TreeWAS – Variant ID: rs9525562

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H52.1 Myopia	0.050	0.950	0.000
H52 Disorders of refraction and accommodation	0.045	0.955	0.000
H52.7 Disorder of refraction, unspecified	0.042	0.958	0.000
H52.3 Anisometropia and aniseikonia	0.039	0.961	0.000
H52.0 Hypermetropia	0.036	0.964	0.000
H52.2 Astigmatism	0.035	0.965	0.000
H52.6 Other disorders of refraction	0.033	0.967	0.000
H52.5 Disorders of accommodation	0.033	0.967	0.000
H52.4 Presbyopia	0.028	0.972	0.000
J33.0 Polyp of nasal cavity	0.000	0.976	0.024
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.022	0.978	0.000
H49 Paralytic strabismus	0.018	0.982	0.000
H51 Other disorders of binocular movement	0.017	0.983	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.983	0.017
H49.1 Fourth [trochlear] nerve palsy	0.016	0.984	0.000
H49.2 Sixth [abducent] nerve palsy	0.016	0.984	0.000
K86 Other diseases of pancreas	0.000	0.984	0.016
K86.1 Other chronic pancreatitis	0.000	0.984	0.016
Z00.0 General medical examination	0.000	0.985	0.015
H51.8 Other specified disorders of binocular movement	0.014	0.985	0.000
K86.8 Other specified diseases of pancreas	0.000	0.985	0.015
H49.4 Progressive external ophthalmoplegia	0.014	0.986	0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.000	0.986	0.014
H49.3 Total (external) ophthalmoplegia	0.013	0.987	0.000
Z00.5 Examination of potential donor of organ and tissue	0.000	0.987	0.013
H50 Other strabismus	0.013	0.987	0.000
H51.9 Disorder of binocular movement, unspecified	0.012	0.987	0.000
H51.1 Convergence insufficiency and excess	0.012	0.987	0.000
H51.0 Palsy of conjugate gaze	0.012	0.987	0.000
H49.8 Other paralytic strabismus	0.012	0.988	0.000
H49.9 Paralytic strabismus, unspecified	0.012	0.988	0.000
Z00.4 General psychiatric examination, not elsewhere classified	0.000	0.988	0.012
H51.2 Internuclear ophthalmoplegia	0.011	0.989	0.000
Z00.6 Examination for normal comparison and control in clinical research programme	0.000	0.989	0.011
H50.0 Convergent concomitant strabismus	0.011	0.989	0.000
H50.4 Other and unspecified heterotropia	0.011	0.989	0.000
K86.3 Pseudocyst of pancreas	0.000	0.989	0.011
Z00.8 Other general examinations	0.000	0.990	0.010
K86.2 Cyst of pancreas	0.000	0.990	0.010
H50.6 Mechanical strabismus	0.010	0.990	0.000
Z00.3 Examination for adolescent development state	0.000	0.990	0.010
Z00.2 Examination for period of rapid growth in childhood	0.000	0.990	0.010
Z00.1 Routine child health examination	0.000	0.990	0.010
K86.9 Disease of pancreas, unspecified	0.000	0.990	0.010
H50.3 Intermittent heterotropia	0.009	0.990	0.000
K83.8 Other specified diseases of biliary tract	0.000	0.991	0.009
H50.5 Heterophoria	0.009	0.991	0.000
H49.0 Third [oculomotor] nerve palsy	0.008	0.992	0.000
H50.8 Other specified strabismus	0.008	0.992	0.000
K82.4 Cholesterolosis of gallbladder	0.000	0.992	0.008
H50.1 Divergent concomitant strabismus	0.008	0.992	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.008	0.992	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.008	0.992	0.000
Q38.7 Pharyngeal pouch	0.007	0.993	0.000
H50.2 Vertical strabismus	0.007	0.993	0.000
Q40 Other congenital malformations of upper alimentary tract	0.007	0.993	0.000
K83.9 Disease of biliary tract, unspecified	0.000	0.993	0.007
H50.9 Strabismus, unspecified	0.007	0.993	0.000
K83 Other diseases of biliary tract	0.000	0.993	0.007
Q61 Cystic kidney disease	0.007	0.993	0.000
Q60-Q64 Congenital malformations of the urinary system	0.007	0.993	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.993	0.007
