TreeWAS – Variant ID: rs9896933

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M20.5 Other deformities of toe(s) (acquired)	0.000	0.977	0.023
J35.0 Chronic tonsillitis	0.000	0.983	0.017
M10.96 Gout, unspecified (Lower leg)	0.000	0.992	0.008
S42.20 Fracture of upper end of humerus (closed)	0.007	0.993	0.000
J06.9 Acute upper respiratory infection, unspecified	0.007	0.993	0.000
S42.2 Fracture of upper end of humerus	0.005	0.995	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.995	0.005
S22.20 Fracture of sternum (closed)	0.000	0.995	0.005
F33.9 Recurrent depressive disorder, unspecified	0.000	0.995	0.005
H83.0 Labyrinthitis	0.005	0.995	0.000
F33 Recurrent depressive disorder	0.000	0.995	0.005
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.995	0.005
Z98.1 Arthrodesis status	0.000	0.995	0.005
L60.0 Ingrowing nail	0.000	0.995	0.005
Q38.7 Pharyngeal pouch	0.004	0.996	0.000
S42.10 Fracture of scapula (closed)	0.004	0.996	0.000
S42.21 Fracture of upper end of humerus (open)	0.004	0.996	0.000
F33.8 Other recurrent depressive disorders	0.000	0.996	0.004
S42.1 Fracture of scapula	0.004	0.996	0.000
F32.0 Mild depressive episode	0.000	0.996	0.004
S42 Fracture of shoulder and upper arm	0.004	0.996	0.000
L82 Seborrhoeic keratosis	0.000	0.996	0.004
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.996	0.004
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.996	0.004
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.996	0.004
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.996	0.004
S42.3 Fracture of shaft of humerus	0.004	0.996	0.000
J35 Chronic diseases of tonsils and adenoids	0.000	0.996	0.004
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.996	0.003
D62 Acute posthaemorrhagic anaemia	0.000	0.996	0.004
H83 Other diseases of inner ear	0.003	0.996	0.000
K86.3 Pseudocyst of pancreas	0.000	0.996	0.004
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.997	0.003
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.997	0.003
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.997	0.003
B37.8 Candidiasis of other sites	0.000	0.997	0.003
C82.0 Small cleaved cell, follicular	0.000	0.997	0.003
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.997	0.003
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.003	0.997	0.000
S42.31 Fracture of shaft of humerus (open)	0.003	0.997	0.000
S42.11 Fracture of scapula (open)	0.003	0.997	0.000
H83.3 Noise effects on inner ear	0.003	0.997	0.000
J35.1 Hypertrophy of tonsils	0.000	0.997	0.003
F32 Depressive episode	0.000	0.997	0.003
M66.06 Rupture of popliteal cyst-Lower leg	0.000	0.997	0.003
S42.9 Fracture of shoulder girdle, part unspecified	0.003	0.997	0.000
H83.9 Disease of inner ear, unspecified	0.003	0.997	0.000
S42.30 Fracture of shaft of humerus (closed)	0.003	0.997	0.000
H83.8 Other specified diseases of inner ear	0.003	0.997	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.003	0.997	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.003	0.997	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.997	0.003
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.000	0.997	0.003
C82.3 Follicular lymphoma grade IIIa	0.000	0.997	0.003
F32.1 Moderate depressive episode	0.000	0.997	0.003
H83.1 Labyrinthine fistula	0.003	0.997	0.000
S40 Superficial injury of shoulder and upper arm	0.003	0.997	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.997	0.003
K86.1 Other chronic pancreatitis	0.000	0.997	0.003
C82.6 Cutaneous follicle centre lymphoma	0.000	0.997	0.003
C82.5 Diffuse follicle centre lymphoma	0.000	0.997	0.003
S64.0 Injury of ulnar nerve at wrist and hand level	0.000	0.997	0.003
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.997	0.003
J06 Acute upper respiratory infections of multiple and unspecified sites	0.003	0.997	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.997	0.003
C82.2 Large cell, follicular	0.000	0.997	0.003
F30.9 Manic episode, unspecified	0.000	0.997	0.003
S22.2 Fracture of sternum	0.000	0.997	0.003
S40.0 Contusion of shoulder and upper arm	0.003	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.997	0.003
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.997	0.002
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.000	0.997	0.003
C82.4 Follicular lymphoma grade IIIb	0.000	0.997	0.002
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.003	0.997	0.000
T50.4 Drugs affecting uric acid metabolism	0.000	0.997	0.003
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.997	0.003
H83.2 Labyrinthine dysfunction	0.002	0.997	0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.000	0.997	0.002
S40.8 Other superficial injuries of shoulder and upper arm	0.002	0.997	0.000
S40-S49 Injuries to the shoulder and upper arm	0.003	0.997	0.000
C09.9 Tonsil, unspecified	0.000	0.997	0.003
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.003	0.997	0.000
H44.2 Degenerative myopia	0.000	0.997	0.003
Z73.3 Stress, not elsewhere classified	0.000	0.997	0.003
M19.97 Arthrosis, unspecified (Ankle and foot)	0.000	0.997	0.003
H02.9 Disorder of eyelid, unspecified	0.000	0.997	0.002
M31.3 Wegener's granulomatosis	0.000	0.997	0.002
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.002	0.998	0.000
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.002	0.998	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.998	0.002
F32.8 Other depressive episodes	0.000	0.998	0.002
K35.0 Acute appendicitis with generalised peritonitis	0.002	0.998	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.002	0.998	0.000
M66.0 Rupture of popliteal cyst	0.000	0.998	0.002
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.002	0.998	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.002	0.998	0.000
C01 Malignant neoplasm of base of tongue	0.000	0.998	0.002
T50.8 Diagnostic agents	0.000	0.998	0.002
F30 Manic episode	0.000	0.998	0.002
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.002	0.998	0.000
T50.1 Loop [high-ceiling] diuretics	0.000	0.998	0.002
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
S42.0 Fracture of clavicle	0.002	0.998	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
F30-F39 Mood [affective] disorders	0.000	0.998	0.002
M31.6 Other giant cell arteritis	0.000	0.998	0.002
T43.9 Psychotropic drug, unspecified	0.000	0.998	0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.998	0.002
S40.7 Multiple superficial injuries of shoulder and upper arm	0.002	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.998	0.002
J06.8 Other acute upper respiratory infections of multiple sites	0.002	0.998	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
T50.7 Analeptics and opioid receptor antagonists	0.000	0.998	0.002
T50.5 Appetite depressants	0.000	0.998	0.002
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.998	0.002
T50.0 Mineralocorticoids and their antagonists	0.000	0.998	0.002
S22.21 Fracture of sternum (open)	0.000	0.998	0.002
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.998	0.002
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.002	0.998	0.000
H36.0 Diabetic retinopathy	0.002	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.998	0.002
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.998	0.002
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.998	0.002
T44.0 Anticholinesterase agents	0.000	0.998	0.002
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.998	0.002
W22.9 Unspecified place	0.002	0.998	0.000
M31 Other necrotising vasculopathies	0.000	0.998	0.002
D47.1 Chronic myeloproliferative disease	0.002	0.998	0.000
J35.2 Hypertrophy of adenoids	0.000	0.998	0.002
S42.4 Fracture of lower end of humerus	0.002	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.998	0.002
K86 Other diseases of pancreas	0.000	0.998	0.002
S44 Injury of nerves at shoulder and upper arm level	0.002	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.002
F30.1 Mania without psychotic symptoms	0.000	0.998	0.002
D51 Vitamin B12 deficiency anaemia	0.002	0.998	0.000
S48 Traumatic amputation of shoulder and upper arm	0.002	0.998	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.002	0.998	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.002	0.998	0.000
S47 Crushing injury of shoulder and upper arm	0.002	0.998	0.000
H80.9 Otosclerosis, unspecified	0.002	0.998	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.998	0.002
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.002	0.998	0.000
C09 Malignant neoplasm of tonsil	0.000	0.998	0.002
M31.7 Microscopic polyangiitis	0.000	0.998	0.002
M31.0 Hypersensitivity angiitis	0.000	0.998	0.002
Z46.3 Fitting and adjustment of dental prosthetic device	0.000	0.998	0.002
J06.0 Acute laryngopharyngitis	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.002
S41 Open wound of shoulder and upper arm	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.998	0.002
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.998	0.002
M66.09 Rupture of popliteal cyst-Site unspec	0.000	0.998	0.002
M66.08 Rupture of popliteal cyst-Other	0.000	0.998	0.002
M66.07 Rupture of popliteal cyst-Ankle/foot	0.000	0.998	0.002
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.000	0.998	0.002
M66.04 Rupture of popliteal cyst-Hand	0.000	0.998	0.002
M66.03 Rupture of popliteal cyst-Forearm	0.000	0.998	0.002
M66.02 Rupture of popliteal cyst-Upper arm	0.000	0.998	0.002
M66.01 Rupture of popliteal cyst-Shldr region	0.000	0.998	0.002
M66.00 Rupture of popliteal cyst-Mult sites	0.000	0.998	0.002
K56.6 Other and unspecified intestinal obstruction	0.002	0.998	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.998	0.002
T45.2 Vitamins, not elsewhere classified	0.000	0.998	0.002
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
F30.8 Other manic episodes	0.000	0.998	0.002
S43.5 Sprain and strain of acromioclavicular joint	0.002	0.998	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
S42.01 Fracture of clavicle (open)	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.998	0.002
S43.1 Dislocation of acromioclavicular joint	0.002	0.998	0.000
S64.3 Injury of digital nerve of thumb	0.000	0.998	0.002
H52.2 Astigmatism	0.002	0.998	0.000
M66.4 Spontaneous rupture of other tendons	0.000	0.998	0.002
F38 Other mood [affective] disorders	0.000	0.998	0.002
S46 Injury of muscle and tendon at shoulder and upper arm level	0.002	0.998	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.000	0.998	0.002
T46.1 Calcium-channel blockers	0.000	0.998	0.002
M31.4 Aortic arch syndrome [Takayasu]	0.000	0.998	0.002
S44.2 Injury of radial nerve at upper arm level	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.000	0.998	0.002
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
B07 Viral warts	0.002	0.998	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.002	0.998	0.000
S64 Injury of nerves at wrist and hand level	0.000	0.998	0.002
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.998	0.002
C09.0 Tonsillar fossa	0.000	0.998	0.002
M31.2 Lethal midline granuloma	0.000	0.998	0.002
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
S46.3 Injury of muscle and tendon of triceps	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.002
T46.7 Peripheral vasodilators	0.000	0.998	0.002
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.002
M66 Spontaneous rupture of synovium and tendon	0.000	0.998	0.002
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.998	0.002
D51.8 Other vitamin B12 deficiency anaemias	0.002	0.998	0.000
F30.2 Mania with psychotic symptoms	0.000	0.998	0.002
L89.1 Stage II decubitus ulcer	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.002
H80 Otosclerosis	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.000	0.998	0.002
M25.37 Other instability of joint (Ankle and foot)	0.000	0.998	0.002
H49.1 Fourth [trochlear] nerve palsy	0.002	0.998	0.000
M31.9 Necrotising vasculopathy, unspecified	0.000	0.998	0.002
M31.8 Other specified necrotising vasculopathies	0.000	0.998	0.002
M31.1 Thrombotic microangiopathy	0.000	0.998	0.002
S44.9 Injury of unspecified nerve at shoulder and upper arm level	0.002	0.998	0.000
S44.8 Injury of other nerves at shoulder and upper arm level	0.002	0.998	0.000
S44.7 Injury of multiple nerves at shoulder and upper arm level	0.002	0.998	0.000
S44.5 Injury of cutaneous sensory nerve at shoulder and upper arm level	0.002	0.998	0.000
S44.4 Injury of musculocutaneous nerve	0.002	0.998	0.000
S44.3 Injury of axillary nerve	0.002	0.998	0.000
S44.1 Injury of median nerve at upper arm level	0.002	0.998	0.000
S44.0 Injury of ulnar nerve at upper arm level	0.002	0.998	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.002	0.998	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
C09.1 Tonsillar pillar (anterior) (posterior)	0.000	0.998	0.002
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.002
T47.0 Histamine H(2)-receptor antagonists	0.000	0.998	0.002
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.000	0.998	0.002
D51.2 Transcobalamin II deficiency	0.002	0.998	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.002	0.998	0.000
S48.9 Traumatic amputation of shoulder and upper arm, level unspecified	0.002	0.998	0.000
S48.1 Traumatic amputation at level between shoulder and elbow	0.002	0.998	0.000
S48.0 Traumatic amputation at shoulder joint	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.998	0.002
M66.47 Spontaneous rupture of other tendons (Ankle and foot)	0.000	0.998	0.002
D51.3 Other dietary vitamin B12 deficiency anaemia	0.002	0.998	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.002	0.998	0.000
S45.9 Injury of unspecified blood vessel at shoulder and upper arm level	0.002	0.998	0.000
S45.8 Injury of other blood vessels at shoulder and upper arm level	0.002	0.998	0.000
S45.7 Injury of multiple blood vessels at shoulder and upper arm level	0.002	0.998	0.000
S45.3 Injury of superficial vein at shoulder and upper arm level	0.002	0.998	0.000
S45.2 Injury of axillary or brachial vein	0.002	0.998	0.000
S45.1 Injury of brachial artery	0.002	0.998	0.000
S45.0 Injury of axillary artery	0.002	0.998	0.000
T45.5 Anticoagulants	0.000	0.998	0.002
C09.8 Overlapping lesion of tonsil	0.000	0.998	0.002
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.998	0.002
M66.2 Spontaneous rupture of extensor tendons	0.000	0.998	0.002
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.002
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.998	0.002
T38.1 Thyroid hormones and substitutes	0.000	0.998	0.002
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.998	0.002
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.000	0.998	0.002
S42.41 Fracture of lower end of humerus (open)	0.001	0.998	0.000
S43.2 Dislocation of sternoclavicular joint	0.002	0.998	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.998	0.002
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.998	0.002
T47.7 Emetics	0.000	0.998	0.002
T47.5 Digestants	0.000	0.998	0.002
T47.3 Saline and osmotic laxatives	0.000	0.998	0.002
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.998	0.002
S41.7 Multiple open wounds of shoulder and upper arm	0.002	0.998	0.000
S49.8 Other specified injuries of shoulder and upper arm	0.002	0.998	0.000
S64.1 Injury of median nerve at wrist and hand level	0.000	0.998	0.002
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.998	0.002
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.998	0.002
T45.8 Other primarily systemic and haematological agents	0.000	0.998	0.002
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.998	0.002
T45.6 Fibrinolysis-affecting drugs	0.000	0.998	0.002
T45.3 Enzymes, not elsewhere classified	0.000	0.998	0.002
T47.4 Other laxatives	0.000	0.998	0.002
T47.2 Stimulant laxatives	0.000	0.998	0.002
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.002
H49.0 Third [oculomotor] nerve palsy	0.002	0.998	0.000
M67.8 Other specified disorders of synovium and tendon	0.000	0.998	0.002
T38.9 Other and unspecified hormone antagonists	0.000	0.998	0.002
T38.7 Androgens and anabolic congeners	0.000	0.998	0.002
T38.5 Other oestrogens and progestogens	0.000	0.998	0.002
T38.4 Oral contraceptives	0.000	0.998	0.002
T38.2 Antithyroid drugs	0.000	0.998	0.002
T38.0 Glucocorticoids and synthetic analogues	0.000	0.998	0.002
T47.6 Antidiarrhoeal drugs	0.000	0.998	0.002
H49 Paralytic strabismus	0.002	0.998	0.000
F38.0 Other single mood [affective] disorders	0.000	0.998	0.001
K35.3 Acute appendicitis with localized peritonitis	0.002	0.998	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.002	0.998	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.000	0.998	0.002
T36.3 Macrolides	0.000	0.998	0.002
T45.4 Iron and its compounds	0.000	0.998	0.002
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.000	0.998	0.002
K35.8 Acute appendicitis, other and unspecified	0.002	0.998	0.000
T36.4 Tetracyclines	0.000	0.998	0.001
M66.49 Spontaneous rupture of other tendons (Site unspecified)	0.000	0.998	0.001
M66.48 Spontaneous rupture of other tendons (Other)	0.000	0.998	0.001
M66.45 Spontaneous rupture of other tendons (Pelvic region and thigh)	0.000	0.998	0.001
M66.44 Spontaneous rupture of other tendons (Hand)	0.000	0.998	0.001
M66.43 Spontaneous rupture of other tendons (Forearm)	0.000	0.998	0.001
M66.42 Spontaneous rupture of other tendons (Upper arm)	0.000	0.998	0.001
M66.40 Spontaneous rupture of other tendons (Multiple sites)	0.000	0.998	0.001
F38.1 Other recurrent mood [affective] disorders	0.000	0.998	0.001
H49.8 Other paralytic strabismus	0.002	0.998	0.000
M67.0 Short Achilles tendon (acquired)	0.000	0.998	0.002
S43.4 Sprain and strain of shoulder joint	0.001	0.998	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.001	0.998	0.000
H72.0 Central perforation of tympanic membrane	0.002	0.998	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.002	0.998	0.000
S41.1 Open wound of upper arm	0.001	0.998	0.000
Z96.0 Presence of urogenital implants	0.000	0.998	0.002
F34 Persistent mood [affective] disorders	0.000	0.998	0.001
H80-H83 Diseases of inner ear	0.002	0.998	0.000
H49.2 Sixth [abducent] nerve palsy	0.002	0.998	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.001	0.998	0.000
Q38.3 Other congenital malformations of tongue	0.001	0.998	0.000
Q38.2 Macroglossia	0.001	0.998	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.001	0.998	0.000
S49.7 Multiple injuries of shoulder and upper arm	0.001	0.998	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.000	0.998	0.001
S64.8 Injury of other nerves at wrist and hand level	0.000	0.998	0.001
T49.9 Topical agent, unspecified	0.000	0.998	0.001
T49.8 Other topical agents	0.000	0.998	0.001
T49.7 Dental drugs, topically applied	0.000	0.998	0.001
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.998	0.001
T49.5 Ophthalmological drugs and preparations	0.000	0.998	0.001
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.998	0.001
T49.3 Emollients, demulcents and protectants	0.000	0.998	0.001
T49.2 Local astringents and local detergents	0.000	0.998	0.001
T49.1 Antipruritics	0.000	0.998	0.001
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.000	0.998	0.001
H80.2 Cochlear otosclerosis	0.001	0.998	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.001	0.998	0.000
M66.1 Rupture of synovium	0.000	0.998	0.001
Q38.0 Congenital malformations of lips, not elsewhere classified	0.001	0.998	0.000
S41.0 Open wound of shoulder	0.001	0.998	0.000
T41.5 Therapeutic gases	0.000	0.998	0.001
T41.4 Anaesthetic, unspecified	0.000	0.998	0.001
T41.3 Local anaesthetics	0.000	0.998	0.001
T41.1 Intravenous anaesthetics	0.000	0.998	0.001
T41.0 Inhaled anaesthetics	0.000	0.998	0.001
Z73.8 Other problems related to life-management difficulty	0.000	0.998	0.002
M24.24 Disorder of ligament (Hand)	0.000	0.998	0.002
F30.0 Hypomania	0.000	0.998	0.001
F38.8 Other specified mood [affective] disorders	0.000	0.998	0.001
H80.8 Other otosclerosis	0.001	0.998	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.001	0.998	0.000
K86.9 Disease of pancreas, unspecified	0.000	0.998	0.002
M67.2 Synovial hypertrophy, not elsewhere classified	0.000	0.998	0.002
T36.9 Systemic antibiotic, unspecified	0.000	0.998	0.001
T36.7 Antifungal antibiotics, systemically used	0.000	0.998	0.001
T36.6 Rifamycins	0.000	0.998	0.001
T36.5 Aminoglycosides	0.000	0.998	0.001
T36.2 Chloramphenicol group	0.000	0.998	0.001
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.998	0.002
F80.1 Expressive language disorder	0.002	0.998	0.000
H49.9 Paralytic strabismus, unspecified	0.001	0.998	0.000
F39 Unspecified mood [affective] disorder	0.000	0.998	0.001
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.998	0.002
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.002	0.998	0.000
M10.9 Gout, unspecified	0.000	0.998	0.002
T36.8 Other systemic antibiotics	0.000	0.998	0.001
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.998	0.001
K35 Acute appendicitis	0.002	0.998	0.000
M67 Other disorders of synovium and tendon	0.000	0.998	0.002
O21.0 Mild hyperemesis gravidarum	0.000	0.998	0.002
Q38.8 Other congenital malformations of pharynx	0.001	0.998	0.000
Q38.6 Other congenital malformations of mouth	0.001	0.998	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.001	0.998	0.000
Q38.1 Ankyloglossia	0.001	0.998	0.000
T41.2 Other and unspecified general anaesthetics	0.000	0.998	0.001
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.000	0.998	0.001
M66.28 Spontaneous rupture of extensor tendons-Other	0.000	0.998	0.001
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.000	0.998	0.001
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.000	0.998	0.001
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.000	0.998	0.001
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.000	0.998	0.001
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.000	0.998	0.001
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.001	0.998	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.002	0.998	0.000
H35.8 Other specified retinal disorders	0.002	0.998	0.000
H35.0 Background retinopathy and retinal vascular changes	0.002	0.998	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.998	0.001
T42.3 Barbiturates	0.000	0.998	0.001
Z51.8 Other specified medical care	0.000	0.998	0.002
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.998	0.001
T37.5 Antiviral drugs	0.000	0.998	0.001
T37.4 Anthelminthics	0.000	0.998	0.001
T37.3 Other antiprotozoal drugs	0.000	0.998	0.001
T37.1 Antimycobacterial drugs	0.000	0.998	0.001
T37.0 Sulphonamides	0.000	0.998	0.001
Z73 Problems related to life-management difficulty	0.000	0.998	0.002
H49.3 Total (external) ophthalmoplegia	0.001	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.998	0.001
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.998	0.001
T48.4 Expectorants	0.000	0.998	0.001
T48.3 Antitussives	0.000	0.998	0.001
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.998	0.001
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.998	0.001
T48.0 Oxytocic drugs	0.000	0.998	0.001
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.002	0.998	0.000
H36 Retinal disorders in diseases classified elsewhere	0.001	0.998	0.000
M10.92 Gout, unspecified (Upper arm)	0.000	0.999	0.001
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.001	0.999	0.000
M10.93 Gout, unspecified (Forearm)	0.000	0.999	0.001
M66.5 Spontaneous rupture of unspecified tendon	0.000	0.999	0.001
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.000	0.999	0.001
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.999	0.001
F34.8 Other persistent mood [affective] disorders	0.000	0.999	0.001
K83.9 Disease of biliary tract, unspecified	0.000	0.999	0.001
K86.2 Cyst of pancreas	0.000	0.999	0.001
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.999	0.001
H82 Vertiginous syndromes in diseases classified elsewhere	0.001	0.999	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.000	0.999	0.001
M66.3 Spontaneous rupture of flexor tendons	0.000	0.999	0.001
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.999	0.001
T42.0 Hydantoin derivatives	0.000	0.999	0.001
T48.5 Anti-common-cold drugs	0.000	0.999	0.001
Z52.4 Kidney donor	0.001	0.999	0.000
M24.26 Disorder of ligament (Lower leg)	0.000	0.999	0.001
M66.19 Rupture of synovium (Site unspecified)	0.000	0.999	0.001
M66.18 Rupture of synovium (Other)	0.000	0.999	0.001
M66.17 Rupture of synovium (Ankle and foot)	0.000	0.999	0.001
M66.16 Rupture of synovium (Lower leg)	0.000	0.999	0.001
M66.15 Rupture of synovium (Pelvic region and thigh)	0.000	0.999	0.001
M66.14 Rupture of synovium (Hand)	0.000	0.999	0.001
M66.13 Rupture of synovium (Forearm)	0.000	0.999	0.001
M66.12 Rupture of synovium (Upper arm)	0.000	0.999	0.001
M66.11 Rupture of synovium (Shoulder region)	0.000	0.999	0.001
M66.10 Rupture of synovium (Multiple sites)	0.000	0.999	0.001
G00.9 Bacterial meningitis, unspecified	0.001	0.999	0.000
T36.0 Penicillins	0.000	0.999	0.001
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.999	0.001
M10.98 Gout, unspecified (Other)	0.000	0.999	0.001
M10.95 Gout, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
M10.91 Gout, unspecified (Shoulder region)	0.000	0.999	0.001
C05.0 Hard palate	0.000	0.999	0.001
M67.9 Disorder of synovium and tendon, unspecified	0.000	0.999	0.001
M67.3 Transient synovitis	0.000	0.999	0.001
R22.9 Localised swelling, mass and lump, unspecified	0.000	0.999	0.001
T39.4 Antirheumatics, not elsewhere classified	0.000	0.999	0.001
T39.2 Pyrazolone derivatives	0.000	0.999	0.001
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.999	0.001
T42.2 Succinimides and oxazolidinediones	0.000	0.999	0.001
C04 Malignant neoplasm of floor of mouth	0.000	0.999	0.001
C00 Malignant neoplasm of lip	0.000	0.999	0.001
C00.0 External upper lip	0.000	0.999	0.001
C04.9 Floor of mouth, unspecified	0.000	0.999	0.001
F34.0 Cyclothymia	0.000	0.999	0.001
H33.2 Serous retinal detachment	0.001	0.999	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.999	0.001
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.999	0.001
G95.9 Disease of spinal cord, unspecified	0.000	0.999	0.001
H35.6 Retinal haemorrhage	0.001	0.999	0.000
H49.4 Progressive external ophthalmoplegia	0.001	0.999	0.000
M67.4 Ganglion	0.000	0.999	0.001
T42.4 Benzodiazepines	0.000	0.999	0.001
Z73.6 Limitation of activities due to disability	0.000	0.999	0.001
Z73.5 Social role conflict, not elsewhere classified	0.000	0.999	0.001
Z73.4 Inadequate social skills, not elsewhere classified	0.000	0.999	0.001
Z73.2 Lack of relaxation and leisure	0.000	0.999	0.001
Z73.1 Accentuation of personality traits	0.000	0.999	0.001
Z73.0 Burn-out	0.000	0.999	0.001
C05 Malignant neoplasm of palate	0.000	0.999	0.001
H36.8 Other retinal disorders in diseases classified elsewhere	0.001	0.999	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.999	0.001
M66.59 Spontaneous rupture of unspecified tendon (Site unspecified)	0.000	0.999	0.001
M66.58 Spontaneous rupture of unspecified tendon (Other)	0.000	0.999	0.001
M66.56 Spontaneous rupture of unspecified tendon (Lower leg)	0.000	0.999	0.001
M66.55 Spontaneous rupture of unspecified tendon (Pelvic region and thigh)	0.000	0.999	0.001
M66.53 Spontaneous rupture of unspecified tendon (Forearm)	0.000	0.999	0.001
M66.51 Spontaneous rupture of unspecified tendon (Shoulder region)	0.000	0.999	0.001
M66.50 Spontaneous rupture of unspecified tendon (Multiple sites)	0.000	0.999	0.001
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.999	0.001
C06.9 Mouth, unspecified	0.000	0.999	0.001
S46.0 Injury of tendon of the rotator cuff of shoulder	0.001	0.999	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.001	0.999	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.000	0.999	0.001
M66.39 Spontaneous rupture of flexor tendons (Site unspecified)	0.000	0.999	0.001
M66.38 Spontaneous rupture of flexor tendons (Other)	0.000	0.999	0.001
M66.37 Spontaneous rupture of flexor tendons (Ankle and foot)	0.000	0.999	0.001
M66.35 Spontaneous rupture of flexor tendons (Pelvic region and thigh)	0.000	0.999	0.001
M66.32 Spontaneous rupture of flexor tendons (Upper arm)	0.000	0.999	0.001
M66.30 Spontaneous rupture of flexor tendons (Multiple sites)	0.000	0.999	0.001
M66.54 Spontaneous rupture of unspecified tendon (Hand)	0.000	0.999	0.001
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.999	0.001
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.999	0.000
C12 Malignant neoplasm of pyriform sinus	0.000	0.999	0.001
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.000	0.999	0.001
M66.57 Spontaneous rupture of unspecified tendon (Ankle and foot)	0.000	0.999	0.001
M67.47 Ganglion, ankle and foot	0.000	0.999	0.001
M70.46 Prepatellar bursitis-Lower Leg	0.000	0.999	0.001
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.999	0.001
Z30.3 Menstrual extraction	0.000	0.999	0.001
C10 Malignant neoplasm of oropharynx	0.000	0.999	0.001
M66.36 Spontaneous rupture of flexor tendons (Lower leg)	0.000	0.999	0.001
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.000	0.999	0.001
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.000	0.999	0.001
C00.9 Lip, unspecified	0.000	0.999	0.001
C00.8 Overlapping lesion of lip	0.000	0.999	0.001
C00.6 Commissure of lip	0.000	0.999	0.001
C00.5 Lip, unspecified, inner aspect	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations