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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

Affx-21645068
log Bayes Factor = 13.8948
Chromosome 3   position 17,152,151  (GRCh37) Explore Affx-21645068 on Ensembl!
Variant Affx-21645068 is part of Cluster X0249

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.998 0.002 0.000
I50 Heart failure
0.997 0.003 0.000
I50.0 Congestive heart failure
0.995 0.005 0.000
I73 Other peripheral vascular diseases
0.993 0.007 0.000
I51 Complications and ill-defined descriptions of heart disease
0.992 0.008 0.000
Chapter XXI Factors influencing health status and contact with health services
0.988 0.012 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.983 0.017 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.981 0.019 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.977 0.023 0.000
Chapter XX External causes of morbidity and mortality
0.974 0.026 0.000
D50-D53 Nutritional anaemias
0.974 0.026 0.000
E70-E90 Metabolic disorders
0.972 0.028 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.970 0.030 0.000
D50 Iron deficiency anaemia
0.966 0.034 0.000
I51.7 Cardiomegaly
0.966 0.034 0.000
I73.0 Raynaud's syndrome
0.964 0.036 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.963 0.037 0.000
M20-M25 Other joint disorders
0.962 0.038 0.000
E83 Disorders of mineral metabolism
0.962 0.038 0.000
I42 Cardiomyopathy
0.961 0.039 0.000
I73.9 Peripheral vascular disease, unspecified
0.958 0.042 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.953 0.047 0.000
Z50 Care involving use of rehabilitation procedures
0.946 0.054 0.000
Z72 Problems related to lifestyle
0.945 0.055 0.000
D50.9 Iron deficiency anaemia, unspecified
0.944 0.056 0.000
Chapter VI Diseases of the nervous system
0.940 0.060 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.940 0.060 0.000
M25 Other joint disorders, not elsewhere classified
0.936 0.064 0.000
J20-J22 Other acute lower respiratory infections
0.935 0.065 0.000
I51.8 Other ill-defined heart diseases
0.933 0.067 0.000
Chapter I Certain infectious and parasitic diseases
0.932 0.068 0.000
Z72.0 Tobacco use
0.921 0.079 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.920 0.080 0.000
D50.8 Other iron deficiency anaemias
0.917 0.083 0.000
Y43 Primarily systemic agents
0.913 0.086 0.000
E20-E35 Disorders of other endocrine glands
0.906 0.094 0.000
Z50.1 Other physical therapy
0.906 0.094 0.000
E83.1 Disorders of iron metabolism
0.905 0.095 0.000
S50-S59 Injuries to the elbow and forearm
0.905 0.095 0.000
T66-T78 Other and unspecified effects of external causes
0.903 0.097 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.902 0.098 0.000
J60-J70 Lung diseases due to external agents
0.894 0.106 0.000
S70-S79 Injuries to the hip and thigh
0.891 0.109 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.891 0.109 0.000
E83.5 Disorders of calcium metabolism
0.891 0.109 0.000
J22 Unspecified acute lower respiratory infection
0.889 0.111 0.000
I42.0 Dilated cardiomyopathy
0.889 0.111 0.000
Z47 Other orthopaedic follow-up care
0.888 0.112 0.000
Y43.3 Other antineoplastic drugs
0.885 0.115 0.000
S60-S69 Injuries to the wrist and hand
0.881 0.119 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.877 0.123 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.873 0.127 0.000
I77 Other disorders of arteries and arterioles
0.873 0.127 0.000
Z51 Other medical care
0.870 0.130 0.000
M25.5 Pain in joint
0.867 0.133 0.000
I44 Atrioventricular and left bundle-branch block
0.867 0.133 0.000
M50-M54 Other dorsopathies
0.867 0.133 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.867 0.133 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.865 0.135 0.000
J90-J94 Other diseases of pleura
0.860 0.140 0.000
M25.7 Osteophyte
0.860 0.140 0.000
I46 Cardiac arrest
0.851 0.149 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.847 0.153 0.000
E87.6 Hypokalaemia
0.844 0.156 0.000
Y52 Agents primarily affecting the cardiovascular system
0.840 0.160 0.000
I47 Paroxysmal tachycardia
0.840 0.160 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.839 0.161 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.834 0.166 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.834 0.166 0.000
E83.4 Disorders of magnesium metabolism
0.833 0.167 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.832 0.168 0.000
J40-J47 Chronic lower respiratory diseases
0.832 0.168 0.000
J09-J18 Influenza and pneumonia
0.829 0.171 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.824 0.176 0.000
S52 Fracture of forearm
0.820 0.180 0.000
B95-B98 Bacterial, viral and other infectious agents
0.819 0.181 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.819 0.181 0.000
I72 Other aneurysm
0.818 0.182 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.817 0.183 0.000
J69 Pneumonitis due to solids and liquids
0.816 0.184 0.000
I42.9 Cardiomyopathy, unspecified
0.812 0.188 0.000
A30-A49 Other bacterial diseases
0.811 0.189 0.000
J84 Other interstitial pulmonary diseases
0.811 0.189 0.000
I33 Acute and subacute endocarditis
0.808 0.192 0.000
I60-I69 Cerebrovascular diseases
0.808 0.192 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.806 0.194 0.000
W20-W49 Exposure to inanimate mechanical forces
0.805 0.195 0.000
Z72.1 Alcohol use
0.805 0.195 0.000
V10-V19 Pedal cyclist injured in transport accident
0.804 0.196 0.000
S72 Fracture of femur
0.802 0.198 0.000
I44.7 Left bundle-branch block, unspecified
0.801 0.199 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.801 0.199 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.800 0.200 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.799 0.201 0.000
S20-S29 Injuries to the thorax
0.797 0.203 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.795 0.205 0.000
I50.9 Heart failure, unspecified
0.794 0.206 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.791 0.209 0.000
M25.56 Pain in joint (Lower leg)
0.789 0.211 0.000
S40-S49 Injuries to the shoulder and upper arm
0.787 0.213 0.000
M31 Other necrotising vasculopathies
0.785 0.215 0.000
T78 Adverse effects, not elsewhere classified
0.785 0.215 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.785 0.215 0.000
O80-O84 Delivery
0.782 0.218 0.000
D80-D89 Certain disorders involving the immune mechanism
0.781 0.219 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.780 0.219 0.000
I37 Pulmonary valve disorders
0.780 0.220 0.000
J45 Asthma
0.780 0.220 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.779 0.221 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.776 0.224 0.000
E21.0 Primary hyperparathyroidism
0.776 0.224 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.772 0.228 0.000
T00-T07 Injuries involving multiple body regions
0.770 0.230 0.000
M25.54 Pain in joint (Hand)
0.769 0.231 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.769 0.231 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.768 0.232 0.000
I74 Arterial embolism and thrombosis
0.767 0.232 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.767 0.233 0.000
T79-T79 Certain early complications of trauma
0.767 0.233 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.765 0.235 0.000
Z51.2 Other chemotherapy
0.763 0.237 0.000
M24 Other specific joint derangements
0.763 0.237 0.000
Chapter XXII Codes for special purposes
0.762 0.238 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.762 0.238 0.000
Z50.0 Cardiac rehabilitation
0.762 0.238 0.000
J69.0 Pneumonitis due to food and vomit
0.761 0.239 0.000
J00-J06 Acute upper respiratory infections
0.760 0.240 0.000
Z54 Convalescence
0.756 0.244 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.755 0.245 0.000
I47.2 Ventricular tachycardia
0.755 0.245 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.755 0.245 0.000
S52.0 Fracture of upper end of ulna
0.754 0.246 0.000
T68 Hypothermia
0.754 0.246 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.752 0.248 0.000
I78 Diseases of capillaries
0.751 0.249 0.000
Z50.5 Speech therapy
0.751 0.249 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.749 0.251 0.000
M25.77 Osteophyte (Ankle and foot)
0.749 0.251 0.000
I31 Other diseases of pericardium
0.748 0.252 0.000
J95-J99 Other diseases of the respiratory system
0.748 0.252 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.747 0.253 0.000
Z76 Persons encountering health services in other circumstances
0.746 0.254 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.746 0.254 0.000
Z29 Need for other prophylactic measures
0.744 0.255 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.744 0.256 0.000
Z43 Attention to artificial openings
0.743 0.257 0.000
G20-G26 Extrapyramidal and movement disorders
0.743 0.257 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.741 0.259 0.000
L91 Hypertrophic disorders of skin
0.738 0.262 0.000
S90-S99 Injuries to the ankle and foot
0.738 0.262 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.737 0.263 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.736 0.264 0.000
E89.0 Postprocedural hypothyroidism
0.736 0.264 0.000
Z49 Care involving dialysis
0.735 0.265 0.000
M34 Systemic sclerosis
0.735 0.265 0.000
J45.9 Asthma, unspecified
0.734 0.266 0.000
V20-V29 Motorcycle rider injured in transport accident
0.731 0.268 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.731 0.269 0.000
Z41 Procedures for purposes other than remedying health state
0.729 0.270 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.729 0.271 0.000
D51 Vitamin B12 deficiency anaemia
0.729 0.271 0.000
M23 Internal derangement of knee
0.729 0.271 0.000
Z22 Carrier of infectious disease
0.729 0.271 0.000
M05-M14 Inflammatory polyarthropathies
0.728 0.272 0.000
I46.0 Cardiac arrest with successful resuscitation
0.725 0.275 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.725 0.275 0.000
Z51.3 Blood transfusion without reported diagnosis
0.724 0.276 0.000
Z42 Follow-up care involving plastic surgery
0.724 0.276 0.000
J18 Pneumonia, organism unspecified
0.723 0.277 0.000
M54 Dorsalgia
0.722 0.278 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.721 0.279 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.720 0.279 0.000
O26.8 Other specified pregnancy-related conditions
0.720 0.280 0.000
Z47.8 Other specified orthopaedic follow-up care
0.720 0.280 0.000
J90 Pleural effusion, not elsewhere classified
0.719 0.281 0.000
I42.2 Other hypertrophic cardiomyopathy
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.716 0.284 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.716 0.284 0.000
S80-S89 Injuries to the knee and lower leg
0.714 0.286 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.714 0.286 0.000
S61 Open wound of wrist and hand
0.712 0.288 0.000
I73.8 Other specified peripheral vascular diseases
0.712 0.288 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.712 0.288 0.000
Chapter VIII Diseases of the ear and mastoid process
0.712 0.288 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.711 0.289 0.000
I51.6 Cardiovascular disease, unspecified
0.711 0.289 0.000
I51.5 Myocardial degeneration
0.711 0.289 0.000
I51.4 Myocarditis, unspecified
0.711 0.289 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.711 0.289 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.711 0.289 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.711 0.289 0.000
I51.0 Cardiac septal defect, acquired
0.711 0.289 0.000
L91.8 Other hypertrophic disorders of skin
0.710 0.290 0.000
Z51.5 Palliative care
0.709 0.291 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.708 0.292 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.708 0.292 0.000
S52.00 Fracture of upper end of ulna (closed)
0.707 0.293 0.000
E21.3 Hyperparathyroidism, unspecified
0.707 0.293 0.000
S62 Fracture at wrist and hand level
0.706 0.294 0.000
A80-A89 Viral infections of the central nervous system
0.705 0.295 0.000
D55-D59 Haemolytic anaemias
0.705 0.295 0.000
E40-E46 Malnutrition
0.703 0.297 0.000
E88 Other metabolic disorders
0.703 0.297 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.703 0.297 0.000
I69 Sequelae of cerebrovascular disease
0.702 0.298 0.000
Z57 Occupational exposure to risk-factors
0.702 0.298 0.000
M35 Other systemic involvement of connective tissue
0.701 0.299 0.000
Z74 Problems related to care-provider dependency
0.701 0.299 0.000
A41 Other septicaemia
0.701 0.299 0.000
M91-M94 Chondropathies
0.701 0.299 0.000
M60-M63 Disorders of muscles
0.701 0.299 0.000
M00-M03 Infectious arthropathies
0.701 0.299 0.000
M86-M90 Other osteopathies
0.700 0.300 0.000
M25.52 Pain in joint (Upper arm)
0.699 0.301 0.000
S51 Open wound of forearm
0.699 0.301 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.699 0.301 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.698 0.302 0.000
Y35-Y36 Legal intervention and operations of war
0.698 0.302 0.000
Y10-Y34 Event of undetermined intent
0.698 0.302 0.000
Y00-Y09 Assault
0.698 0.302 0.000
X85-X99 Assault
0.698 0.302 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.698 0.302 0.000
X50-X57 Overexertion, travel and privation
0.698 0.302 0.000
X30-X39 Exposure to forces of nature
0.698 0.302 0.000
X20-X29 Contact with venomous animals and plants
0.698 0.302 0.000
X10-X19 Contact with heat and hot substances
0.698 0.302 0.000
X00-X09 Exposure to smoke, fire and flames
0.698 0.302 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.698 0.302 0.000
W75-W84 Other accidental threats to breathing
0.698 0.302 0.000
W65-W74 Accidental drowning and submersion
0.698 0.302 0.000
W50-W64 Exposure to animate mechanical forces
0.698 0.302 0.000
V98-V99 Other and unspecified transport accidents
0.698 0.302 0.000
V95-V97 Air and space transport accidents
0.698 0.302 0.000
V90-V94 Water transport accidents
0.698 0.302 0.000
V80-V89 Other land transport accidents
0.698 0.302 0.000
V70-V79 Bus occupant injured in transport accident
0.698 0.302 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.698 0.302 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.698 0.302 0.000
V40-V49 Car occupant injured in transport accident
0.698 0.302 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.698 0.302 0.000
V01-V09 Pedestrian injured in transport accident
0.698 0.302 0.000
D53 Other nutritional anaemias
0.698 0.302 0.000
D52 Folate deficiency anaemia
0.698 0.302 0.000
E85 Amyloidosis
0.697 0.303 0.000
E84 Cystic fibrosis
0.697 0.303 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.697 0.303 0.000
E79 Disorders of purine and pyrimidine metabolism
0.697 0.303 0.000
E77 Disorders of glycoprotein metabolism
0.697 0.303 0.000
E76 Disorders of glycosaminoglycan metabolism
0.697 0.303 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.697 0.303 0.000
E74 Other disorders of carbohydrate metabolism
0.697 0.303 0.000
E73 Lactose intolerance
0.697 0.303 0.000
E72 Other disorders of amino-acid metabolism
0.697 0.303 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.697 0.303 0.000
E70 Disorders of aromatic amino-acid metabolism
0.697 0.303 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.697 0.303 0.000
J44 Other chronic obstructive pulmonary disease
0.696 0.304 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.696 0.304 0.000
E50-E64 Other nutritional deficiencies
0.696 0.304 0.000
I70 Atherosclerosis
0.696 0.304 0.000
Z52 Donors of organs and tissues
0.696 0.304 0.000
Z44 Fitting and adjustment of external prosthetic device
0.696 0.304 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.695 0.305 0.000
G30-G32 Other degenerative diseases of the nervous system
0.695 0.305 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.694 0.306 0.000
E87.5 Hyperkalaemia
0.693 0.307 0.000
D50.1 Sideropenic dysphagia
0.693 0.307 0.000
M21 Other acquired deformities of limbs
0.692 0.308 0.000
B35-B49 Mycoses
0.691 0.309 0.000
G51 Facial nerve disorders
0.691 0.309 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.690 0.310 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.690 0.310 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.690 0.310 0.000
M33 Dermatopolymyositis
0.690 0.310 0.000
M32 Systemic lupus erythematosus
0.690 0.310 0.000
M30 Polyarteritis nodosa and related conditions
0.690 0.310 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.690 0.310 0.000
E83.8 Other disorders of mineral metabolism
0.690 0.310 0.000
E83.3 Disorders of phosphorus metabolism
0.690 0.310 0.000
E83.2 Disorders of zinc metabolism
0.690 0.310 0.000
E83.0 Disorders of copper metabolism
0.690 0.310 0.000
I44.0 Atrioventricular block, first degree
0.690 0.310 0.000
J30-J39 Other diseases of upper respiratory tract
0.689 0.310 0.000
I42.8 Other cardiomyopathies
0.689 0.311 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.689 0.311 0.000
I42.6 Alcoholic cardiomyopathy
0.689 0.311 0.000
I42.5 Other restrictive cardiomyopathy
0.689 0.311 0.000
I42.4 Endocardial fibroelastosis
0.689 0.311 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.689 0.311 0.000
T93 Sequelae of injuries of lower limb
0.688 0.312 0.000
Z75 Problems related to medical facilities and other health care
0.688 0.312 0.000
Y44 Agents primarily affecting blood constituents
0.688 0.312 0.000
B07 Viral warts
0.687 0.313 0.000
I50.1 Left ventricular failure
0.687 0.313 0.000
I44.3 Other and unspecified atrioventricular block
0.686 0.314 0.000
Z73 Problems related to life-management difficulty
0.685 0.315 0.000
G58 Other mononeuropathies
0.685 0.315 0.000
Y59 Other and unspecified vaccines and biological substances
0.683 0.317 0.000
Y58 Bacterial vaccines
0.683 0.317 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.683 0.317 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.683 0.317 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.683 0.317 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.683 0.317 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.683 0.317 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.683 0.317 0.000
Y48 Anaesthetics and therapeutic gases
0.683 0.317 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.683 0.317 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.683 0.317 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.683 0.317 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.683 0.317 0.000
M51 Other intervertebral disk disorders
0.682 0.318 0.000
J18.1 Lobar pneumonia, unspecified
0.682 0.318 0.000
G35 Multiple sclerosis
0.681 0.319 0.000
M45-M49 Spondylopathies
0.680 0.320 0.000
I51.9 Heart disease, unspecified
0.680 0.320 0.000
I47.0 Reentry ventricular arrhythmia
0.680 0.320 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.679 0.321 0.000
Z50.6 Orthoptic training
0.679 0.321 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.679 0.321 0.000
Z50.3 Drug rehabilitation
0.679 0.321 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.679 0.321 0.000
M25.8 Other specified joint disorders
0.678 0.322 0.000
Z72.9 Problem related to lifestyle, unspecified
0.678 0.322 0.000
Z72.8 Other problems related to lifestyle
0.678 0.322 0.000
Z72.6 Gambling and betting
0.678 0.322 0.000
Z72.5 High-risk sexual behaviour
0.678 0.322 0.000
Z72.4 Inappropriate diet and eating habits
0.678 0.322 0.000
Z72.3 Lack of physical exercise
0.678 0.322 0.000
Z72.2 Drug use
0.678 0.322 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.677 0.323 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.675 0.325 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.674 0.326 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.674 0.326 0.000
O85-O92 Complications predominantly related to the puerperium
0.674 0.326 0.000
M25.4 Effusion of joint
0.673 0.327 0.000
I05-I09 Chronic rheumatic heart diseases
0.673 0.327 0.000
S70 Superficial injury of hip and thigh
0.673 0.327 0.000
Y40 Systemic antibiotics
0.672 0.328 0.000
T78.2 Anaphylactic shock, unspecified
0.672 0.328 0.000
S72.1 Pertrochanteric fracture
0.672 0.328 0.000
I33.0 Acute and subacute infective endocarditis
0.671 0.329 0.000
M25.9 Joint disorder, unspecified
0.671 0.329 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.671 0.329 0.000
M25.3 Other instability of joint
0.671 0.329 0.000
M25.2 Flail joint
0.671 0.329 0.000
M25.1 Fistula of joint
0.671 0.329 0.000
M25.0 Haemarthrosis
0.671 0.329 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.671 0.329 0.000
G62 Other polyneuropathies
0.670 0.330 0.000
J21 Acute bronchiolitis
0.670 0.330 0.000
J20 Acute bronchitis
0.670 0.330 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.670 0.330 0.000
Z40 Prophylactic surgery
0.670 0.330 0.000
E87.2 Acidosis
0.669 0.331 0.000
B99-B99 Other infectious diseases
0.668 0.332 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.668 0.332 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.668 0.332 0.000
B65-B83 Helminthiases
0.668 0.332 0.000
B50-B64 Protozoal diseases
0.668 0.332 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.668 0.332 0.000
B15-B19 Viral hepatitis
0.668 0.332 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.668 0.332 0.000
A75-A79 Rickettsioses
0.668 0.332 0.000
A70-A74 Other diseases caused by chlamydiae
0.668 0.332 0.000
A65-A69 Other spirochaetal diseases
0.668 0.332 0.000
A20-A28 Certain zoonotic bacterial diseases
0.668 0.332 0.000
A15-A19 Tuberculosis
0.668 0.332 0.000
Y57 Other and unspecified drugs and medicaments
0.667 0.333 0.000
J92 Pleural plaque
0.667 0.333 0.000
E87.0 Hyperosmolality and hypernatraemia
0.666 0.333 0.000
W00-W19 Falls
0.666 0.334 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.665 0.335 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.664 0.336 0.000
M50 Cervical disk disorders
0.662 0.338 0.000
G70-G73 Diseases of myoneural junction and muscle
0.661 0.338 0.000
X60-X84 Intentional self-harm
0.661 0.339 0.000
O80 Single spontaneous delivery
0.661 0.339 0.000
M20 Acquired deformities of fingers and toes
0.661 0.339 0.000
M25.74 Osteophyte (Hand)
0.661 0.339 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.660 0.340 0.000
E87.4 Mixed disorder of acid-base balance
0.660 0.340 0.000
E87.3 Alkalosis
0.660 0.340 0.000
I72.0 Aneurysm of carotid artery
0.659 0.340 0.000
S72.4 Fracture of lower end of femur
0.659 0.341 0.000
E27 Other disorders of adrenal gland
0.659 0.341 0.000
M31.6 Other giant cell arteritis
0.658 0.342 0.000
E23 Hypofunction and other disorders of pituitary gland
0.658 0.342 0.000
E28 Ovarian dysfunction
0.657 0.343 0.000
M22 Disorders of patella
0.657 0.343 0.000
Q60-Q64 Congenital malformations of the urinary system
0.656 0.344 0.000
T86 Failure and rejection of transplanted organs and tissues
0.656 0.344 0.000
I77.1 Stricture of artery
0.655 0.345 0.000
Y43.9 Primarily systemic agent, unspecified
0.655 0.345 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.655 0.345 0.000
Y43.6 Enzymes, not elsewhere classified
0.655 0.345 0.000
Y43.5 Acidifying and alkalising agents
0.655 0.345 0.000
Y43.4 Immunosuppressive agents
0.655 0.345 0.000
Y43.2 Antineoplastic natural products
0.655 0.345 0.000
Y43.1 Antineoplastic antimetabolites
0.655 0.345 0.000
Y43.0 Antiallergic and antiemetic drugs
0.655 0.345 0.000
M53 Other dorsopathies, not elsewhere classified
0.654 0.345 0.000
T85.2 Mechanical complication of intraocular lens
0.653 0.347 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.652 0.348 0.000
S42 Fracture of shoulder and upper arm
0.651 0.349 0.000
I71 Aortic aneurysm and dissection
0.651 0.349 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.650 0.350 0.000
E34 Other endocrine disorders
0.650 0.350 0.000
E32 Diseases of thymus
0.650 0.350 0.000
E31 Polyglandular dysfunction
0.650 0.350 0.000
E30 Disorders of puberty, not elsewhere classified
0.650 0.350 0.000
E29 Testicular dysfunction
0.650 0.350 0.000
E26 Hyperaldosteronism
0.650 0.350 0.000
E25 Adrenogenital disorders
0.650 0.350 0.000
E24 Cushing's syndrome
0.650 0.350 0.000
E22 Hyperfunction of pituitary gland
0.650 0.350 0.000
E20 Hypoparathyroidism
0.650 0.350 0.000
M80-M85 Disorders of bone density and structure
0.649 0.351 0.000
J81 Pulmonary oedema
0.649 0.351 0.000
S59 Other and unspecified injuries of forearm
0.648 0.351 0.000
S58 Traumatic amputation of forearm
0.648 0.351 0.000
S57 Crushing injury of forearm
0.648 0.351 0.000
S56 Injury of muscle and tendon at forearm level
0.648 0.351 0.000
S55 Injury of blood vessels at forearm level
0.648 0.351 0.000
S54 Injury of nerves at forearm level
0.648 0.351 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.648 0.351 0.000
S50 Superficial injury of forearm
0.648 0.351 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.648 0.352 0.000
T75 Effects of other external causes
0.647 0.353 0.000
T74 Maltreatment syndromes
0.647 0.353 0.000
T73 Effects of other deprivation
0.647 0.353 0.000
T70 Effects of air pressure and water pressure
0.647 0.353 0.000
T69 Other effects of reduced temperature
0.647 0.353 0.000
T67 Effects of heat and light
0.647 0.353 0.000
T71 Asphyxiation
0.647 0.353 0.000
T66 Unspecified effects of radiation
0.647 0.353 0.000
O21 Excessive vomiting in pregnancy
0.647 0.353 0.000
I46.9 Cardiac arrest, unspecified
0.647 0.353 0.000
T87 Complications peculiar to reattachment and amputation
0.647 0.353 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.647 0.353 0.000
M25.71 Osteophyte (Shoulder region)
0.647 0.353 0.000
G54 Nerve root and plexus disorders
0.646 0.354 0.000
L89 Decubitus ulcer
0.646 0.354 0.000
S64 Injury of nerves at wrist and hand level
0.646 0.354 0.000
O20 Haemorrhage in early pregnancy
0.646 0.354 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.645 0.355 0.000
J94 Other pleural conditions
0.645 0.355 0.000
I38 Endocarditis, valve unspecified
0.644 0.355 0.000
I49 Other cardiac arrhythmias
0.644 0.356 0.000
Chapter VII Diseases of the eye and adnexa
0.643 0.357 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.642 0.358 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.642 0.358 0.000
O24 Diabetes mellitus in pregnancy
0.641 0.358 0.000
M25.78 Osteophyte (Other)
0.641 0.358 0.000
S60 Superficial injury of wrist and hand
0.641 0.359 0.000
J70 Respiratory conditions due to other external agents
0.641 0.359 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.641 0.359 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.641 0.359 0.000
J66 Airway disease due to specific organic dust
0.641 0.359 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.641 0.359 0.000
J62 Pneumoconiosis due to dust containing silica
0.641 0.359 0.000
J65 Pneumoconiosis associated with tuberculosis
0.641 0.359 0.000
J64 Unspecified pneumoconiosis
0.641 0.359 0.000
J60 Coalworker's pneumoconiosis
0.641 0.359 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.639 0.361 0.000
S79 Other and unspecified injuries of hip and thigh
0.639 0.361 0.000
S78 Traumatic amputation of hip and thigh
0.639 0.361 0.000
S77 Crushing injury of hip and thigh
0.639 0.361 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.639 0.361 0.000
S75 Injury of blood vessels at hip and thigh level
0.639 0.361 0.000
S74 Injury of nerves at hip and thigh level
0.639 0.361 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.639 0.361 0.000
S71 Open wound of hip and thigh
0.639 0.361 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.639 0.361 0.000
J80 Adult respiratory distress syndrome
0.639 0.361 0.000
Q00-Q07 Congenital malformations of the nervous system
0.638 0.362 0.000
L57.0 Actinic keratosis
0.638 0.362 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.637 0.363 0.000
Z47.9 Orthopaedic follow-up care, unspecified
0.636 0.363 0.000
M25.57 Pain in joint (Ankle and foot)
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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