Q43 Other congenital malformations of intestine	0.007	0.993	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.006	0.994	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.006	0.994	0.000
Q61.5 Medullary cystic kidney	0.006	0.994	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.006	0.994	0.000
Q38.1 Ankyloglossia	0.006	0.994	0.000
Q40.1 Congenital hiatus hernia	0.006	0.994	0.000
Q61.2 Polycystic kidney, adult type	0.006	0.994	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.006	0.994	0.000
Q38.8 Other congenital malformations of pharynx	0.006	0.994	0.000
I35.1 Aortic (valve) insufficiency	0.000	0.994	0.006
Q40.2 Other specified congenital malformations of stomach	0.006	0.994	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.006	0.994	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.006	0.994	0.000
Q38.3 Other congenital malformations of tongue	0.006	0.994	0.000
Q38.2 Macroglossia	0.006	0.994	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.006	0.994	0.000
Q50-Q56 Congenital malformations of genital organs	0.006	0.994	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.006	0.994	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.006	0.994	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.994	0.006
Q38.6 Other congenital malformations of mouth	0.006	0.994	0.000
Q43.1 Hirschsprung's disease	0.006	0.994	0.000
Q45 Other congenital malformations of digestive system	0.006	0.994	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.005	0.994	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.005	0.994	0.000
J95.8 Other postprocedural respiratory disorders	0.000	0.994	0.006
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.995	0.005
Q64 Other congenital malformations of urinary system	0.005	0.995	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.005	0.995	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.000	0.995	0.005
Q50.4 Embryonic cyst of Fallopian tube	0.005	0.995	0.000
S64.4 Injury of digital nerve of other finger	0.000	0.995	0.005
Q60 Renal agenesis and other reduction defects of kidney	0.005	0.995	0.000
E53 Deficiency of other B group vitamins	0.000	0.995	0.005
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.005	0.995	0.000
K83.4 Spasm of sphincter of Oddi	0.000	0.995	0.005
Q43.3 Congenital malformations of intestinal fixation	0.005	0.995	0.000
E53.9 Vitamin B deficiency, unspecified	0.000	0.995	0.005
M96.8 Other postprocedural musculoskeletal disorders	0.000	0.995	0.005
Q43.0 Meckel's diverticulum	0.005	0.995	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.995	0.005
K83.5 Biliary cyst	0.000	0.995	0.005
Q43.9 Congenital malformation of intestine, unspecified	0.005	0.995	0.000
Q61.3 Polycystic kidney, unspecified	0.005	0.995	0.000
Q61.8 Other cystic kidney diseases	0.005	0.995	0.000
Q61.1 Polycystic kidney, infantile type	0.005	0.995	0.000
Q63 Other congenital malformations of kidney	0.005	0.995	0.000
K83.3 Fistula of bile duct	0.000	0.995	0.005
Q43.7 Persistent cloaca	0.005	0.995	0.000
Q43.6 Congenital fistula of rectum and anus	0.005	0.995	0.000
Q43.5 Ectopic anus	0.005	0.995	0.000
Q43.4 Duplication of intestine	0.005	0.995	0.000
Q43.2 Other congenital functional disorders of colon	0.005	0.995	0.000
Q61.9 Cystic kidney disease, unspecified	0.005	0.995	0.000
S22.40 Multiple fractures of ribs (closed)	0.005	0.995	0.000
K82 Other diseases of gallbladder	0.000	0.995	0.005
Q61.0 Congenital single renal cyst	0.005	0.995	0.000
Q52 Other congenital malformations of female genitalia	0.005	0.995	0.000
Q39 Congenital malformations of oesophagus	0.005	0.995	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.995	0.005
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.005	0.995	0.000
Q60.3 Renal hypoplasia, unilateral	0.005	0.995	0.000
Q53 Undescended testicle	0.005	0.995	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.000	0.995	0.005
Q61.4 Renal dysplasia	0.005	0.995	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.995	0.005
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.005	0.995	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.005	0.995	0.000
Q44.7 Other congenital malformations of liver	0.005	0.995	0.000
Q35-Q37 Cleft lip and cleft palate	0.005	0.995	0.000
Q00-Q07 Congenital malformations of the nervous system	0.005	0.995	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.005	0.995	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.005	0.995	0.000
Q44.4 Choledochal cyst	0.004	0.995	0.000
Q55 Other congenital malformations of male genital organs	0.004	0.995	0.000
R10.2 Pelvic and perineal pain	0.005	0.995	0.000
K83.2 Perforation of bile duct	0.000	0.996	0.004
Q56 Indeterminate sex and pseudohermaphroditism	0.004	0.996	0.000
Q44.6 Cystic disease of liver	0.004	0.996	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.004	0.996	0.000
Q44.2 Atresia of bile ducts	0.004	0.996	0.000
Q44.1 Other congenital malformations of gallbladder	0.004	0.996	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.004	0.996	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.004	0.996	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.004	0.996	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.004	0.996	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.004	0.996	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.004	0.996	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.004	0.996	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.004	0.996	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.004	0.996	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.004	0.996	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.004	0.996	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.004	0.996	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.004	0.996	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.004	0.996	0.000
K82.9 Disease of gallbladder, unspecified	0.000	0.996	0.004
Q45.9 Congenital malformation of digestive system, unspecified	0.004	0.996	0.000
Q45.2 Congenital pancreatic cyst	0.004	0.996	0.000
Q45.1 Annular pancreas	0.004	0.996	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.004	0.996	0.000
Q43.8 Other specified congenital malformations of intestine	0.004	0.996	0.000
Q51 Congenital malformations of uterus and cervix	0.004	0.996	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.004	0.996	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.996	0.004
L81.9 Disorder of pigmentation, unspecified	0.000	0.996	0.004
Q52.1 Doubling of vagina	0.004	0.996	0.000
Q53.9 Undescended testicle, unspecified	0.004	0.996	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.004	0.996	0.000
Q64.8 Other specified congenital malformations of urinary system	0.004	0.996	0.000
Q64.6 Congenital diverticulum of bladder	0.004	0.996	0.000
Q64.5 Congenital absence of bladder and urethra	0.004	0.996	0.000
Q64.4 Malformation of urachus	0.004	0.996	0.000
Q64.2 Congenital posterior urethral valves	0.004	0.996	0.000
Q64.1 Exstrophy of urinary bladder	0.004	0.996	0.000
Q64.0 Epispadias	0.004	0.996	0.000
Q05 Spina bifida	0.004	0.996	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.004	0.996	0.000
Q50.3 Other congenital malformations of ovary	0.004	0.996	0.000
Q50.2 Congenital torsion of ovary	0.004	0.996	0.000
Q50.1 Developmental ovarian cyst	0.004	0.996	0.000
Q50.0 Congenital absence of ovary	0.004	0.996	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.004	0.996	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.000	0.996	0.004
Q45.8 Other specified congenital malformations of digestive system	0.004	0.996	0.000
Q60.6 Potter's syndrome	0.004	0.996	0.000
Q60.5 Renal hypoplasia, unspecified	0.004	0.996	0.000
Q60.4 Renal hypoplasia, bilateral	0.004	0.996	0.000
Q60.1 Renal agenesis, bilateral	0.004	0.996	0.000
E53.1 Pyridoxine deficiency	0.000	0.996	0.004
E53.0 Riboflavin deficiency	0.000	0.996	0.004
Q18 Other congenital malformations of face and neck	0.004	0.996	0.000
Q80-Q89 Other congenital malformations	0.004	0.996	0.000
Q62.8 Other congenital malformations of ureter	0.004	0.996	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.004	0.996	0.000
Q62.6 Malposition of ureter	0.004	0.996	0.000
Q62.4 Agenesis of ureter	0.004	0.996	0.000
Q62.2 Congenital megaloureter	0.004	0.996	0.000
Q62.1 Atresia and stenosis of ureter	0.004	0.996	0.000
Q62.0 Congenital hydronephrosis	0.004	0.996	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.996	0.004
Q62.5 Duplication of ureter	0.004	0.996	0.000
Q05.9 Spina bifida, unspecified	0.004	0.996	0.000
K83.1 Obstruction of bile duct	0.000	0.996	0.004
Q96 Turner's syndrome	0.004	0.996	0.000
Q24 Other congenital malformations of heart	0.004	0.996	0.000
Q50.5 Embryonic cyst of broad ligament	0.004	0.996	0.000
Q63.2 Ectopic kidney	0.004	0.996	0.000
J98.4 Other disorders of lung	0.000	0.996	0.004
Q52.5 Fusion of labia	0.004	0.996	0.000
Q55.0 Absence and aplasia of testis	0.004	0.996	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.004	0.996	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.004	0.996	0.000
A41.8 Other specified septicaemia	0.000	0.996	0.004
N39.4 Other specified urinary incontinence	0.000	0.996	0.004
Q35 Cleft palate	0.004	0.996	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.004	0.996	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.996	0.004
Q44.5 Other congenital malformations of bile ducts	0.004	0.996	0.000
Q63.8 Other specified congenital malformations of kidney	0.004	0.996	0.000
Q63.3 Hyperplastic and giant kidney	0.004	0.996	0.000
Q60.2 Renal agenesis, unspecified	0.004	0.996	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.004	0.996	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.000	0.996	0.004
Q63.1 Lobulated, fused and horseshoe kidney	0.004	0.996	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.996	0.004
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.004	0.996	0.000
Q52.4 Other congenital malformations of vagina	0.004	0.996	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.004	0.996	0.000
Q39.8 Other congenital malformations of oesophagus	0.004	0.996	0.000
Q39.5 Congenital dilatation of oesophagus	0.004	0.996	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.004	0.996	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.004	0.996	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.004	0.996	0.000
Q39.0 Atresia of oesophagus without fistula	0.004	0.996	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.004	0.996	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.004	0.996	0.000
Q52.7 Other congenital malformations of vulva	0.004	0.996	0.000
Q52.6 Congenital malformation of clitoris	0.004	0.996	0.000
Q52.3 Imperforate hymen	0.004	0.996	0.000
Q52.2 Congenital rectovaginal fistula	0.004	0.996	0.000
Q52.0 Congenital absence of vagina	0.004	0.996	0.000
Q60.0 Renal agenesis, unilateral	0.004	0.996	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.996	0.004
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.996	0.004
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.996	0.004
M95.0 Acquired deformity of nose	0.000	0.996	0.004
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.004	0.996	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.004	0.996	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.004	0.996	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.004	0.996	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.004	0.996	0.000
Q53.2 Undescended testicle, bilateral	0.004	0.996	0.000
Q53.0 Ectopic testis	0.004	0.996	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.004	0.996	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.004	0.996	0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.000	0.996	0.004
G55.0 Nerve root and plexus compressions in neoplastic disease	0.004	0.996	0.000
Q53.1 Undescended testicle, unilateral	0.004	0.996	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.003	0.996	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.003	0.996	0.000
Q13 Congenital malformations of anterior segment of eye	0.003	0.996	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.003	0.996	0.000
K04.8 Radicular cyst	0.004	0.996	0.000
Q06 Other congenital malformations of spinal cord	0.003	0.996	0.000
Q03 Congenital hydrocephalus	0.003	0.996	0.000
Q01 Encephalocele	0.003	0.996	0.000
Q00 Anencephaly and similar malformations	0.003	0.996	0.000
Q02 Microcephaly	0.003	0.996	0.000
Q36 Cleft lip	0.003	0.996	0.000
D47.4 Osteomyelofibrosis	0.000	0.996	0.004
Q34 Other congenital malformations of respiratory system	0.003	0.996	0.000
Q33 Congenital malformations of lung	0.003	0.996	0.000
Q32 Congenital malformations of trachea and bronchus	0.003	0.996	0.000
Q31 Congenital malformations of larynx	0.003	0.996	0.000
Q30 Congenital malformations of nose	0.003	0.996	0.000
Q17 Other congenital malformations of ear	0.003	0.996	0.000
K82.0 Obstruction of gallbladder	0.000	0.996	0.003
Q14 Congenital malformations of posterior segment of eye	0.003	0.996	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.996	0.003
Q54 Hypospadias	0.003	0.996	0.000
Q04 Other congenital malformations of brain	0.003	0.996	0.000
Q82 Other congenital malformations of skin	0.003	0.996	0.000
Q24.8 Other specified congenital malformations of heart	0.003	0.996	0.000
Q51.4 Unicornate uterus	0.003	0.996	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.003	0.996	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.003	0.996	0.000
Q55.5 Congenital absence and aplasia of penis	0.003	0.996	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.003	0.996	0.000
Q55.3 Atresia of vas deferens	0.003	0.996	0.000
Q55.1 Hypoplasia of testis and scrotum	0.003	0.996	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.996	0.004
Q90 Down's syndrome	0.003	0.996	0.000
Q15 Other congenital malformations of eye	0.003	0.997	0.000
Q63.0 Accessory kidney	0.003	0.997	0.000
Q56.4 Indeterminate sex, unspecified	0.003	0.997	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.003	0.997	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.003	0.997	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.003	0.997	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.003	0.997	0.000
Q12 Congenital lens malformations	0.003	0.997	0.000
Q51.3 Bicornate uterus	0.003	0.997	0.000
Q96.9 Turner's syndrome, unspecified	0.003	0.997	0.000
Q24.5 Malformation of coronary vessels	0.003	0.997	0.000
Q39.4 Oesophageal web	0.003	0.997	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.997	0.003
Q37 Cleft palate with cleft lip	0.003	0.997	0.000
Q39.6 Diverticulum of oesophagus	0.003	0.997	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.003	0.997	0.000
Q35.9 Cleft palate, unspecified	0.003	0.997	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.997	0.003
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.003	0.997	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.003	0.997	0.000
Q51.6 Embryonic cyst of cervix	0.003	0.997	0.000
Q51.5 Agenesis and aplasia of cervix	0.003	0.997	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.003	0.997	0.000
Q51.0 Agenesis and aplasia of uterus	0.003	0.997	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.003	0.997	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.997	0.003
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.003	0.997	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.000	0.997	0.003
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.000	0.997	0.003
Q05.8 Sacral spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.003	0.997	0.000
Q51.2 Other doubling of uterus	0.003	0.997	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.003	0.997	0.000
K82.3 Fistula of gallbladder	0.000	0.997	0.003
J00 Acute nasopharyngitis [common cold]	0.000	0.997	0.003
Q18.9 Congenital malformation of face and neck, unspecified	0.003	0.997	0.000
Q18.8 Other specified congenital malformations of face and neck	0.003	0.997	0.000
Q18.7 Microcheilia	0.003	0.997	0.000
Q18.6 Macrocheilia	0.003	0.997	0.000
Q18.5 Microstomia	0.003	0.997	0.000
Q18.4 Macrostomia	0.003	0.997	0.000
Q18.3 Webbing of neck	0.003	0.997	0.000
Q18.2 Other branchial cleft malformations	0.003	0.997	0.000
Q82.8 Other specified congenital malformations of skin	0.003	0.997	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.003	0.997	0.000
Q84 Other congenital malformations of integument	0.003	0.997	0.000
Q81 Epidermolysis bullosa	0.003	0.997	0.000
Q80 Congenital ichthyosis	0.003	0.997	0.000
Q89 Other congenital malformations, not elsewhere classified	0.003	0.997	0.000
Q10.0 Congenital ptosis	0.003	0.997	0.000
Q96.8 Other variants of Turner's syndrome	0.003	0.997	0.000
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.003	0.997	0.000
Q96.3 Mosaicism, 45,X/46,XX or XY	0.003	0.997	0.000
Q96.2 Karyotype 46,X with abnormal sex chromosome, except iso (Xq)	0.003	0.997	0.000
Q96.1 Karyotype 46,X iso (Xq)	0.003	0.997	0.000
Q96.0 Karyotype 45,X	0.003	0.997	0.000
Q24.6 Congenital heart block	0.003	0.997	0.000
Q24.4 Congenital subaortic stenosis	0.003	0.997	0.000
Q24.3 Pulmonary infundibular stenosis	0.003	0.997	0.000
Q24.2 Cor triatriatum	0.003	0.997	0.000
Q24.1 Levocardia	0.003	0.997	0.000
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.003	0.997	0.000
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.003	0.997	0.000
Q98.7 Male with sex chromosome mosaicism	0.003	0.997	0.000
Q98.6 Male with structurally abnormal sex chromosome	0.003	0.997	0.000
Q98.5 Karyotype 47,XYY	0.003	0.997	0.000
Q98.3 Other male with 46,XX karyotype	0.003	0.997	0.000
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.003	0.997	0.000
Q98.1 Klinefelter's syndrome, male with more than two X chromosomes	0.003	0.997	0.000
Q98.0 Klinefelter's syndrome karyotype 47,XXY	0.003	0.997	0.000
F20.0 Paranoid schizophrenia	0.003	0.997	0.000
J86.9 Pyothorax without fistula	0.003	0.997	0.000
Q35.8 (Cleft palate, unspecified, bilateral)	0.003	0.997	0.000
Q35.7 Cleft uvula	0.003	0.997	0.000
Q35.6 Cleft palate, medial	0.003	0.997	0.000
Q35.5 Cleft hard palate with cleft soft palate	0.003	0.997	0.000
Q35.4 (Cleft hard palate with cleft soft palate, bilateral)	0.003	0.997	0.000
Q35.3 Cleft soft palate	0.003	0.997	0.000
Q35.2 (Cleft soft palate, bilateral)	0.003	0.997	0.000
Q35.1 Cleft hard palate	0.003	0.997	0.000
Q35.0 (Cleft hard palate, bilateral)	0.003	0.997	0.000
Q26 Congenital malformations of great veins	0.003	0.997	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
M54.39 Sciatica (Site unspecified)	0.000	0.997	0.003
D47.1 Chronic myeloproliferative disease	0.000	0.997	0.003
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.000	0.997	0.003
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.000	0.997	0.003
M96.4 Postsurgical lordosis	0.000	0.997	0.003
M96.3 Postlaminectomy kyphosis	0.000	0.997	0.003
M96.2 Postradiation kyphosis	0.000	0.997	0.003
Q07 Other congenital malformations of nervous system	0.003	0.997	0.000
Q24.0 Dextrocardia	0.003	0.997	0.000
D75.1 Secondary polycythaemia	0.000	0.997	0.003
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.000	0.997	0.003
Q10.7 Congenital malformation of orbit	0.003	0.997	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.003	0.997	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.003	0.997	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.003	0.997	0.000
Q10.3 Other congenital malformations of eyelid	0.003	0.997	0.000
Q10.2 Congenital entropion	0.003	0.997	0.000
Q10.1 Congenital ectropion	0.003	0.997	0.000
I71 Aortic aneurysm and dissection	0.000	0.997	0.003
Q05.4 Unspecified spina bifida with hydrocephalus	0.003	0.997	0.000
K04.5 Chronic apical periodontitis	0.000	0.997	0.003
M96.5 Postradiation scoliosis	0.000	0.997	0.003
Q91.7 Patau's syndrome, unspecified	0.003	0.997	0.000
Q91.6 Trisomy 13, translocation	0.003	0.997	0.000
Q91.5 Trisomy 13, mosaicism (mitotic nondisjunction)	0.003	0.997	0.000
Q91.4 Trisomy 13, meiotic nondisjunction	0.003	0.997	0.000
Q91.3 Edwards' syndrome, unspecified	0.003	0.997	0.000
Q91.2 Trisomy 18, translocation	0.003	0.997	0.000
Q91.1 Trisomy 18, mosaicism (mitotic nondisjunction)	0.003	0.997	0.000
Q91.0 Trisomy 18, meiotic nondisjunction	0.003	0.997	0.000
Q92.9 Trisomy and partial trisomy of autosomes, unspecified	0.003	0.997	0.000
Q92.8 Other specified trisomies and partial trisomies of autosomes	0.003	0.997	0.000
Q92.7 Triploidy and polyploidy	0.003	0.997	0.000
Q92.6 Extra marker chromosomes	0.003	0.997	0.000
Q92.5 Duplications with other complex rearrangements	0.003	0.997	0.000
Q92.4 Duplications seen only at prometaphase	0.003	0.997	0.000
Q92.3 Minor partial trisomy	0.003	0.997	0.000
Q92.2 Major partial trisomy	0.003	0.997	0.000
Q92.1 Whole chromosome trisomy, mosaicism (mitotic nondisjunction)	0.003	0.997	0.000
Q92.0 Whole chromosome trisomy, meiotic nondisjunction	0.003	0.997	0.000
Q93.9 Deletion from autosomes, unspecified	0.003	0.997	0.000
Q93.8 Other deletions from the autosomes	0.003	0.997	0.000
Q93.7 Deletions with other complex rearrangements	0.003	0.997	0.000
Q93.6 Deletions seen only at prometaphase	0.003	0.997	0.000
Q93.5 Other deletions of part of a chromosome	0.003	0.997	0.000
Q93.4 Deletion of short arm of chromosome 5	0.003	0.997	0.000
Q93.3 Deletion of short arm of chromosome 4	0.003	0.997	0.000
Q93.2 Chromosome replaced with ring or dicentric	0.003	0.997	0.000
Q93.1 Whole chromosome monosomy, mosaicism (mitotic nondisjunction)	0.003	0.997	0.000
Q93.0 Whole chromosome monosomy, meiotic nondisjunction	0.003	0.997	0.000
Q95.9 Balanced rearrangement and structural marker, unspecified	0.003	0.997	0.000
Q95.8 Other balanced rearrangements and structural markers	0.003	0.997	0.000
Q95.5 Individuals with autosomal fragile site	0.003	0.997	0.000
Q95.4 Individuals with marker heterochromatin	0.003	0.997	0.000
Q95.3 Balanced sex/autosomal rearrangement in abnormal individual	0.003	0.997	0.000
Q95.2 Balanced autosomal rearrangement in abnormal individual	0.003	0.997	0.000
Q95.1 Chromosome inversion in normal individual	0.003	0.997	0.000
Q95.0 Balanced translocation and insertion in normal individual	0.003	0.997	0.000
Q97.9 Sex chromosome abnormality, female phenotype, unspecified	0.003	0.997	0.000
Q97.8 Other specified sex chromosome abnormalities, female phenotype	0.003	0.997	0.000
Q97.3 Female with 46,XY karyotype	0.003	0.997	0.000
Q97.2 Mosaicism, lines with various numbers of X chromosomes	0.003	0.997	0.000
Q97.1 Female with more than three X chromosomes	0.003	0.997	0.000
Q97.0 Karyotype 47,XXX	0.003	0.997	0.000
N23 Unspecified renal colic	0.003	0.997	0.000
L60.9 Nail disorder, unspecified	0.003	0.997	0.000
Q28 Other congenital malformations of circulatory system	0.003	0.997	0.000
Q82.2 Mastocytosis	0.003	0.997	0.000
Q99.9 Chromosomal abnormality, unspecified	0.003	0.997	0.000
Q99.2 Fragile X chromosome	0.003	0.997	0.000
Q99.1 46,XX true hermaphrodite	0.003	0.997	0.000
Q99.0 Chimera 46,XX/46,XY	0.003	0.997	0.000
Q11.3 Macrophthalmos	0.003	0.997	0.000
Q11.2 Microphthalmos	0.003	0.997	0.000
Q11.1 Other anophthalmos	0.003	0.997	0.000
Q11.0 Cystic eyeball	0.003	0.997	0.000
Q13.9 Congenital malformation of anterior segment of eye, unspecified	0.003	0.997	0.000
Q13.8 Other congenital malformations of anterior segment of eye	0.003	0.997	0.000
Q13.5 Blue sclera	0.003	0.997	0.000
Q13.4 Other congenital corneal malformations	0.003	0.997	0.000
Q13.3 Congenital corneal opacity	0.003	0.997	0.000
Q13.2 Other congenital malformations of iris	0.003	0.997	0.000
Q13.1 Absence of iris	0.003	0.997	0.000
Q13.0 Coloboma of iris	0.003	0.997	0.000
Q16.9 Congenital malformation of ear causing impairment of hearing, unspecified	0.003	0.997	0.000
Q16.5 Congenital malformation of inner ear	0.003	0.997	0.000
Q16.4 Other congenital malformations of middle ear	0.003	0.997	0.000
Q16.3 Congenital malformation of ear ossicles	0.003	0.997	0.000
Q16.2 Absence of eustachian tube	0.003	0.997	0.000
Q16.1 Congenital absence, atresia and stricture of auditory canal (external)	0.003	0.997	0.000
Q16.0 Congenital absence of (ear) auricle	0.003	0.997	0.000
Q99.8 Other specified chromosome abnormalities	0.003	0.997	0.000
Q00.2 Iniencephaly	0.003	0.997	0.000
Q00.1 Craniorachischisis	0.003	0.997	0.000
Q00.0 Anencephaly	0.003	0.997	0.000
Q01.9 Encephalocele, unspecified	0.003	0.997	0.000
Q01.8 Encephalocele of other sites	0.003	0.997	0.000
Q01.2 Occipital encephalocele	0.003	0.997	0.000
Q01.1 Nasofrontal encephalocele	0.003	0.997	0.000
Q01.0 Frontal encephalocele	0.003	0.997	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.003	0.997	0.000
Q03.8 Other congenital hydrocephalus	0.003	0.997	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.003	0.997	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.003	0.997	0.000
Q06.9 Congenital malformation of spinal cord, unspecified	0.003	0.997	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.003	0.997	0.000
Q06.4 Hydromyelia	0.003	0.997	0.000
Q06.3 Other congenital cauda equina malformations	0.003	0.997	0.000
Q06.2 Diastematomyelia	0.003	0.997	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.003	0.997	0.000
Q06.0 Amyelia	0.003	0.997	0.000
Q36.9 Cleft lip, unilateral	0.003	0.997	0.000
Q36.1 Cleft lip, medial	0.003	0.997	0.000
Q36.0 Cleft lip, bilateral	0.003	0.997	0.000
Q54.1 Hypospadias, penile	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations