TreeWAS – Variant ID: rs10439884

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
Chapter II Neoplasms	0.996	0.004
I30-I52 Other forms of heart disease	0.995	0.005
I60-I69 Cerebrovascular diseases	0.994	0.006
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.994	0.006
Chapter XV Pregnancy, childbirth and the puerperium	0.989	0.011
S60-S69 Injuries to the wrist and hand	0.988	0.012
C79 Secondary malignant neoplasm of other sites	0.980	0.020
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.974	0.026
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.973	0.027
I51 Complications and ill-defined descriptions of heart disease	0.972	0.028
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.972	0.028
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.968	0.032
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.952	0.048
I65.2 Occlusion and stenosis of carotid artery	0.950	0.050
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.949	0.051
I51.7 Cardiomegaly	0.949	0.051
S70-S79 Injuries to the hip and thigh	0.936	0.064
C78.7 Secondary malignant neoplasm of liver	0.934	0.066
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.928	0.072
I50 Heart failure	0.928	0.072
D70-D77 Other diseases of blood and blood-forming organs	0.923	0.077
Chapter X Diseases of the respiratory system	0.921	0.079
I34 Nonrheumatic mitral valve disorders	0.920	0.080
S61 Open wound of wrist and hand	0.915	0.085
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.913	0.087
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.912	0.088
J95-J99 Other diseases of the respiratory system	0.912	0.088
I61 Intracerebral haemorrhage	0.910	0.090
S32 Fracture of lumbar spine and pelvis	0.906	0.094
C60-C63 Malignant neoplasms of male genital organs	0.900	0.100
I38 Endocarditis, valve unspecified	0.897	0.103
O36 Maternal care for other known or suspected foetal problems	0.897	0.103
I95-I99 Other and unspecified disorders of the circulatory system	0.889	0.111
I34.0 Mitral (valve) insufficiency	0.887	0.113
D70 Agranulocytosis	0.887	0.113
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.885	0.115
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.883	0.117
I70-I79 Diseases of arteries, arterioles and capillaries	0.880	0.120
J98 Other respiratory disorders	0.879	0.121
S20-S29 Injuries to the thorax	0.879	0.121
T51 Toxic effect of alcohol	0.877	0.123
Q80-Q89 Other congenital malformations	0.875	0.125
S61.0 Open wound of finger(s) without damage to nail	0.869	0.131
Chapter XX External causes of morbidity and mortality	0.866	0.134
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.855	0.145
S66 Injury of muscle and tendon at wrist and hand level	0.854	0.146
J98.4 Other disorders of lung	0.854	0.146
C50-C50 Malignant neoplasm of breast	0.853	0.147
I50.9 Heart failure, unspecified	0.851	0.149
C79.9 Secondary malignant neoplasm, unspecified site	0.846	0.154
S50-S59 Injuries to the elbow and forearm	0.844	0.156
T51.0 Ethanol	0.839	0.161
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.839	0.161
I05-I09 Chronic rheumatic heart diseases	0.839	0.161
I50.1 Left ventricular failure	0.836	0.164
C71 Malignant neoplasm of brain	0.830	0.170
I63 Cerebral infarction	0.828	0.172
S40-S49 Injuries to the shoulder and upper arm	0.826	0.174
O20-O29 Other maternal disorders predominantly related to pregnancy	0.824	0.176
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.823	0.177
D50-D53 Nutritional anaemias	0.819	0.181
S72 Fracture of femur	0.818	0.182
J09-J18 Influenza and pneumonia	0.816	0.184
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.815	0.185
T36-T50 Poisoning by drugs, medicaments and biological substances	0.814	0.186
J99 Respiratory disorders in diseases classified elsewhere	0.814	0.186
I42 Cardiomyopathy	0.812	0.188
S64 Injury of nerves at wrist and hand level	0.811	0.189
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.806	0.194
D37-D48 Neoplasms of uncertain or unknown behaviour	0.805	0.195
