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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10411619
log Bayes Factor = 0.26895
Chromosome 19   position 12,752,425  (GRCh37) Explore rs10411619 on Ensembl!
Variant rs10411619 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
0.000 0.567 0.433
I20 Angina pectoris
0.000 0.575 0.425
I21 Acute myocardial infarction
0.000 0.575 0.425
I20.0 Unstable angina
0.000 0.579 0.421
I21.9 Acute myocardial infarction, unspecified
0.000 0.594 0.406
Chapter IX Diseases of the circulatory system
0.000 0.602 0.398
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.608 0.392
I25 Chronic ischaemic heart disease
0.000 0.614 0.386
I73 Other peripheral vascular diseases
0.000 0.615 0.385
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.622 0.378
I73.9 Peripheral vascular disease, unspecified
0.000 0.625 0.375
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.627 0.373
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.628 0.372
I84 Haemorrhoids
0.000 0.630 0.370
I84.9 Unspecified haemorrhoids without complication
0.000 0.635 0.365
I25.1 Atherosclerotic heart disease
0.000 0.637 0.363
I84.8 Unspecified haemorrhoids with other complications
0.000 0.653 0.347
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.660 0.340
I77 Other disorders of arteries and arterioles
0.000 0.673 0.327
I73.0 Raynaud's syndrome
0.000 0.676 0.324
I83 Varicose veins of lower extremities
0.000 0.680 0.320
I20.8 Other forms of angina pectoris
0.000 0.684 0.316
I23 Certain current complications following acute myocardial infarction
0.000 0.690 0.310
I22 Subsequent myocardial infarction
0.000 0.690 0.310
I20.1 Angina pectoris with documented spasm
0.000 0.695 0.305
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.695 0.305
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.695 0.305
I24 Other acute ischaemic heart diseases
0.000 0.696 0.304
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.705 0.295
I77.1 Stricture of artery
0.000 0.707 0.292
I78 Diseases of capillaries
0.000 0.711 0.289
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.711 0.289
I60-I69 Cerebrovascular diseases
0.000 0.712 0.288
I00-I02 Acute rheumatic fever
0.000 0.714 0.285
I74 Arterial embolism and thrombosis
0.000 0.716 0.284
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.719 0.281
I72 Other aneurysm
0.000 0.719 0.281
I70 Atherosclerosis
0.000 0.719 0.281
I20.9 Angina pectoris, unspecified
0.000 0.719 0.281
I25.6 Silent myocardial ischaemia
0.000 0.723 0.276
I25.5 Ischaemic cardiomyopathy
0.000 0.723 0.276
I25.4 Coronary artery aneurysm
0.000 0.723 0.276
I25.3 Aneurysm of heart
0.000 0.723 0.276
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.723 0.276
I73.8 Other specified peripheral vascular diseases
0.000 0.724 0.276
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.724 0.276
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.726 0.274
I30-I52 Other forms of heart disease
0.000 0.727 0.273
I88 Nonspecific lymphadenitis
0.000 0.728 0.271
I87 Other disorders of veins
0.000 0.728 0.271
I86 Varicose veins of other sites
0.000 0.728 0.271
I85 Oesophageal varices
0.000 0.728 0.271
I82 Other venous embolism and thrombosis
0.000 0.728 0.271
I81 Portal vein thrombosis
0.000 0.728 0.271
I84.1 Internal haemorrhoids with other complications
0.000 0.731 0.269
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.734 0.265
I84.7 Unspecified thrombosed haemorrhoids
0.000 0.735 0.265
I84.4 External haemorrhoids with other complications
0.000 0.735 0.265
I84.0 Internal thrombosed haemorrhoids
0.000 0.735 0.265
I21.4 Acute subendocardial myocardial infarction
0.000 0.746 0.254
I25.2 Old myocardial infarction
0.000 0.749 0.251
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.756 0.244
I71 Aortic aneurysm and dissection
0.000 0.756 0.243
I26 Pulmonary embolism
0.000 0.764 0.236
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.765 0.235
I77.8 Other specified disorders of arteries and arterioles
0.000 0.765 0.235
I77.5 Necrosis of artery
0.000 0.765 0.235
I77.4 Coeliac artery compression syndrome
0.000 0.765 0.235
I77.3 Arterial fibromuscular dysplasia
0.000 0.765 0.235
I77.2 Rupture of artery
0.000 0.765 0.235
I77.0 Arteriovenous fistula, acquired
0.000 0.765 0.235
I05-I09 Chronic rheumatic heart diseases
0.000 0.766 0.233
I51 Complications and ill-defined descriptions of heart disease
0.000 0.770 0.230
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.770 0.230
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.770 0.230
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.772 0.228
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.774 0.226
I84.3 External thrombosed haemorrhoids
0.000 0.774 0.225
I50 Heart failure
0.000 0.777 0.223
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.777 0.222
I22.8 Subsequent myocardial infarction of other sites
0.000 0.777 0.222
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.777 0.222
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.777 0.222
I23.8 Other current complications following acute myocardial infarction
0.000 0.777 0.222
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.777 0.222
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.777 0.222
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.777 0.222
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.777 0.222
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.777 0.222
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.777 0.222
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.777 0.222
I47 Paroxysmal tachycardia
0.000 0.779 0.221
I63 Cerebral infarction
0.000 0.780 0.220
I24.1 Dressler's syndrome
0.000 0.782 0.218
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.782 0.218
I84.5 External haemorrhoids without complication
0.000 0.782 0.218
I84.6 Residual haemorrhoidal skin tags
0.000 0.784 0.216
I78.1 Naevus, nonneoplastic
0.000 0.785 0.215
I28 Other diseases of pulmonary vessels
0.000 0.788 0.211
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.789 0.211
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.793 0.207
I78.9 Disease of capillaries, unspecified
0.000 0.793 0.207
I78.8 Other diseases of capillaries
0.000 0.793 0.207
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.793 0.207
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.793 0.206
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.793 0.206
I62 Other nontraumatic intracranial haemorrhage
0.000 0.793 0.206
I77.6 Arteritis, unspecified
0.000 0.795 0.205
I02 Rheumatic chorea
0.000 0.795 0.205
I01 Rheumatic fever with heart involvement
0.000 0.795 0.205
I00 Rheumatic fever without mention of heart involvement
0.000 0.795 0.205
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.796 0.204
I74.8 Embolism and thrombosis of other arteries
0.000 0.796 0.204
I74.5 Embolism and thrombosis of iliac artery
0.000 0.796 0.204
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.796 0.204
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.796 0.204
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.796 0.204
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.796 0.204
I34 Nonrheumatic mitral valve disorders
0.000 0.796 0.204
I24.8 Other forms of acute ischaemic heart disease
0.000 0.797 0.203
I60 Subarachnoid haemorrhage
0.000 0.798 0.202
I70.9 Generalised and unspecified atherosclerosis
0.000 0.798 0.201
I70.8 Atherosclerosis of other arteries
0.000 0.798 0.201
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.798 0.201
I70.1 Atherosclerosis of renal artery
0.000 0.798 0.201
I70.0 Atherosclerosis of aorta
0.000 0.798 0.201
I72.9 Aneurysm of unspecified site
0.000 0.798 0.201
I72.8 Aneurysm of other specified arteries
0.000 0.798 0.201
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.798 0.201
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.798 0.201
I72.4 Aneurysm of artery of lower extremity
0.000 0.798 0.201
I72.3 Aneurysm of iliac artery
0.000 0.798 0.201
I72.2 Aneurysm of renal artery
0.000 0.798 0.201
I72.1 Aneurysm of artery of upper extremity
0.000 0.798 0.201
I72.0 Aneurysm of carotid artery
0.000 0.798 0.201
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.798 0.201
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.798 0.201
I79.1 Aortitis in diseases classified elsewhere
0.000 0.798 0.201
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.798 0.201
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.799 0.201
I35 Nonrheumatic aortic valve disorders
0.000 0.801 0.199
I47.2 Ventricular tachycardia
0.000 0.802 0.198
I69 Sequelae of cerebrovascular disease
0.000 0.803 0.197
I84.2 Internal haemorrhoids without complication
0.000 0.804 0.196
I52 Other heart disorders in diseases classified elsewhere
0.000 0.804 0.196
I48 Atrial fibrillation and flutter
0.000 0.804 0.196
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.804 0.196
I41 Myocarditis in diseases classified elsewhere
0.000 0.804 0.196
I40 Acute myocarditis
0.000 0.804 0.196
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.804 0.196
I37 Pulmonary valve disorders
0.000 0.804 0.196
I36 Nonrheumatic tricuspid valve disorders
0.000 0.804 0.196
I33 Acute and subacute endocarditis
0.000 0.804 0.196
I32 Pericarditis in diseases classified elsewhere
0.000 0.804 0.196
I30 Acute pericarditis
0.000 0.804 0.196
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.805 0.195
I82.8 Embolism and thrombosis of other specified veins
0.000 0.805 0.195
I82.3 Embolism and thrombosis of renal vein
0.000 0.805 0.195
I82.2 Embolism and thrombosis of vena cava
0.000 0.805 0.195
I82.1 Thrombophlebitis migrans
0.000 0.805 0.195
I82.0 Budd-Chiari syndrome
0.000 0.805 0.195
I85.9 Oesophageal varices without bleeding
0.000 0.805 0.195
I85.0 Oesophageal varices with bleeding
0.000 0.805 0.195
I86.8 Varicose veins of other specified sites
0.000 0.805 0.195
I86.4 Gastric varices
0.000 0.805 0.195
I86.3 Vulval varices
0.000 0.805 0.195
I86.2 Pelvic varices
0.000 0.805 0.195
I86.1 Scrotal varices
0.000 0.805 0.195
I86.0 Sublingual varices
0.000 0.805 0.195
I87.9 Disorder of vein, unspecified
0.000 0.805 0.195
I87.8 Other specified disorders of veins
0.000 0.805 0.195
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.805 0.195
I87.1 Compression of vein
0.000 0.805 0.195
I87.0 Postphlebitic syndrome
0.000 0.805 0.195
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.805 0.195
I88.8 Other nonspecific lymphadenitis
0.000 0.805 0.195
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.805 0.195
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.805 0.195
I51.8 Other ill-defined heart diseases
0.000 0.805 0.195
I38 Endocarditis, valve unspecified
0.000 0.805 0.195
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.807 0.193
I27 Other pulmonary heart diseases
0.000 0.809 0.190
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.809 0.190
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.809 0.190
I89.1 Lymphangitis
0.000 0.809 0.190
I50.1 Left ventricular failure
0.000 0.810 0.190
I89.0 Lymphoedema, not elsewhere classified
0.000 0.815 0.184
I51.9 Heart disease, unspecified
0.000 0.816 0.184
I42 Cardiomyopathy
0.000 0.818 0.182
I49 Other cardiac arrhythmias
0.000 0.819 0.181
I63.9 Cerebral infarction, unspecified
0.000 0.820 0.180
I67 Other cerebrovascular diseases
0.000 0.822 0.178
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.825 0.175
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.825 0.175
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.825 0.175
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.825 0.175
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.825 0.175
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.825 0.175
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.825 0.175
I71.0 Dissection of aorta [any part]
0.000 0.825 0.175
I44 Atrioventricular and left bundle-branch block
0.000 0.826 0.174
I35.0 Aortic (valve) stenosis
0.000 0.828 0.172
I61 Intracerebral haemorrhage
0.000 0.829 0.171
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.831 0.169
I09 Other rheumatic heart diseases
0.000 0.832 0.167
I06 Rheumatic aortic valve diseases
0.000 0.832 0.167
I05 Rheumatic mitral valve diseases
0.000 0.832 0.167
I46 Cardiac arrest
0.000 0.834 0.166
I51.6 Cardiovascular disease, unspecified
0.000 0.835 0.165
I51.5 Myocardial degeneration
0.000 0.835 0.165
I51.4 Myocarditis, unspecified
0.000 0.835 0.165
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.835 0.165
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.835 0.165
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.835 0.165
I51.0 Cardiac septal defect, acquired
0.000 0.835 0.165
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.837 0.163
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.837 0.163
I99 Other and unspecified disorders of circulatory system
0.000 0.837 0.163
I50.9 Heart failure, unspecified
0.000 0.838 0.162
I31 Other diseases of pericardium
0.000 0.841 0.158
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.842 0.158
I47.0 Reentry ventricular arrhythmia
0.000 0.842 0.158
I63.8 Other cerebral infarction
0.000 0.842 0.158
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.842 0.158
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.842 0.158
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.842 0.158
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.842 0.158
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.842 0.158
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.842 0.158
I65.2 Occlusion and stenosis of carotid artery
0.000 0.843 0.156
I45 Other conduction disorders
0.000 0.844 0.156
I34.1 Mitral (valve) prolapse
0.000 0.846 0.154
I07 Rheumatic tricuspid valve diseases
0.000 0.847 0.153
I51.7 Cardiomegaly
0.000 0.847 0.153
I50.0 Congestive heart failure
0.000 0.848 0.152
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.848 0.152
I28.8 Other specified diseases of pulmonary vessels
0.000 0.848 0.152
I28.1 Aneurysm of pulmonary artery
0.000 0.848 0.152
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.848 0.152
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.848 0.152
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.848 0.152
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.848 0.152
I65.1 Occlusion and stenosis of basilar artery
0.000 0.848 0.152
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.848 0.152
I10-I15 Hypertensive diseases
0.000 0.851 0.149
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.852 0.148
I62.1 Nontraumatic extradural haemorrhage
0.000 0.852 0.148
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.852 0.148
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.852 0.148
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.852 0.148
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.852 0.148
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.852 0.148
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.852 0.148
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.852 0.148
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.852 0.148
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.852 0.148
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.852 0.148
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.852 0.148
I68.0 Cerebral amyloid angiopathy
0.000 0.852 0.148
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.853 0.147
I01.8 Other acute rheumatic heart disease
0.000 0.853 0.147
I01.2 Acute rheumatic myocarditis
0.000 0.853 0.147
I01.1 Acute rheumatic endocarditis
0.000 0.853 0.147
I01.0 Acute rheumatic pericarditis
0.000 0.853 0.147
I02.9 Rheumatic chorea without heart involvement
0.000 0.853 0.147
I02.0 Rheumatic chorea with heart involvement
0.000 0.853 0.147
I34.0 Mitral (valve) insufficiency
0.000 0.853 0.147
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.853 0.146
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.854 0.146
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.854 0.146
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.854 0.146
I60.8 Other subarachnoid haemorrhage
0.000 0.855 0.145
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.855 0.145
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.855 0.145
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.855 0.145
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.855 0.145
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.855 0.145
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.855 0.145
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.855 0.145
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.855 0.145
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.855 0.144
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.855 0.144
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.855 0.144
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.855 0.144
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.855 0.144
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.855 0.144
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.855 0.144
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.855 0.144
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.855 0.144
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.855 0.144
I67.8 Other specified cerebrovascular diseases
0.000 0.857 0.143
I35.8 Other aortic valve disorders
0.000 0.857 0.143
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.857 0.143
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.859 0.141
I69.3 Sequelae of cerebral infarction
0.000 0.859 0.141
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.859 0.141
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.859 0.141
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.859 0.141
I30.9 Acute pericarditis, unspecified
0.000 0.859 0.140
I30.8 Other forms of acute pericarditis
0.000 0.859 0.140
I30.1 Infective pericarditis
0.000 0.859 0.140
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.859 0.140
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.859 0.140
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.859 0.140
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.859 0.140
I33.9 Acute endocarditis, unspecified
0.000 0.859 0.140
I33.0 Acute and subacute infective endocarditis
0.000 0.859 0.140
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.859 0.140
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.859 0.140
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.859 0.140
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.859 0.140
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.859 0.140
I37.9 Pulmonary valve disorder, unspecified
0.000 0.859 0.140
I37.8 Other pulmonary valve disorders
0.000 0.859 0.140
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.859 0.140
I37.1 Pulmonary valve insufficiency
0.000 0.859 0.140
I37.0 Pulmonary valve stenosis
0.000 0.859 0.140
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.859 0.140
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.859 0.140
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.859 0.140
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.859 0.140
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.859 0.140
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.859 0.140
I40.9 Acute myocarditis, unspecified
0.000 0.859 0.140
I40.8 Other acute myocarditis
0.000 0.859 0.140
I40.1 Isolated myocarditis
0.000 0.859 0.140
I40.0 Infective myocarditis
0.000 0.859 0.140
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.859 0.140
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.859 0.140
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.859 0.140
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.859 0.140
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.859 0.140
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.859 0.140
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.859 0.140
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.859 0.140
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.859 0.140
I48.4 Atypical atrial flutter
0.000 0.859 0.140
I48.3 Typical atrial flutter
0.000 0.859 0.140
I48.2 Chronic atrial fibrillation
0.000 0.859 0.140
I48.1 Persistent atrial fibrillation
0.000 0.859 0.140
I48.0 Paroxysmal atrial fibrillation
0.000 0.859 0.140
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.859 0.140
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.859 0.140
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.859 0.140
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.860 0.140
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.863 0.137
I08 Multiple valve diseases
0.000 0.863 0.137
I27.9 Pulmonary heart disease, unspecified
0.000 0.863 0.137
I27.8 Other specified pulmonary heart diseases
0.000 0.863 0.137
I27.1 Kyphoscoliotic heart disease
0.000 0.863 0.137
I42.9 Cardiomyopathy, unspecified
0.000 0.864 0.135
I44.0 Atrioventricular block, first degree
0.000 0.866 0.134
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.868 0.132
I42.8 Other cardiomyopathies
0.000 0.869 0.131
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.869 0.131
I42.6 Alcoholic cardiomyopathy
0.000 0.869 0.131
I42.5 Other restrictive cardiomyopathy
0.000 0.869 0.131
I42.4 Endocardial fibroelastosis
0.000 0.869 0.131
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.869 0.131
I42.2 Other hypertrophic cardiomyopathy
0.000 0.869 0.131
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.869 0.131
I27.2 Other secondary pulmonary hypertension
0.000 0.870 0.130
I49.4 Other and unspecified premature depolarisation
0.000 0.870 0.130
I49.3 Ventricular premature depolarisation
0.000 0.870 0.130
I49.2 Junctional premature depolarisation
0.000 0.870 0.130
I49.1 Atrial premature depolarisation
0.000 0.870 0.130
I49.5 Sick sinus syndrome
0.000 0.870 0.130
I49.8 Other specified cardiac arrhythmias
0.000 0.870 0.130
I49.9 Cardiac arrhythmia, unspecified
0.000 0.871 0.129
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.872 0.128
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.872 0.128
I67.5 Moyamoya disease
0.000 0.872 0.128
I67.4 Hypertensive encephalopathy
0.000 0.872 0.128
I67.3 Progressive vascular leukoencephalopathy
0.000 0.872 0.128
I67.2 Cerebral atherosclerosis
0.000 0.872 0.128
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.872 0.128
I44.6 Other and unspecified fascicular block
0.000 0.875 0.125
I44.5 Left posterior fascicular block
0.000 0.875 0.125
I44.4 Left anterior fascicular block
0.000 0.875 0.125
I44.3 Other and unspecified atrioventricular block
0.000 0.875 0.125
I27.0 Primary pulmonary hypertension
0.000 0.876 0.124
I35.1 Aortic (valve) insufficiency
0.000 0.876 0.124
I61.8 Other intracerebral haemorrhage
0.000 0.877 0.122
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.877 0.122
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.877 0.122
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.877 0.122
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.877 0.122
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.877 0.122
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.877 0.122
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.877 0.122
I05.9 Mitral valve disease, unspecified
0.000 0.879 0.120
I05.8 Other mitral valve diseases
0.000 0.879 0.120
I05.2 Mitral stenosis with insufficiency
0.000 0.879 0.120
I05.1 Rheumatic mitral insufficiency
0.000 0.879 0.120
I05.0 Mitral stenosis
0.000 0.879 0.120
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.879 0.120
I06.8 Other rheumatic aortic valve diseases
0.000 0.879 0.120
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.879 0.120
I06.1 Rheumatic aortic insufficiency
0.000 0.879 0.120
I06.0 Rheumatic aortic stenosis
0.000 0.879 0.120
I09.9 Rheumatic heart disease, unspecified
0.000 0.879 0.120
I09.8 Other specified rheumatic heart diseases
0.000 0.879 0.120
I09.2 Chronic rheumatic pericarditis
0.000 0.879 0.120
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.879 0.120
I09.0 Rheumatic myocarditis
0.000 0.879 0.120
I47.1 Supraventricular tachycardia
0.000 0.880 0.120
I44.2 Atrioventricular block, complete
0.000 0.880 0.120
I46.9 Cardiac arrest, unspecified
0.000 0.881 0.119
I46.1 Sudden cardiac death, so described
0.000 0.881 0.119
I49.0 Ventricular fibrillation and flutter
0.000 0.882 0.118
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.883 0.117
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.883 0.117
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.883 0.117
I97.1 Other functional disturbances following cardiac surgery
0.000 0.883 0.117
I97.0 Postcardiotomy syndrome
0.000 0.883 0.117
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.883 0.117
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.883 0.117
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.883 0.117
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.883 0.117
I98.0 Cardiovascular syphilis
0.000 0.883 0.117
I35.9 Aortic valve disorder, unspecified
0.000 0.883 0.116
I44.7 Left bundle-branch block, unspecified
0.000 0.885 0.115
I31.8 Other specified diseases of pericardium
0.000 0.886 0.114
I31.2 Haemopericardium, not elsewhere classified
0.000 0.886 0.114
I31.1 Chronic constrictive pericarditis
0.000 0.886 0.114
I31.0 Chronic adhesive pericarditis
0.000 0.886 0.114
I45.9 Conduction disorder, unspecified
0.000 0.888 0.112
I45.8 Other specified conduction disorders
0.000 0.888 0.112
I45.5 Other specified heart block
0.000 0.888 0.112
I45.4 Nonspecific intraventricular block
0.000 0.888 0.112
I45.3 Trifascicular block
0.000 0.888 0.112
I45.2 Bifascicular block
0.000 0.888 0.112
I45.0 Right fascicular block
0.000 0.888 0.112
I42.0 Dilated cardiomyopathy
0.000 0.889 0.110
I31.3 Pericardial effusion (noninflammatory)
0.000 0.890 0.110
I07.9 Tricuspid valve disease, unspecified
0.000 0.890 0.110
I07.8 Other tricuspid valve diseases
0.000 0.890 0.110
I07.2 Tricuspid stenosis with insufficiency
0.000 0.890 0.110
I07.0 Tricuspid stenosis
0.000 0.890 0.110
I44.1 Atrioventricular block, second degree
0.000 0.892 0.108
I80 Phlebitis and thrombophlebitis
0.001 0.892 0.107
I15 Secondary hypertension
0.000 0.893 0.107
I13 Hypertensive heart and renal disease
0.000 0.893 0.107
I11 Hypertensive heart disease
0.000 0.893 0.107
I95 Hypotension
0.000 0.894 0.105
I67.1 Cerebral aneurysm, nonruptured
0.000 0.896 0.104
I67.9 Cerebrovascular disease, unspecified
0.000 0.898 0.102
I08.9 Multiple valve disease, unspecified
0.000 0.901 0.098
I08.8 Other multiple valve diseases
0.000 0.901 0.098
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.901 0.098
I45.1 Other and unspecified right bundle-branch block
0.000 0.902 0.097
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.904 0.096
I07.1 Tricuspid insufficiency
0.000 0.904 0.095
I45.6 Preexcitation syndrome
0.000 0.907 0.093
I46.0 Cardiac arrest with successful resuscitation
0.001 0.910 0.089
I08.0 Disorders of both mitral and aortic valves
0.000 0.911 0.088
I61.9 Intracerebral haemorrhage, unspecified
0.001 0.913 0.087
I12 Hypertensive renal disease
0.000 0.914 0.085
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.914 0.085
I31.9 Disease of pericardium, unspecified
0.001 0.917 0.083
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.921 0.079
I80.8 Phlebitis and thrombophlebitis of other sites
0.001 0.922 0.077
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.001 0.922 0.077
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.923 0.077
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.923 0.077
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.923 0.077
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.923 0.077
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.923 0.077
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.923 0.077
I15.9 Seconday hypertension, unspecified
0.000 0.923 0.077
I15.8 Other secondary hypertension
0.000 0.923 0.077
I15.2 Hypertension secondary to endocrine disorders
0.000 0.923 0.077
I15.1 Hypertension secondary to other renal disorders
0.000 0.923 0.077
I15.0 Renovascular hypertension
0.000 0.923 0.077
I95.8 Other hypotension
0.000 0.924 0.076
I95.2 Hypotension due to drugs
0.000 0.924 0.076
I95.0 Idiopathic hypotension
0.000 0.924 0.076
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.001 0.931 0.068
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.001 0.935 0.064
I12.9 Hypertensive renal disease without renal failure
0.000 0.938 0.061
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.001 0.939 0.060
I95.1 Orthostatic hypotension
0.000 0.943 0.057
I95.9 Hypotension, unspecified
0.000 0.948 0.051
I12.0 Hypertensive renal disease with renal failure
0.001 0.960 0.039
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.001 0.962 0.036
I10 Essential (primary) hypertension
0.000 0.969 0.031
Z95.1 Presence of aortocoronary bypass graft
0.000 0.973 0.027
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.980 0.020
Z95.0 Presence of cardiac pacemaker
0.000 0.981 0.019
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.982 0.018
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.986 0.014
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.987 0.013
Z95.3 Presence of xenogenic heart valve
0.000 0.988 0.012
Z95.4 Presence of other heart-valve replacement
0.000 0.988 0.012
Z95.2 Presence of prosthetic heart valve
0.000 0.988 0.012
Z92.2 Personal history of long-term (current) use of other medicaments
0.000 0.990 0.010
Z92.1 Personal history of long-term (current) use of anticoagulants
0.000 0.992 0.008
Z92 Personal history of medical treatment
0.000 0.993 0.007
S00.8 Superficial injury of other parts of head
0.006 0.994 0.000
Z92.9 Personal history of medical treatment, unspecified
0.000 0.994 0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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