.613 0.387
H93.3 Disorders of acoustic nerve
0.000 0.613 0.387
H93.2 Other abnormal auditory perceptions
0.000 0.613 0.387
H93.0 Degenerative and vascular disorders of ear
0.000 0.613 0.387
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.613 0.387
K75.2 Nonspecific reactive hepatitis
0.000 0.613 0.387
K75.1 Phlebitis of portal vein
0.000 0.613 0.387
I02 Rheumatic chorea
0.000 0.613 0.386
I01 Rheumatic fever with heart involvement
0.000 0.613 0.386
I00 Rheumatic fever without mention of heart involvement
0.000 0.613 0.386
E04.0 Non-toxic diffuse goitre
0.000 0.614 0.386
H47.7 Disorder of visual pathways, unspecified
0.000 0.615 0.385
H47.6 Disorders of visual cortex
0.000 0.615 0.385
H47.5 Disorders of other visual pathways
0.000 0.615 0.385
H47.4 Disorders of optic chiasm
0.000 0.615 0.385
H47.2 Optic atrophy
0.000 0.615 0.385
H30.9 Chorioretinal inflammation, unspecified
0.000 0.615 0.385
H30.8 Other chorioretinal inflammations
0.000 0.615 0.385
H30.2 Posterior cyclitis
0.000 0.615 0.385
H30.1 Disseminated chorioretinal inflammation
0.000 0.615 0.385
H30.0 Focal chorioretinal inflammation
0.000 0.615 0.385
H32.8 Other chorioretinal disorders in diseases classified elsewhere
0.000 0.615 0.385
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
0.000 0.615 0.385
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.615 0.385
H00.0 Hordeolum and other deep inflammation of eyelid
0.000 0.617 0.383
H04.8 Other disorders of lachrymal system
0.000 0.617 0.383
H31.9 Disorder of choroid, unspecified
0.000 0.617 0.382
H31.4 Choroidal detachment
0.000 0.617 0.382

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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