I51.9 Heart disease, unspecified	0.805	0.195
T31 Burns classified according to extent of body surface involved	0.803	0.197
S62 Fracture at wrist and hand level	0.801	0.199
J80-J84 Other respiratory diseases principally affecting the interstitium	0.801	0.199
I69 Sequelae of cerebrovascular disease	0.801	0.199
C79.6 Secondary malignant neoplasm of ovary	0.800	0.200
O36.8 Maternal care for other specified foetal problems	0.799	0.201
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.794	0.206
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.794	0.206
S60 Superficial injury of wrist and hand	0.790	0.210
Q38-Q45 Other congenital malformations of the digestive system	0.787	0.212
S32.5 Fracture of pubis	0.787	0.213
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.784	0.216
I95 Hypotension	0.783	0.217
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.782	0.218
O46 Antepartum haemorrhage, not elsewhere classified	0.780	0.220
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.779	0.221
S61.7 Multiple open wounds of wrist and hand	0.777	0.223
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.777	0.223
C78.0 Secondary malignant neoplasm of lung	0.775	0.225
O36.0 Maternal care for rhesus isoimmunisation	0.775	0.225
C78.4 Secondary malignant neoplasm of small intestine	0.774	0.226
S27 Injury of other and unspecified intrathoracic organs	0.774	0.226
X60-X84 Intentional self-harm	0.772	0.228
D80-D89 Certain disorders involving the immune mechanism	0.772	0.228
C61 Malignant neoplasm of prostate	0.771	0.229
S32.0 Fracture of lumbar vertebra	0.771	0.229
T20-T25 Burns and corrosions of external body surface, specified by site	0.771	0.229
I61.9 Intracerebral haemorrhage, unspecified	0.767	0.232
O16 Unspecified maternal hypertension	0.767	0.233
S10-S19 Injuries to the neck	0.767	0.233
I67 Other cerebrovascular diseases	0.765	0.235
C62 Malignant neoplasm of testis	0.765	0.235
O43 Placental disorders	0.764	0.236
J95 Postprocedural respiratory disorders, not elsewhere classified	0.762	0.238
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.762	0.238
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.759	0.241
C79.2 Secondary malignant neoplasm of skin	0.758	0.242
D51 Vitamin B12 deficiency anaemia	0.757	0.243
O80-O84 Delivery	0.756	0.243
I60 Subarachnoid haemorrhage	0.756	0.244
Q12 Congenital lens malformations	0.755	0.245
O85-O92 Complications predominantly related to the puerperium	0.755	0.245
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.751	0.249
Q82 Other congenital malformations of skin	0.750	0.250
O35 Maternal care for known or suspected foetal abnormality and damage	0.750	0.250
C50 Malignant neoplasm of breast	0.750	0.250
I61.4 Intracerebral haemorrhage in cerebellum	0.750	0.250
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.747	0.253
Q00-Q07 Congenital malformations of the nervous system	0.746	0.254
T31.0 Burns involving less than 10% of body surface	0.744	0.256
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.743	0.257
I51.0 Cardiac septal defect, acquired	0.740	0.260
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.739	0.261
J84 Other interstitial pulmonary diseases	0.738	0.262
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.737	0.263
S70 Superficial injury of hip and thigh	0.736	0.264
I74 Arterial embolism and thrombosis	0.735	0.265
I61.8 Other intracerebral haemorrhage	0.734	0.266
S69 Other and unspecified injuries of wrist and hand	0.732	0.268
J98.0 Diseases of bronchus, not elsewhere classified	0.731	0.269
Q60-Q64 Congenital malformations of the urinary system	0.731	0.269
S40 Superficial injury of shoulder and upper arm	0.731	0.269
O23 Infections of genito-urinary tract in pregnancy	0.730	0.270
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.728	0.272
I08 Multiple valve diseases	0.727	0.273
C69 Malignant neoplasm of eye and adnexa	0.726	0.274
S32.7 Multiple fractures of lumbar spine and pelvis	0.726	0.274
I95.1 Orthostatic hypotension	0.726	0.274
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.726	0.274
J99.8 Respiratory disorders in other diseases classified elsewhere	0.725	0.275
I33 Acute and subacute endocarditis	0.724	0.275
S67 Crushing injury of wrist and hand	0.724	0.276
I70 Atherosclerosis	0.723	0.277
O48 Prolonged pregnancy	0.723	0.277
I73 Other peripheral vascular diseases	0.720	0.280
S79 Other and unspecified injuries of hip and thigh	0.720	0.280
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
T15-T19 Effects of foreign body entering through natural orifice	0.716	0.284
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.714	0.286
C40-C41 Malignant neoplasms of bone and articular cartilage	0.714	0.286
I52 Other heart disorders in diseases classified elsewhere	0.713	0.287
I48 Atrial fibrillation and flutter	0.713	0.287
I43 Cardiomyopathy in diseases classified elsewhere	0.713	0.287
I41 Myocarditis in diseases classified elsewhere	0.713	0.287
I40 Acute myocarditis	0.713	0.287
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.713	0.287
I37 Pulmonary valve disorders	0.713	0.287
I32 Pericarditis in diseases classified elsewhere	0.713	0.287
O30 Multiple gestation	0.713	0.287
I68 Cerebrovascular disorders in diseases classified elsewhere	0.713	0.287
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.713	0.287
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.713	0.287
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.712	0.288
C76 Malignant neoplasm of other and ill-defined sites	0.712	0.288
I46 Cardiac arrest	0.712	0.288
S65 Injury of blood vessels at wrist and hand level	0.708	0.292
Chapter XXII Codes for special purposes	0.708	0.292
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.707	0.292
S50 Superficial injury of forearm	0.707	0.293
O94-O99 Other obstetric conditions, not elsewhere classified	0.707	0.293
S32.3 Fracture of ilium	0.706	0.294
I42.0 Dilated cardiomyopathy	0.706	0.294
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.705	0.295
J18 Pneumonia, organism unspecified	0.705	0.295
Q20-Q28 Congenital malformations of the circulatory system	0.705	0.295
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.702	0.298
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.702	0.298
S32.50 Fracture of pubis (closed)	0.702	0.298
S71 Open wound of hip and thigh	0.700	0.300
S30 Superficial injury of abdomen, lower back and pelvis	0.699	0.301
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.698	0.302
C78.1 Secondary malignant neoplasm of mediastinum	0.698	0.302
I51.6 Cardiovascular disease, unspecified	0.697	0.303
I51.5 Myocardial degeneration	0.697	0.303
I51.4 Myocarditis, unspecified	0.697	0.303
I51.3 Intracardiac thrombosis, not elsewhere classified	0.697	0.303
I51.2 Rupture of papillary muscle, not elsewhere classified	0.697	0.303
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.697	0.303
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.697	0.303
Q35-Q37 Cleft lip and cleft palate	0.697	0.303
Q30-Q34 Congenital malformations of the respiratory system	0.697	0.303
O32 Maternal care for known or suspected malpresentation of foetus	0.697	0.303
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.697	0.303
S72.0 Fracture of neck of femur	0.696	0.304
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.696	0.304
D72 Other disorders of white blood cells	0.695	0.305
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.695	0.305
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.694	0.306
I65.8 Occlusion and stenosis of other precerebral artery	0.694	0.306
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.694	0.306
I65.1 Occlusion and stenosis of basilar artery	0.694	0.306
I65.0 Occlusion and stenosis of vertebral artery	0.694	0.306
O42 Premature rupture of membranes	0.694	0.306
Q50-Q56 Congenital malformations of genital organs	0.693	0.307
I62 Other nontraumatic intracranial haemorrhage	0.691	0.309
I36 Nonrheumatic tricuspid valve disorders	0.691	0.309
D55-D59 Haemolytic anaemias	0.688	0.312
C71.8 Overlapping lesion of brain	0.686	0.314
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.686	0.314
I95.2 Hypotension due to drugs	0.685	0.315
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.684	0.316
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.684	0.316
Q12.0 Congenital cataract	0.684	0.316
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.684	0.316
O12.0 Gestational oedema	0.683	0.317
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.682	0.317
S37 Injury of urinary and pelvic organs	0.682	0.317
S36 Injury of intra-abdominal organs	0.682	0.317
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.682	0.317
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.682	0.317
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.682	0.317
S31 Open wound of abdomen, lower back and pelvis	0.682	0.317
S29 Other and unspecified injuries of thorax	0.681	0.319
O45 Premature separation of placenta [abruptio placentae]	0.681	0.319
O44 Placenta praevia	0.681	0.319
O33 Maternal care for known or suspected disproportion	0.681	0.319
O31 Complications specific to multiple gestation	0.681	0.319
I63.8 Other cerebral infarction	0.679	0.321
S64.3 Injury of digital nerve of thumb	0.679	0.321
S72.2 Subtrochanteric fracture	0.679	0.321
O36.6 Maternal care for excessive foetal growth	0.679	0.321
I98 Other disorders of circulatory system in diseases classified elsewhere	0.678	0.321
O36.5 Maternal care for poor foetal growth	0.678	0.322
S68 Traumatic amputation of wrist and hand	0.678	0.322
D52 Folate deficiency anaemia	0.678	0.322
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.678	0.322
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.676	0.324
V10-V19 Pedal cyclist injured in transport accident	0.676	0.324
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.676	0.324
S32.00 Fracture of lumbar vertebra (closed)	0.675	0.325
S49 Other and unspecified injuries of shoulder and upper arm	0.672	0.328
C50.1 Central portion of breast	0.672	0.328
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.671	0.328
S78 Traumatic amputation of hip and thigh	0.671	0.329
S77 Crushing injury of hip and thigh	0.671	0.329
S76 Injury of muscle and tendon at hip and thigh level	0.671	0.329
S75 Injury of blood vessels at hip and thigh level	0.671	0.329
S74 Injury of nerves at hip and thigh level	0.671	0.329
O41 Other disorders of amniotic fluid and membranes	0.670	0.329
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.669	0.331
C71.3 Parietal lobe	0.669	0.331
C62.9 Testis, unspecified	0.667	0.333
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.667	0.333
Y41 Other systemic anti-infectives and antiparasitics	0.667	0.333
I47 Paroxysmal tachycardia	0.666	0.334
C71.2 Temporal lobe	0.666	0.334
T65 Toxic effect of other and unspecified substances	0.665	0.334
T63 Toxic effect of contact with venomous animals	0.665	0.334
T62 Toxic effect of other noxious substances eaten as food	0.665	0.334
T61 Toxic effect of noxious substances eaten as seafood	0.665	0.334
T60 Toxic effect of pesticides	0.665	0.334
T59 Toxic effect of other gases, fumes and vapours	0.665	0.334
T57 Toxic effect of other inorganic substances	0.665	0.334
T56 Toxic effect of metals	0.665	0.334
T54 Toxic effect of corrosive substances	0.665	0.334
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.665	0.334
T52 Toxic effect of organic solvents	0.665	0.334
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.665	0.334
T58 Toxic effect of carbon monoxide	0.665	0.334
T55 Toxic effect of soaps and detergents	0.665	0.334
T79-T79 Certain early complications of trauma	0.664	0.336
S32.1 Fracture of sacrum	0.664	0.336
I20-I25 Ischaemic heart diseases	0.664	0.336
D66 Hereditary factor VIII deficiency	0.663	0.337
C78.2 Secondary malignant neoplasm of pleura	0.662	0.338
S61.1 Open wound of finger(s) with damage to nail	0.662	0.338
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.662	0.338
D74 Methaemoglobinaemia	0.662	0.338
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.662	0.338
D71 Functional disorders of polymorphonuclear neutrophils	0.662	0.338
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.660	0.340
I34.8 Other nonrheumatic mitral valve disorders	0.660	0.340
I34.2 Nonrheumatic mitral (valve) stenosis	0.660	0.340
J18.1 Lobar pneumonia, unspecified	0.660	0.340
T46 Poisoning by agents primarily affecting the cardiovascular system	0.660	0.340
S20 Superficial injury of thorax	0.659	0.340
O46.9 Antepartum haemorrhage, unspecified	0.659	0.341
I71 Aortic aneurysm and dissection	0.658	0.342
Y52 Agents primarily affecting the cardiovascular system	0.658	0.342
T66-T78 Other and unspecified effects of external causes	0.658	0.342
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.655	0.344
V40-V49 Car occupant injured in transport accident	0.655	0.345
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.655	0.345
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.654	0.345
C70 Malignant neoplasm of meninges	0.654	0.345
J95.8 Other postprocedural respiratory disorders	0.654	0.346
O15 Eclampsia	0.654	0.346
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.654	0.346
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.654	0.346
J96 Respiratory failure, not elsewhere classified	0.654	0.346
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.654	0.346
Q18 Other congenital malformations of face and neck	0.653	0.347
I61.6 Intracerebral haemorrhage, multiple localised	0.652	0.347
I61.5 Intracerebral haemorrhage, intraventricular	0.652	0.347
I61.3 Intracerebral haemorrhage in brain stem	0.652	0.347
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.652	0.347
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.652	0.347
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.652	0.347
C71.9 Brain, unspecified	0.652	0.348
S52 Fracture of forearm	0.652	0.348
J15 Bacterial pneumonia, not elsewhere classified	0.652	0.348
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.649	0.350
S32.2 Fracture of coccyx	0.649	0.350
Q87.4 Marfan's syndrome	0.649	0.351
C73 Malignant neoplasm of thyroid gland	0.648	0.352
I44 Atrioventricular and left bundle-branch block	0.648	0.352
D75 Other diseases of blood and blood-forming organs	0.648	0.352
Y51 Drugs primarily affecting the autonomic nervous system	0.648	0.352
C79.8 Secondary malignant neoplasm of other specified sites	0.648	0.352
V20-V29 Motorcycle rider injured in transport accident	0.648	0.352
I67.8 Other specified cerebrovascular diseases	0.646	0.353
C63 Malignant neoplasm of other and unspecified male genital organs	0.645	0.354
C60 Malignant neoplasm of penis	0.645	0.354
S60.8 Other superficial injuries of wrist and hand	0.645	0.355
S80-S89 Injuries to the knee and lower leg	0.645	0.355
I30 Acute pericarditis	0.644	0.356
O23.4 Unspecified infection of urinary tract in pregnancy	0.644	0.356
C79.7 Secondary malignant neoplasm of adrenal gland	0.643	0.356
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.643	0.357
O36.4 Maternal care for intra-uterine death	0.643	0.357
O36.3 Maternal care for signs of foetal hypoxia	0.643	0.357
O36.2 Maternal care for hydrops foetalis	0.643	0.357
O36.1 Maternal care for other isoimmunisation	0.643	0.357
O40 Polyhydramnios	0.643	0.357
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.643	0.357
X58-X59 Accidental exposure to other and unspecified factors	0.643	0.357
C64-C68 Malignant neoplasms of urinary tract	0.641	0.358
S32.4 Fracture of acetabulum	0.641	0.358
S27.2 Traumatic heamopneumothorax	0.641	0.359
D73 Diseases of spleen	0.641	0.359
O60-O75 Complications of labour and delivery	0.640	0.360
S62.8 Fracture of other and unspecified parts of wrist and hand	0.640	0.360
I72 Other aneurysm	0.640	0.360
T40.2 Other opioids	0.639	0.361
J98.8 Other specified respiratory disorders	0.639	0.361
T14 Injury of unspecified body region	0.639	0.361
I05 Rheumatic mitral valve diseases	0.639	0.361
S90-S99 Injuries to the ankle and foot	0.639	0.361
T51.9 Alcohol, unspecified	0.638	0.362
Q82.8 Other specified congenital malformations of skin	0.637	0.363
T32 Corrosions classified according to extent of body surface involved	0.634	0.365
T30 Burn and corrosion, body region unspecified	0.634	0.365
T29 Burns and corrosions of multiple body regions	0.634	0.365
D68 Other coagulation defects	0.634	0.366
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.634	0.366
J84.8 Other specified interstitial pulmonary diseases	0.633	0.367
C50.8 Overlapping lesion of breast	0.632	0.368
O43.8 Other placental disorders	0.631	0.369
J98.9 Respiratory disorder, unspecified	0.630	0.369
J98.6 Disorders of diaphragm	0.630	0.369
J98.5 Diseases of mediastinum, not elsewhere classified	0.630	0.369
J98.3 Compensatory emphysema	0.630	0.369
J98.2 Interstitial emphysema	0.630	0.369
C80 Malignant neoplasm without specification of site	0.630	0.370
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.630	0.370
S26 Injury of heart	0.630	0.370
S25 Injury of blood vessels of thorax	0.630	0.370
S24 Injury of nerves and spinal cord at thorax level	0.630	0.370
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.630	0.370
S21 Open wound of thorax	0.630	0.370
T51.8 Other alcohols	0.629	0.371
T51.3 Fusel oil	0.629	0.371
T51.2 2-Propanol	0.629	0.371
T51.1 Methanol	0.629	0.371
O36.9 Maternal care for foetal problem, unspecified	0.629	0.371
J84.1 Other interstitial pulmonary diseases with fibrosis	0.629	0.371
I78 Diseases of capillaries	0.628	0.371
Q89 Other congenital malformations, not elsewhere classified	0.627	0.373
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.627	0.373
Q84 Other congenital malformations of integument	0.627	0.373
Q83 Congenital malformations of breast	0.627	0.373
Q81 Epidermolysis bullosa	0.627	0.373
Q80 Congenital ichthyosis	0.627	0.373
I08.1 Disorders of both mitral and tricuspid valves	0.626	0.374
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.625	0.375
X40-X49 Accidental poisoning by and exposure to noxious substances	0.625	0.375
X62.9 Unspecified place	0.624	0.376
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.623	0.377
J60-J70 Lung diseases due to external agents	0.622	0.378
I60.9 Subarachnoid haemorrhage, unspecified	0.622	0.378
Y35-Y36 Legal intervention and operations of war	0.621	0.379
Y10-Y34 Event of undetermined intent	0.621	0.379
Y00-Y09 Assault	0.621	0.379
X85-X99 Assault	0.621	0.379
X50-X57 Overexertion, travel and privation	0.621	0.379
X30-X39 Exposure to forces of nature	0.621	0.379
X20-X29 Contact with venomous animals and plants	0.621	0.379
X10-X19 Contact with heat and hot substances	0.621	0.379
X00-X09 Exposure to smoke, fire and flames	0.621	0.379
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.621	0.379
W75-W84 Other accidental threats to breathing	0.621	0.379
W65-W74 Accidental drowning and submersion	0.621	0.379
W50-W64 Exposure to animate mechanical forces	0.621	0.379
V98-V99 Other and unspecified transport accidents	0.621	0.379
V95-V97 Air and space transport accidents	0.621	0.379
V90-V94 Water transport accidents	0.621	0.379
V70-V79 Bus occupant injured in transport accident	0.621	0.379
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.621	0.379
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.621	0.379
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.621	0.379
V01-V09 Pedestrian injured in transport accident	0.621	0.379
Chapter I Certain infectious and parasitic diseases	0.620	0.380
Y57 Other and unspecified drugs and medicaments	0.620	0.380
S73.0 Dislocation of hip	0.619	0.381
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.617	0.383
I24 Other acute ischaemic heart diseases	0.617	0.383
T13 Other injuries of lower limb, level unspecified	0.616	0.384
Q85 Phakomatoses, not elsewhere classified	0.615	0.384
S62.5 Fracture of thumb	0.614	0.386
Q17 Other congenital malformations of ear	0.613	0.387
Q16 Congenital malformations of ear causing impairment of hearing	0.613	0.387
Q15 Other congenital malformations of eye	0.613	0.387
Q14 Congenital malformations of posterior segment of eye	0.613	0.387
Q13 Congenital malformations of anterior segment of eye	0.613	0.387
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.613	0.387
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.613	0.387
S27.3 Other injuries of lung	0.613	0.387
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.613	0.387
S66.8 Injury of other muscles and tendons at wrist and hand level	0.613	0.387
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.613	0.387
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.613	0.387
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.613	0.387
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.613	0.387
V80-V89 Other land transport accidents	0.612	0.388
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.612	0.388
C10 Malignant neoplasm of oropharynx	0.612	0.388
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.611	0.389
J14 Pneumonia due to Haemophilus influenzae	0.610	0.390
I35 Nonrheumatic aortic valve disorders	0.610	0.390
I99 Other and unspecified disorders of circulatory system	0.610	0.390
S50.9 Superficial injury of forearm, unspecified	0.609	0.390
S72.00 Fracture of neck of femur (closed)	0.609	0.391
C50.3 Lower-inner quadrant of breast	0.609	0.391
D84 Other immunodeficiencies	0.609	0.391
I51.8 Other ill-defined heart diseases	0.609	0.391
I73.8 Other specified peripheral vascular diseases	0.608	0.392
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.608	0.392
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.607	0.393
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.606	0.394
S59 Other and unspecified injuries of forearm	0.605	0.395
S58 Traumatic amputation of forearm	0.605	0.395
S57 Crushing injury of forearm	0.605	0.395
S56 Injury of muscle and tendon at forearm level	0.605	0.395
S55 Injury of blood vessels at forearm level	0.605	0.395
S54 Injury of nerves at forearm level	0.605	0.395
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.605	0.395
Y48 Anaesthetics and therapeutic gases	0.605	0.395
S27.0 Traumatic pneumothorax	0.604	0.396
D86 Sarcoidosis	0.604	0.396
X78 Intentional self-harm by sharp object	0.603	0.397
I42.1 Obstructive hypertrophic cardiomyopathy	0.603	0.397
C02 Malignant neoplasm of other and unspecified parts of tongue	0.602	0.398
O34 Maternal care for known or suspected abnormality of pelvic organs	0.602	0.398
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.602	0.398
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.602	0.398
S51 Open wound of forearm	0.602	0.398
J10 Influenza due to identified influenza virus	0.601	0.398
I09 Other rheumatic heart diseases	0.601	0.399
I06 Rheumatic aortic valve diseases	0.601	0.399
D47.1 Chronic myeloproliferative disease	0.599	0.401
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.598	0.401
C49 Malignant neoplasm of other connective and soft tissue	0.598	0.402
S61.9 Open wound of wrist and hand, part unspecified	0.598	0.402
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.598	0.402
S72.3 Fracture of shaft of femur	0.597	0.402
C50.0 Nipple and areola	0.596	0.404
D47.2 Monoclonal gammopathy	0.595	0.405
C71.7 Brain stem	0.595	0.405
C71.6 Cerebellum	0.595	0.405
C71.5 Cerebral ventricle	0.595	0.405
C71.4 Occipital lobe	0.595	0.405
C71.0 Cerebrum, except lobes and ventricles	0.595	0.405
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.594	0.406
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.593	0.406
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.593	0.406
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.593	0.406
D69 Purpura and other haemorrhagic conditions	0.593	0.407
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.593	0.407
C69.3 Choroid	0.593	0.407
S48 Traumatic amputation of shoulder and upper arm	0.592	0.408
S46 Injury of muscle and tendon at shoulder and upper arm level	0.592	0.408
S45 Injury of blood vessels at shoulder and upper arm level	0.592	0.408

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations