TreeWAS – Variant ID: rs9914578

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
M17.9 Gonarthrosis, unspecified	1.000	0.000	0.000
M23 Internal derangement of knee	1.000	0.000	0.000
M17 Gonarthrosis [arthrosis of knee]	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
M15-M19 Arthrosis	0.999	0.001	0.000
M65-M68 Disorders of synovium and tendon	0.997	0.003	0.000
I50 Heart failure	0.995	0.005	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.994	0.006	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.994	0.006	0.000
I50.0 Congestive heart failure	0.994	0.006	0.000
M65 Synovitis and tenosynovitis	0.993	0.007	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.990	0.010	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.990	0.010	0.000
M23.3 Other meniscus derangements	0.990	0.010	0.000
I30-I52 Other forms of heart disease	0.986	0.014	0.000
I50.1 Left ventricular failure	0.984	0.016	0.000
I51 Complications and ill-defined descriptions of heart disease	0.984	0.016	0.000
M24 Other specific joint derangements	0.979	0.021	0.000
I47 Paroxysmal tachycardia	0.975	0.025	0.000
I51.8 Other ill-defined heart diseases	0.970	0.030	0.000
M80-M85 Disorders of bone density and structure	0.963	0.037	0.000
M86-M90 Other osteopathies	0.963	0.037	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.958	0.042	0.000
I47.1 Supraventricular tachycardia	0.953	0.047	0.000
M86 Osteomyelitis	0.947	0.053	0.000
I47.2 Ventricular tachycardia	0.943	0.057	0.000
M21 Other acquired deformities of limbs	0.936	0.064	0.000
M66 Spontaneous rupture of synovium and tendon	0.936	0.064	0.000
I49 Other cardiac arrhythmias	0.934	0.066	0.000
I51.9 Heart disease, unspecified	0.933	0.067	0.000
M81 Osteoporosis without pathological fracture	0.921	0.079	0.000
M24.1 Other articular cartilage disorders	0.919	0.081	0.000
I49.8 Other specified cardiac arrhythmias	0.910	0.090	0.000
M17.5 Other secondary gonarthrosis	0.909	0.091	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.896	0.104	0.000
M81.4 Drug-induced osteoporosis	0.896	0.104	0.000
M86.9 Osteomyelitis, unspecified	0.892	0.108	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.885	0.115	0.000
I50.9 Heart failure, unspecified	0.879	0.121	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.879	0.121	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.878	0.122	0.000
M86.6 Other chronic osteomyelitis	0.878	0.122	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.872	0.128	0.000
M17.0 Primary gonarthrosis, bilateral	0.867	0.133	0.000
I38 Endocarditis, valve unspecified	0.866	0.134	0.000
M17.1 Other primary gonarthrosis	0.862	0.138	0.000
M24.0 Loose body in joint	0.855	0.145	0.000
I51.7 Cardiomegaly	0.850	0.150	0.000
M66.2 Spontaneous rupture of extensor tendons	0.843	0.157	0.000
M23.1 Discoid meniscus (congenital)	0.840	0.160	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.836	0.164	0.000
M85 Other disorders of bone density and structure	0.835	0.165	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.832	0.168	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.829	0.171	0.000
M65.2 Calcific tendinitis	0.827	0.173	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.820	0.180	0.000
M21.0 Valgus deformity, not elsewhere classified	0.818	0.182	0.000
M15 Polyarthrosis	0.815	0.185	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.812	0.188	0.000
M23.4 Loose body in knee	0.809	0.191	0.000
M90 Osteopathies in diseases classified elsewhere	0.796	0.204	0.000
M23.8 Other internal derangements of knee	0.795	0.205	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.794	0.206	0.000
M91-M94 Chondropathies	0.793	0.207	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.792	0.208	0.000
M66.0 Rupture of popliteal cyst	0.790	0.210	0.000
M86.66 Other chronic osteomyelitis (Lower leg)	0.783	0.217	0.000
M00-M03 Infectious arthropathies	0.783	0.217	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.780	0.220	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.777	0.223	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.776	0.224	0.000
M65.1 Other infective (teno)synovitis	0.776	0.224	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.773	0.227	0.000
M24.07 Loose body in joint (Ankle and foot)	0.770	0.230	0.000
I33 Acute and subacute endocarditis	0.768	0.232	0.000
I49.9 Cardiac arrhythmia, unspecified	0.767	0.233	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.764	0.236	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.762	0.238	0.000
M24.5 Contracture of joint	0.761	0.239	0.000
M21.3 Wrist or foot drop (acquired)	0.753	0.247	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.752	0.248	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.751	0.249	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.750	0.249	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.747	0.253	0.000
M65.3 Trigger finger	0.743	0.257	0.000
M21.9 Acquired deformity of limb, unspecified	0.742	0.258	0.000
M84 Disorders of continuity of bone	0.742	0.258	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.741	0.259	0.000
I30 Acute pericarditis	0.740	0.260	0.000
M86.98 Osteomyelitis, unspecified (Other)	0.740	0.260	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.738	0.262	0.000
M86.1 Other acute osteomyelitis	0.734	0.266	0.000
M32 Systemic lupus erythematosus	0.730	0.270	0.000
I36 Nonrheumatic tricuspid valve disorders	0.727	0.273	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.726	0.274	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.725	0.275	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.724	0.276	0.000
M85.8 Other specified disorders of bone density and structure	0.724	0.276	0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.723	0.277	0.000
M21.6 Other acquired deformities of ankle and foot	0.719	0.281	0.000
I45 Other conduction disorders	0.718	0.282	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.717	0.283	0.000
M22 Disorders of patella	0.716	0.284	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.715	0.285	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.714	0.286	0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.713	0.287	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.713	0.287	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.712	0.288	0.000
M65.0 Abscess of tendon sheath	0.712	0.288	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.711	0.289	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.710	0.290	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.710	0.290	0.000
M23.37 Other meniscus derangements-Capsular lig	0.710	0.290	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.709	0.291	0.000
M65.21 Calcific tendinitis (Shoulder region)	0.709	0.291	0.000
I52 Other heart disorders in diseases classified elsewhere	0.707	0.293	0.000
I48 Atrial fibrillation and flutter	0.707	0.293	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.707	0.293	0.000
I41 Myocarditis in diseases classified elsewhere	0.707	0.293	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.707	0.293	0.000
I32 Pericarditis in diseases classified elsewhere	0.707	0.293	0.000
I49.0 Ventricular fibrillation and flutter	0.706	0.294	0.000
I51.5 Myocardial degeneration	0.705	0.295	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.705	0.295	0.000
M66.4 Spontaneous rupture of other tendons	0.705	0.295	0.000
M18 Arthrosis of first carpometacarpal joint	0.702	0.298	0.000
M24.9 Joint derangement, unspecified	0.702	0.298	0.000
M23.43 Loose body in knee-Med lig/oth men	0.699	0.301	0.000
I49.1 Atrial premature depolarisation	0.699	0.301	0.000
I51.4 Myocarditis, unspecified	0.697	0.303	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.694	0.306	0.000
M23.9 Internal derangement of knee, unspecified	0.692	0.307	0.000
M83 Adult osteomalacia	0.690	0.309	0.000
I40 Acute myocarditis	0.690	0.310	0.000
M90.1 Periostitis in other infectious diseases classified elsewhere	0.690	0.310	0.000
M81.9 Osteoporosis, unspecified	0.686	0.314	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.686	0.314	0.000
M33 Dermatopolymyositis	0.684	0.316	0.000
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)	0.683	0.317	0.000
I51.0 Cardiac septal defect, acquired	0.682	0.318	0.000
M15.9 Polyarthrosis, unspecified	0.681	0.319	0.000
M86.8 Other osteomyelitis	0.680	0.320	0.000
M86.5 Other chronic haematogenous osteomyelitis	0.679	0.321	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.679	0.321	0.000
M86.3 Chronic multifocal osteomyelitis	0.679	0.321	0.000
M86.2 Subacute osteomyelitis	0.679	0.321	0.000
M86.0 Acute haematogenous osteomyelitis	0.679	0.321	0.000
M23.0 Cystic meniscus	0.679	0.321	0.000
M66.3 Spontaneous rupture of flexor tendons	0.677	0.323	0.000
M60-M63 Disorders of muscles	0.675	0.325	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.675	0.325	0.000
M24.06 Loose body in joint-Lower leg	0.675	0.325	0.000
M30 Polyarteritis nodosa and related conditions	0.673	0.327	0.000
M88 Paget's disease of bone [osteitis deformans]	0.672	0.328	0.000
I45.1 Other and unspecified right bundle-branch block	0.672	0.328	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.671	0.329	0.000
M66.1 Rupture of synovium	0.671	0.329	0.000
M21.2 Flexion deformity	0.670	0.329	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.670	0.330	0.000
I49.2 Junctional premature depolarisation	0.669	0.330	0.000
M85.6 Other cyst of bone	0.669	0.331	0.000
I51.6 Cardiovascular disease, unspecified	0.668	0.331	0.000
M82 Osteoporosis in diseases classified elsewhere	0.665	0.335	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.663	0.337	0.000
M81.8 Other osteoporosis	0.660	0.340	0.000
M81.6 Localised osteoporosis [Lequesne]	0.660	0.340	0.000
M81.5 Idiopathic osteoporosis	0.660	0.340	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.660	0.340	0.000
M81.1 Postoophorectomy osteoporosis	0.660	0.340	0.000
M21.8 Other specified acquired deformities of limbs	0.660	0.340	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.659	0.341	0.000
M24.18 Other articular cartilage disorders (Other)	0.659	0.341	0.000
M24.14 Other articular cartilage disorders (Hand)	0.659	0.341	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.659	0.341	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.659	0.341	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.659	0.341	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.659	0.341	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.653	0.347	0.000
M24.2 Disorder of ligament	0.652	0.348	0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.650	0.350	0.000
M93 Other osteochondropathies	0.644	0.356	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.642	0.358	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.642	0.358	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.642	0.358	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.642	0.358	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.642	0.358	0.000
M81.48 Drug-induced osteoporosis (Other)	0.642	0.358	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.642	0.358	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.642	0.358	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.642	0.358	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.642	0.358	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.642	0.358	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.642	0.358	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.642	0.358	0.000
M81.98 Osteoporosis, unspecified (Other)	0.642	0.358	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.642	0.358	0.000
M86.93 Osteomyelitis, unspecified (Forearm)	0.640	0.360	0.000
M86.92 Osteomyelitis, unspecified (Upper arm)	0.640	0.360	0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.640	0.360	0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.640	0.360	0.000
M24.7 Protrusio acetabuli	0.638	0.362	0.000
M81.2 Osteoporosis of disuse	0.630	0.369	0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.630	0.370	0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.630	0.370	0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.630	0.370	0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.630	0.370	0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.630	0.370	0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.630	0.370	0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.630	0.370	0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.630	0.370	0.000
M86.69 Other chronic osteomyelitis (Site unspecified)	0.630	0.370	0.000
M86.68 Other chronic osteomyelitis (Other)	0.630	0.370	0.000
M86.64 Other chronic osteomyelitis (Hand)	0.630	0.370	0.000
M86.63 Other chronic osteomyelitis (Forearm)	0.630	0.370	0.000
M86.62 Other chronic osteomyelitis (Upper arm)	0.630	0.370	0.000
M86.61 Other chronic osteomyelitis (Shoulder region)	0.630	0.370	0.000
M86.60 Other chronic osteomyelitis (Multiple sites)	0.630	0.370	0.000
M31 Other necrotising vasculopathies	0.629	0.371	0.000
M24.52 Contracture of joint (Upper arm)	0.629	0.371	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.629	0.371	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.629	0.371	0.000
I47.0 Reentry ventricular arrhythmia	0.629	0.371	0.000
M23.5 Chronic instability of knee	0.627	0.372	0.000
I49.3 Ventricular premature depolarisation	0.627	0.373	0.000
M65.8 Other synovitis and tenosynovitis	0.627	0.373	0.000
I30.1 Infective pericarditis	0.627	0.373	0.000
M84.0 Malunion of fracture	0.624	0.376	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.622	0.378	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.621	0.379	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.620	0.380	0.000
I33.0 Acute and subacute infective endocarditis	0.618	0.382	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.617	0.382	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.617	0.383	0.000
M00 Pyogenic arthritis	0.616	0.384	0.000
M85.2 Hyperostosis of skull	0.614	0.386	0.000
M90.10 Periostitis in other infectious diseases classified elsewhere (Multiple sites)	0.613	0.387	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.613	0.387	0.000
M24.09 Loose body in joint (Site unspecified)	0.613	0.387	0.000
M24.08 Loose body in joint (Other)	0.613	0.387	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.613	0.387	0.000
M24.04 Loose body in joint (Hand)	0.613	0.387	0.000
M24.00 Loose body in joint (Multiple sites)	0.613	0.387	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.613	0.387	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.611	0.389	0.000
M21.4 Flat foot [pes planus] (acquired)	0.608	0.392	0.000
M15.4 Erosive (osteo)arthrosis	0.608	0.392	0.000
M81.0 Postmenopausal osteoporosis	0.605	0.394	0.000
M22.4 Chondromalacia patellae	0.605	0.395	0.000
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.604	0.396	0.000
M66.28 Spontaneous rupture of extensor tendons-Other	0.604	0.396	0.000
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.604	0.396	0.000
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.604	0.396	0.000
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.604	0.396	0.000
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.604	0.396	0.000
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.604	0.396	0.000
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.604	0.396	0.000
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.604	0.396	0.000
M17.3 Other posttraumatic gonarthrosis	0.604	0.396	0.000
M24.03 Loose body in joint (Forearm)	0.603	0.396	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.603	0.397	0.000
M94 Other disorders of cartilage	0.603	0.397	0.000
M24.01 Loose body in joint (Shoulder region)	0.602	0.398	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.602	0.398	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.602	0.398	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.602	0.398	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.602	0.398	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.602	0.398	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.602	0.398	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.602	0.398	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.602	0.398	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.602	0.398	0.000
M85.9 Disorder of bone density and structure, unspecified	0.599	0.401	0.000
M85.5 Aneurysmal bone cyst	0.599	0.401	0.000
M85.4 Solitary bone cyst	0.599	0.401	0.000
M85.3 Osteitis condensans	0.599	0.401	0.000
M85.1 Skeletal fluorosis	0.599	0.401	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.597	0.402	0.000
M15.3 Secondary multiple arthrosis	0.595	0.405	0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.594	0.406	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.594	0.406	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.594	0.406	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.594	0.406	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.594	0.406	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.594	0.406	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.594	0.406	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.594	0.406	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.594	0.406	0.000
M21.7 Unequal limb length (acquired)	0.594	0.406	0.000
M65.29 Calcific tendinitis (Site unspecified)	0.593	0.407	0.000
M65.28 Calcific tendinitis (Other)	0.593	0.407	0.000
M65.27 Calcific tendinitis (Ankle and foot)	0.593	0.407	0.000
M65.26 Calcific tendinitis (Lower leg)	0.593	0.407	0.000
M65.25 Calcific tendinitis (Pelvic region and thigh)	0.593	0.407	0.000
M65.24 Calcific tendinitis (Hand)	0.593	0.407	0.000
M65.23 Calcific tendinitis (Forearm)	0.593	0.407	0.000
M65.22 Calcific tendinitis (Upper arm)	0.593	0.407	0.000
M65.20 Calcific tendinitis (Multiple sites)	0.593	0.407	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.592	0.408	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.587	0.413	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.587	0.413	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.587	0.413	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.587	0.413	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.587	0.413	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.587	0.413	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.587	0.413	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.587	0.413	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.586	0.414	0.000
M15.99 Polyosteoarthritis, unspecified	0.585	0.415	0.000
M15.0 Primary generalised (osteo)arthrosis	0.584	0.416	0.000
M15.8 Other polyarthrosis	0.584	0.416	0.000
M22.8 Other disorders of patella	0.583	0.417	0.000
M24.51 Contracture of joint (Shoulder region)	0.582	0.418	0.000
M86.17 Other acute osteomyelitis (Ankle and foot)	0.580	0.420	0.000
M23.47 Loose body in knee-Capsular lig	0.580	0.420	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.580	0.420	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.580	0.420	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.580	0.420	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.580	0.420	0.000
M23.40 Loose body in knee-Mult sites	0.580	0.420	0.000
I45.2 Bifascicular block	0.580	0.420	0.000
M02 Reactive arthropathies	0.577	0.423	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.576	0.423	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.576	0.423	0.000
M24.6 Ankylosis of joint	0.572	0.428	0.000
M90.8 Osteopathy in other diseases classified elsewhere	0.571	0.429	0.000
M90.6 Osteitis deformans in neoplastic disease	0.571	0.429	0.000
M90.5 Osteonecrosis in other diseases classified elsewhere	0.571	0.429	0.000
M90.4 Osteonecrosis due to heamoglobinopathy	0.571	0.429	0.000
M90.3 Osteonecrosis in caisson disease	0.571	0.429	0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere	0.571	0.429	0.000
M90.0 Tuberculosis of bone	0.571	0.429	0.000
M40-M43 Deforming dorsopathies	0.571	0.429	0.000
M84.2 Delayed union of fracture	0.570	0.430	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.570	0.430	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.570	0.430	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.570	0.430	0.000
M21.1 Varus deformity, not elsewhere classified	0.570	0.430	0.000
I49.5 Sick sinus syndrome	0.569	0.431	0.000
M66.09 Rupture of popliteal cyst-Site unspec	0.567	0.433	0.000
M66.08 Rupture of popliteal cyst-Other	0.567	0.433	0.000
M66.07 Rupture of popliteal cyst-Ankle/foot	0.567	0.433	0.000
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.567	0.433	0.000
M66.04 Rupture of popliteal cyst-Hand	0.567	0.433	0.000
M66.03 Rupture of popliteal cyst-Forearm	0.567	0.433	0.000
M66.02 Rupture of popliteal cyst-Upper arm	0.567	0.433	0.000
M66.01 Rupture of popliteal cyst-Shldr region	0.567	0.433	0.000
M66.00 Rupture of popliteal cyst-Mult sites	0.567	0.433	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.565	0.435	0.000
M65.34 Trigger finger-Hand	0.564	0.436	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.563	0.437	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.563	0.437	0.000
I45.5 Other specified heart block	0.562	0.438	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.561	0.438	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.561	0.438	0.000
M24.56 Contracture of joint (Lower leg)	0.558	0.442	0.000
M80 Osteoporosis with pathological fracture	0.558	0.442	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.557	0.443	0.000
M36.3 Arthropathy in other blood disorders	0.557	0.443	0.000
M36.2 Haemophilic arthropathy	0.557	0.443	0.000
M36.1 Arthropathy in neoplastic disease	0.557	0.443	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.557	0.443	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.556	0.443	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.556	0.444	0.000
M65.19 Other infective (teno)synovitis (Site unspecified)	0.556	0.444	0.000
M65.18 Other infective (teno)synovitis (Other)	0.556	0.444	0.000
M65.17 Other infective (teno)synovitis (Ankle and foot)	0.556	0.444	0.000
M65.16 Other infective (teno)synovitis (Lower leg)	0.556	0.444	0.000
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)	0.556	0.444	0.000
M65.13 Other infective (teno)synovitis (Forearm)	0.556	0.444	0.000
M65.12 Other infective (teno)synovitis (Upper arm)	0.556	0.444	0.000
M65.11 Other infective (teno)synovitis (Shoulder region)	0.556	0.444	0.000
M65.10 Other infective (teno)synovitis (Multiple sites)	0.556	0.444	0.000
M23.46 Loose body in knee-O/unsp lat men	0.554	0.446	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.553	0.447	0.000
M23.49 Loose body in knee-Unspec lig/men	0.553	0.447	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.551	0.449	0.000
M21.24 Flexion deformity (Hand)	0.548	0.451	0.000
M84.3 Stress fracture, not elsewhere classified	0.546	0.454	0.000
M24.59 Contracture of joint (Site unspecified)	0.545	0.454	0.000
M24.58 Contracture of joint (Other)	0.545	0.454	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.545	0.454	0.000
M24.53 Contracture of joint (Forearm)	0.545	0.454	0.000
M24.50 Contracture of joint (Multiple sites)	0.545	0.454	0.000
M90.7 Fracture of bone in neoplastic disease	0.543	0.456	0.000
I45.8 Other specified conduction disorders	0.543	0.457	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.542	0.458	0.000
I33.9 Acute endocarditis, unspecified	0.541	0.458	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.540	0.460	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.540	0.460	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.540	0.460	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.540	0.460	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.540	0.460	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.540	0.460	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.540	0.460	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.540	0.460	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.540	0.460	0.000
M85.0 Fibrous dysplasia (monostotic)	0.539	0.461	0.000
M24.02 Loose body in joint (Upper arm)	0.539	0.461	0.000
M93.9 Osteochondropathy, unspecified	0.537	0.463	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.537	0.463	0.000
M34 Systemic sclerosis	0.536	0.464	0.000
M84.4 Pathological fracture, not elsewhere classified	0.535	0.465	0.000
I37 Pulmonary valve disorders	0.534	0.466	0.001
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.533	0.467	0.000
M65.39 Trigger finger-Site unspec	0.533	0.467	0.000
M65.38 Trigger finger-Other	0.533	0.467	0.000
M65.37 Trigger finger-Ankle/foot	0.533	0.467	0.000
M65.36 Trigger finger-Lower leg	0.533	0.467	0.000
M65.35 Trigger finger-Pelvic/thigh	0.533	0.467	0.000
M65.33 Trigger finger-Forearm	0.533	0.467	0.000
M65.32 Trigger finger-Upper arm	0.533	0.467	0.000
M65.31 Trigger finger-Shldr region	0.533	0.467	0.000
M65.30 Trigger finger-Mult sites	0.533	0.467	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.532	0.468	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.532	0.468	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.532	0.468	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.532	0.468	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.532	0.468	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.532	0.468	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.532	0.468	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.532	0.468	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.532	0.468	0.000
M84.9 Disorder of continuity of bone, unspecified	0.532	0.468	0.000
M84.8 Other disorders of continuity of bone	0.532	0.468	0.000
I30.8 Other forms of acute pericarditis	0.531	0.469	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.531	0.469	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.530	0.470	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.529	0.470	0.000
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.529	0.471	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.528	0.472	0.000
M89 Other disorders of bone	0.528	0.472	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.526	0.473	0.000
M86.19 Other acute osteomyelitis (Site unspecified)	0.526	0.474	0.000
M86.18 Other acute osteomyelitis (Other)	0.526	0.474	0.000
M86.16 Other acute osteomyelitis (Lower leg)	0.526	0.474	0.000
M86.15 Other acute osteomyelitis (Pelvic region and thigh)	0.526	0.474	0.000
M86.14 Other acute osteomyelitis (Hand)	0.526	0.474	0.000
M86.13 Other acute osteomyelitis (Forearm)	0.526	0.474	0.000
M86.12 Other acute osteomyelitis (Upper arm)	0.526	0.474	0.000
M86.11 Other acute osteomyelitis (Shoulder region)	0.526	0.474	0.000
M86.10 Other acute osteomyelitis (Multiple sites)	0.526	0.474	0.000
M87 Osteonecrosis	0.525	0.475	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.523	0.476	0.000
M32.8 Other forms of systemic lupus erythematosus	0.523	0.476	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.523	0.476	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.522	0.478	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.521	0.478	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.521	0.478	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.521	0.478	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.521	0.478	0.000
M88.8 Paget's disease of other bones	0.521	0.479	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.520	0.480	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.519	0.481	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.519	0.481	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.519	0.481	0.000
M66.47 Spontaneous rupture of other tendons (Ankle and foot)	0.517	0.483	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.515	0.485	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.515	0.485	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.515	0.485	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.515	0.485	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.515	0.485	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.515	0.485	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.515	0.485	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.515	0.485	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.515	0.485	0.000
I45.0 Right fascicular block	0.515	0.485	0.000
M85.66 Other cyst of bone (Lower leg)	0.515	0.485	0.000
M24.23 Disorder of ligament (Forearm)	0.515	0.485	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.514	0.486	0.000
M22.1 Recurrent subluxation of patella	0.513	0.487	0.000
M22.9 Disorder of patella, unspecified	0.513	0.487	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.513	0.487	0.000
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere	0.512	0.487	0.000
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere	0.512	0.487	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.510	0.490	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.510	0.490	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.510	0.490	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.510	0.490	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.510	0.490	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.510	0.490	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.510	0.490	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.510	0.490	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.510	0.490	0.000
M65.09 Abscess of tendon sheath (Site unspecified)	0.510	0.490	0.000
M65.08 Abscess of tendon sheath (Other)	0.510	0.490	0.000
M65.07 Abscess of tendon sheath (Ankle and foot)	0.510	0.490	0.000
M65.06 Abscess of tendon sheath (Lower leg)	0.510	0.490	0.000
M65.05 Abscess of tendon sheath (Pelvic region and thigh)	0.510	0.490	0.000
M65.04 Abscess of tendon sheath (Hand)	0.510	0.490	0.000
M65.03 Abscess of tendon sheath (Forearm)	0.510	0.490	0.000
M65.02 Abscess of tendon sheath (Upper arm)	0.510	0.490	0.000
M65.01 Abscess of tendon sheath (Shoulder region)	0.510	0.490	0.000
M65.00 Abscess of tendon sheath (Multiple sites)	0.510	0.490	0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.508	0.491	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.507	0.493	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.507	0.493	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.507	0.493	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.507	0.493	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.507	0.493	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations