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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9797861
log Bayes Factor = 7.3882
Chromosome 19   position 10,743,126  (GRCh37) Explore rs9797861 on Ensembl!
Variant rs9797861 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I26.9 Pulmonary embolism without mention of acute cor pulmonale
1.000 0.000 0.000
Z86.7 Personal history of diseases of the circulatory system
0.924 0.076 0.000
I25.1 Atherosclerotic heart disease
0.918 0.082 0.000
I26 Pulmonary embolism
0.874 0.126 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.802 0.198 0.000
I80 Phlebitis and thrombophlebitis
0.796 0.204 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.771 0.229 0.000
I25 Chronic ischaemic heart disease
0.758 0.242 0.000
I20-I25 Ischaemic heart diseases
0.755 0.245 0.000
Chapter IX Diseases of the circulatory system
0.742 0.258 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.737 0.263 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.737 0.263 0.000
I24 Other acute ischaemic heart diseases
0.725 0.275 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.713 0.287 0.000
I82 Other venous embolism and thrombosis
0.673 0.327 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.657 0.343 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.656 0.344 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.620 0.380 0.000
I24.8 Other forms of acute ischaemic heart disease
0.611 0.389 0.000
I23 Certain current complications following acute myocardial infarction
0.611 0.389 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.605 0.395 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.594 0.406 0.000
I24.1 Dressler's syndrome
0.586 0.414 0.000
I82.8 Embolism and thrombosis of other specified veins
0.584 0.416 0.000
I82.9 Embolism and thrombosis of unspecified vein
0.573 0.427 0.000
I28 Other diseases of pulmonary vessels
0.566 0.434 0.000
I21 Acute myocardial infarction
0.558 0.442 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.553 0.447 0.000
I25.6 Silent myocardial ischaemia
0.546 0.454 0.000
I89.1 Lymphangitis
0.545 0.455 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.541 0.459 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.538 0.462 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.535 0.465 0.000
I00-I02 Acute rheumatic fever
0.529 0.471 0.000
I82.2 Embolism and thrombosis of vena cava
0.516 0.484 0.000
I25.2 Old myocardial infarction
0.516 0.484 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.511 0.489 0.000
I22 Subsequent myocardial infarction
0.509 0.491 0.000
I23.8 Other current complications following acute myocardial infarction
0.507 0.492 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.500 0.500 0.000
I88 Nonspecific lymphadenitis
0.488 0.512 0.000
I82.3 Embolism and thrombosis of renal vein
0.484 0.516 0.000
I82.1 Thrombophlebitis migrans
0.482 0.518 0.000
I86 Varicose veins of other sites
0.467 0.533 0.000
I25.5 Ischaemic cardiomyopathy
0.449 0.551 0.000
I82.0 Budd-Chiari syndrome
0.441 0.559 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.438 0.562 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.438 0.562 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.438 0.562 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.438 0.562 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.438 0.562 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.438 0.562 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.438 0.562 0.000
I28.0 Arteriovenous fistula of pulmonary vessels
0.435 0.564 0.000
I89.0 Lymphoedema, not elsewhere classified
0.417 0.583 0.000
I28.1 Aneurysm of pulmonary artery
0.406 0.594 0.000
I28.9 Disease of pulmonary vessels, unspecified
0.405 0.595 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.404 0.596 0.000
I60-I69 Cerebrovascular diseases
0.404 0.596 0.000
I88.8 Other nonspecific lymphadenitis
0.401 0.599 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.400 0.600 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.396 0.603 0.000
I28.8 Other specified diseases of pulmonary vessels
0.385 0.614 0.000
I86.3 Vulval varices
0.383 0.617 0.000
I87 Other disorders of veins
0.381 0.619 0.000
I02 Rheumatic chorea
0.379 0.621 0.000
I01 Rheumatic fever with heart involvement
0.379 0.621 0.000
I60 Subarachnoid haemorrhage
0.379 0.621 0.000
I86.8 Varicose veins of other specified sites
0.377 0.623 0.000
I00 Rheumatic fever without mention of heart involvement
0.375 0.624 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.370 0.630 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.352 0.648 0.000
I88.1 Chronic lymphadenitis, except mesenteric
0.350 0.650 0.000
I88.0 Nonspecific mesenteric lymphadenitis
0.348 0.652 0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.347 0.653 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.347 0.653 0.000
I22.8 Subsequent myocardial infarction of other sites
0.346 0.654 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.342 0.658 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.339 0.661 0.000
I86.0 Sublingual varices
0.335 0.665 0.000
I87.8 Other specified disorders of veins
0.329 0.671 0.000
I86.2 Pelvic varices
0.326 0.674 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.325 0.675 0.000
I63 Cerebral infarction
0.296 0.704 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.294 0.706 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.288 0.712 0.000
I60.8 Other subarachnoid haemorrhage
0.287 0.713 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.718 0.282
I87.9 Disorder of vein, unspecified
0.282 0.718 0.000
I85 Oesophageal varices
0.280 0.719 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.720 0.280
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.279 0.721 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.721 0.279
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.725 0.275
I25.4 Coronary artery aneurysm
0.273 0.726 0.001
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.726 0.273
I68 Cerebrovascular disorders in diseases classified elsewhere
0.272 0.727 0.000
I66.0 Occlusion and stenosis of middle cerebral artery
0.272 0.728 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.272 0.728 0.000
I01.8 Other acute rheumatic heart disease
0.272 0.728 0.000
I01.2 Acute rheumatic myocarditis
0.272 0.728 0.000
I01.1 Acute rheumatic endocarditis
0.272 0.728 0.000
I01.0 Acute rheumatic pericarditis
0.272 0.728 0.000
I02.9 Rheumatic chorea without heart involvement
0.272 0.728 0.000
I02.0 Rheumatic chorea with heart involvement
0.272 0.728 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.272 0.728 0.000
I05-I09 Chronic rheumatic heart diseases
0.272 0.728 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.272 0.728 0.000
I87.0 Postphlebitic syndrome
0.267 0.732 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.737 0.263
I86.4 Gastric varices
0.262 0.738 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.744 0.256
I70-I79 Diseases of arteries, arterioles and capillaries
0.256 0.744 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.000 0.744 0.256
I25.3 Aneurysm of heart
0.255 0.745 0.001
I71 Aortic aneurysm and dissection
0.255 0.745 0.000
I66.3 Occlusion and stenosis of cerebellar arteries
0.254 0.746 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.251 0.748 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.251 0.749 0.000
I66.8 Occlusion and stenosis of other cerebral artery
0.248 0.752 0.000
I66.2 Occlusion and stenosis of posterior cerebral artery
0.247 0.752 0.000
T43.2 Other and unspecified antidepressants
0.000 0.753 0.247
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.246 0.754 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.245 0.755 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.000 0.756 0.244
I66.1 Occlusion and stenosis of anterior cerebral artery
0.243 0.757 0.000
I67 Other cerebrovascular diseases
0.239 0.761 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.761 0.239
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.236 0.764 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.765 0.235
I22.1 Subsequent myocardial infarction of inferior wall
0.233 0.767 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.000 0.769 0.231
I06 Rheumatic aortic valve diseases
0.230 0.770 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.228 0.771 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.227 0.773 0.000
T50.8 Diagnostic agents
0.000 0.774 0.226
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.000 0.775 0.225
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.224 0.776 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.224 0.776 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.222 0.778 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.780 0.220
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.783 0.217
T45.0 Antiallergic and antiemetic drugs
0.000 0.784 0.216
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.212 0.788 0.000
I88.9 Nonspecific lymphadenitis, unspecified
0.209 0.790 0.001
I25.9 Chronic ischaemic heart disease, unspecified
0.209 0.791 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.000 0.791 0.209
I63.8 Other cerebral infarction
0.208 0.792 0.000
T43.9 Psychotropic drug, unspecified
0.000 0.793 0.207
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.207 0.793 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.794 0.206
T50.1 Loop [high-ceiling] diuretics
0.000 0.794 0.206
I83 Varicose veins of lower extremities
0.204 0.796 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.797 0.203
T40.2 Other opioids
0.000 0.797 0.203
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.202 0.798 0.000
I86.1 Scrotal varices
0.202 0.798 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.201 0.799 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.000 0.799 0.201
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.000 0.799 0.201
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.000 0.799 0.201
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.000 0.799 0.201
T44.1 Other parasympathomimetics [cholinergics]
0.000 0.799 0.201
T44.0 Anticholinesterase agents
0.000 0.799 0.201
I81 Portal vein thrombosis
0.200 0.799 0.001
I10-I15 Hypertensive diseases
0.201 0.799 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.200 0.800 0.000
T50.7 Analeptics and opioid receptor antagonists
0.000 0.800 0.200
T50.5 Appetite depressants
0.000 0.800 0.200
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.800 0.200
T50.0 Mineralocorticoids and their antagonists
0.000 0.800 0.200
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.000 0.800 0.199
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.199 0.801 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.802 0.198
T43.8 Other psychotropic drugs, not elsewhere classified
0.000 0.803 0.197
I20 Angina pectoris
0.197 0.803 0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.195 0.804 0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.195 0.804 0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.195 0.804 0.000
I70 Atherosclerosis
0.193 0.807 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.807 0.192
I67.8 Other specified cerebrovascular diseases
0.191 0.809 0.000
I67.1 Cerebral aneurysm, nonruptured
0.189 0.811 0.000
I62 Other nontraumatic intracranial haemorrhage
0.188 0.812 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.812 0.188
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.814 0.186
I06.0 Rheumatic aortic stenosis
0.186 0.814 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.814 0.186
I27 Other pulmonary heart diseases
0.185 0.815 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.183 0.817 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.183 0.817 0.000
I87.1 Compression of vein
0.182 0.817 0.000
T40.4 Other synthetic narcotics
0.000 0.817 0.183
I71.3 Abdominal aortic aneurysm, ruptured
0.181 0.819 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.819 0.181
T43.6 Psychostimulants with abuse potential
0.000 0.819 0.181
I67.0 Dissection of cerebral arteries, nonruptured
0.179 0.821 0.000
I63.9 Cerebral infarction, unspecified
0.179 0.821 0.000
I68.0 Cerebral amyloid angiopathy
0.178 0.822 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.178 0.822 0.000
I21.4 Acute subendocardial myocardial infarction
0.178 0.822 0.000
T50.4 Drugs affecting uric acid metabolism
0.000 0.823 0.177
I07 Rheumatic tricuspid valve diseases
0.177 0.823 0.000
T36 Poisoning by systemic antibiotics
0.000 0.823 0.177
T40.6 Other and unspecified narcotics
0.000 0.823 0.176
I71.1 Thoracic aortic aneurysm, ruptured
0.176 0.824 0.000
I85.0 Oesophageal varices with bleeding
0.175 0.825 0.000
I06.2 Rheumatic aortic stenosis with insufficiency
0.175 0.825 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.000 0.825 0.175
I06.9 Rheumatic aortic valve disease, unspecified
0.174 0.826 0.000
I65.1 Occlusion and stenosis of basilar artery
0.174 0.826 0.000
T40.1 Heroin
0.000 0.826 0.173
T37.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.827 0.173
T45.4 Iron and its compounds
0.000 0.827 0.172
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.172 0.828 0.000
I67.5 Moyamoya disease
0.172 0.828 0.000
I67.4 Hypertensive encephalopathy
0.172 0.828 0.000
I67.3 Progressive vascular leukoencephalopathy
0.172 0.828 0.000
I06.1 Rheumatic aortic insufficiency
0.171 0.828 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.000 0.829 0.171
T45.8 Other primarily systemic and haematological agents
0.000 0.829 0.171
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.000 0.829 0.171
T45.6 Fibrinolysis-affecting drugs
0.000 0.829 0.171
T45.3 Enzymes, not elsewhere classified
0.000 0.829 0.171
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.169 0.831 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.000 0.831 0.169
T40.8 Lysergide [LSD]
0.000 0.831 0.169
T40.7 Cannabis (derivatives)
0.000 0.831 0.169
T40.0 Opium
0.000 0.831 0.169
I67.2 Cerebral atherosclerosis
0.169 0.831 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.167 0.832 0.000
I09 Other rheumatic heart diseases
0.167 0.833 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.000 0.834 0.166
T45.5 Anticoagulants
0.000 0.834 0.166
I65.0 Occlusion and stenosis of vertebral artery
0.166 0.834 0.000
I06.8 Other rheumatic aortic valve diseases
0.165 0.835 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.165 0.835 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.836 0.164
T45.1 Antineoplastic and immunosuppressive drugs
0.000 0.836 0.163
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.837 0.163
T37.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.838 0.162
T45.2 Vitamins, not elsewhere classified
0.000 0.839 0.161
I15 Secondary hypertension
0.160 0.840 0.000
T40.3 Methadone
0.000 0.840 0.160
T38.0 Glucocorticoids and synthetic analogues
0.000 0.840 0.160
I83.0 Varicose veins of lower extremities with ulcer
0.159 0.841 0.000
I70.0 Atherosclerosis of aorta
0.159 0.841 0.000
T48.5 Anti-common-cold drugs
0.000 0.842 0.158
I20.9 Angina pectoris, unspecified
0.158 0.842 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.842 0.158
T37.5 Antiviral drugs
0.000 0.842 0.158
T37.4 Anthelminthics
0.000 0.842 0.158
T37.3 Other antiprotozoal drugs
0.000 0.842 0.158
T37.1 Antimycobacterial drugs
0.000 0.842 0.158
T37.0 Sulphonamides
0.000 0.842 0.158
I21.9 Acute myocardial infarction, unspecified
0.158 0.842 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.000 0.842 0.157
I70.1 Atherosclerosis of renal artery
0.157 0.843 0.000
T38.5 Other oestrogens and progestogens
0.000 0.843 0.156
I65.8 Occlusion and stenosis of other precerebral artery
0.156 0.843 0.000
T38.9 Other and unspecified hormone antagonists
0.000 0.844 0.156
T38.7 Androgens and anabolic congeners
0.000 0.844 0.156
T38.4 Oral contraceptives
0.000 0.844 0.156
T38.2 Antithyroid drugs
0.000 0.844 0.156
I21.1 Acute transmural myocardial infarction of inferior wall
0.155 0.845 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.845 0.155
I95-I99 Other and unspecified disorders of the circulatory system
0.154 0.846 0.000
I13 Hypertensive heart and renal disease
0.152 0.847 0.000
T42.3 Barbiturates
0.000 0.851 0.149
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.852 0.148
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.852 0.148
T48.4 Expectorants
0.000 0.852 0.148
T48.3 Antitussives
0.000 0.852 0.148
T48.2 Other and unspecified agents primarily acting on muscles
0.000 0.852 0.148
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.852 0.148
T48.0 Oxytocic drugs
0.000 0.852 0.148
T41.2 Other and unspecified general anaesthetics
0.000 0.853 0.147
T41.5 Therapeutic gases
0.000 0.854 0.146
T41.4 Anaesthetic, unspecified
0.000 0.854 0.146
T41.3 Local anaesthetics
0.000 0.854 0.146
T41.1 Intravenous anaesthetics
0.000 0.854 0.146
T41.0 Inhaled anaesthetics
0.000 0.854 0.146
T40.5 Cocaine
0.000 0.858 0.142
I27.8 Other specified pulmonary heart diseases
0.142 0.858 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.000 0.859 0.141
I70.8 Atherosclerosis of other arteries
0.140 0.860 0.000
T47.0 Histamine H(2)-receptor antagonists
0.000 0.861 0.139
I70.9 Generalised and unspecified atherosclerosis
0.139 0.861 0.000
T49.9 Topical agent, unspecified
0.000 0.862 0.138
T49.8 Other topical agents
0.000 0.862 0.138
T49.7 Dental drugs, topically applied
0.000 0.862 0.138
T49.6 Otorhinolaryngological drugs and preparations
0.000 0.862 0.138
T49.5 Ophthalmological drugs and preparations
0.000 0.862 0.138
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.862 0.138
T49.3 Emollients, demulcents and protectants
0.000 0.862 0.138
T49.2 Local astringents and local detergents
0.000 0.862 0.138
T49.1 Antipruritics
0.000 0.862 0.138
T42.1 Iminostilbenes
0.000 0.862 0.138
I62.1 Nontraumatic extradural haemorrhage
0.137 0.862 0.000
T47.6 Antidiarrhoeal drugs
0.000 0.864 0.136
I65.2 Occlusion and stenosis of carotid artery
0.136 0.864 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.000 0.865 0.135
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.865 0.135
T42.2 Succinimides and oxazolidinediones
0.000 0.865 0.135
I70.00 Atherosclerosis of aorta (without gangrene)
0.134 0.866 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.133 0.867 0.000
T39.4 Antirheumatics, not elsewhere classified
0.000 0.867 0.133
T39.2 Pyrazolone derivatives
0.000 0.867 0.133
I27.1 Kyphoscoliotic heart disease
0.132 0.867 0.000
I78 Diseases of capillaries
0.132 0.868 0.000
I70.10 Atherosclerosis of renal artery (without gangrene)
0.131 0.869 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.000 0.870 0.130
T47.8 Other agents primarily affecting the gastro-intestinal system
0.000 0.870 0.130
T47.7 Emetics
0.000 0.870 0.130
T47.5 Digestants
0.000 0.870 0.130
T47.3 Saline and osmotic laxatives
0.000 0.870 0.130
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.000 0.872 0.128
I79.1 Aortitis in diseases classified elsewhere
0.128 0.872 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.128 0.872 0.000
I15.9 Seconday hypertension, unspecified
0.128 0.872 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.000 0.872 0.127
I07.9 Tricuspid valve disease, unspecified
0.127 0.873 0.000
I07.8 Other tricuspid valve diseases
0.127 0.873 0.000
I07.2 Tricuspid stenosis with insufficiency
0.127 0.873 0.000
I07.0 Tricuspid stenosis
0.127 0.873 0.000
T36.9 Systemic antibiotic, unspecified
0.000 0.873 0.127
T36.7 Antifungal antibiotics, systemically used
0.000 0.873 0.127
T36.6 Rifamycins
0.000 0.873 0.127
T36.5 Aminoglycosides
0.000 0.873 0.127
T36.2 Chloramphenicol group
0.000 0.873 0.127
T38.1 Thyroid hormones and substitutes
0.000 0.873 0.127
T47.4 Other laxatives
0.000 0.874 0.126
T36.4 Tetracyclines
0.000 0.875 0.125
I83.1 Varicose veins of lower extremities with inflammation
0.124 0.876 0.000
T36.3 Macrolides
0.000 0.877 0.123
T36.0 Penicillins
0.000 0.878 0.122
I13.1 Hypertensive heart and renal disease with renal failure
0.121 0.878 0.000
I15.8 Other secondary hypertension
0.121 0.879 0.000
I15.2 Hypertension secondary to endocrine disorders
0.121 0.879 0.000
T47.2 Stimulant laxatives
0.000 0.879 0.120
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.879 0.120
I09.8 Other specified rheumatic heart diseases
0.120 0.880 0.000
I09.2 Chronic rheumatic pericarditis
0.120 0.880 0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.120 0.880 0.000
I09.0 Rheumatic myocarditis
0.120 0.880 0.000
T42.4 Benzodiazepines
0.000 0.880 0.120
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.880 0.119
I15.0 Renovascular hypertension
0.119 0.881 0.000
T46.1 Calcium-channel blockers
0.000 0.882 0.118
I99 Other and unspecified disorders of circulatory system
0.118 0.882 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.116 0.884 0.000
T36.8 Other systemic antibiotics
0.000 0.885 0.114
T39.0 Salicylates
0.000 0.885 0.115
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.000 0.886 0.114
I70.01 Atherosclerosis of aorta (with gangrene)
0.114 0.886 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.886 0.114
I20.1 Angina pectoris with documented spasm
0.114 0.886 0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.114 0.886 0.000
I70.11 Atherosclerosis of renal artery (with gangrene)
0.113 0.887 0.000
I05 Rheumatic mitral valve diseases
0.112 0.888 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.889 0.111
T46.8 Antivaricose drugs, including sclerosing agents
0.000 0.889 0.111
T46.7 Peripheral vasodilators
0.000 0.889 0.111
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.109 0.890 0.000
I07.1 Tricuspid insufficiency
0.109 0.890 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.000 0.891 0.109
I78.0 Hereditary haemorrhagic telangiectasia
0.109 0.891 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.892 0.108
I74 Arterial embolism and thrombosis
0.107 0.893 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.000 0.894 0.106
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.105 0.894 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.895 0.105
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.105 0.895 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.000 0.896 0.104
T42.0 Hydantoin derivatives
0.000 0.898 0.102
I11 Hypertensive heart disease
0.101 0.898 0.000
I70.80 Atherosclerosis of other arteries (without gangrene)
0.101 0.898 0.000
I15.1 Hypertension secondary to other renal disorders
0.101 0.899 0.000
I70.81 Atherosclerosis of other arteries (with gangrene)
0.100 0.899 0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.100 0.900 0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.100 0.900 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.099 0.900 0.000
I12 Hypertensive renal disease
0.099 0.901 0.000
I71.0 Dissection of aorta [any part]
0.098 0.902 0.000
I27.9 Pulmonary heart disease, unspecified
0.098 0.902 0.000
I61 Intracerebral haemorrhage
0.095 0.905 0.000
I09.9 Rheumatic heart disease, unspecified
0.092 0.907 0.000
I08 Multiple valve diseases
0.092 0.908 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.087 0.913 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.086 0.914 0.000
I78.9 Disease of capillaries, unspecified
0.084 0.915 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.083 0.917 0.000
I05.9 Mitral valve disease, unspecified
0.083 0.917 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.082 0.918 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.080 0.918 0.001
I98 Other disorders of circulatory system in diseases classified elsewhere
0.081 0.919 0.000
I74.8 Embolism and thrombosis of other arteries
0.080 0.920 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.076 0.924 0.000
I12.9 Hypertensive renal disease without renal failure
0.075 0.925 0.000
I05.8 Other mitral valve diseases
0.075 0.925 0.000
I05.2 Mitral stenosis with insufficiency
0.074 0.926 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.072 0.928 0.000
I78.8 Other diseases of capillaries
0.072 0.928 0.000
I74.5 Embolism and thrombosis of iliac artery
0.072 0.928 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.000 0.930 0.070
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.070 0.930 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.069 0.931 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.069 0.931 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.068 0.932 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.066 0.934 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.065 0.935 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.065 0.935 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.064 0.936 0.000
I08.8 Other multiple valve diseases
0.064 0.936 0.000
I08.9 Multiple valve disease, unspecified
0.063 0.937 0.000
I78.1 Naevus, nonneoplastic
0.063 0.937 0.000
I05.1 Rheumatic mitral insufficiency
0.061 0.938 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.061 0.939 0.001
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.060 0.940 0.000
I27.0 Primary pulmonary hypertension
0.060 0.940 0.000
I61.8 Other intracerebral haemorrhage
0.059 0.941 0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.058 0.942 0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.058 0.942 0.000
I98.0 Cardiovascular syphilis
0.058 0.942 0.000
I05.0 Mitral stenosis
0.057 0.943 0.000
I27.2 Other secondary pulmonary hypertension
0.056 0.943 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.056 0.944 0.000
I20.0 Unstable angina
0.055 0.945 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.054 0.945 0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.053 0.947 0.000
T39.1 4-Aminophenol derivatives
0.000 0.948 0.052
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.052 0.948 0.000
I72 Other aneurysm
0.050 0.950 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.047 0.953 0.000
I69 Sequelae of cerebrovascular disease
0.047 0.953 0.000
I20.8 Other forms of angina pectoris
0.046 0.954 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.044 0.956 0.000
I97.9 Postprocedural disorder of circulatory system, unspecified
0.043 0.957 0.001
I73 Other peripheral vascular diseases
0.039 0.961 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.038 0.961 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.038 0.962 0.000
I97.0 Postcardiotomy syndrome
0.037 0.962 0.001
I77 Other disorders of arteries and arterioles
0.037 0.963 0.000
M48.02 Spinal stenosis (Cervical region)
0.000 0.964 0.036
I72.6 Aneurysm and dissection of vertebral artery
0.036 0.964 0.000
I85.9 Oesophageal varices without bleeding
0.035 0.964 0.001
I98.2 Oesophageal varices in diseases classified elsewhere
0.035 0.965 0.000
I97.1 Other functional disturbances following cardiac surgery
0.034 0.965 0.001
I72.2 Aneurysm of renal artery
0.032 0.967 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.032 0.968 0.001
I72.8 Aneurysm of other specified arteries
0.032 0.968 0.000
I72.1 Aneurysm of artery of upper extremity
0.031 0.968 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.031 0.968 0.000
I08.0 Disorders of both mitral and aortic valves
0.031 0.969 0.000
I72.0 Aneurysm of carotid artery
0.030 0.969 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.030 0.970 0.000
I72.4 Aneurysm of artery of lower extremity
0.030 0.970 0.000
I77.2 Rupture of artery
0.029 0.971 0.000
I72.3 Aneurysm of iliac artery
0.028 0.972 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.027 0.973 0.000
I77.5 Necrosis of artery
0.026 0.973 0.000
I77.4 Coeliac artery compression syndrome
0.026 0.973 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.026 0.974 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.025 0.974 0.001
I08.1 Disorders of both mitral and tricuspid valves
0.025 0.975 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.025 0.975 0.000
I77.3 Arterial fibromuscular dysplasia
0.024 0.976 0.000
I73.8 Other specified peripheral vascular diseases
0.024 0.976 0.000
I69.3 Sequelae of cerebral infarction
0.024 0.976 0.000
I67.9 Cerebrovascular disease, unspecified
0.023 0.977 0.000
I77.8 Other specified disorders of arteries and arterioles
0.023 0.977 0.000
I72.9 Aneurysm of unspecified site
0.022 0.977 0.001
I77.0 Arteriovenous fistula, acquired
0.023 0.977 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.021 0.979 0.000
I77.6 Arteritis, unspecified
0.021 0.979 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.019 0.980 0.000
I95 Hypotension
0.016 0.984 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.016 0.984 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.015 0.985 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.987 0.013
Z95 Presence of cardiac and vascular implants and grafts
0.013 0.987 0.000
Z95.1 Presence of aortocoronary bypass graft
0.013 0.987 0.000
I77.1 Stricture of artery
0.012 0.988 0.000
Z95.3 Presence of xenogenic heart valve
0.012 0.988 0.000
I12.0 Hypertensive renal disease with renal failure
0.012 0.988 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.000 0.989 0.011
I95.2 Hypotension due to drugs
0.011 0.989 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.010 0.989 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.000 0.989 0.011
I95.8 Other hypotension
0.010 0.989 0.000
Z95.0 Presence of cardiac pacemaker
0.010 0.990 0.000
Z91.5 Personal history of self-harm
0.000 0.991 0.009
I95.0 Idiopathic hypotension
0.009 0.991 0.000
X63.0 Home
0.000 0.991 0.009
H52.2 Astigmatism
0.009 0.991 0.000
Z95.2 Presence of prosthetic heart valve
0.009 0.991 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.000 0.991 0.009
J45.9 Asthma, unspecified
0.000 0.992 0.008
X60-X84 Intentional self-harm
0.000 0.992 0.008
M48.0 Spinal stenosis
0.000 0.992 0.008

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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