TreeWAS – Variant ID: rs961253

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.997	0.003	0.000
D12.8 Rectum	0.996	0.004	0.000
D12.5 Sigmoid colon	0.993	0.007	0.000
D12.3 Transverse colon	0.950	0.050	0.000
D12.4 Descending colon	0.909	0.091	0.000
D12.2 Ascending colon	0.907	0.093	0.000
D12.0 Caecum	0.875	0.125	0.000
D12.7 Rectosigmoid junction	0.841	0.159	0.000
D12.6 Colon, unspecified	0.630	0.370	0.000
D12.9 Anus and anal canal	0.613	0.387	0.000
D12.1 Appendix	0.571	0.428	0.000
K63.5 Polyp of colon	0.481	0.519	0.000
O21.0 Mild hyperemesis gravidarum	0.133	0.867	0.000
O21 Excessive vomiting in pregnancy	0.125	0.875	0.000
O21.8 Other vomiting complicating pregnancy	0.107	0.893	0.000
O21.9 Vomiting of pregnancy, unspecified	0.104	0.896	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.101	0.899	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.098	0.902	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.096	0.904	0.000
O24 Diabetes mellitus in pregnancy	0.096	0.904	0.000
K63 Other diseases of intestine	0.096	0.904	0.000
O23 Infections of genito-urinary tract in pregnancy	0.092	0.908	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.088	0.912	0.000
K63.0 Abscess of intestine	0.086	0.914	0.000
O21.2 Late vomiting of pregnancy	0.086	0.914	0.000
K63.3 Ulcer of intestine	0.083	0.917	0.000
K63.2 Fistula of intestine	0.073	0.927	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.073	0.927	0.000
O23.5 Infections of the genital tract in pregnancy	0.071	0.929	0.000
O29 Complications of anaesthesia during pregnancy	0.069	0.931	0.000
O25 Malnutrition in pregnancy	0.069	0.931	0.000
O23.0 Infections of kidney in pregnancy	0.069	0.931	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.069	0.931	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.069	0.931	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.069	0.931	0.000
O22 Venous complications in pregnancy	0.068	0.932	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.066	0.934	0.000
O23.2 Infections of urethra in pregnancy	0.066	0.934	0.000
O23.1 Infections of bladder in pregnancy	0.066	0.934	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.063	0.937	0.000
K63.4 Enteroptosis	0.060	0.940	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.060	0.940	0.000
O28 Abnormal findings on antenatal screening of mother	0.058	0.942	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.050	0.950	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.050	0.950	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.050	0.950	0.000
O29.6 Failed or difficult intubation during pregnancy	0.050	0.950	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.050	0.950	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.050	0.950	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.050	0.950	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.050	0.950	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.050	0.950	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.050	0.950	0.000
K63.9 Disease of intestine, unspecified	0.049	0.951	0.000
O22.9 Venous complication in pregnancy, unspecified	0.049	0.951	0.000
O22.8 Other venous complications in pregnancy	0.049	0.951	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.049	0.951	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.049	0.951	0.000
O22.1 Genital varices in pregnancy	0.049	0.951	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.048	0.952	0.000
O22.4 Haemorrhoids in pregnancy	0.047	0.953	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.042	0.958	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.042	0.958	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.042	0.958	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.042	0.958	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.042	0.958	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.042	0.958	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.041	0.959	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.033	0.967	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.031	0.969	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.029	0.971	0.000
O69.8 Labour and delivery complicated by other cord complications	0.028	0.972	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.023	0.977	0.000
H43.1 Vitreous haemorrhage	0.000	0.978	0.022
O69.1 Labour and delivery complicated by cord around neck, with compression	0.022	0.978	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.021	0.979	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.021	0.979	0.000
O69.3 Labour and delivery complicated by short cord	0.021	0.979	0.000
K63.1 Perforation of intestine (nontraumatic)	0.019	0.980	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.019	0.981	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.019	0.981	0.000
Y84.0 Cardiac catheterisation	0.000	0.984	0.016
K63.8 Other specified diseases of intestine	0.015	0.985	0.000
O20 Haemorrhage in early pregnancy	0.014	0.985	0.001
O26.0 Excessive weight gain in pregnancy	0.014	0.986	0.000
O26.5 Maternal hypotension syndrome	0.013	0.986	0.000
O26.4 Herpes gestationis	0.013	0.986	0.000
O26.1 Low weight gain in pregnancy	0.013	0.986	0.000
H90.5 Sensorineural hearing loss, unspecified	0.000	0.987	0.013
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.013	0.987	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.013	0.987	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.011	0.988	0.000
E83.5 Disorders of calcium metabolism	0.000	0.989	0.011
H90 Conductive and sensorineural hearing loss	0.000	0.989	0.011
O26.9 Pregnancy-related condition, unspecified	0.010	0.990	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.991	0.009
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.991	0.009
Z80.0 Family history of malignant neoplasm of digestive organs	0.009	0.991	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.991	0.009
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.991	0.009
J38.7 Other diseases of larynx	0.000	0.991	0.009
J38.3 Other diseases of vocal cords	0.000	0.991	0.009
O26.2 Pregnancy care of habitual aborter	0.008	0.991	0.000
H90.3 Sensorineural hearing loss, bilateral	0.000	0.991	0.008
H90.2 Conductive hearing loss, unspecified	0.000	0.991	0.008
J38.2 Nodules of vocal cords	0.000	0.992	0.008
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.992	0.008
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.007	0.993	0.000
O20.8 Other haemorrhage in early pregnancy	0.007	0.993	0.001
O26.8 Other specified pregnancy-related conditions	0.007	0.993	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.993	0.007
H90.0 Conductive hearing loss, bilateral	0.000	0.993	0.007
J38.4 Oedema of larynx	0.000	0.995	0.005
D21 Other benign neoplasms of connective and other soft tissue	0.005	0.995	0.000
J38.1 Polyp of vocal cord and larynx	0.000	0.995	0.005
D21.5 Connective and other soft tissue of pelvis	0.005	0.995	0.000
D21.0 Connective and other soft tissue of head, face and neck	0.005	0.995	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
K59.3 Megacolon, not elsewhere classified	0.000	0.995	0.005
T78.2 Anaphylactic shock, unspecified	0.005	0.995	0.000
O20.0 Threatened abortion	0.004	0.995	0.000
J38.6 Stenosis of larynx	0.000	0.996	0.004
H43 Disorders of vitreous body	0.000	0.996	0.004
D21.6 Connective and other soft tissue of trunk, unspecified	0.004	0.996	0.000
D21.4 Connective and other soft tissue of abdomen	0.004	0.996	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.004	0.996	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.004	0.996	0.000
Z98.0 Intestinal bypass and anastomosis status	0.004	0.996	0.000
Q66 Congenital deformities of feet	0.004	0.996	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
D21.9 Connective and other soft tissue, unspecified	0.004	0.996	0.000
H71 Cholesteatoma of middle ear	0.000	0.996	0.004
D21.3 Connective and other soft tissue of thorax	0.004	0.996	0.000
Q66.7 Pes cavus	0.004	0.996	0.000
Q79.6 Ehlers-Danlos syndrome	0.004	0.996	0.000
Q66.0 Talipes equinovarus	0.004	0.996	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
J38.5 Laryngeal spasm	0.000	0.996	0.003
O12.1 Gestational proteinuria	0.003	0.996	0.000
Q66.2 Metatarsus varus	0.003	0.996	0.000
N73.9 Female pelvic inflammatory disease, unspecified	0.000	0.997	0.003
Chapter XV Pregnancy, childbirth and the puerperium	0.003	0.997	0.000
Y57.5 X-ray contrast media	0.003	0.997	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.003	0.997	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.997	0.003
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.997	0.000
H43.0 Vitreous prolapse	0.000	0.997	0.003
Q66.8 Other congenital deformities of feet	0.003	0.997	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
I42.2 Other hypertrophic cardiomyopathy	0.000	0.997	0.003
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
I42.9 Cardiomyopathy, unspecified	0.000	0.997	0.003
H43.2 Crystalline deposits in vitreous body	0.000	0.997	0.003
I42.0 Dilated cardiomyopathy	0.000	0.997	0.003
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.003	0.997	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.003	0.997	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.003	0.997	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.997	0.003
Q66.5 Congenital pes planus	0.003	0.997	0.000
Q66.4 Talipes calcaneovalgus	0.003	0.997	0.000
Q66.1 Talipes calcaneovarus	0.003	0.997	0.000
H43.8 Other disorders of vitreous body	0.000	0.997	0.003
Q77.4 Achondroplasia	0.003	0.997	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.003	0.997	0.000
K90.9 Intestinal malabsorption, unspecified	0.003	0.997	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.003	0.997	0.000
W10.8 Other specified place	0.003	0.997	0.000
A49.8 Other bacterial infections of unspecified site	0.000	0.997	0.003
I42 Cardiomyopathy	0.000	0.997	0.003
Q66.6 Other congenital valgus deformities of feet	0.003	0.997	0.000
J38.0 Paralysis of vocal cords and larynx	0.000	0.997	0.003
Q66.9 Congenital deformity of feet, unspecified	0.003	0.997	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.003	0.997	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.003	0.997	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.003	0.997	0.000
O12.2 Gestational oedema with proteinuria	0.003	0.997	0.000
W10.4 Street and highway	0.003	0.997	0.000
Q78 Other osteochondrodysplasias	0.003	0.997	0.000
Q66.3 Other congenital varus deformities of feet	0.003	0.997	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O97 Death from sequelae of direct obstetric causes	0.003	0.997	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.003	0.997	0.000
O95 Obstetric death of unspecified cause	0.003	0.997	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.003	0.997	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.003	0.997	0.000
H43.9 Disorder of vitreous body, unspecified	0.000	0.997	0.002
O20.9 Haemorrhage in early pregnancy, unspecified	0.001	0.997	0.001
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.002	0.997	0.000
Q79.5 Other congenital malformations of abdominal wall	0.002	0.997	0.000
Q79.4 Prune belly syndrome	0.002	0.997	0.000
Q79.3 Gastroschisis	0.002	0.997	0.000
Q79.2 Exomphalos	0.002	0.997	0.000
Q79.1 Other congenital malformations of diaphragm	0.002	0.997	0.000
Q79.0 Congenital diaphragmatic hernia	0.002	0.997	0.000
Q75 Other congenital malformations of skull and face bones	0.003	0.997	0.000
Q73 Reduction defects of unspecified limb	0.003	0.997	0.000
Q72 Reduction defects of lower limb	0.003	0.997	0.000
Q71 Reduction defects of upper limb	0.003	0.997	0.000
Q70 Syndactyly	0.003	0.997	0.000
Q69 Polydactyly	0.003	0.997	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.003	0.997	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
Q67.6 Pectus excavatum	0.002	0.997	0.000
Q65 Congenital deformities of hip	0.003	0.997	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.003	0.997	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.002	0.997	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.003	0.997	0.000
D04.5 Skin of trunk	0.003	0.997	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.997	0.000
I42.8 Other cardiomyopathies	0.000	0.997	0.002
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.002	0.997	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.002	0.998	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.002	0.998	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.002	0.998	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.002	0.998	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.002	0.998	0.000
Q77.6 Chondroectodermal dysplasia	0.002	0.998	0.000
Q77.5 Diastrophic dysplasia	0.002	0.998	0.000
Q77.3 Chondrodysplasia punctata	0.002	0.998	0.000
Q77.2 Short rib syndrome	0.002	0.998	0.000
Q77.1 Thanatophoric short stature	0.002	0.998	0.000
Q77.0 Achondrogenesis	0.002	0.998	0.000
O15 Eclampsia	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Q67.8 Other congenital deformities of chest	0.002	0.998	0.000
Q67.7 Pectus carinatum	0.002	0.998	0.000
Q67.3 Plagiocephaly	0.002	0.998	0.000
Q67.2 Dolichocephaly	0.002	0.998	0.000
Q67.1 Compression facies	0.002	0.998	0.000
Q67.0 Facial asymmetry	0.002	0.998	0.000
L81.4 Other melanin hyperpigmentation	0.000	0.998	0.002
O86.0 Infection of obstetric surgical wound	0.002	0.998	0.000
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.002	0.998	0.000
Q78.0 Osteogenesis imperfecta	0.002	0.998	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.002	0.998	0.000
I42.5 Other restrictive cardiomyopathy	0.000	0.998	0.002
I42.4 Endocardial fibroelastosis	0.000	0.998	0.002
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.998	0.002
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.002	0.998	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.000	0.998	0.002
Q67.5 Congenital deformity of spine	0.002	0.998	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.998	0.002
Q78.9 Osteochondrodysplasia, unspecified	0.002	0.998	0.000
Q78.8 Other specified osteochondrodysplasias	0.002	0.998	0.000
Q78.6 Multiple congenital exostoses	0.002	0.998	0.000
Q78.5 Metaphyseal dysplasia	0.002	0.998	0.000
Q78.4 Enchondromatosis	0.002	0.998	0.000
Q78.3 Progressive diaphyseal dysplasia	0.002	0.998	0.000
Q78.2 Osteopetrosis	0.002	0.998	0.000
Q78.1 Polyostotic fibrous dysplasia	0.002	0.998	0.000
D23.4 Skin of scalp and neck	0.000	0.998	0.002
Y57.9 Drug or medicament, unspecified	0.002	0.998	0.000
M07.3 Other psoriatic arthropathies	0.002	0.998	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.002	0.998	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.998	0.002
O96.9 Death from unspecified obstetric cause	0.002	0.998	0.000
O96.1 Death from indirect obstetric cause	0.002	0.998	0.000
O96.0 Death from direct obstetric cause	0.002	0.998	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.002	0.998	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.002	0.998	0.000
O97.0 Death from sequelae of direct obstetric cause	0.002	0.998	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.002	0.998	0.000
A49.9 Bacterial infection, unspecified	0.000	0.998	0.002
Q68.8 Other specified congenital musculoskeletal deformities	0.002	0.998	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.002	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.002	0.998	0.000
Q68.3 Congenital bowing of femur	0.002	0.998	0.000
Q68.2 Congenital deformity of knee	0.002	0.998	0.000
Q68.1 Congenital deformity of hand	0.002	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.002	0.998	0.000
Q69.9 Polydactyly, unspecified	0.002	0.998	0.000
Q69.2 Accessory toe(s)	0.002	0.998	0.000
Q69.1 Accessory thumb(s)	0.002	0.998	0.000
Q69.0 Accessory finger(s)	0.002	0.998	0.000
Q70.9 Syndactyly, unspecified	0.002	0.998	0.000
Q70.4 Polysyndactyly	0.002	0.998	0.000
Q70.3 Webbed toes	0.002	0.998	0.000
Q70.2 Fused toes	0.002	0.998	0.000
Q70.1 Webbed fingers	0.002	0.998	0.000
Q70.0 Fused fingers	0.002	0.998	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.002	0.998	0.000
Q71.8 Other reduction defects of upper limb(s)	0.002	0.998	0.000
Q71.6 Lobster-claw hand	0.002	0.998	0.000
Q71.5 Longitudinal reduction defect of ulna	0.002	0.998	0.000
Q71.4 Longitudinal reduction defect of radius	0.002	0.998	0.000
Q71.3 Congenital absence of hand and finger(s)	0.002	0.998	0.000
Q71.2 Congenital absence of both forearm and hand	0.002	0.998	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.002	0.998	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.002	0.998	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.002	0.998	0.000
Q72.8 Other reduction defects of lower limb(s)	0.002	0.998	0.000
Q72.7 Split foot	0.002	0.998	0.000
Q72.6 Longitudinal reduction defect of fibula	0.002	0.998	0.000
Q72.5 Longitudinal reduction defect of tibia	0.002	0.998	0.000
Q72.4 Longitudinal reduction defect of femur	0.002	0.998	0.000
Q72.3 Congenital absence of foot and toe(s)	0.002	0.998	0.000
Q72.2 Congenital absence of both lower leg and foot	0.002	0.998	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.002	0.998	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.002	0.998	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.002	0.998	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.002	0.998	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.002	0.998	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.002	0.998	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.002	0.998	0.000
Q75.5 Oculomandibular dysostosis	0.002	0.998	0.000
Q75.4 Mandibulofacial dysostosis	0.002	0.998	0.000
Q75.3 Macrocephaly	0.002	0.998	0.000
Q75.2 Hypertelorism	0.002	0.998	0.000
Q75.1 Craniofacial dysostosis	0.002	0.998	0.000
Q75.0 Craniosynostosis	0.002	0.998	0.000
O16 Unspecified maternal hypertension	0.002	0.998	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.002	0.998	0.000
W10 Fall on and from stairs and steps	0.002	0.998	0.000
Q65.9 Congenital deformity of hip, unspecified	0.002	0.998	0.000
Q65.6 Unstable hip	0.002	0.998	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.002	0.998	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.002	0.998	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.002	0.998	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.002	0.998	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.002	0.998	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.002	0.998	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
R06.2 Wheezing	0.000	0.998	0.002
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
J99.8 Respiratory disorders in other diseases classified elsewhere	0.000	0.998	0.002
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Z75.5 Holiday relief care	0.000	0.998	0.002
O15.9 Eclampsia, unspecified as to time period	0.002	0.998	0.000
O15.2 Eclampsia in the puerperium	0.002	0.998	0.000
O15.1 Eclampsia in labour	0.002	0.998	0.000
O15.0 Eclampsia in pregnancy	0.002	0.998	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Q76.0 Spina bifida occulta	0.002	0.998	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.002	0.998	0.000
Q76.8 Other congenital malformations of bony thorax	0.002	0.998	0.000
Q76.7 Congenital malformation of sternum	0.002	0.998	0.000
Q76.6 Other congenital malformations of ribs	0.002	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.002	0.998	0.000
Q76.2 Congenital spondylolisthesis	0.002	0.998	0.000
H90-H95 Other disorders of ear	0.000	0.998	0.002
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.000	0.998	0.002
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Q76.5 Cervical rib	0.002	0.998	0.000
C18.4 Transverse colon	0.002	0.998	0.000
G44.2 Tension-type headache	0.000	0.998	0.002
Q74.9 Unspecified congenital malformation of limb(s)	0.002	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.002	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.002	0.998	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.998	0.002
M07.34 Other psoriatic arthropathies (Hand)	0.002	0.998	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.000	0.998	0.002
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Q65.8 Other congenital deformities of hip	0.002	0.998	0.000
E83 Disorders of mineral metabolism	0.000	0.998	0.002
Z98 Other postsurgical states	0.002	0.998	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.002	0.998	0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.000	0.998	0.002
Q74.1 Congenital malformation of knee	0.002	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.6 Other diagnostic agents	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
C18.7 Sigmoid colon	0.002	0.998	0.000
M07.38 Other psoriatic arthropathies (Other)	0.002	0.998	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.002	0.998	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.002	0.998	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.002	0.998	0.000
O85-O92 Complications predominantly related to the puerperium	0.002	0.998	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.998	0.000
A49 Bacterial infection of unspecified site	0.000	0.998	0.002
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.002	0.998	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.000	0.998	0.002
D68.0 Von Willebrand's disease	0.000	0.998	0.002
I42.6 Alcoholic cardiomyopathy	0.000	0.998	0.002
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.002	0.998	0.000
W10.9 Unspecified place	0.002	0.998	0.000
W10.5 Trade and service area	0.002	0.998	0.000
W10.2 School, other institution and public administrative area	0.002	0.998	0.000
W10.0 Home	0.002	0.998	0.000
W10.7 Farm	0.002	0.998	0.000
W10.1 Residential institution	0.002	0.998	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O86 Other puerperal infections	0.002	0.998	0.000
B44.1 Other pulmonary aspergillosis	0.000	0.998	0.002
W10.6 Industrial and construction area	0.002	0.998	0.000
Z50.2 Alcohol rehabilitation	0.002	0.998	0.000
Z98.2 Presence of cerebrospinal fluid drainage device	0.002	0.998	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.000	0.998	0.002
C84.5 Other and unspecified T-cell lymphomas	0.000	0.998	0.002
H95.8 Other postprocedural disorders of ear and mastoid process	0.000	0.998	0.002
O12.0 Gestational oedema	0.001	0.998	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.998	0.002
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.998	0.002
A49.2 Haemophilus influenzae infection, unspecified	0.000	0.998	0.002
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
D33.2 Brain, unspecified	0.000	0.998	0.002
M96.8 Other postprocedural musculoskeletal disorders	0.002	0.998	0.000
U51.1 Previously admitted to a psychiatric hospital of the provider	0.000	0.998	0.002
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.998	0.002
E83.8 Other disorders of mineral metabolism	0.000	0.998	0.002
E83.2 Disorders of zinc metabolism	0.000	0.998	0.002
E83.0 Disorders of copper metabolism	0.000	0.998	0.002
G83.4 Cauda equina syndrome	0.000	0.998	0.002
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.000	0.998	0.002
T82.1 Mechanical complication of cardiac electronic device	0.000	0.998	0.002
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.002	0.998	0.000
A87.9 Viral meningitis, unspecified	0.002	0.998	0.000
C84.0 Mycosis fungoides	0.000	0.998	0.002
N48.6 Balanitis xerotica obliterans	0.002	0.998	0.000
W10.3 Sports and athletics area	0.001	0.998	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.998	0.002
N32.9 Bladder disorder, unspecified	0.000	0.998	0.002
H43-H45 Disorders of vitreous body and globe	0.000	0.998	0.002
S42.10 Fracture of scapula (closed)	0.002	0.998	0.000
A49.3 Mycoplasma infection, unspecified	0.000	0.998	0.001
O88 Obstetric embolism	0.001	0.998	0.000
V48.4 Person injured while boarding or alighting	0.002	0.998	0.000
Z98.8 Other specified postsurgical states	0.002	0.998	0.000
O80-O84 Delivery	0.002	0.998	0.000
W10.08 Fall on and from stairs and steps; Home; While engaged in other specified activities	0.001	0.998	0.000
W10.04 Fall on and from stairs and steps; Home; While resting, sleeping, eating or engaging in other vital activities	0.001	0.998	0.000
W10.03 Fall on and from stairs and steps; Home; While engaged in other types of work	0.001	0.998	0.000
W10.29 Fall on and from stairs and steps; School, other institution and public administrative area; During unspecified activity	0.001	0.998	0.000
W10.59 Fall on and from stairs and steps; Trade and service area; During unspecified activity	0.001	0.998	0.000
W10.92 Fall on and from stairs and steps; Unspecified place; While working for income	0.001	0.998	0.000
W10.90 Fall on and from stairs and steps; Unspecified place; While engaged in sports activity	0.001	0.998	0.000
C84.4 Peripheral T-cell lymphoma	0.000	0.998	0.002
Z98.1 Arthrodesis status	0.002	0.998	0.000
D68 Other coagulation defects	0.000	0.998	0.002
O89 Complications of anaesthesia during the puerperium	0.001	0.998	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.002	0.998	0.000
C18.3 Hepatic flexure	0.002	0.998	0.000
D68.4 Acquired coagulation factor deficiency	0.000	0.998	0.001
O86.3 Other genito-urinary tract infections following delivery	0.001	0.998	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.001	0.998	0.000
M47.89 Other spondylosis (Site unspecified)	0.002	0.998	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.998	0.002
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.998	0.002
S49.8 Other specified injuries of shoulder and upper arm	0.001	0.998	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.001	0.998	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.001	0.998	0.000
O91 Infections of breast associated with childbirth	0.001	0.998	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.000	0.998	0.001
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
O64.1 Obstructed labour due to breech presentation	0.002	0.998	0.000
C16.9 Stomach, unspecified	0.002	0.998	0.000
D68.8 Other specified coagulation defects	0.000	0.998	0.002
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.001	0.998	0.000
O86.8 Other specified puerperal infections	0.001	0.998	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.001	0.998	0.000
D23.3 Skin of other and unspecified parts of face	0.000	0.998	0.002
D68.5 Primary Thrombophilia	0.000	0.998	0.001
O86.2 Urinary tract infection following delivery	0.001	0.998	0.000
H95.1 Other disorders following mastoidectomy	0.000	0.999	0.001
I86.4 Gastric varices	0.000	0.999	0.001
O81 Single delivery by forceps and vacuum extractor	0.001	0.999	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.000	0.999	0.001
H20.0 Acute and subacute iridocyclitis	0.000	0.999	0.001
O81.4 Vacuum extractor delivery	0.001	0.999	0.000
O88.8 Other obstetric embolism	0.001	0.999	0.000
O88.3 Obstetric pyaemic and septic embolism	0.001	0.999	0.000
O88.2 Obstetric blood-clot embolism	0.001	0.999	0.000
O88.1 Amniotic fluid embolism	0.001	0.999	0.000
O88.0 Obstetric air embolism	0.001	0.999	0.000
I10 Essential (primary) hypertension	0.000	0.999	0.001
O64 Obstructed labour due to malposition and malpresentation of foetus	0.001	0.999	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.001	0.999	0.000
R07.0 Pain in throat	0.000	0.999	0.001
O83 Other assisted single delivery	0.001	0.999	0.000
C45.9 Mesothelioma, unspecified	0.000	0.999	0.001
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.001	0.999	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.001	0.999	0.000
O89.6 Failed or difficult intubation during the puerperium	0.001	0.999	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.001	0.999	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations