TreeWAS – Variant ID: rs964611

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.102	0.898	0.000
I69 Sequelae of cerebrovascular disease	0.074	0.926	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.070	0.930	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.053	0.947	0.000
I60-I69 Cerebrovascular diseases	0.051	0.949	0.000
I62 Other nontraumatic intracranial haemorrhage	0.049	0.951	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.046	0.954	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.044	0.956	0.000
I63 Cerebral infarction	0.042	0.958	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.042	0.958	0.000
I69.3 Sequelae of cerebral infarction	0.041	0.959	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.040	0.960	0.000
D70 Agranulocytosis	0.000	0.960	0.040
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.039	0.961	0.000
I63.8 Other cerebral infarction	0.038	0.962	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.037	0.963	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.037	0.963	0.000
I67 Other cerebrovascular diseases	0.037	0.963	0.000
C18 Malignant neoplasm of colon	0.000	0.964	0.036
I61 Intracerebral haemorrhage	0.036	0.964	0.000
I60 Subarachnoid haemorrhage	0.035	0.965	0.000
I62.1 Nontraumatic extradural haemorrhage	0.035	0.965	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.034	0.966	0.000
I67.9 Cerebrovascular disease, unspecified	0.034	0.966	0.000
C18.4 Transverse colon	0.000	0.966	0.034
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.034	0.966	0.000
C18.7 Sigmoid colon	0.000	0.967	0.033
C18.2 Ascending colon	0.000	0.967	0.033
I66.0 Occlusion and stenosis of middle cerebral artery	0.032	0.968	0.000
C18.9 Colon, unspecified	0.000	0.968	0.032
C18.1 Appendix	0.000	0.969	0.031
C18.0 Caecum	0.000	0.969	0.031
C18.3 Hepatic flexure	0.000	0.969	0.031
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.031	0.969	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.031	0.969	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.031	0.969	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.030	0.969	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.030	0.970	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.030	0.970	0.000
I65.1 Occlusion and stenosis of basilar artery	0.030	0.970	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.029	0.971	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.029	0.971	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.029	0.971	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.029	0.971	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.029	0.971	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.029	0.971	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.029	0.971	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.029	0.971	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.029	0.971	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.028	0.972	0.000
I60.8 Other subarachnoid haemorrhage	0.028	0.972	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.027	0.972	0.000
C18.5 Splenic flexure	0.000	0.973	0.027
I67.8 Other specified cerebrovascular diseases	0.027	0.973	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.027	0.973	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.027	0.973	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.027	0.973	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.027	0.973	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.027	0.973	0.000
I68.0 Cerebral amyloid angiopathy	0.027	0.973	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.026	0.973	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.026	0.973	0.000
I67.5 Moyamoya disease	0.026	0.973	0.000
I67.4 Hypertensive encephalopathy	0.026	0.973	0.000
I67.3 Progressive vascular leukoencephalopathy	0.026	0.973	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.026	0.974	0.000
C18.8 Overlapping lesion of colon	0.000	0.974	0.026
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.026	0.974	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.026	0.974	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.026	0.974	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.026	0.974	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.025	0.975	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.025	0.975	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.024	0.975	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.024	0.976	0.000
I61.8 Other intracerebral haemorrhage	0.023	0.977	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.023	0.977	0.000
I67.1 Cerebral aneurysm, nonruptured	0.022	0.978	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.022	0.978	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.020	0.980	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.016	0.984	0.000
C18.6 Descending colon	0.000	0.984	0.016
I63.9 Cerebral infarction, unspecified	0.016	0.984	0.000
D18.0 Haemangioma, any site	0.000	0.985	0.015
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.985	0.015
I64 Stroke, not specified as haemorrhage or infarction	0.014	0.986	0.000
S82.60 Fracture of lateral malleolus (closed)	0.014	0.986	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.013	0.987	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.987	0.013
Z50.5 Speech therapy	0.012	0.988	0.000
I67.2 Cerebral atherosclerosis	0.011	0.988	0.000
Z50.4 Psychotherapy, not elsewhere classified	0.012	0.988	0.000
Z50.8 Care involving use of rehabilitation procedures	0.011	0.989	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.011	0.989	0.000
Z50 Care involving use of rehabilitation procedures	0.011	0.989	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.011	0.989	0.000
D72 Other disorders of white blood cells	0.000	0.989	0.011
M21.1 Varus deformity, not elsewhere classified	0.010	0.990	0.000
D74 Methaemoglobinaemia	0.000	0.990	0.010
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.990	0.010
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.990	0.010
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.991	0.009
I65.2 Occlusion and stenosis of carotid artery	0.009	0.991	0.000
F03 Unspecified dementia	0.009	0.991	0.000
D72.1 Eosinophilia	0.000	0.991	0.009
M21 Other acquired deformities of limbs	0.009	0.991	0.000
M21.2 Flexion deformity	0.009	0.991	0.000
D51 Vitamin B12 deficiency anaemia	0.000	0.992	0.008
S82.6 Fracture of lateral malleolus	0.008	0.992	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.008	0.992	0.000
Z50.6 Orthoptic training	0.008	0.992	0.000
Z50.3 Drug rehabilitation	0.008	0.992	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.008	0.992	0.000
M21.3 Wrist or foot drop (acquired)	0.008	0.992	0.000
D72.9 Disorder of white blood cells, unspecified	0.000	0.992	0.008
D72.0 Genetic anomalies of leukocytes	0.000	0.992	0.008
D75 Other diseases of blood and blood-forming organs	0.000	0.992	0.008
M81.98 Osteoporosis, unspecified (Other)	0.008	0.992	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.008	0.992	0.000
M21.27 Flexion deformity (Ankle and foot)	0.008	0.992	0.000
D72.8 Other specified disorders of white blood cells	0.000	0.992	0.008
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.008	0.992	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.007	0.992	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.007	0.992	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.007	0.992	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.007	0.992	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.007	0.992	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.007	0.992	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.007	0.992	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.007	0.992	0.000
M21.9 Acquired deformity of limb, unspecified	0.007	0.993	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.007	0.993	0.000
D74.9 Methaemoglobinaemia, unspecified	0.000	0.993	0.007
D74.8 Other methaemoglobinaemias	0.000	0.993	0.007
D74.0 Congenital methaemoglobinaemia	0.000	0.993	0.007
M21.24 Flexion deformity (Hand)	0.007	0.993	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.000	0.993	0.007
D76.1 Haemophagocytic lymphohistiocytosis	0.000	0.993	0.007
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.000	0.993	0.007
M21.8 Other specified acquired deformities of limbs	0.007	0.993	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.007	0.993	0.000
D76.3 Other histiocytosis syndromes	0.000	0.993	0.007
D75.2 Essential thrombocytosis	0.000	0.993	0.007
M21.7 Unequal limb length (acquired)	0.007	0.993	0.000
Z50.1 Other physical therapy	0.007	0.993	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.007	0.993	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.007	0.993	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.994	0.006
M21.29 Flexion deformity (Site unspecified)	0.006	0.994	0.000
M21.28 Flexion deformity (Other)	0.006	0.994	0.000
M21.23 Flexion deformity (Forearm)	0.006	0.994	0.000
M21.22 Flexion deformity (Upper arm)	0.006	0.994	0.000
M21.21 Flexion deformity (Shoulder region)	0.006	0.994	0.000
M21.20 Flexion deformity (Multiple sites)	0.006	0.994	0.000
M21.6 Other acquired deformities of ankle and foot	0.006	0.994	0.000
M81.9 Osteoporosis, unspecified	0.006	0.994	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.006	0.994	0.000
D50-D53 Nutritional anaemias	0.000	0.994	0.006
S82.61 Fracture of lateral malleolus (open)	0.006	0.994	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.994	0.006
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.994	0.006
D51.2 Transcobalamin II deficiency	0.000	0.994	0.006
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.994	0.006
D68 Other coagulation defects	0.000	0.994	0.006
M21.0 Valgus deformity, not elsewhere classified	0.006	0.994	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.006	0.994	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.006	0.994	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.006	0.994	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.006	0.994	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.006	0.994	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.006	0.994	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.006	0.994	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.006	0.994	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.006	0.994	0.000
M21.26 Flexion deformity (Lower leg)	0.006	0.994	0.000
D18 Haemangioma and lymphangioma, any site	0.000	0.994	0.006
D68.0 Von Willebrand's disease	0.000	0.994	0.006
D75.1 Secondary polycythaemia	0.000	0.994	0.006
D68.8 Other specified coagulation defects	0.000	0.994	0.006
D68.6 Other Thrombophilia	0.000	0.994	0.006
M81.90 Osteoporosis, unspecified (Multiple sites)	0.006	0.994	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.006	0.994	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.005	0.994	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.005	0.994	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.005	0.994	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.005	0.994	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.005	0.994	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.005	0.994	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.005	0.994	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.005	0.994	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.005	0.994	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.005	0.994	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.994	0.005
M21.76 Unequal limb length (acquired) (Lower leg)	0.005	0.995	0.000
M21.4 Flat foot [pes planus] (acquired)	0.005	0.995	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.005	0.995	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.005	0.995	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.005	0.995	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.005	0.995	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.005	0.995	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.005	0.995	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.005	0.995	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.005	0.995	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.005	0.995	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.005	0.995	0.000
D75.0 Familial erythrocytosis	0.000	0.995	0.005
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.005	0.995	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.005	0.995	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.005	0.995	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.005	0.995	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.005	0.995	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.005	0.995	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.005	0.995	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.005	0.995	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.005	0.995	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.005	0.995	0.000
M21.78 Unequal limb length (acquired)-Other	0.005	0.995	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.005	0.995	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.005	0.995	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.005	0.995	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.005	0.995	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.005	0.995	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.005	0.995	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.995	0.005
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.995	0.005
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.995	0.005
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.005	0.995	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.005	0.995	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.005	0.995	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.005	0.995	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.005	0.995	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.005	0.995	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.005	0.995	0.000
Z50.2 Alcohol rehabilitation	0.005	0.995	0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.005	0.995	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.005	0.995	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.005	0.995	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.005	0.995	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.005	0.995	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.005	0.995	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.005	0.995	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.005	0.995	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.005	0.995	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.005	0.995	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.005	0.995	0.000
D53 Other nutritional anaemias	0.000	0.995	0.005
M81.94 Osteoporosis, unspecified (Hand)	0.005	0.995	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.005	0.995	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.005	0.995	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.005	0.995	0.000
C84.4 Peripheral T-cell lymphoma	0.005	0.995	0.000
D68.1 Hereditary factor XI deficiency	0.000	0.995	0.005
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.005	0.995	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.005	0.995	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.005	0.995	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.005	0.995	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.005	0.995	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.005	0.995	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.005	0.995	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.005	0.995	0.000
D68.5 Primary Thrombophilia	0.000	0.995	0.005
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.005	0.995	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.995	0.005
L91.8 Other hypertrophic disorders of skin	0.005	0.995	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.005	0.995	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.004	0.995	0.000
D55-D59 Haemolytic anaemias	0.000	0.995	0.004
N35.9 Urethral stricture, unspecified	0.000	0.995	0.005
S82 Fracture of lower leg, including ankle	0.004	0.996	0.000
S82.10 Fracture of upper end of tibia (closed)	0.004	0.996	0.000
S82.1 Fracture of upper end of tibia	0.004	0.996	0.000
D80-D89 Certain disorders involving the immune mechanism	0.000	0.996	0.004
D18.1 Lymphangioma, any site	0.000	0.996	0.004
O04.9 Complete or unspecified, without complication	0.000	0.996	0.004
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.004	0.996	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.004	0.996	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.004	0.996	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.004	0.996	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.004	0.996	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.004	0.996	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.004	0.996	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.004	0.996	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.004	0.996	0.000
D52 Folate deficiency anaemia	0.000	0.996	0.004
D68.4 Acquired coagulation factor deficiency	0.000	0.996	0.004
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.996	0.004
S82.4 Fracture of fibula alone	0.004	0.996	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.004	0.996	0.000
D67 Hereditary factor IX deficiency	0.000	0.996	0.004
R25.2 Cramp and spasm	0.004	0.996	0.000
D73 Diseases of spleen	0.000	0.996	0.004
D53.9 Nutritional anaemia, unspecified	0.000	0.996	0.004
I71.0 Dissection of aorta [any part]	0.004	0.996	0.000
C84.5 Other and unspecified T-cell lymphomas	0.004	0.996	0.000
D53.8 Other specified nutritional anaemias	0.000	0.996	0.004
D53.2 Scorbutic anaemia	0.000	0.996	0.004
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.000	0.996	0.004
D53.0 Protein deficiency anaemia	0.000	0.996	0.004
S82.9 Fracture of lower leg, part unspecified	0.004	0.996	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.004	0.996	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.996	0.004
S82.40 Fracture of fibula alone (closed)	0.004	0.996	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.004	0.996	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.996	0.003
M05 Seropositive rheumatoid arthritis	0.004	0.996	0.000
H52.1 Myopia	0.000	0.996	0.004
F00-F09 Organic, including symptomatic, mental disorders	0.004	0.996	0.000
S82.7 Multiple fractures of lower leg	0.003	0.996	0.000
D57 Sickle-cell disorders	0.000	0.996	0.003
D55 Anaemia due to enzyme disorders	0.000	0.996	0.003
Y45.1 Salicylates	0.004	0.996	0.000
D56 Thalassaemia	0.000	0.996	0.003
D68.9 Coagulation defect, unspecified	0.000	0.997	0.003
D60-D64 Aplastic and other anaemias	0.000	0.997	0.003
S82.5 Fracture of medial malleolus	0.003	0.997	0.000
G81.9 Hemiplegia, unspecified	0.003	0.997	0.000
D59 Acquired haemolytic anaemia	0.000	0.997	0.003
M47.80 Other spondylosis (Multiple sites in spine)	0.003	0.997	0.000
S82.11 Fracture of upper end of tibia (open)	0.003	0.997	0.000
Y45.0 Opioids and related analgesics	0.003	0.997	0.000
D83 Common variable immunodeficiency	0.000	0.997	0.003
D82 Immunodeficiency associated with other major defects	0.000	0.997	0.003
D81 Combined immunodeficiencies	0.000	0.997	0.003
D58 Other hereditary haemolytic anaemias	0.000	0.997	0.003
Q51.3 Bicornate uterus	0.003	0.997	0.000
D86 Sarcoidosis	0.000	0.997	0.003
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
S82.90 Fracture of lower leg, part unspecified (closed)	0.003	0.997	0.000
D52.8 Other folate deficiency anaemias	0.000	0.997	0.003
D52.1 Drug-induced folate deficiency anaemia	0.000	0.997	0.003
D52.0 Dietary folate deficiency anaemia	0.000	0.997	0.003
D84 Other immunodeficiencies	0.000	0.997	0.003
I74.5 Embolism and thrombosis of iliac artery	0.003	0.997	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.003	0.997	0.000
Y45.5 4-Aminophenol derivatives	0.003	0.997	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.997	0.003
S82.41 Fracture of fibula alone (open)	0.003	0.997	0.000
C84.0 Mycosis fungoides	0.003	0.997	0.000
M81 Osteoporosis without pathological fracture	0.003	0.997	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.003	0.997	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.997	0.003
D86.9 Sarcoidosis, unspecified	0.000	0.997	0.003
D73.9 Disease of spleen, unspecified	0.000	0.997	0.003
D73.2 Chronic congestive splenomegaly	0.000	0.997	0.003
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.002	0.997	0.001
I84.1 Internal haemorrhoids with other complications	0.000	0.997	0.003
F05 Delirium, not induced by alcohol and other psychoactive substances	0.003	0.997	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.003	0.997	0.000
D73.8 Other diseases of spleen	0.000	0.997	0.003
Y45.4 Antirheumatics	0.003	0.997	0.000
Y45.2 Propionic acid derivatives	0.003	0.997	0.000
S82.70 Multiple fractures of lower leg (closed)	0.003	0.997	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.000	0.997	0.003
C84.9 Mature T/NK-cell lymphoma, unspecified	0.003	0.997	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.003	0.997	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.003	0.997	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.003	0.997	0.000
C84.3 Lymphoepithelioid lymphoma	0.003	0.997	0.000
C84.2 T-zone lymphoma	0.003	0.997	0.000
C84.1 Sezary's diease	0.003	0.997	0.000
G90.2 Horner's syndrome	0.000	0.997	0.003
M05.8 Other seropositive rheumatoid arthritis	0.003	0.997	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.003	0.997	0.000
M05.2 Rheumatoid vasculitis	0.003	0.997	0.000
M05.1 Rheumatoid lung disease	0.003	0.997	0.000
M05.0 Felty's syndrome	0.003	0.997	0.000
F02 Dementia in other diseases classified elsewhere	0.003	0.997	0.000
F01 Vascular dementia	0.003	0.997	0.000
D73.3 Abscess of spleen	0.000	0.997	0.003
D86.8 Sarcoidosis of other and combined sites	0.000	0.997	0.003
N36.8 Other specified disorders of urethra	0.000	0.997	0.003
D73.4 Cyst of spleen	0.000	0.997	0.003
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.003	0.997	0.000
F09 Unspecified organic or symptomatic mental disorder	0.003	0.997	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.003	0.997	0.000
S82.71 Multiple fractures of lower leg (open)	0.003	0.997	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.000	0.997	0.003
D55.8 Other anaemias due to enzyme disorders	0.000	0.997	0.003
D55.3 Anaemia due to disorders of nucleotide metabolism	0.000	0.997	0.003
D55.2 Anaemia due to disorders of glycolytic enzymes	0.000	0.997	0.003
D55.1 Anaemia due to other disorders of glutathione metabolism	0.000	0.997	0.003
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.000	0.997	0.003
D57.8 Other sickle-cell disorders	0.000	0.997	0.003
D57.3 Sickle-cell trait	0.000	0.997	0.003
D57.2 Double heterozygous sickling disorders	0.000	0.997	0.003
D57.1 Sickle-cell anaemia without crisis	0.000	0.997	0.003
D57.0 Sickle-cell anaemia with crisis	0.000	0.997	0.003
D56.9 Thalassaemia, unspecified	0.000	0.997	0.003
D56.8 Other thalassaemias	0.000	0.997	0.003
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.000	0.997	0.003
D56.2 Delta-beta thalassaemia	0.000	0.997	0.003
D56.1 Beta thalassaemia	0.000	0.997	0.003
D56.0 Alpha thalassaemia	0.000	0.997	0.003
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.000	0.997	0.003
D73.1 Hypersplenism	0.000	0.997	0.002
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.997	0.003
D56.3 Thalassaemia trait	0.000	0.997	0.003
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.003	0.997	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.997	0.003
S82.51 Fracture of medial malleolus (open)	0.003	0.997	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.997	0.003
D59.8 Other acquired haemolytic anaemias	0.000	0.997	0.002
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.997	0.002
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.997	0.002
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.997	0.002
D59.3 Haemolytic-uraemic syndrome	0.000	0.997	0.002
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.997	0.002
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.997	0.002
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.000	0.997	0.003
D81.9 Combined immunodeficiency, unspecified	0.000	0.997	0.002
D81.8 Other combined immunodeficiencies	0.000	0.997	0.002
D81.7 Major histocompatibility complex class II deficiency	0.000	0.997	0.002
D81.6 Major histocompatibility complex class I deficiency	0.000	0.997	0.002
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.997	0.002
D81.4 Nezelof's syndrome	0.000	0.997	0.002
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.997	0.002
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.997	0.002
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.997	0.002
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.997	0.002
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.997	0.002
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.997	0.002
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.997	0.002
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.997	0.002
D82.2 Immunodeficiency with short-limbed stature	0.000	0.997	0.002
D82.1 Di George's syndrome	0.000	0.997	0.002
D82.0 Wiskott-Aldrich syndrome	0.000	0.997	0.002
D83.9 Common variable immunodeficiency, unspecified	0.000	0.997	0.002
D83.8 Other common variable immunodeficiencies	0.000	0.997	0.002
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.997	0.002
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.997	0.002
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.997	0.002
K61.0 Anal abscess	0.003	0.997	0.000
Z50.0 Cardiac rehabilitation	0.003	0.997	0.000
S82.50 Fracture of medial malleolus (closed)	0.003	0.997	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.000	0.997	0.002
D58.2 Other haemoglobinopathies	0.000	0.997	0.002
D58.1 Hereditary elliptocytosis	0.000	0.997	0.002
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.997	0.003
D61 Other aplastic anaemias	0.000	0.997	0.003
D62 Acute posthaemorrhagic anaemia	0.000	0.997	0.003
S82.8 Fractures of other parts of lower leg	0.003	0.997	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.997	0.003
S82.2 Fracture of shaft of tibia	0.003	0.997	0.000
Y45.8 Other analgesics and antipyretics	0.002	0.997	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.997	0.002
D59.1 Other autoimmune haemolytic anaemias	0.000	0.997	0.002
M81.2 Osteoporosis of disuse	0.003	0.997	0.000
S82.0 Fracture of patella	0.003	0.997	0.000
D84.8 Other specified immunodeficiencies	0.000	0.997	0.002
D84.1 Defects in the complement system	0.000	0.997	0.002
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.997	0.002
M81.3 Postsurgical malabsorption osteoporosis	0.002	0.997	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.997	0.003
D66 Hereditary factor VIII deficiency	0.001	0.997	0.002
I71 Aortic aneurysm and dissection	0.003	0.997	0.000
F05.8 Other delirium	0.002	0.997	0.000
F00 Dementia in Alzheimer's disease	0.003	0.997	0.000
D86.3 Sarcoidosis of skin	0.000	0.997	0.002
E11.4 With neurological complications	0.003	0.997	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.997	0.002
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.997	0.002
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.997	0.002
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.997	0.002
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.997	0.002
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.997	0.002
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.997	0.002
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.997	0.002
N64.8 Other specified disorders of breast	0.000	0.997	0.003
Q61.2 Polycystic kidney, adult type	0.003	0.997	0.000
D52.9 Folate deficiency anaemia, unspecified	0.000	0.997	0.002
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.997	0.002
F02.3 Dementia in Parkinson's disease	0.002	0.997	0.000
M81.8 Other osteoporosis	0.002	0.997	0.000
M81.6 Localised osteoporosis [Lequesne]	0.002	0.997	0.000
M81.5 Idiopathic osteoporosis	0.002	0.997	0.000
M81.1 Postoophorectomy osteoporosis	0.002	0.997	0.000
M81.0 Postmenopausal osteoporosis	0.002	0.997	0.000
S64.4 Injury of digital nerve of other finger	0.000	0.997	0.003
W55.0 Home	0.002	0.997	0.000
D63.0 Anaemia in neoplastic disease	0.000	0.998	0.002
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.998	0.002
D89.3 Immune reconstitution syndrome	0.000	0.998	0.002
F05.9 Delirium, unspecified	0.002	0.998	0.000
F05.1 Delirium superimposed on dementia	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.000	0.998	0.002
W55.8 Other specified place	0.002	0.998	0.000
F31 Bipolar affective disorder	0.000	0.998	0.002
D73.5 Infarction of spleen	0.000	0.998	0.002
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.998	0.002
W55 Bitten or struck by other mammals	0.002	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.998	0.002
C09.9 Tonsil, unspecified	0.000	0.998	0.002
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.998	0.002
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.998	0.002
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.002	0.998	0.000
F02.2 Dementia in Huntington's disease	0.002	0.998	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.002	0.998	0.000
Z03.3 Observation for suspected nervous system disorder	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations