TreeWAS – Variant ID: rs9977253

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O26.9 Pregnancy-related condition, unspecified	0.000	0.934	0.066
O26 Maternal care for other conditions predominantly related to pregnancy	0.000	0.946	0.054
O26.2 Pregnancy care of habitual aborter	0.000	0.950	0.050
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.000	0.952	0.048
O26.8 Other specified pregnancy-related conditions	0.000	0.956	0.044
O26.4 Herpes gestationis	0.000	0.961	0.039
O26.1 Low weight gain in pregnancy	0.000	0.961	0.039
O26.5 Maternal hypotension syndrome	0.000	0.961	0.038
O26.0 Excessive weight gain in pregnancy	0.000	0.962	0.038
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.000	0.963	0.037
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.000	0.971	0.029
I49.9 Cardiac arrhythmia, unspecified	0.018	0.982	0.000
Z29.2 Other prophylactic chemotherapy	0.000	0.983	0.017
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.015	0.985	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.015	0.985	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.014	0.986	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.014	0.986	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.013	0.987	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.013	0.987	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.012	0.988	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.012	0.988	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.000	0.989	0.011
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.011	0.989	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.011	0.989	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.010	0.990	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.010	0.990	0.000
H40.0 Glaucoma suspect	0.000	0.990	0.010
Z29 Need for other prophylactic measures	0.000	0.991	0.009
N21.0 Calculus in bladder	0.000	0.991	0.009
O21 Excessive vomiting in pregnancy	0.000	0.991	0.009
O28 Abnormal findings on antenatal screening of mother	0.000	0.991	0.009
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.000	0.991	0.009
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.991	0.009
Z29.1 Prophylactic immunotherapy	0.000	0.991	0.008
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.008	0.992	0.000
M84 Disorders of continuity of bone	0.008	0.992	0.000
O29 Complications of anaesthesia during pregnancy	0.000	0.992	0.008
O25 Malnutrition in pregnancy	0.000	0.992	0.008
T78.4 Allergy, unspecified	0.000	0.992	0.008
K51.2 Ulcerative (chronic) proctitis	0.008	0.992	0.000
Z29.0 Isolation	0.000	0.992	0.008
O22 Venous complications in pregnancy	0.000	0.992	0.007
T78.3 Angioneurotic oedema	0.000	0.993	0.007
C16.9 Stomach, unspecified	0.007	0.993	0.000
O21.9 Vomiting of pregnancy, unspecified	0.000	0.993	0.007
O24 Diabetes mellitus in pregnancy	0.000	0.993	0.007
C16.2 Body of stomach	0.007	0.993	0.000
O21.8 Other vomiting complicating pregnancy	0.000	0.993	0.007
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.000	0.993	0.007
Z29.9 Prophylactic measure, unspecified	0.000	0.993	0.007
M84.0 Malunion of fracture	0.007	0.993	0.000
O23 Infections of genito-urinary tract in pregnancy	0.000	0.993	0.007
M84.2 Delayed union of fracture	0.007	0.993	0.000
C16 Malignant neoplasm of stomach	0.007	0.993	0.000
T78 Adverse effects, not elsewhere classified	0.000	0.993	0.007
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.000	0.993	0.007
M84.8 Other disorders of continuity of bone	0.007	0.993	0.000
M84.03 Malunion of fracture (Forearm)	0.007	0.993	0.000
C16.5 Lesser curvature of stomach, unspecified	0.007	0.993	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.000	0.993	0.006
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.000	0.993	0.006
O28.4 Abnormal radiological finding on antenatal screening of mother	0.000	0.993	0.006
O28.2 Abnormal cytological finding on antenatal screening of mother	0.000	0.993	0.006
O28.0 Abnormal haematological finding on antenatal screening of mother	0.000	0.993	0.006
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.000	0.994	0.006
O21.2 Late vomiting of pregnancy	0.000	0.994	0.006
T78.2 Anaphylactic shock, unspecified	0.000	0.994	0.006
M84.9 Disorder of continuity of bone, unspecified	0.006	0.994	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.000	0.994	0.006
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.000	0.994	0.006
O29.8 Other complications of anaesthesia during pregnancy	0.000	0.994	0.006
O29.6 Failed or difficult intubation during pregnancy	0.000	0.994	0.006
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.000	0.994	0.006
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.000	0.994	0.006
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.000	0.994	0.006
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.000	0.994	0.006
O29.1 Cardiac complications of anaesthesia during pregnancy	0.000	0.994	0.006
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.000	0.994	0.006
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.000	0.994	0.006
C16.6 Greater curvature of stomach, unspecified	0.006	0.994	0.000
C22.0 Liver cell carcinoma	0.000	0.994	0.006
C16.4 Pylorus	0.006	0.994	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.006	0.994	0.000
O23.0 Infections of kidney in pregnancy	0.000	0.994	0.006
M84.01 Malunion of fracture (Shoulder region)	0.006	0.994	0.000
M84.3 Stress fracture, not elsewhere classified	0.006	0.994	0.000
T78.9 Adverse effect, unspecified	0.000	0.994	0.006
M84.04 Malunion of fracture (Hand)	0.006	0.994	0.000
M84.22 Delayed union of fracture (Upper arm)	0.006	0.994	0.000
O22.9 Venous complication in pregnancy, unspecified	0.000	0.994	0.005
O22.8 Other venous complications in pregnancy	0.000	0.994	0.005
O22.5 Cerebral venous thrombosis in pregnancy	0.000	0.994	0.005
O22.2 Superficial thrombophlebitis in pregnancy	0.000	0.994	0.005
M84.26 Delayed union of fracture (Lower leg)	0.005	0.994	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.000	0.995	0.005
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.000	0.995	0.005
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.000	0.995	0.005
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.995	0.005
O22.1 Genital varices in pregnancy	0.000	0.995	0.005
J69.0 Pneumonitis due to food and vomit	0.005	0.995	0.000
M84.08 Malunion of fracture (Other)	0.005	0.995	0.000
C16.8 Overlapping lesion of stomach	0.005	0.995	0.000
M84.09 Malunion of fracture (Site unspecified)	0.005	0.995	0.000
M84.00 Malunion of fracture (Multiple sites)	0.005	0.995	0.000
M84.02 Malunion of fracture (Upper arm)	0.005	0.995	0.000
O22.4 Haemorrhoids in pregnancy	0.000	0.995	0.005
O23.3 Infections of other parts of urinary tract in pregnancy	0.000	0.995	0.005
O23.2 Infections of urethra in pregnancy	0.000	0.995	0.005
O23.1 Infections of bladder in pregnancy	0.000	0.995	0.005
K27 Peptic ulcer, site unspecified	0.005	0.995	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.005	0.995	0.000
M84.28 Delayed union of fracture (Other)	0.005	0.995	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.005	0.995	0.000
M84.24 Delayed union of fracture (Hand)	0.005	0.995	0.000
M84.23 Delayed union of fracture (Forearm)	0.005	0.995	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.005	0.995	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.005	0.995	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.005	0.995	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.000	0.995	0.005
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.005	0.995	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.005	0.995	0.000
M84.88 Other disorders of continuity of bone (Other)	0.005	0.995	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.005	0.995	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.005	0.995	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.005	0.995	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.005	0.995	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.005	0.995	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.005	0.995	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.995	0.005
O21.0 Mild hyperemesis gravidarum	0.000	0.995	0.005
O24.9 Diabetes mellitus in pregnancy, unspecified	0.000	0.995	0.005
T78.8 Other adverse effects, not elsewhere classified	0.000	0.995	0.005
S32.0 Fracture of lumbar vertebra	0.000	0.995	0.005
C16.1 Fundus of stomach	0.005	0.995	0.000
Z29.8 Other specified prophylactic measures	0.000	0.995	0.005
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.004	0.995	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.004	0.995	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.004	0.995	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.004	0.995	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.004	0.995	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.004	0.995	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.004	0.995	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.004	0.995	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.004	0.995	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.004	0.995	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.004	0.995	0.000
C22.9 Liver, unspecified	0.000	0.995	0.005
Z43.3 Attention to colostomy	0.000	0.995	0.005
M84.4 Pathological fracture, not elsewhere classified	0.004	0.995	0.000
K27.3 Acute without haemorrhage or perforation	0.004	0.995	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.995	0.005
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.995	0.004
A04.7 Enterocolitis due to Clostridium difficile	0.000	0.996	0.004
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.004	0.996	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.004	0.996	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.004	0.996	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.004	0.996	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.004	0.996	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.004	0.996	0.000
C16.3 Pyloric antrum	0.004	0.996	0.000
N80.8 Other endometriosis	0.000	0.996	0.004
K27.6 Chronic or unspecified with both haemorrhage and perforation	0.004	0.996	0.000
K27.5 Chronic or unspecified with perforation	0.004	0.996	0.000
K27.2 Acute with both haemorrhage and perforation	0.004	0.996	0.000
K27.1 Acute with perforation	0.004	0.996	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
M84.06 Malunion of fracture (Lower leg)	0.004	0.996	0.000
K27.0 Acute with haemorrhage	0.004	0.996	0.000
K27.7 Chronic without haemorrhage or perforation	0.004	0.996	0.000
S32.01 Fracture of lumbar vertebra (open)	0.000	0.996	0.004
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.003	0.996	0.000
C22.1 Intrahepatic bile duct carcinoma	0.000	0.996	0.004
O23.4 Unspecified infection of urinary tract in pregnancy	0.000	0.996	0.003
D35.2 Pituitary gland	0.000	0.996	0.004
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.996	0.004
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.003	0.996	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.003	0.996	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.003	0.996	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.003	0.996	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.003	0.996	0.000
H73.8 Other specified disorders of tympanic membrane	0.004	0.996	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.003	0.996	0.000
C22.7 Other specified carcinomas of liver	0.000	0.996	0.003
C22.4 Other sarcomas of liver	0.000	0.996	0.003
C22.3 Angiosarcoma of liver	0.000	0.996	0.003
C22.2 Hepatoblastoma	0.000	0.996	0.003
K27.4 Chronic or unspecified with haemorrhage	0.003	0.997	0.000
G20 Parkinson's disease	0.003	0.997	0.000
O23.5 Infections of the genital tract in pregnancy	0.000	0.997	0.003
S42.00 Fracture of clavicle (closed)	0.003	0.997	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.003	0.997	0.000
E23.0 Hypopituitarism	0.000	0.997	0.003
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
S51.9 Open wound of forearm, part unspecified	0.003	0.997	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
C16.0 Cardia	0.003	0.997	0.000
K51 Ulcerative colitis	0.003	0.997	0.000
J69 Pneumonitis due to solids and liquids	0.003	0.997	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.003	0.997	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.003	0.997	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.003	0.997	0.000
K51.4 Pseudopolyposis of colon	0.003	0.997	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O20 Haemorrhage in early pregnancy	0.000	0.997	0.003
M24.24 Disorder of ligament (Hand)	0.003	0.997	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.003	0.997	0.000
O43.1 Malformation of placenta	0.003	0.997	0.000
N21 Calculus of lower urinary tract	0.000	0.997	0.003
T78.1 Other adverse food reactions, not elsewhere classified	0.001	0.997	0.002
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
E10.4 With neurological complications	0.000	0.997	0.003
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.003	0.997	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
J69.8 Pneumonitis due to other solids and liquids	0.002	0.997	0.000
Z39.1 Care and examination of lactating mother	0.003	0.997	0.000
H73 Other disorders of tympanic membrane	0.003	0.997	0.000
S51.0 Open wound of elbow	0.003	0.997	0.000
X23.9 Unspecified place	0.000	0.997	0.003
S42.0 Fracture of clavicle	0.003	0.997	0.000
C77.9 Lymph node, unspecified	0.000	0.998	0.002
F05.9 Delirium, unspecified	0.000	0.998	0.002
J69.1 Pneumonitis due to oils and essences	0.002	0.998	0.000
D41.0 Kidney	0.000	0.998	0.002
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.000	0.998	0.002
S42.40 Fracture of lower end of humerus (closed)	0.002	0.998	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.998	0.002
K51.0 Ulcerative (chronic) enterocolitis	0.002	0.998	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.002	0.998	0.000
N21.1 Calculus in urethra	0.000	0.998	0.002
S51 Open wound of forearm	0.002	0.998	0.000
H73.1 Chronic myringitis	0.002	0.998	0.000
I44.1 Atrioventricular block, second degree	0.002	0.998	0.000
H73.0 Acute myringitis	0.002	0.998	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Z00.0 General medical examination	0.002	0.998	0.000
S42.4 Fracture of lower end of humerus	0.002	0.998	0.000
S42.01 Fracture of clavicle (open)	0.002	0.998	0.000
A40.9 Streptococcal septicaemia, unspecified	0.002	0.998	0.000
F20.0 Paranoid schizophrenia	0.000	0.998	0.002
C24.0 Extrahepatic bile duct	0.000	0.998	0.002
N21.9 Calculus of lower urinary tract, unspecified	0.000	0.998	0.002
K01.1 Impacted teeth	0.002	0.998	0.000
S13.4 Sprain and strain of cervical spine	0.002	0.998	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.002	0.998	0.000
S62.50 Fracture of thumb (closed)	0.000	0.998	0.002
N05.9 Unspecified	0.000	0.998	0.002
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.002	0.998	0.000
T63.4 Venom of other arthropods	0.000	0.998	0.002
S32 Fracture of lumbar spine and pelvis	0.000	0.998	0.002
X23 Contact with hornets, wasps and bees	0.000	0.998	0.002
I60.8 Other subarachnoid haemorrhage	0.000	0.998	0.002
K51.9 Ulcerative colitis, unspecified	0.002	0.998	0.000
R47.0 Dysphasia and aphasia	0.002	0.998	0.000
G63.2 Diabetic polyneuropathy	0.000	0.998	0.002
S42.41 Fracture of lower end of humerus (open)	0.002	0.998	0.000
X23.0 Home	0.000	0.998	0.002
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.002	0.998	0.000
M24.28 Disorder of ligament (Other)	0.002	0.998	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
N90.4 Leukoplakia of vulva	0.000	0.998	0.002
S27.0 Traumatic pneumothorax	0.002	0.998	0.000
S81.8 Open wound of other parts of lower leg	0.002	0.998	0.000
X23.8 Other specified place	0.000	0.998	0.002
M24.26 Disorder of ligament (Lower leg)	0.002	0.998	0.000
D41.4 Bladder	0.000	0.998	0.002
E23.6 Other disorders of pituitary gland	0.000	0.998	0.002
M24.2 Disorder of ligament	0.002	0.998	0.000
S32.1 Fracture of sacrum	0.000	0.998	0.002
M25.54 Pain in joint (Hand)	0.000	0.998	0.002
S51.8 Open wound of other parts of forearm	0.002	0.998	0.000
S42 Fracture of shoulder and upper arm	0.002	0.998	0.000
S82.10 Fracture of upper end of tibia (closed)	0.002	0.998	0.000
S32.3 Fracture of ilium	0.000	0.998	0.002
S49.8 Other specified injuries of shoulder and upper arm	0.002	0.998	0.000
G21 Secondary Parkinsonism	0.002	0.998	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.998	0.002
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.002	0.998	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.002	0.998	0.000
S49.7 Multiple injuries of shoulder and upper arm	0.002	0.998	0.000
I60 Subarachnoid haemorrhage	0.000	0.998	0.002
S32.10 Fracture of sacrum (closed)	0.000	0.998	0.002
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.002	0.998	0.000
F52.2 Failure of genital response	0.002	0.998	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.002	0.998	0.000
G24.5 Blepharospasm	0.002	0.998	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.002	0.998	0.000
R44.1 Visual hallucinations	0.002	0.998	0.000
X23.7 Farm	0.000	0.998	0.002
X23.6 Industrial and construction area	0.000	0.998	0.002
X23.5 Trade and service area	0.000	0.998	0.002
X23.4 Street and highway	0.000	0.998	0.002
X23.3 Sports and athletics area	0.000	0.998	0.002
X23.2 School, other institution and public administrative area	0.000	0.998	0.002
X23.1 Residential institution	0.000	0.998	0.002
I49 Other cardiac arrhythmias	0.002	0.998	0.000
G20-G26 Extrapyramidal and movement disorders	0.002	0.998	0.000
N21.8 Other lower urinary tract calculus	0.000	0.998	0.001
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.002	0.998	0.000
S32.30 Fracture of ilium (closed)	0.000	0.998	0.002
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.002	0.998	0.000
G21.0 Malignant neuroleptic syndrome	0.002	0.998	0.000
S51.7 Multiple open wounds of forearm	0.002	0.998	0.000
G23 Other degenerative diseases of basal ganglia	0.002	0.998	0.000
S92.40 Fracture of great toe (closed)	0.002	0.998	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.002	0.998	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.000	0.998	0.002
S32.2 Fracture of coccyx	0.000	0.998	0.002
M81.98 Osteoporosis, unspecified (Other)	0.000	0.998	0.002
C67.6 Ureteric orifice	0.000	0.998	0.002
G21.9 Secondary Parkinsonism, unspecified	0.002	0.998	0.000
O32.0 Maternal care for unstable lie	0.002	0.998	0.000
O20.8 Other haemorrhage in early pregnancy	0.000	0.998	0.001
R44.3 Hallucinations, unspecified	0.002	0.998	0.000
M24.54 Contracture of joint (Hand)	0.002	0.998	0.000
S32.11 Fracture of sacrum (open)	0.000	0.998	0.001
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.998	0.002
K51.5 Mucosal proctocolitis	0.001	0.998	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.000	0.998	0.002
S46.2 Injury of muscle and tendon of other parts of biceps	0.002	0.998	0.000
M24.29 Disorder of ligament (Site unspecified)	0.001	0.998	0.000
M24.22 Disorder of ligament (Upper arm)	0.001	0.998	0.000
M24.20 Disorder of ligament (Multiple sites)	0.001	0.998	0.000
A40.1 Septicaemia due to streptococcus, group B	0.002	0.998	0.000
C50.0 Nipple and areola	0.000	0.998	0.002
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.998	0.002
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.002	0.998	0.000
S32.31 Fracture of ilium (open)	0.000	0.998	0.001
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.001	0.998	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.998	0.001
E23.1 Drug-induced hypopituitarism	0.000	0.998	0.001
G21.8 Other secondary Parkinsonism	0.001	0.998	0.000
G21.3 Postencephalitic Parkinsonism	0.001	0.998	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.001	0.998	0.000
O20.0 Threatened abortion	0.000	0.998	0.002
S32.4 Fracture of acetabulum	0.000	0.998	0.002
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.002	0.998	0.000
A40 Streptococcal septicaemia	0.002	0.998	0.000
M10.96 Gout, unspecified (Lower leg)	0.000	0.998	0.002
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.998	0.001
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.998	0.001
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.001	0.998	0.000
A40.0 Septicaemia due to streptococcus, group A	0.001	0.998	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.998	0.001
S40-S49 Injuries to the shoulder and upper arm	0.002	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.001	0.998	0.000
A40.8 Other streptococcal septicaemia	0.001	0.998	0.000
G21.4 Vascular parkinsonism	0.001	0.998	0.000
I49.5 Sick sinus syndrome	0.002	0.998	0.000
I84.6 Residual haemorrhoidal skin tags	0.002	0.998	0.000
K04.7 Periapical abscess without sinus	0.002	0.998	0.000
N34.2 Other urethritis	0.002	0.998	0.000
Z39 Postpartum care and examination	0.002	0.998	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.001	0.998	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
E23.7 Disorder of pituitary gland, unspecified	0.000	0.998	0.001
I49.2 Junctional premature depolarisation	0.001	0.998	0.000
G24 Dystonia	0.001	0.998	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.001	0.998	0.000
G22 Parkinsonism in diseases classified elsewhere	0.001	0.998	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.001	0.998	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.001	0.998	0.000
G23.3 Multiple system atrophy, cerebellar type	0.001	0.998	0.000
G23.2 Striatonigral degeneration	0.001	0.998	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.001	0.998	0.000
G23.0 Hallervorden-Spatz disease	0.001	0.998	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.998	0.001
T82.0 Mechanical complication of heart valve prosthesis	0.001	0.998	0.000
M80-M85 Disorders of bone density and structure	0.002	0.998	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
S32.21 Fracture of coccyx (open)	0.000	0.999	0.001
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.000	0.999	0.001
I49.8 Other specified cardiac arrhythmias	0.001	0.999	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.001	0.999	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.999	0.001
L98.0 Pyogenic granuloma	0.001	0.999	0.000
N89.9 Noninflammatory disorder of vagina, unspecified	0.001	0.999	0.000
R44.2 Other hallucinations	0.001	0.999	0.000
S41.0 Open wound of shoulder	0.001	0.999	0.000
S42.2 Fracture of upper end of humerus	0.001	0.999	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.001	0.999	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.000	0.999	0.001
S41 Open wound of shoulder and upper arm	0.001	0.999	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.001	0.999	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.001	0.999	0.000
Z39.0 Care and examination immediately after delivery	0.001	0.999	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.000	0.999	0.001
M24.21 Disorder of ligament (Shoulder region)	0.001	0.999	0.000
S32.20 Fracture of coccyx (closed)	0.000	0.999	0.001
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.000	0.999	0.001
C21.1 Anal canal	0.001	0.999	0.000
C84.4 Peripheral T-cell lymphoma	0.000	0.999	0.001
G24.8 Other dystonia	0.001	0.999	0.000
K51.8 Other ulcerative colitis	0.001	0.999	0.000
Z39.2 Routine postpartum follow-up	0.001	0.999	0.000
E65 Localised adiposity	0.001	0.999	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.001	0.999	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.000	0.999	0.001
S91.3 Open wound of other parts of foot	0.001	0.999	0.000
A86 Unspecified viral encephalitis	0.000	0.999	0.001
M82 Osteoporosis in diseases classified elsewhere	0.001	0.999	0.000
S32.41 Fracture of acetabulum (open)	0.000	0.999	0.001
A40.3 Septicaemia due to Streptococcus pneumoniae	0.001	0.999	0.000
I25.5 Ischaemic cardiomyopathy	0.000	0.999	0.001
N05.2 Diffuse membranous glomerulonephritis	0.000	0.999	0.001
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.000	0.999	0.001
T93.9 Sequelae of unspecified injury of lower limb	0.000	0.999	0.001
S96 Injury of muscle and tendon at ankle and foot level	0.001	0.999	0.000
D23.5 Skin of trunk	0.001	0.999	0.000
E23.2 Diabetes insipidus	0.000	0.999	0.001
K01.0 Embedded teeth	0.001	0.999	0.000
S42.3 Fracture of shaft of humerus	0.001	0.999	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.001	0.999	0.000
M83 Adult osteomalacia	0.001	0.999	0.000
S48 Traumatic amputation of shoulder and upper arm	0.001	0.999	0.000
S44 Injury of nerves at shoulder and upper arm level	0.001	0.999	0.000
S47 Crushing injury of shoulder and upper arm	0.001	0.999	0.000
S42.21 Fracture of upper end of humerus (open)	0.001	0.999	0.000
S92.41 Fracture of great toe (open)	0.001	0.999	0.000
G24.4 Idiopathic orofacial dystonia	0.001	0.999	0.000
G24.2 Idiopathic nonfamilial dystonia	0.001	0.999	0.000
G24.0 Drug-induced dystonia	0.001	0.999	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.001	0.999	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.999	0.001
S96.8 Injury of other muscles and tendons at ankle and foot level	0.001	0.999	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.001	0.999	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.001	0.999	0.000
F50.0 Anorexia nervosa	0.001	0.999	0.000
M82.1 Osteoporosis in endocrine disorders	0.001	0.999	0.000
O14.9 Preeclampsia, unspecified	0.001	0.999	0.000
S45.9 Injury of unspecified blood vessel at shoulder and upper arm level	0.001	0.999	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.001	0.999	0.000
S91.0 Open wound of ankle	0.001	0.999	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.000	0.999	0.001
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.001	0.999	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.001	0.999	0.000
S41.1 Open wound of upper arm	0.001	0.999	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.001	0.999	0.000
M24.23 Disorder of ligament (Forearm)	0.001	0.999	0.000
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.001	0.999	0.000
A40.2 Septicaemia due to streptococcus, group D	0.001	0.999	0.000
D35.9 Endocrine gland, unspecified	0.000	0.999	0.001
D35.8 Pluriglandular involvement	0.000	0.999	0.001
D35.7 Other specified endocrine glands	0.000	0.999	0.001
D35.6 Aortic body and other paraganglia	0.000	0.999	0.001
D35.5 Carotid body	0.000	0.999	0.001
D35.4 Pineal gland	0.000	0.999	0.001
D35.3 Craniopharyngeal duct	0.000	0.999	0.001
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.999	0.001
S41.7 Multiple open wounds of shoulder and upper arm	0.001	0.999	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.001	0.999	0.000
S46.3 Injury of muscle and tendon of triceps	0.001	0.999	0.000
S91.1 Open wound of toe(s) without damage to nail	0.001	0.999	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.001	0.999	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.001	0.999	0.000
D41.9 Urinary organ, unspecified	0.000	0.999	0.001
D41.7 Other urinary organs	0.000	0.999	0.001
D41.3 Urethra	0.000	0.999	0.001
M83.8 Other adult osteomalacia	0.001	0.999	0.000
S45.8 Injury of other blood vessels at shoulder and upper arm level	0.001	0.999	0.000
S45.7 Injury of multiple blood vessels at shoulder and upper arm level	0.001	0.999	0.000
S45.3 Injury of superficial vein at shoulder and upper arm level	0.001	0.999	0.000
S45.2 Injury of axillary or brachial vein	0.001	0.999	0.000
S45.1 Injury of brachial artery	0.001	0.999	0.000
S45.0 Injury of axillary artery	0.001	0.999	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.000	0.999	0.001
G24.1 Idiopathic familial dystonia	0.001	0.999	0.000
K62.8 Other specified diseases of anus and rectum	0.001	0.999	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.001	0.999	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.001	0.999	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.001	0.999	0.000
S92.4 Fracture of great toe	0.001	0.999	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.001	0.999	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.999	0.001
I49.1 Atrial premature depolarisation	0.001	0.999	0.000
M83.9 Adult osteomalacia, unspecified	0.001	0.999	0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.001	0.999	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.001	0.999	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.001	0.999	0.000
M83.80 Other adult osteomalacia (Multiple sites)	0.001	0.999	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.001	0.999	0.000
M83.5 Other drug-induced osteomalacia in adults	0.001	0.999	0.000
M83.4 Aluminum bone disease	0.001	0.999	0.000
M83.2 Adult osteomalacia due to malabsorption	0.001	0.999	0.000
M83.0 Puerperal osteomalacia	0.001	0.999	0.000
S13.1 Dislocation of cervical vertebra	0.001	0.999	0.000
S42.1 Fracture of scapula	0.001	0.999	0.000
S44.9 Injury of unspecified nerve at shoulder and upper arm level	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations