TreeWAS – Variant ID: rs9933429

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G47.3 Sleep apnoea	0.730	0.270	0.000
G47 Sleep disorders	0.575	0.425	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.514	0.486	0.000
G47.4 Narcolepsy and cataplexy	0.477	0.523	0.000
G47.9 Sleep disorder, unspecified	0.424	0.576	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.421	0.579	0.000
G47.8 Other sleep disorders	0.420	0.580	0.000
G47.2 Disorders of the sleep-wake schedule	0.407	0.593	0.000
E86 Volume depletion	0.000	0.958	0.042
Z50.1 Other physical therapy	0.000	0.967	0.033
I46.0 Cardiac arrest with successful resuscitation	0.000	0.973	0.027
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.026	0.974	0.000
E24 Cushing's syndrome	0.025	0.975	0.000
E22 Hyperfunction of pituitary gland	0.024	0.976	0.000
E87.7 Fluid overload	0.000	0.976	0.024
E20-E35 Disorders of other endocrine glands	0.023	0.977	0.000
E24.0 Pituitary-dependent Cushing's disease	0.023	0.977	0.000
E24.9 Cushing's syndrome, unspecified	0.023	0.977	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.978	0.022
L71.9 Rosacea, unspecified	0.000	0.978	0.022
E70-E90 Metabolic disorders	0.000	0.978	0.022
E24.2 Drug-induced Cushing's syndrome	0.021	0.979	0.000
E27 Other disorders of adrenal gland	0.021	0.979	0.000
E87.2 Acidosis	0.000	0.979	0.021
E83.4 Disorders of magnesium metabolism	0.000	0.979	0.021
E83 Disorders of mineral metabolism	0.000	0.979	0.021
E27.4 Other and unspecified adrenocortical insufficiency	0.020	0.980	0.000
E87.0 Hyperosmolality and hypernatraemia	0.000	0.980	0.020
E29 Testicular dysfunction	0.019	0.981	0.000
E87.6 Hypokalaemia	0.000	0.981	0.019
E23 Hypofunction and other disorders of pituitary gland	0.018	0.982	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.982	0.018
E27.9 Disorder of adrenal gland, unspecified	0.018	0.982	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.018	0.982	0.000
E24.8 Other Cushing's syndrome	0.018	0.982	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.018	0.982	0.000
E24.3 Ectopic ACTH syndrome	0.018	0.982	0.000
E24.1 Nelson's syndrome	0.018	0.982	0.000
E31 Polyglandular dysfunction	0.018	0.982	0.000
E74 Other disorders of carbohydrate metabolism	0.000	0.983	0.017
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.000	0.983	0.017
E22.9 Hyperfunction of pituitary gland, unspecified	0.017	0.983	0.000
E22.8 Other hyperfunction of pituitary gland	0.017	0.983	0.000
E25 Adrenogenital disorders	0.017	0.983	0.000
E73 Lactose intolerance	0.000	0.983	0.017
E35 Disorders of endocrine glands in diseases classified elsewhere	0.017	0.983	0.000
E32 Diseases of thymus	0.017	0.983	0.000
E30 Disorders of puberty, not elsewhere classified	0.017	0.983	0.000
E20 Hypoparathyroidism	0.017	0.983	0.000
E87.3 Alkalosis	0.000	0.984	0.016
E87.4 Mixed disorder of acid-base balance	0.000	0.984	0.016
E22.1 Hyperprolactinaemia	0.016	0.984	0.000
E29.1 Testicular hypofunction	0.016	0.984	0.000
E84 Cystic fibrosis	0.000	0.984	0.016
E22.0 Acromegaly and pituitary gigantism	0.016	0.984	0.000
Z50 Care involving use of rehabilitation procedures	0.000	0.984	0.016
E23.2 Diabetes insipidus	0.016	0.984	0.000
E26 Hyperaldosteronism	0.016	0.984	0.000
E77 Disorders of glycoprotein metabolism	0.000	0.984	0.016
E76 Disorders of glycosaminoglycan metabolism	0.000	0.984	0.016
E72 Other disorders of amino-acid metabolism	0.000	0.984	0.016
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.984	0.016
E70 Disorders of aromatic amino-acid metabolism	0.000	0.984	0.016
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.984	0.016
E85 Amyloidosis	0.000	0.984	0.016
E21.0 Primary hyperparathyroidism	0.015	0.985	0.000
E27.5 Adrenomedullary hyperfunction	0.015	0.985	0.000
E27.0 Other adrenocortical overactivity	0.015	0.985	0.000
E27.8 Other specified disorders of adrenal gland	0.015	0.985	0.000
E79 Disorders of purine and pyrimidine metabolism	0.000	0.985	0.015
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.985	0.015
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.985	0.015
E83.8 Other disorders of mineral metabolism	0.000	0.985	0.015
E83.2 Disorders of zinc metabolism	0.000	0.985	0.015
E83.0 Disorders of copper metabolism	0.000	0.985	0.015
E21.5 Disorder of parathyroid gland, unspecified	0.015	0.985	0.000
E83.1 Disorders of iron metabolism	0.000	0.985	0.015
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.985	0.014
E27.3 Drug-induced adrenocortical insufficiency	0.014	0.986	0.000
E23.7 Disorder of pituitary gland, unspecified	0.014	0.986	0.000
E29.9 Testicular dysfunction, unspecified	0.014	0.986	0.000
E29.8 Other testicular dysfunction	0.014	0.986	0.000
E29.0 Testicular hyperfunction	0.014	0.986	0.000
E27.2 Addisonian crisis	0.014	0.986	0.000
E73.9 Lactose intolerance, unspecified	0.000	0.986	0.014
E31.0 Autoimmune polyglandular failure	0.013	0.986	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.013	0.986	0.000
E23.1 Drug-induced hypopituitarism	0.013	0.986	0.000
E21.4 Other specified disorders of parathyroid gland	0.013	0.987	0.000
E21.2 Other hyperparathyroidism	0.013	0.987	0.000
E23.6 Other disorders of pituitary gland	0.013	0.987	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.013	0.987	0.000
E31.9 Polyglandular dysfunction, unspecified	0.013	0.987	0.000
E31.8 Other polyglandular dysfunction	0.013	0.987	0.000
E31.1 Polyglandular hyperfunction	0.013	0.987	0.000
E85.3 Secondary systemic amyloidosis	0.000	0.987	0.013
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.987	0.013
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.987	0.013
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.987	0.013
E74.2 Disorders of galactose metabolism	0.000	0.987	0.013
E74.1 Disorders of fructose metabolism	0.000	0.987	0.013
E74.0 Glycogen storage disease	0.000	0.987	0.013
Z50.8 Care involving use of rehabilitation procedures	0.000	0.987	0.013
E25.9 Adrenogenital disorder, unspecified	0.012	0.987	0.000
E25.8 Other adrenogenital disorders	0.012	0.987	0.000
E73.8 Other lactose intolerance	0.000	0.987	0.012
E73.1 Secondary lactase deficiency	0.000	0.987	0.012
E73.0 Congenital lactase deficiency	0.000	0.987	0.012
Z50.4 Psychotherapy, not elsewhere classified	0.000	0.988	0.012
L71 Rosacea	0.000	0.988	0.012
E30.9 Disorder of puberty, unspecified	0.012	0.988	0.000
E30.8 Other disorders of puberty	0.012	0.988	0.000
E30.1 Precocious puberty	0.012	0.988	0.000
E30.0 Delayed puberty	0.012	0.988	0.000
E32.9 Disease of thymus, unspecified	0.012	0.988	0.000
E32.8 Other diseases of thymus	0.012	0.988	0.000
E32.1 Abscess of thymus	0.012	0.988	0.000
E32.0 Persistent hyperplasia of thymus	0.012	0.988	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.012	0.988	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.012	0.988	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.012	0.988	0.000
E28 Ovarian dysfunction	0.012	0.988	0.000
E84.9 Cystic fibrosis, unspecified	0.000	0.988	0.012
E20.8 Other hypoparathyroidism	0.012	0.988	0.000
E20.1 Pseudohypoparathyroidism	0.012	0.988	0.000
E20.0 Idiopathic hypoparathyroidism	0.012	0.988	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.012	0.988	0.000
E20.9 Hypoparathyroidism, unspecified	0.012	0.988	0.000
E34 Other endocrine disorders	0.012	0.988	0.000
E84.8 Cystic fibrosis with other manifestations	0.000	0.988	0.012
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.988	0.012
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.988	0.012
Z50.6 Orthoptic training	0.000	0.988	0.012
Z50.3 Drug rehabilitation	0.000	0.988	0.012
E26.9 Hyperaldosteronism, unspecified	0.011	0.988	0.000
E26.8 Other hyperaldosteronism	0.011	0.988	0.000
E26.1 Secondary hyperaldosteronism	0.011	0.988	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.988	0.011
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.988	0.011
E70.3 Albinism	0.000	0.988	0.011
E70.2 Disorders of tyrosine metabolism	0.000	0.988	0.011
E70.1 Other hyperphenylalaninaemias	0.000	0.988	0.011
E70.0 Classical phenylketonuria	0.000	0.988	0.011
E71.3 Disorders of fatty-acid metabolism	0.000	0.988	0.011
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.988	0.011
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.988	0.011
E71.0 Maple-syrup-urine disease	0.000	0.988	0.011
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.988	0.011
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.988	0.011
E72.5 Disorders of glycine metabolism	0.000	0.988	0.011
E72.4 Disorders of ornithine metabolism	0.000	0.988	0.011
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.988	0.011
E72.2 Disorders of urea cycle metabolism	0.000	0.988	0.011
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.988	0.011
E72.0 Disorders of amino-acid transport	0.000	0.988	0.011
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.988	0.011
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.988	0.011
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.988	0.011
E76.2 Other mucopolysaccharidoses	0.000	0.988	0.011
E76.1 Mucopolysaccharidosis, type II	0.000	0.988	0.011
E76.0 Mucopolysaccharidosis, type I	0.000	0.988	0.011
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.988	0.011
E77.8 Other disorders of glycoprotein metabolism	0.000	0.988	0.011
E77.1 Defects in glycoprotein degradation	0.000	0.988	0.011
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.988	0.011
E88 Other metabolic disorders	0.000	0.988	0.012
Z50.5 Speech therapy	0.000	0.989	0.011
E85.8 Other amyloidosis	0.000	0.989	0.011
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.989	0.011
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.989	0.011
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.989	0.011
E23.0 Hypopituitarism	0.011	0.989	0.000
E75.6 Lipid storage disorder, unspecified	0.000	0.989	0.011
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.989	0.011
E75.3 Sphingolipidosis, unspecified	0.000	0.989	0.011
E75.2 Other sphingolipidosis	0.000	0.989	0.011
E75.1 Other gangliosidosis	0.000	0.989	0.011
E75.0 GM2 gangliosidosis	0.000	0.989	0.011
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.989	0.011
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.989	0.011
E79.1 Lesch-Nyhan syndrome	0.000	0.989	0.011
E21.3 Hyperparathyroidism, unspecified	0.011	0.989	0.000
L71.1 Rhinophyma	0.000	0.989	0.011
E85.9 Amyloidosis, unspecified	0.000	0.989	0.010
E26.0 Primary hyperaldosteronism	0.010	0.990	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.990	0.010
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.990	0.010
E75.5 Other lipid storage disorders	0.000	0.990	0.010
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.990	0.010
E85.4 Organ-limited amyloidosis	0.000	0.990	0.010
Q50.4 Embryonic cyst of Fallopian tube	0.010	0.990	0.000
E27.1 Primary adrenocortical insufficiency	0.009	0.991	0.000
E88.2 Lipomatosis, not elsewhere classified	0.000	0.991	0.009
L71.8 Other rosacea	0.000	0.991	0.009
L71.0 Perioral dermatitis	0.000	0.991	0.009
E28.9 Ovarian dysfunction, unspecified	0.009	0.991	0.000
E28.8 Other ovarian dysfunction	0.009	0.991	0.000
E28.1 Androgen excess	0.009	0.991	0.000
E28.0 Oestrogen excess	0.009	0.991	0.000
E87.5 Hyperkalaemia	0.000	0.991	0.009
E88.8 Other specified metabolic disorders	0.000	0.991	0.009
E34.5 Androgen resistance syndrome	0.009	0.991	0.000
E34.4 Constitutional tall stature	0.009	0.991	0.000
E34.3 Short stature, not elsewhere classified	0.009	0.991	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.009	0.991	0.000
E34.1 Other hypersecretion of intestinal hormones	0.009	0.991	0.000
E28.3 Primary ovarian failure	0.009	0.991	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.009	0.991	0.000
E34.0 Carcinoid syndrome	0.008	0.991	0.000
E88.3 Tumour lysis syndrome	0.000	0.991	0.008
Z50.2 Alcohol rehabilitation	0.000	0.991	0.009
G40-G47 Episodic and paroxysmal disorders	0.008	0.992	0.000
E80.6 Other disorders of bilirubin metabolism	0.000	0.992	0.008
E88.9 Metabolic disorder, unspecified	0.000	0.992	0.008
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.992	0.008
E80.5 Crigler-Najjar syndrome	0.000	0.992	0.008
E80.3 Defects of catalase and peroxydase	0.000	0.992	0.008
E80.1 Porphyria cutanea tarda	0.000	0.992	0.008
E80.0 Hereditary erythropoietic porphyria	0.000	0.992	0.008
E80.2 Other porphyria	0.000	0.993	0.007
E34.9 Endocrine disorder, unspecified	0.007	0.993	0.000
I77.1 Stricture of artery	0.000	0.993	0.007
I46 Cardiac arrest	0.000	0.993	0.007
G41 Status epilepticus	0.007	0.993	0.000
M35.0 Sicca syndrome [Sjogren]	0.007	0.993	0.000
E34.8 Other specified endocrine disorders	0.006	0.993	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.993	0.006
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.000	0.994	0.006
G41.9 Status epilepticus, unspecified	0.006	0.994	0.000
R27.8 Other and unspecified lack of coordination	0.006	0.994	0.000
K22.2 Oesophageal obstruction	0.000	0.994	0.006
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.994	0.006
T40.4 Other synthetic narcotics	0.006	0.994	0.000
G44 Other headache syndromes	0.006	0.994	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.006	0.994	0.000
V23.4 Driver injured in traffic accident	0.000	0.994	0.006
S02.4 Fracture of malar and maxillary bones	0.005	0.994	0.000
E28.2 Polycystic ovarian syndrome	0.005	0.995	0.000
I46.1 Sudden cardiac death, so described	0.000	0.995	0.005
G41.8 Other status epilepticus	0.005	0.995	0.000
G41.2 Complex partial status epilepticus	0.005	0.995	0.000
G41.1 Petit mal status epilepticus	0.005	0.995	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.005	0.995	0.000
R16.1 Splenomegaly, not elsewhere classified	0.000	0.995	0.005
S32.10 Fracture of sacrum (closed)	0.000	0.995	0.005
T40.2 Other opioids	0.005	0.995	0.000
G41.0 Grand mal status epilepticus	0.005	0.995	0.000
Z50.0 Cardiac rehabilitation	0.000	0.995	0.005
Q50.5 Embryonic cyst of broad ligament	0.005	0.995	0.000
K60.3 Anal fistula	0.005	0.995	0.000
Z74.1 Need for assistance with personal care	0.000	0.995	0.005
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.000	0.995	0.005
G44.3 Chronic posttraumatic headache	0.005	0.995	0.000
E10.5 With peripheral circulatory complications	0.000	0.995	0.005
G44.0 Cluster headache syndrome	0.005	0.995	0.000
G44.1 Vascular headache, not elsewhere classified	0.004	0.995	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.995	0.005
U51.1 Previously admitted to a psychiatric hospital of the provider	0.004	0.996	0.000
S82.30 Fracture of lower end of tibia (closed)	0.004	0.996	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.004	0.996	0.000
Q50.3 Other congenital malformations of ovary	0.004	0.996	0.000
Q50.2 Congenital torsion of ovary	0.004	0.996	0.000
Q50.1 Developmental ovarian cyst	0.004	0.996	0.000
Q50.0 Congenital absence of ovary	0.004	0.996	0.000
T40.5 Cocaine	0.004	0.996	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.004	0.996	0.000
G44.2 Tension-type headache	0.004	0.996	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.004	0.996	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.004	0.996	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.996	0.004
S32.1 Fracture of sacrum	0.000	0.996	0.004
T40.6 Other and unspecified narcotics	0.004	0.996	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.004	0.996	0.000
E10.0 With coma	0.000	0.996	0.004
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.996	0.004
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.004	0.996	0.000
T40.8 Lysergide [LSD]	0.004	0.996	0.000
T40.7 Cannabis (derivatives)	0.004	0.996	0.000
T40.3 Methadone	0.004	0.996	0.000
T40.1 Heroin	0.004	0.996	0.000
T40.0 Opium	0.004	0.996	0.000
E10.8 With unspecified complications	0.000	0.996	0.004
D25.1 Intramural leiomyoma of uterus	0.000	0.996	0.004
S32.0 Fracture of lumbar vertebra	0.000	0.996	0.004
E10.3 With ophthalmic complications	0.000	0.996	0.004
E10.9 Without complications	0.000	0.996	0.004
C92.0 Acute myeloid leukaemia	0.000	0.996	0.004
S32 Fracture of lumbar spine and pelvis	0.000	0.996	0.003
E10.4 With neurological complications	0.000	0.997	0.003
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
E89.2 Postprocedural hypoparathyroidism	0.000	0.997	0.003
S32.7 Multiple fractures of lumbar spine and pelvis	0.000	0.997	0.003
K82.1 Hydrops of gallbladder	0.000	0.997	0.003
S02.20 Fracture of nasal bones (closed)	0.003	0.997	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.997	0.003
G46.8 Other vascular syndromes of brain in cerebrovascular diseases	0.003	0.997	0.000
G46.6 Pure sensory lacunar syndrome	0.003	0.997	0.000
G46.5 Pure motor lacunar syndrome	0.003	0.997	0.000
G46.2 Posterior cerebral artery syndrome	0.003	0.997	0.000
G46.1 Anterior cerebral artery syndrome	0.003	0.997	0.000
G46.0 Middle cerebral artery syndrome	0.003	0.997	0.000
R18 Ascites	0.000	0.997	0.003
S32.11 Fracture of sacrum (open)	0.000	0.997	0.003
G44.8 Other specified headache syndromes	0.003	0.997	0.000
K82.4 Cholesterolosis of gallbladder	0.000	0.997	0.003
S02.2 Fracture of nasal bones	0.003	0.997	0.000
E10.7 With multiple complications	0.000	0.997	0.003
Z74 Problems related to care-provider dependency	0.000	0.997	0.003
E83.5 Disorders of calcium metabolism	0.000	0.997	0.003
S02 Fracture of skull and facial bones	0.003	0.997	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.997	0.003
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.997	0.003
E89.5 Postprocedural testicular hypofunction	0.000	0.997	0.003
I46.9 Cardiac arrest, unspecified	0.000	0.997	0.003
G46.3 Brain stem stroke syndrome	0.003	0.997	0.001
U51 Admission status on psychiatric patients	0.003	0.997	0.000
R85.5 Abnormal microbiological findings	0.003	0.997	0.000
S32.01 Fracture of lumbar vertebra (open)	0.000	0.997	0.003
U51.0 Not Previously admitted to a psyciatric hospital	0.003	0.997	0.000
Z74.2 Need for assistance at home and no other household member able to render care	0.000	0.997	0.003
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
Z74.8 Other problems related to care-provider dependency	0.000	0.997	0.003
S02.9 Fracture of skull and facial bones, part unspecified	0.003	0.997	0.000
E10.2 With renal complications	0.000	0.997	0.003
M95.0 Acquired deformity of nose	0.003	0.997	0.000
M51.2 Other specified intervertebral disk displacement	0.003	0.997	0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.000	0.997	0.003
F99 Mental disorder, not otherwise specified	0.000	0.997	0.003
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.003	0.997	0.000
E89.4 Postprocedural ovarian failure	0.000	0.997	0.002
G46.4 Cerebellar stroke syndrome	0.002	0.997	0.001
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.000	0.997	0.003
S32.3 Fracture of ilium	0.000	0.997	0.003
M51.8 Other specified intervertebral disk disorders	0.003	0.997	0.000
S02.7 Multiple fractures involving skull and facial bones	0.003	0.997	0.000
S32.2 Fracture of coccyx	0.000	0.997	0.003
E10.6 With other specified complications	0.000	0.997	0.003
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.997	0.003
Z74.9 Problem related to care-provider dependency, unspecified	0.000	0.997	0.003
S02.5 Fracture of tooth	0.003	0.997	0.000
S02.21 Fracture of nasal bones (open)	0.003	0.997	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.997	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.997	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.003	0.997	0.000
T44.0 Anticholinesterase agents	0.003	0.997	0.000
E89.1 Postprocedural hypoinsulinaemia	0.001	0.997	0.002
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.000	0.997	0.003
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.997	0.002
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.997	0.003
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.003	0.997	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.003	0.997	0.000
H50.1 Divergent concomitant strabismus	0.003	0.997	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.997	0.000
Z43.2 Attention to ileostomy	0.000	0.997	0.003
K37 Unspecified appendicitis	0.000	0.997	0.003
E80.4 Gilbert's syndrome	0.000	0.997	0.002
G46.7 Other lacunar syndromes	0.002	0.997	0.001
Z74.3 Need for continuous supervision	0.000	0.997	0.002
E89.3 Postprocedural hypopituitarism	0.000	0.997	0.002
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.997	0.000
S02.3 Fracture of orbital floor	0.002	0.997	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.000	0.997	0.002
S32.5 Fracture of pubis	0.000	0.997	0.002
U51.2 Previously admitted to a psychiatric hospital of another provider	0.002	0.997	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.997	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.002	0.998	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.002	0.998	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.998	0.002
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.002	0.998	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.002	0.998	0.000
S32.4 Fracture of acetabulum	0.000	0.998	0.002
M25.06 Haemarthrosis (Lower leg)	0.002	0.998	0.000
H50.9 Strabismus, unspecified	0.002	0.998	0.000
S02.50 Fracture of tooth (closed)	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.002	0.998	0.000
S02.8 Fractures of other skull and facial bones	0.002	0.998	0.000
T45.2 Vitamins, not elsewhere classified	0.002	0.998	0.000
V23.9 Unspecified motorcycle rider injured in traffic accident	0.000	0.998	0.002
V23.5 Passenger injured in traffic accident	0.000	0.998	0.002
V23.3 Person injured while boarding or alighting	0.000	0.998	0.002
V23.2 Unspecified motorcycle rider injured in nontraffic accident	0.000	0.998	0.002
V23.1 Passenger injured in nontraffic accident	0.000	0.998	0.002
V23.0 Driver injured in nontraffic accident	0.000	0.998	0.002
S32.31 Fracture of ilium (open)	0.000	0.998	0.002
S32.30 Fracture of ilium (closed)	0.000	0.998	0.002
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.000	0.998	0.002
S02.71 Multiple fractures involving skull and facial bones (open)	0.002	0.998	0.000
S32.21 Fracture of coccyx (open)	0.000	0.998	0.002
S32.20 Fracture of coccyx (closed)	0.000	0.998	0.002
J86.9 Pyothorax without fistula	0.000	0.998	0.002
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
S02.51 Fracture of tooth (open)	0.002	0.998	0.000
S02.0 Fracture of vault of skull	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
T45.5 Anticoagulants	0.002	0.998	0.000
M41.86 Other forms of scoliosis (Lumbar region)	0.002	0.998	0.000
K82 Other diseases of gallbladder	0.000	0.998	0.002
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
R74.8 Abnormal levels of other serum enzymes	0.000	0.998	0.002
T47.4 Other laxatives	0.002	0.998	0.000
E10-E14 Diabetes mellitus	0.000	0.998	0.002
T47.0 Histamine H(2)-receptor antagonists	0.002	0.998	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.002	0.998	0.000
E10.1 With ketoacidosis	0.000	0.998	0.002
T50.6 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
M48.09 Spinal stenosis (Site unspecified)	0.002	0.998	0.000
S02.31 Fracture of orbital floor (open)	0.002	0.998	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.000	0.998	0.002
S32.51 Fracture of pubis (open)	0.000	0.998	0.002
S82.3 Fracture of lower end of tibia	0.002	0.998	0.000
Z51.8 Other specified medical care	0.000	0.998	0.002
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.998	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.998	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.998	0.000
T45.4 Iron and its compounds	0.002	0.998	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.998	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
T47.7 Emetics	0.002	0.998	0.000
T47.6 Antidiarrhoeal drugs	0.002	0.998	0.000
T47.5 Digestants	0.002	0.998	0.000
T47.3 Saline and osmotic laxatives	0.002	0.998	0.000
T47.2 Stimulant laxatives	0.002	0.998	0.000
X23.9 Unspecified place	0.000	0.998	0.002
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.002	0.998	0.000
T50.8 Diagnostic agents	0.002	0.998	0.000
N48.8 Other specified disorders of penis	0.000	0.998	0.002
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
S32.41 Fracture of acetabulum (open)	0.000	0.998	0.002
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.998	0.002
S02.1 Fracture of base of skull	0.002	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
S02.30 Fracture of orbital floor (closed)	0.002	0.998	0.000
K05.1 Chronic gingivitis	0.002	0.998	0.000
S02.6 Fracture of mandible	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.002	0.998	0.000
H16.0 Corneal ulcer	0.002	0.998	0.000
T48.5 Anti-common-cold drugs	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
S02.81 Fractures of other skull and facial bones (open)	0.002	0.998	0.000
V23.99 Motorcycle rider injured in collision with car, pick-up truck or van, Unspecified motorcycle rider injured in traffic accident, Unspecified place	0.000	0.998	0.002
T48.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
E11.0 With coma	0.000	0.998	0.002
T37.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.998	0.000
E11.5 With peripheral circulatory complications	0.000	0.998	0.002
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
T48.4 Expectorants	0.002	0.998	0.000
T48.3 Antitussives	0.002	0.998	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
T48.0 Oxytocic drugs	0.002	0.998	0.000
M43.02 Spondylolysis (Cervical region)	0.002	0.998	0.000
N64.9 Disorder of breast, unspecified	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
T37.5 Antiviral drugs	0.002	0.998	0.000
T37.4 Anthelminthics	0.002	0.998	0.000
T37.3 Other antiprotozoal drugs	0.002	0.998	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
T37.1 Antimycobacterial drugs	0.002	0.998	0.000
T37.0 Sulphonamides	0.002	0.998	0.000
M51 Other intervertebral disk disorders	0.002	0.998	0.000
S02.01 Fracture of vault of skull (open)	0.002	0.998	0.000
E11.1 With ketoacidosis	0.000	0.998	0.002
T41.5 Therapeutic gases	0.002	0.998	0.000
T41.4 Anaesthetic, unspecified	0.002	0.998	0.000
T41.3 Local anaesthetics	0.002	0.998	0.000
T41.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
T41.1 Intravenous anaesthetics	0.002	0.998	0.000
T41.0 Inhaled anaesthetics	0.002	0.998	0.000
T49.9 Topical agent, unspecified	0.002	0.998	0.000
T49.8 Other topical agents	0.002	0.998	0.000
T49.7 Dental drugs, topically applied	0.002	0.998	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
T49.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
T49.3 Emollients, demulcents and protectants	0.002	0.998	0.000
T49.2 Local astringents and local detergents	0.002	0.998	0.000
T49.1 Antipruritics	0.002	0.998	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
T50.7 Analeptics and opioid receptor antagonists	0.002	0.998	0.000
T50.5 Appetite depressants	0.002	0.998	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
T50.1 Loop [high-ceiling] diuretics	0.002	0.998	0.000
T50.0 Mineralocorticoids and their antagonists	0.002	0.998	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.998	0.002
K82.0 Obstruction of gallbladder	0.000	0.998	0.002
T39.1 4-Aminophenol derivatives	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations