TreeWAS – Variant ID: rs9969804

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I08.0 Disorders of both mitral and aortic valves	0.031	0.969	0.000
D11.0 Parotid gland	0.000	0.985	0.015
N47 Redundant prepuce, phimosis and paraphimosis	0.000	0.989	0.011
R25.1 Tremor, unspecified	0.000	0.991	0.009
D61.9 Aplastic anaemia, unspecified	0.009	0.991	0.000
I08 Multiple valve diseases	0.008	0.992	0.000
F10.1 Harmful use	0.000	0.992	0.008
I08.1 Disorders of both mitral and tricuspid valves	0.008	0.992	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.008	0.992	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.007	0.993	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.993	0.007
T46.1 Calcium-channel blockers	0.007	0.993	0.000
F03 Unspecified dementia	0.000	0.993	0.007
T40.2 Other opioids	0.007	0.993	0.000
F00 Dementia in Alzheimer's disease	0.000	0.994	0.006
D46.9 Myelodysplastic syndrome, unspecified	0.006	0.994	0.000
N05.9 Unspecified	0.006	0.994	0.000
O47.0 False labour before 37 completed weeks of gestation	0.000	0.994	0.006
T36-T50 Poisoning by drugs, medicaments and biological substances	0.006	0.994	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.006	0.994	0.000
I08.9 Multiple valve disease, unspecified	0.006	0.994	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.006	0.994	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.006	0.994	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.000	0.994	0.006
E83.1 Disorders of iron metabolism	0.000	0.994	0.006
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.006	0.994	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.005	0.994	0.000
T46.7 Peripheral vasodilators	0.005	0.994	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.005	0.994	0.000
F10.3 Withdrawal state	0.000	0.994	0.006
N05.1 Focal and segmental glomerular lesions	0.005	0.994	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.000	0.995	0.005
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.995	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.005	0.995	0.000
N05 Unspecified nephritic syndrome	0.005	0.995	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.995	0.005
T50.9 Other and unspecified drugs, medicaments and biological substances	0.005	0.995	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.005	0.995	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.005	0.995	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.005	0.995	0.000
I08.8 Other multiple valve diseases	0.005	0.995	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.005	0.995	0.000
D46 Myelodysplastic syndromes	0.005	0.995	0.000
T42.1 Iminostilbenes	0.005	0.995	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.005	0.995	0.000
T36 Poisoning by systemic antibiotics	0.005	0.995	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.005	0.995	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.005	0.995	0.000
Y54.3 Benzothiadiazine derivatives	0.000	0.995	0.005
F00.0 Dementia in Alzheimer's disease with early onset	0.000	0.995	0.005
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.005	0.995	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.005	0.995	0.000
Y54.5 Other diuretics	0.000	0.995	0.005
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.005	0.995	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.005	0.995	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.995	0.005
T40.3 Methadone	0.005	0.995	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.005	0.995	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.000	0.995	0.005
T41 Poisoning by anaesthetics and therapeutic gases	0.005	0.995	0.000
D46.2 Refractory anaemia with excess of blasts	0.005	0.995	0.000
E11.5 With peripheral circulatory complications	0.005	0.995	0.000
T42.0 Hydantoin derivatives	0.005	0.995	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.004	0.995	0.000
T40.1 Heroin	0.004	0.995	0.000
T50.1 Loop [high-ceiling] diuretics	0.004	0.996	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.004	0.996	0.000
M50.0 Cervical disk disorder with myelopathy	0.004	0.996	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.004	0.996	0.000
T40.8 Lysergide [LSD]	0.004	0.996	0.000
T40.7 Cannabis (derivatives)	0.004	0.996	0.000
T40.0 Opium	0.004	0.996	0.000
T42.3 Barbiturates	0.004	0.996	0.000
D46.1 Refractory anaemia with sideroblasts	0.004	0.996	0.000
T48.5 Anti-common-cold drugs	0.004	0.996	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.000	0.996	0.004
D61 Other aplastic anaemias	0.004	0.996	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.004	0.996	0.000
T50.7 Analeptics and opioid receptor antagonists	0.004	0.996	0.000
T50.5 Appetite depressants	0.004	0.996	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.004	0.996	0.000
T50.0 Mineralocorticoids and their antagonists	0.004	0.996	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.004	0.996	0.000
D46.7 Other myelodysplastic syndromes	0.004	0.996	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.004	0.996	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.004	0.996	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.004	0.996	0.000
T50.4 Drugs affecting uric acid metabolism	0.004	0.996	0.000
F02 Dementia in other diseases classified elsewhere	0.000	0.996	0.004
I78.1 Naevus, nonneoplastic	0.004	0.996	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.004	0.996	0.000
T42.2 Succinimides and oxazolidinediones	0.004	0.996	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.000	0.996	0.004
D46.4 Refractory anaemia, unspecified	0.004	0.996	0.000
F07.2 Postconcussional syndrome	0.000	0.996	0.004
N05.6 Dense deposit disease	0.004	0.996	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.004	0.996	0.000
N05.0 Minor glomerular abnormality	0.004	0.996	0.000
T36.4 Tetracyclines	0.004	0.996	0.000
F09 Unspecified organic or symptomatic mental disorder	0.000	0.996	0.004
T50.6 Antidotes and chelating agents, not elsewhere classified	0.004	0.996	0.000
T38.1 Thyroid hormones and substitutes	0.004	0.996	0.000
T47.0 Histamine H(2)-receptor antagonists	0.004	0.996	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.004	0.996	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.004	0.996	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.004	0.996	0.000
T48.4 Expectorants	0.004	0.996	0.000
T48.3 Antitussives	0.004	0.996	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.004	0.996	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.004	0.996	0.000
T48.0 Oxytocic drugs	0.004	0.996	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.004	0.996	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.004	0.996	0.000
T45.0 Antiallergic and antiemetic drugs	0.004	0.996	0.000
Z98.0 Intestinal bypass and anastomosis status	0.000	0.996	0.004
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.004	0.996	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.004	0.996	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.004	0.996	0.000
T47.2 Stimulant laxatives	0.004	0.996	0.000
T36.8 Other systemic antibiotics	0.004	0.996	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.000	0.996	0.004
N05.8 Other	0.004	0.996	0.000
N05.2 Diffuse membranous glomerulonephritis	0.004	0.996	0.000
T50.8 Diagnostic agents	0.004	0.996	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.996	0.004
T38.8 Other and unspecified hormones and their synthetic substitutes	0.004	0.996	0.000
Y45.1 Salicylates	0.000	0.996	0.004
F07.0 Organic personality disorder	0.000	0.996	0.004
T36.9 Systemic antibiotic, unspecified	0.004	0.996	0.000
T36.7 Antifungal antibiotics, systemically used	0.004	0.996	0.000
T36.6 Rifamycins	0.004	0.996	0.000
T36.5 Aminoglycosides	0.004	0.996	0.000
T36.2 Chloramphenicol group	0.004	0.996	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.004	0.996	0.000
T37.5 Antiviral drugs	0.004	0.996	0.000
T37.4 Anthelminthics	0.004	0.996	0.000
T37.3 Other antiprotozoal drugs	0.004	0.996	0.000
T37.1 Antimycobacterial drugs	0.004	0.996	0.000
T37.0 Sulphonamides	0.004	0.996	0.000
T40.6 Other and unspecified narcotics	0.004	0.996	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.004	0.996	0.000
T45.8 Other primarily systemic and haematological agents	0.004	0.996	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.004	0.996	0.000
T45.6 Fibrinolysis-affecting drugs	0.004	0.996	0.000
T45.4 Iron and its compounds	0.004	0.996	0.000
T45.3 Enzymes, not elsewhere classified	0.004	0.996	0.000
T38.9 Other and unspecified hormone antagonists	0.004	0.996	0.000
T38.7 Androgens and anabolic congeners	0.004	0.996	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.004	0.996	0.000
T38.5 Other oestrogens and progestogens	0.004	0.996	0.000
T38.4 Oral contraceptives	0.004	0.996	0.000
T38.2 Antithyroid drugs	0.004	0.996	0.000
T38.0 Glucocorticoids and synthetic analogues	0.004	0.996	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.004	0.996	0.000
T40.5 Cocaine	0.004	0.996	0.000
T47.6 Antidiarrhoeal drugs	0.004	0.996	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.004	0.996	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.004	0.996	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.004	0.996	0.000
T44.0 Anticholinesterase agents	0.004	0.996	0.000
T45.2 Vitamins, not elsewhere classified	0.004	0.996	0.000
T47.4 Other laxatives	0.004	0.996	0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.000	0.996	0.004
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.996	0.004
F07.1 Postencephalitic syndrome	0.000	0.996	0.004
T37.8 Other specified systemic anti-infectives and antiparasitics	0.003	0.996	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.003	0.996	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.003	0.996	0.000
T47.7 Emetics	0.003	0.996	0.000
T47.5 Digestants	0.003	0.996	0.000
T47.3 Saline and osmotic laxatives	0.003	0.996	0.000
G95.2 Cord compression, unspecified	0.004	0.996	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.004	0.996	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.000	0.996	0.004
T41.5 Therapeutic gases	0.003	0.996	0.000
T41.4 Anaesthetic, unspecified	0.003	0.996	0.000
T41.3 Local anaesthetics	0.003	0.996	0.000
T41.2 Other and unspecified general anaesthetics	0.003	0.996	0.000
T41.1 Intravenous anaesthetics	0.003	0.996	0.000
T41.0 Inhaled anaesthetics	0.003	0.996	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.000	0.996	0.004
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.003	0.996	0.000
T36.3 Macrolides	0.003	0.996	0.000
T45.5 Anticoagulants	0.003	0.996	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.996	0.000
F02.3 Dementia in Parkinson's disease	0.000	0.996	0.003
D61.0 Constitutional aplastic anaemia	0.003	0.996	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.003	0.996	0.000
D11 Benign neoplasm of major salivary glands	0.000	0.997	0.003
C78.1 Secondary malignant neoplasm of mediastinum	0.003	0.997	0.000
F05.1 Delirium superimposed on dementia	0.000	0.997	0.003
Z83.3 Family history of diabetes mellitus	0.003	0.997	0.000
Y54.9 Mineral salts, not elsewhere classified	0.000	0.997	0.003
Y54.6 Electrolytic, caloric and water-balance agents	0.000	0.997	0.003
Y54.2 Carbonic-anhydrase inhibitors	0.000	0.997	0.003
Y54.0 Mineralocorticoids	0.000	0.997	0.003
Y54.7 Agents affecting calcification	0.000	0.997	0.003
Y54.4 Loop [high-ceiling] diuretics	0.000	0.997	0.003
D61.8 Other specified aplastic anaemias	0.003	0.997	0.000
D61.3 Idiopathic aplastic anaemia	0.003	0.997	0.000
D61.2 Aplastic anaemia due to other external agents	0.003	0.997	0.000
T49.9 Topical agent, unspecified	0.003	0.997	0.000
T49.8 Other topical agents	0.003	0.997	0.000
T49.7 Dental drugs, topically applied	0.003	0.997	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.003	0.997	0.000
T49.5 Ophthalmological drugs and preparations	0.003	0.997	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.997	0.000
T49.3 Emollients, demulcents and protectants	0.003	0.997	0.000
T49.2 Local astringents and local detergents	0.003	0.997	0.000
T49.1 Antipruritics	0.003	0.997	0.000
Y54.8 Agents affecting uric acid metabolism	0.000	0.997	0.003
F01 Vascular dementia	0.000	0.997	0.003
F10 Mental and behavioural disorders due to use of alcohol	0.000	0.997	0.003
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.000	0.997	0.003
F02.2 Dementia in Huntington's disease	0.000	0.997	0.003
F02.1 Dementia in Creutzfeldt-Jakob disease	0.000	0.997	0.003
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.000	0.997	0.003
T36.0 Penicillins	0.003	0.997	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.997	0.003
F02.0 Dementia in Pick's disease	0.000	0.997	0.003
T40.4 Other synthetic narcotics	0.003	0.997	0.000
D61.1 Drug-induced aplastic anaemia	0.003	0.997	0.000
I05-I09 Chronic rheumatic heart diseases	0.003	0.997	0.000
F05.0 Delirium not superimposed on dementia, so described	0.000	0.997	0.003
J43.9 Emphysema, unspecified	0.000	0.997	0.003
C80.0 Malignant neoplasm, primary site unknown, so stated	0.003	0.997	0.000
F06.3 Organic mood [affective] disorders	0.000	0.997	0.003
F02.8 Dementia in other specified diseases classified elsewhere	0.000	0.997	0.003
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.997	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.000	0.997	0.003
F06.5 Organic dissociative disorder	0.000	0.997	0.003
F06.4 Organic anxiety disorder	0.000	0.997	0.003
F06.2 Organic delusional [schizophrenia-like] disorder	0.000	0.997	0.003
F06.1 Organic catatonic disorder	0.000	0.997	0.003
F06.0 Organic hallucinosis	0.000	0.997	0.003
F10.5 Psychotic disorder	0.000	0.997	0.003
Y84.2 Radiological procedure and radiotherapy	0.003	0.997	0.000
H21.8 Other specified disorders of iris and ciliary body	0.000	0.997	0.003
O34.2 Maternal care due to uterine scar from previous surgery	0.003	0.997	0.000
F10.6 Amnesic syndrome	0.000	0.997	0.003
I06 Rheumatic aortic valve diseases	0.003	0.997	0.000
H44.0 Purulent endophthalmitis	0.000	0.997	0.003
M23.30 Other meniscus derangements (Multiple sites)	0.003	0.997	0.000
F01.8 Other vascular dementia	0.000	0.997	0.003
F01.3 Mixed cortical and subcortical vascular dementia	0.000	0.997	0.003
F01.2 Subcortical vascular dementia	0.000	0.997	0.003
F01.0 Vascular dementia of acute onset	0.000	0.997	0.003
F10.8 Other mental and behavioural disorders	0.000	0.997	0.003
A49.1 Streptococcal infection, unspecified	0.000	0.997	0.003
F10.7 Residual and late-onset psychotic disorder	0.000	0.997	0.002
I44.3 Other and unspecified atrioventricular block	0.003	0.997	0.000
I05 Rheumatic mitral valve diseases	0.003	0.997	0.000
J32.8 Other chronic sinusitis	0.000	0.997	0.003
F01.1 Multi-infarct dementia	0.000	0.998	0.002
X59.2 School, other institution and public administrative area	0.000	0.998	0.002
I06.9 Rheumatic aortic valve disease, unspecified	0.002	0.998	0.000
I06.0 Rheumatic aortic stenosis	0.002	0.998	0.000
R26.3 Immobility	0.000	0.998	0.002
T47.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
R25 Abnormal involuntary movements	0.000	0.998	0.002
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.002	0.998	0.000
H33.2 Serous retinal detachment	0.002	0.998	0.000
I06.1 Rheumatic aortic insufficiency	0.002	0.998	0.000
O21.0 Mild hyperemesis gravidarum	0.000	0.998	0.002
C78.2 Secondary malignant neoplasm of pleura	0.002	0.998	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.002	0.998	0.000
G37 Other demyelinating diseases of central nervous system	0.002	0.998	0.000
M24.07 Loose body in joint (Ankle and foot)	0.000	0.998	0.002
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
I06.8 Other rheumatic aortic valve diseases	0.002	0.998	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.002	0.998	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.002	0.998	0.000
H33.5 Other retinal detachments	0.002	0.998	0.000
I09 Other rheumatic heart diseases	0.002	0.998	0.000
I05.2 Mitral stenosis with insufficiency	0.002	0.998	0.000
D11.7 Other major salivary glands	0.000	0.998	0.002
F22.0 Delusional disorder	0.000	0.998	0.002
I05.8 Other mitral valve diseases	0.002	0.998	0.000
Z49.1 Extracorporeal dialysis	0.002	0.998	0.000
L60.8 Other nail disorders	0.000	0.998	0.002
L73.2 Hidradenitis suppurativa	0.002	0.998	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
I05.0 Mitral stenosis	0.002	0.998	0.000
A49.8 Other bacterial infections of unspecified site	0.000	0.998	0.002
G47.8 Other sleep disorders	0.002	0.998	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.000	0.998	0.002
D59.9 Acquired haemolytic anaemia, unspecified	0.002	0.998	0.000
X59 Exposure to unspecified factor	0.000	0.998	0.002
D11.9 Major salivary gland, unspecified	0.000	0.998	0.002
X59.3 Sports and athletics area	0.000	0.998	0.002
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.000	0.998	0.002
F10.4 Withdrawal state with delirium	0.000	0.998	0.002
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
F01.9 Vascular dementia, unspecified	0.000	0.998	0.002
Z98.8 Other specified postsurgical states	0.000	0.998	0.002
L60.9 Nail disorder, unspecified	0.000	0.998	0.002
I05.9 Mitral valve disease, unspecified	0.002	0.998	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.000	0.998	0.002
F10.9 Unspecified mental and behavioural disorder	0.000	0.998	0.002
M66.0 Rupture of popliteal cyst	0.000	0.998	0.002
R25.0 Abnormal head movements	0.000	0.998	0.002
T43.5 Other and unspecified antipsychotics and neuroleptics	0.002	0.998	0.000
S01.9 Open wound of head, part unspecified	0.000	0.998	0.002
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
G37.5 Concentric sclerosis [Balo]	0.002	0.998	0.000
G37.4 Subacute necrotising myelitis	0.002	0.998	0.000
G37.2 Central pontine myelinolysis	0.002	0.998	0.000
G37.1 Central demyelination of corpus callosum	0.002	0.998	0.000
G37.0 Diffuse sclerosis	0.002	0.998	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.002	0.998	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.002	0.998	0.000
Z71.9 Counselling, unspecified	0.002	0.998	0.000
S82.20 Fracture of shaft of tibia (closed)	0.000	0.998	0.002
F05.8 Other delirium	0.001	0.998	0.001
I42.1 Obstructive hypertrophic cardiomyopathy	0.002	0.998	0.000
S01.2 Open wound of nose	0.000	0.998	0.002
I09.8 Other specified rheumatic heart diseases	0.002	0.998	0.000
I09.2 Chronic rheumatic pericarditis	0.002	0.998	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.002	0.998	0.000
I09.0 Rheumatic myocarditis	0.002	0.998	0.000
T39.4 Antirheumatics, not elsewhere classified	0.002	0.998	0.000
T39.2 Pyrazolone derivatives	0.002	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.998	0.002
D59.1 Other autoimmune haemolytic anaemias	0.002	0.998	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.002	0.998	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.002	0.998	0.000
K76.8 Other specified diseases of liver	0.002	0.998	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.002	0.998	0.000
F05.9 Delirium, unspecified	0.000	0.998	0.002
T43.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
X59.4 Street and highway	0.000	0.998	0.002
I07 Rheumatic tricuspid valve diseases	0.002	0.998	0.000
C32.9 Larynx, unspecified	0.002	0.998	0.000
H44.1 Other endophthalmitis	0.000	0.998	0.002
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
C80 Malignant neoplasm without specification of site	0.002	0.998	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.000	0.998	0.002
R25.3 Fasciculation	0.000	0.998	0.002
X59.9 Unspecified place	0.000	0.998	0.002
X59.8 Other specified place	0.000	0.998	0.002
X59.0 Home	0.000	0.998	0.002
X59.7 Farm	0.000	0.998	0.002
X59.6 Industrial and construction area	0.000	0.998	0.002
X59.5 Trade and service area	0.000	0.998	0.002
X59.1 Residential institution	0.000	0.998	0.002
Z75.5 Holiday relief care	0.002	0.998	0.000
D59 Acquired haemolytic anaemia	0.002	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.000	0.998	0.002
X58.9 Unspecified place	0.000	0.998	0.002
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.002	0.998	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.000	0.998	0.002
T43.9 Psychotropic drug, unspecified	0.002	0.998	0.000
M66.09 Rupture of popliteal cyst-Site unspec	0.000	0.998	0.002
M66.08 Rupture of popliteal cyst-Other	0.000	0.998	0.002
M66.07 Rupture of popliteal cyst-Ankle/foot	0.000	0.998	0.002
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.000	0.998	0.002
M66.04 Rupture of popliteal cyst-Hand	0.000	0.998	0.002
M66.03 Rupture of popliteal cyst-Forearm	0.000	0.998	0.002
M66.02 Rupture of popliteal cyst-Upper arm	0.000	0.998	0.002
M66.01 Rupture of popliteal cyst-Shldr region	0.000	0.998	0.002
M66.00 Rupture of popliteal cyst-Mult sites	0.000	0.998	0.002
J92.0 Pleural plaque with presence of asbestos	0.000	0.998	0.002
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.998	0.002
Y45.8 Other analgesics and antipyretics	0.000	0.998	0.002
F06.7 Mild cognitive disorder	0.000	0.998	0.002
L60.2 Onychogryphosis	0.000	0.998	0.002
B59 Pneumocystosis	0.002	0.998	0.000
H21 Other disorders of iris and ciliary body	0.000	0.998	0.002
X58 Exposure to other specified factors	0.000	0.998	0.002
D59.4 Other nonautoimmune haemolytic anaemias	0.002	0.998	0.000
A40.8 Other streptococcal septicaemia	0.000	0.998	0.002
H21.2 Degeneration of iris and ciliary body	0.000	0.998	0.002
I09.9 Rheumatic heart disease, unspecified	0.001	0.998	0.000
M20.1 Hallux valgus (acquired)	0.000	0.998	0.002
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.002	0.998	0.000
E83.4 Disorders of magnesium metabolism	0.000	0.998	0.002
S01.7 Multiple open wounds of head	0.000	0.998	0.002
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.001	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
H21.0 Hyphaema	0.000	0.998	0.002
K55.2 Angiodysplasia of colon	0.002	0.998	0.000
X58.3 Sports and athletics area	0.000	0.998	0.002
A49 Bacterial infection of unspecified site	0.000	0.998	0.002
C80.9 Malignant neoplasm, unspecified	0.002	0.998	0.000
H01.0 Blepharitis	0.002	0.998	0.000
I07.9 Tricuspid valve disease, unspecified	0.001	0.998	0.000
I07.8 Other tricuspid valve diseases	0.001	0.998	0.000
I07.2 Tricuspid stenosis with insufficiency	0.001	0.998	0.000
I07.0 Tricuspid stenosis	0.001	0.998	0.000
K11.9 Disease of salivary gland, unspecified	0.000	0.998	0.002
I05.1 Rheumatic mitral insufficiency	0.001	0.998	0.000
J17.3 Pneumonia in parasitic diseases	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.001	0.998	0.000
X59.09 Exposure to unspecified factor causing fracture; Unspecified place;	0.000	0.998	0.001
X59.88 Exposure to unspecified factor; Other specified places ;While engaged in other specified activities	0.000	0.998	0.001
X59.99 Exposure to unspecified factor causing other and unspecified injury, Unspecified place	0.000	0.998	0.001
D59.8 Other acquired haemolytic anaemias	0.001	0.998	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.001	0.998	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.001	0.998	0.000
D59.3 Haemolytic-uraemic syndrome	0.001	0.998	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.001	0.998	0.000
H21.4 Pupillary membranes	0.000	0.998	0.001
J94.2 Haemothorax	0.000	0.998	0.002
O71.7 Obstetric haematoma of pelvis	0.000	0.998	0.002
D59.0 Drug-induced autoimmune haemolytic anaemia	0.001	0.998	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.998	0.002
W13.9 Unspecified place	0.000	0.998	0.002
R26 Abnormalities of gait and mobility	0.000	0.998	0.002
D23.0 Skin of lip	0.000	0.998	0.002
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.000	0.998	0.002
X58.2 School, other institution and public administrative area	0.000	0.998	0.001
L60 Nail disorders	0.000	0.998	0.002
A49.2 Haemophilus influenzae infection, unspecified	0.000	0.999	0.001
C41.0 Bones of skull and face	0.000	0.999	0.001
C78.7 Secondary malignant neoplasm of liver	0.001	0.999	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.000	0.999	0.001
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.001	0.999	0.001
O66.0 Obstructed labour due to shoulder dystocia	0.000	0.999	0.001
X58.8 Other specified place	0.000	0.999	0.001
X58.0 Home	0.000	0.999	0.001
X58.7 Farm	0.000	0.999	0.001
X58.6 Industrial and construction area	0.000	0.999	0.001
X58.5 Trade and service area	0.000	0.999	0.001
X58.4 Street and highway	0.000	0.999	0.001
X58.1 Residential institution	0.000	0.999	0.001
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.999	0.001
H21.9 Disorder of iris and ciliary body, unspecified	0.000	0.999	0.001
Y52.3 Coronary vasodilators, not elsewhere classified	0.000	0.999	0.001
H44 Disorders of globe	0.000	0.999	0.001
C78.4 Secondary malignant neoplasm of small intestine	0.001	0.999	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.000	0.999	0.001
A49.3 Mycoplasma infection, unspecified	0.000	0.999	0.001
F20.5 Residual schizophrenia	0.000	0.999	0.001
Y52.7 Peripheral vasodilators	0.000	0.999	0.001
Z87.8 Personal history of other specified conditions	0.000	0.999	0.001
I78 Diseases of capillaries	0.001	0.999	0.000
Y52 Agents primarily affecting the cardiovascular system	0.000	0.999	0.001
Y45.4 Antirheumatics	0.000	0.999	0.001
X58-X59 Accidental exposure to other and unspecified factors	0.000	0.999	0.001
F22 Persistent delusional disorders	0.000	0.999	0.001
D58.9 Hereditary haemolytic anaemia, unspecified	0.001	0.999	0.000
G61.8 Other inflammatory polyneuropathies	0.000	0.999	0.001
H05.8 Other disorders of orbit	0.001	0.999	0.000
R26.1 Paralytic gait	0.000	0.999	0.001
O20 Haemorrhage in early pregnancy	0.000	0.999	0.001
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.000	0.999	0.001
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.000	0.999	0.001
C83.5 Lymphoblastic (diffuse)	0.001	0.999	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.001	0.999	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.000	0.999	0.001
H44.9 Disorder of globe, unspecified	0.000	0.999	0.001
L60.5 Yellow nail syndrome	0.000	0.999	0.001
L60.4 Beau's lines	0.000	0.999	0.001
N36.2 Urethral caruncle	0.000	0.999	0.001
E83 Disorders of mineral metabolism	0.000	0.999	0.001
M81.98 Osteoporosis, unspecified (Other)	0.000	0.999	0.001
X58.01 Exposure to other specified factors: Home: While engaged in leisure activity	0.000	0.999	0.001
X58.89 Exposure to other specified factors: Other specified places: During unspecified activity	0.000	0.999	0.001
G06.0 Intracranial abscess and granuloma	0.000	0.999	0.001
K61.3 Ischiorectal abscess	0.001	0.999	0.000
Y45.2 Propionic acid derivatives	0.000	0.999	0.001
S82.40 Fracture of fibula alone (closed)	0.001	0.999	0.000
H44.6 Retained (old) intraocular foreign body, magnetic	0.000	0.999	0.001
H44.3 Other degenerative disorders of globe	0.000	0.999	0.001
Y52.1 Calcium-channel blockers	0.000	0.999	0.001
Y56.3 Emollients, demulcents and protectants	0.000	0.999	0.001
C83 Diffuse non-Hodgkin's lymphoma	0.001	0.999	0.000
C25.7 Other parts of pancreas	0.001	0.999	0.000
C41.9 Bone and articular cartilage, unspecified	0.000	0.999	0.001
G24.9 Dystonia, unspecified	0.001	0.999	0.000
K38.1 Appendicular concretions	0.000	0.999	0.001
O03.9 Complete or unspecified, without complication	0.000	0.999	0.001
Y52.8 Antivaricose drugs, including sclerosing agents	0.000	0.999	0.001
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.001	0.999	0.000
C41.4 Pelvic bones, sacrum and coccyx	0.000	0.999	0.001
C83.7 Burkitt's tumour	0.001	0.999	0.000
G61.0 Guillain-Barre syndrome	0.000	0.999	0.001
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.000	0.999	0.001
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.999	0.001
S12.70 Multiple fractures of cervical spine (closed)	0.000	0.999	0.001
D58.0 Hereditary spherocytosis	0.001	0.999	0.000
F22.8 Other persistent delusional disorders	0.000	0.999	0.001
H35.0 Background retinopathy and retinal vascular changes	0.001	0.999	0.000
Q27.3 Peripheral arteriovenous malformation	0.000	0.999	0.001
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.999	0.001
J36 Peritonsillar abscess	0.001	0.999	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.001	0.999	0.000
O21.2 Late vomiting of pregnancy	0.000	0.999	0.001
S01.5 Open wound of lip and oral cavity	0.000	0.999	0.001
T43.3 Phenothiazine antipsychotics and neuroleptics	0.001	0.999	0.000
Y56.9 Topical agent, unspecified	0.000	0.999	0.001
Y56.8 Other topical agents	0.000	0.999	0.001
Y56.7 Dental drugs, topically applied	0.000	0.999	0.001
Y56.6 Otorhinolaryngological drugs and preparations	0.000	0.999	0.001
Y56.5 Ophthalmological drugs and preparations	0.000	0.999	0.001
Y56.2 Local astringents and local detergents	0.000	0.999	0.001
Y56.1 Antipruritics	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations