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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10162934
log Bayes Factor = 7.83475
Chromosome 15   position 35,541,843  (GRCh37) Explore rs10162934 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
M20-M25 Other joint disorders
0.995 0.005 0.000
S00-S09 Injuries to the head
0.988 0.012 0.000
Chapter XXI Factors influencing health status and contact with health services
0.986 0.014 0.000
Chapter V Mental and behavioural disorders
0.980 0.020 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.973 0.027 0.000
S20-S29 Injuries to the thorax
0.969 0.031 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.966 0.034 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.966 0.034 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.961 0.039 0.000
S01 Open wound of head
0.958 0.042 0.000
Chapter IX Diseases of the circulatory system
0.957 0.043 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.953 0.047 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.952 0.048 0.000
M35 Other systemic involvement of connective tissue
0.945 0.055 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.945 0.055 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.944 0.056 0.000
T40.2 Other opioids
0.936 0.064 0.000
M80-M85 Disorders of bone density and structure
0.935 0.065 0.000
S01.9 Open wound of head, part unspecified
0.934 0.066 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.934 0.066 0.000
S22.3 Fracture of rib
0.932 0.068 0.000
I74 Arterial embolism and thrombosis
0.929 0.071 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.927 0.073 0.000
M05-M14 Inflammatory polyarthropathies
0.924 0.075 0.000
Z71.8 Other specified counselling
0.924 0.076 0.000
F10.0 Acute intoxication
0.924 0.076 0.000
I73 Other peripheral vascular diseases
0.919 0.081 0.000
S22.30 Fracture of rib (closed)
0.917 0.083 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.915 0.085 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.915 0.085 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.913 0.087 0.000
X60-X84 Intentional self-harm
0.911 0.089 0.000
M24 Other specific joint derangements
0.911 0.089 0.000
M25 Other joint disorders, not elsewhere classified
0.910 0.090 0.000
M13 Other arthritis
0.901 0.099 0.000
T42.4 Benzodiazepines
0.893 0.107 0.000
Z75 Problems related to medical facilities and other health care
0.890 0.110 0.000
Chapter I Certain infectious and parasitic diseases
0.887 0.113 0.000
F10.1 Harmful use
0.886 0.114 0.000
M13.9 Arthritis, unspecified
0.885 0.115 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.882 0.118 0.000
A30-A49 Other bacterial diseases
0.877 0.123 0.000
M80 Osteoporosis with pathological fracture
0.877 0.123 0.000
M21 Other acquired deformities of limbs
0.876 0.124 0.000
E50-E64 Other nutritional deficiencies
0.871 0.129 0.000
F10.3 Withdrawal state
0.870 0.130 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.868 0.132 0.000
I73.9 Peripheral vascular disease, unspecified
0.868 0.132 0.000
S06 Intracranial injury
0.867 0.133 0.000
M25.7 Osteophyte
0.866 0.134 0.000
A41 Other septicaemia
0.865 0.135 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.864 0.136 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.860 0.140 0.000
M35.0 Sicca syndrome [Sjogren]
0.857 0.143 0.000
S60-S69 Injuries to the wrist and hand
0.857 0.143 0.000
M24.1 Other articular cartilage disorders
0.853 0.147 0.000
M50-M54 Other dorsopathies
0.840 0.160 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.839 0.161 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.838 0.162 0.000
V10-V19 Pedal cyclist injured in transport accident
0.833 0.167 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.832 0.168 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.829 0.171 0.000
I71 Aortic aneurysm and dissection
0.829 0.171 0.000
I74.8 Embolism and thrombosis of other arteries
0.828 0.172 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.826 0.174 0.000
Chapter VIII Diseases of the ear and mastoid process
0.825 0.175 0.000
S05 Injury of eye and orbit
0.825 0.175 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.823 0.177 0.000
W00-W19 Falls
0.820 0.180 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.819 0.181 0.000
E53 Deficiency of other B group vitamins
0.819 0.181 0.000
Y57 Other and unspecified drugs and medicaments
0.819 0.181 0.000
Z60 Problems related to social environment
0.817 0.183 0.000
S50-S59 Injuries to the elbow and forearm
0.816 0.184 0.000
M91-M94 Chondropathies
0.815 0.185 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.815 0.185 0.000
W20-W49 Exposure to inanimate mechanical forces
0.813 0.187 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.806 0.194 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.805 0.195 0.000
S01.2 Open wound of nose
0.804 0.196 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.802 0.198 0.000
I60-I69 Cerebrovascular diseases
0.802 0.198 0.000
Z57 Occupational exposure to risk-factors
0.802 0.198 0.000
H65-H75 Diseases of middle ear and mastoid
0.801 0.199 0.000
M25.78 Osteophyte (Other)
0.800 0.200 0.000
M31 Other necrotising vasculopathies
0.798 0.202 0.000
I05-I09 Chronic rheumatic heart diseases
0.796 0.204 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.795 0.205 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.795 0.205 0.000
A41.9 Septicaemia, unspecified
0.795 0.205 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.795 0.205 0.000
I73.0 Raynaud's syndrome
0.793 0.207 0.000
Z71.4 Alcohol abuse counselling and surveillance
0.793 0.207 0.000
F17.1 Harmful use
0.793 0.207 0.000
I69 Sequelae of cerebrovascular disease
0.792 0.208 0.000
M25.74 Osteophyte (Hand)
0.790 0.210 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.787 0.213 0.000
Z63 Other problems related to primary support group, including family circumstances
0.786 0.214 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.785 0.215 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.785 0.215 0.000
M54 Dorsalgia
0.785 0.215 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.784 0.216 0.000
S22.2 Fracture of sternum
0.783 0.217 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.783 0.217 0.000
E53.8 Deficiency of other specified B group vitamins
0.782 0.218 0.000
M35.8 Other specified systemic involvement of connective tissue
0.780 0.220 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.780 0.220 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.779 0.221 0.000
E70-E90 Metabolic disorders
0.778 0.222 0.000
M34 Systemic sclerosis
0.777 0.223 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.772 0.228 0.000
M35.3 Polymyalgia rheumatica
0.772 0.228 0.000
H66 Suppurative and unspecified otitis media
0.771 0.229 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.770 0.230 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.769 0.231 0.000
M45-M49 Spondylopathies
0.767 0.233 0.000
T79-T79 Certain early complications of trauma
0.767 0.233 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.767 0.233 0.000
Z93 Artificial opening status
0.766 0.234 0.000
Chapter VII Diseases of the eye and adnexa
0.766 0.234 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.765 0.235 0.000
Z45 Adjustment and management of implanted device
0.764 0.236 0.000
V80-V89 Other land transport accidents
0.764 0.236 0.000
T86 Failure and rejection of transplanted organs and tissues
0.764 0.236 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.763 0.237 0.000
M06 Other rheumatoid arthritis
0.763 0.237 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.762 0.238 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.761 0.239 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.759 0.241 0.000
Z95.4 Presence of other heart-valve replacement
0.758 0.242 0.000
T40.4 Other synthetic narcotics
0.758 0.242 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.755 0.245 0.000
Y57.5 X-ray contrast media
0.754 0.246 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.753 0.247 0.000
S10-S19 Injuries to the neck
0.753 0.247 0.000
S01.7 Multiple open wounds of head
0.753 0.247 0.000
A41.8 Other specified septicaemia
0.752 0.248 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.752 0.248 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.752 0.248 0.000
F80-F89 Disorders of psychological development
0.751 0.249 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.750 0.250 0.000
E40-E46 Malnutrition
0.749 0.250 0.000
S09 Other and unspecified injuries of head
0.748 0.252 0.000
Z75.3 Unavailability and inaccessibility of health-care facilities
0.747 0.253 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.747 0.253 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.746 0.254 0.000
Z64 Problems related to certain psychosocial circumstances
0.746 0.254 0.000
X62.9 Unspecified place
0.746 0.254 0.000
X78 Intentional self-harm by sharp object
0.746 0.254 0.000
V40-V49 Car occupant injured in transport accident
0.744 0.256 0.000
Z75.4 Unavailability and inaccessibility of other helping agencies
0.742 0.258 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.742 0.258 0.000
M25.77 Osteophyte (Ankle and foot)
0.741 0.259 0.000
Q60-Q64 Congenital malformations of the urinary system
0.739 0.261 0.000
Y00-Y09 Assault
0.739 0.261 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.739 0.261 0.000
H72 Perforation of tympanic membrane
0.739 0.261 0.000
Z45.2 Adjustment and management of vascular access device
0.738 0.262 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.737 0.263 0.000
W50-W64 Exposure to animate mechanical forces
0.737 0.263 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.737 0.263 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.737 0.263 0.000
S22.0 Fracture of thoracic vertebra
0.736 0.264 0.000
M25.8 Other specified joint disorders
0.734 0.265 0.000
X50-X57 Overexertion, travel and privation
0.734 0.266 0.000
M21.0 Valgus deformity, not elsewhere classified
0.734 0.266 0.000
Z94 Transplanted organ and tissue status
0.733 0.267 0.000
F30-F39 Mood [affective] disorders
0.731 0.269 0.000
S00 Superficial injury of head
0.730 0.270 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.729 0.271 0.000
Z76 Persons encountering health services in other circumstances
0.728 0.271 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.728 0.272 0.000
M60-M63 Disorders of muscles
0.727 0.273 0.000
X20-X29 Contact with venomous animals and plants
0.726 0.274 0.000
Z60.2 Living alone
0.726 0.274 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.726 0.274 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.725 0.274 0.000
Q00-Q07 Congenital malformations of the nervous system
0.724 0.276 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.724 0.276 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.722 0.278 0.000
V20-V29 Motorcycle rider injured in transport accident
0.722 0.278 0.000
F11 Mental and behavioural disorders due to use of opioids
0.722 0.278 0.000
Z57.2 Occupational exposure to dust
0.722 0.278 0.000
F99-F99 Unspecified mental disorder
0.721 0.279 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.721 0.279 0.000
Z93.1 Gastrostomy status
0.720 0.280 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.720 0.280 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.719 0.281 0.000
Z48 Other surgical follow-up care
0.718 0.282 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.718 0.282 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
H66.9 Otitis media, unspecified
0.716 0.284 0.000
B99-B99 Other infectious diseases
0.716 0.284 0.000
S22.1 Multiple fractures of thoracic spine
0.716 0.284 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.715 0.285 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.285 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.715 0.285 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.715 0.285 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.715 0.285 0.000
T36 Poisoning by systemic antibiotics
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.714 0.286 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.714 0.286 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.713 0.287 0.000
M33 Dermatopolymyositis
0.713 0.287 0.000
M32 Systemic lupus erythematosus
0.713 0.287 0.000
M30 Polyarteritis nodosa and related conditions
0.713 0.287 0.000
M21.1 Varus deformity, not elsewhere classified
0.711 0.289 0.000
Z75.8 Other problems related to medical facilities and other health care
0.710 0.290 0.000
Z75.5 Holiday relief care
0.709 0.291 0.000
Z73 Problems related to life-management difficulty
0.708 0.292 0.000
S08 Traumatic amputation of part of head
0.708 0.292 0.000
S07 Crushing injury of head
0.708 0.292 0.000
S04 Injury of cranial nerves
0.708 0.292 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.708 0.292 0.000
S01.4 Open wound of cheek and temporomandibular area
0.708 0.292 0.000
I69.3 Sequelae of cerebral infarction
0.706 0.294 0.000
T46.1 Calcium-channel blockers
0.704 0.295 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.704 0.296 0.000
Z95.1 Presence of aortocoronary bypass graft
0.704 0.296 0.000
A49 Bacterial infection of unspecified site
0.704 0.296 0.000
S51 Open wound of forearm
0.703 0.297 0.000
E55 Vitamin D deficiency
0.703 0.297 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.703 0.297 0.000
F70-F79 Mental retardation
0.703 0.297 0.000
M80.8 Other osteoporosis with pathological fracture
0.701 0.298 0.000
M81 Osteoporosis without pathological fracture
0.701 0.299 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.697 0.303 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.697 0.303 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.697 0.303 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.697 0.303 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.697 0.303 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.697 0.303 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.697 0.303 0.000
Y45.8 Other analgesics and antipyretics
0.697 0.303 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.697 0.303 0.000
Q24 Other congenital malformations of heart
0.696 0.304 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.695 0.305 0.000
S26 Injury of heart
0.695 0.305 0.000
S25 Injury of blood vessels of thorax
0.695 0.305 0.000
S24 Injury of nerves and spinal cord at thorax level
0.695 0.305 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.695 0.305 0.000
S21 Open wound of thorax
0.695 0.305 0.000
B91 Sequelae of poliomyelitis
0.694 0.306 0.000
M54.5 Low back pain
0.694 0.306 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.693 0.307 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.692 0.308 0.000
T40.8 Lysergide [LSD]
0.692 0.308 0.000
T40.7 Cannabis (derivatives)
0.692 0.308 0.000
T40.6 Other and unspecified narcotics
0.692 0.308 0.000
T40.5 Cocaine
0.692 0.308 0.000
T40.3 Methadone
0.692 0.308 0.000
T40.1 Heroin
0.692 0.308 0.000
T40.0 Opium
0.692 0.308 0.000
M82 Osteoporosis in diseases classified elsewhere
0.692 0.308 0.000
S20 Superficial injury of thorax
0.691 0.308 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.691 0.309 0.000
S06.5 Traumatic subdural haemorrhage
0.691 0.309 0.000
S29 Other and unspecified injuries of thorax
0.691 0.309 0.000
I74.5 Embolism and thrombosis of iliac artery
0.689 0.310 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.689 0.311 0.000
F10.9 Unspecified mental and behavioural disorder
0.689 0.311 0.000
F10.8 Other mental and behavioural disorders
0.689 0.311 0.000
F10.7 Residual and late-onset psychotic disorder
0.689 0.311 0.000
F10.6 Amnesic syndrome
0.689 0.311 0.000
F10.5 Psychotic disorder
0.689 0.311 0.000
H53-H54 Visual disturbances and blindness
0.689 0.311 0.000
F20 Schizophrenia
0.689 0.311 0.000
Y83.3 Surgical operation with formation of external stoma
0.687 0.313 0.000
I00-I02 Acute rheumatic fever
0.686 0.314 0.000
H66.3 Other chronic suppurative otitis media
0.686 0.314 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.686 0.314 0.000
S06.8 Other intracranial injuries
0.685 0.315 0.000
Chapter XXII Codes for special purposes
0.685 0.315 0.000
E83 Disorders of mineral metabolism
0.684 0.316 0.000
M85 Other disorders of bone density and structure
0.684 0.316 0.000
M25.3 Other instability of joint
0.683 0.317 0.000
A40 Streptococcal septicaemia
0.683 0.317 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.683 0.317 0.000
M54.3 Sciatica
0.683 0.317 0.000
S22.9 Fracture of bony thorax, part unspecified
0.683 0.317 0.000
S22.8 Fracture of other parts of bony thorax
0.683 0.317 0.000
S22.5 Flail chest
0.683 0.317 0.000
M00-M03 Infectious arthropathies
0.682 0.317 0.000
Z58 Problems related to physical environment
0.682 0.318 0.000
M20 Acquired deformities of fingers and toes
0.681 0.319 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.681 0.319 0.000
Z94.0 Kidney transplant status
0.679 0.321 0.000
M65-M68 Disorders of synovium and tendon
0.679 0.321 0.000
M40-M43 Deforming dorsopathies
0.678 0.321 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.678 0.322 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.678 0.322 0.000
M35.5 Multifocal fibrosclerosis
0.678 0.322 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.678 0.322 0.000
M35.2 Behcet's disease
0.678 0.322 0.000
M35.1 Other overlap syndromes
0.678 0.322 0.000
Z65 Problems related to other psychosocial circumstances
0.677 0.323 0.000
Z62 Other problems related to upbringing
0.677 0.323 0.000
Z61 Problems related to negative life events in childhood
0.677 0.323 0.000
Z59 Problems related to housing and economic circumstances
0.677 0.323 0.000
Z56 Problems related to employment and unemployment
0.677 0.323 0.000
Z55 Problems related to education and literacy
0.677 0.323 0.000
W05 Fall involving wheelchair
0.677 0.323 0.000
Z75.2 Other waiting period for investigation and treatment
0.677 0.323 0.000
Z71.7 Human immunodeficiency virus [HIV] counselling
0.677 0.323 0.000
Z71.6 Tobacco abuse counselling
0.677 0.323 0.000
Z71.5 Drug abuse counselling and surveillance
0.677 0.323 0.000
Z71.2 Person consulting for explanation of investigation findings
0.677 0.323 0.000
Z71.0 Person consulting on behalf of another person
0.677 0.323 0.000
I10-I15 Hypertensive diseases
0.676 0.324 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.676 0.324 0.000
M35.7 Hypermobility syndrome
0.673 0.326 0.000
F33 Recurrent depressive disorder
0.673 0.327 0.000
M94 Other disorders of cartilage
0.672 0.328 0.000
Y45.1 Salicylates
0.672 0.328 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.672 0.328 0.000
M13.93 Arthritis, unspecified (Forearm)
0.672 0.328 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.672 0.328 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.672 0.328 0.000
M21.4 Flat foot [pes planus] (acquired)
0.671 0.329 0.000
Z89 Acquired absence of limb
0.670 0.329 0.000
Z63.4 Disappearance and death of family member
0.670 0.330 0.000
M83 Adult osteomalacia
0.670 0.330 0.000
S01.5 Open wound of lip and oral cavity
0.670 0.330 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.670 0.330 0.000
S40-S49 Injuries to the shoulder and upper arm
0.670 0.330 0.000
S64 Injury of nerves at wrist and hand level
0.670 0.330 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.669 0.330 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.669 0.330 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.669 0.330 0.000
T42.3 Barbiturates
0.669 0.330 0.000
T42.2 Succinimides and oxazolidinediones
0.669 0.330 0.000
T42.1 Iminostilbenes
0.669 0.330 0.000
T42.0 Hydantoin derivatives
0.669 0.330 0.000
M54.59 Low back pain (Site unspecified)
0.670 0.330 0.000
E20-E35 Disorders of other endocrine glands
0.668 0.332 0.000
H72.0 Central perforation of tympanic membrane
0.668 0.332 0.000
S22.31 Fracture of rib (open)
0.668 0.332 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.668 0.332 0.000
I72 Other aneurysm
0.668 0.332 0.000
H55-H59 Other disorders of eye and adnexa
0.666 0.334 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.666 0.334 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.666 0.334 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.666 0.334 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.666 0.334 0.000
Z93.3 Colostomy status
0.666 0.334 0.000
Z74 Problems related to care-provider dependency
0.665 0.335 0.000
E61 Deficiency of other nutrient elements
0.664 0.336 0.000
S01.3 Open wound of ear
0.664 0.336 0.000
S30.1 Contusion of abdominal wall
0.664 0.336 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.663 0.337 0.000
M14 Arthropathies in other diseases classified elsewhere
0.663 0.337 0.000
M12 Other specific arthropathies
0.663 0.337 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.663 0.337 0.000
M08 Juvenile arthritis
0.663 0.337 0.000
S06.4 Epidural haemorrhage
0.663 0.337 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.662 0.338 0.000
S22.20 Fracture of sternum (closed)
0.662 0.338 0.000
F60-F69 Disorders of adult personality and behaviour
0.661 0.339 0.000
Y52 Agents primarily affecting the cardiovascular system
0.661 0.339 0.000
M84 Disorders of continuity of bone
0.660 0.340 0.000
T87 Complications peculiar to reattachment and amputation
0.660 0.340 0.000
S05.1 Contusion of eyeball and orbital tissues
0.660 0.340 0.000
S01.0 Open wound of scalp
0.660 0.340 0.000
Q50-Q56 Congenital malformations of genital organs
0.659 0.340 0.000
Y43 Primarily systemic agents
0.659 0.341 0.000
S05.9 Injury of eye and orbit, part unspecified
0.659 0.341 0.000
H54 Blindness and low vision
0.659 0.341 0.000
I73.8 Other specified peripheral vascular diseases
0.659 0.341 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.659 0.341 0.000
Y83.0 Surgical operation with transplant of whole organ
0.659 0.341 0.000
W06 Fall involving bed
0.658 0.342 0.000
Z71.1 Person with feared complaint in whom no diagnosis is made
0.658 0.342 0.000
M24.2 Disorder of ligament
0.657 0.343 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.657 0.343 0.000
Y60.0 During surgical operation
0.656 0.344 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.656 0.344 0.000
Q35-Q37 Cleft lip and cleft palate
0.656 0.344 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.656 0.344 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.656 0.344 0.000
S06.9 Intracranial injury, unspecified
0.656 0.344 0.000
Y59 Other and unspecified vaccines and biological substances
0.656 0.344 0.000
Y58 Bacterial vaccines
0.656 0.344 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.656 0.344 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.656 0.344 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.656 0.344 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.656 0.344 0.000
Y48 Anaesthetics and therapeutic gases
0.656 0.344 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.656 0.344 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.656 0.344 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.656 0.344 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.656 0.344 0.000
S01.8 Open wound of other parts of head
0.655 0.344 0.000
I08 Multiple valve diseases
0.655 0.345 0.000
X84 Intentional self-harm by unspecified means
0.653 0.347 0.000
X83 Intentional self-harm by other specified means
0.653 0.347 0.000
X82 Intentional self-harm by crashing of motor vehicle
0.653 0.347 0.000
X81 Intentional self-harm by jumping or lying before moving object
0.653 0.347 0.000
X80 Intentional self-harm by jumping from a high place
0.653 0.347 0.000
X79 Intentional self-harm by blunt object
0.653 0.347 0.000
X77 Intentional self-harm by steam, hot vapours and hot objects
0.653 0.347 0.000
X76 Intentional self-harm by smoke, fire and flames
0.653 0.347 0.000
X75 Intentional self-harm by explosive material
0.653 0.347 0.000
X74 Intentional self-harm by other and unspecified firearm discharge
0.653 0.347 0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge
0.653 0.347 0.000
X72 Intentional self-harm by handgun discharge
0.653 0.347 0.000
X71 Intentional self-harm by drowning and submersion
0.653 0.347 0.000
X70 Intentional self-harm by hanging, strangulation and suffocation
0.653 0.347 0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
0.653 0.347 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.653 0.347 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.653 0.347 0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.653 0.347 0.000
X65 Intentional self-poisoning by and exposure to alcohol
0.653 0.347 0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.653 0.347 0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.653 0.347 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.653 0.347 0.000
M24.9 Joint derangement, unspecified
0.653 0.347 0.000
M24.7 Protrusio acetabuli
0.653 0.347 0.000
M24.6 Ankylosis of joint
0.653 0.347 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.653 0.347 0.000
S70-S79 Injuries to the hip and thigh
0.653 0.347 0.000
M25.2 Flail joint
0.652 0.347 0.000
M25.1 Fistula of joint
0.652 0.347 0.000
M25.0 Haemarthrosis
0.652 0.347 0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.651 0.349 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.650 0.350 0.000
W08 Fall involving other furniture
0.648 0.352 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.648 0.352 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.648 0.352 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.647 0.353 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.647 0.353 0.000
M25.5 Pain in joint
0.647 0.353 0.000
M13.8 Other specified arthritis
0.646 0.354 0.000
M13.1 Monoarthritis, not elsewhere classified
0.646 0.354 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.644 0.356 0.000
M86-M90 Other osteopathies
0.644 0.356 0.000
M24.5 Contracture of joint
0.643 0.357 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.643 0.357 0.000
S06.0 Concussion
0.642 0.358 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.642 0.358 0.000
W44 Foreign body entering into or through eye or natural orifice
0.642 0.358 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.641 0.359 0.000
M13.0 Polyarthritis, unspecified
0.641 0.359 0.000
T82.3 Mechanical complication of other vascular grafts
0.641 0.359 0.000
M20.5 Other deformities of toe(s) (acquired)
0.640 0.360 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.639 0.361 0.000
S00.9 Superficial injury of head, part unspecified
0.639 0.361 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.639 0.361 0.000
D70 Agranulocytosis
0.639 0.361 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.638 0.362 0.000
Z75.9 Unspecified problem related to medical facilities and other health care
0.638 0.362 0.000
Z75.0 Medical services not available in home
0.638 0.362 0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)
0.638 0.362 0.000
Z71.9 Counselling, unspecified
0.638 0.362 0.000
M25.9 Joint disorder, unspecified
0.637 0.363 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.637 0.363 0.000
Y83.9 Surgical procedure, unspecified
0.637 0.363 0.000
E83.1 Disorders of iron metabolism
0.637 0.363 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.636 0.364 0.000
B50-B64 Protozoal diseases
0.636 0.364 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.636 0.364 0.000
A75-A79 Rickettsioses
0.636 0.364 0.000
A70-A74 Other diseases caused by chlamydiae
0.636 0.364 0.000
A65-A69 Other spirochaetal diseases
0.636 0.364 0.000
A20-A28 Certain zoonotic bacterial diseases
0.636 0.364 0.000
A15-A19 Tuberculosis
0.636 0.364 0.000
H71 Cholesteatoma of middle ear
0.636 0.364 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.636 0.364 0.000
W21 Striking against or struck by sports equipment
0.636 0.364 0.000
T93 Sequelae of injuries of lower limb
0.636 0.364 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.635 0.365 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.634 0.366 0.000
W18 Other fall on same level
0.634 0.366 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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