TreeWAS – Variant ID: rs10455590

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S52.60 Fracture of lower end of both ulna and radius (closed)	0.000	0.957	0.043
K85.9 Acute pancreatitis, unspecified	0.027	0.973	0.000
K37 Unspecified appendicitis	0.023	0.977	0.000
K85 Acute pancreatitis	0.018	0.982	0.000
L53.9 Erythematous condition, unspecified	0.000	0.983	0.017
K85.2 Alcohol-induced acute pancreatitis	0.017	0.983	0.000
K85.0 Idiopathic acute pancreatitis	0.015	0.984	0.000
K85.3 Drug-induced acute pancreatitis	0.013	0.987	0.000
S52.6 Fracture of lower end of both ulna and radius	0.000	0.987	0.013
H25.1 Senile nuclear cataract	0.000	0.987	0.013
K85.8 Other acute pancreatitis	0.013	0.987	0.000
K35-K38 Diseases of appendix	0.012	0.988	0.000
K36 Other appendicitis	0.011	0.989	0.000
K38.8 Other specified diseases of appendix	0.010	0.989	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.010	0.990	0.000
K38 Other diseases of appendix	0.010	0.990	0.000
K38.0 Hyperplasia of appendix	0.009	0.991	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.009	0.991	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.008	0.992	0.000
M47.82 Other spondylosis (Cervical region)	0.008	0.992	0.000
K38.3 Fistula of appendix	0.008	0.992	0.000
K38.2 Diverticulum of appendix	0.008	0.992	0.000
Q63.0 Accessory kidney	0.007	0.993	0.000
Q63 Other congenital malformations of kidney	0.007	0.993	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.007	0.993	0.000
K38.9 Disease of appendix, unspecified	0.007	0.993	0.000
Q63.2 Ectopic kidney	0.006	0.993	0.000
M94.88 Other specified disorders of cartilage (Other)	0.006	0.993	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.006	0.994	0.000
M54.22 Cervicalgia (Cervical region)	0.000	0.994	0.006
S52.61 Fracture of lower end of both ulna and radius (open)	0.000	0.994	0.006
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.006	0.994	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.006	0.994	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.006	0.994	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.006	0.994	0.000
M94.8 Other specified disorders of cartilage	0.006	0.994	0.000
C82.3 Follicular lymphoma grade IIIa	0.006	0.994	0.000
M17.0 Primary gonarthrosis, bilateral	0.006	0.994	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.006	0.994	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.000	0.994	0.006
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.994	0.006
K85.1 Biliary acute pancreatitis	0.005	0.994	0.000
Z83.3 Family history of diabetes mellitus	0.005	0.995	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.005	0.995	0.000
Q63.3 Hyperplastic and giant kidney	0.005	0.995	0.000
Q63.8 Other specified congenital malformations of kidney	0.005	0.995	0.000
C82.6 Cutaneous follicle centre lymphoma	0.005	0.995	0.000
C82.5 Diffuse follicle centre lymphoma	0.005	0.995	0.000
C82.0 Small cleaved cell, follicular	0.005	0.995	0.000
K38.1 Appendicular concretions	0.005	0.995	0.000
S42.00 Fracture of clavicle (closed)	0.000	0.995	0.005
S62.30 Fracture of other metacarpal bone (closed)	0.005	0.995	0.000
M94.81 Other specified disorders of cartilage (Shoulder region)	0.005	0.995	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.005	0.995	0.000
Q05.9 Spina bifida, unspecified	0.005	0.995	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.005	0.995	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.005	0.995	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.005	0.995	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.005	0.995	0.000
C82.4 Follicular lymphoma grade IIIb	0.005	0.995	0.000
M94.84 Other specified disorders of cartilage (Hand)	0.004	0.995	0.000
M94.83 Other specified disorders of cartilage (Forearm)	0.004	0.995	0.000
M94.82 Other specified disorders of cartilage (Upper arm)	0.004	0.995	0.000
M94.80 Other specified disorders of cartilage (Multiple sites)	0.004	0.995	0.000
Q05 Spina bifida	0.005	0.995	0.000
Q60-Q64 Congenital malformations of the urinary system	0.005	0.995	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.000	0.995	0.005
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.000	0.995	0.005
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.004	0.996	0.000
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.004	0.996	0.000
D37.5 Rectum	0.000	0.996	0.004
C82.2 Large cell, follicular	0.004	0.996	0.000
T86.1 Kidney transplant failure and rejection	0.000	0.996	0.004
Q05.4 Unspecified spina bifida with hydrocephalus	0.004	0.996	0.000
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.004	0.996	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.000	0.996	0.004
Q00-Q07 Congenital malformations of the nervous system	0.004	0.996	0.000
Q64 Other congenital malformations of urinary system	0.004	0.996	0.000
L53 Other erythematous conditions	0.000	0.996	0.004
Q05.7 Lumbar spina bifida without hydrocephalus	0.004	0.996	0.000
M46 Other inflammatory spondylopathies	0.004	0.996	0.000
M47.8 Other spondylosis	0.004	0.996	0.000
M94.89 Other specified disorders of cartilage (Site unspecified)	0.004	0.996	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.004	0.996	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.004	0.996	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.004	0.996	0.000
M46.2 Osteomyelitis of vertebra	0.004	0.996	0.000
T86 Failure and rejection of transplanted organs and tissues	0.000	0.996	0.004
Q05.8 Sacral spina bifida without hydrocephalus	0.003	0.996	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.003	0.996	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.003	0.996	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.003	0.996	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.003	0.996	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.003	0.996	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.003	0.996	0.000
M47.84 Other spondylosis (Thoracic region)	0.004	0.996	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.003	0.997	0.000
M47.89 Other spondylosis (Site unspecified)	0.003	0.997	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.000	0.997	0.003
Q07 Other congenital malformations of nervous system	0.003	0.997	0.000
H49.0 Third [oculomotor] nerve palsy	0.003	0.997	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.003	0.997	0.000
Q62.5 Duplication of ureter	0.003	0.997	0.000
M46.24 Osteomyelitis of vertebra (Thoracic region)	0.003	0.997	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.003	0.997	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.003	0.997	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.003	0.997	0.000
Q06 Other congenital malformations of spinal cord	0.003	0.997	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.003	0.997	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.003	0.997	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.003	0.997	0.000
Q04 Other congenital malformations of brain	0.003	0.997	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.003	0.997	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.003	0.997	0.000
Q64.8 Other specified congenital malformations of urinary system	0.003	0.997	0.000
Q64.6 Congenital diverticulum of bladder	0.003	0.997	0.000
Q64.5 Congenital absence of bladder and urethra	0.003	0.997	0.000
Q64.4 Malformation of urachus	0.003	0.997	0.000
Q64.2 Congenital posterior urethral valves	0.003	0.997	0.000
Q64.1 Exstrophy of urinary bladder	0.003	0.997	0.000
Q64.0 Epispadias	0.003	0.997	0.000
Q01 Encephalocele	0.003	0.997	0.000
Q00 Anencephaly and similar malformations	0.003	0.997	0.000
Q02 Microcephaly	0.003	0.997	0.000
L53.3 Other chronic figurate erythema	0.000	0.997	0.003
L53.2 Erythema marginatum	0.000	0.997	0.003
L53.1 Erythema annulare centrifugum	0.000	0.997	0.003
M46.8 Other specified inflammatory spondylopathies	0.003	0.997	0.000
M46.5 Other infective spondylopathies	0.003	0.997	0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.003	0.997	0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.000	0.997	0.003
M46.26 Osteomyelitis of vertebra (Lumbar region)	0.003	0.997	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.997	0.000
Q62.8 Other congenital malformations of ureter	0.003	0.997	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.003	0.997	0.000
Q62.6 Malposition of ureter	0.003	0.997	0.000
Q62.4 Agenesis of ureter	0.003	0.997	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.003	0.997	0.000
Q62.2 Congenital megaloureter	0.003	0.997	0.000
Q62.0 Congenital hydronephrosis	0.003	0.997	0.000
M25.76 Osteophyte (Lower leg)	0.000	0.997	0.003
Q60.0 Renal agenesis, unilateral	0.003	0.997	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.003	0.997	0.000
M21.3 Wrist or foot drop (acquired)	0.003	0.997	0.000
Q07.8 Other specified congenital malformations of nervous system	0.003	0.997	0.000
Q60.2 Renal agenesis, unspecified	0.003	0.997	0.000
Q62.1 Atresia and stenosis of ureter	0.003	0.997	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.000	0.997	0.003
M46.4 Discitis, unspecified	0.003	0.997	0.000
Z89.6 Acquired absence of leg above knee	0.000	0.997	0.003
Q60.6 Potter's syndrome	0.003	0.997	0.000
Q60.5 Renal hypoplasia, unspecified	0.003	0.997	0.000
Q60.4 Renal hypoplasia, bilateral	0.003	0.997	0.000
Q60.3 Renal hypoplasia, unilateral	0.003	0.997	0.000
Q60.1 Renal agenesis, bilateral	0.003	0.997	0.000
T86.4 Liver transplant failure and rejection	0.000	0.997	0.003
Q03 Congenital hydrocephalus	0.003	0.997	0.000
Q65 Congenital deformities of hip	0.003	0.997	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.003	0.997	0.000
M46.0 Spinal enthesopathy	0.003	0.997	0.000
M46.29 Osteomyelitis of vertebra (Site unspecified)	0.003	0.997	0.000
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M46.27 Osteomyelitis of vertebra (Lumbosacral region)	0.003	0.997	0.000
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)	0.003	0.997	0.000
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)	0.003	0.997	0.000
M46.22 Osteomyelitis of vertebra (Cervical region)	0.003	0.997	0.000
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)	0.003	0.997	0.000
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)	0.003	0.997	0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.000	0.997	0.003
T86.3 Heart-lung transplant failure and rejection	0.000	0.997	0.003
T86.2 Heart transplant failure and rejection	0.000	0.997	0.003
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
R44.1 Visual hallucinations	0.003	0.997	0.000
T86.0 Bone-marrow transplant rejection	0.000	0.997	0.003
Q07.0 Arnold-Chiari syndrome	0.003	0.997	0.000
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.000	0.997	0.003
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.000	0.997	0.003
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.000	0.997	0.003
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.000	0.997	0.003
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.000	0.997	0.003
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.000	0.997	0.003
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.000	0.997	0.003
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.000	0.997	0.003
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)	0.003	0.997	0.000
Q07.9 Congenital malformation of nervous system, unspecified	0.003	0.997	0.000
Q18 Other congenital malformations of face and neck	0.003	0.997	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.003	0.997	0.000
S42.0 Fracture of clavicle	0.000	0.997	0.003
Q16 Congenital malformations of ear causing impairment of hearing	0.003	0.997	0.000
L53.0 Toxic erythema	0.000	0.997	0.002
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.997	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.003	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.003	0.997	0.000
Q04.6 Congenital cerebral cysts	0.002	0.997	0.000
Q06.9 Congenital malformation of spinal cord, unspecified	0.002	0.997	0.000
Q06.4 Hydromyelia	0.002	0.997	0.000
Q06.3 Other congenital cauda equina malformations	0.002	0.997	0.000
Q06.2 Diastematomyelia	0.002	0.997	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.002	0.997	0.000
Q06.0 Amyelia	0.002	0.997	0.000
R44.0 Auditory hallucinations	0.003	0.997	0.000
Z63.4 Disappearance and death of family member	0.003	0.997	0.000
G96.0 Cerebrospinal fluid leak	0.000	0.997	0.003
Q18.1 Preauricular sinus and cyst	0.002	0.997	0.000
Q74 Other congenital malformations of limb(s)	0.002	0.997	0.000
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)	0.002	0.997	0.000
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)	0.002	0.997	0.000
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)	0.002	0.997	0.000
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)	0.002	0.997	0.000
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)	0.002	0.997	0.000
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)	0.002	0.997	0.000
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)	0.002	0.997	0.000
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)	0.002	0.997	0.000
Q04.9 Congenital malformation of brain, unspecified	0.002	0.997	0.000
Q04.5 Megalencephaly	0.002	0.997	0.000
Q04.4 Septo-optic dysplasia	0.002	0.997	0.000
Q04.3 Other reduction deformities of brain	0.002	0.997	0.000
Q04.2 Holoprosencephaly	0.002	0.997	0.000
Q04.1 Arhinencephaly	0.002	0.997	0.000
Q04.0 Congenital malformations of corpus callosum	0.002	0.997	0.000
M46.47 Discitis, unspecified (Lumbosacral region)	0.002	0.997	0.000
G72.9 Myopathy, unspecified	0.002	0.997	0.000
Q00.2 Iniencephaly	0.002	0.997	0.000
Q00.1 Craniorachischisis	0.002	0.997	0.000
Q00.0 Anencephaly	0.002	0.997	0.000
Q01.9 Encephalocele, unspecified	0.002	0.997	0.000
Q01.8 Encephalocele of other sites	0.002	0.997	0.000
Q01.2 Occipital encephalocele	0.002	0.997	0.000
Q01.1 Nasofrontal encephalocele	0.002	0.997	0.000
Q01.0 Frontal encephalocele	0.002	0.997	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.002	0.997	0.000
Q65.8 Other congenital deformities of hip	0.002	0.997	0.000
M46.59 Other infective spondylopathies (Site unspecified)	0.002	0.998	0.000
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M46.57 Other infective spondylopathies (Lumbosacral region)	0.002	0.998	0.000
M46.56 Other infective spondylopathies (Lumbar region)	0.002	0.998	0.000
M46.55 Other infective spondylopathies (Thoracolumbar region)	0.002	0.998	0.000
M46.54 Other infective spondylopathies (Thoracic region)	0.002	0.998	0.000
M46.53 Other infective spondylopathies (Cervicothoracic region)	0.002	0.998	0.000
M46.52 Other infective spondylopathies (Cervical region)	0.002	0.998	0.000
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)	0.002	0.998	0.000
M46.50 Other infective spondylopathies (Multiple sites in spine)	0.002	0.998	0.000
M46.89 Other specified inflammatory spondylopathies (Site unspecified)	0.002	0.998	0.000
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)	0.002	0.998	0.000
M46.86 Other specified inflammatory spondylopathies (Lumbar region)	0.002	0.998	0.000
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)	0.002	0.998	0.000
M46.84 Other specified inflammatory spondylopathies (Thoracic region)	0.002	0.998	0.000
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)	0.002	0.998	0.000
M46.82 Other specified inflammatory spondylopathies (Cervical region)	0.002	0.998	0.000
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)	0.002	0.998	0.000
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)	0.002	0.998	0.000
Q04.8 Other specified congenital malformations of brain	0.002	0.998	0.000
M94 Other disorders of cartilage	0.002	0.998	0.000
Q17 Other congenital malformations of ear	0.002	0.998	0.000
Q15 Other congenital malformations of eye	0.002	0.998	0.000
Q13 Congenital malformations of anterior segment of eye	0.002	0.998	0.000
Q16.9 Congenital malformation of ear causing impairment of hearing, unspecified	0.002	0.998	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.002	0.998	0.000
Q12 Congenital lens malformations	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
M46.49 Discitis, unspecified (Site unspecified)	0.002	0.998	0.000
M46.42 Discitis, unspecified (Cervical region)	0.002	0.998	0.000
M46.40 Discitis, unspecified (Multiple sites in spine)	0.002	0.998	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.002	0.998	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.002	0.998	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.002	0.998	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.002	0.998	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.002	0.998	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.002	0.998	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.002	0.998	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.002	0.998	0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.002	0.998	0.000
Q89.2 Congenital malformations of other endocrine glands	0.002	0.998	0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M46.45 Discitis, unspecified (Thoracolumbar region)	0.002	0.998	0.000
M46.43 Discitis, unspecified (Cervicothoracic region)	0.002	0.998	0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.002	0.998	0.000
Q03.8 Other congenital hydrocephalus	0.002	0.998	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.002	0.998	0.000
Q65.9 Congenital deformity of hip, unspecified	0.002	0.998	0.000
Q65.6 Unstable hip	0.002	0.998	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.002	0.998	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.002	0.998	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.002	0.998	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.002	0.998	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.002	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.002	0.998	0.000
M46.09 Spinal enthesopathy (Site unspecified)	0.002	0.998	0.000
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M46.07 Spinal enthesopathy (Lumbosacral region)	0.002	0.998	0.000
M46.05 Spinal enthesopathy (Thoracolumbar region)	0.002	0.998	0.000
M46.04 Spinal enthesopathy (Thoracic region)	0.002	0.998	0.000
M46.03 Spinal enthesopathy (Cervicothoracic region)	0.002	0.998	0.000
M46.02 Spinal enthesopathy (Cervical region)	0.002	0.998	0.000
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)	0.002	0.998	0.000
M46.00 Spinal enthesopathy (Multiple sites in spine)	0.002	0.998	0.000
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral	0.002	0.998	0.000
M46.16 Sacroiliitis, not elsewhere classified-Lumbar	0.002	0.998	0.000
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar	0.002	0.998	0.000
M46.14 Sacroiliitis, not elsewhere classified-Thoracic	0.002	0.998	0.000
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic	0.002	0.998	0.000
M46.12 Sacroiliitis, not elsewhere classified-Cervical	0.002	0.998	0.000
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl	0.002	0.998	0.000
M46.10 Sacroiliitis, not elsewhere classified-Mult site	0.002	0.998	0.000
Q96 Turner's syndrome	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
Q14.1 Congenital malformation of retina	0.002	0.998	0.000
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)	0.002	0.998	0.000
M46.19 Sacroiliitis, not elsewhere classified-Site unspe	0.002	0.998	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.002	0.998	0.000
Q30 Congenital malformations of nose	0.002	0.998	0.000
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
M46.44 Discitis, unspecified (Thoracic region)	0.002	0.998	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.002	0.998	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.000	0.998	0.002
I11 Hypertensive heart disease	0.000	0.998	0.002
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.002	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.002	0.998	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.002	0.998	0.000
Q18.8 Other specified congenital malformations of face and neck	0.002	0.998	0.000
Q18.7 Microcheilia	0.002	0.998	0.000
Q18.6 Macrocheilia	0.002	0.998	0.000
Q18.5 Microstomia	0.002	0.998	0.000
Q18.4 Macrostomia	0.002	0.998	0.000
Q18.3 Webbing of neck	0.002	0.998	0.000
Q18.2 Other branchial cleft malformations	0.002	0.998	0.000
Q89 Other congenital malformations, not elsewhere classified	0.002	0.998	0.000
S42.01 Fracture of clavicle (open)	0.000	0.998	0.002
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.002	0.998	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.002	0.998	0.000
Q16.5 Congenital malformation of inner ear	0.002	0.998	0.000
Q16.4 Other congenital malformations of middle ear	0.002	0.998	0.000
Q16.3 Congenital malformation of ear ossicles	0.002	0.998	0.000
Q16.2 Absence of eustachian tube	0.002	0.998	0.000
Q16.1 Congenital absence, atresia and stricture of auditory canal (external)	0.002	0.998	0.000
Q16.0 Congenital absence of (ear) auricle	0.002	0.998	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.002	0.998	0.000
Q34 Other congenital malformations of respiratory system	0.002	0.998	0.000
Q33 Congenital malformations of lung	0.002	0.998	0.000
Q32 Congenital malformations of trachea and bronchus	0.002	0.998	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.002	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.002	0.998	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.002	0.998	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.002	0.998	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.002	0.998	0.000
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.002	0.998	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.002	0.998	0.000
Q14.3 Congenital malformation of choroid	0.002	0.998	0.000
Q14.2 Congenital malformation of optic disk	0.002	0.998	0.000
Q14.0 Congenital malformation of vitreous humour	0.002	0.998	0.000
Q31 Congenital malformations of larynx	0.002	0.998	0.000
M46.06 Spinal enthesopathy (Lumbar region)	0.002	0.998	0.000
Q25.3 Stenosis of aorta	0.002	0.998	0.000
Q96.9 Turner's syndrome, unspecified	0.002	0.998	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.002	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.998	0.000
C53.9 Cervix uteri, unspecified	0.002	0.998	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.002	0.998	0.000
Q10.0 Congenital ptosis	0.002	0.998	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.002	0.998	0.000
Q80-Q89 Other congenital malformations	0.002	0.998	0.000
H35.8 Other specified retinal disorders	0.000	0.998	0.002
Q25.4 Other congenital malformations of aorta	0.002	0.998	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.002	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.002	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.002	0.998	0.000
Q25 Congenital malformations of great arteries	0.002	0.998	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.002	0.998	0.000
L53.8 Other specified erythematous conditions	0.001	0.998	0.001
Q10.7 Congenital malformation of orbit	0.002	0.998	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.002	0.998	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.002	0.998	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.002	0.998	0.000
Q10.3 Other congenital malformations of eyelid	0.002	0.998	0.000
Q10.2 Congenital entropion	0.002	0.998	0.000
Q10.1 Congenital ectropion	0.002	0.998	0.000
Y89.9 Sequelae of unspecified external cause	0.002	0.998	0.000
M94.3 Chondrolysis	0.002	0.998	0.000
M94.1 Relapsing polychondritis	0.002	0.998	0.000
Q30.3 Congenital perforated nasal septum	0.002	0.998	0.000
Q70.3 Webbed toes	0.002	0.998	0.000
Q74.1 Congenital malformation of knee	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
I15.1 Hypertension secondary to other renal disorders	0.000	0.998	0.002
Q13.9 Congenital malformation of anterior segment of eye, unspecified	0.002	0.998	0.000
Q13.8 Other congenital malformations of anterior segment of eye	0.002	0.998	0.000
Q13.5 Blue sclera	0.002	0.998	0.000
Q13.4 Other congenital corneal malformations	0.002	0.998	0.000
Q13.3 Congenital corneal opacity	0.002	0.998	0.000
Q13.2 Other congenital malformations of iris	0.002	0.998	0.000
Q13.1 Absence of iris	0.002	0.998	0.000
Q13.0 Coloboma of iris	0.002	0.998	0.000
Q15.9 Congenital malformation of eye, unspecified	0.002	0.998	0.000
Q15.8 Other specified congenital malformations of eye	0.002	0.998	0.000
Q15.0 Congenital glaucoma	0.002	0.998	0.000
Q17.9 Congenital malformation of ear, unspecified	0.002	0.998	0.000
Q17.8 Other specified congenital malformations of ear	0.002	0.998	0.000
Q17.4 Misplaced ear	0.002	0.998	0.000
Q17.3 Other misshapen ear	0.002	0.998	0.000
Q17.2 Microtia	0.002	0.998	0.000
Q17.1 Macrotia	0.002	0.998	0.000
Q17.0 Accessory auricle	0.002	0.998	0.000
S62.3 Fracture of other metacarpal bone	0.002	0.998	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.000	0.998	0.002
Q17.5 Prominent ear	0.002	0.998	0.000
S49.8 Other specified injuries of shoulder and upper arm	0.000	0.998	0.002
M46.46 Discitis, unspecified (Lumbar region)	0.002	0.998	0.000
Q12.9 Congenital lens malformation, unspecified	0.002	0.998	0.000
Q12.8 Other congenital lens malformations	0.002	0.998	0.000
Q12.4 Spherophakia	0.002	0.998	0.000
Q12.3 Congenital aphakia	0.002	0.998	0.000
Q12.2 Coloboma of lens	0.002	0.998	0.000
Q12.1 Congenital displaced lens	0.002	0.998	0.000
Q67.8 Other congenital deformities of chest	0.002	0.998	0.000
Q67.7 Pectus carinatum	0.002	0.998	0.000
Q67.3 Plagiocephaly	0.002	0.998	0.000
Q67.2 Dolichocephaly	0.002	0.998	0.000
Q67.1 Compression facies	0.002	0.998	0.000
Q67.0 Facial asymmetry	0.002	0.998	0.000
Z89.9 Acquired absence of limb, unspecified	0.000	0.998	0.002
R44 Other symptoms and signs involving general sensations and perceptions	0.002	0.998	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
H35.0 Background retinopathy and retinal vascular changes	0.000	0.998	0.002
M94.0 Chondrocostal junction syndrome [Tietze]	0.002	0.998	0.000
Z63 Other problems related to primary support group, including family circumstances	0.002	0.998	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.000	0.998	0.002
I65.2 Occlusion and stenosis of carotid artery	0.000	0.998	0.002
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.998	0.000
Q70.9 Syndactyly, unspecified	0.002	0.998	0.000
Q70.4 Polysyndactyly	0.002	0.998	0.000
Q70.2 Fused toes	0.002	0.998	0.000
Q70.1 Webbed fingers	0.002	0.998	0.000
Q70.0 Fused fingers	0.002	0.998	0.000
Q96.8 Other variants of Turner's syndrome	0.002	0.998	0.000
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.002	0.998	0.000
Q96.3 Mosaicism, 45,X/46,XX or XY	0.002	0.998	0.000
Q96.2 Karyotype 46,X with abnormal sex chromosome, except iso (Xq)	0.002	0.998	0.000
Q96.1 Karyotype 46,X iso (Xq)	0.002	0.998	0.000
Q96.0 Karyotype 45,X	0.002	0.998	0.000
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.002	0.998	0.000
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.002	0.998	0.000
Q98.7 Male with sex chromosome mosaicism	0.002	0.998	0.000
Q98.6 Male with structurally abnormal sex chromosome	0.002	0.998	0.000
Q98.5 Karyotype 47,XYY	0.002	0.998	0.000
Q98.3 Other male with 46,XX karyotype	0.002	0.998	0.000
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.002	0.998	0.000
Q98.1 Klinefelter's syndrome, male with more than two X chromosomes	0.002	0.998	0.000
Q98.0 Klinefelter's syndrome karyotype 47,XXY	0.002	0.998	0.000
Z63.7 Other stressful life events affecting family and household	0.002	0.998	0.000
Q90 Down's syndrome	0.002	0.998	0.000
Q12.0 Congenital cataract	0.002	0.998	0.000
Z63.5 Disruption of family by separation and divorce	0.002	0.998	0.000
Q36 Cleft lip	0.002	0.998	0.000
Q30.9 Congenital malformation of nose, unspecified	0.002	0.998	0.000
Q30.8 Other congenital malformations of nose	0.002	0.998	0.000
Q30.2 Fissured, notched and cleft nose	0.002	0.998	0.000
Q30.1 Agenesis and underdevelopment of nose	0.002	0.998	0.000
Q30.0 Choanal atresia	0.002	0.998	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.002	0.998	0.000
Q78.8 Other specified osteochondrodysplasias	0.002	0.998	0.000
Q78.6 Multiple congenital exostoses	0.002	0.998	0.000
Q78.5 Metaphyseal dysplasia	0.002	0.998	0.000
Q78.4 Enchondromatosis	0.002	0.998	0.000
Q78.3 Progressive diaphyseal dysplasia	0.002	0.998	0.000
Q78.2 Osteopetrosis	0.002	0.998	0.000
Q78.1 Polyostotic fibrous dysplasia	0.002	0.998	0.000
Q78.0 Osteogenesis imperfecta	0.002	0.998	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.998	0.002
Q69.9 Polydactyly, unspecified	0.002	0.998	0.000
Q69.2 Accessory toe(s)	0.002	0.998	0.000
Q69.1 Accessory thumb(s)	0.002	0.998	0.000
Q69.0 Accessory finger(s)	0.002	0.998	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.002	0.998	0.000
Q71.8 Other reduction defects of upper limb(s)	0.002	0.998	0.000
Q71.6 Lobster-claw hand	0.002	0.998	0.000
Q71.5 Longitudinal reduction defect of ulna	0.002	0.998	0.000
Q71.4 Longitudinal reduction defect of radius	0.002	0.998	0.000
Q71.3 Congenital absence of hand and finger(s)	0.002	0.998	0.000
Q71.2 Congenital absence of both forearm and hand	0.002	0.998	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.002	0.998	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.002	0.998	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.002	0.998	0.000
Q72.8 Other reduction defects of lower limb(s)	0.002	0.998	0.000
Q72.7 Split foot	0.002	0.998	0.000
Q72.6 Longitudinal reduction defect of fibula	0.002	0.998	0.000
Q72.5 Longitudinal reduction defect of tibia	0.002	0.998	0.000
Q72.4 Longitudinal reduction defect of femur	0.002	0.998	0.000
Q72.3 Congenital absence of foot and toe(s)	0.002	0.998	0.000
Q72.2 Congenital absence of both lower leg and foot	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations