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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0062
log Bayes Factor = 68.7461
contains 4 variants:
rs72678805
lBF = 14.053
Chr 1 : 59,180,079
rs12201940
lBF = 14.344
Chr 6 : 5,859,679
rs78867611
lBF = 12.752
Chr11 : 27,453,743
rs61952371
lBF = 11.118
Chr13 : 20,588,537
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K80 Cholelithiasis
1.000 0.000 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
R50-R69 General symptoms and signs
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
S00-S09 Injuries to the head
1.000 0.000 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
A30-A49 Other bacterial diseases
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
R63 Symptoms and signs concerning food and fluid intake
1.000 0.000 0.000
R52 Pain, not elsewhere classified
1.000 0.000 0.000
D10-D36 Benign neoplasms
1.000 0.000 0.000
C64-C68 Malignant neoplasms of urinary tract
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
S60-S69 Injuries to the wrist and hand
0.999 0.001 0.000
A41 Other septicaemia
0.999 0.001 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.999 0.001 0.000
M70-M79 Other soft tissue disorders
0.998 0.002 0.000
M80-M85 Disorders of bone density and structure
0.998 0.002 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.998 0.002 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.997 0.003 0.000
S06 Intracranial injury
0.997 0.003 0.000
R59 Enlarged lymph nodes
0.996 0.004 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.996 0.004 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.996 0.004 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.995 0.005 0.000
K70-K77 Diseases of liver
0.995 0.005 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.995 0.005 0.000
R52.1 Chronic intractable pain
0.994 0.006 0.000
K85 Acute pancreatitis
0.993 0.007 0.000
M20-M25 Other joint disorders
0.993 0.007 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.992 0.008 0.000
D12.3 Transverse colon
0.992 0.008 0.000
M84 Disorders of continuity of bone
0.991 0.009 0.000
Chapter VI Diseases of the nervous system
0.991 0.009 0.000
R50 Fever of unknown origin
0.990 0.010 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.990 0.010 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.990 0.010 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.990 0.010 0.000
C50-C50 Malignant neoplasm of breast
0.989 0.011 0.000
M79.8 Other specified soft tissue disorders
0.989 0.011 0.000
D68 Other coagulation defects
0.987 0.013 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.986 0.014 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.986 0.014 0.000
A41.8 Other specified septicaemia
0.986 0.014 0.000
M24 Other specific joint derangements
0.984 0.016 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.983 0.017 0.000
S90-S99 Injuries to the ankle and foot
0.982 0.018 0.000
R50.9 Fever, unspecified
0.982 0.018 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.982 0.018 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.982 0.018 0.000
C50 Malignant neoplasm of breast
0.982 0.018 0.000
R63.0 Anorexia
0.982 0.018 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.980 0.020 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.980 0.020 0.000
F30-F39 Mood [affective] disorders
0.980 0.020 0.000
M86-M90 Other osteopathies
0.979 0.021 0.000
E00-E07 Disorders of thyroid gland
0.979 0.021 0.000
S01 Open wound of head
0.979 0.021 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.979 0.021 0.000
K85.1 Biliary acute pancreatitis
0.977 0.023 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.977 0.023 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.973 0.027 0.000
M05 Seropositive rheumatoid arthritis
0.973 0.027 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.972 0.028 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.972 0.028 0.000
F31 Bipolar affective disorder
0.971 0.029 0.000
S00 Superficial injury of head
0.968 0.032 0.000
B35-B49 Mycoses
0.965 0.035 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.964 0.036 0.000
D34 Benign neoplasm of thyroid gland
0.963 0.037 0.000
A49 Bacterial infection of unspecified site
0.962 0.038 0.000
D12.6 Colon, unspecified
0.960 0.040 0.000
K50-K52 Noninfective enteritis and colitis
0.959 0.041 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.955 0.045 0.000
M10 Gout
0.955 0.045 0.000
K75 Other inflammatory liver diseases
0.955 0.045 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.954 0.046 0.000
M23 Internal derangement of knee
0.953 0.047 0.000
S06.5 Traumatic subdural haemorrhage
0.953 0.047 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.953 0.047 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.953 0.047 0.000
D23 Other benign neoplasms of skin
0.952 0.048 0.000
R59.9 Enlarged lymph nodes, unspecified
0.951 0.049 0.000
C50.9 Breast, unspecified
0.947 0.053 0.000
D00-D09 In situ neoplasms
0.947 0.053 0.000
M23.3 Other meniscus derangements
0.947 0.053 0.000
R41.3 Other amnesia
0.946 0.054 0.000
C67 Malignant neoplasm of bladder
0.945 0.055 0.000
C50.2 Upper-inner quadrant of breast
0.945 0.055 0.000
R63.4 Abnormal weight loss
0.944 0.056 0.000
C51-C58 Malignant neoplasms of female genital organs
0.944 0.056 0.000
R52.9 Pain, unspecified
0.943 0.057 0.000
E04 Other non-toxic goitre
0.942 0.058 0.000
S64 Injury of nerves at wrist and hand level
0.941 0.059 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.941 0.059 0.000
K50 Crohn's disease [regional enteritis]
0.941 0.059 0.000
R59.0 Localised enlarged lymph nodes
0.940 0.060 0.000
S01.3 Open wound of ear
0.939 0.061 0.000
S00.8 Superficial injury of other parts of head
0.938 0.062 0.000
D12.0 Caecum
0.936 0.064 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.935 0.065 0.000
Q21 Congenital malformations of cardiac septa
0.935 0.065 0.000
S32 Fracture of lumbar spine and pelvis
0.933 0.067 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.933 0.067 0.000
E04.9 Non-toxic goitre, unspecified
0.932 0.068 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.930 0.070 0.000
K82 Other diseases of gallbladder
0.930 0.070 0.000
K81 Cholecystitis
0.930 0.070 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.929 0.071 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.928 0.072 0.000
E20-E35 Disorders of other endocrine glands
0.928 0.072 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.928 0.072 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.927 0.073 0.000
D68.9 Coagulation defect, unspecified
0.926 0.074 0.000
S69 Other and unspecified injuries of wrist and hand
0.926 0.074 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.926 0.074 0.000
M10.9 Gout, unspecified
0.923 0.077 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.923 0.077 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.922 0.078 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.922 0.078 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.922 0.078 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.922 0.078 0.000
E06 Thyroiditis
0.920 0.080 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.920 0.080 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.920 0.080 0.000
G70-G73 Diseases of myoneural junction and muscle
0.920 0.080 0.000
M85 Other disorders of bone density and structure
0.919 0.081 0.000
K12 Stomatitis and related lesions
0.919 0.081 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.918 0.082 0.000
K50.0 Crohn's disease of small intestine
0.918 0.082 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.917 0.083 0.000
R59.1 Generalised enlarged lymph nodes
0.917 0.083 0.000
R52.2 Other chronic pain
0.917 0.083 0.000
M21 Other acquired deformities of limbs
0.916 0.084 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.915 0.085 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.914 0.086 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.914 0.086 0.000
M84.4 Pathological fracture, not elsewhere classified
0.914 0.086 0.000
M79.5 Residual foreign body in soft tissue
0.913 0.087 0.000
F10.1 Harmful use
0.912 0.088 0.000
K70 Alcoholic liver disease
0.912 0.088 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.908 0.092 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.908 0.092 0.000
R63.5 Abnormal weight gain
0.907 0.093 0.000
S01.2 Open wound of nose
0.906 0.094 0.000
M89 Other disorders of bone
0.906 0.094 0.000
K80.4 Calculus of bile duct with cholecystitis
0.905 0.095 0.000
E50-E64 Other nutritional deficiencies
0.904 0.096 0.000
T93 Sequelae of injuries of lower limb
0.903 0.097 0.000
K80.8 Other cholelithiasis
0.903 0.097 0.000
F60-F69 Disorders of adult personality and behaviour
0.903 0.097 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.901 0.099 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.900 0.100 0.000
M45-M49 Spondylopathies
0.900 0.100 0.000
D16 Benign neoplasm of bone and articular cartilage
0.900 0.100 0.000
S60 Superficial injury of wrist and hand
0.898 0.102 0.000
K05 Gingivitis and periodontal diseases
0.896 0.104 0.000
S64.4 Injury of digital nerve of other finger
0.895 0.105 0.000
M24.0 Loose body in joint
0.895 0.105 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.894 0.106 0.000
D23.6 Skin of upper limb, including shoulder
0.893 0.107 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.893 0.107 0.000
S92 Fracture of foot, except ankle
0.893 0.107 0.000
R82 Other abnormal findings in urine
0.891 0.109 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.890 0.110 0.000
S91 Open wound of ankle and foot
0.890 0.110 0.000
G30-G32 Other degenerative diseases of the nervous system
0.890 0.110 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.889 0.111 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.889 0.111 0.000
Chapter VII Diseases of the eye and adnexa
0.889 0.111 0.000
S05 Injury of eye and orbit
0.889 0.111 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.887 0.113 0.000
C01 Malignant neoplasm of base of tongue
0.886 0.113 0.000
D03 Melanoma in situ
0.885 0.115 0.000
K65-K67 Diseases of peritoneum
0.885 0.115 0.000
K14 Diseases of tongue
0.884 0.116 0.000
Chapter XXII Codes for special purposes
0.882 0.118 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.882 0.118 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.879 0.120 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.879 0.121 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.879 0.121 0.000
B15-B19 Viral hepatitis
0.877 0.123 0.000
E07 Other disorders of thyroid
0.877 0.123 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.874 0.126 0.000
X60-X84 Intentional self-harm
0.874 0.126 0.000
A40 Streptococcal septicaemia
0.874 0.126 0.000
K12.1 Other forms of stomatitis
0.873 0.127 0.000
S32.4 Fracture of acetabulum
0.873 0.127 0.000
K81.0 Acute cholecystitis
0.873 0.127 0.000
S69.9 Unspecified injury of wrist and hand
0.873 0.127 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.872 0.128 0.000
M77 Other enthesopathies
0.871 0.129 0.000
B44 Aspergillosis
0.871 0.129 0.000
Q21.0 Ventricular septal defect
0.870 0.130 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.870 0.130 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.870 0.130 0.000
M24.5 Contracture of joint
0.869 0.131 0.000
D60-D64 Aplastic and other anaemias
0.869 0.131 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.868 0.132 0.000
F20 Schizophrenia
0.868 0.132 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.867 0.133 0.000
E06.3 Autoimmune thyroiditis
0.866 0.134 0.000
C56 Malignant neoplasm of ovary
0.866 0.134 0.000
G83 Other paralytic syndromes
0.865 0.135 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.864 0.136 0.000
M10.99 Gout, unspecified (Site unspecified)
0.864 0.136 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.863 0.137 0.000
R53 Malaise and fatigue
0.863 0.137 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.862 0.138 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.861 0.138 0.000
K81.9 Cholecystitis, unspecified
0.861 0.139 0.000
R46 Symptoms and signs involving appearance and behaviour
0.861 0.139 0.000
K50.9 Crohn's disease, unspecified
0.860 0.140 0.000
S06.3 Focal brain injury
0.860 0.140 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.859 0.141 0.000
M84.48 Pathological fracture, not elsewhere classified (Other)
0.858 0.142 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.858 0.142 0.000
K82.8 Other specified diseases of gallbladder
0.857 0.143 0.000
S06.8 Other intracranial injuries
0.857 0.143 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.857 0.143 0.000
T88.4 Failed or difficult intubation
0.856 0.144 0.000
D68.6 Other Thrombophilia
0.855 0.145 0.000
M84.0 Malunion of fracture
0.855 0.145 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.855 0.145 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.855 0.145 0.000
K73 Chronic hepatitis, not elsewhere classified
0.855 0.145 0.000
C67.3 Anterior wall of bladder
0.854 0.146 0.000
M79.54 Residual foreign body in soft tissue (Hand)
0.854 0.146 0.000
B49 Unspecified mycosis
0.854 0.146 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.853 0.147 0.000
M90 Osteopathies in diseases classified elsewhere
0.853 0.147 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.851 0.149 0.000
M06.0 Seronegative rheumatoid arthritis
0.851 0.149 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.850 0.150 0.000
K85.2 Alcohol-induced acute pancreatitis
0.848 0.152 0.000
S62 Fracture at wrist and hand level
0.848 0.152 0.000
G71 Primary disorders of muscles
0.847 0.153 0.000
D66 Hereditary factor VIII deficiency
0.847 0.153 0.000
D75 Other diseases of blood and blood-forming organs
0.845 0.155 0.000
D73 Diseases of spleen
0.843 0.157 0.000
F10.2 Dependence syndrome
0.842 0.158 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.842 0.158 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.841 0.159 0.000
T91 Sequelae of injuries of neck and trunk
0.841 0.159 0.000
M24.1 Other articular cartilage disorders
0.840 0.160 0.000
W20-W49 Exposure to inanimate mechanical forces
0.840 0.160 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.840 0.160 0.000
K75.8 Other specified inflammatory liver diseases
0.839 0.161 0.000
M21.1 Varus deformity, not elsewhere classified
0.839 0.161 0.000
M47 Spondylosis
0.838 0.162 0.000
K11 Diseases of salivary glands
0.837 0.163 0.000
X50-X57 Overexertion, travel and privation
0.837 0.163 0.000
F31.9 Bipolar affective disorder, unspecified
0.837 0.163 0.000
C50.5 Lower-outer quadrant of breast
0.837 0.163 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.835 0.165 0.000
C50.1 Central portion of breast
0.835 0.165 0.000
D68.0 Von Willebrand's disease
0.835 0.165 0.000
G83.4 Cauda equina syndrome
0.834 0.166 0.000
D30 Benign neoplasm of urinary organs
0.834 0.166 0.000
D12.2 Ascending colon
0.834 0.166 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.834 0.166 0.000
F60 Specific personality disorders
0.834 0.166 0.000
S00.3 Superficial injury of nose
0.834 0.166 0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.833 0.167 0.000
K75.4 Autoimmune hepatitis
0.833 0.167 0.000
K09 Cysts of oral region, not elsewhere classified
0.833 0.167 0.000
T92 Sequelae of injuries of upper limb
0.833 0.167 0.000
K70.0 Alcoholic fatty liver
0.832 0.168 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.831 0.169 0.000
S32.40 Fracture of acetabulum (closed)
0.830 0.170 0.000
K76 Other diseases of liver
0.830 0.170 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.830 0.170 0.000
S92.3 Fracture of metatarsal bone
0.828 0.172 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.827 0.173 0.000
R82.8 Abnormal findings on cytological and histological examination of urine
0.827 0.173 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.827 0.173 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.826 0.174 0.000
S40-S49 Injuries to the shoulder and upper arm
0.826 0.174 0.000
T86 Failure and rejection of transplanted organs and tissues
0.826 0.174 0.000
D26 Other benign neoplasms of uterus
0.825 0.175 0.000
K14.9 Disease of tongue, unspecified
0.825 0.175 0.000
Q21.1 Atrial septal defect
0.824 0.176 0.000
E20 Hypoparathyroidism
0.824 0.176 0.000
M79.88 Other specified soft tissue disorders (Other)
0.822 0.178 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.822 0.178 0.000
F11 Mental and behavioural disorders due to use of opioids
0.822 0.178 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.821 0.179 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.821 0.179 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.820 0.180 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.820 0.180 0.000
T66-T78 Other and unspecified effects of external causes
0.820 0.180 0.000
C49.2 Connective and soft tissue of lower limb, including hip
0.820 0.180 0.000
A49.1 Streptococcal infection, unspecified
0.820 0.180 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.819 0.181 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.818 0.182 0.000
K66 Other disorders of peritoneum
0.818 0.182 0.000
Q80-Q89 Other congenital malformations
0.817 0.183 0.000
D23.7 Skin of lower limb, including hip
0.817 0.183 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.817 0.183 0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge
0.817 0.183 0.000
D68.5 Primary Thrombophilia
0.816 0.184 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.816 0.184 0.000
T98 Sequelae of other and unspecified effects of external causes
0.816 0.184 0.000
S91.1 Open wound of toe(s) without damage to nail
0.816 0.184 0.000
M91-M94 Chondropathies
0.815 0.185 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.815 0.185 0.000
K85.9 Acute pancreatitis, unspecified
0.815 0.185 0.000
A49.8 Other bacterial infections of unspecified site
0.815 0.185 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.814 0.186 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.813 0.187 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.813 0.187 0.000
R50.0 Fever with chills
0.812 0.188 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.812 0.188 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.811 0.189 0.000
X00-X09 Exposure to smoke, fire and flames
0.810 0.189 0.000
T46.1 Calcium-channel blockers
0.810 0.190 0.000
D62 Acute posthaemorrhagic anaemia
0.810 0.190 0.000
W50-W64 Exposure to animate mechanical forces
0.809 0.191 0.000
D03.7 Melanoma in situ of lower limb, including hip
0.809 0.191 0.000
E27 Other disorders of adrenal gland
0.808 0.192 0.000
M85.8 Other specified disorders of bone density and structure
0.808 0.192 0.000
G61 Inflammatory polyneuropathy
0.808 0.192 0.000
E55 Vitamin D deficiency
0.807 0.193 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.807 0.193 0.000
D12.9 Anus and anal canal
0.806 0.194 0.000
K76.9 Liver disease, unspecified
0.806 0.194 0.000
C67.4 Posterior wall of bladder
0.806 0.194 0.000
A49.0 Staphylococcal infection, unspecified
0.805 0.195 0.000
F20.9 Schizophrenia, unspecified
0.805 0.195 0.000
M06.4 Inflammatory polyarthropathy
0.805 0.195 0.000
M24.2 Disorder of ligament
0.805 0.195 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.805 0.195 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.804 0.196 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.804 0.196 0.000
R43 Disturbances of smell and taste
0.803 0.196 0.000
E07.9 Disorder of thyroid, unspecified
0.803 0.197 0.000
B37 Candidiasis
0.803 0.197 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.801 0.199 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.801 0.199 0.000
D21.0 Connective and other soft tissue of head, face and neck
0.801 0.199 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.799 0.201 0.000
D55-D59 Haemolytic anaemias
0.798 0.202 0.000
S10-S19 Injuries to the neck
0.798 0.202 0.000
B95-B98 Bacterial, viral and other infectious agents
0.797 0.203 0.000
W00-W19 Falls
0.796 0.204 0.000
T79-T79 Certain early complications of trauma
0.795 0.205 0.000
M77.1 Lateral epicondylitis
0.795 0.205 0.000
A49.9 Bacterial infection, unspecified
0.795 0.205 0.000
M87 Osteonecrosis
0.794 0.205 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.794 0.206 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.793 0.206 0.000
C07 Malignant neoplasm of parotid gland
0.793 0.207 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.793 0.207 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.791 0.209 0.000
C09 Malignant neoplasm of tonsil
0.790 0.210 0.000
K82.4 Cholesterolosis of gallbladder
0.790 0.210 0.000
V40-V49 Car occupant injured in transport accident
0.790 0.210 0.000
M89.9 Disorder of bone, unspecified
0.789 0.211 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.789 0.211 0.000
V80-V89 Other land transport accidents
0.788 0.212 0.000
M79.2 Neuralgia and neuritis, unspecified
0.788 0.212 0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.788 0.212 0.000
M23.5 Chronic instability of knee
0.788 0.212 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.787 0.213 0.000
Q50-Q56 Congenital malformations of genital organs
0.787 0.213 0.000
Chapter VIII Diseases of the ear and mastoid process
0.787 0.213 0.000
M10.96 Gout, unspecified (Lower leg)
0.787 0.213 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.786 0.214 0.000
M24.54 Contracture of joint (Hand)
0.786 0.214 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.785 0.215 0.000
S65 Injury of blood vessels at wrist and hand level
0.784 0.216 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.784 0.216 0.000
M60-M63 Disorders of muscles
0.784 0.216 0.000
M00-M03 Infectious arthropathies
0.784 0.216 0.000
K70.1 Alcoholic hepatitis
0.784 0.216 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.783 0.216 0.000
M47.9 Spondylosis, unspecified
0.783 0.217 0.000
K05.3 Chronic periodontitis
0.783 0.217 0.000
T87 Complications peculiar to reattachment and amputation
0.783 0.217 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.782 0.218 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.781 0.219 0.000
S92.30 Fracture of metatarsal bone (closed)
0.781 0.219 0.000
G30 Alzheimer's disease
0.781 0.219 0.000
B65-B83 Helminthiases
0.781 0.219 0.000
C67.8 Overlapping lesion of bladder
0.780 0.220 0.000
M71 Other bursopathies
0.780 0.220 0.000
D25 Leiomyoma of uterus
0.780 0.220 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.779 0.221 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.779 0.221 0.000
R26 Abnormalities of gait and mobility
0.779 0.221 0.000
D04 Carcinoma in situ of skin
0.779 0.221 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.778 0.221 0.000
C65 Malignant neoplasm of renal pelvis
0.778 0.221 0.000
M88 Paget's disease of bone [osteitis deformans]
0.778 0.222 0.000
Q00-Q07 Congenital malformations of the nervous system
0.778 0.222 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.777 0.223 0.000
C67.1 Dome of bladder
0.777 0.223 0.000
M10.94 Gout, unspecified (Hand)
0.777 0.223 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.777 0.223 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.776 0.224 0.000
M34 Systemic sclerosis
0.776 0.224 0.000
K75.9 Inflammatory liver disease, unspecified
0.776 0.224 0.000
Y52 Agents primarily affecting the cardiovascular system
0.776 0.224 0.000
R46.8 Other symptoms and signs involving appearance and behaviour
0.776 0.224 0.000
D23.2 Skin of ear and external auricular canal
0.775 0.225 0.000
S02 Fracture of skull and facial bones
0.773 0.227 0.000
Y00-Y09 Assault
0.773 0.227 0.000
B18 Chronic viral hepatitis
0.773 0.227 0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)
0.773 0.227 0.000
S06.2 Diffuse brain injury
0.772 0.228 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.772 0.228 0.000
M70.2 Olecranon bursitis
0.771 0.229 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.771 0.229 0.000
M24.07 Loose body in joint (Ankle and foot)
0.770 0.230 0.000
F34 Persistent mood [affective] disorders
0.770 0.230 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.769 0.231 0.000
H53-H54 Visual disturbances and blindness
0.769 0.231 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.768 0.232 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.768 0.232 0.000
C51 Malignant neoplasm of vulva
0.767 0.233 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.767 0.233 0.000
D28.2 Uterine tubes and ligaments
0.767 0.233 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.766 0.234 0.000
M82 Osteoporosis in diseases classified elsewhere
0.766 0.234 0.000
M24.02 Loose body in joint (Upper arm)
0.766 0.234 0.000
A46 Erysipelas
0.765 0.235 0.000
S06.4 Epidural haemorrhage
0.765 0.235 0.000
T88.5 Other complications of anaesthesia
0.764 0.236 0.000
D32 Benign neoplasm of meninges
0.764 0.236 0.000
S01.7 Multiple open wounds of head
0.763 0.237 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.763 0.237 0.000
K83 Other diseases of biliary tract
0.763 0.237 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.763 0.237 0.000
M90.7 Fracture of bone in neoplastic disease
0.763 0.237 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.762 0.237 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.762 0.238 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.762 0.238 0.000
K70.4 Alcoholic hepatic failure
0.762 0.238 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.761 0.239 0.000
D68.8 Other specified coagulation defects
0.761 0.239 0.000
D16.4 Bones of skull and face
0.761 0.239 0.000
M06.3 Rheumatoid nodule
0.761 0.239 0.000
M85.0 Fibrous dysplasia (monostotic)
0.761 0.239 0.000
R82.9 Other and unspecified abnormal finding in urine
0.760 0.240 0.000
M31 Other necrotising vasculopathies
0.760 0.240 0.000
X20-X29 Contact with venomous animals and plants
0.760 0.240 0.000
S99 Other and unspecified injuries of ankle and foot
0.760 0.240 0.000
G61.0 Guillain-Barre syndrome
0.759 0.241 0.000
M14 Arthropathies in other diseases classified elsewhere
0.759 0.241 0.000
C67.6 Ureteric orifice
0.759 0.241 0.000
S05.1 Contusion of eyeball and orbital tissues
0.759 0.241 0.000
K12.0 Recurrent oral aphthae
0.759 0.241 0.000
K01 Embedded and impacted teeth
0.759 0.241 0.000
K11.8 Other diseases of salivary glands
0.759 0.241 0.000
M79.1 Myalgia
0.758 0.242 0.000
C67.5 Bladder neck
0.758 0.242 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.757 0.242 0.000
S06.80 Other intracranial injuries (without open intracranial wound)
0.757 0.243 0.000
X10-X19 Contact with heat and hot substances
0.757 0.243 0.000
Q27 Other congenital malformations of peripheral vascular system
0.756 0.243 0.000
F10.9 Unspecified mental and behavioural disorder
0.756 0.244 0.000
M81 Osteoporosis without pathological fracture
0.756 0.244 0.000
C66 Malignant neoplasm of ureter
0.756 0.244 0.000
Q23 Congenital malformations of aortic and mitral valves
0.756 0.244 0.000
G82 Paraplegia and tetraplegia
0.756 0.244 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.755 0.245 0.000
R63.1 Polydipsia
0.755 0.245 0.000
D73.0 Hyposplenism
0.755 0.245 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.755 0.245 0.000
T93.1 Sequelae of fracture of femur
0.754 0.246 0.000
K73.9 Chronic hepatitis, unspecified
0.754 0.246 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.754 0.246 0.000
S60.0 Contusion of finger(s) without damage to nail
0.753 0.247 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.753 0.247 0.000
G71.1 Myotonic disorders
0.752 0.248 0.000
K07 Dentofacial anomalies [including malocclusion]
0.752 0.248 0.000
K00 Disorders of tooth development and eruption
0.751 0.249 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.751 0.249 0.000
S01.0 Open wound of scalp
0.751 0.249 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.750 0.250 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.750 0.250 0.000
G03 Meningitis due to other and unspecified causes
0.750 0.250 0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis
0.750 0.250 0.000
Q24 Other congenital malformations of heart
0.750 0.250 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.750 0.250 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.749 0.250 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.749 0.251 0.000
R58 Haemorrhage, not elsewhere classified
0.749 0.251 0.000
E20.9 Hypoparathyroidism, unspecified
0.749 0.251 0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder
0.749 0.251 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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