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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

Affx-28402786
log Bayes Factor = 40.5138
Chromosome 6   position 29,555,809  (GRCh37) Explore Affx-28402786 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.004 0.996
E10.1 With ketoacidosis
0.000 0.034 0.966
E10.4 With neurological complications
0.000 0.044 0.956
E13 Other specified diabetes mellitus
0.000 0.054 0.946
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.054 0.946
E16 Other disorders of pancreatic internal secretion
0.000 0.055 0.945
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.055 0.945
E16.2 Hypoglycaemia, unspecified
0.000 0.055 0.945
E20-E35 Disorders of other endocrine glands
0.000 0.087 0.913
E10.2 With renal complications
0.000 0.088 0.912
E13.9 Without complications
0.000 0.090 0.910
E10.6 With other specified complications
0.000 0.100 0.900
E23 Hypofunction and other disorders of pituitary gland
0.000 0.100 0.900
E14 Unspecified diabetes mellitus
0.000 0.105 0.895
E10.0 With coma
0.000 0.126 0.874
E23.0 Hypopituitarism
0.000 0.133 0.867
E24 Cushing's syndrome
0.000 0.135 0.865
K51.9 Ulcerative colitis, unspecified
0.865 0.135 0.000
K51 Ulcerative colitis
0.853 0.147 0.000
E10.5 With peripheral circulatory complications
0.000 0.153 0.847
K51.4 Pseudopolyposis of colon
0.833 0.167 0.000
E16.1 Other hypoglycaemia
0.000 0.181 0.819
E14.3 With ophthalmic complications
0.000 0.211 0.789
E14.5 With peripheral circulatory complications
0.000 0.214 0.786
E23.7 Disorder of pituitary gland, unspecified
0.000 0.225 0.775
E11 Non-insulin-dependent diabetes mellitus
0.000 0.225 0.775
E24.9 Cushing's syndrome, unspecified
0.000 0.227 0.773
E10.7 With multiple complications
0.000 0.229 0.771
E23.2 Diabetes insipidus
0.000 0.235 0.765
E24.0 Pituitary-dependent Cushing's disease
0.000 0.238 0.762
K51.8 Other ulcerative colitis
0.760 0.240 0.000
K51.2 Ulcerative (chronic) proctitis
0.715 0.285 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.714
E25 Adrenogenital disorders
0.000 0.295 0.705
K51.5 Mucosal proctocolitis
0.696 0.304 0.000
E11.1 With ketoacidosis
0.000 0.313 0.687
E13.8 With unspecified complications
0.000 0.321 0.678
E13.7 With multiple complications
0.000 0.321 0.678
E13.6 With other specified complications
0.000 0.321 0.678
E13.5 With peripheral circulatory complications
0.000 0.321 0.678
E13.4 With neurological complications
0.000 0.321 0.678
E13.3 With ophthalmic complications
0.000 0.321 0.678
E13.2 With renal complications
0.000 0.321 0.678
E13.1 With ketoacidosis
0.000 0.321 0.678
E13.0 With coma
0.000 0.321 0.678
E24.2 Drug-induced Cushing's syndrome
0.000 0.322 0.678
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.322 0.677
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.322 0.677
E16.4 Abnormal secretion of gastrin
0.000 0.322 0.677
E16.3 Increased secretion of glucagon
0.000 0.322 0.677
E15 Nondiabetic hypoglycaemic coma
0.000 0.322 0.677
E14.1 With ketoacidosis
0.000 0.331 0.669
E20 Hypoparathyroidism
0.000 0.332 0.668
E14.6 With other specified complications
0.000 0.341 0.659
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.345 0.655
E32 Diseases of thymus
0.000 0.345 0.655
E30 Disorders of puberty, not elsewhere classified
0.000 0.345 0.655
E11.2 With renal complications
0.000 0.346 0.654
E14.4 With neurological complications
0.000 0.348 0.652
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.355 0.645
E23.1 Drug-induced hypopituitarism
0.000 0.355 0.645
E14.7 With multiple complications
0.000 0.358 0.642
E14.0 With coma
0.000 0.358 0.642
E14.2 Withrenal complications
0.000 0.370 0.630
E29 Testicular dysfunction
0.000 0.373 0.627
E11.0 With coma
0.000 0.373 0.627
E31 Polyglandular dysfunction
0.000 0.377 0.623
E34 Other endocrine disorders
0.000 0.379 0.621
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.380 0.620
E24.3 Ectopic ACTH syndrome
0.000 0.380 0.620
E24.1 Nelson's syndrome
0.000 0.380 0.620
K51.3 Ulcerative (chronic) rectosigmoiditis
0.619 0.381 0.000
E11.8 With unspecified complications
0.000 0.383 0.616
K51.0 Ulcerative (chronic) enterocolitis
0.612 0.388 0.000
E23.6 Other disorders of pituitary gland
0.000 0.390 0.610
E11.6 With other specified complications
0.000 0.394 0.605
E28 Ovarian dysfunction
0.000 0.407 0.593
E11.5 With peripheral circulatory complications
0.000 0.411 0.589
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.420 0.580
K51.1 Ulcerative (chronic) ileocolitis
0.578 0.422 0.000
E24.8 Other Cushing's syndrome
0.000 0.422 0.578
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.444 0.556
E26 Hyperaldosteronism
0.000 0.444 0.555
E11.7 With multiple complications
0.000 0.444 0.555
E14.8 With unspecified complications
0.000 0.446 0.554
E14.9 Without complications
0.000 0.465 0.535
E40-E46 Malnutrition
0.000 0.480 0.520
E12.9 Without complications
0.000 0.488 0.512
E12.8 With unspecified complications
0.000 0.488 0.512
E12.7 With multiple complications
0.000 0.488 0.512
E12.6 With other specified complications
0.000 0.488 0.512
E12.5 With peripheral circulatory complications
0.000 0.488 0.512
E12.4 With neurological complications
0.000 0.488 0.512
E12.3 With ophthalmic complications
0.000 0.488 0.512
E12.2 With renal complications
0.000 0.488 0.512
E12.1 With ketoacidosis
0.000 0.488 0.512
E12.0 With coma
0.000 0.488 0.512
E50-E64 Other nutritional deficiencies
0.000 0.489 0.510
E25.9 Adrenogenital disorder, unspecified
0.000 0.494 0.505
E25.8 Other adrenogenital disorders
0.000 0.494 0.505
E10.8 With unspecified complications
0.000 0.498 0.502
E34.8 Other specified endocrine disorders
0.000 0.501 0.499
E27 Other disorders of adrenal gland
0.000 0.505 0.495
E20.9 Hypoparathyroidism, unspecified
0.000 0.508 0.492
E20.8 Other hypoparathyroidism
0.000 0.521 0.479
E20.1 Pseudohypoparathyroidism
0.000 0.521 0.479
E20.0 Idiopathic hypoparathyroidism
0.000 0.521 0.479
E00-E07 Disorders of thyroid gland
0.000 0.527 0.473
E30.9 Disorder of puberty, unspecified
0.000 0.530 0.469
E30.8 Other disorders of puberty
0.000 0.530 0.469
E30.1 Precocious puberty
0.000 0.530 0.469
E30.0 Delayed puberty
0.000 0.530 0.469
E32.9 Disease of thymus, unspecified
0.000 0.530 0.469
E32.8 Other diseases of thymus
0.000 0.530 0.469
E32.1 Abscess of thymus
0.000 0.530 0.469
E32.0 Persistent hyperplasia of thymus
0.000 0.530 0.469
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.530 0.469
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.530 0.469
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.530 0.469
E22 Hyperfunction of pituitary gland
0.000 0.531 0.469
E83 Disorders of mineral metabolism
0.468 0.532 0.000
E28.3 Primary ovarian failure
0.000 0.538 0.462
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.543 0.457
E34.3 Short stature, not elsewhere classified
0.000 0.546 0.454
E29.9 Testicular dysfunction, unspecified
0.000 0.550 0.450
E29.8 Other testicular dysfunction
0.000 0.550 0.450
E29.0 Testicular hyperfunction
0.000 0.550 0.450
E31.9 Polyglandular dysfunction, unspecified
0.000 0.553 0.446
E31.8 Other polyglandular dysfunction
0.000 0.553 0.446
E31.1 Polyglandular hyperfunction
0.000 0.553 0.446
E34.5 Androgen resistance syndrome
0.000 0.554 0.445
E34.4 Constitutional tall stature
0.000 0.554 0.445
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.554 0.445
E34.1 Other hypersecretion of intestinal hormones
0.000 0.554 0.445
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.563 0.437
E28.9 Ovarian dysfunction, unspecified
0.000 0.574 0.425
E28.8 Other ovarian dysfunction
0.000 0.574 0.425
E28.1 Androgen excess
0.000 0.574 0.425
E28.0 Oestrogen excess
0.000 0.574 0.425
E29.1 Testicular hypofunction
0.000 0.578 0.422
E05.9 Thyrotoxicosis, unspecified
0.000 0.578 0.422
E11.4 With neurological complications
0.000 0.582 0.418
E31.0 Autoimmune polyglandular failure
0.000 0.585 0.414
E34.9 Endocrine disorder, unspecified
0.000 0.587 0.413
E83.4 Disorders of magnesium metabolism
0.412 0.588 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.593 0.407
E26.9 Hyperaldosteronism, unspecified
0.000 0.593 0.406
E61 Deficiency of other nutrient elements
0.000 0.598 0.402
E26.8 Other hyperaldosteronism
0.000 0.601 0.398
E26.1 Secondary hyperaldosteronism
0.000 0.601 0.398
E27.8 Other specified disorders of adrenal gland
0.000 0.607 0.393
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.622 0.377
E27.9 Disorder of adrenal gland, unspecified
0.000 0.626 0.374
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.627 0.373
E45 Retarded development following protein-energy malnutrition
0.000 0.627 0.373
E43 Unspecified severe protein-energy malnutrition
0.000 0.627 0.373
E42 Marasmic kwashiorkor
0.000 0.627 0.373
E41 Nutritional marasmus
0.000 0.627 0.373
E40 Kwashiorkor
0.000 0.627 0.373
E05.8 Other thyrotoxicosis
0.000 0.629 0.371
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.634 0.366
E63 Other nutritional deficiencies
0.000 0.634 0.366
E50 Vitamin A deficiency
0.000 0.634 0.366
E60 Dietary zinc deficiency
0.000 0.634 0.366
E59 Dietary selenium deficiency
0.000 0.634 0.366
E54 Ascorbic acid deficiency
0.000 0.634 0.366
E52 Niacin deficiency [pellagra]
0.000 0.634 0.366
E21.3 Hyperparathyroidism, unspecified
0.000 0.638 0.362
E51 Thiamine deficiency
0.000 0.639 0.360
E83.3 Disorders of phosphorus metabolism
0.359 0.641 0.000
E56 Other vitamin deficiencies
0.000 0.641 0.359
E27.5 Adrenomedullary hyperfunction
0.000 0.645 0.355
E27.0 Other adrenocortical overactivity
0.000 0.645 0.355
E34.0 Carcinoid syndrome
0.000 0.645 0.354
E65-E68 Obesity and other hyperalimentation
0.000 0.652 0.348
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.661 0.339
E00 Congenital iodine-deficiency syndrome
0.000 0.661 0.339
E22.8 Other hyperfunction of pituitary gland
0.000 0.663 0.336
E83.8 Other disorders of mineral metabolism
0.335 0.665 0.000
E83.2 Disorders of zinc metabolism
0.335 0.665 0.000
E83.0 Disorders of copper metabolism
0.335 0.665 0.000
E22.1 Hyperprolactinaemia
0.000 0.667 0.333
E58 Dietary calcium deficiency
0.000 0.668 0.331
E61.1 Iron deficiency
0.000 0.670 0.330
E05.5 Thyroid crisis or storm
0.000 0.672 0.327
E05.4 Thyrotoxicosis factitia
0.000 0.672 0.327
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.672 0.327
E55 Vitamin D deficiency
0.000 0.673 0.327
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.676 0.324
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.677 0.323
E83.9 Disorder of mineral metabolism, unspecified
0.319 0.681 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.686 0.314
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.689 0.311
E22.0 Acromegaly and pituitary gigantism
0.000 0.690 0.309
E21.2 Other hyperparathyroidism
0.000 0.691 0.308
K90 Intestinal malabsorption
0.000 0.696 0.304
E28.2 Polycystic ovarian syndrome
0.000 0.700 0.300
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.700 0.300
E11.3 With ophthalmic complications
0.000 0.702 0.298
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.704 0.296
E61.9 Deficiency of nutrient element, unspecified
0.000 0.712 0.288
E61.8 Deficiency of other specified nutrient elements
0.000 0.712 0.288
E61.7 Deficiency of multiple nutrient elements
0.000 0.712 0.288
E61.6 Vanadium deficiency
0.000 0.712 0.288
E61.5 Molybdenum deficiency
0.000 0.712 0.288
E61.4 Chromium deficiency
0.000 0.712 0.288
E61.3 Manganese deficiency
0.000 0.712 0.288
E61.0 Copper deficiency
0.000 0.712 0.288
E26.0 Primary hyperaldosteronism
0.000 0.714 0.285
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.716 0.284
E07 Other disorders of thyroid
0.000 0.716 0.283
E61.2 Magnesium deficiency
0.000 0.721 0.279
E53 Deficiency of other B group vitamins
0.000 0.731 0.269
E44.1 Mild protein-energy malnutrition
0.000 0.732 0.267
E44.0 Moderate protein-energy malnutrition
0.000 0.732 0.267
E50.9 Vitamin A deficiency, unspecified
0.000 0.737 0.263
E50.8 Other manifestations of vitamin A deficiency
0.000 0.737 0.263
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.737 0.263
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.737 0.263
E50.5 Vitamin A deficiency with night blindness
0.000 0.737 0.263
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.737 0.263
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.737 0.263
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.737 0.263
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.737 0.263
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.737 0.263
E63.9 Nutritional deficiency, unspecified
0.000 0.737 0.263
E63.8 Other specified nutritional deficiencies
0.000 0.737 0.263
E63.1 Imbalance of constituents of food intake
0.000 0.737 0.263
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.737 0.263
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.737 0.263
E64.8 Sequelae of other nutritional deficiencies
0.000 0.737 0.263
E64.3 Sequelae of rickets
0.000 0.737 0.263
E64.2 Sequelae of vitamin C deficiency
0.000 0.737 0.263
E64.1 Sequelae of vitamin A deficiency
0.000 0.737 0.263
E64.0 Sequelae of protein-energy malnutrition
0.000 0.737 0.263
E27.1 Primary adrenocortical insufficiency
0.000 0.740 0.259
E51.9 Thiamine deficiency, unspecified
0.000 0.741 0.259
E51.8 Other manifestations of thiamine deficiency
0.000 0.741 0.259
E51.1 Beriberi
0.000 0.741 0.259
E56.9 Vitamin deficiency, unspecified
0.000 0.742 0.258
E56.8 Deficiency of other vitamins
0.000 0.742 0.258
E56.0 Deficiency of vitamin E
0.000 0.742 0.258
E51.2 Wernicke's encephalopathy
0.000 0.747 0.253
E27.2 Addisonian crisis
0.000 0.747 0.253
K50-K52 Noninfective enteritis and colitis
0.252 0.748 0.000
E56.1 Deficiency of vitamin K
0.000 0.749 0.251
E67 Other hyperalimentation
0.000 0.751 0.249
E68 Sequelae of hyperalimentation
0.000 0.751 0.249
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.755 0.244
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.757 0.243
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.757 0.243
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.757 0.243
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.757 0.243
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.757 0.243
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.757 0.243
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.757 0.243
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.757 0.243
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.765 0.235
E55.0 Rickets, active
0.000 0.766 0.234
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.766 0.234
E07.8 Other specified disorders of thyroid
0.000 0.778 0.222
K90.3 Pancreatic steatorrhoea
0.000 0.782 0.218
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.782 0.218
K90.1 Tropical sprue
0.000 0.782 0.218
K50 Crohn's disease [regional enteritis]
0.215 0.785 0.000
E06 Thyroiditis
0.000 0.785 0.215
E46 Unspecified protein-energy malnutrition
0.000 0.785 0.215
E65 Localised adiposity
0.000 0.795 0.205
K90.8 Other intestinal malabsorption
0.000 0.795 0.205
E07.1 Dyshormogenetic goitre
0.000 0.797 0.203
E07.0 Hypersecretion of calcitonin
0.000 0.797 0.203
K50.9 Crohn's disease, unspecified
0.203 0.797 0.000
E03 Other hypothyroidism
0.000 0.799 0.200
E55.9 Vitamin D deficiency, unspecified
0.000 0.805 0.195
E53.1 Pyridoxine deficiency
0.000 0.807 0.193
E53.0 Riboflavin deficiency
0.000 0.807 0.193
E53.9 Vitamin B deficiency, unspecified
0.000 0.815 0.185
K50.1 Crohn's disease of large intestine
0.181 0.819 0.000
E67.8 Other specified hyperalimentation
0.000 0.821 0.179
E67.3 Hypervitaminosis D
0.000 0.821 0.179
E67.2 Megavitamin-B6 syndrome
0.000 0.821 0.179
E67.1 Hypercarotenaemia
0.000 0.821 0.179
E67.0 Hypervitaminosis A
0.000 0.821 0.179
E03.8 Other specified hypothyroidism
0.000 0.838 0.162
E83.5 Disorders of calcium metabolism
0.159 0.841 0.000
E06.9 Thyroiditis, unspecified
0.000 0.841 0.158
E21.0 Primary hyperparathyroidism
0.000 0.841 0.159
E06.4 Drug-induced thyroiditis
0.000 0.845 0.154
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.845 0.154
E06.1 Subacute thyroiditis
0.000 0.845 0.154
E06.0 Acute thyroiditis
0.000 0.845 0.154
E03.5 Myxoedema coma
0.000 0.856 0.144
E03.4 Atrophy of thyroid (acquired)
0.000 0.856 0.144
E03.3 Postinfectious hypothyroidism
0.000 0.856 0.144
E03.1 Congenital hypothyroidism without goitre
0.000 0.856 0.144
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.856 0.144
K90.9 Intestinal malabsorption, unspecified
0.000 0.856 0.144
E06.5 Other chronic thyroiditis
0.000 0.856 0.143
E11.9 Without complications
0.000 0.867 0.133
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.880 0.120
K50.8 Other Crohn's disease
0.113 0.887 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.888 0.112
E07.9 Disorder of thyroid, unspecified
0.000 0.894 0.105
K50.0 Crohn's disease of small intestine
0.087 0.913 0.000
E66 Obesity
0.000 0.948 0.052
E70-E90 Metabolic disorders
0.048 0.949 0.003
E06.3 Autoimmune thyroiditis
0.001 0.953 0.046
H40.2 Primary angle-closure glaucoma
0.046 0.954 0.000
E85 Amyloidosis
0.043 0.956 0.001
E04 Other non-toxic goitre
0.000 0.956 0.043
E85.9 Amyloidosis, unspecified
0.038 0.961 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.038 0.962 0.000
E70 Disorders of aromatic amino-acid metabolism
0.036 0.962 0.002
E66.1 Drug-induced obesity
0.000 0.963 0.037
E85.3 Secondary systemic amyloidosis
0.037 0.963 0.001
E84 Cystic fibrosis
0.035 0.963 0.002
E77 Disorders of glycoprotein metabolism
0.035 0.963 0.002
E76 Disorders of glycosaminoglycan metabolism
0.035 0.963 0.002
E72 Other disorders of amino-acid metabolism
0.035 0.963 0.002
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.035 0.963 0.002
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.035 0.963 0.002
H40 Glaucoma
0.037 0.963 0.000
E74 Other disorders of carbohydrate metabolism
0.034 0.965 0.002
H40.5 Glaucoma secondary to other eye disorders
0.035 0.965 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.034 0.965 0.001
E79 Disorders of purine and pyrimidine metabolism
0.033 0.965 0.002
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.030 0.968 0.002
E85.2 Heredofamilial amyloidosis, unspecified
0.031 0.968 0.001
E85.1 Neuropathic heredofamilial amyloidosis
0.031 0.968 0.001
E85.0 Nonneuropathic heredofamilial amyloidosis
0.031 0.968 0.001
E85.8 Other amyloidosis
0.031 0.968 0.001
H40.0 Glaucoma suspect
0.032 0.968 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.968 0.032
E04.8 Other specified non-toxic goitre
0.000 0.968 0.031
E66.0 Obesity due to excess calories
0.000 0.969 0.031
E89.5 Postprocedural testicular hypofunction
0.030 0.970 0.000
E89.4 Postprocedural ovarian failure
0.029 0.970 0.000
E88 Other metabolic disorders
0.028 0.970 0.002
E85.4 Organ-limited amyloidosis
0.029 0.971 0.001
H40.3 Glaucoma secondary to eye trauma
0.029 0.971 0.000
E89.1 Postprocedural hypoinsulinaemia
0.029 0.971 0.000
E80.1 Porphyria cutanea tarda
0.028 0.971 0.001
E70.3 Albinism
0.027 0.972 0.001
E73 Lactose intolerance
0.026 0.972 0.002
E86 Volume depletion
0.028 0.972 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.027 0.972 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.027 0.972 0.000
E89.2 Postprocedural hypoparathyroidism
0.028 0.972 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.027 0.972 0.001
H40.4 Glaucoma secondary to eye inflammation
0.027 0.972 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.026 0.973 0.001
E70.8 Other disorders of aromatic amino-acid metabolism
0.026 0.973 0.001
E70.2 Disorders of tyrosine metabolism
0.026 0.973 0.001
E70.1 Other hyperphenylalaninaemias
0.026 0.973 0.001
E70.0 Classical phenylketonuria
0.026 0.973 0.001
E89.0 Postprocedural hypothyroidism
0.027 0.973 0.000
E84.9 Cystic fibrosis, unspecified
0.026 0.973 0.001
L40.9 Psoriasis, unspecified
0.000 0.973 0.027
E04.9 Non-toxic goitre, unspecified
0.000 0.973 0.027
H40.8 Other glaucoma
0.027 0.973 0.000
E84.8 Cystic fibrosis with other manifestations
0.025 0.973 0.002
E84.1 Cystic fibrosis with intestinal manifestations
0.025 0.973 0.002
E84.0 Cystic fibrosis with pulmonary manifestations
0.025 0.973 0.002
E89.3 Postprocedural hypopituitarism
0.027 0.973 0.000
E71.3 Disorders of fatty-acid metabolism
0.025 0.973 0.002
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.025 0.973 0.002
E71.1 Other disorders of branched-chain amino-acid metabolism
0.025 0.973 0.002
E71.0 Maple-syrup-urine disease
0.025 0.973 0.002
E72.9 Disorder of amino-acid metabolism, unspecified
0.025 0.973 0.002
E72.8 Other specified disorders of amino-acid metabolism
0.025 0.973 0.002
E72.5 Disorders of glycine metabolism
0.025 0.973 0.002
E72.4 Disorders of ornithine metabolism
0.025 0.973 0.002
E72.3 Disorders of lysine and hydroxylysine metabolism
0.025 0.973 0.002
E72.2 Disorders of urea cycle metabolism
0.025 0.973 0.002
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.025 0.973 0.002
E72.0 Disorders of amino-acid transport
0.025 0.973 0.002
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.025 0.973 0.002
E76.8 Other disorders of glucosaminoglycan metabolism
0.025 0.973 0.002
E76.3 Mucopolysaccharidosis, unspecified
0.025 0.973 0.002
E76.2 Other mucopolysaccharidoses
0.025 0.973 0.002
E76.1 Mucopolysaccharidosis, type II
0.025 0.973 0.002
E76.0 Mucopolysaccharidosis, type I
0.025 0.973 0.002
E77.9 Disorder of glycoprotein metabolism, unspecified
0.025 0.973 0.002
E77.8 Other disorders of glycoprotein metabolism
0.025 0.973 0.002
E77.1 Defects in glycoprotein degradation
0.025 0.973 0.002
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.025 0.973 0.002
H40.6 Glaucoma secondary to drugs
0.026 0.973 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.026 0.973 0.000
E80.6 Other disorders of bilirubin metabolism
0.025 0.974 0.001
E74.9 Disorder of carbohydrate metabolism, unspecified
0.024 0.974 0.001
E74.8 Other specified disorders of carbohydrate metabolism
0.024 0.974 0.001
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.024 0.974 0.001
E74.2 Disorders of galactose metabolism
0.024 0.974 0.001
E74.1 Disorders of fructose metabolism
0.024 0.974 0.001
E74.0 Glycogen storage disease
0.024 0.975 0.001
E80.5 Crigler-Najjar syndrome
0.025 0.975 0.001
E80.3 Defects of catalase and peroxydase
0.025 0.975 0.001
E80.0 Hereditary erythropoietic porphyria
0.025 0.975 0.001
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.024 0.975 0.002
E79.8 Other disorders of purine and pyrimidine metabolism
0.024 0.975 0.002
E79.1 Lesch-Nyhan syndrome
0.024 0.975 0.002
E80.2 Other porphyria
0.024 0.975 0.001
E74.3 Other disorders of intestinal carbohydrate absorption
0.023 0.975 0.001
E88.8 Other specified metabolic disorders
0.023 0.976 0.001
E75.6 Lipid storage disorder, unspecified
0.022 0.977 0.002
E75.4 Neuronal ceroid lipofuscinosis
0.022 0.977 0.002
E75.3 Sphingolipidosis, unspecified
0.022 0.977 0.002
E75.1 Other gangliosidosis
0.022 0.977 0.002
E75.0 GM2 gangliosidosis
0.022 0.977 0.002
E75.2 Other sphingolipidosis
0.022 0.977 0.002
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.022 0.977 0.002
E88.3 Tumour lysis syndrome
0.022 0.977 0.001
H40.9 Glaucoma, unspecified
0.023 0.977 0.000
E66.8 Other obesity
0.000 0.979 0.021
I78.1 Naevus, nonneoplastic
0.021 0.979 0.000
E73.8 Other lactose intolerance
0.019 0.979 0.002
E73.1 Secondary lactase deficiency
0.019 0.979 0.002
E73.0 Congenital lactase deficiency
0.019 0.979 0.002
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.020 0.979 0.001
E75.5 Other lipid storage disorders
0.017 0.981 0.002
E88.1 Lipodystrophy, not elsewhere classified
0.017 0.981 0.002
E88.9 Metabolic disorder, unspecified
0.017 0.982 0.002
K90-K93 Other diseases of the digestive system
0.000 0.982 0.018
H40-H42 Glaucoma
0.015 0.985 0.000
E04.0 Non-toxic diffuse goitre
0.001 0.985 0.014
H54.0 Blindness, both eyes
0.000 0.985 0.015
E88.2 Lipomatosis, not elsewhere classified
0.013 0.985 0.002
E04.1 Non-toxic single thyroid nodule
0.000 0.986 0.014
E80.4 Gilbert's syndrome
0.013 0.986 0.000
K52 Other non-infective gastro-enteritis and colitis
0.013 0.987 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.987 0.013
S62.30 Fracture of other metacarpal bone (closed)
0.000 0.987 0.013
E73.9 Lactose intolerance, unspecified
0.010 0.988 0.002
Q23.1 Congenital insufficiency of aortic valve
0.012 0.988 0.000
H54 Blindness and low vision
0.000 0.988 0.012
Q23 Congenital malformations of aortic and mitral valves
0.011 0.989 0.000
H42 Glaucoma in diseases classified elsewhere
0.011 0.989 0.000
I78 Diseases of capillaries
0.011 0.989 0.000
H54.7 Unspecified visual loss
0.000 0.989 0.011
Q23.0 Congenital stenosis of aortic valve
0.011 0.989 0.000
I78.8 Other diseases of capillaries
0.010 0.990 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.010 0.990 0.000
Q21 Congenital malformations of cardiac septa
0.010 0.990 0.000
Q21.0 Ventricular septal defect
0.010 0.990 0.000
H54.6 Unqualified visual loss, one eye
0.000 0.990 0.010
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.990 0.009
K93.1 Megacolon in Chagas' disease
0.000 0.990 0.009
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.990 0.009
Q20-Q28 Congenital malformations of the circulatory system
0.010 0.990 0.000
L40 Psoriasis
0.000 0.991 0.009
H54.4 Blindness, one eye
0.000 0.991 0.009
I78.9 Disease of capillaries, unspecified
0.009 0.991 0.000
I84.2 Internal haemorrhoids without complication
0.009 0.991 0.000
H54.9 Unspecified visual impairment (binocular)
0.000 0.991 0.009
H54.3 Unqualified visual loss, both eyes
0.000 0.991 0.008
Q21.3 Tetralogy of Fallot
0.008 0.991 0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified
0.008 0.992 0.000
Q23.8 Other congenital malformations of aortic and mitral valves
0.008 0.992 0.000
Q23.4 Hypoplastic left heart syndrome
0.008 0.992 0.000
Q23.3 Congenital mitral insufficiency
0.008 0.992 0.000
Q23.2 Congenital mitral stenosis
0.008 0.992 0.000
H42.8 Glaucoma in other diseases classified elsewhere
0.008 0.992 0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases
0.008 0.992 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.008 0.992 0.000
H54.5 Low vision, one eye
0.000 0.992 0.008
H54.1 Blindness, one eye, low vision, other eye
0.000 0.992 0.008
Q21.9 Congenital malformation of cardiac septum, unspecified
0.008 0.992 0.000
H54.2 Low vision, both eyes
0.000 0.992 0.008
L40.1 Generalised pustular psoriasis
0.000 0.992 0.008
Q26 Congenital malformations of great veins
0.008 0.992 0.000
K52.3 Indeterminate colitis
0.007 0.993 0.000
Q21.8 Other congenital malformations of cardiac septa
0.007 0.993 0.000
Q21.4 Aortopulmonary septal defect
0.007 0.993 0.000
Q21.2 Atrioventricular septal defect
0.007 0.993 0.000
L40.4 Guttate psoriasis
0.000 0.993 0.007
Q27 Other congenital malformations of peripheral vascular system
0.007 0.993 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.007 0.993 0.000
Q28 Other congenital malformations of circulatory system
0.007 0.993 0.000
Q24 Other congenital malformations of heart
0.007 0.993 0.000
V18.0 Driver injured in nontraffic accident
0.007 0.993 0.000
L40.2 Acrodermatitis continua
0.000 0.993 0.007
Q25 Congenital malformations of great arteries
0.007 0.993 0.000
Q21.1 Atrial septal defect
0.007 0.993 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.007 0.993 0.000
L73.2 Hidradenitis suppurativa
0.007 0.993 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.007 0.993 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.993 0.007
Q27.8 Other specified congenital malformations of peripheral vascular system
0.006 0.994 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.006 0.994 0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified
0.006 0.994 0.000
Q24.8 Other specified congenital malformations of heart
0.006 0.994 0.000
I84.1 Internal haemorrhoids with other complications
0.006 0.994 0.000
S62.3 Fracture of other metacarpal bone
0.000 0.994 0.006
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.006 0.994 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.000 0.994 0.006

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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