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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9501626
log Bayes Factor = 38.8676
Chromosome 6   position 32,400,344  (GRCh37) Explore rs9501626 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.001 0.999
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.001 0.999
L40 Psoriasis
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.001 0.999
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.002 0.998
H36 Retinal disorders in diseases classified elsewhere
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.000 0.003 0.997
M05 Seropositive rheumatoid arthritis
0.000 0.004 0.996
M35.3 Polymyalgia rheumatica
0.000 0.004 0.996
Chapter X Diseases of the respiratory system
0.000 0.005 0.995
H36.0 Diabetic retinopathy
0.000 0.005 0.995
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.005 0.995
E10.1 With ketoacidosis
0.000 0.006 0.994
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.007 0.993
M35 Other systemic involvement of connective tissue
0.000 0.008 0.992
J20-J22 Other acute lower respiratory infections
0.000 0.008 0.992
L40.5 Arthropathic psoriasis
0.000 0.008 0.992
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.008 0.992
E05.9 Thyrotoxicosis, unspecified
0.000 0.009 0.991
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.009 0.991
M20-M25 Other joint disorders
0.000 0.011 0.989
L40.9 Psoriasis, unspecified
0.000 0.011 0.989
J22 Unspecified acute lower respiratory infection
0.000 0.012 0.988
H02 Other disorders of eyelid
0.000 0.015 0.985
E20-E35 Disorders of other endocrine glands
0.000 0.019 0.981
E27 Other disorders of adrenal gland
0.000 0.020 0.980
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.024 0.976
E11 Non-insulin-dependent diabetes mellitus
0.000 0.028 0.972
E27.1 Primary adrenocortical insufficiency
0.000 0.029 0.971
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.040 0.960
H04 Disorders of lachrymal system
0.000 0.041 0.959
H02.1 Ectropion of eyelid
0.000 0.041 0.959
H33 Retinal detachments and breaks
0.000 0.043 0.957
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.043 0.957
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.046 0.954
H02.0 Entropion and trichiasis of eyelid
0.000 0.065 0.935
M07 Psoriatic and enteropathic arthropathies
0.000 0.074 0.926
J84 Other interstitial pulmonary diseases
0.000 0.077 0.923
E11.3 With ophthalmic complications
0.000 0.078 0.922
E10.4 With neurological complications
0.000 0.082 0.918
H33.2 Serous retinal detachment
0.000 0.083 0.917
K90.0 Coeliac disease
0.914 0.086 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.093 0.907
M06.0 Seronegative rheumatoid arthritis
0.000 0.095 0.905
E10.2 With renal complications
0.000 0.097 0.903
M31 Other necrotising vasculopathies
0.000 0.098 0.902
E10.5 With peripheral circulatory complications
0.000 0.099 0.901
J40-J47 Chronic lower respiratory diseases
0.000 0.101 0.899
H33.3 Retinal breaks without detachment
0.000 0.104 0.896
L20-L30 Dermatitis and eczema
0.000 0.109 0.891
H04.5 Stenosis and insufficiency of lachrymal passages
0.000 0.112 0.888
D50-D53 Nutritional anaemias
0.000 0.116 0.884
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.116 0.884
D60-D64 Aplastic and other anaemias
0.000 0.117 0.883
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.126 0.874
M07.3 Other psoriatic arthropathies
0.000 0.128 0.872
J47 Bronchiectasis
0.000 0.131 0.869
M80-M85 Disorders of bone density and structure
0.000 0.134 0.866
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.135 0.865
E11.1 With ketoacidosis
0.000 0.138 0.862
J80 Adult respiratory distress syndrome
0.000 0.138 0.862
J00-J06 Acute upper respiratory infections
0.000 0.145 0.855
E11.4 With neurological complications
0.000 0.146 0.854
M80 Osteoporosis with pathological fracture
0.000 0.147 0.853
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.154 0.846
H04.2 Epiphora
0.000 0.163 0.837
E27.8 Other specified disorders of adrenal gland
0.000 0.164 0.836
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.164 0.836
M31.3 Wegener's granulomatosis
0.000 0.165 0.835
J44 Other chronic obstructive pulmonary disease
0.000 0.169 0.831
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.173 0.827
H33.4 Traction detachment of retina
0.000 0.175 0.825
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.000 0.182 0.818
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.182 0.818
H02.9 Disorder of eyelid, unspecified
0.000 0.182 0.818
E14 Unspecified diabetes mellitus
0.000 0.182 0.818
M34 Systemic sclerosis
0.000 0.183 0.817
L40.0 Psoriasis vulgaris
0.000 0.185 0.815
M06.3 Rheumatoid nodule
0.000 0.189 0.811
E27.2 Addisonian crisis
0.000 0.196 0.804
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.197 0.803
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.201 0.799
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.202 0.798
E50-E64 Other nutritional deficiencies
0.000 0.202 0.798
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.203 0.797
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.208 0.792
J20 Acute bronchitis
0.000 0.208 0.792
D62 Acute posthaemorrhagic anaemia
0.000 0.209 0.791
M35.0 Sicca syndrome [Sjogren]
0.000 0.210 0.790
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.000 0.210 0.790
E11.2 With renal complications
0.000 0.211 0.789
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.212 0.788
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.000 0.214 0.786
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.217 0.783
E23 Hypofunction and other disorders of pituitary gland
0.000 0.217 0.783
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.218 0.782
H04.8 Other disorders of lachrymal system
0.000 0.219 0.781
D50 Iron deficiency anaemia
0.000 0.220 0.780
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.223 0.777
J00 Acute nasopharyngitis [common cold]
0.000 0.224 0.776
L29 Pruritus
0.000 0.225 0.775
M06.4 Inflammatory polyarthropathy
0.000 0.225 0.775
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.226 0.774
H53-H54 Visual disturbances and blindness
0.000 0.227 0.773
E70-E90 Metabolic disorders
0.000 0.227 0.773
D64 Other anaemias
0.000 0.229 0.771
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.230 0.770
E11.5 With peripheral circulatory complications
0.000 0.231 0.769
D80-D89 Certain disorders involving the immune mechanism
0.000 0.232 0.768
L42 Pityriasis rosea
0.000 0.236 0.764
E10.8 With unspecified complications
0.000 0.237 0.763
E20 Hypoparathyroidism
0.000 0.239 0.761
L28 Lichen simplex chronicus and prurigo
0.000 0.241 0.759
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.243 0.757
M30 Polyarteritis nodosa and related conditions
0.000 0.244 0.756
J40 Bronchitis, not specified as acute or chronic
0.000 0.244 0.756
H02.5 Other disorders affecting eyelid function
0.000 0.248 0.752
E04 Other non-toxic goitre
0.000 0.248 0.752
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.255 0.745
H10-H13 Disorders of conjunctiva
0.000 0.256 0.744
M32 Systemic lupus erythematosus
0.000 0.258 0.741
H02.4 Ptosis of eyelid
0.000 0.267 0.733
L57.0 Actinic keratosis
0.000 0.269 0.731
J04 Acute laryngitis and tracheitis
0.000 0.270 0.730
M14 Arthropathies in other diseases classified elsewhere
0.000 0.271 0.729
E06 Thyroiditis
0.000 0.271 0.729
M91-M94 Chondropathies
0.000 0.272 0.728
E10.6 With other specified complications
0.000 0.273 0.727
E11.8 With unspecified complications
0.000 0.274 0.726
J21 Acute bronchiolitis
0.000 0.276 0.724
D86 Sarcoidosis
0.000 0.279 0.721
M35.7 Hypermobility syndrome
0.000 0.280 0.720
E07 Other disorders of thyroid
0.000 0.280 0.720
J81 Pulmonary oedema
0.000 0.281 0.719
E86 Volume depletion
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M12 Other specific arthropathies
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
L40.8 Other psoriasis
0.000 0.284 0.716
L40.4 Guttate psoriasis
0.000 0.284 0.716
L40.3 Pustulosis palmaris et plantaris
0.000 0.284 0.716
L40.2 Acrodermatitis continua
0.000 0.284 0.716
L40.1 Generalised pustular psoriasis
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
H30 Chorioretinal inflammation
0.000 0.284 0.716
L44 Other papulosquamous disorders
0.000 0.284 0.716
L41 Parapsoriasis
0.000 0.284 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.285 0.714
H35 Other retinal disorders
0.000 0.286 0.714
M05.8 Other seropositive rheumatoid arthritis
0.000 0.286 0.714
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.286 0.714
M05.2 Rheumatoid vasculitis
0.000 0.286 0.714
M05.1 Rheumatoid lung disease
0.000 0.286 0.714
M05.0 Felty's syndrome
0.000 0.286 0.714
E27.9 Disorder of adrenal gland, unspecified
0.000 0.288 0.712
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.288 0.712
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.288 0.712
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.288 0.712
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.288 0.712
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.288 0.712
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.288 0.712
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.288 0.712
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.288 0.712
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.289 0.711
M35.8 Other specified systemic involvement of connective tissue
0.000 0.289 0.711
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.289 0.711
M35.5 Multifocal fibrosclerosis
0.000 0.289 0.711
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.289 0.711
M35.2 Behcet's disease
0.000 0.289 0.711
M35.1 Other overlap syndromes
0.000 0.289 0.711
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.291 0.709
H02.6 Xanthelasma of eyelid
0.000 0.291 0.709
H02.7 Other degenerative disorders of eyelid and periocular area
0.000 0.293 0.706
H04.3 Acute and unspecified inflammation of lachrymal passages
0.000 0.295 0.705
D50.8 Other iron deficiency anaemias
0.000 0.296 0.704
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.297 0.703
E32 Diseases of thymus
0.000 0.297 0.703
E31 Polyglandular dysfunction
0.000 0.297 0.703
E30 Disorders of puberty, not elsewhere classified
0.000 0.297 0.703
E25 Adrenogenital disorders
0.000 0.297 0.703
E27.5 Adrenomedullary hyperfunction
0.000 0.297 0.702
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.297 0.702
E27.0 Other adrenocortical overactivity
0.000 0.297 0.702
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.298 0.702
D64.9 Anaemia, unspecified
0.000 0.300 0.700
H16 Keratitis
0.000 0.300 0.700
E55 Vitamin D deficiency
0.000 0.301 0.699
H53 Visual disturbances
0.000 0.301 0.699
E11.7 With multiple complications
0.000 0.303 0.697
D51 Vitamin B12 deficiency anaemia
0.000 0.305 0.695
D53 Other nutritional anaemias
0.000 0.306 0.694
H04.4 Chronic inflammation of lachrymal passages
0.000 0.307 0.693
E29 Testicular dysfunction
0.000 0.309 0.691
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.310 0.690
E14.3 With ophthalmic complications
0.000 0.310 0.690
H04.6 Other changes in lachrymal passages
0.000 0.312 0.688
H04.0 Dacryoadenitis
0.000 0.312 0.688
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.316 0.684
L10-L14 Bullous disorders
0.000 0.316 0.684
L29.0 Pruritus ani
0.000 0.319 0.681
L30 Other dermatitis
0.000 0.323 0.677
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.323 0.676
D50.9 Iron deficiency anaemia, unspecified
0.000 0.324 0.676
M06.34 Rheumatoid nodule (Hand)
0.000 0.325 0.675
D55-D59 Haemolytic anaemias
0.000 0.326 0.674
M31.6 Other giant cell arteritis
0.000 0.328 0.672
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.329 0.671
H35.8 Other specified retinal disorders
0.000 0.329 0.671
D86.9 Sarcoidosis, unspecified
0.000 0.330 0.670
H02.2 Lagophthalmos
0.000 0.332 0.668
H46 Optic neuritis
0.000 0.332 0.668
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.000 0.333 0.667
E26 Hyperaldosteronism
0.000 0.333 0.666
J04.0 Acute laryngitis
0.000 0.334 0.666
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.334 0.666
L28.0 Lichen simplex chronicus
0.000 0.335 0.665
L20 Atopic dermatitis
0.000 0.335 0.665
M07.6 Other enteropathic arthropathies
0.000 0.336 0.664
M07.5 Arthropathy in ulcerative colitis
0.000 0.336 0.664
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.336 0.664
M07.2 Psoriatic spondylitis
0.000 0.336 0.664
M07.1 Arthritis mutilans
0.000 0.336 0.664
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.336 0.664
H04.1 Other disorders of lachrymal gland
0.000 0.338 0.662
J84.0 Alveolar and parietoalveolar conditions
0.000 0.338 0.662
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.340 0.660
D52 Folate deficiency anaemia
0.000 0.343 0.657
L43 Lichen planus
0.000 0.344 0.656
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.351 0.649
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.351 0.649
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.351 0.649
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.351 0.649
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.351 0.649
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.351 0.649
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.351 0.649
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.351 0.649
H03 Disorders of eyelid in diseases classified elsewhere
0.000 0.351 0.649
D61 Other aplastic anaemias
0.000 0.351 0.649
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.351 0.649
J20.9 Acute bronchitis, unspecified
0.000 0.351 0.649
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.353 0.647
M31.9 Necrotising vasculopathy, unspecified
0.000 0.353 0.647
M31.8 Other specified necrotising vasculopathies
0.000 0.353 0.647
M31.7 Microscopic polyangiitis
0.000 0.353 0.647
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.353 0.647
M31.2 Lethal midline granuloma
0.000 0.353 0.647
M31.1 Thrombotic microangiopathy
0.000 0.353 0.647
M31.0 Hypersensitivity angiitis
0.000 0.353 0.647
H16.0 Corneal ulcer
0.000 0.353 0.647
J41 Simple and mucopurulent chronic bronchitis
0.000 0.356 0.644
E11.6 With other specified complications
0.000 0.356 0.644
E16 Other disorders of pancreatic internal secretion
0.000 0.356 0.644
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.000 0.359 0.641
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.359 0.641
M34.1 CR(E)ST syndrome
0.000 0.359 0.641
J01 Acute sinusitis
0.000 0.360 0.640
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.360 0.639
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.000 0.361 0.639
L24 Irritant contact dermatitis
0.000 0.361 0.639
L23 Allergic contact dermatitis
0.000 0.361 0.639
L21 Seborrhoeic dermatitis
0.000 0.361 0.639
L26 Exfoliative dermatitis
0.000 0.361 0.639
L22 Diaper [napkin] dermatitis
0.000 0.361 0.639
H34 Retinal vascular occlusions
0.000 0.361 0.638
H18 Other disorders of cornea
0.000 0.362 0.638
H06.2 Dysthyroid exophthalmos
0.000 0.363 0.637
H53.9 Visual disturbance, unspecified
0.000 0.364 0.636
H53.1 Subjective visual disturbances
0.000 0.365 0.635
E40-E46 Malnutrition
0.000 0.365 0.635
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.366 0.634
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.367 0.633
L29.2 Pruritus vulvae
0.000 0.367 0.633
L25 Unspecified contact dermatitis
0.000 0.368 0.632
E05.8 Other thyrotoxicosis
0.000 0.368 0.631
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.370 0.630
E24 Cushing's syndrome
0.000 0.370 0.630
J02 Acute pharyngitis
0.000 0.371 0.629
E55.9 Vitamin D deficiency, unspecified
0.000 0.372 0.628
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.373 0.627
L58 Radiodermatitis
0.000 0.373 0.627
L55 Sunburn
0.000 0.373 0.627
M24 Other specific joint derangements
0.000 0.374 0.626
M34.9 Systemic sclerosis, unspecified
0.000 0.374 0.626
M07.38 Other psoriatic arthropathies (Other)
0.000 0.374 0.625
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.374 0.625
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.374 0.625
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.374 0.625
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.374 0.625
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.374 0.625
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.374 0.625
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.374 0.625
H04.9 Disorder of lachrymal system, unspecified
0.000 0.375 0.625
H00 Hordeolum and chalazion
0.000 0.376 0.624
E23.0 Hypopituitarism
0.000 0.376 0.624
H11 Other disorders of conjunctiva
0.000 0.377 0.623
M34.8 Other forms of systemic sclerosis
0.000 0.379 0.621
M83 Adult osteomalacia
0.000 0.379 0.621
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.381 0.619
J84.8 Other specified interstitial pulmonary diseases
0.000 0.382 0.618
H35.4 Peripheral retinal degeneration
0.000 0.385 0.615
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.386 0.614
H02.8 Other specified disorders of eyelid
0.000 0.388 0.612
M80.8 Other osteoporosis with pathological fracture
0.000 0.388 0.612
M80.4 Drug-induced osteoporosis with pathological fracture
0.000 0.388 0.612
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.000 0.388 0.612
M80.2 Osteoporosis of disuse with pathological fracture
0.000 0.388 0.612
M00-M03 Infectious arthropathies
0.000 0.388 0.611
H31 Other disorders of choroid
0.000 0.390 0.609
M11 Other crystal arthropathies
0.000 0.393 0.607
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)
0.000 0.393 0.607
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)
0.000 0.393 0.607
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)
0.000 0.393 0.607
M80.94 Unspecified osteoporosis with pathological fracture (Hand)
0.000 0.393 0.607
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)
0.000 0.393 0.607
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)
0.000 0.393 0.607
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)
0.000 0.393 0.607
H05 Disorders of orbit
0.000 0.395 0.605
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.396 0.604
E20.9 Hypoparathyroidism, unspecified
0.000 0.397 0.603
M82 Osteoporosis in diseases classified elsewhere
0.000 0.398 0.602
E04.2 Non-toxic multinodular goitre
0.000 0.399 0.601
H35.6 Retinal haemorrhage
0.000 0.401 0.598
E28 Ovarian dysfunction
0.000 0.402 0.598
E89.0 Postprocedural hypothyroidism
0.000 0.402 0.598
L98.8 Other specified disorders of skin and subcutaneous tissue
0.000 0.403 0.597
E04.9 Non-toxic goitre, unspecified
0.000 0.405 0.595
D86.1 Sarcoidosis of lymph nodes
0.000 0.405 0.595
Chapter XXII Codes for special purposes
0.000 0.407 0.593
E04.0 Non-toxic diffuse goitre
0.000 0.408 0.591
M33 Dermatopolymyositis
0.000 0.409 0.591
H55-H59 Other disorders of eye and adnexa
0.000 0.410 0.590
H01 Other inflammation of eyelid
0.000 0.410 0.590
E11.0 With coma
0.000 0.412 0.588
H33.1 Retinoschisis and retinal cysts
0.000 0.412 0.588
E14.8 With unspecified complications
0.000 0.414 0.586
E14.7 With multiple complications
0.000 0.414 0.586
E14.6 With other specified complications
0.000 0.414 0.586
E14.5 With peripheral circulatory complications
0.000 0.414 0.586
E14.4 With neurological complications
0.000 0.414 0.586
E14.2 Withrenal complications
0.000 0.414 0.586
E14.1 With ketoacidosis
0.000 0.414 0.586
E14.0 With coma
0.000 0.414 0.586
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.000 0.414 0.586
E23.2 Diabetes insipidus
0.000 0.414 0.586
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.414 0.586
M34.0 Progressive systemic sclerosis
0.000 0.414 0.586
L98.0 Pyogenic granuloma
0.000 0.415 0.585
E07.8 Other specified disorders of thyroid
0.000 0.416 0.584
M60-M63 Disorders of muscles
0.000 0.418 0.582
E03.8 Other specified hypothyroidism
0.000 0.418 0.581
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.419 0.581
M06.38 Rheumatoid nodule (Other)
0.000 0.419 0.581
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.419 0.581
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.419 0.581
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.419 0.581
M06.33 Rheumatoid nodule (Forearm)
0.000 0.419 0.581
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.419 0.581
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.419 0.581
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.419 0.581
E14.9 Without complications
0.000 0.419 0.581
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.419 0.581
E73 Lactose intolerance
0.000 0.422 0.578
H21 Other disorders of iris and ciliary body
0.000 0.422 0.578
L98.4 Chronic ulcer of skin, not elsewhere classified
0.000 0.425 0.575
E53 Deficiency of other B group vitamins
0.000 0.425 0.574
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.428 0.572
E63 Other nutritional deficiencies
0.000 0.428 0.572
E56 Other vitamin deficiencies
0.000 0.428 0.572
E51 Thiamine deficiency
0.000 0.428 0.572
E50 Vitamin A deficiency
0.000 0.428 0.572
E60 Dietary zinc deficiency
0.000 0.428 0.572
E59 Dietary selenium deficiency
0.000 0.428 0.572
E58 Dietary calcium deficiency
0.000 0.428 0.572
E54 Ascorbic acid deficiency
0.000 0.428 0.572
E52 Niacin deficiency [pellagra]
0.000 0.428 0.572
M80.0 Postmenopausal osteoporosis with pathological fracture
0.000 0.429 0.570
E06.9 Thyroiditis, unspecified
0.000 0.431 0.569
E78.2 Mixed hyperlipidaemia
0.000 0.432 0.568
E15 Nondiabetic hypoglycaemic coma
0.000 0.432 0.568
J20.8 Acute bronchitis due to other specified organisms
0.000 0.432 0.568
J20.7 Acute bronchitis due to echovirus
0.000 0.432 0.568
J20.6 Acute bronchitis due to rhinovirus
0.000 0.432 0.568
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.432 0.568
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.432 0.568
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.432 0.568
J20.2 Acute bronchitis due to streptococcus
0.000 0.432 0.568
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.432 0.568
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.432 0.568
L60-L75 Disorders of skin appendages
0.000 0.433 0.567
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.434 0.566
H18.6 Keratoconus
0.000 0.434 0.566
M32.1 Systemic lupus erythematosus with organ or system involvement
0.000 0.436 0.564
H06.3 Other disorders of orbit in diseases classified elsewhere
0.000 0.436 0.564
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.000 0.436 0.564
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.000 0.436 0.564
H18.4 Corneal degeneration
0.000 0.438 0.562
L57.5 Actinic granuloma
0.000 0.438 0.562
L57.3 Poikiloderma of Civatte
0.000 0.438 0.562
L57.2 Cutis rhomboidalis nuchae
0.000 0.438 0.562
L57.1 Actinic reticuloid
0.000 0.438 0.562
E23.7 Disorder of pituitary gland, unspecified
0.000 0.438 0.561
E23.6 Other disorders of pituitary gland
0.000 0.438 0.561
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.438 0.561
E23.1 Drug-induced hypopituitarism
0.000 0.438 0.561
L30.8 Other specified dermatitis
0.000 0.439 0.561
D50.1 Sideropenic dysphagia
0.000 0.441 0.559
H17 Corneal scars and opacities
0.000 0.441 0.558
D53.9 Nutritional anaemia, unspecified
0.000 0.442 0.558
Chapter I Certain infectious and parasitic diseases
0.000 0.444 0.556
L29.3 Anogenital pruritus, unspecified
0.000 0.444 0.556
L29.1 Pruritus scroti
0.000 0.444 0.556
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.444 0.556
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.444 0.556
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.444 0.556
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.444 0.556
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.444 0.556
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.444 0.556
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.444 0.556
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.444 0.556
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.444 0.556
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.000 0.445 0.555
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.446 0.554
E84 Cystic fibrosis
0.000 0.446 0.554
E79 Disorders of purine and pyrimidine metabolism
0.000 0.446 0.554
E77 Disorders of glycoprotein metabolism
0.000 0.446 0.554
E76 Disorders of glycosaminoglycan metabolism
0.000 0.446 0.554
E72 Other disorders of amino-acid metabolism
0.000 0.446 0.554
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.446 0.554
E70 Disorders of aromatic amino-acid metabolism
0.000 0.446 0.554
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.446 0.554
H35.7 Separation of retinal layers
0.000 0.446 0.554
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.447 0.553
E16.2 Hypoglycaemia, unspecified
0.000 0.447 0.553
D64.4 Congenital dyserythropoietic anaemia
0.000 0.447 0.552
D64.3 Other sideroblastic anaemias
0.000 0.447 0.552
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.447 0.552
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.447 0.552
D64.0 Hereditary sideroblastic anaemia
0.000 0.447 0.552
L29.8 Other pruritus
0.000 0.448 0.552
D86.0 Sarcoidosis of lung
0.000 0.448 0.552
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.449 0.551
M86-M90 Other osteopathies
0.000 0.449 0.551
D82 Immunodeficiency associated with other major defects
0.000 0.449 0.550
D81 Combined immunodeficiencies
0.000 0.449 0.550
M30.0 Polyarteritis nodosa
0.000 0.453 0.547
E20.8 Other hypoparathyroidism
0.000 0.454 0.545
E20.1 Pseudohypoparathyroidism
0.000 0.454 0.545
E20.0 Idiopathic hypoparathyroidism
0.000 0.454 0.545
E89.3 Postprocedural hypopituitarism
0.000 0.455 0.545
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.000 0.455 0.545
L28.2 Other prurigo
0.000 0.455 0.544
L28.1 Prurigo nodularis
0.000 0.455 0.544
E65-E68 Obesity and other hyperalimentation
0.000 0.456 0.544
L80 Vitiligo
0.000 0.457 0.543
H15 Disorders of sclera
0.000 0.458 0.542
M30.8 Other conditions related to polyarteritis nodosa
0.000 0.458 0.542
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.000 0.458 0.542
M30.2 Juvenile polyarteritis
0.000 0.458 0.542
M94 Other disorders of cartilage
0.000 0.458 0.542
M21 Other acquired deformities of limbs
0.000 0.458 0.542
E04.8 Other specified non-toxic goitre
0.000 0.461 0.539
E74 Other disorders of carbohydrate metabolism
0.000 0.461 0.539
H00.0 Hordeolum and other deep inflammation of eyelid
0.000 0.462 0.538
E13 Other specified diabetes mellitus
0.001 0.463 0.537
M14.6 Neuropathic arthropathy
0.000 0.465 0.535

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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